Note: This SOM was revised 23 June 2005; see page 13.

Science Supporting Online Material

Community Proteomics of a Natural Microbial Biofilm Rachna J. Ram, Nathan C. VerBerkmoes, Michael P. Thelen, Gene W. Tyson,

Brett J. Baker, Robert C. Blake II, Manesh Shah, Robert L. Hettich, Jillian F. Banfield 10.1126/science.1109070

Materials and Methods Chemicals and reagents Unless otherwise stated, chemical reagents were obtained from Sigma Chemical Co. (St. Louis, MO). Modified sequencing grade trypsin from Promega (Madison, WI) was used for all protein digestion reactions. The water and acetonitrile used in all sample clean up and HPLC applications was HPLC grade from Burdick & Jackson (Muskegon, MI) and the 98% formic acid used in these applications was purchased from EM Science (Darmstadt, Germany).

Collection of biofilm samples Fig. S1 indicates the sampling locations within the mine, including the pink biofilm collected for community genome analysis (S1). For the present study, several hundred grams of biofilm suspension were collected from the Richmond mine in January 2004, near the downstream confluence of drifts AB and B (AB-End). A portion was fixed on site (see below); the rest was transported within the mine at ambient temperature and put on dry ice within an hour of collection, transported back to the laboratory, and then stored at –80°C.

Whole-cell rRNA oligonucleotide–based analysis Samples were washed twice with 10 mM phosphate-buffered saline (7 mM NaH2PO4, anhydrous, 3 mM NaH2PO4, and 130 mM NaCl, adjusted to pH 1.2 with H2SO4), fixed overnight with 3 volumes of 4% paraformaldehyde to 1 volume of sample, and stored at –20°C within 8 hours of collection. Hybridizations were performed on fixed samples as previously reported (S2), with incubation at 46°C and washing at 48°C for 15 min. Probe ARC915 (S3) was used for Archaea, probe LF655 (S3) for all Leptospirillum groups, LF1253 (S4) for Leptospirillum group III, and EUB338 (S5) were used to visualize all bacterial members of the community.

Preparation of biofilm protein fractions for mass spectrometry To prepare protein fractions, a sample of biofilm containing around 1010 cells was thawed and processed at 4°C. Cells were suspended in 3 volumes H2SO4 (pH 1.1), washed by rotation for 30 min, and recovered by centrifugation at 12,000g for 20 min. This wash was repeated once by resuspending the cell pellet in the same volume of sulfuric acid solution, and the two reddish-yellow supernatants were combined to form the extracellular fraction. Since the extracellular fraction was collected after treatment of the biofilm by cold osmotic shock it is possibly enriched in both periplasmic and extracellular proteins (S6). Cells were resuspended in 20 ml 0.1 M sodium acetate (pH 5.0), placed on ice, and lysed by sonication by using a micro-probe at high power with 30-s pulses for 10 min. The suspension was centrifuged at 5,000g for 20 min, and the

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pellet containing cells and debris was reextracted with an additional 20 ml of buffer. The combined supernatants constituted the cellular fraction. Centrifugation of the cellular fraction at 100,000g for 1 hour yielded a clear, yellowish supernatant enriched in soluble, cytoplasmic proteins. Fractions enriched for extracellular, whole cellular, and soluble proteins were precipitated with ice-cold 10% trichloroacetic acid, and the pellets were rinsed with cold methanol and air-dried.

For membrane fractions, cells from an equivalent quantity of biofilm were washed as described above, resuspended, and split into two tubes. Cells recovered by centrifugation were then resuspended into 12 ml either H2SO4 (pH 1.1) (for membrane sample “M1”), or 20 mM Tris-SO4 (pH 8.0) (for the membrane sample “M2”). These were placed on ice and lysed by sonication as described above. After centrifugation, supernatants were diluted with 40 ml of either H2SO4 (pH 1.1) (“M1”) or 0.1M sodium carbonate (pH 11.0) (“M2”) and mixed by rotation for 30 min at 4°C. These were centrifuged at 6000g to remove precipitates, and the supernatants were centrifuged at 100,000g for 1 hour. The membrane pellets were washed once by resuspension in the appropriate buffer, the ultracentrifugation step was repeated, and each membrane pellet was resuspended in 1 ml of the same buffer. Each of the fractions was denatured and reduced in 6 M guanidine-HCl, 10 mM DTT, at 60°C for 1 hour. Samples were diluted 6-fold in 50 mM Tris-HCl/10 mM CaCl2 (pH 7.8), sequencing-grade trypsin was added at ~1:100 (w/w), and digestions were performed with gentle shaking at 37°C for 18 hours. This was followed by a second addition of trypsin at 1:100 and an additional 5-hour incubation (S7). The samples were then treated with 20 mM DTT for 1 hour at 37°C as a final reduction step, and immediately de-salted by using Sep-Pak Plus C18 (Waters, Milford, MA). All samples were concentrated and solvent exchanged into 0.1% formic acid in water by centrifugal evaporation to ~10 µg/µl starting material, filtered, aliquoted, and frozen at –80°C until LC-MS/MS analysis.

Mass spectrometry analysis We combined two proteomic datasets (identified as LCQ and LTQ) that were generated by triplicate analyses of each fraction. The LCQ dataset was generated on a liquid chromatography electrospray 3-dimensional quadrupole ion trap mass spectrometer (Thermo Finnigan, San Jose, CA), whereas the LTQ dataset was generated on a liquid chromatography electrospray two-dimensional (2D) linear ion trap mass spectrometer (Thermo Finnigan) (see experimental details below). Both analyses used an identical 2D nano-LC tandem mass spectrometry (MS/MS) system with a split-phase column (S8).

For the LCQ dataset, an Ultimate HPLC (LC Packings, a division of Dionex, San Francisco, CA) was used; for the LTQ dataset, a Surveyor HPLC (Thermo Finnigan) was used. Each pump provided a flow rate of ~100 µl/min, which was split pre-column to provide an approximate flow of ~200–300 µl/min at the nanospray tip. The split-phase columns were constructed as follows: the back column was packed with approximately 3.5 cm of strong cation-exchange material (Luna SCX 5 µm 100A Phenomenex, Torrance, CA) into a 100 µm fused silica via a pressure cell followed by 3.5 cm of C18 reverse phase (RP) material (Aqua C18 5 µm 200A Phenomenex). The sample was then loaded off-line onto the dual phase column. For all samples, ~200–500 µg of protein was

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loaded onto the back dual phase column. The loaded RP-SCX column was then positioned on the instrument behind a ~15 cm C18 RP column (Jupiter C18 5 µm 300A Phenomenex) also packed via pressure cell into a Pico Frit tip (100 µm with 15 µm tip New Objective, Woburn, MA). The entire column system was positioned directly in the nanospray source (Thermo Finnigan) on either the LCQ or LTQ mass spectrometers.

All samples were analyzed via a 24-hour 12-step 2D analysis consisting of increasing concentration (0–500 mM) salt pulses of ammonium acetate followed by 2-hour reverse phase gradients from 100% aqueous solvent (95% H2O/ 5% ACN/ 0.1% formic acid) to 50% organic solvent (30% H2O/ 70% ACN/ 0.1% formic acid). During the entire chromatographic processes, the LCQ or LTQ mass spectrometers operated in a data-dependent MS/MS mode detailed below. The chromatographic methods and HPLC columns were virtually identical for all analyses. The LC-MS system was fully automated and under direct control of the Xcalibur software system (Thermo Finnigan).

The LCQ and LTQ mass spectrometers were both operated with the following parameters: nanospray voltage (2.4 kV), heated capillary temp 200°C, full scan m/z range (400–1700). The LCQ data–dependent MS/MS mode was set up with the following parameters: 4 MS/MS spectra for every full scan, 5 microscans averaged for full scans and MS/MS scans, 5 m/z isolation widths for MS/MS isolations and 35% collision energy for collision-induced dissociation. The LTQ data–dependent MS/MS mode was set up with the following parameters: 5 MS/MS spectra for every full scan, 2 microscans averaged for full scans and MS/MS scans, 3 m/z isolation widths for MS/MS isolations and 35% collision energy for collision-induced dissociation. To prevent repetitive analysis of the same abundant peptides, dynamic exclusion was enabled with a repeat count of 1 and an exclusion duration of 1 min on the LCQ and 3 min on the LTQ. All samples (5 biofilm fractions) were analyzed in triplicate on the LCQ with a single m/z range. In addition, the NaCO3–treated membranes (M1) and the whole cell fraction were analyzed with a single 3 m/z range experiment which consisted of 3 individual 24-hour 2D analyses with three segmented m/z ranges (400–900, 850–1300, 1200–1700) on the LCQ. All samples (5 biofilm fractions) were analyzed in triplicate on the LTQ with a single m/z range except the crude soluble fraction, which was analyzed a single time because of lack of available sample.

Proteome bioinformatics The near-complete composite genomes of Leptospirillum group II and Ferroplasma type II and partial composite genomes of Leptospirillum group III and “G-plasma” were previously reconstructed by using DNA extracted from an environmental sample (S1). A partial environmentally derived Ferroplasma type I composite genome is also available (S1), in addition to a complete genome of the closely related F. acidarmanus isolate (S9). In the case of Leptospirillum group II, we improved the initial assembly to yield 89 genome fragments (scaffolds), which were manually annotated. In a few cases, scaffolds were redistributed between organism types based on assembly and di-, tri-, and tetranucleotide frequencies (S10). Although a single amino acid substitution can prevent peptide matching, the most abundant strains are likely to be similar enough to those in the previously characterized biofilm (S1, S9) to permit confident protein detection.

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Five protein databases were used for this study, and each can be found at (http://compbio.ornl.gov/biofilm_amd/databases/). The first database (Biofilm_db1) contained all predicted proteins, based on the community genomic analysis (S1) plus the Ferroplasma acidarmanus fer1 isolate genome (S9). This database contained 12,148 entries and was the primary database used in all data analyses of the LCQ and LTQ datasets. A subset of LCQ and LTQ data was searched against two alternative databases. Biofilm_db2 was created by adding to Biofilm_db1 all proteins ≥100 amino acids encoded in regions of hypothetical genes after six-frame translation and consideration of alternative start and stop sites, resulting in 15,646 protein entries. Biofilm_db3 was created by adding Shewanella oneidensis MR-1, Rhodopseudomonas palustris CGA009, Escherichia coli K-12, and Saccharomyces cerevisiae public protein databases to Biofilm_db1. The purpose of this database search was to determine the level of false-positive identifications by using microbial species known not to be in the sample. A subset of the LCQ data was searched against a database containing genomes from most sequenced microbes and two plant species in addition to the Biofilm_db1. This database contained sequences from >200 microbes and two plants. The AMD Biofilm_db1 database was attached to this database to give a final database which contained 978,849 protein entries (Biofilm_db1_Large). The purpose of this database search was to determine the potential to differentiate the AMD community from the rest of microbial genome space and to determine the false-positive level against a very large database. The results from these alternative database searches can be found in the analysis webpage (http://compbio.ornl.gov/biofilm_amd/analysis/). A final database (Biofilm_db1_snps_1) was created from the PCR information discussed in the report. This database was exactly the same as Biofilm_db1 except for two amino acid changes and removal of the N terminus of the protein LeptoII_scaff_14_GENE_20. The new name for this protein is LeptoII_scaff_14_GENE_20_SNP1 in this database. This new database was used for searching the extracellular proteome LTQ data in order to test the hypothesis of two amino acid changes and N-terminal processing of the protein.

All MS/MS spectra from the LCQ and LTQ datasets were searched against the Biofilm_db1 database as discussed in detail below. Results were evaluated based on matching of one or more peptides, two or more peptides, or three or more peptides per protein as discussed below. All datasets, databases, and resulting identifications from this study are available online (see http://compbio.ornl.gov/biofilm_amd/). Directly linkable spectra for all identified peptides also may be downloaded from the Web site, a step toward open-access proteomics results (S11, S12).

For all database searches, MS/MS spectra RAW files were first converted to mzXML format by using the ReAdW software program developed at the Institute for Systems Biology, Seattle, WA (http://www.systemsbiology.org), and available from SourceForge repository at http://sashimi.sourceforge.net. The mzXML is an XML file format specification developed at ISB for complete spectral information contained in Thermo Finnigan RAW files. The individual spectra for each RAW file were extracted from the mzXML file into corresponding DTA files (required as input to SEQUEST) by using another software program from ISB, mzXML2Other. The mzXML2Other program is capable of extracting the spectra into several different formats in support of the prevalent MS search tools like SEQUEST (S13) and MASCOT (S14). The spectra were then searched by using SEQUEST (Thermo Finnigan), with the following parameters:

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enzyme type trypsin; Parent Mass Tolerance, 3.0; Fragment Ion Tolerance, 0.5; up to 4 missed cleavages allowed. Only fully tryptic peptide candidates were searched, non-specific cleavage was ignored because of potential false-positive rates in large databases searched with the SEQUEST algorithm. The output data files were then filtered and sorted with the DTASelect algorithm (S15) by using the following parameters: fully tryptic peptides only, with delCN of at least 0.08 and cross-correlation scores (Xcorrs) of at least 1.8 (+1), 2.5 (+2) and 3.5 (+3). DTASelect files from all proteome fractions analyzed by the LCQ and LTQ can be found in the analysis page (http://compbio.ornl.gov/biofilm_amd/analysis/) under the corresponding dataset. All DTASelect files were filtered by requiring either (i) 1 or more peptides or (ii) 2 or more peptides per protein. Results are available for download in a text format or an html version, where every identified spectrum can be viewed by clicking on the spectral number (first column, labeled by filename). The DTASelect results from all proteome fractions were then compared with the Contrast program (S15). The analysis page contains global contrast files (all the proteome fractions) filtered at 1 or more peptides, 2 or more peptides and 3 or more peptides per protein. The global analysis file filtered at 2 or more peptides per protein from the LCQ dataset and the LTQ dataset were combined to give the final identified protein list that was used to create Tables S1 and S2. The analysis page also contains inter-fraction contrast files (compares multiple runs on same sample with same instrument platform) filtered at 1 or more peptides and 2 or more peptides per protein, as well as pair-wise comparisons (compare replicates runs of different proteome fractions) at 1 or more peptides and 2 or more peptides per protein.

Detection biases can arise owing to differential protein extraction, matrix effects in the ionization processes, and biases in digestion and sample clean up. Nonetheless, sequence coverage, the number of unique peptide hits (number of unique spectra detected per protein), and MS/MS spectral counts (the number of times any peptide is detected from a protein) are all indicators for protein abundance (S16). The distributions of isoelectric points and molecular weights of all detected proteins were similar to those of all proteins predicted from genome data (Fig. S2), indicating that there was no strong sampling or detection bias with this technique.

Determining relative or absolute abundance of individual proteins is a recognized challenge in MS-based proteomics. (S16). We used peptide count, spectral count, and percent coverage to infer the most abundant proteins in each fraction (see http://compbio.ornl.gov/biofilm_amd/supplemental/ for complete listing of identified proteins per proteome run with these three indicators of abundance). All three measures gave generally similar results with good reproducibility.

Peptide sequencing of cyt579 from the AB-end biofilm An aliquot of the extracellular fraction was solubilized by resuspension in standard protein gel electrophoresis loading buffer at pH 6.8, without any reducing agent. To aid resuspension, samples were vortexed for 1 min in the presence of 0.5 mm silica beads (Biospec Products, Inc.). After a 1 min centrifugation at 13,000g, supernatant derived from the equivalent of ~1 ml of packed biofilm (~1010 cells) was loaded into several wells of a 12% acrylamide protein gel. After electrophoresis, one sample lane was transferred to a Sequi-Blot PVDF membrane (Bio-Rad) and stained with Coomassie using the protocol described on the website for the Protein Core facility at Columbia

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University (http://cpmcnet.columbia.edu/dept/protein/). Another sample lane was stained with Coomassie without membrane transfer, and a third sample lane was stained without membrane transfer for heme-containing proteins by using the o-dianisidine method (S17). The gels stained without transfer are shown in Fig. S3. The PVDF-transferred protein corresponding to the heme stained protein was analyzed by the Protein Core facility, by using Edman degradation sequencing.

Recovery of DNA encoding cyt579 from the AB end biofilm Genomic DNA that was recovered from the AB end biofilm by a modified phenol:chloroform extraction method (S18) was used as a template for PCR. PCR was conducted by using primers RR2 (5’-GCGACAGCGGATCCTGCAGAGCTCGATAT TTTGAAA-3’) and RR3 (5’-TCGGGCGCACGGATCCCTAATGCGCGGATGCG ACCCCGAT-3’), and High Fidelity Taq polymerase (Invitrogen), under conditions recommended by the manufacturer (with a 1-min extension time). PCR products were digested with BamHI, cloned into pET15b (Novagen), and sequenced at the U. C. Berkeley DNA Sequencing Facility.

SOM Text: Results Distribution of organisms in the biofilm Using whole-cell rRNA oligonucleotide-based analysis, 872 cells counted from 6 fields of vision had the following distribution among organism types: 83% Leptospirillum group II, 9% Leptospirillum group III, 8% Archaea, and 1% long, rod-shaped bacterial cells likely to be Sulfobacillus. In comparison, the set of confidently detected proteins had the following distribution: 68% Leptospirillum group II, 13% Leptospirillum group III, 17% Archaea, and 2% unassigned bacteria.

Database tests The analysis to test for incorrect ORF calls used a modified database (Biofilm_db2) that included predicted proteins encoded by all six reading frames in the vicinity of all hypothetical genes in Leptospirillum group II. This database was also amended by ORFs for proteins of ≥100 amino acids that were not identified via automated annotation. A subset of LCQ and LTQ data was searched against this alternative database (subset contained 1 run of each fraction from the LCQ and LTQ data sets). Of the 1,438 confidently detected proteins in these fractions, 28 proteins were detected in alternative or overlapping reading frames and two were the result of the manual annotation (Table S2). The addition of these brings the total number of proteins detected in the biofilm to 2,033.

We estimated false-positive rates by comparing the number of unique peptides identified from the AMD database (Biofilm_db1) to unique peptides identified from species not in the AMD sample by using the databases described above. This slightly overestimates the false-positive rate, since peptides which were originally unique to the AMD database can become non-unique as other peptides in the database have the same sequence. A subset of these "false-positives" may correspond to homologs for which we have no genome sequence, yet are present in the biofilm.

Of the 6605 unique peptides identified by LCQ analysis of the five biofilm fractions by using the Biofilm_db3 database, 12% were false-positives. Analysis of the

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5,397 unique peptides that were derived from proteins for which at least two peptides were recovered revealed a false-positive rate of only 2.8%. A similar analysis of the data from the LTQ analysis revealed a false-positive rate of 16% at the one unique peptide level and 6.2% after considering only unique peptides from proteins matched by at least two peptides.

The false-positive search with Biofilm_db1_Large used only the LCQ sub-dataset. A total of 8,273 unique peptides were identified from the LCQ analysis of the five biofilm fractions, 39% of which were false-positives. Of the 4,925 unique peptides derived from proteins for which at least two peptides were recovered, only 4.5% were false-positives. These results clearly indicate why we chose the two peptide filter level. While one peptide data would result in detection of many more proteins, the chance of false-positives is too high to justify this level of filtering.

Purification and characterization of cytochrome579 from Leptospirillum ferriphilum isolate cultures A pure culture of Leptospirillum ferriphilum strain P3A was grown autotrophically on soluble ferrous ions in an apparatus that permitted the in situ electrochemical reduction of the product ferric ions to achieve enhanced yields of the bacteria (S19). The ferrous sulfate medium (S20) was adjusted to pH 1.6. Cells were cultured in a 45-liter vessel for 30 days under an applied current of 30 A with a voltage that varied from 4 to 7 V. This protocol yielded over 100 g of wet cell paste over the 30-day continuous culture period. Cells were harvested by centrifugation, resuspended in 0.001 N H2SO4, and stored frozen at –20°C.

Frozen cells were thawed and collected by centrifugation at 10,000g for 10 min. Visible absorbance spectra of the red supernatant thus obtained indicated the presence of a cytochrome with a Soret absorbance peak at 426 nm in the thawed storage solution. The cells were resuspended in 0.01 N H2SO4 (4 ml/g wet cell paste) and subsequently disrupted by sonic oscillation for 1 min/g wet cell paste at a power output of 125 watts. Care was taken to maintain the temperature of the solution below 7°C. Centrifugation of the sonicate at 10,000g for 10 min yielded a red pellet and a cloudy red supernatant. The pellet was resuspended in 0.01 N H2SO4 (1.5 ml/g original wet cell paste) and centrifuged as described above. All three red supernatants were combined and subjected to ammonium sulfate precipitation. The bulk of the red cytochrome precipitated between 45% and 95% saturated ammonium sulfate. A red pellet was obtained by centrifugation of the 95%-saturated solution for 20 min at 20,000g. The pellet was dissolved in, and dialyzed against, 0.01 M sodium acetate (pH 5.5). The preparation of red cytochrome was then applied to a column of carboxymethylcellulose equilibrated and developed with the same acetate buffer. A yellow-green cytochrome with an α-absorbance band at 579 nm (Soret peak at 441 nm) eluted from the column in the void volume. This cytochrome exhibited a single band at an apparent molecular mass of around 16,000 daltons when analyzed by standard sodium dodecyl sulfate-polyacrylamide electrophoresis. Oxidation of this purified protein yielded a red cytochrome whose visible absorbance spectrum was identical to that of the red cytochrome preparation that was applied to the column. The source and identity of the reducing equivalents in the carboxymethylcellulose column were not determined.

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Amino terminal microsequencing of the purified red cytochrome was accomplished as described previously (S21).

Purified cyt579 was redox-active with soluble iron at pH 2.0. The absorbance spectra of the oxidized and ferrous iron-reduced cyt579 are presented in Fig. S4. The Soret peak of the cytochrome shifted from 426 nm in the oxidized state to 441 nm in the ferrous iron-reduced state. Concomitantly, an absorbance band appeared with a maximum absorbance at 579 nm. While the peak at 441 nm is reminiscent of that of an a-type cytochrome, the peak at 579 is considerably blue-shifted from that anticipated for a typical a cytochrome. Alkaline pyridine hemochrome spectra of the oxidized and reduced cytochromes provided further spectroscopic evidence that the heme group in cyt579 is unusual and not of the typical a, b, or c type (S22).

Ferrous ions are rapidly oxidized by bacteria that respire aerobically on iron. Kinetic studies on intact cells of Leptospirillum species in acidic ferrous sulfate media yielded maximal rates of ferrous iron oxidation of 422 µg of ferrous iron oxidized per minute per mg of protein, with a corresponding KM value for soluble iron of 0.25 mM (S23). If 5% of the total cellular protein expressed by L. ferriphilum is assumed to be cyt579 (S24), then the apparent turnover number for the transfer of electrons from ferrous iron to molecular oxygen by whole cells may be expressed as approximately 40 s–1 per molecule of cyt579 in the cell. Thus in order for cyt579 to serve as the primary initial electron acceptor in the iron-dependent respiratory chain, the apparent rate constant for the ferrous iron-dependent reduction of the cyt579 must be greater than or equal to the overall turnover number for the entire process, 40 s–1. The inset in Fig S4 shows the change in absorbance at 579 nm as a function of time when 8.6 µM cyt579 was rapidly mixed with 60 mM ferrous ions in 0.2 M sulfate at pH 2.0. The increase in absorbance at 579 nm, indicative of reduction of the cytochrome, was described by a single exponential function of time with a pseudo–first-order rate constant of 84 s–1. Further, the ferric iron-dependent oxidation of the reduced cyt579 occurred under the same conditions (60 mM ferric ions, 0.2 M sulfate, pH 2.0) with a pseudo–first-order rate constant of 63 s–1 (S22). If one assumes that the standard reduction potential of soluble iron in 0.2 M sulfate at pH 2.0 is 660 mV (S25), then the apparent standard reduction potential of the cyt579 may be calculated to be around 670 mV by using these kinetic constants and the equation

(RT/F) ln(kox/kred) = EoFe(II)/Fe(III) – Eo

cyt(II)/cyt(III)

where R is the gas constant, T is the absolute temperature, and F is Faraday’s constant.

On the basis of detected proteins, we inferred a possible arrangement of electron transport components associated with Leptospirillum group II (Fig. S5). It has been proposed for other extreme acidophiles that the naturally steep proton gradient across the plasma membrane is counteracted by a large membrane potential in order to prevent the massive pool of protons in the environment from entering unrestricted through the ATP synthase and acidifying the cytoplasm (S26). One possibility is that as oxygen is reduced by the terminal oxidase (a process dependent on iron oxidation), protons in the cytoplasm are consumed, allowing a transient influx of protons through the ATP synthase complex. This influx of protons is coupled to ATP production. Therefore, it is not obvious whether any of the electron transport chain components still pump protons to the periplasm, as in classical neutrophilic transport chains. In this model, quinones are inferred based on

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detection of UbiB, UbiC, and UbiE homologs. Iron oxidation by soluble, acid-stable cyt579 localized in the periplasm is coupled to oxygen reduction and the generation of ATP. Some electrons are siphoned towards producing NADH for use in biosynthetic pathways (arrows pointing to the left in Fig. S5). Expressed proteins related to c-type cytochromes (possibly including cyt551, cyt553, and four other distinct types) could be involved in the production of NADH and/or serve as intermediates in the transfer of electrons from cyt579 to the terminal oxidase complex.

The distribution of isoelectric points for all predicted Leptospirillum group II proteins and proteins enriched in the extracellular fraction (by more than a factor of two relative to other fractions, as determined by sequence coverage) is shown in Fig. S6.

References for Supporting Online Material S1. G. W. Tyson et al., Nature 428, 37 (2004).

S2. P. L. Bond, S. P. Smigra, J. F. Banfield, Appl. Environ. Microbiol. 66, 3842 (2000).

S3. R. I. Amann, W. Ludwig, K. H. Schleifer, Microbiol Rev. 59, 143 (1995).

S4. P. L. Bond, J. F. Banfield, Microbiol. Ecol. 41, 149 (2001).

S5. R. I. Amann, L. Krumholz, D. A. Stahl, J Bacteriol. 172, 762 (1990).

S6. R. C. Willis, C. E. Furlong, J. Biol. Chem. 250, 2574 (1975).

S7. N. C. Verberkmoes et al., J. Proteome Res. 1, 239 (2002).

S8. W. H. McDonald et al., Int J. Mass Spectrom. 219, 245, (2002).

S9. E. E. Allen et al., unpublished data.

S10. G. W. Tyson, unpublished data.

S11. P. G. Pedrioli et al., Nat. Biotech. 22, 1459 (2004).

S12. S. Carr et al., Mol. Cell. Proteomics 3, 531 (2004).

S13. J. K. Eng, A. L. McCormack, J. R. Yates III, J. Am. Mass Spectrom. 5, 976 (1994).

S14. D. N. Perkins, D. J. Pappin, D. M. Creasy, J. S. Cottrell, Electrophoresis 20, 3551

(1999).

S15. D. L. Tabb, W. H. McDonald, J. R. Yates III, J. Proteome Res. 1, 21 (2002).

S16. H. Liu, R. G. Sadygov, J. R. Yates III, Anal. Chem. 76, 4193 (2004).

S17. R. T. Francis, R. R. Becker, Anal Chem 136, 509 (1984).

S18. J. Flanagan, unpublished data.

S19. R. C. Blake II, G. T. Howard, S. McGinness, Appl. Environ. Microbiol. 60, 2704

(1994).

S20. O. H. Tuovinen, D. P. Kelly, Arch. Microbiol. 88, 285 (1973).

S21. M. Ronk, J. E. Shively, E. A. Shute, R. C. Blake II, Biochemistry 30, 9435 (1991).

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Science Supporting Online Material Ram et al., p. 10

S22. R. C. Blake II, unpublished data.

S23. R. C. Blake II, B. Johnson, Environmental Microbe-Metal Interactions, D. R.

Lovley, Ed. (ASM Press, Washington, DC, 2000), pp. 53–78.

S24. R. C. Blake II, E. A. Shute, paper presented at the International Biohydrometallurgy

Symposium ’97 – BIOMINE’97, Australian Mineral Foundation, Glenside,

Australia, 4–6 August 1997.

S25. R. C. Blake II, E. A. Shute, J. Biol. Chem. 262, 14983 (1987).

S26. D. G. Nicholls, S. J. Ferguson, Bioenergetics 3 (Academic Press, London, U. K.,

2002), pp. 147–149.

S27. S. F. Altschul, W. Gish, W. Miller, E. W. Myers, D. J. Lipman, J. Mol. Biol. 215,

403 (1990).

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Figure and Table Legends Fig. S1. Map of biofilm sampling sites within the Richmond Mine, Iron Mountain, near Redding, California.

Fig. S2. Molecular weight (A) and isoelectric point (pI) distributions (B) of all proteins predicted from genomic analysis compared to those confidently detected by proteomic analysis. This analysis is based on the dominant organism populations present in the biofilm: strains closely related to F. acidarmanus, Ferroplasma type II, Leptospirillum group II, Leptospirillum group III, and “G-plasma.” The top panels are results for all proteins predicted in the genomic dataset and the bottom panels are the results for all proteins detected by proteomic analysis.

