Coordinated bacterial behaviour Swarming motilityBiofilm formation SymbiosisPathogenicity Fruit body...
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Coordinated bacterial behaviour Swarming motility Biofilm formation Symbiosis Pathogenicity Fruit body formation Bioluminescence Quorum Sensing = Intercellular Signaling Wound infection Skin diseases Yoghurt production
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Transcript of Coordinated bacterial behaviour Swarming motilityBiofilm formation SymbiosisPathogenicity Fruit body...
Coordinated bacterial behaviour
Swarming motilityBiofilm formation
Symbiosis Pathogenicity
Fruit bodyformation
Bioluminescence
Quorum Sensing= Intercellular Signaling
Wound infection Skin diseases
Yoghurt production
after 3 d on agar
activation
Sin quorum sensing: a system of transcription control
WT
sinI-
expR-
sinR-
QS behaviour
SinISinR
AHLs
AHLs
AHLs
AHLs
nutrient limitation
ExpRAHLs
AHLs
A more detaileddescription
SinISinR
ExpR
resting state
SinISinR
AHLs
ExpR
nutrient limitation
positive feedback
negative feedback
SinISinR
AHLs
AHLsExpR
SinR
AHLs
ExpRAHLs
expression of green fluorescent protein fromthe sinI promoter
0 10 20 300
5000
10000
15000
20000
sinI promoter-egfp fusion
time (hours)
F/c
ell
log growth intermediate growth stat. phase
resting state nutrient limitation activation positive feeback negative feedback
AHL concentration 0-5 nM 5-20 nM 20-1000 nMin growth medium:
SinISinR
ExpR
SinISinR
AHLs
ExpR
nutrient limitation
SinISinR
AHLs
AHLsExpR
SinR
AHLs
ExpRAHLs
intermediate stagelog growthlog growthstat. phase & lag phase
