Could genomics save the world?
-
Upload
eagle-genomics-ltd -
Category
Technology
-
view
873 -
download
0
description
Transcript of Could genomics save the world?
![Page 1: Could genomics save the world?](https://reader033.fdocuments.us/reader033/viewer/2022052505/555011d5b4c90535638b4a8e/html5/thumbnails/1.jpg)
Could genomics save the world?
Will Spooner, CTO, Founder, Eagle Genomics Ltd [email protected]
Image: http://grayninja93.deviantart.com/art/Glow-125681900 CC-BY-NC-ND 3.0
![Page 2: Could genomics save the world?](https://reader033.fdocuments.us/reader033/viewer/2022052505/555011d5b4c90535638b4a8e/html5/thumbnails/2.jpg)
![Page 3: Could genomics save the world?](https://reader033.fdocuments.us/reader033/viewer/2022052505/555011d5b4c90535638b4a8e/html5/thumbnails/3.jpg)
Famine Disease
Image: A. Cavanagh http://images.wellcome.ac.uk/ CC-BY-ND 2.0
Image: http://transformergirl.deviantart.com/art/Famine-257996482 CC-BY-NC-ND 2.0
![Page 4: Could genomics save the world?](https://reader033.fdocuments.us/reader033/viewer/2022052505/555011d5b4c90535638b4a8e/html5/thumbnails/4.jpg)
Image http://widescreenwallpapers.org/earth-wallpapers.html CC-BY-NC-ND 3.0
SyntheticLife
Gaia
Image http://ginosblog.com/2010/06/03/100-synthetic-life-is-a-babystep-away/ CC-BY-NC-SA
![Page 5: Could genomics save the world?](https://reader033.fdocuments.us/reader033/viewer/2022052505/555011d5b4c90535638b4a8e/html5/thumbnails/5.jpg)
Molecular Psychiatry advance online publication 30 August 2011; doi:10.1038/mp.2011.101
Scientific impact of genomics
Image: Sartr http://sartr.deviantart.com/gallery/?offset=96#/d1u0z75 CC BY-NC-ND 3.0
Phen
otyp
e As
soci
ation
![Page 6: Could genomics save the world?](https://reader033.fdocuments.us/reader033/viewer/2022052505/555011d5b4c90535638b4a8e/html5/thumbnails/6.jpg)
PhenotypicAssociation[biomarker]
Stratified Medicine
Right drug
Right patient
Right time
Pharmacogenomics
Genotypic
Transcriptomic
Epigenetic
Genomics in medicine
©
![Page 7: Could genomics save the world?](https://reader033.fdocuments.us/reader033/viewer/2022052505/555011d5b4c90535638b4a8e/html5/thumbnails/7.jpg)
Genomics in plant breedingGermplasm/Pedigree
Phenotype/Genotype association
Phenotype Genotype
GenotypingPhenotyping
Assays
Breeding
![Page 8: Could genomics save the world?](https://reader033.fdocuments.us/reader033/viewer/2022052505/555011d5b4c90535638b4a8e/html5/thumbnails/8.jpg)
NGS - democratising genomics
$1000 genome~$0.01 Mbase (30x coverage)
![Page 9: Could genomics save the world?](https://reader033.fdocuments.us/reader033/viewer/2022052505/555011d5b4c90535638b4a8e/html5/thumbnails/9.jpg)
50,000 core supercomputer$1,600/HOUR
Cloud – democratising HPC
![Page 10: Could genomics save the world?](https://reader033.fdocuments.us/reader033/viewer/2022052505/555011d5b4c90535638b4a8e/html5/thumbnails/10.jpg)
Doing Genomics Efficiently
• “Genome Content Management is the set of processes and technologies that support the creating, managing, and reporting of genomic data.”
Create
Man
ag
e
Report
Create
Report
Ext
end
Manage
Share
Reuse
TIMELINE: Bespoke……...Common Models……………Content Management Systems
![Page 11: Could genomics save the world?](https://reader033.fdocuments.us/reader033/viewer/2022052505/555011d5b4c90535638b4a8e/html5/thumbnails/11.jpg)
Open Innovation
ExploreWork together to find a commonpurpose
NurtureBuild trust, shared language
ExploitTurn ideas intotangible benefits
CollaborateEnterpriseAcademiaGovernmentFoundations
©
![Page 12: Could genomics save the world?](https://reader033.fdocuments.us/reader033/viewer/2022052505/555011d5b4c90535638b4a8e/html5/thumbnails/12.jpg)
![Page 13: Could genomics save the world?](https://reader033.fdocuments.us/reader033/viewer/2022052505/555011d5b4c90535638b4a8e/html5/thumbnails/13.jpg)
–In under a month (June 2011);• 10 e coli isolates sequenced,• 9 genome assemblies released,• 16 genome annotations released,•Over 50 analyses performed,• Resulting in 12 citable publications
![Page 14: Could genomics save the world?](https://reader033.fdocuments.us/reader033/viewer/2022052505/555011d5b4c90535638b4a8e/html5/thumbnails/14.jpg)
Can genomics save the world?
• Genomics is revolutionising:– Basic research, – Plant breeding, – Healthcare.
• Genomics R&D is empowered by:– NGS, – Cloud computing,
• Collaboration is key– Open knowledge/science,– Public datasets,– Open innovation.
![Page 15: Could genomics save the world?](https://reader033.fdocuments.us/reader033/viewer/2022052505/555011d5b4c90535638b4a8e/html5/thumbnails/15.jpg)
Eagle Genomics
Genome Content ManagementIntegrated, Analysed, Validated,
Except where otherwise noted, this work is licensed under the Creative Commons Attribution 3.0 License
©