Computer Aided Detection-Exploring New Realms of Clinical Applications
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Transcript of Computer Aided Detection-Exploring New Realms of Clinical Applications
Computer Aided Detection – Exploring New Realms of Clinical Applications
Kaavya Karunanithi, Research Associate
HealthcareHealthcare
September 8, 2011
Evaluation of
Implementation of Strategies
Today’s Presenter: Kaavya Karunanithi
Functional Expertise•Market research in the Medical Imaging sector•Competitive analysis and benchmarking skills•3 years of research experience in various sectors of biotechnology, biomedical and biomaterials engineering
Industry Expertise•Knowledge of various Medical Imaging and devices sectors in the European market•Authored various market insights and research services in the medical imaging sector
What I bring to the team•Novel outlook at the market perspectives
2
Generation of Opportunities & Strategies
Evaluation of Opportunities & Strategies•Technical expertise and skilled analytics
Career highlights•Co-authored articles in international peer reviewed journals•Worked on cloning and characterization of BCAS and OCIAD genes in Indian Institute of Science •Worked on cloning and characterization of HCN 4 genes at Dr KM Cherian tissue engineering institute•Worked on design and optimization of coils for cerebral aneurysms using computational fluid dynamics principles at Australian School of Advanced medicine•Member of Association of Professional Engineers, Scientists and Managers, Australia (APESMA)
Education•Masters in Biomedical engineering, University of Sydney, Sydney, Australia•Bachelor of Biotechnology, SRM university, India•Business English Communication (Cambridge University)- certified
KAAVYA KARUNANITHIResearch Associate-Healthcare
Frost & Sullivan, EuropeChennai, India
Focus Points
� Market overview
� Supply chain analysis
� Industry challenges
� Market drivers and restraints
� Market forecasts
3
� Market forecasts
� Geographic trends
� Competitive analysis
� Strategic recommendations
Market Overview
CAD software constitutes a set of algorithms, which
by using the technique of pattern recognition, aides
the radiologist in detecting potentially diseased
•CAD has long since left behind its branding as a
supplement tool and has now widened its application
areas. It is now a valuable tool for detection and
diagnosis of various types of cancer.
This European CAD market is in its early growth stage
and is highly dependent on its corresponding imaging
modality market dynamics for its market penetration.
4
the radiologist in detecting potentially diseased
regions and lesions. This is done by using clinical
images obtained from various imaging modalities as
a platform.
With increasing use of CAD software for various
diagnostic applications of oncology, the market can be
described as highly specialized, competitive and
dynamic with considerable growth potential.
A unique feature of CAD market is the OEMs that
incorporate CAD solutions into their modalities
have a huge role to play in determining the market
dynamic parameters, along with CAD suppliers.
Market Scope
Product segmentation Geographic scope
CAD
Breast CAD
Chest CAD
GermanyUnited Kingdom
5
Chest CAD
Colon CAD
Prostate CAD
Liver CAD
Bone CAD
Benelux France
Spain
Italy
Scandinavia
Technology and Market Trends
• The European CAD market will have increasing growth
rates as the need for digitization and highly automated
integrated workflow will increase with widening clinical
applications of CAD and development of multimodal
imaging solutions.
• The commercialization of investigational CAD
applications will lead to new entries in the market
thereby expanding the product portfolio available in
terms of technologically superior variants such as Medic
RISDemographic
reports
Imaging Modality
6
terms of technologically superior variants such as Medic
sight's colon CAD 4.0. The increased competition may
also result in price fluctuation.
• There is a need for large scale clinical studies validating
the competence of CAD products. This will aid in its
widespread penetration throughout Europe.
• The market is expected to grow steadily during the
forecast period. Newer segments like chest, colon,
prostate, liver and bone will have an increased percent
revenue contribution to the total CAD market of Europe.
CAD
Diagnostic Imaging
workstation
Image Storage
Online Image
storage
Off line Data recovery back up
Source: Frost & Sullivan
Market Adoption Trends
0.0
0.5
1.0
1.5
2.0
2.5
3.0
3.5
United Germany France Spain Italy
ScandinaBenelux
•From the graphical representation we
can see that there has been a steady rise
in the number of cancer incidences
reported for the past 5 years.
•Germany, France, Spain and Italy has
the highest compound annual growth
rate of cancer occurrence.
•Breast, prostrate and colon cancer
along with coronary artery disease acts
7
CAGR of cancer incidence for
2005-2010 in %
1.3 1.6 2.9 2.6 3.3 0.1 1.6
United
KingdomGermany France Spain Italy
Scandina
via Benelux
Compound annual growth rate of reported cancer incidences (Europe), 2005-2010
along with coronary artery disease acts
as the single largest cause of death in
Europe according to the report published
by European Union.
•This has in turn increased the need for
early detection of the mentioned
conditions by using various
prognostic/diagnostic measures like CT,
MRI and US scans, which incorporate
CAD modality within them.Source: Frost & Sullivan
Healthcare Expenditure Overview - Europe
BeneluxScandinavia
Spain
Italy
FranceGermany
United Kingdom
0.0
10,000.0
20,000.0
30,000.0
40,000.0
50,000.0
60,000.0•A number of large scale multi
centric clinical trials are being held
for validating the efficiency of
established CAD regimes namely,
breast and colon CAD.
•The results of these studies
indicate a 15 to 40 percent
reduction in the cancer mortality
rate.
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0.0
0.0 1,000.0 2,000.0 3,000.0 4,000.0 5,000.0 6,000.0
H ealthcare expenditure per capita $
rate.