Fig. S3. Confirmation that cyt579 is an abundant heme-containing protein in the extracellular fraction of the biofilm. A portion of the extracellular fraction was resolved by gel electrophoresis and stained for all proteins with Coomassie (left) and for heme-containing proteins by using o-dianisidine (right). The protein band corresponding to the heme staining portion of the gel was sequenced by Edman degradation, and found to contain cyt579. The migration of molecular weight standards is noted at the far left. Proteins >40 kD were very weakly visible by Coomassie and heme staining relative to the smaller molecular weight proteins that are shown.

Fig. S4. Absorbance profile of purified cyt579 before (stippled line) and after (solid line) reduction by ferrous ions at pH 2.0. The inset shows the change in absorbance at 579 nm as a function of time when the protein is rapidly mixed with ferrous ions at pH 2.0.

Fig. S5. Working model for the electron transport chain of Leptospirillum group II, based on detected proteins. IM and OM schematically indicate the inner and outer membranes, respectively.

Fig. S6. The distribution of isoelectric points (pI) for (A) all predicted Leptospirillum group II proteins and (B) proteins enriched in the extracellular fraction relative to other fractions.

Table S1. Proteins detected in the biofilm fractions. Listed are proteins confidently detected at the two peptide level, categorized by the organisms, scaffolds, and genes from which they are derived. Also shown are putative identities of proteins based on BLASTP (S27) scores, as well as their estimated molecular weights and isoelectric points. The scores for top BLASTP matches are indicated (“top”), as well as the best scores for matches with a confident identification (“identity”). Proteins in grey are encoded by genes that were duplicated in the database either because they were located on the ends of adjoining scaffolds that were originally separated because of strain variation, or because a single gene was previously split into two coding regions. The percent of the protein sequence that is covered by all detected peptides is also indicated, followed by the average percent of the protein sequence covered by peptides in all runs from each biofilm fraction. (M1 and M2 are membrane fractions, E is the extracellular fraction, W is the whole-cell fraction, and S is the cytoplasmic fraction). The LTQ data are presented,

11

Science Supporting Online Material Ram et al., p. 12

except where proteins were only detected in the LCQ analysis (in which case only the LCQ data are presented).

Table S2. Leptospirillum group II ORFs predicted from the community genome dataset. Scaffold and gene numbers are in column B. Where possible, scaffolds were linked via overlap and mate pair information to make mega-scaffolds (numbered in column A). In many cases linkage was possible because several genes at scaffold ends overlapped. Heavy black horizontal bars separate mega-scaffolds and thin black lines indicate scaffold junctions. Locations of tRNAs (purple text on orange bar), transposase type (black), and predicted (green) and detected (red) plasmid- or phage-like genes are shown in column C. Genes for detected unique and conserved hypothetical proteins are highlighted in column D. ORFs residing within the same operon are indicated in column E by light or dark grey boxes. Functional annotations of proteins for which two or more unique peptides were recovered by proteome analysis are in bold and highlighted by cream bars in column F. Red boxes indicate operons containing at least one gene for a detected hypothetical protein (yellow highlight indicates operons consisting entirely of detected predicted hypothetical proteins). COG families are shown in column G (also see Fig. 5). Scaffolds inferred to represent a possible (probably integrated) plasmid or phage are listed separately at the end of the spreadsheet. Abbreviations: hypo unique, unique hypothetical; c hypo, conserved hypothetical.

12

Science Supporting Online Material Ram et al., p. 13

This SOM was updated 23 June 2005. Table S2 has been remade to show all columns; other minor changes have been made.

13

A B

0

500

1000

1500

2000

2500

3000

3500

0

500

1000

1500

2000

2500

3000

3500

0

100

200

300

400

500

0

100

200

300

400

500

600

700

1-3.9 4-4.95-5.9 6-6.9

7-7.98-8.9

9-9.910-10.9

11-14

pI

Num

ber o

f Pro

tein

s

Num

ber o

f Pro

tein

s

Num

ber o

f Pro

tein

s

Num

ber o

f Pro

tein

s

0-10 10-2020-30

30-4040-50

50-6060-70

70-8090-100

80-90100-200

0-10 10-2020-30

30-4040-50

50-6060-70

70-8090-100

80-90100-200

Molecular Weight (kD)

Molecular Weight (kD)

1-3.9 4-4.95-5.9 6-6.9

7-7.98-8.9

9-9.910-10.9

11-14

pI

Coomassie Heme

N-terminal sequenced

36 kD

27 kD

1.5

1.0

0.5

0.0

Ab

sorb

ance

579

400 500 600

Time, ms0 20 40 60

k = 84 s-1

0.00

0.02

0.04

∆ab

sorb

ance

, 579

nm

Wavelength, nm

Co

Fe(II) Fe(I -

NADH NAD+ 2e-

4H + 4e- + O2

2H2OINSIDE CELL

pH 5

IDE CELLpH < 1

Quinones

NAdeh

Cyt b

FeS

cbb3-type oxidase

Comp ex

ATPsynthase

H+

ADPATP

Cyt579Cyt

c'scyt c

OM

IM Complex IV

+

100

200

300

400

500

0 1-3.94-4.9

5-5.96-6.9

7-7.98-8.9

9-9.910-10.9

11-14

1-3.94-4.9

5-5.96-6.9

7-7.98-8.9

9-9.910-10.9

11-14

0

5

10

15

Nu

mb

er o

f Pro

tein

sN

um

ber

of P

rote

ins

A

B

pI

pI

Ram

et a

l. S

uppl

emen

tary

Tab

le 1

"2"=

two

pep.

"2"

=tw

o pe

p. g

rey

= du

plic

ate

prot

ein

top

iden

tity

Tota

l % A

vera

ge %

Seq

uenc

e C

over

age

in E

ach

Frac

tion

LCQ

LTQ

Locu

sId

entit

y of

BLA

ST

mat

chkD

apI

1/e

1/e

Cov

erag

eM1

M2

EW

S2

fer1

_iso

late

.109

4tra

nspo

sase

55

9.3

021

5.1

1.7

2fe

r1_i

sola

te.1

2D

NA

hel

icas

e II

103

5.8

173

173

1.3

0.43

2fe

r1_i

sola

te.1

3D

NA

-rep

air p

rote

in53

865

519.

53.

162

fer1

_iso

late

.158

5ctra

nspo

sase

46

9.3

023

62

2fe

r1_i

sola

te.1

686c

trans

posa

se-li

ke45

9.8

2222

8.2

2.73

2fe

r1_i

sola

te.1

724

cons

erve

d hy

poth

etic

al8

6.6

2831

.310

.43

2fe

r1_i

sola

te.1

739c

trico

rn p

rote

ase

118

5.6

00

2.6

0.86

2fe

r1_i

sola

te.1

824

trans

posa

se

549.

80

144.

81.

62

fer1

_iso

late

.185

6tra

nspo

sase

39

9.7

154

142.

70.

92

fer1

_iso

late

.403

uniq

ue h

ypot

hetic

al37

8.1

3.9

1.3

2fe

r1_i

sola

te.5

93pe

rmea

se o

f the

maj

or fa

cilit

ator

sup

erfa

mily

529.

452

256.

12.

032

fer1

_iso

late

.933

cun

ique

hyp

othe

tical

(sim

ilar t

o A

1AO

H+

ATP

ase

subu

nit H

)13

6.4

44

12.1

8.06

Tota

l = 1

2

2fe

r1_s

caff_

100_

GE

NE

_19

phos

phat

e up

take

regu

lato

r37

5.7

8282

6.5

2.16

2fe

r1_s

caff_

100_

GE

NE

_8co

nser

ved

hypo

thet

ical

195.

441

17.9

17.9

2fe

r1_s

caff_

1049

_GE

NE

_1co

nser

ved

hypo

thet

ical

295.

221

72.

332

fer1

_sca

ff_10

6_G

EN

E_1

4co

byrin

ic a

cid

a,c-

diam

ide

synt

hase

50

8.9

118

118

6.4

2.13

2fe

r1_s

caff_

110_

GE

NE

_17

(143

-15,

110

-17)

val

yl-tR

NA

syn

thet

ase

536.

217

617

63.

51.

162

fer1

_sca

ff_11

06_G

EN

E_1

uniq

ue h

ypot

hetic

al (v

. wea

k si

mila

r to

fer1

)6

4.5

530

.910

.32

2fe

r1_s

caff_

1142

_GE

NE

_2co

nser

ved

hypo

thet

ical

329.

127

16.2

2.86

5.13

2fe

r1_s

caff_

116_

GE

NE

_21

hist

idin

ol-p

hosp

hate

am

inot

rans

fera

se34

5.9

9494

41.

332

fer1

_sca

ff_12

8_G

EN

E_4

FixC

, ele

ctro

n tra

nsfe

r fla

vopr

otei

n-qu

inon

e ox

idor

educ

tase

465.

310

710

76.

22.

062

2fe

r1_s

caff_

128_

GE

NE

_63-

isop

ropy

lmal

ate

dehy

drat

ase

286.

888

514.

41.

462

fer1

_sca

ff_13

6_G

EN

E_3

cons

erve

d hy

poth

etic

al48

9.1

107

5.7

1.9

2fe

r1_s

caff_

136_

GE

NE

_9ur

opor

phyr

in-II

I C-m

ethy

ltran

sfer

ase

485.

260

606.

52.

162

fer1

_sca

ff_14

3_G

EN

E_1

5va

lyl-t

RN

A s

ynth

etas

e (1

43-1

5, 1

10-1

7)56

5.7

173

173

3.4

1.13

2fe

r1_s

caff_

149_

GE

NE

_16

4-am

inob

utyr

ate

amin

otra

nsfe

rase

505.

40

03.

11.

032

fer1

_sca

ff_15

3_G

EN

E_9

elec

tron

trans

fer f

lavo

prot

ein

alph

a an

d be

ta-s

ubun

it67

5.5

00

2.6

2.6

2fe

r1_s

caff_

160_

GE

NE

_8pe

ptid

yl-p

roly

l cis

-tran

s is

omer

ase

305.

269

699.

36.

22

fer1

_sca

ff_16

1_G

EN

E_1

trans

posa

se

299.

281

1117

.517

.52

fer1

_sca

ff_16

4_G

EN

E_9

trans

posa

se

379.

411

624

8.8

8.8

2fe

r1_s

caff_

172_

GE

NE

_10

urac

il-D

NA

gly

cosy

lase

259.

372

724.

11.

362

fer1

_sca

ff_19

0_G

EN

E_8

cyto

chro

me

P45

042

5.9

9696

6.2

2.06

2fe

r1_s

caff_

194_

GE

NE

_3A

TP-d

epen

dent

pro

teas

e Lo

n55

5.9

058

8.1

3.26

1.3

6.7

2fe

r1_s

caff_

197_

GE

NE

_2ce

ll di

visi

on p

rote

in p

elot

a (p

elA

)19

4.8

3614

12.2

4.06

2fe

r1_s

caff_

202_

GE

NE

_4as

para

giny

l-tR

NA

syn

thet

ase

505.

317

817

86.

82.

262

fer1

_sca

ff_20

3_G

EN

E_1

3ar

gini

ne d

eim

inas

e49

5.7

7573

7.2

2.4

22

fer1

_sca

ff_21

8_G

EN

E_1

cons

erve

d hy

poth

etic

al44

5.5

858.

81.

87.

665.

45.

42

fer1

_sca

ff_23

6_G

EN

E_4

mer

curic

redu

ctas

e50

5.5

134

134

3.3

1.1

22

fer1

_sca

ff_24

3_G

EN

E_1

0gl

ycin

e ox

idas

e (d

eam

inat

ing)

475.

712

511

25.

35.

32

fer1

_sca

ff_27

0_G

EN

E_6

glyc

erol

kin

ase

545.

812

812

87

2.33

22

fer1

_sca

ff_27

8_G

EN

E_9

D-g

lyce

ro-D

-man

no-h

epto

se 1

-pho

spha

te k

inas

e 35

5.8

9633

5.8

1.93

5.8

5.8

2fe

r1_s

caff_

299_

GE

NE

_5A

TP-d

epen

dent

pro

teas

e La

646.

30

07.

82.

61.

762

fer1

_sca

ff_29

9_G

EN

E_7

enol

ase

445.

215

815

85

1.66

22

fer1

_sca

ff_29

9_G

EN

E_8

diph

thin

e sy

ntha

se28

4.9

6161

5.6

1.86

3.73

2fe

r1_s

caff_

301_

GE

NE

_6co

nser

ved

hypo

thet

ical

(onl

y fe

r1)

776.

10

4.2

1.4

2fe

r1_s

caff_

308_

GE

NE

_1co

nser

ved

hypo

thet

ical

(onl

y fe

r1)

405.

916

97

2.33

2fe

r1_s

caff_

330_

GE

NE

_4pr

otei

n tra

nsla

tion

initi

atio

n fa

ctor

5B

647

00

7.1

2.36

2fe

r1_s

caff_

330_

GE

NE

_8th

iam

in-p

hosp

hate

pyr

opho

spho

ryla

se23

5.3

5757

3.9

3.9

2fe

r1_s

caff_

34_G

EN

E_3

5eu

kary

otic

pep

tide

chai

n re

leas

e fa

ctor

sub

unit

147

5.2

00

1.7

0.56

2fe

r1_s

caff_

34_G

EN

E_3

7ce

ll di

visi

on c

ycle

pro

tein

48/

AA

A A

TPas

e (3

4-37

, 11-

13)

825.

30

07.

41.

562.

862

fer1

_sca

ff_34

_GE

NE

_42

2-ph

osph

ogly

cera

te k

inas

e23

5.6

5050

7.6

5.06

2fe

r1_s

caff_

344_

GE

NE

_9co

nser

ved

hypo

thet

ical

(onl

y fe

r1)

529.

415

98.

91.

562.

962

fer1

_sca

ff_35

_GE

NE

_40

H(+

)-tra

nspo

rting

ATP

ase

876.

30

02.

60.

862

fer1

_sca

ff_35

_GE

NE

_9D

NA

pol

ymer

ase

895.

70

01.

90.

63

2fe

r1_s

caff_

431_

GE

NE

_3tra

nspo

sase

35

8.8

113

199.

59.

52

fer1

_sca

ff_45

0_G

EN

E_4

SW

F/S

NF

fam

ily h

elic

ase

115

5.9

016

81.

90.

632

2fe

r1_s

caff_

476_

GE

NE

_5ty

pe I

rest

rictio

n-m

odifi

catio

n en

zym

e, S

sub

unit

479.

443

415.

61.

862

fer1

_sca

ff_49

4_G

EN

E_7

glut

amyl

-tRN

A s

ynth

etas

e 41

614

014

04.

21.

42

fer1

_sca

ff_52

_GE

NE

_31

form

ate-

-tetra

hydr

ofol

ate

ligas

e57

6.9

00

20.

662

fer1

_sca

ff_52

_GE

NE

_33

ribon

ucle

otid

e re

duct

ase

898.

40

08.

11.

431.

41.

131.

132

2fe

r1_s

caff_

572_

GE

NE

_5co

nser

ved

hypo

thet

ical

356.

564

4.4

1.46

2.93

2fe

r1_s

caff_

58_G

EN

E_3

3ca

rbon

mon

oxid

e de

hydr

ogen

ase

beta

sub

unit

715.

30

03.

41.

132

fer1

_sca

ff_59

0_G

EN

E_3

H+

ATP

ase

subu

nit C

416

9191

7.4

2.46

2fe

r1_s

caff_

63_G

EN

E_1

3ch

aper

one

prot

ein

Dna

K69

5.6

00

5.5

1.83

22

fer1

_sca

ff_63

_GE

NE

_2tra

nspo

sase

40

9.8

117

798.

62.

862

fer1

_sca

ff_64

6_G

EN

E_2

type

I re

stric

tion

enzy

me

114

5.9

111

111

1.7

0.56

2fe

r1_s

caff_

65_G

EN

E_1

7se

rine/

thre

onin

e pr

otei

n ki

nase

309.

477

7716

.95.

632

fer1

_sca

ff_74

_GE

NE

_18

repl

icat

ion

fact

or A

, sin

gle-

stra

nded

DN

A b

indi

ng p

rote

in18

4.9

3434

17.7

5.9

2fe

r1_s

caff_

78_G

EN

E_1

3am

ino

acid

per

mea

se66

9.1

00

1.5

0.5

2fe

r1_s

caff_

78_G

EN

E_8

cons

erve

d hy

poth

etic

al46

914

37.

82.

62

2fe

r1_s

caff_

84_G

EN

E_7

chro

mos

ome

parti

tion

prot

ein

smc

132

5.5

00

2.3

0.76

2fe

r1_s

caff_

857_

GE

NE

_2A

BC

tran

spor

ter,

ATP

-bin

ding

pro

tein

214.

774

7413

.84.

62

fer1

_sca

ff_87

2_G

EN

E_4

ATP

-dep

ende

nt p

rote

ase

La51

5.7

00

3.1

3.1

2fe

r1_s

caff_

873_

GE

NE

_1m

agne

sium

che

lata

se s

ubun

it, C

obN

575

00

2.6

1.73

2fe

r1_s

caff_

100_

GE

NE

_11

cons

erve

d hy

poth

etic

al20

614

6.7

4.46

2fe

r1_s

caff_

119_

GE

NE

_3ph

osph

orib

osyl

form

ylgl

ycin

amid

ine

synt

hase

835.

40

04.

71.

172

fer1

_sca

ff_13

6_G

EN

E_5

sulfi

de d

ehyd

roge

nase

(fla

vocy

toch

rom

e C

)42

5.3

116

116

3.2

1.06

2fe

r1_s

caff_

34_G

EN

E_4

48-

oxog

uani

ne D

NA

gly

cosy

lase

259.

547

4312

.93.

222

fer1

_sca

ff_36

1_G

EN

E_7

trans

posa

se

458.

887

877.

62.

532

fer1

_sca

ff_43

1_G

EN

E_7

carb

on m

onox

ide

dehy

drog

enas

e be

ta s

ubun

it71

50

03.

40.

852

fer1

_sca

ff_49

_GE

NE

_31

DN

A p

olym

eras

e II

larg

e su

buni

t12

25.

30

01.

90.

472

fer1

_sca

ff_54

7_G

EN

E_2

sing

le-s

trand

ed-D

NA

-spe

cific

exo

nucl

ease

Rec

J49

514

714

76.

11.

522

fer1

_sca

ff_58

_GE

NE

_11

pyrid

oxin

e bi

osyn

thes

is p

rote

in36

5.7

137

137

5.5

3.66

2fe

r1_s

caff_

646_

GE

NE

_3co

nser

ved

hypo

thet

ical

(onl

y fe

r1) (

329-

2, 6

46-3

)16

1057

82

2fe

r1_s

caff_

721_

GE

NE

_5fo

rmat

e de

hydr

ogen

ase

alph

a ch

ain

626.

10

02

0.5

2fe

r1_s

caff_

74_G

EN

E_1

0co

nser

ved

hypo

thet

ical

264.

662

4.9

1.22

Tota

l = 7

2 (7

4 - 2

dup

licat

es)

2fe

r2_s

caff_

1_G

EN

E_1

6D

NA

pol

ymer

ase,

larg

e ch

ain

895.

60

04.

71.

962

fer2

_sca

ff_1_

GE

NE

_48

DN

A p

olym

eras

e IV

297.

767

676.

52.

162

fer2

_sca

ff_1_

GE

NE

_50

cons

erve

d hy

poth

etic

al (o

nly

fer1

)14

9.6

277.

44.

932

fer2

_sca

ff_1_

GE

NE

_57

cons

erve

d hy

poth

etic

al (s

imila

r to

rest

rictio

n en

donu

clea

se)

549.

957

82.

10.

72

fer2

_sca

ff_1_

GE

NE

_62

med

ium

-cha

in-fa

tty-a

cid-

-CoA

liga

se

595.

50

04.

41.

462

fer2

_sca

ff_1_

GE

NE

_64

acyl

-CoA

deh

ydro

gena

se40

512

112

16.

72.

232

fer2

_sca

ff_10

3_G

EN

E_1

1fo

rmyl

tetra

hydr

ofol

ate

synt

heta

se (1

03-1

1, 5

56-1

)58

6.4

00

6.1

2.03

2fe

r2_s

caff_

104_

GE

NE

_23

sign

al re

cogn

ition

par

ticle

pro

tein

246.

944

446.

92.

32

fer2

_sca

ff_10

7_G

EN

E_1

7tra

nspo

sase

(38-

50, 1

0-63

, 107

-17)

315.

432

107.

92.

632

fer2

_sca

ff_11

_GE

NE

_10

2-ph

osph

ogly

cera

te k

inas

e23

5.7

8049

7.6

5.06

2fe

r2_s

caff_

11_G

EN

E_1

3A

AA

fam

ily A

TPas

e/ce

ll di

visi

on c

ontro

l pro

tein

cdc

48 (3

4-37

, 182

5.3

00

8.7

1.5

2.56

2fe

r2_s

caff_

11_G

EN

E_1

5eu

kary

otic

pep

tide

chai

n re

leas

e fa

ctor

sub

unit

147

5.4

00

1.7

0.56

2fe

r2_s

caff_

11_G

EN

E_2

0N

-ace

tylg

luco

sam

ine

kina

se35

5.9

8080

10.8

3.6

2fe

r2_s

caff_

118_

GE

NE

_14

(sim

ilar t

o 14

8-6)

ther

mos

ome,

alp

ha c

hain

/arc

haea

l cha

pero

n58

5.4

00

8.1

2.7

2fe

r2_s

caff_

118_

GE

NE

_19

cons

erve

d hy

poth

etic

al (

40-1

, 118

-19)

269.

216

9.3

3.1

2fe

r2_s

caff_

12_G

EN

E_1

0ar

giny

l-tR

NA

syn

thet

ase

635.

516

616

64.

12.

732

fer2

_sca

ff_12

_GE

NE

_51

gluc

oam

ylas

e (9

86-1

, 12-

51)

696.

10

03.

81.

262

fer2

_sca

ff_12

_GE

NE

_56

suga

r AB

C tr

ansp

orte

r 1, A

TP b

indi

ng p

rote

in (9

49-2

, 12-

56)

385.

812

412

49.

53.

165.

32

fer2

_sca

ff_12

_GE

NE

_63-

phos

phos

hiki

mat

e 1-

carb

oxyv

inyl

trans

fera

se47

6.7

9898

4.5

1.5

2fe

r2_s

caff_

15_G

EN

E_4

1D

NA

-dire

cted

RN

A p

olym

eras

e su

buni

t A' (

15-4

1, 6

5-12

)10

06

00

3.5

0.33

1.5

2fe

r2_s

caff_

152_

GE

NE

_11

suga

r kin

ase

(rib

okin

ase

fam

ily) (

50-1

4, 1

52-1

1)33

576

769.

83.

262

fer2

_sca

ff_15

2_G

EN

E_8

enol

ase

(50-

11, 1

52-8

)44

5.3

157

157

9.5

1.66

2.23

2.23

2fe

r2_s

caff_

17_G

EN

E_2

3co

nser

ved

hypo

thet

ical

156.

824

14.5

4.83

2fe

r2_s

caff_

17_G

EN

E_5

4fo

rmat

e de

hydr

ogen

ase

chai

n A

110

60

04

2.66

1.33

2fe

r2_s

caff_

17_G

EN

E_6

6(s

imila

r to

36-5

2) D

NA

topo

isom

eras

e I

789

00

3.4

1.13

2fe

r2_s

caff_

171_

GE

NE

_8Fe

-S o

xido

redu

ctas

e63

6.4

00

6.3

6.3

22

fer2

_sca

ff_19

_GE

NE

_16

DN

A g

yras

e su

buni

t A (1

sim

ilar t

o 49

4-1)

896.

50

02.

90.

961.

262

fer2

_sca

ff_19

_GE

NE

_25

uniq

ue h

ypot

hetic

al (n

ot in

fer1

)10

5.4

82.

662

fer2

_sca

ff_19

_GE

NE

_57

cons

erve

d hy

poth

etic

al (6

94-5

, 19-

57)

859.

513

2.6

0.86

2fe

r2_s

caff_

216_

GE

NE

_7N

AD

H o

xido

redu

ctas

e (2

16-7

, 962

-3)

626.

60

08.

92.

962

fer2

_sca

ff_22

7_G

EN

E_1

1co

nser

ved

hypo

thet

ical

159.

120

227.

332

fer2

_sca

ff_24

_GE

NE

_11

(863

-3, 2

4-11

) mol

ybdo

pter

in b

iosy

nthe

sis

Moe

B p

rote

in

295.

964

6414

.84.

932

fer2

_sca

ff_24

_GE

NE

_27

DN

A p

olym

eras

e el

onga

tion

subu

nit

749.

212

912

93

12

fer2

_sca

ff_24

_GE

NE

_28

cell

divi

sion

con

trol p

rote

in 6

/AA

A A

TPas

e (v

. sim

ilar t

o 40

7-7)

405.

479

796.

42.

132

fer2

_sca

ff_24

7_G

EN

E_4

NA

D-d

epen

dent

ald

ehyd

e de

hydr

ogen

ase

545.

415

815

84

1.33

2fe

r2_s

caff_

247_

GE

NE

_9co

nser

ved

hypo

thet

ical

(516

-4, 2

47-9

, sim

ilar t

o 31

0-4)

(sim

ilar

469.

852

72.

50.

832

fer2

_sca

ff_29

_GE

NE

_26

ribos

omal

pro

tein

S15

1710

4343

165.

332

fer2

_sca

ff_31

_GE

NE

_14

thio

redo

xin

redu

ctas

e36

5.9

117

117

8.1

2.7

22

fer2

_sca

ff_31

_GE

NE

_15

diph

tham

ide

synt

hase

sub

unit

DP

H2

385.

811

511

58.

72.

92

fer2

_sca

ff_31

_GE

NE

_43

FixC

, ele

ctro

n tra

nsfe

r fla

vopr

otei

n 47

5.2

010

76.

22.

062

fer2

_sca

ff_31

0_G

EN

E_4

cons

erve

d hy

poth

etic

al (s

imila

r to

rest

rictio

n en

donu

clea

ses)

549.

856

2.1

0.7

2fe

r2_s

caff_

36_G

EN

E_1

8co

nser

ved

hypo

thet

ical

508.

775

4.3

1.43

2fe

r2_s

caff_

36_G

EN

E_2

2m

RN

A 3

'-end

pro

cess

ing

fact

or46

5.6

00

7.6

2.53

2fe

r2_s

caff_

36_G

EN

E_2

3co

nser

ved

hypo

thet

ical

(onl

y fe

r1)

288.

631

20.3

9.33

2fe

r2_s

caff_

36_G

EN

E_4

6S

-ade

nosy

lmet

hion

ine

synt

heta

se (s

imila

r to

203-

7)45

5.7

00

2.2

0.73

2fe

r2_s

caff_

36_G

EN

E_5

0ph

osph

orib

osyl

amin

oim

idaz

olec

arbo

xam

ide

form

yltra

nsfe

rase

566.

716

216

24.

21.

42

fer2

_sca

ff_36

6_G

EN

E_4

long

-cha

in fa

tty-a

cid-

CoA

liga

se58

6.1

010

63.

71.

22

fer2

_sca

ff_37

_GE

NE

_33

cons

erve

d hy

poth

etic

al23

4.7

107

31.6

16.3

2fe

r2_s

caff_

37_G

EN

E_3

7co

nser

ved

hypo

thet

ical

334.

816

014

4.66

2fe

r2_s

caff_

37_G

EN

E_6

cons

erve

d hy

poth

etic

al39

6.3

144

6.1

2.03

2fe

r2_s

caff_

38_G

EN

E_2

co

nser

ved

hypo

thet

ical

(sim

ilar t

o 90

5-3,

945

-3)

679.

128

5.4

1.8

2fe

r2_s

caff_

38_G

EN

E_2

9ac

etyl

-CoA

ace

tyltr

ansf

eras

e42

5.8

165

165

5.6

1.86

2fe

r2_s

caff_

38_G

EN

E_3

8ph

osph

oeno

lpyr

uvat

e sy

ntha

se89

5.2

00

7.8

0.66

0.5

4.2

2fe

r2_s

caff_

385_

GE

NE

_2un

ique

hyp

othe

tical

(not

in fe

r1)

1910

821

.27.

062

fer2

_sca

ff_38

5_G

EN

E_4

cons

erve

d hy

poth

etic

al64

5.9

107.

32.

234.

13.

72

fer2

_sca

ff_39

_GE

NE

_24

glyc

erol

-3-p

hosp

hate

deh

ydro

gena

se51

9.2

4545

32

2fe

r2_s

caff_

39_G

EN

E_3

2ac

etyl

trans

fera

se

266.

319

1910

3.33

2fe

r2_s

caff_

39_G

EN

E_4

3(s

imila

r to

946-

5) c

itrat

e sy

ntha

se42

5.9

121

121

5.4

1.8

2fe

r2_s

caff_

40_G

EN

E_1

cons

erve

d hy

poth

etic

al (1

18-1

9, 4

0-1)

229

1310

.53.

52

fer2

_sca

ff_46

4_G

EN

E_1

succ

inat

e se

mia

ldeh

yde

dehy

drog

enas

e (4

64-1

, 18-

12, 1

8-13

)34

5.4

154

738

2.7

2fe

r2_s

caff_

47_G

EN

E_1

5co

nser

ved

hypo

thet

ical

355.

656

4.4

1.46

2fe

r2_s

caff_

5_G

EN

E_1

8th

iosu

lfate

sul

furtr

ansf

eras

e19

9.3

3232

14.5

4.83

2fe

r2_s

caff_

5_G

EN

E_3

0co

nser

ved

hypo

thet

ical

234.

