Coupling of Permeabilized Microorganisms for Efficient Enantioselective Reduction of Ketone with...

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2006 Microbiological syntheses O 0035 Coupling of Permeabilized Microorganisms for Efficient Enantioselective Reduc- tion of Ketone with Cofactor Recycling. — Under optimized conditions, optically active compounds such as (R)-(II) and (+)-(IV) are obtained in high yields. — (ZHANG, J.; WITHOLT, B.; LI*, Z.; Chem. Commun. (Cambridge) 2006, 4, 398-400; Inst. Biotechnol., ETH-Hoenggerberg, CH-8093 Zuerich, Switz.; Eng.) — K. Schneider 20- 031

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2006

200620.fm Page 31 Thursday, April 13, 2006 1:02 PM

Microbiological synthesesO 0035 Coupling of Permeabilized Microorganisms for Efficient Enantioselective Reduc-

tion of Ketone with Cofactor Recycling. — Under optimized conditions, optically active compounds such as (R)-(II) and (+)-(IV) are obtained in high yields. — (ZHANG, J.; WITHOLT, B.; LI*, Z.; Chem. Commun. (Cambridge) 2006, 4, 398-400; Inst. Biotechnol., ETH-Hoenggerberg, CH-8093 Zuerich, Switz.; Eng.) —K. Schneider

20- 031