Company Presentation

17 YEARS OF HISTORY

FROM 2000 ONWARDS

FROM CONSULTING TO RESEARCH…

FROM RESEARCH TO MARKET.…

INNOVATIVE, YOUNG AND CUTTING EDGE

OUR JOURNEY

THROUGH INNOVATION

IN LIFE SCIENCES

IMS is recognized top player in Italian Healthcare System

Sanipedia is founded. (Exploitationof research results)

Strategic Agreement IMS-Ernst & YoungFor Healthcare Advisory Unit

5 new companies are foundedproviding high level scientific services:

genomics, cell assays, nutraceutics, bioinformatics, etc..)

3 Innovative Startups

are founded

New Innovative Startup initiatives are

being fostered

Set up of Grant Office for European Research Projects

4 Research Projects are granted by EC:

32 mln €

11 Research Project are granted by EC & Italian Institutions:

26 mln €

Sanipedia Business Nursery isset up for the exploitation of veryearly stage research results and

innovative ideas

IMS is founded. (Healthcare

Advisoring and Management)

"Garden of Ideas" set up is ongoing

OUR HISTORY

The Mission

Life science research often leads to bright novel ideas.Unfortunately, inventors struggle to turn those ideas into market product/services due to:

• Lack of managerial skills• Lack of business development expertise• Lack of funds

The Need

To support researchers and young entrepreneursat the very early stage of their project,

when the ideas/initiative are too immature to attract financial partners, providing managerial, scientific, niche market and fund raising expertise to set up and validate the business idea

/initiative

The Vision

To set up a leading international hubfor nurturing innovative ideas and very early stage initiatives in Life Sciences, with the aim of making them self-sustainable

and to facilitate their scientific and market future developments

Drug DiscoveryLead

OptimizationIn Vitro In Vivo Phase I Phase II Phase III Market

ProductService

Basic Research

AppliedResearch

PoCBusiness

Plan

Prototype Prototype Prototype ProductRevenueGrowthService

DefinitionService

EngineeringService

ProductionService

Introduction

Funding ResearchGrants

Development Grant

Friends&

Family

AngelInvestors

Early Stage Venture Capital

Venture Capital

Private Equity

IPOM&A

+ €

0 €

- €

ADVISORYGrant OfficeProject Design and Management Clinical Studies SupportHealthcare ConsultingManagement Advisory

BUSINESS NURSERYScouting of New IdeasCoaching and TutorshipExperimental ValidationNew Initiative StartupExploitation of Ideas

SCIENTIFIC SERVICESIn Vitro / In Vivo StudiesGenomic StudiesIn Silico ActivitiesBioinformatics and BiostatisticsClinical Studies

Action Area

time

Death Valley

Our Business Model

Partnership

Wet Labs

Bioinformatics Lab

Genomics Lab Cell Lab

SequencingTrascriptomics

Molecular Biology

In vitroIn vivoEx vivo

Scientific & Technological

Platforms

Dry Lab

Analysis - Phenotype- Genotype- Sequencing

Bioinformatics- Clinical data- «omic» data- Data mining

Scientific & Managerial Services

ClinicalStudies

Grant OfficeGrant design and applicationGrant Management Technical-Scientific coordination

SpecializedServices

Scientific Office: «one-stop shop»Statistical & epidemiological serv.

Nursery Services

Administrative

Business Development

Scouting, incubation & growthB. concept, model & planMarket Analysis & plan

ManagementOrganization & operationsPlanning & reporting

AdministrativeFinancialHR Management

Study ManagementData Management & AnalysisClinical Monitor

Our Organizational Structure

08/02/2017

Sanipedia's Network

Advisory

2015 – Sanipedia

Sanipedia offers advisory services in several areas of Health and Life Sciences including grant management, support for clinical studies and Healthcare advisory.

Grant

OfficeFund Raising and Grant

Management

Management Service Grant Identification Proposal Coordination Proposal Submission Negotiation Project Management Office

Technical-Scientific Services Project Design Project Writing Specific Content Contribution Project Technical-Scientific

Coordination

Clinical

StudiesSupport for Observational and

Interventional Studies

Study Management Clinical Protocol Preparation CRF Development Clinical Monitoring Adverse Events management Data Management Statistical Data Analysis Final Reports Preparation

Healthcare

AdvisoryStrategic, Executive and Managerial Support for Healthcare Institutions

Strategic Plans BPR Activities Management of Innovative

Projects Health ICT Project: Planning

and Management

Advisory

Business Nursery

Experimentalvalidation

Support to fund raising

Coaching and tutorship

Project management

IP clearance Novelty assessment Market assessment Project planning

Sources of Innovation

AcademiaResearch Centers

ScientistsInnovative SMEs

Scouting Nursering

Industrial Alliances

Business Nursery

Launch

Business Nursery

Pipeline Examples

Research Laboratories

2015 – Sanipedia – Storini C.

Age Related Macular Degeneration Alzheimer's Disease Parkinson's Disease Neuropathic Pain Ischemia Blood Brain Barrier Endothelial Barrier Breast Cancer Dermatosis Psoriasis Immune Cells and Inflammation Multiple Sclerosis …

Biochemistry Morphological

Studies Functional Studies Molecular Biology

NeuroscrinScreening Platform

for neurologicaldiseases

IVND In Vitro

Neurodegenerative Disease Platform

In vitro Services

In Vivo Services MicroTISSUE

Pathology-Specific Platforms

Study of the Microenvironment Mode of Action

Surgical Services Proof of Concepts

Recreating the complexity of a tissue microenvironmentfor more informative drug screening

Cell Laboratory

Definition and Analysis of clinical relevant phenotypes in human and veterinary medicine

Genotyping and Genome Wide Analysis

SNPs characterization and genotype-phenotype association analysis

Pharmacogenomics studies

Gene expression (methylation, miRNA, etc…)

Transcriptomics

Next Generation Sequencing (whole genome, exome analysis, etc…)

Biostatistics and Bioinformatics

Main Strengths Fine control of the entire working process thanks to the multidisciplinary approach and

to the tight collaboration with national and international academic networks. Personalised service offer according to Client’s needs Multidisciplinary area of interest National and international partners collaborations

Genomic Laboratory

ACHIEVEMENTS from 2008

10ENTERPRISES STARTEDwith high technological value, from genomics, to medical, to

agrofood and biotech

>5 Mln €PRIVATE INVESTMENTS

collected for internalinitiatives, generating over

18Mln € in value

up to 20xMULTIPLIERS

obtained from pre-moneyvaluations of internal

initiatives

over 40COLLABORATORS

within a solid, multidisciplinary, passionate and collaborative

team, challenged every day with innovative ideas, with theirpeculiarities and feasibility

58MlnFINANCING

collected at national and international level, for

highly innovative projects

45INTERNATIONAL PARTNERSfrom the biomedical research

world: Universities, public/private Research

Centers, Biotech, Pharma and Researchers