957

14.9

4.96

2fe

r2_s

caff_

5_G

EN

E_3

2ss

DN

A-b

indi

ng p

rote

in39

5.8

101

101

165.

332

fer2

_sca

ff_5_

GE

NE

_84

euka

ryot

ic-ty

pe D

NA

prim

ase

398.

766

667.

72.

562

2fe

r2_s

caff_

5_G

EN

E_8

5X

aa-P

ro d

ipep

tidas

e40

5.5

133

133

74.

662.

332

fer2

_sca

ff_50

_GE

NE

_11

enol

ase

(50-

11, 1

52-8

)44

5.2

158

158

9.5

1.66

2.23

2.23

2fe

r2_s

caff_

50_G

EN

E_1

9co

nser

ved

hypo

thet

ical

509.

161

6.5

2.16

2fe

r2_s

caff_

50_G

EN

E_2

4gl

ucoa

myl

ase

735.

40

04.

44.

41.

462

fer2

_sca

ff_52

2_G

EN

E_1

gluc

oam

ylas

e (5

22-1

, 986

-1)

527.

115

615

65.

11.

72

fer2

_sca

ff_55

_GE

NE

_13

trans

crip

tiona

l reg

ulat

or25

5.8

5039

7.3

7.3

2fe

r2_s

caff_

55_G

EN

E_1

5A

BC

tran

spor

ter A

TP-b

indi

ng p

rote

in95

6.1

011

84.

20.

631

2fe

r2_s

caff_

55_G

EN

E_2

7se

rine

prot

ease

(sim

ilar t

o 49

5-4)

345.

855

528.

42.

82.

062

fer2

_sca

ff_55

6_G

EN

E_1

form

ylte

trahy

drof

olat

e sy

nthe

tase

(3%

div

erge

nt fr

om 1

03-1

1)

425.

613

012

78.

42.

82

fer2

_sca

ff_56

_GE

NE

_25

uniq

ue h

ypot

hetic

al (n

ot in

fer1

)12

119.

33.

12

fer2

_sca

ff_64

_GE

NE

_6co

nser

ved

hypo

thet

ical

(onl

y in

fer1

)11

6.5

3126

.58.

832

fer2

_sca

ff_70

_GE

NE

_3un

ique

hyp

othe

tical

(not

in fe

r1)

259.

411

.23.

732

fer2

_sca

ff_71

1_G

EN

E_2

orni

thin

e cy

clod

eam

inas

e (3

7-24

, 37-

25, 7

11-2

)33

5.8

138

899.

53.

22

fer2

_sca

ff_74

4_G

EN

E_1

ATP

ase

(91-

9, 7

44-1

)49

8.9

6332

51.

72

fer2

_sca

ff_86

3_G

EN

E_3

mol

ybdo

pter

in b

iosy

nthe

sis

Moe

B p

rote

in (8

63-3

, 24-

11)

296.

262

6214

.84.

932

fer2

_sca

ff_9_

GE

NE

_18

ther

mos

ome

subu

nit/c

hape

roni

n50

5.1

179

179

3.3

1.1

2fe

r2_s

caff_

9_G

EN

E_2

9(9

67-1

, 9-2

9) A

BC

tran

spor

ter,

ATP

-bin

ding

pro

tein

295.

113

410

79.

93.

32

fer2

_sca

ff_9_

GE

NE

_36

ATP

pho

spho

ribos

yltra

nsfe

rase

238.

454

5411

.911

.92

fer2

_sca

ff_9_

GE

NE

_37

hist

idin

ol d

ehyd

roge

nase

426.

611

911

96.

72.

232

2fe

r2_s

caff_

9_G

EN

E_6

3N

2,N

2-di

met

hylg

uano

sine

tRN

A m

ethy

ltran

sfer

ase

406.

593

939.

12.

25.

232.

22

fer2

_sca

ff_9_

GE

NE

_7tra

nspo

sase

43

9.3

3333

7.3

2.43

2fe

r2_s

caff_

93_G

EN

E_1

3A

TP-d

epen

dent

pro

teas

e Lo

n56

6.1

057

12.6

3.26

3.8

6.7

2fe

r2_s

caff_

97_G

EN

E_5

A1A

O H

+ A

TPas

e su

buni

t A12

75.

60

02.

20.

732

fer2

_sca

ff_97

_GE

NE

_7A

1AO

H+

ATP

ase

subu

nit C

416.

287

873.

72.

462

2fe

r2_s

caff_

1_G

EN

E_1

07D

NA

prim

ase

smal

l sub

unit

(899

-4, 1

-107

)44

6.1

9191

5.3

1.32

2fe

r2_s

caff_

1001

_GE

NE

_2N

AD

-dep

ende

nt a

ldeh

yde

dehy

drog

enas

e54

5.8

016

19.

91.

32.

92

fer2

_sca

ff_11

_GE

NE

_34

cons

erve

d hy

poth

etic

al (1

1-34

, 621

-4)

488.

299

2.7

0.9

2fe

r2_s

caff_

11_G

EN

E_3

8gl

ycer

ol-3

-pho

spha

te c

ytid

ylyl

trans

fera

se37

9.1

9191

17.6

5.86

2fe

r2_s

caff_

118_

GE

NE

_18

cons

erve

d hy

poth

etic

al21

9.1

839

2.25

2fe

r2_s

caff_

15_G

EN

E_4

2D

NA

-dire

cted

RN

A p

olym

eras

e su

buni

t b13

56

00

3.2

0.8

2fe

r2_s

caff_

166_

GE

NE

_5co

nser

ved

hypo

thet

ical

(sim

ilar t

o O

-link

ed G

lcN

Ac

trans

fera

se58

5.1

329

2.7

0.67

2fe

r2_s

caff_

205_

GE

NE

_63-

isop

ropy

lmal

ate

dehy

drog

enas

e40

5.1

9898

5.1

1.7

2fe

r2_s

caff_

24_G

EN

E_5

4tR

NA

nuc

leot

idyl

trans

fera

se (2

4-54

, 368

-7)

498.

112

012

05.

41.

352

fer2

_sca

ff_27

6_G

EN

E_8

trans

posa

se (5

-95,

276

-8)

458.

887

877.

62.

532

fer2

_sca

ff_36

_GE

NE

_28

phos

phog

lyce

rate

mut

ase

225.

757

4316

.94.

222

fer2

_sca

ff_36

8_G

EN

E_7

tRN

A n

ucle

otid

yltra

nsfe

rase

498.

112

012

05.

41.

352

fer2

_sca

ff_47

_GE

NE

_34

trypt

opha

n sy

ntha

se b

eta

chai

n45

6.7

00

6.8

1.7

2fe

r2_s

caff_

5_G

EN

E_9

5tra

nspo

sase

(5-9

5, 2

76-8

)45

8.8

100

877.

62.

532

fer2

_sca

ff_64

_GE

NE

_1tra

nspo

sase

61

9.4

3634

4.8

1.2

2fe

r2_s

caff_

89_G

EN

E_2

fucu

lose

-1-p

hosp

hate

ald

olas

e (8

9-2

are

a 89

-4 s

plit

gene

)24

6.2

7272

12.4

3.1

2fe

r2_s

caff_

89_G

EN

E_4

fucu

lose

-1-p

hosp

hate

ald

olas

e (8

9-2

are

a 89

-4 s

plit

gene

)18

770

5216

.64.

152

fer2

_sca

ff_90

_GE

NE

_8co

nser

ved

hypo

thet

ical

255.

626

9.7

2.42

3.23

2fe

r2_s

caff_

962_

GE

NE

_3N

AD

H o

xido

redu

ctas

e (2

16-7

, 962

-3)

86.

611

1139

.19.

77To

tal =

99

(108

- 9

dupl

icat

es)

2gp

l_sc

aff_

105_

GE

NE

_15

flavo

prot

ein

invo

lved

in p

anto

then

ate

met

abol

ism

446.

171

714.

91.

632

2gp

l_sc

aff_

105_

GE

NE

_17

triac

ylgl

ycer

ol li

pase

/est

eras

e26

5.4

4340

7.2

7.2

7.2

7.2

7.2

2gp

l_sc

aff_

105_

GE

NE

_19

phos

phoe

nolp

yruv

ate

synt

hase

655.

90

05.

71.

92

gpl_

scaf

f_10

8_G

EN

E_2

1di

hydr

olip

oam

ide

acet

yltra

nsfe

rase

207.

846

4618

.76.

232

gpl_

scaf

f_10

9_G

EN

E_2

2py

ruva

te fe

rred

oxin

oxi

dore

duct

ase

(281

-1, 1

09-2

2)26

5.2

7676

7.8

2.6

2gp

l_sc

aff_

1096

_GE

NE

_2ni

cotin

ate-

nucl

eotid

e--d

imet

hylb

enzi

mid

azol

e ph

osph

orib

osyl

tr35

5.4

5857

8.3

2.76

2gp

l_sc

aff_

112_

GE

NE

_12

uniq

ue h

ypot

hetic

al (w

eak

sim

ilar t

o fe

r1)

95.

18

36.4

12.1

2gp

l_sc

aff_

112_

GE

NE

_6co

nser

ved

hypo

thet

ical

708.

30

3.6

1.2

2gp

l_sc

aff_

114_

GE

NE

_11

acet

ylgl

utam

ate

kina

se (a

rgB

)28

9.5

4747

5.1

1.7

22

gpl_

scaf

f_11

4_G

EN

E_2

cons

erve

d hy

poth

etic

al36

6.2

695.

52.

81.

831.

832

gpl_

scaf

f_11

4_G

EN

E_6

Asp

arto

kina

se b

eta

(reg

ulat

ory)

sub

unit

229.

434

348.

62.

862

gpl_

scaf

f_11

57_G

EN

E_2

trans

posa

se (1

157-

2, 2

48-2

)44

9.1

9144

4.8

1.6

22

gpl_

scaf

f_12

1_G

EN

E_1

150

S ri

boso

mal

pro

tein

L7A

147.

734

3463

.154

.63

2gp

l_sc

aff_

121_

GE

NE

_12

ribos

omal

pro

tein

S28

710

2020

34.8

11.6

22

gpl_

scaf

f_12

1_G

EN

E_5

cons

erve

d hy

poth

etic

al12

1024

217

2gp

l_sc

aff_

124_

GE

NE

_11

aldo

/ket

o re

duct

ase

356.

468

536.

12.

032.

032

gpl_

scaf

f_12

4_G

EN

E_1

7m

ethi

onin

e sy

ntha

se II

(cob

alam

in-in

depe

nden

t)41

611

711

76.

72.

232

gpl_

scaf

f_12

6_G

EN

E_1

chro

mos

ome

parti

tion

prot

ein

smc

525.

135

355

1.66

2gp

l_sc

aff_

129_

GE

NE

_92-

met

hylth

ioad

enin

e sy

nthe

tase

325.

491

9113

.84.

62

gpl_

scaf

f_13

3_G

EN

E_1

34-

amin

obut

yrat

e am

inot

rans

fera

se50

6.6

177

175

7.7

2.56

22

gpl_

scaf

f_15

5_G

EN

E_1

2co

nser

ved

hypo

thet

ical

358.

844

17.6

7.43

22

gpl_

scaf

f_15

5_G

EN

E_4

smal

l sub

unit

ribos

omal

pro

tein

S19

E17

9.4

4036

51.3

419

.33

2gp

l_sc

aff_

156_

GE

NE

_7m

olyb

denu

m c

ofac

tor b

iosy

nthe

sis

prot

ein

696.

30

04

1.33

2gp

l_sc

aff_

156_

GE

NE

_8co

nser

ved

hypo

thet

ical

135

1024

.18.

032

gpl_

scaf

f_16

_GE

NE

_15

50S

ribo

som

al p

rote

in L

12E

114.

916

1617

.85.

932

gpl_

scaf

f_16

_GE

NE

_16

50S

ribo

som

al p

rote

in L

1034

5.7

7575

8.1

8.1

2gp

l_sc

aff_

16_G

EN

E_1

8rib

osom

al p

rote

in L

116

9.2

4528

9.13

9.33

2gp

l_sc

aff_

16_G

EN

E_1

9co

nser

ved

hypo

thet

ical

218.

727

17.2

5.73

2gp

l_sc

aff_

16_G

EN

E_2

33-

hydr

oxy-

3-m

ethy

lglu

tary

l-CoA

-syn

thas

e/3-

oxoa

cyl-[

acyl

-car

ri38

5.4

151

145

12.5

4.16

2gp

l_sc

aff_

16_G

EN

E_4

3un

ique

hyp

othe

tical

(sim

ilar t

o st

erol

car

rier p

rote

in 2

/3-o

xoac

y12

6.3

54

70.3

18.9

329

.73

2gp

l_sc

aff_

16_G

EN

E_4

53-

hydr

oxya

cyl-C

oA d

ehyd

roge

nase

318.

780

809.

43.

132

gpl_

scaf

f_16

_GE

NE

_6is

ocitr

ate

dehy

drog

enas

e45

5.6

00

9.9

5.03

2gp

l_sc

aff_

16_G

EN

E_6

0ac

etyl

tran

sfer

ase

216.

629

2812

.84.

262

gpl_

scaf

f_16

_GE

NE

_9G

TP-b

indi

ng p

rote

in

409.

111

711

78

2.66

2gp

l_sc

aff_

165_

GE

NE

_13

mul

tidru

g ef

flux

perm

ease

4410

6312

113.

662

gpl_

scaf

f_16

5_G

EN

E_8

uniq

ue h

ypot

hetic

al36

6.4

5.5

1.83

2gp

l_sc

aff_

169_

GE

NE

_4tra

nsla

tion

elon

gatio

n fa

ctor

EF-

147

8.5

00

34.4

5.5

14.9

32

gpl_

scaf

f_16

9_G

EN

E_5

30S

ribo

som

al p

rote

in S

1012

9.3

3939

14.4

14.4

22

gpl_

scaf

f_16

9_G

EN

E_6

trans

latio

n el

onga

tion

fact

or E

F-2

816.

20

012

.34.

662

gpl_

scaf

f_16

9_G

EN

E_9

cons

erve

d hy

poth

etic

al17

4.7

1514

9.33

2gp

l_sc

aff_

193_

GE

NE

_3gl

ycos

yltra

nsfe

rase

45

9.6

6060

3.5

1.16

2gp

l_sc

aff_

196_

GE

NE

_11

cons

erve

d hy

poth

etic

al13

833

33.1

827

.03

2gp

l_sc

aff_

196_

GE

NE

_3nu

cleo

id D

NA

-bin

ding

pro

tein

1010

2020

23.3

8.13

15.5

323

.32

gpl_

scaf

f_19

6_G

EN

E_4

cons

erve

d hy

poth

etic

al11

9.4

1030

.230

.22

gpl_

scaf

f_20

0_G

EN

E_1

cons

erve

d hy

poth

etic

al (1

096-

2, 2

00-1

)30

5.5

4110

3.33

2gp

l_sc

aff_

200_

GE

NE

_10

pref

oldi

n su

buni

t bet

a14

5.7

1919

20.2

6.73

2gp

l_sc

aff_

200_

GE

NE

_86,

7-di

met

hyl-8

-rib

ityllu

maz

ine

synt

hase

15

5.4

3828

.49.

462

gpl_

scaf

f_20

8_G

EN

E_1

DN

A g

yras

e (to

pois

omer

ase

II)66

5.7

00

5.1

1.7

2gp

l_sc

aff_

238_

GE

NE

_4H

+ A

TPas

e, s

ubun

it I

728.

414

114

19

1.76

5.56

32

gpl_

scaf

f_24

0_G

EN

E_4

cons

erve

d hy

poth

etic

al10

4.9

2224

.78.

232

gpl_

scaf

f_24

4_G

EN

E_7

chap

eron

e pr

otei

n D

naK

675

00

17.5

1.36

5.2

1.1

2gp

l_sc

aff_

248_

GE

NE

_2tra

nspo

sase

(115

7-2,

248

-2)

209.

734

1110

.63.

532

gpl_

scaf

f_24

8_G

EN

E_6

uniq

ue h

ypot

hetic

al49

9.3

4.7

1.56

2gp

l_sc

aff_

252_

GE

NE

_11

uniq

ue h

ypot

hetic

al (n

o fe

r1!)

215.

110

.13.

362

gpl_

scaf

f_25

2_G

EN

E_5

DN

A p

olym

eras

e II

smal

l sub

unit

228.

834

16.9

8.2

2gp

l_sc

aff_

254_

GE

NE

_1rib

osom

al p

rote

in L

428

1072

14.7

4.9

2gp

l_sc

aff_

254_

GE

NE

_7Fe

-S o

xido

redu

ctas

e49

6.1

104

102

4.9

1.63

1.1

2gp

l_sc

aff_

255_

GE

NE

_3rib

osom

al p

rote

in L

1523

1169

699.

13.

032

gpl_

scaf

f_25

5_G

EN

E_8

ther

mos

ome

beta

cha

in/c

hape

roni

n58

5.2

00

30.4

6.63

7.63

6.26

2gp

l_sc

aff_

256_

GE

NE

_1m

alat

e de

hydr

ogen

ase

357.

713

313

326

.18.

13.

32

gpl_

scaf

f_25

6_G

EN

E_1

1ss

DN

A-b

indi

ng p

rote

in39

6.4

5849

10.7

3.56

2gp

l_sc

aff_

257_

GE

NE

_3V

-type

ATP

syn

thas

e al

pha

chai

n63

5.5

00

7.8

1.66

1.66

2gp

l_sc

aff_

267_

GE

NE

_1co

nser

ved

hypo

thet

ical

735.

215

4.6

1.53

2gp

l_sc

aff_

279_

GE

NE

_3tre

halo

se s

ynth

ase

295.

123

202.

81.

862

gpl_

scaf

f_27

9_G

EN

E_8

acet

yl-C

oA a

cety

ltran

sfer

ase

445.

916

016

010

.23.

42

gpl_

scaf

f_28

_GE

NE

_34

DN

A-d

irect

ed R

NA

pol

ymer

ase

596

139

139

3.8

1.26

2gp

l_sc

aff_

281_

GE

NE

_1py

ruva

te fe

rred

oxin

oxi

dore

duct

ase

(109

-22,

281

-1)

425.

214

014

04.

81.

62

gpl_

scaf

f_28

1_G

EN

E_6

prot

easo

me

alph

a su

buni

t26

5.3

9292

36.3

8.53

9.26

8.4

2gp

l_sc

aff_

285_

GE

NE

_5si

te-s

peci

fic re

com

bina

se23

9.9

8585

7.8

2.6

2gp

l_sc

aff_

286_

GE

NE

_2gl

ycer

ol-3

-pho

spha

te c

ytid

ylyl

trans

fera

se36

9.7

3523

7.9

2.63

2gp

l_sc

aff_

286_

GE

NE

_6co

nser

ved

hypo

thet

ical

275

4212

.34.

12

gpl_

scaf

f_30

4_G

EN

E_8

ATP

-dep

ende

nt h

elic

ase

387.

214

113

72

0.66

2gp

l_sc

aff_

328_

GE

NE

_6pe

ptid

yl-p

roly

l cis

-tran

s is

omer

ase

295

5555

5.1

1.7

2gp

l_sc

aff_

338_

GE

NE

_3as

para

giny

l-tR

NA

syn

thet

ase

395.

496

9624

.89.

665.

232

gpl_

scaf

f_34

6_G

EN

E_2

nucl

eola

r pro

tein

Nop

56 (1

000-

1, 3

46-2

)35

8.7

3514

16.8

5.6

22

gpl_

scaf

f_36

7_G

EN

E_5

DN

A g

lyco

syla

se

269.

251

459.

43.

132

gpl_

scaf

f_37

3_G

EN

E_1

uniq

ue h

ypot

hetic

al (n

ot in

fer1

!)43

9.6

4.6

1.53

2gp

l_sc

aff_

373_

GE

NE

_2co

nser

ved

hypo

thet

ical

(763

-2, 3

73-2

)24

8.6

2810

.97.

262

gpl_

scaf

f_37

3_G

EN

E_3

(763

-1, 3

73-3

) ATP

-dep

ende

nt p

rote

ase

La30

5.4

108

108

103.

335.

62

2gp

l_sc

aff_

379_

GE

NE

_2A

BC

tran

spor

ter,

ATP

bin

ding

pro

tein

295.

180

802.

70.

92

2gp

l_sc

aff_

384_

GE

NE

_1ol

igop

eptid

e A

BC

tran

spor

ter

374.

963

6317

.412

.66

10.7

4.9

14.7

2gp

l_sc

aff_

393_

GE

NE

_2N

-eth

ylam

mel

ine

chlo

rohy

drol

ase

385.

863

633.

61.

22

gpl_

scaf

f_39

3_G

EN

E_6

cons

erve

d hy

poth

etic

al9

5.8

1418

.56.

162

gpl_

scaf

f_40

5_G

EN

E_6

8-am

ino-

7-ox

onon

anoa

te s

ynth

etas

e 43

6.2

157

157

8.4

2.8

2gp

l_sc

aff_

411_

GE

NE

_5un

ique

hyp

othe

tical

(sim

ilar t

o O

-link

ed G

lnN

Ac

trans

fera

se)

575.

48

84.

31.

432

gpl_

scaf

f_41

4_G

EN

E_3

cons

erve

d hy

poth

etic

al51

5.7

583

12

gpl_

scaf

f_45

6_G

EN

E_3

nucl

eotid

e-bi

ndin

g pr

otei

n (U

spA

-rel

ated

)30

9.7

4744

4.1

1.36

2gp

l_sc

aff_

466_

GE

NE

_1S

AM

-dep

ende

nt m

ethy

ltran

sfer

ase

(481

-2, 4

66-1

)22

6.2

2323

37.2

172

gpl_

scaf

f_47

9_G

EN

E_4

isol

eucy

l-tR

NA

syn

thet

ase

915.

70

02.

10.

72

gpl_

scaf

f_48

1_G

EN

E_2

SA

M-d

epen

dent

met

hyltr

ansf

eras

e (4

81-2

, 466

-1)

226.

223

2337

.217

2gp

l_sc

aff_

481_

GE

NE

_4su

ccin

ate

dehy

drog

enas

e, fl

avop

rote

in s

ubun

it64

5.8

150

132

11.5

4.73

2.1

2gp

l_sc

aff_

493_

GE

NE

_5co

nser

ved

hypo

thet

ical

225.

118

13.3

4.43

2gp

l_sc

aff_

498_

GE

NE

_4ca

tala

se/p

erox

idas

e81

5.4

00

1.8

0.6

22

gpl_

scaf

f_52

0_G

EN

E_2

ther

mos

ome,

alp

ha c

hain

/cha

pero

nin

586.

30

038

.611

.63

11.9

610

.33

2gp

l_sc

aff_

520_

GE

NE

_3su

ccin

yl-C

oA s

ynth

etas

e be

ta s

ubun

it41

5.5

143

143

13.9

3.16

3.53

2gp

l_sc

aff_

520_

GE

NE

_4su

ccin

yl-C

oA s

ynth

etas

e al

pha

chai

n (1

21-1

, 520

-4)

308.

410

810

88.

42.

8

2gp

l_sc

aff_

555_

GE

NE

_6co

nser

ved

hypo

thet

ical

187.

716

6.2

2.06

2.06

2gp

l_sc

aff_

596_

GE

NE

_2rib

osom

al p

rote

in S

1517

1043

4216

.65.

532

gpl_

scaf

f_60

1_G

EN

E_3

cons

erve

d hy

poth

etic

al20

8.8

5126

.78.

92

gpl_

scaf

f_62

0_G

EN

E_1

acyl

-CoA

deh

ydro

gena

se (6

20-1

, 180

-1)

625.

413

813

15.

51.

832

gpl_

scaf

f_65

2_G

EN

E_4

acon

itate

hyd

rata

se51

5.5

151

151

11.9

4.3

5.73

2gp

l_sc

aff_

658_

GE

NE

_1H

(+)-

trans

porti

ng A

TPas

e87

5.8

00

7.9

2.33

1.1

2gp

l_sc

aff_

688_

GE

NE

_4th

iore

doxi

n 15

6.4

2929

38.2

28.9

2gp

l_sc

aff_

79_G

EN

E_1

0D

NA

topo

isom

eras

e IA

909.

20

03.

11.

032

2gp

l_sc

aff_

79_G

EN

E_1

5S

-ade

nosy

lmet

hion

ine

synt

heta

se

445.

916

316

332

12.2

33.

2616

.16

10.2

2gp

l_sc

aff_

79_G

EN

E_7

serin

e hy

drox

ymet

hyltr

ansf

eras

e48

6.1

169

169

5.1

1.7

2gp

l_sc

aff_

803_

GE

NE

_2X

aa-P

ro d

ipep

tidas

e40

5.6

121

105

8.4

2.8

2gp

l_sc

aff_

887_

GE

NE

_3fla

vopr

otei

n (6

91-1

, 887

-3)

259.

278

768.

82.

932

2gp

l_sc

aff_

91_G

EN

E_1

0co

nser

ved

hypo

thet

ical

735.

291

12.6

1.86

3.6

4.7

2gp

l_sc

aff_

92_G

EN

E_1

32-

oxoa

cid-

-ferr

edox

in o

xido

redu

ctas

e, a

lpha

sub

unit

156.

140

3920

.86.

936.

932

gpl_

scaf

f_92

_GE

NE

_17

mem

bran

e m

etal

lopr

otea

se55

9.2

103

103

72.

332

gpl_

scaf

f_92

_GE

NE

_2un

ique

hyp

othe

tical

(992

-4, 9

2-2)

257.

67

10.5

3.5

2gp

l_sc

aff_

92_G

EN

E_2

1sm

all h

eat s

hock

pro

tein

(hsp

20)

215

4040

22.5

7.5

2gp

l_sc

aff_

95_G

EN

E_1

2ar

gini

ne d

eim

inas

e48

611

011

05.

71.

92

gpl_

scaf

f_95

_GE

NE

_14

cons

erve

d hy

poth

etic

al74

8.2

136

2.2

0.73

2gp

l_sc

aff_

95_G

EN

E_2

NA

D-d

epen

dent

ald

ehyd

e de

hydr

ogen

ase

568.

10

08.

41.

162.

22

gpl_

scaf

f_99

_GE

NE

_6co

nser

ved

hypo

thet

ical

129.

312

23.8

7.93

2gp

l_sc

aff_

99_G

EN

E_9

pero

xire

doxi

n 17

8.5

5454

45.2

11.4

622

.92

gpl_

scaf

f_10

9_G

EN

E_6

tRN

A n

ucle

otid

yltra

nsfe

rase

436.

677

776.

91.

722

gpl_

scaf

f_12

4_G

EN

E_1

cons

erve

d hy

poth

etic

al47

9.1

364.

71.

851.

82

gpl_

scaf

f_15

5_G

EN

E_1

0ce

ll di

visi

on p

rote

in [F

tsZ]

375

5757

11.8

2.95

2gp

l_sc

aff_

16_G

EN

E_1

0th

reon

ine

dehy

drat

ase

447.

612

011

99.

12.

272

gpl_

scaf

f_25

3_G

EN

E_5

trico

rn p

rote

ase

inte

ract

ing

fact

or F

2 (s

imila

r to

1047

-3)

915.

516

816

85

1.25

2gp

l_sc

aff_

91_G

EN

E_2

0co

nser

ved

hypo

thet

ical

(sim

ilar t

o A

TP-d

epen

dent

DN

A h

elic

a s47

6.3

384

5.6

1.4

2gp

l_sc

aff_

92_G

EN

E_1

5de

phos

pho-

CoA

kin

ase

226.

448

206.

51.

622

gpl_

scaf

f_92

_GE

NE

_16

phos

phor

ibos

ylfo

rmyl

glyc

inam

idin

e sy

ntha

se I

286

6161

7.2

1.8

Tota

l = 1

22 (1

26 -

4 du

plic

ates

)

22

Lept

oII_

scaf

f_11

08_G

EN

E_1

trans

crip

tion

elon

gatio

n fa

ctor

(110

8-1,

25-

60)

186

3636

81.2

46.2

324

.819

.16

56.0

349

.42

Lept

oII_

scaf

f_11

08_G

EN

E_3

uniq

ue h

ypot

hetic

al (s

imila

r to

trans

glyc

osyl

ases

)25

109

723

.419

.33

2Le

ptoI

I_sc

aff_

1147

_GE

NE

_3D

NA

topo

isom

eras

e74

9.5

143

143

5.4

1.8

2Le

ptoI

I_sc

aff_

115_

GE

NE

_5un

ique

hyp

othe

tical

199.

95.

33.

532

2Le

ptoI

I_sc

aff_

1153

_GE

NE

_2D

NA

or R

NA

hel

icas

e of

sup

erfa

mily

II (2

7-47

, 115

3-2)

346.

163

4941

.84.

5318

.13

2Le

ptoI

I_sc

aff_

120_

GE

NE

_10

suga

r fer

men

tatio

n st

imul

atio

n pr

otei

n17

5.7

2525

18.4

2.86

6.13

22

Lept

oII_

scaf

f_12

0_G

EN

E_1

1U

DP

-glu

cose

6-d

ehyd

roge

nase

48

613

813

844

.520

.33

28.9

12.2

62

2Le

ptoI

I_sc

aff_

120_

GE

NE

_12

glyc

ine

oxid

ase

(sar

cosi

ne o

xida

se)

417.

852

5224

.55.

