Costus igneus
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Transcript of Costus igneus
OR
INSULIN PLANT
PRESENTED BY :HARSHITA GUPTA
NATURAL PRODUCTS
NIPER AHMEDABAD,
GUJRAT.
COSTUS IGENUS
FLOW OF SEMINAR
INTRODUCTION DISTRIBUTION PHYTOCHEMISTRY BOTANICAL
DESCRIPTION BIOACTIVITY REFERENCE
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INTRODUCTION
Costus Igneus
Fiery Costus
Spiral flag Insulin plant
Chamaecostus cuspidatus
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Costus igneus a medicinal plant is a Magic Cure
for Diabetes.Insulin plant (Costus igneus) common name in Hindi is keukand and in Gujarati - pakarmula. In Marathi, Malayalam and Sanskrit is - pushkarmula and in Tamil is kostam.Family : Costaceae.Its leaves helps to build up insulin in the human body so it is commonly known as insulin plant in India.
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It is now accepted and used widely as an Ayurvedic medicinal herb.
Consumption of the leaves are believed to lower blood glucose levels.
Diabetics who consumed the leaves of this plant did report a fall in their blood glucose levels.
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Costus igneus is native to Southeast Asia, especially on the Greater Sunda Islands in Indonesia.It is a relatively new entrant to Kerala and India.This plant was grown in America and is becoming popular in India because of its medicinal chemicals.
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DISTRIBUTION
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C. igneus leaves
revealed that it is rich in
protein, iron, and
antioxidant components
such as ascorbic acid,
α‑tocopherol,
β‑carotene, terpinoids,
steroids, and flavonoids.
Methanolic extract was
found to contain the
highest number of
phytochemicals such as
carbohydrates,
triterpenoids, proteins,
alkaloids, tannins,
saponins, and flavonoids.
The ethanol extract
contained alkaloid also.
The major component of
the ether fraction was bis
(2’‑ethylhexyl)‑1,2‑benzen
edicarboxylate (59.04%)
apart from α‑tocopherol
and a steroid, ergastanol.
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PHYTOCHEMISTRY
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•Stem showed the presence of a terpenoid compound lupeol and a steroid compound stigmasterol.
•Bioactive compounds quercetin and diosgenin, a steroidal sapogenin, were isolated from C. igneus rhizome.
•phytochemical evaluation of Insulin plant revealed that the leaves contain 21.2% fibers. Successive extracts gave 5.2% extractives in petroleum ether, 1.06% in cyclohexane, 1.33% in acetone, and 2.95% in ethanol.
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CONT…..
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BOTANICAL DESCRIPTION
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A perennial,
upright,
spreading plant
reaching about
two
feet tall, with
spirally arranged
leaves and
attractive flowers.
Leaves- simple, alternate, entire,
oblong, evergreen, 4‑8 inches in
length.
Fruits- are inconspicuous, not
showy, less than 0.5 inch, and
green‑colored.
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Spiral flag grows in either full sun or
partial shade.
It needs fertile soil and ample moisture,
and is often planted near water.
The plant has no diseases are of major concern
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Growth and propagation
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BIOACTIVITY
Anti‑diabetic activity
Toxicity studyHypolipidemic
activityAnti‑cancer effect
Anti‑microbial activity
Antioxidant activity
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•In Ayurvedic treatment diabetes patients are advised to chew down the
Insulin plants leaves for a month.
•The patient has to take two leaves per day in the morning and evening for
one week.
The leaves must be
chewed well before
swallowing.
•After one week the patient should take one leaf each in the morning and
evening.
•This dosage should be continued for 30 days. Allopathic doctors too
recommend it and it is found to be effective in bringing blood sugar levels
under completely under control.
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ANTI-DIABETIC
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According to International Journal of Ayurveda Research a new study on Insulin plant
(Costus igneus) was published recently. The leaves of insulin plant (Costus igneus)
reduced the fasting and postprandial blood sugar levels, bringing them down towards
normal, in dexamethasone-induced hyperglycaemia in rats. Reduction in the fasting
and the postprandial blood sugar levels with leaves of insulin plant was comparable
with that obtained with Glibenclamide 500 µg/kg at 250 mg/kg/day and 500 mg/kg/day
of powdered leaves of the insulin plant(Costus igneus).
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Hardikar, M. R., Varma, M. E., kulkarni, A. A., Kulkarni, P. P. & Joshi, B. N.
2016. Elucidation of hypoglycemic action and toxicity studies of insulin-like
protein from Costus igneus. Phytochemistry, 124, 99-107.Kumudhavalli, M. & Jaykar, B. 2012. Evaluation of Antidiabetic activity of
Costus igneus (L) leaves on STZ induced diabetic rats. Der Pharmacia Sinica,
3, 1-4.Sataraddi, S. & Nandibewoor, S. 2012. Bio synthesis, characterization and
activity studies of Ag nanoparticles, by (Costus igneus) insulin plant extract.
Der Pharmacia Lettre, 4, 152-158.Ghaisas, S. M. 2011. Effect of insulin plant leaves on dexamethasone-
induced hyperglycemia. International journal of Ayurveda research, 2, 60.
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Krishnan, K., Vijayalakshmi, N. & Helen, A. 2011. Beneficial effects of
Costus igneus and dose response studies in streptozotocin induced diabetic
rats. International Journal of Current Pharmaceutical Research, 3, 42-6.
Krishnan, K., Vijayalekshmi, N. & Helen, A. 2011. Methanolic extract of
Costus igneus (NE Br) alleviates dyslipidemia in diabetic rats. Asian Journal
of Pharmaceutical and Clinical Research 4: 154-157.
Pazhanichamy, K., Aiswarya Devi, S., Jeba, S., Priya, G., Yogha, G.,
Manjula, K., Rajendran, K., Kumaran, S. & Eevera, T. 2011. The Efficacy of
Costus igneus Rhizome on Carbohydrate Metabolic, Hepatoproductive and
Antioxidative Enzymes in Streptozotocin-induced Diabetic Rats. Journal of
Health Science, 57, 37-46.
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Vishalakshi Devi, D. & Urooj, A. 2010. Nutrient profile and antioxidant
components of Costus speciosus Sm. and Costus igneus Nak. Indian Journal
of Natural Products and Resources, 1, 116-118.
Vishnu, B., Naveen, A., Akshay, K., Sikarwar, M. & Patil, M. 2010. Antidiabetic
activity of insulin plant (Costus igneus) leaf extract in diabetic rats. Journal of
Pharmacy Research, 3, 608-611.
Mani, P., Kumar, R. A., Bastin, T. J., Jenifer, S. & Arumugam, M. 2010.
Comparative evaluation of extracts of C. igneus (or C. pictus) for
hypoglycemic and hypolipidemic activity in alloxan diabetic rats. International
Journal of Pharmacy and Technology, 2, 183-195.
Shetty, A., Choudhury, D., Nair, V., Kuruvilla, M. & Kotian, S. 2010. Effect of
the insulin plant (Costus igneus) leaves on dexamethasone-induced
hyperglycemia. International Journal of Ayurveda research, 1, 100-102.
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