•Additional short term clinical
studies on newer clinical
applications of CAD including
bone, prostate and liver offer
promising results which imply
CAD as a robust diagnostic tool in
the early detection of cancer.
Due to increased prevalence of cancer, European countries have and are continuously increasing their percent GDP spent on cancer prevention and regulation.
This is evident from the healthcare expenditure per capita data given above.
Source: Frost & Sullivan
Geographic Trends
• Numerous nationwide screening
programs for detection of breast cancer
using digital mammography techniques
which incorporate CAD along with
colon cancer screening programs are
already in place in most of the
European countries like the United
Kingdom, Germany, France etc.
• NHS has recently introduced an
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• NHS has recently introduced an
informed choice, Prostate cancer risk
management program based on the
results of the European Randomized
Screening for Prostate Cancer (ERSPC)
study.
• Informed choice programs for low dose
helical CT scanning for lung cancer has
been introduced in France and Benelux.
CAD Manufacturer
Alliances
rers
Alliances with OEM Manufactu
rers
Distributors
Direct Sales/Web services
•The supply chain for the CAD industry in Europe is
versatile in nature.
•There are absolute standalone workstations or CAD
integrated with the imaging modality. A fair share of market
participants have started offering web-based services of
CAD solution.
•CAD solutions of non Europe-based manufacturers is sold
through regional distributors. Some of the CAD
manufacturers like iCAD and EDDA technologies have
strategic alliances with the OEMs, which involve in selling
the third party CAD software as a part of their imaging
modality.
•The larger OEMs like GE and Siemens also integrate their in
Supply Chain Analysis
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,
End Users (Hospitals
and Clinics)
•The larger OEMs like GE and Siemens also integrate their in
house CAD algorithms into their CT and MRI scanner.
•The newer trend of web-based services and pay-per-use
model is gaining acceptance with the users as they get to
have a say in the customized payment model.
•In future, we can expect an increased preference for this
mode of distribution. At the end of forecast period, this shift
will be evident. Nevertheless the standard procedure of sales
through software distributors and integrated workstations
will also be practiced. Source: Frost & Sullivan
Ambiguous reimbursement patterns affect the adoption rate of the technology
Need for large-scale clinical studies validating the efficiency of CAD procedures
Industry Challenges
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Industry Challenges
Ambiguous reimbursement patterns affect the adoption rate of the technology
Dynamic market state, in terms of technology and competition, demands
continuous evolution of its products
Inhibition of radiologists against CAD utilization and shortage of resources and
trained personnel
Market Drivers and Restraints
Very High Growth Impact
Increased prevalence and
awareness of
cancer and coronary artery
disease
High Growth Impact
Commercialization
of investigational
CAD areas
Growth and performance of CAD
software manufacturers have greater
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Low GrowthImpact
Medium GrowthImpact
High cost of solution
and a highly
competitive market
induces price war
Urgent need for a
high number of white
papers and
publications
validating efficiency
Transition to Electronic
Health Records (EHR)
dependence on larger OEMs
DRIVER RESTRAINTSource: Frost & Sullivan
Product Lifecycle Analysis
Chest CAD
Early majorityInnovators Early adopters Late majority
Ad
op
tio
n
Laggards
Breast CAD
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Colon CAD
Bone CAD
Prostate CAD
Time
Ad
op
tio
n
Source: Frost & Sullivan
Liver CAD
Market Parameters and Forecasts
Average price per unit
$50,000-$150,000
Number of competitors
(2010)
17+
7 9 . 0 %
14 . 4 %
3 . 5 %1. 6 %1. 0 %0 . 5 % Per cent revenue
contribution by segments
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Source: Frost & Sullivan
R&D Spend as a Percent of Market Revenue
6%Marketing Spend as a Percent of Market Revenue
4.5%
$150,000
2010 2017
$234.8 M
$822.7 M
CAGR (2010-2017) 20.7%
Breast Chest Colon
Prostrate Liver Bone
Competitive Analysis
Tier 1Competitive Factors
-Product portfolio width
-Geographic presence
-Price
•Siemens
•Philips
•GE
•iCAD
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Tier 2 & 3
-Price
-Business Model
- Vendor Relationship
•Medicsight
•Sectra
•Riverain
medical
•Medipattern
•Median
•EDDA
•im3D
•Confirm
Widening the scope of clinical applications to all areas of oncology and cardiology is a key technological trend.
Chest CAD solutions is likely to have exponential growth in the next 3-4 years. Prostate CAD
will also be a high growth rate segment. Heavy marketing of bone CAD and slow growth of
colon and liver CAD will be observed.
Strategic Recommendations
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CONCLUDING
POINTS
Need for digitization and automated integrated workflow processes will act as major drivers for
market. Large scale, long-term clinical studies and white papers will be needed to prove potency in
CAD’s newer segments.
Germany, UK and France are big markets for chest and prostate CAD. Scandinavia and Benelux will have a
high adoption rate in terms of emerging segments of CAD; and Spain and Italy will continue to contribute to
colon CAD’s revenue. Breast CAD will have a uniform penetration rate throughout Europe.
Mammo CAD is likely to reach a steady growth rate and will reach the pinnacle in terms of
adoption, whereas breast MRI and ultrasound CAD is here to grow.
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For Additional Information
Katja Feick
Corporate Communications
Healthcare
0049 (0) 69 7703343
Noel Anderson
European Vice President
New Business Development
+44 (0)207 343 8389
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Kaavya KarunanithiResearch Associate - Medical Technologies Healthcare+91 44 6160 [email protected]