8610

.66

8.63

8.8

22

Lept

oII_

scaf

f_12

0_G

EN

E_1

4m

embr

ane

efflu

x sy

stem

pro

tein

(25-

2, 1

20-1

4)20

913

1371

.659

.66

66.5

1865

.36

66.5

22

Lept

oII_

scaf

f_12

0_G

EN

E_3

heav

y m

etal

effl

ux p

ump,

Czc

A

113

100

014

.15.

939

1.86

22

Lept

oII_

scaf

f_12

0_G

EN

E_4

efflu

x pr

otei

n42

1027

2743

.319

.33

10.6

36.3

316

.56

22

Lept

oII_

scaf

f_12

0_G

EN

E_5

tyro

syl t

RN

A s

ynth

etas

e46

7.2

105

105

23.1

10.0

316

.53

12.4

69.

22

2Le

ptoI

I_sc

aff_

120_

GE

NE

_6un

ique

hyp

othe

tical

469.

29.

11.

65.

262.

262

2Le

ptoI

I_sc

aff_

120_

GE

NE

_7nu

cleo

side

dip

hosp

hate

kin

ase

169

4242

76.8

62.1

62.3

37.

2352

.43

64.5

22

Lept

oII_

scaf

f_12

0_G

EN

E_9

dTD

P-g

luco

se 4

-6-d

ehyd

rata

se

336

9696

29.1

2.46

12.2

39.

82

Lept

oII_

scaf

f_13

_GE

NE

_11

flage

llar p

rote

in F

liS17

5.9

1010

14.5

4.83

22

Lept

oII_

scaf

f_13

_GE

NE

_12

flage

llar h

ook-

asso

ciat

ed p

rote

in52

726

2452

21.2

619

.63

13.0

617

.36.

22

2Le

ptoI

I_sc

aff_

13_G

EN

E_1

3fla

gelli

n30

1051

5186

.269

.43

65.1

67.7

662

.66

57.5

2Le

ptoI

I_sc

aff_

13_G

EN

E_1

4co

nser

ved

hypo

thet

ical

165.

115

22.4

4.66

5.13

22

Lept

oII_

scaf

f_13

_GE

NE

_15

uniq

ue h

ypot

hetic

al

98

756

.27.

9312

.515

.86

43.8

22

Lept

oII_

scaf

f_13

_GE

NE

_16

flage

llar h

ook-

asso

ciat

ed p

rote

in35

1017

58.7

34.6

328

.03

9.3

19.1

252

2Le

ptoI

I_sc

aff_

13_G

EN

E_1

7fla

gella

r hoo

k as

soci

ated

pro

tein

616.

936

3640

.522

.316

.86

12.6

112

2Le

ptoI

I_sc

aff_

13_G

EN

E_1

9un

ique

hyp

othe

tical

1310

427

.712

.33

15.1

3.06

18.5

22

Lept

oII_

scaf

f_13

_GE

NE

_20

flage

llin

316

4343

4339

.66

40.6

40.8

36.6

282

2Le

ptoI

I_sc

aff_

13_G

EN

E_2

2fla

gella

r P-r

ing

prot

ein

3810

5555

3513

.56

12.6

33.

25.

15.

12

Lept

oII_

scaf

f_13

_GE

NE

_23

uniq

ue h

ypot

hetic

al (s

imila

r to

flage

llar L

-rin

g pr

otei

n Fl

gH)

2310

329

.314

.14

4.63

2Le

ptoI

I_sc

aff_

13_G

EN

E_2

5fla

gella

r hoo

k ba

sal-b

ody

prot

ein

FlgG

286

6969

52.1

18.6

618

.427

.83

14.2

2Le

ptoI

I_sc

aff_

13_G

EN

E_2

6fla

gella

r bio

synt

hesi

s pr

otei

n29

8.1

3636

13.5

4.5

22

Lept

oII_

scaf

f_13

_GE

NE

_27

cate

chol

pat

hway

aci

d hy

drat

ase

286

6060

4117

.73

16.8

631

.822

.22

2Le

ptoI

I_sc

aff_

13_G

EN

E_2

8di

hydr

odip

icol

inat

e re

duct

ase

276

5050

44.7

30.4

319

.63

31.8

636

22

Lept

oII_

scaf

f_13

_GE

NE

_29

dihy

drod

ipic

olin

ate

synt

hase

316

8383

75.9

48.4

56.4

362

.53

52.8

22

Lept

oII_

scaf

f_13

_GE

NE

_30

uniq

ue h

ypot

hetic

al18

540

24.4

320

192

2Le

ptoI

I_sc

aff_

13_G

EN

E_3

1di

amin

opim

elat

e de

carb

oxyl

ase

456

126

126

67.4

47.8

344

.86

19.8

649

.33

31.6

22

Lept

oII_

scaf

f_13

_GE

NE

_32

argi

nosu

ccin

ate

lyas

e53

612

512

041

.518

.13

26.2

19.9

32

2Le

ptoI

I_sc

aff_

13_G

EN

E_3

3ar

gino

succ

inat

e sy

ntha

se45

614

114

163

.743

.46

47.1

338

.23

40.7

2Le

ptoI

I_sc

aff_

13_G

EN

E_3

4or

nith

ine

carb

amoy

ltran

sfer

ase

356.

283

8234

.67.

3616

.42

2Le

ptoI

I_sc

aff_

13_G

EN

E_3

5N

-ace

tylo

rnith

ine

amin

otra

nsfe

rase

436.

198

9825

.64.

216

.76

3.16

12.6

22

Lept

oII_

scaf

f_13

_GE

NE

_36

pota

ssiu

m u

ptak

e pr

otei

n38

660

4940

.124

.66

31.2

324

.03

28.2

22

Lept

oII_

scaf

f_13

_GE

NE

_37

perm

ease

509

8080

12.2

9.73

8.26

2.83

5.4

2Le

ptoI

I_sc

aff_

13_G

EN

E_4

uniq

ue h

ypot

hetic

al24

4.6

28.1

9.36

22

Lept

oII_

scaf

f_13

_GE

NE

_42

uniq

ue h

ypot

hetic

al19

542

.45.

538

.46

27.8

325

.32

2Le

ptoI

I_sc

aff_

13_G

EN

E_4

3Fe

-S o

xido

redu

ctas

e 60

911

612

39.6

16.2

326

.03

16.3

69.

22

2Le

ptoI

I_sc

aff_

13_G

EN

E_4

5un

ique

hyp

othe

tical

355

24.6

15.4

67.

84.

42.

632

2Le

ptoI

I_sc

aff_

13_G

EN

E_5

0rib

ose-

5-ph

osph

ate

isom

eras

e17

638

3859

.536

.46

27.6

339

.43

35.4

22

Lept

oII_

scaf

f_13

_GE

NE

_51

glyc

ine

hydr

oxym

ethy

ltran

sfer

ase

457

149

149

44.2

23.7

628

.66

22.3

21.5

22

Lept

oII_

scaf

f_13

_GE

NE

_58

Thio

l:dis

ulfid

e in

terc

hang

e pr

otei

n tlp

A/c

yt c

bio

gene

sis

239

2222

24.1

15.5

623

.66.

532

2Le

ptoI

I_sc

aff_

13_G

EN

E_6

0cy

toch

rom

e bi

osyn

thes

is p

rote

in C

cs1/

Res

B58

9.6

9637

13.9

5.33

8.53

22

Lept

oII_

scaf

f_13

_GE

NE

_61

AB

C tr

ansp

orte

r59

929

2135

19.1

317

.33

12.0

32

2Le

ptoI

I_sc

aff_

13_G

EN

E_6

2A

BC

tran

spor

ter

297

6060

16.3

13.5

2Le

ptoI

I_sc

aff_

13_G

EN

E_6

4al

anin

e ra

cem

ase

455.

852

5014

7.16

22

Lept

oII_

scaf

f_13

_GE

NE

_65

ribos

ome

recy

clin

g fa

ctor

219

4242

629.

063.

6346

.93

42.6

41.8

22

Lept

oII_

scaf

f_13

_GE

NE

_66

urid

ylat

e ki

nase

266.

980

8058

.130

.96

3626

.86

19.5

22

Lept

oII_

scaf

f_13

_GE

NE

_67

trans

latio

n el

onga

tion

fact

or E

F-Ts

226

5050

85.4

66.9

660

.151

.36

7047

22

Lept

oII_

scaf

f_13

_GE

NE

_68

ribos

omal

pro

tein

S2

(426

-7, 1

3-68

)29

778

7879

.961

.561

.66

60.2

67.2

2Le

ptoI

I_sc

aff_

13_G

EN

E_8

glyc

osyl

trans

fera

se89

526

145.

51.

832

2Le

ptoI

I_sc

aff_

134_

GE

NE

_10

phos

phat

e st

arva

tion-

indu

cibl

e pr

otei

n ph

oB37

784

8230

.25.

2320

.53

3.73

22

Lept

oII_

scaf

f_13

4_G

EN

E_1

1un

ique

hyp

othe

tical

(sim

ilar t

o un

iver

sal s

tress

pro

tein

)20

69

915

.25.

0610

.13

22

Lept

oII_

scaf

f_13

4_G

EN

E_1

3un

ique

hyp

othe

tical

(410

-3, 1

34-1

3)12

840

18.4

25.4

30.4

620

2Le

ptoI

I_sc

aff_

134_

GE

NE

_14

UD

P-g

alac

tose

-lipi

d ca

rrie

r tra

nsfe

rase

(410

-4, 1

34-1

4)27

8.9

5831

35.5

5.4

8.4

22

Lept

oII_

scaf

f_13

4_G

EN

E_1

5pr

otei

n di

sulfi

de is

omer

ase

(134

-15,

410

-5)

226

1010

70.2

46.3

38.5

370

.253

.73

35.4

22

Lept

oII_

scaf

f_13

4_G

EN

E_2

thia

min

e bi

osyn

thes

is p

rote

in (6

6-1,

134

-2)

516

017

957

.419

.76

36.1

616

.811

.72

Lept

oII_

scaf

f_13

4_G

EN

E_3

Clp

pro

teas

e A

TP-b

indi

ng s

ubun

it11

68.

516

124.

71.

562

2Le

ptoI

I_sc

aff_

134_

GE

NE

_4ex

conu

clea

se A

BC

sub

unit

C

729

116

116

4.5

1.5

0.9

22

Lept

oII_

scaf

f_13

4_G

EN

E_7

cell

divi

sion

pro

tein

Fts

Y34

7.9

6666

48.9

22.1

28.4

633

.116

.82

Lept

oII_

scaf

f_13

5_G

EN

E_1

0sh

ort c

hain

deh

ydro

gena

se26

675

4810

.810

.82

2Le

ptoI

I_sc

aff_

135_

GE

NE

_11

gluc

ose

6-ph

osph

ate

dehy

drog

enas

e (s

imila

r to

295-

1)

536

136

136

38.9

16.3

625

.514

.96

22

Lept

oII_

scaf

f_13

5_G

EN

E_1

26-

phos

phog

luco

nate

deh

ydro

gena

se (1

35-1

2, 2

95-2

)37

612

812

833

.923

.56

27.2

327

.43

13.3

22

Lept

oII_

scaf

f_13

5_G

EN

E_2

GTP

-bin

ding

pro

tein

/pho

spho

glyc

erat

e de

hydr

ogen

ase

539.

689

7930

.55.

4612

.83

7.1

22

Lept

oII_

scaf

f_13

5_G

EN

E_3

phos

phoe

nolp

yruv

ate

synt

hase

896

00

70.7

49.4

52.8

41.5

637

.22

Lept

oII_

scaf

f_13

5_G

EN

E_6

N-a

cety

lglu

tam

ate

synt

hase

496.

610

610

614

.31.

862.

462.

062

2Le

ptoI

I_sc

aff_

135_

GE

NE

_8m

ethy

l-acc

eptin

g ch

emot

axis

pro

tein

647

2222

5132

.53

39.5

620

.83

14.6

22

Lept

oII_

scaf

f_13

5_G

EN

E_9

cons

erve

d hy

poth

etic

al (s

imila

r to

SA

M-d

epen

dent

met

hyltr

ans

385.

812

523

.84.

739.

536.

962

2Le

ptoI

I_sc

aff_

137_

GE

NE

_1(7

13-1

, 137

-1, s

imila

r to

527-

1, 2

71-1

) tra

nsla

tion

elon

gatio

n f a

445.

80

090

.776

.66

73.2

15.0

671

.574

.42

2Le

ptoI

I_sc

aff_

137_

GE

NE

_2tra

nscr

iptio

n an

titer

min

atio

n21

544

4460

.323

.925

.751

.26

51.6

22

Lept

oII_

scaf

f_13

7_G

EN

E_3

ribos

omal

pro

tein

L11

(137

-3, 6

40-4

)15

1045

4568

.129

.341

.83

20.3

355

.148

.22

2Le

ptoI

I_sc

aff_

137_

GE

NE

_4rib

osom

al p

rote

in L

1 25

971

7180

.260

.03

60.9

34.

4669

.56

71.6

22

Lept

oII_

scaf

f_13

7_G

EN

E_5

ribos

omal

pro

tein

L10

1910

1818

74.1

46.9

351

.33

2255

.93

64.4

22

Lept

oII_

scaf

f_13

7_G

EN

E_6

ribos

omal

pro

tein

, L7/

L12

135

1919

93.8

76.3

81.2

378

.36

93.8

93.8

22

Lept

oII_

scaf

f_13

7_G

EN

E_7

RN

A p

olym

eras

e be

ta s

ubun

it19

36

00

67.8

40.7

354

.632

.13

27.9

22

Lept

oII_

scaf

f_13

7_G

EN

E_8

RN

A p

olym

eras

e

176

70

063

.130

.16

43.9

30.

4322

.96

23.1

22

Lept

oII_

scaf

f_14

_GE

NE

_10

trans

crip

tiona

l reg

ulat

or16

9.6

1916

39.5

4.53

11.5

611

.12

2Le

ptoI

I_sc

aff_

14_G

EN

E_1

1N

AD

H:fl

avin

oxi

dore

duct

ase

406

126

126

57.5

45.4

338

36.8

651

.52

Lept

oII_

scaf

f_14

_GE

NE

_19

sigm

a-54

dep

ende

nt D

NA

-bin

ding

tran

scrip

tiona

l reg

ulat

or52

8.7

104

993.

91.

32

Lept

oII_

scaf

f_14

_GE

NE

_2

(51-

6, 1

4-2)

GG

DE

F do

mai

n pr

otei

n36

5.4

9793

7.1

2.4

22

Lept

oII_

scaf

f_14

_GE

NE

_20

uniq

ue h

ypot

hetic

al (l

ike

Fe/P

b pe

rmea

se, c

ytoc

hrom

e c)

= c

yt19

66

667

5.4

15.7

65.2

16.9

5.4

Lept

oII_

scaf

f_14

_GE

NE

_20S

NP

114

_GE

NE

_20

(abo

ve) w

ith A

B-e

nd b

iofil

m v

aria

nt s

eque

nce

100

20.9

15.5

100

31.1

637

.32

2Le

ptoI

I_sc

aff_

14_G

EN

E_2

2un

ique

hyp

othe

tical

168

59.6

31.7

338

.824

.66

22

Lept

oII_

scaf

f_14

_GE

NE

_24

enol

ase

465

137

137

48.9

32.6

36.7

626

.618

.3

22

Lept

oII_

scaf

f_14

_GE

NE

_26

uniq

ue h

ypot

hetic

al26

1152

.99.

2316

.03

42.6

11.7

614

.52

2Le

ptoI

I_sc

aff_

14_G

EN

E_2

7gl

utam

yl-tR

NA

(Gln

) am

idot

rans

fera

se56

613

413

438

.614

.36

25.3

9.46

22

Lept

oII_

scaf

f_14

_GE

NE

_28

glut

amyl

-tRN

A a

mid

otra

nsfe

rase

536

129

129

37.8

16.2

23.6

7.43

4.7

22

Lept

oII_

scaf

f_14

_GE

NE

_29

aspa

rtate

dec

arbo

xyla

se13

831

3160

.331

.43

33.0

617

.939

.36

382

2Le

ptoI

I_sc

aff_

14_G

EN

E_3

NA

DP

-red

ucin

g hy

drog

enas

e, s

ubun

it C

/NA

DH

deh

ydro

gena

se69

610

810

835

.915

.63

15.8

38.

19.

92

2Le

ptoI

I_sc

aff_

14_G

EN

E_3

0gl

utam

yl-tR

NA

(Gln

) am

idot

rans

fera

se, C

sub

unit

155.

813

1321

.921

.92

Lept

oII_

scaf

f_14

_GE

NE

_31

ATP

-dep

ente

nd D

NA

hel

icas

e84

912

012

05.

91.

962

2Le

ptoI

I_sc

aff_

14_G

EN

E_3

2un

ique

hyp

othe

tical

(Tol

B-li

ke)

516

33

69.5

42.4

652

.16

38.5

622

.12

2Le

ptoI

I_sc

aff_

14_G

EN

E_3

3gl

ucos

amin

e--fr

ucto

se-6

-pho

spha

te a

min

otra

nsfe

rase

665.

513

012

538

.712

.93

21.1

67

22

Lept

oII_

scaf

f_14

_GE

NE

_34

UD

P-N

-ace

tylg

luco

sam

ine

pyro

phos

phor

ylas

e50

6.3

8380

29.9

10.6

12.8

61.

0610

.12

Lept

oII_

scaf

f_14

_GE

NE

_35

trans

porte

r25

928

1231

.517

.719

.812

.62

Lept

oII_

scaf

f_14

_GE

NE

_37

lact

oylg

luta

thio

ne ly

ase

175.

145

1815

.815

.85.

2610

.32

2Le

ptoI

I_sc

aff_

14_G

EN

E_3

8tra

nscr

iptio

nal r

egul

ator

in a

rsen

ic re

sist

ance

ope

ron

136.

617

1751

.35.

1310

.26

27.3

62

2Le

ptoI

I_sc

aff_

14_G

EN

E_4

uniq

ue h

ypot

hetic

al23

930

26.1

25.8

17.8

62

Lept

oII_

scaf

f_14

_GE

NE

_42

cons

erve

d hy

poth

etic

al (g

luta

mat

e sy

nthe

tase

-like

) 8

913

55.3

7.9

14.0

32

Lept

oII_

scaf

f_14

_GE

NE

_46

hydr

olas

e/2,

3-di

keto

-5-m

ethy

lthio

-1-p

hosp

hope

ntan

e ph

osph

a t25

5.4

3418

7.9

2.63

2Le

ptoI

I_sc

aff_

14_G

EN

E_4

8ox

idas

e 21

538

1413

.44.

462

2Le

ptoI

I_sc

aff_

14_G

EN

E_4

9pe

roxi

redo

xin

226

6868

40.5

21.8

330

.16

27.5

16.5

22

Lept

oII_

scaf

f_14

_GE

NE

_50

cyto

chro

me

c pe

roxi

dase

3710

6565

3726

.63

24.0

621

.522

.229

.32

2Le

ptoI

I_sc

aff_

14_G

EN

E_5

3th

ymid

ylat

e ki

nase

25

637

3518

.62.

1310

.63

2Le

ptoI

I_sc

aff_

14_G

EN

E_5

4D

NA

pol

ymer

ase

III g

amm

a su

buni

t38

5.8

2121

93

2Le

ptoI

I_sc

aff_

14_G

EN

E_5

5si

gnal

pep

tidas

e II

309.

136

3226

.74.

068.

92

2Le

ptoI

I_sc

aff_

14_G

EN

E_5

6m

ethi

onyl

-tRN

A s

ynth

etas

e 75

616

215

835

.27.

917

.26

5.1

8.5

2Le

ptoI

I_sc

aff_

14_G

EN

E_6

6am

ino

acid

tran

spor

ter (

14-6

6, 1

087-

1)71

9.6

6733

8.1

1.53

3.1

2Le

ptoI

I_sc

aff_

14_G

EN

E_6

7N

AD

H d

ehyd

roge

nase

/pyr

idin

e nu

cleo

tide-

disu

lfide

oxi

dore

duc

519.

463

617.

55

22

Lept

oII_

scaf

f_14

_GE

NE

_8ph

osph

oglu

cosa

min

e m

utas

e50

6.1

130

127

38.9

3.5

17.5

5.46

22

Lept

oII_

scaf

f_14

0_G

EN

E_1

cold

sho

ck p

rote

in18

618

1889

.788

.23

80.9

77.9

389

.789

.72

Lept

oII_

scaf

f_14

0_G

EN

E_2

uniq

ue h

ypot

hetic

al25

108

1717

2Le

ptoI

I_sc

aff_

140_

GE

NE

_5re

plic

ativ

e D

NA

hel

icas

e52

5.6

111

109

31.7

15.7

32.

32

Lept

oII_

scaf

f_14

0_G

EN

E_6

hist

idyl

-tRN

A s

ynth

etas

e44

5.6

3223

25.3

4.43

8.86

9.2

22

Lept

oII_

scaf

f_14

0_G

EN

E_7

phos

phog

lyce

rate

deh

ydro

gena

se58

613

713

774

62.1

664

.86

2.23

62.9

657

.82

2Le

ptoI

I_sc

aff_

140_

GE

NE

_8am

inot

rans

fera

se41

997

9760

.941

.36

51.5

343

.83

32.3

2Le

ptoI

I_sc

aff_

140_

GE

NE

_9ol

igop

eptid

e-bi

ndin

g pr

otei

n O

ppA

3910

3939

19.2

3.8

2.63

22

Lept

oII_

scaf

f_14

1_G

EN

E_1

uniq

ue h

ypot

hetic

al (1

41-1

, 8-7

0)27

67

89.5

48.0

338

.676

.551

.23

30.5

22

Lept

oII_

scaf

f_14

1_G

EN

E_2

uniq

ue h

ypot

hetic

al48

95

33.3

30.3

28.8

10.3

622

.521

.22

2Le

ptoI

I_sc

aff_

141_

GE

NE

_3ou

ter m

embr

ane

prot

ein

Om

pA29

1046

1977

.472

.06

62.8

52.6

65.5

364

.92

Lept

oII_

scaf

f_14

1_G

EN

E_7

cons

erve

d hy

poth

etic

al14

5.5

751.

80.

62

Lept

oII_

scaf

f_14

7_G

EN

E_1

4G

GD

EF

dom

ain

prot

ein

(147

-14,

3-1

05, 3

-106

)42

5.7

2222

222.

736.

967.

332

2Le

ptoI

I_sc

aff_

147_

GE

NE

_15

carb

onic

anh

ydra

se (3

-104

, 147

-15)

218

7619

9.3

2.23

7.56

22

Lept

oII_

scaf

f_14

7_G

EN

E_2

cons

erve

d hy

poth

etic

al (p

redi

cted

tran

scrip

tiona

l reg

ulat

or)

107

3169

.119

.23

30.9

343

.63

22

Lept

oII_

scaf

f_14

7_G

EN

E_3

cons

erve

d hy

poth

etic

al

139.

735

37.5

24.1

19.6

32

Lept

oII_

scaf

f_14

7_G

EN

E_7

alco

hol d

ehyd

roge

nase

378.

686

7115

.83.

933.

3310

2Le

ptoI

I_sc

aff_

150_

GE

NE

_13

inne

r mem

bran

e pr

otei

n, 6

0 kD

a/pr

epro

tein

tran

sloc

ase

589.

470

6718

.45.

838.

932.

12

2Le

ptoI

I_sc

aff_

150_

GE

NE

_15

ribos

omal

pro

tein

L9

(429

-3, 1

50-1

5)17

920

2061

.343

.144

.925

.13

52.2

61.3

22

Lept

oII_

scaf

f_15

0_G

EN

E_4

ribon

ucle

ase

III42

529

2927

.713

.66

14.8

33.

220

.36

12.5

2Le

ptoI

I_sc

aff_

150_

GE

NE

_5D

NA

pol

ymer

ase

III (a

lpha

sub

unit)

305.

523

2121

.95.

263.

262

Lept

oII_

scaf

f_15

0_G

EN

E_6

tRN

A(5

-met

hyla

min

omet

hyl-2

-thio

urid

ylat

e)-m

ethy

l tra

nsfe

ras e

428.

149

456.

82.

262

2Le

ptoI

I_sc

aff_

150_

GE

NE

_7co

nser

ved

hypo

thet

ical

146

1678

51.2

631

.83

76.5

331

.12

2Le

ptoI

I_sc

aff_

150_

GE

NE

_8ch

rom

osom

e pa

rtion

ing

prot

ein,

Par

B27

931

3140

.313

.316

.232

.915

2Le

ptoI

I_sc

aff_

150_

GE

NE

_9sp

orul

atio

n in

itiat

ion

inhi

bito

r/ATP

ase

Par

A28

5.8

7268

33.9

5.5

19.1

313

.916

.12

2Le

ptoI

I_sc

aff_

167_

GE

NE

_10

N-a

cety

l am

idas

e (1

67-1

0, 7

75-4

)49

1143

4310

.83.

834.

067.

262

Lept

oII_

scaf

f_16

7_G

EN

E_2

ATP

-dep

ende

nt D

NA

hel

icas

e74

5.5

100

9614

.81.

965.

72

Lept

oII_

scaf

f_16

7_G

EN

E_3

DN

A p

olym

eras

e III

, alp

ha s

ubun

it13

56

00

61.

031.

232

Lept

oII_

scaf

f_16

7_G

EN

E_4

carb

oxyl

tran

sfer

ase,

alp

ha s

ubun

it 33

680

7820

.33.

615

.92

Lept

oII_

scaf

f_16

7_G

EN

E_5

trypt

opha

nyl-t

RN

A s

ynth

etas

e40

6.3

111

111

20.7

9.93

22

Lept

oII_

scaf

f_16

7_G

EN

E_7

uniq

ue h

ypot

hetic

al (s

imila

r to

bran

ched

cha

in a

min

o ac

id tr

ans

747

77

23.6

10.2

8.73

17.8

313

.78.

72

Lept

oII_

scaf

f_17

0_G

EN

E_1

4co

nser

ved

hypo

thet

ical

(170

-14,

294

-8)

425.

528

4.4

1.46

2Le

ptoI

I_sc

aff_

170_

GE

NE

_5m

obili

zatio

n pr

otei

n Tr

aI12

76.

798

983.

33.

32

Lept

oII_

scaf

f_17

0_G

EN

E_7

Trw

B p

lasm

id p

rote

in75

8.6

4848

6.4

2.13

22

Lept

oII_

scaf

f_17

3_G

EN

E_1

4un

ique

hyp

othe

tical

695.

936

21.4

624

.21.

1610

.26

2Le

ptoI

I_sc

aff_

173_

GE

NE

_15

trans

posa

se (1

73-1

5, 2

61-8

, 265

-11,

412

-1, 2

61-1

)49

1013

812

710

.93.

631.

462

2Le

ptoI

I_sc

aff_

173_

GE

NE

_16

trans

posa

se (7

3-38

, 173

-16,

412

-2, 2

65-1

0, 2

61-9

)25

538

3771

.434

.13

30.2

54.4

337

.12

Lept

oII_

scaf

f_17

3_G

EN

E_2

uniq

ue h

ypot

hetic

al8

1220

.56.

832

2Le

ptoI

I_sc

aff_

173_

GE

NE

_9un

ique

hyp

othe

tical

4010

13.1

5.56

4.23

1.5

5.56

102

2Le

ptoI

I_sc

aff_

174_

GE

NE

_10

imid

azol

egly

cero

l pho

spha

te d

ehyd

roge

nase

236

5555

62.9

21.4

351

.43

57.7

657

.62

2Le

ptoI

I_sc

aff_

174_

GE

NE

_11

amid

otra

nsfe

rase

His

H23

646

4036

5.83

17.8

618

.328

22

Lept

oII_

scaf

f_17

4_G

EN

E_1

2ph

osph

orib

osyl

form

imin

o-5-

amin

oim

idaz

ole

isom

eras

e27

652

5266

.418

.23

15.1

324

.96

22

Lept

oII_

scaf

f_17

4_G

EN

E_1

3H

isF

(cyc

lase

)27

680

8048

.214

.528

.36

26.9

312

.92

Lept

oII_

scaf

f_17

4_G

EN

E_1

4ph

osph

orib

osyl

-AM

P c

yclo

hydr

olas

e, H

isI

245.

844

4424

.74.

18.

962

2Le

ptoI

I_sc

aff_

174_

GE

NE

_15

HIT

fam

ily h

ydro

lase

137

2525

8918

.36

64.6

652

.23

74.6

22

Lept

oII_

scaf

f_17

4_G

EN

E_1

6pr

okar

yotic

his

tone

-like

dom

ain

1111

1313

83.3

49.7

69.9

364

.36

70.9

64.7

22

Lept

oII_

scaf

f_17

4_G

EN

E_2

trans

crip

tion

term

inat

ion

fact

or47

617

117

188

.946

.73

67.0

355

.63

42.5

22

Lept

oII_

scaf

f_17

4_G

EN

E_3

ribos

omal

pro

tein

L31

89

1717

70.6

40.6

644

.622

.53

60.8

70.6

22

Lept

oII_

scaf

f_17

4_G

EN

E_4

pept

ide

chai

n re

leas

e fa

ctor

141

694

9442

.48.

522

.73

14.9

311

.12

2Le

ptoI

I_sc

aff_

174_

GE

NE

_6U

DP

-N-a

cety

lglu

cosa

min

e 1-

carb

oxyv

inyl

trans

fera

se47

6.3

110

108

43.9

11.0

329

.26

6.56

22

Lept

oII_

scaf

f_17

4_G

EN

E_7

ATP

pho

spho

ribos

yltra

nsfe

rase

(his

tidin

e b

iosy

nthe

sis)

247.

