Control #A A5 2 wk p.i. Brain Spleen A2 12 wk p.i. Sakuma et al., Supplementary Fig. S1 Fig. S1...
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Control #A A5 2 wk p.i. Brain Spleen A2 12 wk p.i. Sakuma et al., Supplementary Fig. S1 Fig. S1 Immunostaining of brain and spleen sections with goat anti-gp70/gp30 antibody (green). Nuclei were counterstained with DAPI (blue). Immunostaining images of XMRV-infected animals at 2 wk and 12 wk p.i. were compared with those of the control mouse #A.
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Transcript of Control #A A5 2 wk p.i. Brain Spleen A2 12 wk p.i. Sakuma et al., Supplementary Fig. S1 Fig. S1...
Control #AA5
2 wk p.i.
Bra
inS
ple
en
A212 wk p.i.
Sakuma et al., Supplementary Fig. S1
Fig. S1 Immunostaining of brain and spleen sections with goat anti-gp70/gp30 antibody (green). Nuclei were counterstained with DAPI (blue). Immunostaining images of XMRV-infected animals at 2 wk and 12 wk p.i. were compared with those of the control mouse #A.
N1 N2Control
CD
3/C
D11
bC
D19
CD
3/G
r-1
A2
Sakuma et al., Supplementary Fig. S2
Fig. S2 Immunohistochemical analyses of immune cells in spleens of XMRV-infected and uninfected mice. Spleen sections were analyzed with anti-CD3, CD11b, CD19, and Gr-1 antibodies to detect T cells, macrophages, B cells, and neutrophils, respectively. Representative immunostaining results for control mice and XMRV infected mice (A2, N1, N2) were shown. Nuclei were counterstained with DAPI (blue).
Sakuma et al., Supplementary Table 1
a WBC, LYM, NON, GRA, RBC, HGB, HCT, MCV, MCH, MCHC, and PLT represents white blood cell, lymphocyte, monocyte, granulocyte, red blood cell, hemoglobin, hematocrit, mean corpuscular volume, mean corpuscular hemoglobin, mean corpuscular hemoglobin concentration, and platelet, respectively.b Numbers outside of the 95% reference range are highlighted.
C1 C2 C3 C4 C5 C6 C7 C8 C9 C10 C11 C12(wk 30) (wk 30) (wk 28) (wk 28) (wk 11) (wk 11) (wk 11) (wk 11) (wk 7) (wk 7) (wk 7) (wk 7)
WBCa 6.17 7.34 6.93 6.51 7.05 8.63 4.81 4.78 6.21 6.23 5.9 7.06
LYM 4.77 5.51 4.47 4.65 5.15 5.09 3.61 3.35b 4.8 4.75 4.31 5.07
MON 0.17 0.15 0.12 0.08 0.19 0.21 0.28 0.22 0.04 0.07 0.29 0.2
GRA 1.23 1.68 2.34 1.78 1.71 3.32 0.92 1.2 1.37 1.41 1.3 1.78
RBC 10.95 10.95 10.59 10.85 8.39 10.65 10.07 10.71 10.75 10.93 10.54 11.48
HGB 17.2 17.4 17.2 16.9 13.4 17.6 15.7 16.9 15.7 17.7 17.2 17.7
HCT 47.14 46.89 47.1 46.33 35.17 45.25 41.95 45.39 42.37 46.75 46.51 47.53
MCV 43 43 44 43 42 42 42 42 39 43 44 41
MCH 15.7 15.9 16.2 15.5 16.0 16.5 15.6 15.8 14.6 16.2 16.3 15.4
MCHC 36.4 37.0 36.4 36.4 38.1 38.8 37.4 37.3 37.1 37.9 37.0 37.2
PLT 626 721 175 344 688 703 885 826 814 580 622 737
Average ± 1.96 STDV
4.4-8.6
3.4-5.9
0.01-0.32
0.4-2.9
9.1-12.114.3-19.2
38-52
40-45
14.8-16.8
35.8-38.7
244-1042
Supplementary Table 1. Summary of CBC test results for uninfected Mus pahari
