Cortidex Dosage & Drug Information _ MIMS
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Cortidex - Concise Prescribing Information Manufacturer Sanbe Contents Dexamethasone Indications Allergic states, collagen diseases, rheumatic disorders, leukemias, shock therapy, resp diseases, haematologic disorders, oedematous states . Dosage Tab Adult 0.5-9 mg in divided doses. Childn 6-12 yr 0.25-2 mg, 1-5 yr 0.25-1 mg, ≤1 yr 0.1-0.25 mg. To be given 2 times daily. Inj Intensive therapy or emergency 2-4 mg 6-8 times daily. Max daily dose: 50 mg. Shock condition 1-6 mg/kg body wt. Administration Should be taken with food. Contraindications Peptic ulcer, osteoporosis, psychoses or severe psychoneuroses, active or quiescent TB; acute infection; live vaccines. Special Precautions HTN, CHF, DM, infectious disease, chronic renal failure, uremia. Elderly; pregnancy. Adverse Drug Reactions Fluid & salt retention, edema, HTN; amenorrhea, hyperhidrosis; mental disturbances; acute pancreatitis; aseptic osteonecrosis; muscle weakness; Cushingoid state; raised IOP; visual disturbances; local atrophy; increased appetite; growth retardation. View ADR Monitoring Form Drug Interactions Efficacy may be reduced by phenytoin, phenobarbital, rifampicin, vit A, tetracyclines & other antibiotics, thiazides. Oral anticoagulants, oral hypoglycaemics & salicylates. View more drug interactions with Cortidex Pregnancy Category (US FDA) Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if the potential benefit justifies the potential risk to the foetus. (in 1st trimester) Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot be used or are ineffective). MIMS Class Corticosteroid Hormones ATC Classification H02AB02 - dexamethasone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations. Drug Classification G Presentation/Packing Form Packing/Price Cortidex inj 5 mg/mL (amp) 1 mL x 10 × 1's (Rp52,300/box) Cortidex tab 0.5 mg 10 × 10's (Rp20,500/box)
Transcript of Cortidex Dosage & Drug Information _ MIMS
Cortidex - Concise Prescribing InformationManufacturer Sanbe
Contents Dexamethasone
Indications Allergic states, collagen diseases, rheumatic disorders, leukemias, shock therapy, resp diseases, haematologic disorders,
oedematous states.
Dosage Tab Adult 0.5-9 mg in divided doses. Childn 6-12 yr 0.25-2 mg, 1-5 yr 0.25-1 mg, ≤1 yr 0.1-0.25 mg. To be given 2 times
daily. Inj Intensive therapy or emergency 2-4 mg 6-8 times daily. Max daily dose: 50 mg. Shock condition 1-6 mg/kg body wt.
Administration Should be taken with food.
Contraindications Peptic ulcer, osteoporosis, psychoses or severe psychoneuroses, active or quiescent TB; acute infection; live vaccines.
Special Precautions HTN, CHF, DM, infectious disease, chronic renal failure, uremia. Elderly; pregnancy.
Adverse Drug Reactions Fluid & salt retention, edema, HTN; amenorrhea, hyperhidrosis; mental disturbances; acute pancreatitis; aseptic
osteonecrosis; muscle weakness; Cushingoid state; raised IOP; visual disturbances; local atrophy; increased appetite;
growth retardation.
View ADR Monitoring Form
Drug Interactions Efficacy may be reduced by phenytoin, phenobarbital, rifampicin, vit A, tetracyclines & other antibiotics, thiazides. Oral
anticoagulants, oral hypoglycaemics & salicylates.
View more drug interactions with Cortidex
Pregnancy Category (US FDA)
Category C: Either studies in animals have revealed adverse effects on the foetus (teratogenic or embryocidal or other) and
there are no controlled studies in women or studies in women and animals are not available. Drugs should be given only if
the potential benefit justifies the potential risk to the foetus.
(in 1st trimester)
Category D: There is positive evidence of human foetal risk, but the benefits from use in pregnant women may be acceptable
despite the risk (e.g., if the drug is needed in a life-threatening situation or for a serious disease for which safer drugs cannot
be used or are ineffective).
MIMS Class Corticosteroid Hormones
ATC Classification H02AB02 - dexamethasone ; Belongs to the class of glucocorticoids. Used in systemic corticosteroid preparations.
Drug Classification G
Presentation/Packing
Form Packing/Price
Cortidex inj 5 mg/mL (amp) 1 mL x 10 × 1's (Rp52,300/box)
Cortidex tab 0.5 mg 10 × 10's (Rp20,500/box)