945

4566

.512

.936

.96

3.13

30.8

324

.52

2Le

ptoI

I_sc

aff_

174_

GE

NE

_8hi

stid

inol

deh

ydro

gena

se

485

9696

30.8

13.7

11.4

6.3

2Le

ptoI

I_sc

aff_

174_

GE

NE

_9hi

stod

inol

am

inot

rans

fera

se40

654

5251

20.5

327

.46

17.4

32

Lept

oII_

scaf

f_17

5_G

EN

E_1

3un

ique

hyp

othe

tical

439

40.2

15.2

311

.36

8.96

8.96

22

Lept

oII_

scaf

f_17

5_G

EN

E_1

4co

nser

ved

hypo

thet

ical

(175

-14,

294

-2)

485

2940

.45.

3325

.33

8.66

22

Lept

oII_

scaf

f_17

5_G

EN

E_2

cons

erve

d hy

poth

etic

al (1

75-2

, 104

5-3)

1810

4029

.720

.83

8.06

16.7

62

2Le

ptoI

I_sc

aff_

175_

GE

NE

_4ph

opho

glyc

erat

e m

utas

e25

658

5884

.334

.53

46.5

59.6

346

.22

Lept

oII_

scaf

f_17

5_G

EN

E_6

two-

com

pone

nt re

spon

se re

gula

tor (

HD

-GY

P d

omai

n co

ntai

nin

476.

537

1613

.63.

232.

332

Lept

oII_

scaf

f_17

5_G

EN

E_8

glyc

ogen

deb

ranc

hing

enz

yme

816.

10

07.

12.

362

2Le

ptoI

I_sc

aff_

175_

GE

NE

_9un

ique

hyp

othe

tical

1611

30.8

25.4

32

Lept

oII_

scaf

f_17

8_G

EN

E_1

Zn-d

epen

dent

hyd

rola

se26

5.5

8542

15.6

5.2

2Le

ptoI

I_sc

aff_

178_

GE

NE

_2un

ique

hyp

othe

tical

(sim

ilar t

o tra

nscr

iptio

nal r

egul

ator

s)13

9.3

937

22.1

32

2Le

ptoI

I_sc

aff_

178_

GE

NE

_6m

etal

ion

efflu

x pr

otei

n50

922

1245

.130

.03

34.8

316

.63

16.3

22

Lept

oII_

scaf

f_17

8_G

EN

E_7

efflu

x sy

stem

tran

smem

bran

e pr

otei

n46

1163

4549

.417

.26

29.8

324

.525

.32

2Le

ptoI

I_sc

aff_

178_

GE

NE

_8ca

tion

efflu

x sy

stem

tran

smem

bran

e pr

otei

n11

610

00

26.1

6.8

8.83

2.36

32

2Le

ptoI

I_sc

aff_

178_

GE

NE

_9un

ique

hyp

othe

tical

1410

938

.838

.822

.92

2Le

ptoI

I_sc

aff_

183_

GE

NE

_1ac

etol

acta

te s

ynth

ase

(183

-1, 2

6-33

)23

978

7648

.429

.26

33.3

325

.36

16.9

22

Lept

oII_

scaf

f_18

3_G

EN

E_2

chro

mos

omal

repl

icat

ion

initi

ator

pro

tein

Dna

A (s

imila

r to

26-3

253

8.7

101

9926

.94.

3613

.15.

32

2Le

ptoI

I_sc

aff_

183_

GE

NE

_3D

NA

pol

ymer

ase

III (s

imila

r to

26-3

1)43

527

2559

.730

.66

37.5

631

.36

25.1

22

Lept

oII_

scaf

f_18

3_G

EN

E_4

DN

A g

yras

e, B

sub

unit

(sim

ilar t

o 26

-30)

926

00

29.5

9.43

17.9

4.1

10.3

22

Lept

oII_

scaf

f_18

3_G

EN

E_5

DN

A g

yras

e, A

sub

unit

(sim

ilar t

o 26

-29)

906

00

31.7

13.7

615

.03

7.33

5.8

22

Lept

oII_

scaf

f_18

3_G

EN

E_6

uniq

ue h

ypot

hetic

al (1

83-6

, 26-

28)

309

554

.241

.241

.06

10.6

32.7

312

Lept

oII_

scaf

f_18

3_G

EN

E_8

Exs

B p

rote

in (s

imila

r to

26-2

6)26

762

6225

.34.

569.

1311

.46

22

Lept

oII_

scaf

f_18

3_G

EN

E_9

amin

opep

tidas

e (s

imila

r to

26-2

5, 1

32-1

)58

8.6

9494

36.7

18.4

624

.23

18.6

616

.22

2Le

ptoI

I_sc

aff_

185_

GE

NE

_13

uniq

ue h

ypot

hetic

al18

65

93.5

34.1

644

.93

81.0

661

.06

56.1

22

Lept

oII_

scaf

f_18

5_G

EN

E_1

5bi

opol

ymer

tran

spor

t16

618

1853

.134

.723

.93

15.8

613

.82

2Le

ptoI

I_sc

aff_

185_

GE

NE

_16

cons

erve

d hy

poth

etic

al (s

imila

r to

perip

lasm

ic p

rote

in T

onB

, li n

167

106

76.8

22.0

623

.776

.848

.640

.82

2Le

ptoI

I_sc

aff_

185_

GE

NE

_18

biop

olym

er tr

ansp

ort

267

3431

44.1

35.4

342

.06

22.3

310

.62

2Le

ptoI

I_sc

aff_

185_

GE

NE

_19

uniq

ue h

ypot

hetic

al56

526

.216

.93

20.3

313

.53

13.8

62

Lept

oII_

scaf

f_18

5_G

EN

E_2

2co

nser

ved

hypo

thet

ical

30

9.9

1135

.66.

8318

.92

Lept

oII_

scaf

f_18

5_G

EN

E_9

uniq

ue h

ypot

hetic

al5

1271

.123

.715

.56

22

Lept

oII_

scaf

f_18

6_G

EN

E_1

2un

ique

hyp

othe

tical

136.

422

.47.

462

Lept

oII_

scaf

f_18

6_G

EN

E_1

3un

ique

hyp

othe

tical

(sim

ilar t

o O

-link

ed G

lcN

Ac

trans

fera

se)

125.

26

534

.514

.53

12.1

38.

534

.52

2Le

ptoI

I_sc

aff_

186_

GE

NE

_2un

ique

hyp

othe

tical

(sim

ilar t

o su

lfur t

rans

fer p

rote

in in

thia

min

e8

58

658

.613

.33

58.6

58.6

22

Lept

oII_

scaf

f_18

6_G

EN

E_3

gene

ral s

ecre

tion

path

way

pro

tein

C (1

86-3

, 710

-8)

359.

519

196.

52.

162

2Le

ptoI

I_sc

aff_

186_

GE

NE

_4G

spD

, gen

eral

sec

reto

ry p

rote

in (1

86-4

, 113

6-3)

5810

3636

41.7

6.2

22.3

39.

75.

32

2Le

ptoI

I_sc

aff_

186_

GE

NE

_5ge

nera

l sec

retio

n pa

thw

ay p

rote

in E

636

135

133

16.1

1.76

5.83

2Le

ptoI

I_sc

aff_

186_

GE

NE

_6fim

bria

l ass

embl

y pr

otei

n/ge

nera

l sec

retio

n pa

thw

ay p

rote

in F

449.

362

6224

17.6

2Le

ptoI

I_sc

aff_

186_

GE

NE

_7ge

nera

l sec

reto

ry p

athw

ay p

rote

in G

188.

847

4660

.429

.16

42.5

347

.82

2Le

ptoI

I_sc

aff_

186_

GE

NE

_8un

ique

hyp

othe

tical

3810

431

.911

.73.

1319

.712

.12

2Le

ptoI

I_sc

aff_

191_

GE

NE

_3un

ique

hyp

othe

tical

6510

27.2

15.9

311

.12.

162

2Le

ptoI

I_sc

aff_

191_

GE

NE

_4gl

ucos

e-6-

phos

phat

e de

hydr

ogen

ase

(sim

ilar t

o 53

-18)

566

125

122

47.9

19.4

325

.06

13.2

68.

12

2Le

ptoI

I_sc

aff_

191_

GE

NE

_5tra

nsal

dola

se10

66

135

135

63.9

33.8

639

.33

24.9

619

22

Lept

oII_

scaf

f_19

1_G

EN

E_6

trans

keto

lase

526

102

102

66.9

44.5

645

.83

36.9

636

22

Lept

oII_

scaf

f_19

1_G

EN

E_7

trans

posa

se (1

91-7

, 73-

35, 3

74-3

)17

933

3073

.326

.26

12.5

65.

2644

.344

.5

2Le

ptoI

I_sc

aff_

191_

GE

NE

_9re

vers

e tra

nscr

ipta

se34

1092

894.

71.

562

2Le

ptoI

I_sc

aff_

2_G

EN

E_1

0pr

olin

e de

hydr

ogen

ase

317

2424

25.6

11.7

321

.46

7.53

132

Lept

oII_

scaf

f_2_

GE

NE

_100

UD

P-N

-ace

tyle

nolp

yruv

oylg

luco

sam

ine

redu

ctas

e31

5.1

4140

9.9

3.3

2Le

ptoI

I_sc

aff_

2_G

EN

E_1

01U

DP

-N-a

cety

lmur

amat

e--a

lani

ne li

gase

486

118

118

7.2

2.4

0.9

2Le

ptoI

I_sc

aff_

2_G

EN

E_1

02U

DP

-N-a

cety

lglu

cosa

min

e--N

-ace

tylm

uram

yl-(

pent

apep

tide)

py

399.

744

4414

.83.

968.

70.

532.

332

Lept

oII_

scaf

f_2_

GE

NE

_104

UD

P-N

-ace

tylm

uram

oyla

lani

ne--

D-g

luta

mat

e lig

ase

536.

260

5913

.32.

136.

132

2Le

ptoI

I_sc

aff_

2_G

EN

E_1

07U

DP

-N-a

cety

lmur

amoy

lala

nyl-D

-glu

tam

ate-

-2,6

- dia

min

opim

ela

566

9393

26.7

3.2

16.8

35.

36.

12

Lept

oII_

scaf

f_2_

GE

NE

_108

cell

divi

sion

pro

tein

Fts

I63

9.9

9591

41.

332

2Le

ptoI

I_sc

aff_

2_G

EN

E_1

11co

nser

ved

hypo

thet

ical

175

2673

5.63

22.5

345

.26

25.7

2Le

ptoI

I_sc

aff_

2_G

EN

E_1

13un

ique

hyp

othe

tical

219.

724

.423

.35.

362

2Le

ptoI

I_sc

aff_

2_G

EN

E_1

14th

iol-s

peci

fic a

ntio

xida

nt p

rote

in17

727

2793

.589

.76

88.4

385

92.1

691

.52

2Le

ptoI

I_sc

aff_

2_G

EN

E_1

15su

ccin

yl-c

oA s

ynth

etas

e32

696

9646

.930

.927

.56

2.4

33.5

326

.92

2Le

ptoI

I_sc

aff_

2_G

EN

E_1

16su

ccin

yl-c

oA s

ynth

etas

e43

611

811

875

53.3

653

.43

48.4

635

.42

2Le

ptoI

I_sc

aff_

2_G

EN

E_1

17su

ccin

ate

dehy

drog

enas

e59

613

368

47.8

30.8

332

.26

23.7

628

.72

Lept

oII_

scaf

f_2_

GE

NE

_118

cons

erve

d hy

poth

etic

al (s

imila

r to

CO

deh

ydro

gena

se/a

cety

l- C25

5.1

375

7.9

2.63

5.3

22

Lept

oII_

scaf

f_2_

GE

NE

_12

nitro

gen

regu

lato

ry p

rote

in P

-II13

828

2870

.538

.96

45.2

343

.76

53.6

22

Lept

oII_

scaf

f_2_

GE

NE

_120

citra

te s

ynth

ase

309

6767

63.2

40.6

343

.23

53.9

45.4

22

Lept

oII_

scaf

f_2_

GE

NE

_121

acon

itase

697

00

76.6

60.0

364

.76

3.63

58.3

70.5

22

Lept

oII_

scaf

f_2_

GE

NE

_123

succ

inyl

-coA

liga

se35

610

910

976

.859

.23

58.7

66.2

661

.92

2Le

ptoI

I_sc

aff_

2_G

EN

E_1

24su

ccin

yl-c

oA li

gase

237

7777

66.8

49.1

52.7

354

.06

452

2Le

ptoI

I_sc

aff_

2_G

EN

E_1

25tra

nspo

sase

(2-1

25, 2

6-10

, 2-1

28)

2811

2727

35.6

12.1

311

.62

2Le

ptoI

I_sc

aff_

2_G

EN

E_1

26su

ccin

yl-c

oA s

ynth

ase

197

3636

75.6

64.4

340

.260

.851

.82

Lept

oII_

scaf

f_2_

GE

NE

_14

uniq

ue h

ypot

hetic

al17

8.7

11.5

3.83

10.8

62

Lept

oII_

scaf

f_2_

GE

NE

_18

NA

DH

-ubi

quin

one

dehy

drog

enas

e ch

ain

L 70

8.3

137

134

6.9

1.36

20.

932

2Le

ptoI

I_sc

aff_

2_G

EN

E_2

cons

erve

d hy

poth

etic

al14

910

51.2

35.2

28.2

62

2Le

ptoI

I_sc

aff_

2_G

EN

E_2

1N

AD

H d

ehyd

roge

nase

, sub

unit

821

8.1

3333

49.5

39.0

333

.46

25.6

324

.22

Lept

oII_

scaf

f_2_

GE

NE

_22

NA

DH

deh

ydro

gena

se I,

H s

ubun

it 38

688

8817

.57.

811

.32

2Le

ptoI

I_sc

aff_

2_G

EN

E_2

3fo

rmat

e de

hydr

ogen

ase/

Fe3+

redu

ctas

e10

06

119

119

45.4

31.4

29.8

325

.219

.22

2Le

ptoI

I_sc

aff_

2_G

EN

E_2

4N

AD

H d

ehyd

roge

nase

I, F

sub

unit

666

018

041

.311

.46

26.2

311

.36.

22

2Le

ptoI

I_sc

aff_

2_G

EN

E_2

5N

AD

H d

ehyd

roge

nase

195

3535

76.2

36.1

52.7

654

.444

22

Lept

oII_

scaf

f_2_

GE

NE

_26

NA

DH

deh

ydro

gena

se, s

ubun

it D

485.

612

812

836

.426

.06

2516

.23

13.7

22

Lept

oII_

scaf

f_2_

GE

NE

_27

NA

DH

deh

ydro

gena

se s

ubun

it C

225

2727

64.7

2933

43.1

252

2Le

ptoI

I_sc

aff_

2_G

EN

E_2

8N

AD

H d

ehyd

roge

nase

bet

a su

buni

t20

855

5558

.437

.132

40.8

43.3

22

Lept

oII_

scaf

f_2_

GE

NE

_30

prep

rote

in tr

ansl

ocas

e10

35

00

49.6

22.6

627

.717

.86

2Le

ptoI

I_sc

aff_

2_G

EN

E_3

1pe

ptid

ase,

M23

/M37

fam

ily34

6.4

2522

26.6

11.8

311

.42

2Le

ptoI

I_sc

aff_

2_G

EN

E_3

3U

DP

-glu

cose

4-e

pim

eras

e 34

639

3128

.211

.220

.42

2Le

ptoI

I_sc

aff_

2_G

EN

E_3

5de

oxyx

ylul

ose-

5-ph

osph

ate

synt

hase

686.

10

043

.515

.26

28.7

312

.86

92

2Le

ptoI

I_sc

aff_

2_G

EN

E_3

6ge

rany

ltran

stra

nsfe

rase

335.

766

6326

.47.

1610

.33

14.7

318

.82

2Le

ptoI

I_sc

aff_

2_G

EN

E_3

7un

ique

hyp

othe

tical

(exo

nucl

ease

VII-

like)

115

44

48.5

31.6

37.

231

.26

332

Lept

oII_

scaf

f_2_

GE

NE

_39

cons

erve

d hy

poth

etic

al31

5.8

5814

.83.

163.

42

2Le

ptoI

I_sc

aff_

2_G

EN

E_4

0hy

drol

ase

(HA

D s

uper

fam

ily)

586

117

109

46.1

17.3

321

.30.

79.

42

Lept

oII_

scaf

f_2_

GE

NE

_42

uniq

ue h

ypot

hetic

al12

638

.722

.820

.72

Lept

oII_

scaf

f_2_

GE

NE

_43

uniq

ue h

ypot

hetic

al11

1026

.48.

4313

.93

15.4

22

Lept

oII_

scaf

f_2_

GE

NE

_44

solu

ble

lytic

tran

sgly

cosy

lase

77

1017

1424

.211

.56

9.8

6.6

8.9

22

Lept

oII_

scaf

f_2_

GE

NE

_45

TonB

pro

tein

41

1010

1032

.49.

82.

7317

.42

2Le

ptoI

I_sc

aff_

2_G

EN

E_4

7Zn

-dep

ende

nt h

ydro

lase

62

616

513

638

.68.

7313

.96

6.13

62

Lept

oII_

scaf

f_2_

GE

NE

_48

cell

divi

sion

pro

tein

Fts

K

835.

812

212

112

3.1

1.9

22

Lept

oII_

scaf

f_2_

GE

NE

_49

uniq

ue h

ypot

hetic

al (p

utat

ive

oute

r mem

bran

e pr

otei

n)27

105

39.9

14.7

38.2

319

.92

2Le

ptoI

I_sc

aff_

2_G

EN

E_5

uniq

ue h

ypot

hetic

al (s

imila

rto c

hem

otax

is p

rote

in C

heZ)

38

56

538

.44.

8325

.16

8.3

22

Lept

oII_

scaf

f_2_

GE

NE

_50

exci

nucl

ease

AB

C, A

sub

unit

104

80

025

.84.

4611

.06

2.6

22

Lept

oII_

scaf

f_2_

GE

NE

_52

pyrid

oxal

pho

spha

te b

iosy

nthe

sis

376

7171

85.8

62.2

62.2

65.2

360

.52

Lept

oII_

scaf

f_2_

GE

NE

_54

uniq

ue h

ypot

hetic

al24

4.5

17.7

4.9

7.53

22

Lept

oII_

scaf

f_2_

GE

NE

_56

perip

lasm

ic A

BC

tran

spor

ter c

ompo

nent

359.

528

2763

.430

.66

35.9

32.2

68.

92

2Le

ptoI

I_sc

aff_

2_G

EN

E_5

7A

BC

tran

spor

ter,

ATP

-bin

ding

pro

tein

275

4848

37.1

10.1

318

.76

15.8

32

Lept

oII_

scaf

f_2_

GE

NE

_6se

nsor

y bo

x/G

GD

EF

dom

ain/

EA

L do

mai

n pr

otei

n11

76.

113

012

93.

21.

062

2Le

ptoI

I_sc

aff_

2_G

EN

E_6

0U

DP

-glu

cose

4-e

pim

eras

e35

6.6

8278

56.7

19.8

8.96

15.7

620

.72

Lept

oII_

scaf

f_2_

GE

NE

_61

two-

com

pone

nt s

enso

r his

tidin

e ki

nase

507.

963

6220

.15.

7310

.06

1.33

22

Lept

oII_

scaf

f_2_

GE

NE

_62

phos

phat

e re

gulo

n tra

nscr

iptio

n re

gula

tor,

Pho

B26

651

5033

.81.

617

.324

.83

27.3

22

Lept

oII_

scaf

f_2_

GE

NE

_63

met

al-d

epen

dent

pro

teas

e of

the

PA

D1/

JAB

1 su

perfa

mily

186

2150

.911

.03

20.0

611

.86

26.1

619

.62

Lept

oII_

scaf

f_2_

GE

NE

_64

mol

ybdo

pter

in b

iosy

nthe

sis

prot

ein

Moe

B29

6.8

8989

19.9

2.13

4.5

22

Lept

oII_

scaf

f_2_

GE

NE

_65

uniq

ue h

ypot

hetic

al (f

erre

doxi

n-lik

e)9

56

654

.846

.654

.82

2Le

ptoI

I_sc

aff_

2_G

EN

E_6

6co

nser

ved

hypo

thet

ical

(sim

ilar t

o m

olyb

dopt

erin

con

verti

ng fa

c10

624

628

8.96

23.3

328

22

Lept

oII_

scaf

f_2_

GE

NE

_67

thre

onin

e sy

ntha

se46

815

715

680

.845

.26

65.2

55.9

357

.52

2Le

ptoI

I_sc

aff_

2_G

EN

E_6

8th

iam

ine

bios

ynth

esis

pro

tein

Thi

F29

792

8818

.53.

565.

532

2Le

ptoI

I_sc

aff_

2_G

EN

E_6

9cy

stei

ne s

ynth

ase

338

7373

45.2

4.26

20.5

311

.110

.32

Lept

oII_

scaf

f_2_

GE

NE

_7un

ique

hyp

othe

tical

187

410

.83.

62

2Le

ptoI

I_sc

aff_

2_G

EN

E_7

0un

ique

hyp

othe

tical

(sim

ilar t

o Th

iS p

rote

in)

85

84

34.2

17.5

32

2Le

ptoI

I_sc

aff_

2_G

EN

E_7

1S

-ade

nosy

lhom

ocys

tein

e hy

drol

ase

(839

-1, 2

-71)

466

165

165

6237

.943

.76

33.1

620

.82

2Le

ptoI

I_sc

aff_

2_G

EN

E_7

2S

-ade

nosi

nem

ethi

onin

e sy

ntha

se (8

39-2

, 2-7

2)42

613

613

667

54.1

55.6

338

34.8

22

Lept

oII_

scaf

f_2_

GE

NE

_74

uniq

ue h

ypot

hetic

al12

4.8

73.8

56.6

646

.954

.764

.43

53.4

22

Lept

oII_

scaf

f_2_

GE

NE

_75

oxyg

en-in

depe

nden

t cop

ropo

rphy

rinog

en II

53

812

412

238

.615

.26

24.5

4.33

7.6

22

Lept

oII_

scaf

f_2_

GE

NE

_76

erop

orph

yrin

ogen

dec

arbo

xyla

se40

795

9429

.23.

4613

.83

2.8

22

Lept

oII_

scaf

f_2_

GE

NE

_77

cbiX

pro

tein

(cob

alt c

heta

lase

)31

627

1240

.95.

310

.86

37.0

325

.72

Lept

oII_

scaf

f_2_

GE

NE

_8tra

nspo

sase

(318

-4, 2

-8)

538.

787

871.

70.

562

2Le

ptoI

I_sc

aff_

2_G

EN

E_8

0ce

ram

ide

gluc

osyl

trans

fera

se46

6.3

5137

9.2

3.06

22

Lept

oII_

scaf

f_2_

GE

NE

_81

Fe-S

oxi

dore

duct

ase

567

151

4353

.415

.726

.46

12.2

62

2Le

ptoI

I_sc

aff_

2_G

EN

E_8

2pe

nici

llin

tole

ranc

e pr

otei

n, L

ytB

335

5555

38.1

10.6

15.7

64.

8614

.22

2Le

ptoI

I_sc

aff_

2_G

EN

E_8

3di

hydr

ofla

vono

l 4-r

educ

tase

379

8969

23.6

9.4

2Le

ptoI

I_sc

aff_

2_G

EN

E_8

4un

ique

hyp

othe

tical

269.

710

.84.

732

2Le

ptoI

I_sc

aff_

2_G

EN

E_8

5co

nser

ved

hypo

thet

ical

485

4129

.920

.63.

42

2Le

ptoI

I_sc

aff_

2_G

EN

E_8

6un

ique

hyp

othe

tical

299

416

.86.

364.

963.

85.

72

Lept

oII_

scaf

f_2_

GE

NE

_87

squa

lene

-hop

ene

cycl

ase

785.

70

05.

72.

732

2Le

ptoI

I_sc

aff_

2_G

EN

E_8

9un

ique

hyp

othe

tical

(717

-3, 2

-89)

229

42.7

24.6

16.5

627

.43

2932

.72

2Le

ptoI

I_sc

aff_

2_G

EN

E_9

cons

erve

d hy

poth

etic

al (F

e-S

pro

tein

)9

611

66.2

36.6

656

.232

.93

31.2

22

Lept

oII_

scaf

f_2_

GE

NE

_91

uniq

ue h

ypot

hetic

al (l

ike

cell

divi

sion

initi

atio

n pr

otei

n)20

57

746

.333

.33

4.56

19.6

32

Lept

oII_

scaf

f_2_

GE

NE

_92

cons

erve

d hy

poth

etic

al8

8.4

1220

.86.

932

2Le

ptoI

I_sc

aff_

2_G

EN

E_9

3py

rrol

ine-

5-ca

rbox

ylat

e re

duct

ase

316

3736

35.1

14.5

613

.66

22

Lept

oII_

scaf

f_2_

GE

NE

_96

tubu

lin/F

tsZ

425

8585

44.4

7.86

15.8

20.7

615

.12

2Le

ptoI

I_sc

aff_

2_G

EN

E_9

7ce

ll di

visi

on p

rote

in, F

tsA

465.

660

6043

.19.

0324

.06

17.2

68.

22

2Le

ptoI

I_sc

aff_

2_G

EN

E_9

9D

-ala

D-a

la li

gase

325

6060

53.1

12.9

634

.53

41.9

344

.92

Lept

oII_

scaf

f_20

6_G

EN

E_2

sens

ory

box/

GG

DE

F fa

mily

pro

tein

116

5.9

5147

3.4

1.13

22

Lept

oII_

scaf

f_20

6_G

EN

E_4

alco

hol d

ehyd

roge

nase

388

117

117

66.9

41.8

38.2

352

.06

56.2

22

Lept

oII_

scaf

f_20

6_G

EN

E_5

glyc

osid

ase

575

5951

10.5

7.03

7.73

32

2Le

ptoI

I_sc

aff_

206_

GE

NE

_6gl

ycos

idas

e76

617

414

227

.322

.86

24.2

614

.517

.32

Lept

oII_

scaf

f_21

_GE

NE

_10

uniq

ue h

ypot

hetic

al (s

imila

r to

DN

A p

olym

eras

e III

, del

ta s

ubu n

399.

68

56.

64.

42

2Le

ptoI

I_sc

aff_

21_G

EN

E_1

1un

ique

hyp

othe

tical

(lik

e rib

osom

al p

rote

in S

20)

1011

586

.256

.365

.16

42.9

57.5

2Le

ptoI

I_sc

aff_

21_G

EN

E_1

3re

stric

tion

endo

nucl

ease

/HN

H e

ndon

ucle

ase

229.

632

2612

.94.

32

2Le

ptoI

I_sc

aff_

21_G

EN

E_1

4co

nser

ved

hypo

thet

ical

(sim

ilar t

o fe

rroc

hela

tase

, Hem

H)

386

185

69.2

37.1

637

.54.

3334

.96

35.7

2Le

ptoI

I_sc

aff_

21_G

EN

E_1

7co

nser

ved

hypo

thet

ical

375.

974

31.6

2.93

9.23

2Le

ptoI

I_sc

aff_

21_G

EN

E_1

8un

ique

hyp

othe

tical

375.

99.

63.

22

Lept

oII_

scaf

f_21

_GE

NE

_19

resp

onse

regu

lato

r (H

D-G

YP

dom

ain

prot

ein)

486.

133

126.

82.

262

2Le

ptoI

I_sc

aff_

21_G

EN

E_2

0un

ique

hyp

othe

tical

119

6056

.252

.43.

853

.03

24.8

2Le

ptoI

I_sc

aff_

21_G

EN

E_2

2D

-ala

nine

am

inot

rans

fera

se

3310

2222

9.8

3.26

22

Lept

oII_

scaf

f_21

_GE

NE

_23

rubr

eryt

hrin

: non

hem

e Fe

-bin

ding

pro

tein

/radi

cal d

efen

se/re

duc

155.

345

4592

.177

.93

73.4

56.1

81.5

392

.12

2Le

ptoI

I_sc

aff_

21_G

EN

E_2

4rib

onuc

leot

ide-

diph

osph

ate

redu

ctas

e81

60

077

.240

.43

66.2

38.1

619

22

Lept

oII_

scaf

f_21

_GE

NE

_25

cons

erve

d hy

poth

etic

al54

7.8

1755

.637

.33

28.1

2.63

238.

32

2Le

ptoI

I_sc

aff_

21_G

EN

E_2

6co

nser

ved

hypo

thet

ical

2310

2673

.768

.93

64.0

649

.950

.434

.62

Lept

oII_

scaf

f_21

_GE

NE

_31

uniq

ue h

ypot

hetic

al21

7.9

10.5

3.5

10.5

2Le

ptoI

I_sc

aff_

21_G

EN

E_3

4L-

2,4-

diam

inob

utyr

ic a

cid

acet

yltra

nsfe

rase

217.

940

3323

.52.

6616

.56

2Le

ptoI

I_sc

aff_

21_G

EN

E_3

5di

amin

obut

yrat

e--p

yruv

ate

amin

otra

nsfe

rase

47

7.3

159

140

14.8

2.6

2.36

2Le

ptoI

I_sc

aff_

21_G

EN

E_3

6ec

toin

e sy

ntha

se15

5.3

4845

22.1

7.36

2Le

ptoI

I_sc

aff_

21_G

EN

E_3

7L-

prol

ine

4-hy

drox

ylas

e35

6.4

9028

3815

.06

15.1

67.

