Consult Webinar

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  • Bio-Identical HormoneReplacementJulie Gorman, PharmDDLisa Haas, PharmDKristen Riddle, PharmDBecca Mitchell, PharmDPamela Sampson, Pharmacy Technician

  • The TriadPHYSICIANPHARMACISTPATIENT

  • What is Natural?Bio-identical hormones that are derived from plants

    Bio-Identical: Hormones that are identical to those made in the human bodySame exact chemical structure as hormones produced by our bodiesPlant-Derived: Chemically processed from precursors found in yam or soy plants

  • What is Synthetic?Patented, Conventional, or Artificial

    Usually not found in nature, at least not in humans

    Chemically altered from human hormone

    Not identical in structure or activity to the natural hormones they emulate

  • Progesterone vs ProgestinBio-Identical, HumanIncreases fertilitySynthetic analogContraceptiveMedroxyprogesterone acetate (Provera)

  • Life StagesPRE-MENOPAUSEBegins with first menstrual periodMonthly fluctuations of LH, FSH, estrogens & progesteroneMost common problem is PMSNeurotransmitter profile affected by fluctuating hormones (endorphin, serotonin)Often successfully treated with stress reduction, diet, exerciseTreated with progesterone, SSRIs

  • Life StagesPERI-MENOPAUSETime between onset of changes in hormonal secretions and onset of menopauseFluctuating hormone secretions due to intermixed normal & abnormal cyclesSometimes referred to as period of Estrogen Dominance

    MENOPAUSETermination of menstrual periodsDefined as missing 12 consecutive periodsSurgical hysterectomy

  • Signs & Symptoms of Hormone ImbalanceDepressionFatiguePoor concentrationHot flashesBreast tendernessInsomniaAnxietyPainful mensesIrregular bleedingIrritabilityHair lossFibroidsWater retentionCholestasisWeight gainDecreased libidoBreast & uterine cancer

  • Estrogen Benefits & RisksBenefits of Adequate EstrogenIncrease metabolismIncrease insulin sensitivityMaintain muscle massImprove sleep qualityPrevent AlzheimersReduce cataractsReduces overall risk of heart disease by 40-50%Numerous cardiovascular benefitsMaintain collagen in skinDecrease blood pressureMaintain memoryImproves concentrationMaintain bone densityIncreases energy & sexual interestDecreases wrinkles

    Risks of Excess EstrogenDepressionFluid retentionHeadachesPoor sleepIrritability/mood swingsFatigueIncreased risk of auto-immune diseasesWeight gainIncreased risk of breast & uterine cancer

  • Promoting Healthy Estrogen LevelsConservative, customized dosingDiet high in grains & fiberModerate exerciseStress reductionVitamins B2, B6, B12, Folic AcidOmega-3 fatty acids (fish oil)Healthy body mass index (BMI)

  • Progesterone & TestosteroneProgesteroneHelps balance estrogenImproves sleepNatural calming effectLowers high blood pressureHelps the body use & eliminate fatsLowers cholesterolIncreases metabolismNatural diureticNatural antidepressantAntiinflammatoryStimulates new bone productionEnhances action of thyroid hormonesImproves libido

    TestosteroneIncreases sexual interestIncreases sense of emotional well-beingIncreases muscle mass & strengthHelps maintain memoryHelps skin from saggingDecreases excess body fatHelps maintain bone strength

    Natural Ways to Improve LibidoDecrease calorie & increase protein intakeExerciseGet enough sleepLose weightReduce stress

  • CortisolOnly hormone that increases with ageMade by the adrenal glands (on top of the kidneys)Supposed to briefly increase during times of stressAdrenaline is the run from a bear stress hormone while cortisol is our stuck in traffic stress hormoneShould start highest in the morning and gradually fall throughout the day

    Functions:Balances blood sugarWeight controlImmune system responseStress reaction Sleep

  • Cortisol ImbalanceHigh CortisolFatigueIrritabilityInsomniaSugar cravings & binge eatingIncreased osteoporosis riskDecreased immune systemLow energyNight sweatsIncreased cholesterolInsulin resistanceThin skinMuscle weaknessEasy bruisingWeight gain around the middleImpaired thyroid functionLow Cortisol (Adrenal Fatigue)FatigueLow blood pressureInsomniaDecreased sexual interestDecreased immunityEmotional paralysisAllergiesUnresponsive hypothyroidism (does not respond to treatment)Feeling of being overwhelmedEmotional imbalancesLack of motivationDigestive problems

  • Balance is Key!THYROIDCORTISOLSEX HORMONES

  • Our GoalsSymptom improvement within 2 monthsImproved overall health & quality of lifeHormone balance through:Conservative dosingAdequate, appropriate nutritionRegular exerciseStress management

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