532

2Le

ptoI

I_sc

aff_

21_G

EN

E_3

8un

ique

hyp

othe

tical

169

549

492

Lept

oII_

scaf

f_21

_GE

NE

_45

20S

pro

teas

ome

alph

a-su

buni

t 26

555

5535

.416

.56

21.1

22

Lept

oII_

scaf

f_21

_GE

NE

_46

20S

pro

teos

ome,

bet

a su

buni

t29

657

5761

.521

.116

.435

.738

.92

2Le

ptoI

I_sc

aff_

21_G

EN

E_4

7un

ique

hyp

othe

tical

84

45.7

14.3

4042

.86

45.7

22

Lept

oII_

scaf

f_21

_GE

NE

_48

cons

erve

d hy

poth

etic

al56

695

50.3

16.2

317

.99.

92

2Le

ptoI

I_sc

aff_

21_G

EN

E_4

920

S p

rote

asom

e63

657

5756

.925

30.4

15.5

314

.52

2Le

ptoI

I_sc

aff_

21_G

EN

E_5

1ba

cter

iofe

rriti

n 18

840

4086

.142

.443

.63

68.5

686

.12

2Le

ptoI

I_sc

aff_

21_G

EN

E_5

2m

embr

ane

prot

ease

3310

3636

75.5

65.6

47.1

16.1

47.1

21.3

22

Lept

oII_

scaf

f_21

_GE

NE

_53

uniq

ue h

ypot

hetic

al22

974

.864

49.5

313

.03

43.4

319

.82

2Le

ptoI

I_sc

aff_

21_G

EN

E_5

4un

ique

hyp

othe

tical

94.

462

.353

.63

62.3

51.9

22

Lept

oII_

scaf

f_21

_GE

NE

_56

uniq

ue h

ypot

hetic

al12

1031

.312

.73

10.4

18.5

310

.42

2Le

ptoI

I_sc

aff_

21_G

EN

E_5

7Zn

-dep

enda

nt a

lcoh

ol d

ehyd

roge

nase

367

8584

41.3

2.5

17.4

613

.92

Lept

oII_

scaf

f_21

_GE

NE

_58

cons

erve

d hy

poth

etic

al (s

imila

r to

rhod

anes

e-re

late

d su

lfurtr

an8

1011

519

.412

.93

22

Lept

oII_

scaf

f_21

_GE

NE

_59

catio

n ef

flux

pum

p (2

1-59

, 32-

54)

119

100

034

.911

.56

14.8

37.

79.

82

2Le

ptoI

I_sc

aff_

21_G

EN

E_6

0ef

flux

trans

porte

r (32

-53,

21-

60)

3610

2626

7546

.86

52.5

316

.26

39.9

27.1

22

Lept

oII_

scaf

f_21

_GE

NE

_8le

ucyl

-tRN

A s

ynth

etas

e94

60

040

.911

.33

19.6

36.

732

2Le

ptoI

I_sc

aff_

21_G

EN

E_9

uniq

ue h

ypot

hetic

al22

65

11.8

11.8

11.8

2Le

ptoI

I_sc

aff_

213_

GE

NE

_5se

nsor

y bo

x/G

GD

EF

fam

ily p

rote

in

435

3732

134.

332

Lept

oII_

scaf

f_21

3_G

EN

E_7

treha

lose

syn

thas

e65

6.3

00

16.6

5.53

22

Lept

oII_

scaf

f_21

3_G

EN

E_8

treha

lose

syn

thas

e64

6.1

8684

22.7

5.83

9.66

2Le

ptoI

I_sc

aff_

219_

GE

NE

_13

uniq

ue h

ypot

hetic

al19

1016

5.33

2Le

ptoI

I_sc

aff_

219_

GE

NE

_18

mob

iliza

tion

prot

ein

TraI

93

6.8

9159

4.8

1.6

2Le

ptoI

I_sc

aff_

219_

GE

NE

_3co

nser

ved

hypo

thet

ical

(104

2-4,

219

-3)

119.

811

24.7

8.23

22

Lept

oII_

scaf

f_21

9_G

EN

E_5

shuf

flon-

spec

ific

reco

mbi

nase

(104

2-6,

219

-5)

9.9

9.2

2415

237.

662

Lept

oII_

scaf

f_21

9_G

EN

E_6

uniq

ue h

ypot

hetic

al23

116

19.1

12.7

32

2Le

ptoI

I_sc

aff_

22_G

EN

E_1

0ph

osph

ate

AB

C tr

ansp

orte

r, A

TP-b

indi

ng d

omai

n28

694

9364

25.6

27.0

618

.93

22

Lept

oII_

scaf

f_22

_GE

NE

_14

phos

phat

e-bi

ndin

g pe

ripla

smic

pro

tein

, AB

C tr

ansp

orte

r41

1042

4261

32.1

633

.654

.333

.66

22.6

22

Lept

oII_

scaf

f_22

_GE

NE

_18

uniq

ue h

ypot

hetic

al59

54

34.2

32.9

329

.83

20.5

331

.73

23.9

22

Lept

oII_

scaf

f_22

_GE

NE

_19

cons

erve

d hy

poth

etic

al12

928

39.4

16.3

323

.46.

7320

.220

.22

Lept

oII_

scaf

f_22

_GE

NE

_2hi

ston

e de

acet

ylas

e37

643

4310

.12.

462.

562

2Le

ptoI

I_sc

aff_

22_G

EN

E_2

0ad

enyl

osuc

cina

te s

ynth

etas

e47

6.7

137

137

71.8

24.5

640

.221

.928

.92

2Le

ptoI

I_sc

aff_

22_G

EN

E_2

1co

nser

ved

hypo

thet

ical

249

1063

.728

.532

.23

7.5

2Le

ptoI

I_sc

aff_

22_G

EN

E_2

2N

AD

H o

xida

se (n

oxc)

/nitr

ored

ucta

se59

596

2322

.65.

0312

.22

Lept

oII_

scaf

f_22

_GE

NE

_23

ubiq

uino

ne b

iosy

nthe

sis

prot

ein

639.

510

710

212

4.03

2Le

ptoI

I_sc

aff_

22_G

EN

E_2

6un

ique

hyp

othe

tical

285.

416

.68.

232

2Le

ptoI

I_sc

aff_

22_G

EN

E_2

8un

ique

hyp

othe

tical

1411

40.8

33.8

626

.430

.66

27.2

22

Lept

oII_

scaf

f_22

_GE

NE

_29

mem

bran

e ca

rbox

ypep

tidas

e83

9.9

7064

34.5

3.2

15.2

39.

766.

92

2Le

ptoI

I_sc

aff_

22_G

EN

E_3

uniq

ue h

ypot

hetic

al17

945

.36

2624

.222

2Le

ptoI

I_sc

aff_

22_G

EN

E_3

0ce

llula

se42

1065

6539

.116

.96

5.2

11.6

615

.93

22

Lept

oII_

scaf

f_22

_GE

NE

_31

cycl

ic d

iGM

P-b

indi

ng p

rote

in/c

ellu

lose

syn

thas

e su

buni

t81

1025

2335

.714

.212

.36

8.43

5.1

22

Lept

oII_

scaf

f_22

_GE

NE

_33

cellu

lose

syn

thas

e, s

ubun

it c:

cle

aves

diG

MP

syn

thas

e ac

tivat

o10

910

4747

60.4

45.0

638

.313

.56

29.6

314

.72

2Le

ptoI

I_sc

aff_

22_G

EN

E_3

5co

nser

ved

hypo

thet

ical

(sim

ilar t

o ni

troge

n re

gula

tory

pro

tein

P16

628

39.7

11.3

35.

916

.32

Lept

oII_

scaf

f_22

_GE

NE

_36

cons

erve

d hy

poth

etic

al13

6.4

135

18.8

1.8

6.13

1.13

22

Lept

oII_

scaf

f_22

_GE

NE

_39

trans

crip

tiona

l reg

ulat

or (N

ifA fa

mily

)61

711

711

335

.56.

6610

.33

7.6

22

Lept

oII_

scaf

f_22

_GE

NE

_4fru

ctos

e bi

spho

spha

tase

376

121

121

67.8

39.8

37.1

46.0

620

.32

Lept

oII_

scaf

f_22

_GE

NE

_41

flage

llar m

otor

sw

itch

prot

ein

FliM

39

676

7638

.54.

2311

.13

2.76

22

Lept

oII_

scaf

f_22

_GE

NE

_42

efflu

x tra

nspo

rter

4210

5555

68.2

13.9

629

.56

11.3

339

.817

.92

2Le

ptoI

I_sc

aff_

22_G

EN

E_4

4A

BC

tran

spor

ter,

ATP

-bin

ding

pro

tein

269

5252

47.9

14.6

627

.535

.92

2Le

ptoI

I_sc

aff_

22_G

EN

E_4

5py

roph

osph

atas

e21

545

4567

55.4

661

.33

42.7

6564

.32

Lept

oII_

scaf

f_22

_GE

NE

_46

uniq

ue h

ypot

hetic

al23

625

.714

.03

11.2

22

Lept

oII_

scaf

f_22

_GE

NE

_48

uniq

ue h

ypot

hetic

al15

658

.332

.63

38.4

22

Lept

oII_

scaf

f_22

_GE

NE

_6al

dehy

de d

ehyd

roge

nase

556

8686

56.6

26.6

330

.73

13.4

62

Lept

oII_

scaf

f_22

_GE

NE

_7un

ique

hyp

othe

tical

479.

738

.715

.16

8.66

3.43

2Le

ptoI

I_sc

aff_

22_G

EN

E_8

thym

idyl

ate

synt

hase

326.

386

2635

.33.

668.

224

.26

24.6

22

Lept

oII_

scaf

f_22

_GE

NE

_9ph

osph

ate

upta

ke p

rote

in22

540

4071

.943

.23

39.5

310

.23

61.5

58.8

22

Lept

oII_

scaf

f_22

2_G

EN

E_1

uniq

ue h

ypot

hetic

al13

1043

.842

.942

.932

.43

43.5

15.2

22

Lept

oII_

scaf

f_22

2_G

EN

E_3

S-a

deno

sylm

ethi

onin

e ca

rbox

ylas

e17

632

2641

.12.

4324

.341

.12

2Le

ptoI

I_sc

aff_

222_

GE

NE

_4sp

erm

idin

e sy

ntha

se30

5.5

6261

55.8

21.1

614

13.4

20.1

22

Lept

oII_

scaf

f_22

2_G

EN

E_5

argi

nine

/lysi

ne d

ecar

boxy

lase

546.

311

311

311

.51.

98.

62

Lept

oII_

scaf

f_22

2_G

EN

E_6

cons

erve

d hy

poth

etic

al10

59.

416

92.

20.

732

Lept

oII_

scaf

f_22

2_G

EN

E_7

DN

A re

pair

prot

ein

Rec

N63

5.2

6666

24.8

2.46

6.93

7.53

22

Lept

oII_

scaf

f_22

2_G

EN

E_9

thio

redo

xin

125

2929

100

51.5

356

.96

86.4

90.9

386

.42

2Le

ptoI

I_sc

aff_

224_

GE

NE

_1co

nser

ved

hypo

thet

ical

148

1754

5.83

30.1

616

.93

39.1

641

.32

Lept

oII_

scaf

f_22

4_G

EN

E_1

0rib

osom

al la

rge

subu

nit p

seud

ourid

ine

synt

hase

B30

1023

2210

.23.

42

2Le

ptoI

I_sc

aff_

224_

GE

NE

_11

heat

sho

ck p

rote

in (2

24-1

1, 2

88-9

)13

520

2045

.67.

342

.96

44.7

22

Lept

oII_

scaf

f_22

4_G

EN

E_1

2A

BC

tran

spor

ter,

ATP

-bin

ding

pro

tein

(224

-12,

288

-8)

1211

1817

76.2

22.7

49.1

62

Lept

oII_

scaf

f_22

4_G

EN

E_3

DN

A p

rimas

e (9

36-2

, 936

-3, 2

24-3

)46

6.7

3838

29.2

2.53

4.9

2.3

22

Lept

oII_

scaf

f_22

4_G

EN

E_4

RN

A p

olym

eras

e si

gma

fact

or, r

poD

(936

-1, 2

24-4

)68

513

513

557

27.1

630

.47.

4616

.1

22

Lept

oII_

scaf

f_22

4_G

EN

E_5

cons

erve

d hy

poth

etic

al (z

inc

ribbo

n pr

otei

n)30

613

67.6

24.8

342

11.1

656

51.9

22

Lept

oII_

scaf

f_22

4_G

EN

E_6

Rna

se H

157

2525

76.1

70.8

637

.83

30.6

2Le

ptoI

I_sc

aff_

224_

GE

NE

_7nu

cleo

tidyl

trans

fera

se/p

hosp

hohy

drol

ase

576.

394

3012

.75.

862

2Le

ptoI

I_sc

aff_

224_

GE

NE

_8un

ique

hyp

othe

tical

1210

17.3

4.53

13.0

33.

932

Lept

oII_

scaf

f_22

4_G

EN

E_9

uniq

ue h

ypot

hetic

al (s

imila

r to

trans

glyc

osyl

ases

)23

1051

924

.27.

910

.96

2Le

ptoI

I_sc

aff_

23_G

EN

E_1

1un

ique

hyp

othe

tical

158.

942

.16.

57.

266.

762

2Le

ptoI

I_sc

aff_

23_G

EN

E_1

2un

ique

hyp

othe

tical

198

419

.26.

42

Lept

oII_

scaf

f_23

_GE

NE

_13

DN

A li

gase

615.

992

9213

.38.

062

2Le

ptoI

I_sc

aff_

23_G

EN

E_1

5un

ique

hyp

othe

tical

1910

40.2

13.2

330

.16

13.0

32

2Le

ptoI

I_sc

aff_

23_G

EN

E_1

7pe

ptid

e ch

ain

rele

ase

fact

or42

696

9654

.112

.615

.424

.06

232

2Le

ptoI

I_sc

aff_

23_G

EN

E_1

8he

at s

hock

pro

tein

176

1515

63.9

6.56

4.06

34.2

613

.62

2Le

ptoI

I_sc

aff_

23_G

EN

E_1

9A

TP-d

epen

dent

pro

teas

e La

91

60

040

.59.

921

.73

7.36

2Le

ptoI

I_sc

aff_

23_G

EN

E_2

4gl

ucoa

myl

ase

775.

411

511

25

1.66

22

Lept

oII_

scaf

f_23

_GE

NE

_25

hist

idyl

tRN

A s

ynth

etas

e48

7.7

9797

29.1

8.93

10.9

62

Lept

oII_

scaf

f_23

_GE

NE

_27

gluc

oam

ylas

e 74

5.8

122

122

7.6

3.5

2.06

22

Lept

oII_

scaf

f_23

_GE

NE

_28

GTP

-bin

ding

pro

tein

, Lep

A68

5.4

00

18.4

4.86

4.93

5.96

2Le

ptoI

I_sc

aff_

23_G

EN

E_2

9si

gnal

pep

tidas

e I

269.

653

5230

.518

.79.

2614

.33

22

Lept

oII_

scaf

f_23

_GE

NE

_3gl

utam

ine

synt

heta

se54

60

070

54.2

57.7

344

.937

22

Lept

oII_

scaf

f_23

_GE

NE

_30

AD

P-h

epto

se s

ynth

ase

376

6767

48.3

18.4

623

.56

19.6

22.4

22

Lept

oII_

scaf

f_23

_GE

NE

_31

3-de

oxy-

D-m

anno

-oct

ulos

onat

e cy

tidyl

yltra

nsfe

rase

31

547

4724

.97.

9310

.33

11.3

311

.92

2Le

ptoI

I_sc

aff_

23_G

EN

E_3

2C

TP s

ynth

etas

e 61

80

042

.615

.53

26.3

610

.13

22

Lept

oII_

scaf

f_23

_GE

NE

_34

suga

r iso

mer

ase

356

7773

34.3

4.5

25.5

20.5

7.5

2Le

ptoI

I_sc

aff_

23_G

EN

E_3

53-

Deo

xy-D

-man

no-o

ctul

oson

ate

8-ph

osph

ate

phos

phat

ase

206.

728

2545

.66.

419

.23

22.7

32

Lept

oII_

scaf

f_23

_GE

NE

_39

cell

wal

l end

opep

tidas

e33

837

3738

.813

.78.

3612

.616

.12

2Le

ptoI

I_sc

aff_

23_G

EN

E_4

aspa

ryl t

RN

A s

ynth

etas

e66

60

042

.815

.23

27.9

611

.62

2Le

ptoI

I_sc

aff_

23_G

EN

E_4

0tw

o-co

mpo

nent

sen

sor h

istid

ine

kina

se59

6.3

4140

30.7

10.3

319

.86.

832

2Le

ptoI

I_sc

aff_

23_G

EN

E_4

1un

ique

hyp

othe

tical

199

49.1

37.1

45.9

419

.36

2Le

ptoI

I_sc

aff_

23_G

EN

E_4

2ni

troge

n as

sim

ilatio

n re

spon

se re

gula

tor

516

8078

21.4

3.2

72

Lept

oII_

scaf

f_23

_GE

NE

_46

uniq

ue h

ypot

hetic

al11

5.3

9.3

6.2

6.2

2Le

ptoI

I_sc

aff_

23_G

EN

E_5

0un

ique

hyp

othe

tical

(oxi

dore

duct

ase-

like)

295.

99

16.7

5.56

2Le

ptoI

I_sc

aff_

23_G

EN

E_5

1co

nser

ved

hypo

thet

ical

447.

210

9.5

4.36

2Le

ptoI

I_sc

aff_

23_G

EN

E_5

3cy

toch

rom

e C

oxi

dase

hem

e b

and

copp

er-b

indi

ng s

ubun

it (2

333

950

503.

43.

42

Lept

oII_

scaf

f_23

_GE

NE

_6G

MP

syn

thas

e (2

3-6,

703

-2)

576.

515

815

816

.510

.73

4.36

22

Lept

oII_

scaf

f_23

_GE

NE

_7in

osin

e m

onop

hosp

hate

deh

ydro

gena

se (7

03-1

, 23-

7)53

8.9

171

171

60.5

26.4

344

.627

.33

26.8

22

Lept

oII_

scaf

f_23

_GE

NE

_9A

TPas

e w

ith c

hape

rone

act

ivity

, ATP

-bin

ding

dom

ain

346

2221

3417

.43

18.2

32

Lept

oII_

scaf

f_23

2_G

EN

E_1

3un

ique

hyp

othe

tical

(232

-13,

829

-1)

258.

913

4.33

2Le

ptoI

I_sc

aff_

232_

GE

NE

_4A

BC

tran

spor

t pro

tein

, ATP

-bin

ding

sub

unit/

Rec

F43

5.9

1918

12.1

4.03

4.03

2Le

ptoI

I_sc

aff_

232_

GE

NE

_9co

nser

ved

hypo

thet

ical

(pha

ge-r

elat

ed)

1111

2232

.710

.92

2Le

ptoI

I_sc

aff_

234_

GE

NE

_5ac

etol

acta

te s

ynth

ase,

larg

e su

buni

t, bi

osyn

thet

ic ty

pe64

60

012

.44.

535.

763.

42

Lept

oII_

scaf

f_25

_GE

NE

_12

iron-

sulfu

r clu

ster

-bin

ding

pro

tein

509.

623

235.

41.

82

Lept

oII_

scaf

f_25

_GE

NE

_16

AD

P-r

ibos

e py

roph

osph

atas

e21

5.1

2320

6.6

2.2

22

Lept

oII_

scaf

f_25

_GE

NE

_18

sens

ory

box

prot

ein/

sigm

a-54

dep

ende

nt D

NA

-bin

ding

resp

ons

538

9595

37.2

6.06

10.9

33.

232

2Le

ptoI

I_sc

aff_

25_G

EN

E_1

9an

thra

nila

te s

ynth

ase

com

pone

nt I

575.

810

910

630

.73.

4618

.86

22

Lept

oII_

scaf

f_25

_GE

NE

_2cy

toch

rom

e c

oxid

ase,

fixO

sub

unit

(25-

2, 1

20-1

4)20

8.8

1818

71.6

59.6

666

.518

65.3

666

.52

Lept

oII_

scaf

f_25

_GE

NE

_20

anth

rani

late

syn

thas

e, c

ompo

nent

II22

5.5

6363

41.

332

2Le

ptoI

I_sc

aff_

25_G

EN

E_2

1an

thra

nila

te p

hosp

horib

osyl

trans

fera

se36

5.8

6969

15.7

5.23

22

Lept

oII_

scaf

f_25

_GE

NE

_24

trypt

opha

n sy

ntha

se, b

eta

subu

nit (

132-

2, 2

5-24

)45

914

214

243

.916

.73

20.3

32.

8314

.32

2Le

ptoI

I_sc

aff_

25_G

EN

E_2

5try

ptop

han

synt

hase

alp

ha c

hain

29

744

4426

.18.

210

.73

13.2

32

Lept

oII_

scaf

f_25

_GE

NE

_26

acet

yl-C

oA c

arbo

xyla

se, c

arbo

xyl t

rans

fera

se, b

eta

subu

nit

338.

685

8527

7.43

13.8

2.96

2Le

ptoI

I_sc

aff_

25_G

EN

E_2

7fo

lylp

olyg

luta

mat

e sy

ntha

se49

5.5

4646

12.6

2.33

3.3

2Le

ptoI

I_sc

aff_

25_G

EN

E_2

8or

gani

c so

lven

t tol

eran

ce p

rote

in

844.

719

1316

.59.

562.

931.

12

2Le

ptoI

I_sc

aff_

25_G

EN

E_2

9co

nser

ved

hypo

thet

ical

309

1028

.94.

634.

8614

.425

.62

Lept

oII_

scaf

f_25

_GE

NE

_3un

ique

hyp

othe

tical

126

7.3

2.43

2Le

ptoI

I_sc

aff_

25_G

EN

E_3

0A

TP-N

AD

kin

ase

346.

161

6113

.85.

92

2Le

ptoI

I_sc

aff_

25_G

EN

E_3

1gl

utam

ate

synt

hase

675

102

102

76.7

62.4

658

5425

.92

2Le

ptoI

I_sc

aff_

25_G

EN

E_3

2cy

toch

rom

e b6

com

plex

Rie

ske

Fe-S

pro

tein

2310

1414

75.2

45.7

641

.64.

5348

.03

652

Lept

oII_

scaf

f_25

_GE

NE

_34

cons

erve

d hy

poth

etic

al (s

imila

r to

men

aqui

nol-c

ytoc

hrom

e-c

re30

8.5

245

6.2

2.06

22

Lept

oII_

scaf

f_25

_GE

NE

_36

cons

erve

d hy

poth

etic

al

369

2838

.616

.73

8.5

22.1

37.

22

Lept

oII_

scaf

f_25

_GE

NE

_37

AB

C tr

ansp

orte

r, A

TP-b

indi

ng p

rote

in37

6.8

7067

23.2

2.86

10.6

22

Lept

oII_

scaf

f_25

_GE

NE

_39

cons

erve

d hy

poth

etic

al18

933

3921

.76

20.9

64.

6626

.63

18.3

22

Lept

oII_

scaf

f_25

_GE

NE

_40

sign

al p

eptid

e pe

ptid

ase

3610

5454

4534

.626

.96

7.06

20.0

319

.32

2Le

ptoI

I_sc

aff_

25_G

EN

E_4

1un

ique

hyp

othe

tical

1410

4239

.222

.42

Lept

oII_

scaf

f_25

_GE

NE

_44

ATP

syn

thas

e be

ta s

ubun

it/tra

nsrip

tion

term

inat

ion

fact

or rh

o41

5.2

3823

9.5

3.16

22

Lept

oII_

scaf

f_25

_GE

NE

_46

uniq

ue h

ypot

hetic

al24

1035

.928

.06

22.9

12.7

22.5

617

.72

Lept

oII_

scaf

f_25

_GE

NE

_47

uniq

ue h

ypot

hetic

al17

9.8

1714

.73

4.76

2Le

ptoI

I_sc

aff_

25_G

EN

E_5

uniq

ue h

ypot

hetic

al (s

omew

hat l

ike

cyt c

)14

6.8

40.3

9.4

19.4

22

Lept

oII_

scaf

f_25

_GE

NE

_50

inos

ine-

5'-m

onop

hosp

hate

deh

ydro

gena

se17

523

1353

.932

.46

41.4

348

.66

51.3

22

Lept

oII_

scaf

f_25

_GE

NE

_53

uniq

ue h

ypot

hetic

al26

845

10.4

7.5

30.3

317

.86

22

Lept

oII_

scaf

f_25

_GE

NE

_54

urac

il ph

osph

orib

osyl

trans

fera

se

226

4545

37.7

514

.43

35.5

324

.62

Lept

oII_

scaf

f_25

_GE

NE

_55

aspa

rtate

car

bam

oyltr

ansf

eras

e34

9.1

8585

43.8

3.8

88.

962

Lept

oII_

scaf

f_25

_GE

NE

_56

dihy

droo

rota

se48

5.9

113

109

24.7

5.1

8.6

22

Lept

oII_

scaf

f_25

_GE

NE

_57

carb

amoy

l-pho

spha

te s

ynth

ase

smal

l cha

in40

6.5

8684

18.1

5.93

4.2

2Le

ptoI

I_sc

aff_

25_G

EN

E_5

8py

ruva

te fo

rmat

e-ly

ase

1 ac

tivat

ing

enzy

me

375.

479

706

22

2Le

ptoI

I_sc

aff_

25_G

EN

E_5

9ca

rbam

oyl p

hosp

hate

syn

thet

ase

larg

e su

buni

t11

85

00

34.4

13.2

318

.86

0.63

5.76

5.8

2Le

ptoI

I_sc

aff_

25_G

EN

E_6

un

ique

hyp

othe

tical

85.

119

.16.

42

2Le

ptoI

I_sc

aff_

25_G

EN

E_6

0tra

nscr

iptio

n el

onga

tion

fact

or (1

108-

1, 2

5-60

)18

5.8

3636

81.2

46.2

324

.819

.16

56.0

349

.42

Lept

oII_

scaf

f_25

_GE

NE

_7un

ique

hyp

othe

tical

1710

20.6

6.86

22

Lept

oII_

scaf

f_25

_GE

NE

_9se

rine/

thre

onin

e ki

nase

40

928

2739

.224

.56

15.3

2.2

5.73

22

Lept

oII_

scaf

f_26

_GE

NE

_10

trans

posa

se (2

-125

, 26-

10, 2

-128

)51

1047

4725

.38.

566.

432

Lept

oII_

scaf

f_26

_GE

NE

_15

aden

ine

spec

ific

DN

A m

ethy

ltran

sfer

ase/

helic

ase

127.

40

018

.22

5.43

2Le

ptoI

I_sc

aff_

26_G

EN

E_2

4(2

6-24

, 132

-2) s

srA

-bin

ding

pro

tein

1910

3535

47.2

5.93

14.5

332

.32

2Le

ptoI

I_sc

aff_

26_G

EN

E_2

5le

ucyl

am

inop

eptid

ase

(sim

ilar t

o 18

3-9,

132

-1)

509

9393

6541

.96

47.5

39.

5642

.86

402

2Le

ptoI

I_sc

aff_

26_G

EN

E_2

6E

xsb

prot

ein:

suc

cino

glyc

an s

ynth

esis

/tran

scrip

tion/

ATP

ase

(si

276

6363

54.4

16.0

324

.76

23.5

25.3

2Le

ptoI

I_sc

aff_

26_G

EN

E_2

7ra

dica

l act

ivat

ing

enzy

me

(183

-7, 2

6-27

)18

4.5

2625

196.

332

2Le

ptoI

I_sc

aff_

26_G

EN

E_2

8un

ique

hyp

othe

tical

(183

-6, 2

6-28

)30

95

70.8

50.9

350

.43

1442

.06

42.4

22

Lept

oII_

scaf

f_26

_GE

NE

_29

DN

A g

yras

e (s

imila

r to

183-

5)90

60

036

.318

.23

22.4

7.33

5.8

2Le

ptoI

I_sc

aff_

26_G

EN

E_3

CR

ISP

R-a

ssoc

iate

d pr

otei

n C

as1

349

130

130

7.8

2.6

22

Lept

oII_

scaf

f_26

_GE

NE

_30

DN

A g

yras

e, B

sub

unit

(sim

ilar t

o 18

3-4)

926

00

40.8

12.2

322

.56

5.13

12.8

22

Lept

oII_

scaf

f_26

_GE

NE

_31

DN

A p

olym

eras

e III

(sim

ilar t

o 18

3-3)

435

2826

72.1

38.7

649

.03

36.5

331

22

Lept

oII_

scaf

f_26

_GE

NE

_32

chro

mos

omal

repl

icat

ion

initi

ator

pro

tein

Dna

A (s

imila

r to

183-

253

8.6

101

9936

.14.

3619

.23

5.3

22

Lept

oII_

scaf

f_26

_GE

NE

_33

acet

olac

tate

syn

thas

e (1

83-1

, 26-

33)

646

00

46.3

20.9

320

.815

.39.

82

2Le

ptoI

I_sc

aff_

26_G

EN

E_3

4ac

etol

acta

te s

ynth

ase

216

4242

58.7

12.3

13.4

336

.76

15.8

22

Lept

oII_

scaf

f_26

_GE

NE

_35

keto

-aci

d re

duct

oiso

mer

ase

376

134

134

41.6

23.7

21.1

621

.13

17.4

2Le

ptoI

I_sc

aff_

26_G

EN

E_3

6ph

osph

atid

ylse

rine

deca

rbox

ylas

e pr

oenz

yme

249.

345

4522

.13.

239.

82

2Le

ptoI

I_sc

aff_

26_G

EN

E_3

82-

isop

ropy

lmal

ate

synt

hase

585.

915

015

034

.83.

514

.43

8.63

22

Lept

oII_

scaf

f_26

_GE

NE

_39

isoc

itrat

e de

hydr

ogen

ase

406

109

109

48.9

26.0

332

.96

33.0

624

.32

2Le

ptoI

I_sc

aff_

26_G

EN

E_4

cons

erve

d hy

poth

etic

al18

1017

39.3

18.2

23.1

327

.62

2Le

ptoI

I_sc

aff_

26_G

EN

E_4

0as

parta

te s

emia

ldeh

yde

dehy

drog

enas

e36

610

098

66.5

40.6

345

.642

.83

51.3

22

Lept

oII_

scaf

f_26

_GE

NE

_41

quin

olin

ate

synt

heta

se c

ompl

ex35

580

8034

.83.

614

.76

16.3

615

.22

2Le

ptoI

I_sc

aff_

26_G

EN

E_4

4fe

rrid

oxin

oxi

dore

duct

ase

219

5252

72.5

49.7

355

.664

.93

63.2

2Le

ptoI

I_sc

aff_

26_G

EN

E_4

6un

ique

hyp

othe

tical

399.

66.

62.

21.

232

2Le

ptoI

I_sc

aff_

26_G

EN

E_5

cons

erve

d hy

poth

etic

al26

947

60.4

10.4

332

.16

36.2

617

.62

2Le

ptoI

I_sc

aff_

26_G

EN

E_6

cons

erve

d hy

poth

etic

al44

686

90.7

58.9

669

.03

3.16

64.7

363

.32

2Le

ptoI

I_sc

aff_

26_G

EN

E_7

cons

erve

d hy

poth

etic

al20

618

82.5

37.2

348

.33

43.6

349

.72

2Le

ptoI

I_sc

aff_

26_G

EN

E_8

cons

erve

d hy

poth

etic

al58

647

62.4

13.4

637

.617

.76

14.2

2Le

ptoI

I_sc

aff_

26_G

EN

E_9

CR

ISP

R-a

ssoc

iate

d he

licas

e C

as3

100

5.8

135

6523

.13.

538.

72.

462

Lept

oII_

scaf

f_26

1_G

EN

E_1

trans

posa

se (

261-

1, 2

61-8

, 173

-15,

265

-11,

412

-1)

1710

3430

12.2

4.06

2Le

ptoI

I_sc

aff_

261_

GE

NE

_3m

rr re

stric

tion

syst

em p

rote

in34

6.2

9292

24.2

2.76

8.36

5.83

2Le

ptoI

I_sc

aff_

261_

GE

NE

_8tra

nspo

sase

(261

-1, 1

73-1

5, 2

61-8

, 265

-11,

412

-1)

499.

713

812

710

.93.

631.

462

2Le

ptoI

I_sc

aff_

261_

GE

NE

_9tra

nspo

sase

-like

(73-

38, 1

73-1

6, 4

12-2

, 265

-10,

261

-9)

255.

438

3871

.434

.13

30.2

54.4

337

.12

Lept

oII_

scaf

f_26

5_G

EN

E_1

germ

line

RN

A h

elic

ase

299.

812

1236

.47

19.3

22

Lept

oII_

scaf

f_26

5_G

EN

E_1

0tra

nspo

sase

-like

(73-

38, 1

73-1

6, 4

12-2

, 265

-10,

261

-9)

255.

438

3871

.434

.13

30.2

54.4

337

.12

Lept

oII_

scaf

f_26

5_G

EN

E_1

1tra

nspo

sase

(17

3-15

, 261

-8, 2

65-1

1, 4

12-1

)49

9.7

138

127

10.9

3.63

1.46

22

Lept

oII_

scaf

f_26

5_G

EN

E_1

4un

ique

hyp

othe

tical

1710

775

.260

.33

41.4

732

.922

.92

Lept

oII_

scaf

f_26

5_G

EN

E_9

uniq

ue h

ypot

hetic

al8

5.6

39.5

39.5

22

Lept

oII_

scaf

f_27

_GE

NE

_1ac

yl c

arrie

r pro

tein

(295

-11,

27-

1)27

960

6045

20.7

28.9

632

.93

27.1

2Le

ptoI

I_sc

aff_

27_G

EN

E_1

01-

deox

y-D

-xyl

ulos

e 5-

phos

phat

e re

duct

oiso

mer

ase

426.

293

9316

.86.

72

2Le

ptoI

I_sc

aff_

27_G

EN

E_1

3un

ique

hyp

othe

tical

6810

554

.942

.538

.66

40.2

336

.83

26.2

22

Lept

oII_

scaf

f_27

_GE

NE

_14

form

ate-

-tetra

hydr

ofol

ate

ligas

e 59

813

413

434

.69.

715

.97.

9310

.12

2Le

ptoI

I_sc

aff_

27_G

EN

E_1

8un

ique

hyp

othe

tical

97

35.9

9.4

26.9

335

.9

22

Lept

oII_

scaf

f_27

_GE

NE

_2m

alon

yl-c

oA a

cyl c

arrie

r pro

tein

tran

sacy

lase

346

5656

41.1

22.4

30.2

629

.73

31.2

2Le

ptoI

I_sc

aff_

27_G

EN

E_2

0gl

ycop

rote

in e

ndop

eptid

ase

245

1212

12.1

4.03

2Le

ptoI

I_sc

aff_

27_G

EN

E_2

1D

NA

repa

ir pr

otei

n R

adA

497.

111

111

114

.33.

762.

162

2Le

ptoI

I_sc

aff_

27_G

EN

E_2

2un

ique

hyp

othe

tical

264.

84.

53

32

Lept

oII_

scaf

f_27

_GE

NE

_23

cons

erve

d hy

poth

etic

al (s

imila

r to

lysi

ne d

ecar

boxy

lase

s/nu

cle

246

194

32.7

3.73

4.53

9.66

22

Lept

oII_

scaf

f_27

_GE

NE

_24

Pm

bA p

rote

in, p

rote

ases

/DN

A g

yras

e m

odul

ator

496

8378

4429

.33

22.9

325

.86

19.7

22

Lept

oII_

scaf

f_27

_GE

NE

_25

TldD

pro

tein

, pro

teas

e/D

NA

gyr

ase

mod

ulat

or57

714

614

143

.520

.426

.211

.917

.82

Lept

oII_

scaf

f_27

_GE

NE

_29

phyt

oene

syn

thas

e37

8.7

4326

10.9

3.63

2Le

ptoI

I_sc

aff_

27_G

EN

E_3

3-ox

oacy

l-(ac

yl-c

arrie

r-pr

otei

n) s

ynth

ase

III37

5.4

8989

5.3

4.5

22

Lept

oII_

scaf

f_27

_GE

NE

_30

crea

tinas

e 27

655

5139

11.2

615

.53

17.1

32

Lept

oII_

scaf

f_27

_GE

NE

_31

chro

mos

ome

parti

tion

prot

ein

A23

6.8

4643

61.5

27.4

22.1

32

Lept

oII_

scaf

f_27

_GE

NE

_33

mur

amoy

ltetra

pept

ide

carb

oxyp

eptid

ase

355.

726

2212

.28.

132

2Le

ptoI

I_sc

aff_

27_G

EN

E_3

4un

ique

hyp

othe

tical

546

746.

133.

1370

.56

21.8

314

22

Lept

oII_

scaf

f_27

_GE

NE

_35

uniq

ue h

ypot

hetic

al43

9.8

31.2

7.1

6.73

12.3

623

.92

2Le

ptoI

I_sc

aff_

27_G

EN

E_3

6un

ique

hyp

othe

tical

165.

678

.411

.46

10.8

17.1

57.4

318

.92

Lept

oII_

scaf

f_27

_GE

NE

_38

uniq

ue h

ypot

hetic

al (l

ike

star

vatio

n-in

duci

ble

oute

r mem

bran

e l

219

655

.932

.63

34.5

69.

932

2Le

ptoI

I_sc

aff_

27_G

EN

E_3

9un

ique

hyp

othe

tical

259

73.9

38.2

638

.23

49.7

52.8

22

Lept

oII_

scaf

f_27

_GE

NE

_4fa

tty a

cid/

phos

phol

ipid

syn

thes

is p

rote

in P

lsX

35

8.5

8484

30.8

7.06

20.3

316

.116

.92

2Le

ptoI

I_sc

aff_

27_G

EN

E_4

0ph

age

shoc

k pr

otei

n26

514

1384

.412

.73

9.46

55.2

663

.472

.42

2Le

ptoI

I_sc

aff_

27_G

EN

E_4

1un

ique

hyp

othe

tical

475.

946

.129

.83

27.4

727

.96

22.9

22

Lept

oII_

scaf

f_27

_GE

NE

_42

cons

erve

d hy

poth

etic

al40

9.4

4258

.53.

0614

.93

32.1

318

.72

Lept

oII_

scaf

f_27

_GE

NE

_43

uniq

ue h

ypot

hetic

al22

1050

.37.

642

.33.

632

2Le

ptoI

I_sc

aff_

27_G

EN

E_4

7he

licas

e/m

ethy

ltran

sfer

ase

(27-

47, 1

153-

2)18

66

00

37.1

1115

.33

1.33

1.86

22

Lept

oII_

scaf

f_27

_GE

NE

_5un

ique

hyp

othe

tical

(lik

e rib

osom

al p

rote

in L

32)

711

99

5019

.43

28.3

329

.43

3050

22

Lept

oII_

scaf

f_27

_GE

NE

_51

uniq

ue h

ypot

hetic

al10

591

.711

.512

.365

.06

82.1

2Le

ptoI

I_sc

aff_

27_G

EN

E_5

2un

ique

hyp

othe

tical

175.

218

.56.

162

2Le

ptoI

I_sc

aff_

27_G

EN

E_7

prol

yl-tR

NA

syn

thet

ase

476

100

100

27.3

14.0

318

.713

.92

2Le

ptoI

I_sc

aff_

27_G

EN

E_8

pept

idog

lyca

n ac

ylat

ion

416

117

117

61.8

25.9

642

.36

32.3

621

.82

2Le

ptoI

I_sc

aff_

27_G

EN

E_9

zinc

met

allo

pept

idas

e 39

1078

6118

.611

.611

.32

2Le

ptoI

I_sc

aff_

271_

GE

NE

_1G

TPas

e E

F-Tu

(sim

ilar t

o 13

7-1)

109

3838

71.3

48.2

347

.53

3971

.32

Lept

oII_

scaf

f_27

1_G

EN

E_1

0ra

re li

popr

otei

n A

2910

2827

20.5

8.6

2.53

22

Lept

oII_

scaf

f_27

1_G

EN

E_1

2rib

osom

al p

rote

in S

18 (2

71-1

2, 5

3-1)

910

1616

61.8

23.2

637

.339

.06

43.4

22

Lept

oII_

scaf

f_27

1_G

EN

E_1

3si

ngle

-stra

nd D

NA

bin

ding

pro

tein

(53-

2, 2

71-1

3)16

521

2047

.914

.76

4.3

9.53

45.7

22

Lept

oII_

scaf

f_27

1_G

EN

E_1

4un

ique

hyp

othe

tical

(lik

e rib

osom

al p

rote

in S

6) (2

71-1

4, 5

3-3)

149

88

45.9

33.6

25.1

322

.145

.63

37.7

22

Lept

oII_

scaf

f_27

1_G

EN

E_2

uniq

ue h

ypot

hetic

al28

546

.621

.131

.430

.83

8.7

22

Lept

oII_

scaf

f_27

1_G

EN

E_3

flavo

prot

ein

oxid

ored

ucta

se42

713

113

167

.549

.844

.618

.33

60.6

56.5

2Le

ptoI

I_sc

aff_

271_

GE

NE

_6tR

NA

mod

ifyin

g en

zym

e 54

698

9729

.44

19.1

62.

22

2Le

ptoI

I_sc

aff_

271_

GE

NE

_7un

ique

hyp

othe

tical

179

4333

.128

.03

7.5

33.1

33.8

22

Lept

oII_

scaf

f_27

1_G

EN

E_9

uniq

ue h

ypot

hetic

al9

1035

.111

.26

26.1

17.1

14.9

22

Lept

oII_

scaf

f_27

4_G

EN

E_1

ribos

omal

pro

tein

S1

665

148

148

70.9

44.1

352

.73

1.63

32.5

628

.82

2Le

ptoI

I_sc

aff_

274_

GE

NE

_10

lipop

rote

in

4610

1917

21.4

3.2

10.1

35.

72

2Le

ptoI

I_sc

aff_

274_

GE

NE

_2si

gnal

pep

tidas

e32

1046

4449

.527

35.4

624

.83

21.7

22

Lept

oII_

scaf

f_27

4_G

EN

E_3

sign

al re

cogn

ition

par

ticle

pro

tein

49

910

810

869

.828

.16

38.7

334

.36

29.5

22

Lept

oII_

scaf

f_27

4_G

EN

E_4

ribos

omal

pro

tein

S16

911

1616

55.6

23.8

653

.13

3739

.52

2Le

ptoI

I_sc

aff_

274_

GE

NE

_5co

nser

ved

hypo

thet

ical

(sim

ilar t

o R

NA

bin

ding

pro

tein

)8

812

948

.735

.546

.127

.63

34.2

2Le

ptoI

I_sc

aff_

274_

GE

NE

_6tR

NA

(gua

nine

-N1)

-met

hyltr

ansf

eras

e27

5.5

5454

33.6

19.6

32

2Le

ptoI

I_sc

aff_

274_

GE

NE

_7rib

osom

al p

rote

in L

1913

1026

2674

.652

.53

47.7

359

.353

.42

Lept

oII_

scaf

f_27

7_G

EN

E_1

uniq

ue h

ypot

hetic

al (2

77-1

, 43-

30)

169.

124

.84.

9310

.06

22

Lept

oII_

scaf

f_27

7_G

EN

E_2

actin

-like

ATP

ase

(277

-2, 4

3-31

)37

611

511

560

.443

.748

.36

35.2

33.1

2Le

ptoI

I_sc

aff_

277_

GE

NE

_3ro

d sh

ape-

dete

rmin

ing

prot

ein

Mre

C31

920

207.

52.

52

Lept

oII_

scaf

f_27

7_G

EN

E_5

pept

idog

lyca

n sy

nthe

tase

/Cel

l div

isio

n pr

otei

n Ft

sI70

9.7

121

114

6.2

3.73

22

Lept

oII_

scaf

f_27

7_G

EN

E_7

ribon

ucle

ase

G60

512

712

754

.816

.96

29.2

23.3

624

22

Lept

oII_

scaf

f_28

3_G

EN

E_2

hem

e d1

bio

synt

hesi

s pr

otei

n N

irJ (6

82-5

, 283

-2)

398

141

1417

.515

.16

5.16

22

Lept

oII_

scaf

f_28

3_G

EN

E_3

quin

one

oxid

ored

ucta

se (6

82-6

, 283

-3)

368

8141

22.2

10.4

17.2

14.4

8.4

22

Lept

oII_

scaf

f_28

3_G

EN

E_5

prot

opor

phyr

inog

en o

xida

se

509

6462

21.2

14.0

67.

42

Lept

oII_

scaf

f_28

7_G

EN

E_4

uniq

ue h

ypot

hetic

al23

915

.511

.66

22

Lept

oII_

scaf

f_28

7_G

EN

E_6

uniq

ue h

ypot

hetic

al (s

imila

r to

429-

5)50

5.7

68.

23.

562

2Le

ptoI

I_sc

aff_

287_

GE

NE

_7co

nser

ved

hypo

thet

ical

(glu

tare

doxi

n: m

olyb

do e

nzym

e ca

taly

z15

610

340

25.1

628

.63

17.5

332

.06

28.1

22

Lept

oII_

scaf

f_28

8_G

EN

E_1

helic

ase

(104

5-1,

288

-1)

4910

8682

60.1

13.9

23.8

17.1

639

.42

Lept

oII_

scaf

f_28

8_G

EN

E_2

anth

rani

late

syn

thas

e co

mpo

nent

II27

5.6

2727

30.1

6.96

6.13

2Le

ptoI

I_sc

aff_

288_

GE

NE

_3gl

utam

ate

race

mas

e34

5.6

5050

57.3

17.5

22.9

626

.96

22

Lept

oII_

scaf

f_28

8_G

EN

E_4

beta

-hex

osam

inid

ase

389

5050

70.2

17.1

623

.335

.56

16.4

22

Lept

oII_

scaf

f_28

8_G

EN

E_5

xant

hosi

ne tr

ipho

spha

te p

yrop

hosp

hata

se21

729

2663

.118

.53

37.3

638

.715

.72

2Le

ptoI

I_sc

aff_

288_

GE

NE

_6rib

onuc

leas

e27

677

7753

.116

.73

27.6

333

.647

.23

32.2

22

Lept

oII_

scaf

f_28

8_G

EN

E_7

uniq

ue h

ypot

hetic

al33

5.7

38.9

9.46

17.1

9.86

22

Lept

oII_

scaf

f_28

8_G

EN

E_8

AB

C tr

ansp

orte

r, A

TP-b

indi

ng p

rote

in (2

24-1

2, 2

88-8

)72

612

912

945

.38.

1328

.76

4.2

22

Lept

oII_

scaf

f_28

8_G

EN

E_9

chap

eron

e (2

24-1

1, 2

88-9

)17

5.5

2819

59.9

5.46

54.3

638

.82

2Le

ptoI

I_sc

aff_

294_

GE

NE

_2co

nser

ved

hypo

thet

ical

(dom

ain

foun

d in

pre

dict

ed A

TP-d

epen

745

4154

.619

.86

35.4

15.3

3.3

2Le

ptoI

I_sc

aff_

294_

GE

NE

_3un

ique

hyp

othe

tical

135.

255

.910

.73

25.7

38.

22

Lept

oII_

scaf

f_29

5_G

EN

E_1

gluc

ose

6-ph

osph

ate

dehy

drog

enas

e (s

imila

r to

135-

11)

116.

719

1930

.727

.42

2Le

ptoI

I_sc

aff_

295_

GE

NE

_10

acyl

car

rier p

rote

in9

419

1947

.445

.642

.96

43.8

346

.544

.72

2Le

ptoI

I_sc

aff_

295_

GE

NE

_11

acyl

car

rier p

rote

in (2

95-1

1, 2

7-1)

169

4442

53.7

29.2

339

.23

43.0

628

.62

2Le

ptoI

I_sc

aff_

295_

GE

NE

_26-

phos

phog

luco

nate

deh

ydro

gena

se (1

35-1

2, 2

95-2

)37

5.9

126

116

33.9

23.5

627

.23

27.4

313

.32

2Le

ptoI

I_sc

aff_

295_

GE

NE

_4ph

osph

orib

osyl

glyc

inam

ide

form

yltra

nsfe

rase

23

948

4818

.46.

136.

1313

.210

.62

Lept

oII_

scaf

f_29

5_G

EN

E_5

phos

phor

ibos

ylfo

rmyl

glyc

inam

idin

e cy

clo-

ligas

e 38

5.7

9292

183.

537.

832

Lept

oII_

scaf

f_29

5_G

EN

E_8

ribon

ucle

ase

III28

6.2

4848

23.5

6.2

10.1

22

Lept

oII_

scaf

f_29

5_G

EN

E_9

beta

-ket

oacy

l-acy

l car

rier p

rote

in s

ynth

ase

II42

5.7

134

126

47.4

24.7

21.6

4.56

22.9

22

Lept

oII_

scaf

f_29

7_G

EN

E_2

arse

nate

redu

ctas

e (2

97-2

, 46-

2)24

822

2270

.630

.63

34.5

33.

6332

.13

49.3

22

Lept

oII_

scaf

f_29

7_G

EN

E_4

uniq

ue h

ypot

hetic

al (2

97-4

, 46-

1)20

934

.522

9.53

26.2

31.5

623

.82

2Le

ptoI

I_sc

aff_

297_

GE

NE

_5un

ique

hyp

othe

tical

269

67.5

56.2

653

.83

54.8

47.6

41.6

22

Lept

oII_

scaf

f_29

7_G

EN

E_6

cons

erve

d hy

poth

etic

al (K

elch

-like

pro

tein

)58

1013

46.1

23.0

331

.417

132

Lept

oII_

scaf

f_3_

GE

NE

_1ex

orib

onuc

leas

e II

(333

-10,

3-1

)52

5.8

8879

13.2

2.03

4.76

22

Lept

oII_

scaf

f_3_

GE

NE

_10

UD

P-g

luco

se p

yrop

hosp

hory

lase

326

9595

77.8

53.8

658

.03

3.26

62.0

651

.22

Lept

oII_

scaf

f_3_

GE

NE

_100

sens

ory

box/

GG

DE

F do

mai

n/E

AL

dom

ain

prot

ein

405.

542

3712

.12.

36.

332

2Le

ptoI

I_sc

aff_

3_G

EN

E_1

04ca

rbon

ic a

nhyd

rase

(147

-15,

3-1

04, 5

81-2

)21

8.5

7619

9.3

2.23

7.56

22

Lept

oII_

scaf

f_3_

GE

NE

_11

deph

osph

o-C

oA k

inas

e 23

633

3356

.97.

6635

.43

22.1

2Le

ptoI

I_sc

aff_

3_G

EN

E_1

3un

ique

hyp

othe

tical

259.

89

22.3

5.1

5.23

22

Lept

oII_

scaf

f_3_

GE

NE

_14

DN

A p

olym

eras

e I

986

143

143

28.9

5.86

10.9

65.

434.

72

2Le

ptoI

I_sc

aff_

3_G

EN

E_1

5br

anch

ed-c

hain

am

ino

acid

tran

sfer

ase

356

9894

88.1

57.1

638

.627

.117

.12

2Le

ptoI

I_sc

aff_

3_G

EN

E_1

9tra

nscr

iptio

nal r

egul

ator

349

3834

59.1

19.1

324

.96

15.0

611

.22

Lept

oII_

scaf

f_3_

GE

NE

_20

ATP

-dep

ende

nt D

NA

hel

icas

e82

6.5

135

133

9.1

1.13

6.23

22

Lept

oII_

scaf

f_3_

GE

NE

_22

uniq

ue h

ypot

hetic

al54

67

54.5

13.6

626

.37.

632

Lept

oII_

scaf

f_3_

GE

NE

_23

uniq

ue h

ypot

hetic

al (i

ojap

-rel

ated

pro

tein

) 16

67

34.6

30.1

36.

6327

.92

Lept

oII_

scaf

f_3_

GE

NE

_25

nico

tinam

ide-

nucl

eotid

e ad

enyl

yltra

nsfe

rase

269.

222

2116

.55.

52

2Le

ptoI

I_sc

aff_

3_G

EN

E_2

6ga

mm

a gl

utam

yl p

hosp

hate

redu

ctas

e46

6.2

102

102

56.3

3.56

33.3

613

.23

8.1

22

Lept

oII_

scaf

f_3_

GE

NE

_27

glut

amat

e 5-

kina

se41

1071

7122

.90.

9611

.33

2.9

22

Lept

oII_

scaf

f_3_

GE

NE

_28

Spo

0B-a

ssoc

iate

d G

TP-b

indi

ng p

rote

in

397

7772

61.1

3.43

21.5

614

.26

34.7

22

Lept

oII_

scaf

f_3_

GE

NE

_29

ribos

omal

pro

tein

L27

1011

2424

58.7

13.4

55.4

42.0

350

.73

58.7

22

Lept

oII_

scaf

f_3_

GE

NE

_30

ribos

omal

pro

tein

L21

1211

1414

70.8

41.8

58.5

56.3

50.9

22

Lept

oII_

scaf

f_3_

GE

NE

_31

ferr

ic u

ptak

e re

gula

tor

186.

727

2715

.75.

232

2Le

ptoI

I_sc

aff_

3_G

EN

E_3

2B

NR

dom

ain

prot

ein

398.

818

1748

.137

.425

.66

3.33

27.2

320

.62

Lept

oII_

scaf

f_3_

GE

NE

_36

6-py

ruvo

ylte

trahy

drop

terin

syn

thas

e14

5.7

1712

38.3

5.73

3.4

7.3

2Le

ptoI

I_sc

aff_

3_G

EN

E_3

7A

BC

tran

spor

ter A

TP-b

indi

ng p

rote

in37

8.3

6969

13.1

6.03

22

Lept

oII_

scaf

f_3_

GE

NE

_39

phen

ylal

anyl

-tRN

A s

ynth

etas

e, a

lpha

sub

unit

597

109

109

30.8

11.8

317

.17.

566

22

Lept

oII_

scaf

f_3_

GE

NE

_4un

ique

hyp

othe

tical

1611

49.7

15.2

42.7

329

.96

26.2

22

Lept

oII_

scaf

f_3_

GE

NE

_40

phen

ylal

anyl

-tRN

A s

ynth

etas

e, b

eta

subu

nit

635

9292

34.4

12.9

19.4

615

.63

19.9

22

Lept

oII_

scaf

f_3_

GE

NE

_41

ribos

omal

pro

tein

L20

1411

2525

46.6

30.2

29.7

16.9

29.9

629

.72

2Le

ptoI

I_sc

aff_

3_G

EN

E_4

2un

ique

hyp

othe

tical

(3-4

2, 1

107-

1)7

1250

.838

.46

3939

.540

22

Lept

oII_

scaf

f_3_

GE

NE

_43

trans

latio

n in

itiat

ion

fact

or IF

-3, N

-term

inal

dom

ain

(110

7-2,

3- 4

198

3939

53.1

25.9

23.6

323

.444

.56

402

2Le

ptoI

I_sc

aff_

3_G

EN

E_4

4un

ique

hyp

othe

tical

(tra

nsla

tion

initi

atio

n fa

ctor

IF-3

- tru

ncat

ed68

636

.212

.921

.87.

762

Lept

oII_

scaf

f_3_

GE

NE

_45

sens

ory

box/

GG

DE

F fa

mily

pro

tein

134

5.4

6231

13.1

1.16

7.26

1.26

22

Lept

oII_

scaf

f_3_

GE

NE

_46

phos

phom

ethy

lpyr

imid

ine

kina

se31

5.5

2927

11.7

3.9

22

Lept

oII_

scaf

f_3_

GE

NE

_47

pept

idas

e, M

23/M

37 fa

mily

32

1030

2621

.613

.16

9.8

7.2

22

Lept

oII_

scaf

f_3_

GE

NE

_49

thia

min

e bi

osyn

thes

is p

rote

in29

689

8977

.739

.53

48.7

548

.352

.92

2Le

ptoI

I_sc

aff_

3_G

EN

E_5

pept

idog

lyca

n as

soci

ate

lipop

rote

in19

923

2357

55.3

354

.249

.86

54.5

655

.92

2Le

ptoI

I_sc

aff_

3_G

EN

E_5

0ac

yl-c

oenz

yme

A s

ynth

etas

e71

6.2

00

3310

.86

19.9

37.

410

.52

2Le

ptoI

I_sc

aff_

3_G

EN

E_5

1la

ctoy

lglu

tath

ione

lyas

e 32

512

1228

.94.

1327

.424

.42

2Le

ptoI

I_sc

aff_

3_G

EN

E_5

6di

enel

acto

ne h

ydro

lase

297

2929

74.5

58.0

653

.03

19.4

64.7

352

.12

2Le

ptoI

I_sc

aff_

3_G

EN

E_5

7qu

inop

rote

in d

ehyd

roge

nase

/out

er m

embr

ane

prot

ein

5410

130

4942

.516

.720

39.5

8.23

10.5

22

Lept

oII_

scaf

f_3_

GE

NE

_58

uniq

ue h

ypot

hetic

al22

1040

.128

.56

20.5

334

.06

28.7

619

.2

22

Lept

oII_

scaf

f_3_

GE

NE

_59

two-

com

pone

nt s

enso

r his

tidin

e ki

nase

539.

362

2118

.64.

664.

12

2Le

ptoI

I_sc

aff_

3_G

EN

E_6

cons

erve

d hy

poth

etic

al (s

imila

r to

maj

or o

uter

mem

bran

e pr

ote

2611

107

47.8

42.4

34.4

621

.13

37.3

635

.82

2Le

ptoI

I_sc

aff_

3_G

EN

E_6

1un

ique

hyp

othe

tical

1710

4931

.36

22.1

17.6

327

.82

2Le

ptoI

I_sc

aff_

3_G

EN

E_6

2un

ique

hyp

othe

tical

429.

818

11.5

64.

267.

22

Lept

oII_

scaf

f_3_

GE

NE

_63

Zn-d

epen

dent

hyd

rola

ses

325.

818

1310

.65.

132

2Le

ptoI

I_sc

aff_

3_G

EN

E_6

4A

TP s

ynth

ase,

eps

ilon

subu

nit

165

1717

69.2

43.6

60.1

67.3

363

.62

2Le

ptoI

I_sc

aff_

3_G

EN

E_6

5A

TP s

ynth

ase,

bet

a su

buni

t50

50

087

.579

.86

81.4

62.

7383

.270

.92

2Le

ptoI

I_sc

aff_

3_G

EN

E_6

6A

TP s

ynth

ase,

gam

ma

subu

nit

3410

6060

64.6

53.9

649

.03

16.7

354

.76

51.2

22

Lept

oII_

scaf

f_3_

GE

NE

_67

ATP

syn

thas

e, a

lpha

sub

unit

546

171

171

60.7

49.4

346

.56

1.53

46.7

636

.12

2Le

ptoI

I_sc

aff_

3_G

EN

E_6

8un

ique

hyp

othe

tical

(lik

e A

TP s

ynth

ase,

del

ta s

ubun

it)20

56

637

.722

.530

.46

25.9

282

2Le

ptoI

I_sc

aff_

3_G

EN

E_6

9A

TP s

ynth

ase,

bet

a su

buni

t20

910

1061

.152

.56

45.9

333

.721

.12

Lept

oII_

scaf

f_3_

GE

NE

_70

ATP

syn

thas

e, H

+ tra

nspo

rting

, mito

chon

dria

l F0

com

plex

, sub

88.

112

1218

.46.

132

Lept

oII_

scaf

f_3_

GE

NE

_74

phos

phog

lyco

late

pho

spha

tase

275.

539

3911

.73.

767.

662

2Le

ptoI

I_sc

aff_

3_G

EN

E_7

7pe

ripla

smic

olig

opep

tide-

bind

ing

prot

ein

of o

ligop

eptid

e A

BC

t r60

1011

083

23.4

9.03

8.06

2.5

2Le

ptoI

I_sc

aff_

3_G

EN

E_7

9tri

ose

phop

hate

isom

eras

e28

5.4

3535

29.1

5.8

11.5

34.

132

Lept

oII_

scaf

f_3_

GE

NE

_8th

iam

ine-

mon

opho

spha

te k

inas

e37

5.2

2824

23.6

9.66

2.7

22

Lept

oII_

scaf

f_3_

GE

NE

_80

phos

phog

lyce

rate

kin

ase

436

129

129

72.2

49.0

661

.56

47.2

39.3

22

Lept

oII_

scaf

f_3_

GE

NE

_81

glyc

eral

dehy

de-3

-pho

spha

te d

ehyd

roge

nase

376

119

119

56.4

28.3

634

.13

44.7

333

.32

2Le

ptoI

I_sc

aff_

3_G

EN

E_8

2pe

nici

llin-

bind

ing

prot

ein

8910

142

140

48.7

24.7

18.6

318

.23

15.4

22

Lept

oII_

scaf

f_3_

GE

NE

_85

urid

ine

5-m

onop

hosp

hate

syn

thas

e23

740

4048

.619

.66

31.7

330

.518

.42

2Le

ptoI

I_sc

aff_

3_G

EN

E_8

6m

ethy

l-acc

eptin

g ch

emot

axis

pro

tein

345

4038

54.7

27.8

37.5

634

.86

22.8

2Le

ptoI

I_sc

aff_

3_G

EN

E_8

9ur

opor

phyr

in-II

I C-m

ethy

ltran

sfer

ase

249.

716

1415

.75.

235.

232

Lept

oII_

scaf

f_3_

GE

NE

_9A

TP-d

epen

dent

pro

teas

e La

928.

40

024

.43.

110

.66

5.5

22

Lept

oII_

scaf

f_3_

GE

NE

_90

com

pete

nce

prot

ein

Com

L32

9.9

2020

25.2

16.6

62.

932

Lept

oII_

scaf

f_3_

GE

NE

_92

nitro

gen

regu

latio

n pr

otei

n N

trX/s

igm

a-54

dep

ende

nt tr

ansc

ript

515.

512

911

110

.72.

261.

32

Lept

oII_

scaf

f_3_

GE

NE

_93

nitro

gen

regu

latio

n pr

otei

n N

trY84

812

110

412

.81.

433.

32

Lept

oII_

scaf

f_3_

GE

NE

_94

uniq

ue h

ypot

hetic

al45

119.

32.

361.

862

2Le

ptoI

I_sc

aff_

3_G

EN

E_9

5un

ique

hyp

othe

tical

255

42.3

10.5

310

.53

26.1

332

.92

Lept

oII_

scaf

f_3_

GE

NE

_97

uniq

ue h

ypot

hetic

al16

5.8

20.8

6.46

4.4

2Le

ptoI

I_sc

aff_

3_G

EN

E_9

8un

ique

hyp

othe

tical

319.

19

11.1

3.7

2Le

ptoI

I_sc

aff_

30_G

EN

E_1

(30-

1, 8

8-2)

am

idop

hosp

horib

osyl

trans

fera

se42

6.1

124

123

13.4

1.96

4.4

4.2

22

Lept

oII_

scaf

f_30

_GE

NE

_10

catio

n ef

flux

prot

ein

118

917

615

617

.47.

337.

434.

564.

32

Lept

oII_

scaf

f_30

_GE

NE

_11

trans

crip

tiona

l reg

ulat

or, L

ysR

346.

519

1925

.57.

6310

.63

22

Lept

oII_

scaf

f_30

_GE

NE

_12

oute

r mem

bran

e ef

flux

prot

ein

549

2525

32.8

15.5

315

.26

2.8

8.83

2Le

ptoI

I_sc

aff_

30_G

EN

E_1

4un

ique

hyp

othe

tical

239.

513

.55.

962

Lept

oII_

scaf

f_30

_GE

NE

_17

phen

ol h

ydro

xyla

se s

ubun

it P

hkF

286.

923

2321

4.26

6.5

6.63

2Le

ptoI

I_sc

aff_

30_G

EN

E_1

8un

ique

hyp

othe

tical

389.

413

.35.

33.

262

Lept

oII_

scaf

f_30

_GE

NE

_2ph

osph

orib

osyl

form

ylgl

ycin

amid

ine

synt

hase

II (8

8-1,

30-

2)68

5.7

115

108

23.4

8.83

8.66

22

Lept

oII_

scaf

f_30

_GE

NE

_22

cons

erve

d hy

poth

etic

al84

1050

47.1

40.3

32.5

20.2

34.5

23.3

22

Lept

oII_

scaf

f_30

_GE

NE

_23

plei

otro

pic

regu

lato

ry p

rote

in43

682

7421

.512

.718

.93

5.46

22

Lept

oII_

scaf

f_30

_GE

NE

_24

cons

erve

d hy

poth

etic

al19

623

40.5

11.5

620

.43

27.3

331

.627

.72

2Le

ptoI

I_sc

aff_

30_G

EN

E_2

6un

ique

hyp

othe

tical

135.

950

.919

.36

3040

302

2Le

ptoI

I_sc

aff_

30_G

EN

E_2

7un

ique

hyp

othe

tical

811

14.7

9.3

22

Lept

oII_

scaf

f_30

_GE

NE

_28

uniq

ue h

ypot

hetic

al32

966

.546

.836

.26

34.7

347

.06

20.8

22

Lept

oII_

scaf

f_30

_GE

NE

_29

uniq

ue h

ypot

hetic

al39

941

.426

.420

.516

.86

14.9

22

Lept

oII_

scaf

f_30

_GE

NE

_30

uniq

ue h

ypot

hetic

al12

5.3

100

75.7

62.9

388

.874

.82

2Le

ptoI

I_sc

aff_

30_G

EN

E_3

1se

nsor

y tra

nsdu

ctio

n hi

stid

ine

kina

se68

9.3

6764

5.9

1.96

22

Lept

oII_

scaf

f_30

_GE

NE

_32

two-

com

pone

nt re

spon

se re

gula

tor C

heY

175

4040

33.8

13.5

14.4

10.3

630

.218

.92

2Le

ptoI

I_sc

aff_

30_G

EN

E_3

3se

nsor

y bo

x/E

AL

dom

ain/

GG

DE

F do

mai

n98

510

581

20.4

3.93

9.86

3.9

22

Lept

oII_

scaf

f_30

_GE

NE

_35

biot

in c

arbo

xyla

se50

615

115

146

.512

.26

25.9

610

.46

10.5

22

Lept

oII_

scaf

f_30

_GE

NE

_36

biot

in c

arbo

xyl c

arrie

r pro

tein

174.

624

2133

.18.

912

.73

22.0

62

2Le

ptoI

I_sc

aff_

30_G

EN

E_3

7tra

nsla

tion

elon

gatio

n fa

ctor

215

5252

61.8

43.8

31.2

653

.93

50.8

2Le

ptoI

I_sc

aff_

30_G

EN

E_3

83-

dehy

droq

uina

te d

ehyd

rata

se, t

ype

II18

6.6

4141

25.6

3.16

14.8

62

2Le

ptoI

I_sc

aff_

30_G

EN

E_3

9co

nser

ved

hypo

thet

ical

515

1424

.49.

1311

.56

10.8

62

Lept

oII_

scaf

f_30

_GE

NE

_4ph

osph

orib

osyl

form

ylgl

ycin

amid

ine

synt

hase

com

pone

nt I

286.

659

5919

.64.

966.

5313

.06

2Le

ptoI

I_sc

aff_

30_G

EN

E_4

0fla

vopr

otei

n af

fect

ing

synt

hesi

s of

DN

A a

nd p

anto

then

ate

met

a45

6.6

8080

10.4

2.23

2.5

4.73

22

Lept

oII_

scaf

f_30

_GE

NE

_41

uniq

ue h

ypot

hetic

al16

545

.529

.83

30.5

620

.145

.545

.52

Lept

oII_

scaf

f_30

_GE

NE

_42

guan

ylat

e ki

nase

287.

845

4529

.68.

87.

134.

12

Lept

oII_

scaf

f_30

_GE

NE

_43

cons

erve

d hy

poth

etic

al10

5.2

1724

.58.

1624

.52

Lept

oII_

scaf

f_30

_GE

NE

_44

cons

erve

d hy

poth

etic

al34

5.8

2221

.83.

869.

810

.76.

8

2Le

ptoI

I_sc

aff_

30_G

EN

E_4

6ce

ll di

visi

on p

rote

in F

tsI

349.

253

248.

52.

832

2Le

ptoI

I_sc

aff_

30_G

EN

E_6

uniq

ue h

ypot

hetic

al26

540

.823

.06

40.8

16.9

630

.13

10.8

22

Lept

oII_

scaf

f_30

_GE

NE

_8ou

ter m

embr

ane

efflu

x pr

otei

n53

828

2832

.124

.73

25.8

36.

6617

.37.

32

2Le

ptoI

I_sc

aff_

30_G

EN

E_9

efflu

x tra

nspo

rter

4110

3030

32.4

20.7

623

.413

.63

24.4

621

22

Lept

oII_

scaf

f_30

3_G

EN

E_1

aden

ylyl

sulfa

te re

duct

ase,

sub

unit

A60

613

313

336

.211

.36

18.3

35.

22

2Le

ptoI

I_sc

aff_

303_

GE

NE

_3A

TP s

ulfu

ryla

se44

711

311

255

.219

.33

31.3

626

.13

11.7

22

Lept

oII_

scaf

f_30

3_G

EN

E_4

uniq

ue h

ypot

hetic

al (s

imila

r to

trans

crip

tiona

l reg

ulat

ors)

149.

77

436

.45.

88

19.8

2Le

ptoI

I_sc

aff_

303_

GE

NE

_6Fe

-S o

xido

redu

ctas

e/ba

cter

ioch

loro

phyl

l c8

met

hyltr

ansf

eras

e51

7.2

7440

25.4

7.46

9.43

10.2

32

2Le

ptoI

I_sc

aff_

317_

GE

NE

_1gl

ycyl

-tRN

A s

ynth

etas

e (9

4-19

, 317

-1)

306

3232

18.3

12.1

4.06

22

Lept

oII_

scaf

f_31

7_G

EN

E_4

biot

in s

ynth

etas

e 36

671

7128

.423

.46

187

2Le

ptoI

I_sc

aff_

317_

GE

NE

_56-

carb

oxyh

exan

oate

--C

oA li

gase

33

6.2

2120

19.1

10.2

32

Lept

oII_

scaf

f_31

7_G

EN

E_6

8-am

ino-

7-ox

onon

anoa

te s

ynth

ase

425.

764

6412

.90.

863.

432

2Le

ptoI

I_sc

aff_

317_

GE

NE

_7si

gnal

tran

sduc

tion

prot

ein/

inos

ine

mon

opho

spha

te d

ehyd

roge

155

1413

96.3

95.8

388

.73

35.7

696

.06

96.3

2Le

ptoI

I_sc

aff_

317_

GE

NE

_8ce

ll di

visi

on p

rote

in F

tsI

459.

560

2413

.74.

562

Lept

oII_

scaf

f_31

8_G

EN

E_3

Hel

ix-tu

rn-h

elix

pro

tein

, Cop

G fa

mily

98.

123

2320

.313

.53

2Le

ptoI

I_sc

aff_

318_

GE

NE

_4tra

nspo

sase

(2-8

, 318

-4)

538.

787

871.

70.

562

Lept

oII_

scaf

f_31

8_G

EN

E_7

uniq

ue h

ypot

hetic

al11

9.9

20.4

6.8

22

Lept

oII_

scaf

f_32

_GE

NE

_13

uniq

ue h

ypot

hetic

al36

963

.635

.36

35.8

324

.92

2Le

ptoI

I_sc

aff_

32_G

EN

E_1

4pe

ripla

smic

ser

ine

prot

ease

316

8478

53.4

31.8

631

.03

23.3

620

.92

2Le

ptoI

I_sc

aff_

32_G

EN

E_1

5un

ique

hyp

othe

tical

268

56.8

4.7

13.4

16.2

22

Lept

oII_

scaf

f_32

_GE

NE

_16

Hol

liday

junc

tion

DN

A h

elic

ase

376

9089

342.

118

.112

.13

22

Lept

oII_

scaf

f_32

_GE

NE

_17

Hol

liday

junc

tion

helic

ase

236

1515

45.7

4.63

19.2

23.5

322

.12

2Le

ptoI

I_sc

aff_

32_G

EN

E_1

8H

ollid

ay ju

nctio

n re

solv

ase

1910

1212

67.6

7.86

32.4

15.2

64.6

347

.82

2Le

ptoI

I_sc

aff_

32_G

EN

E_1

9try

psin

-like

ser

ine

prot

ease

5410

9292

7352

.848

.33

57.4

59.4

646

22

Lept

oII_

scaf

f_32

_GE

NE

_20

sigm

a-54

dep

ende

nt D

NA

-bin

ding

resp

onse

regu

lato

r 16

520

1945

.926

.56

22.3

2Le

ptoI

I_sc

aff_

32_G

EN

E_2

2he

xape

ptid

e tra

nsfe

rase

196

4844

35.6

4.9

4.33

5.46

22

Lept

oII_

scaf

f_32

_GE

NE

_23

beta

-pho

spho

gluc

omut

ase

255.

128

1739

.13.

6323

.03

25.2

22

Lept

oII_

scaf

f_32

_GE

NE

_24

uniq

ue h

ypot

hetic

al24

513

138.

664.

3313

132

2Le

ptoI

I_sc

aff_

32_G

EN

E_2

5co

nser

ved

hypo

thet

ical

(BN

R d

omai

n pr

otei

n )

377

3456

42.8

630

.86

48.4

644

.513

.72

2Le

ptoI

I_sc

aff_

32_G

EN

E_2

6un

ique

hyp

othe

tical

246

61.5

20.3

626

.139

.26

2Le

ptoI

I_sc

aff_

32_G

EN

E_2

7un

ique

hyp

othe

tical

(con

tain

s do

mai

n fo

und

in s

mal

l sol

uble

pr

137

28.4

12.9

32

2Le

ptoI

I_sc

aff_

32_G

EN

E_2

8un

ique

hyp

othe

tical

157

82.8

19.6

626

.13

56.4

659

.72

2Le

ptoI

I_sc

aff_

32_G

EN

E_3

3co

nser

ved

hypo

thet

ical

(lik

e G

GD

EF

dom

ain

prot

eins

) 43

923

642

.318

.827

.63

24.7

625

.22

2Le

ptoI

I_sc

aff_

32_G

EN

E_3

4m

ethi

onin

e ga

mm

a ly

ase

446.

995

9348

.614

.89.

967.

232

2Le

ptoI

I_sc

aff_

32_G

EN

E_3

6un

ique

hyp

othe

tical

554

18.7

18.7

18.7

3.33

1512

.42

Lept

oII_

scaf

f_32

_GE

NE

_37

amm

oniu

m tr

ansp

orte

r 50

6.1

117

110

8.2

5.46

7.3

22

Lept

oII_

scaf

f_32

_GE

NE

_38

nitro

gen

regu

lato

ry p

rote

in P

-II (G

ln s

ynth

etas

e re

gula

tor)

129

3030

98.2

85.4

76.4

627

.491

.66

96.4

2Le

ptoI

I_sc

aff_

32_G

EN

E_3

9am

mon

ium

tran

spor

ter A

MT2

466

136

130

6.7

2.23

22

Lept

oII_

scaf

f_32

_GE

NE

_4un

ique

hyp

othe

tical

(100

2-4,

32-

4)4

527

.59.

162

2Le

ptoI

I_sc

aff_

32_G

EN

E_4

0ca

tion

trans

port

ATP

ase

907

133

119

47.6

1924

.66

6.13

9.83

7.8

2Le

ptoI

I_sc

aff_

32_G

EN

E_4

2un

ique

hyp

othe

tical

299.

68

7.5

2.5

2Le

ptoI

I_sc

aff_

32_G

EN

E_4

4en

donu

clea

se

2311

1210

13.3

4.43

22

Lept

oII_

scaf

f_32

_GE

NE

_45

thio

ldis

ufid

e is

omer

ase

168

2525

55.3

2828

.46

50.4

648

.66

382

2Le

ptoI

I_sc

aff_

32_G

EN

E_4

6am

inop

eptid

ase

986

018

043

.517

.63

27.5

7.63

22

Lept

oII_

scaf

f_32

_GE

NE

_47

uniq

ue h

ypot

hetic

al (s

imila

r to

mol

ybde

num

cof

acto

r car

rier p

r o26

5.7

96

39.7

11.8

313

.93

22.2

17.2

2Le

ptoI

I_sc

aff_

32_G

EN

E_4

9ex

cinu

clea

se A

BC

, B s

ubun

it80

5.9

00

17.8

2.9

5.9

22

Lept

oII_

scaf

f_32

_GE

NE

_52

oute

r mem

bran

e ef

flux

prot

ein

5310

1919

51.1

40.4

626

.33

3.8

25.5

22

Lept

oII_

scaf

f_32

_GE

NE

_53

efflu

x tra

nspo

rter (

32-5

3, 2

1-60

)35

1026

2676

.647

.83

53.6

616

.640

.727

.62

2Le

ptoI

I_sc

aff_

32_G

EN

E_5

4ca

tion

efflu

x sy

stem

(32-

52, 2

1-59

)21

1040

3135

.822

.321

.22

Lept

oII_

scaf

f_32

_GE

NE

_6co

nser

ved

hypo

thet

ical

(sim

ilar t

o Fe

-S o

xido

redu

ctas

e)35

5.8

316

13.5

4.5

22

Lept

oII_

scaf

f_32

_GE

NE

_8TR

AP

sig

nal t

rans

duct

ion

prot

ein

126

2611

56.7

27.2

10.9

2523

.12

Lept

oII_

scaf

f_33

_GE

NE

_14

uniq

ue h

ypot

hetic

al30

9.9

13.9

8.53

3.3

2Le

ptoI

I_sc

aff_

33_G

EN

E_1

6se

nsor

y bo

x (G

GD

EF/

EA

L do

mai

n) re

gula

tory

pro

tein

477.

239

395.

61.

862

2Le

ptoI

I_sc

aff_

33_G

EN

E_1

9un

ique

hyp

othe

tical

409.

25

52.2

39.6

12.2

22.4

312

.52

Lept

oII_

scaf

f_33

_GE

NE

_2cy

toch

rom

e c

oxid

ase

(33-

2, 3

3-1,

23-

53)

319

4343

29.3

24.5

320

.22

Lept

oII_

scaf

f_33

_GE

NE

_20

uniq

ue h

ypot

hetic

al54

5.6

12.2

3.56

1.5

2Le

ptoI

I_sc

aff_

33_G

EN

E_2

2B

and

7 pr

otei

n/m

embr

ane

prot

ease

sub

unit

287.

985

8414

.34.

762

Lept

oII_

scaf

f_33

_GE

NE

_23

uniq

ue h

ypot

hetic

al16

5.9

725

.38.

432

2Le

ptoI

I_sc

aff_

33_G

EN

E_2

4un

ique

hyp

othe

tical

205

6221

.442

.26

46.5

333

.52

2Le

ptoI

I_sc

aff_

33_G

EN

E_2

5ox

idor

educ

tase

336

2725

51.9

18.5

36.4

615

.83

12.3

22

Lept

oII_

scaf

f_33

_GE

NE

_27

uniq

ue h

ypot

hetic

al21

550

.88.

97.

516

.420

.92

2Le

ptoI

I_sc

aff_

33_G

EN

E_3

0si

gma-

54 d

epen

dent

DN

A-b

indi

ng re

spon

se re

gula

tor

546

9996

62.2

27.1

633

.214

.13

9.6

22

Lept

oII_

scaf

f_33

_GE

NE

_31

sens

ory

box

hist

idin

e ki

nase

747

5233

59.8

18.6

624

.63

12.0

67.

72

2Le

ptoI

I_sc

aff_

33_G

EN

E_3

2co

nser

ved

hypo

thet

ical

937

054

.633

.03

33.9

25.0

622

22

Lept

oII_

scaf

f_33

_GE

NE

_36

dihy

drox

yaci

d de

hydr

atas

e59

60

064

.932

.16

45.7

32.4

617

.32

Lept

oII_

scaf

f_33

_GE

NE

_37

Sua

5 pr

otei

n tra

nsla

tion

fact

or37

6.5

7146

13.9

3.33

4.63

22

Lept

oII_

scaf

f_33

_GE

NE

_38

dihy

drox

yaci

d de

hydr

atas

e/ph

osph

oglu

cona

te d

ehyd

rata

se59

60

026

.510

.811

.42.

932

Lept

oII_

scaf

f_33

_GE

NE

_39

cons

erve

d hy

poth

etic

al32

6.1

5011

.83.

932

Lept

oII_

scaf

f_33

_GE

NE

_4un

ique

hyp

othe

tical

(sim

ilar t

o tw

in a

rgin

ine

trans

loca

tion

prot

e8

9.3

435

.611

.86

22

Lept

oII_

scaf

f_33

_GE

NE

_41

cons

erve

d hy

poth

etic

al92

70

64.6

36.2

640

.417

.53

17.5

2Le

ptoI

I_sc

aff_

33_G

EN

E_5

uniq

ue h

ypot

hetic

al16

7.1

539

.213

.06

2Le

ptoI

I_sc

aff_

33_G

EN

E_8

NA

DH

:flav

in o

xido

redu

ctas

e/xe

nobi

otic

redu

ctas

e39

712

511

045

.510

.56

19.5

15.8

32

2Le

ptoI

I_sc

aff_

333_

GE

NE

_8un

ique

hyp

othe

tical

4510

58.4

45.4

36.2

16.0

322

.79.

92

2Le

ptoI

I_sc

aff_

333_

GE

NE

_9un

ique

hyp

othe

tical

138

61.5

57.1

356

.56

47.2

653

.353

.32

Lept

oII_

scaf

f_34

1_G

EN

E_1

0co

nser

ved

hypo

thet

ical

197.

960

26.4

5.86

7.33

2Le

ptoI

I_sc

aff_

341_

GE

NE

_11

cons

erve

d hy

poth

etic

al25

6.7

557.

12.

362

2Le

ptoI

I_sc

aff_

349_

GE

NE

_1rib

osom

al p

rote

in S

516

1043

4368

.235

.741

.145

.954

.555

.62

2Le

ptoI

I_sc

aff_

349_

GE

NE

_10

ribos

omal

pro

tein

L22

1211

1818

54.5

30.9

5048

.850

22

Lept

oII_

scaf

f_34

9_G

EN

E_1

1rib

osom

al p

rote

in S

1911

1127

2760

.635

.826

.356

.760

.62

2Le

ptoI

I_sc

aff_

349_

GE

NE

_12

ribos

omal

pro

tein

L2

3010

8888

78.8

54.6

57.6

46.3

63.5

69.2

22

Lept

oII_

scaf

f_34

9_G

EN

E_1

3rib

osom

al p

rote

in L

424

9.4

4040

53.2

4334

.443

.743

.62

2Le

ptoI

I_sc

aff_

349_

GE

NE

_14

ribos

omal

pro

tein

L3

911

2121

83.9

32.2

46.4

37.4

49.8

74.7

22

Lept

oII_

scaf

f_34

9_G

EN

E_2

ribos

omal

pro

tein

L18

1310

2828

57.3

11.1

2718

.316

23.9

22

Lept

oII_

scaf

f_34

9_G

EN

E_3

ribos

omal

pro

tein

L6

2010

4040

59.2

28.5

35.8

43.4

51.6

59.2

22

Lept

oII_

scaf

f_34

9_G

EN

E_4

ribos

omal

pro

tein

S8

159.

631

3141

.730

33.8

34.4

35.6

22

Lept

oII_

scaf

f_34

9_G

EN

E_5

ribos

omal

pro

tein

L5

259.

959

5957

.132

.744

.216

.750

46.9

22

Lept

oII_

scaf

f_34

9_G

EN

E_6

ribos

omal

pro

tein

L14

1310

4242

79.5

36.1

51.4

49.2

64.8

22

Lept

oII_

scaf

f_34

9_G

EN

E_7

uniq

ue h

ypot

hetic

al (s

imila

r to

ribos

omal

pro

tein

S17

)11

118

862

.14.

649

.113

.760

.760

22

Lept

oII_

scaf

f_34

9_G

EN

E_8

ribos

omal

pro

tein

L16

1510

4545

69.6

34.8

51.2

2856

.356

.52

2Le

ptoI

I_sc

aff_

349_

GE

NE

_9rib

osom

al p

rote

in S

321

1057

5772

.655

.250

.438

.556

.456

.52

Lept

oII_

scaf

f_35

6_G

EN

E_1

mem

bran

e-fu

sion

pro

tein

, RN

D-li

ke e

fflux

sys

tem

com

pone

nt45

1062

627.

91.

41.

82

Lept

oII_

scaf

f_35

6_G

EN

E_2

oute

r mem

bran

e he

avy

met

al e

fflux

pro

tein

4210

1514

4.9

2.36

3.26

1.63

2Le

ptoI

I_sc

aff_

369_

GE

NE

_7un

deca

pren

ol-p

hosp

hate

gal

acto

seph

osph

otra

nsfe

rase

/O-a

nti g

609.

763

634.

11.

362

Lept

oII_

scaf

f_37

4_G

EN

E_1

0co

nser

ved

hypo

thet

ical

158.

247

18.5

6.16

22

Lept

oII_

scaf

f_37

4_G

EN

E_2

trans

posa

se-li

ke (3

74-2

, 753

-5)

266

1010

90.9

13.1

346

.76

66.3

655

22

Lept

oII_

scaf

f_37

4_G

EN

E_3

trans

posa

se (1

91-7

, 73-

35, 3

74-3

)17

8.9

3329

73.3

26.2

612

.56

5.26

44.3

44.5

2Le

ptoI

I_sc

aff_

374_

GE

NE

_6un

ique

hyp

othe

tical

255.

418

102

2Le

ptoI

I_sc

aff_

374_

GE

NE

_7un

ique

hyp

othe

tical

1811

254

24.7

326

.248

.46

36.6

44.8

2Le

ptoI

I_sc

aff_

374_

GE

NE

_8un

ique

hyp

othe

tical

415.

67

15.9

10.6

3.7

22

Lept

oII_

scaf

f_4_

GE

NE

_1ou

ter m

embr

ane

efflu

x pr

otei

n (4

-1, 5

9-29

)49

8.2

1613

57.3

35.7

633

.26

26.9

317

.72

2Le

ptoI

I_sc

aff_

4_G

EN

E_1

00co

nser

ved

hypo

thet

ical

116

1280

52.9

652

.668

.06

50.5

22

Lept

oII_

scaf

f_4_

GE

NE

_11

cons

erve

d hy

poth

etic

al (s

imila

r to

cyto

chro

me

c bi

ogen

esis

thi o

545

108

739

.99.

29.

365.

662

2Le

ptoI

I_sc

aff_

4_G

EN

E_1

3S

AM

-dep

ende

nt m

ethy

ltran

sfer

ase

317

3735

46.4

6.76

18.7

320

.76

30.1

22

Lept

oII_

scaf

f_4_

GE

NE

_14

uniq

ue h

ypot

hetic

al12

980

.224

.43

18.5

51.5

66.3

22

Lept

oII_

scaf

f_4_

GE

NE

_15

sulfu

ryla

se13

920

2066

.740

.06

32.1

620

.16

52.6

350

22

Lept

oII_

scaf

f_4_

GE

NE

_16

uniq

ue h

ypot

hetic

al52

1084

.462

.659

.16

73.4

663

.86

582

2Le

ptoI

I_sc

aff_

4_G

EN

E_1

7co

nser

ved

hypo

thet

ical

(AB

C tr

ansp

orte

r, pe

ripla

smic

com

pon e

3711

709

53.7

29.9

35.8

23.1

26.1

630

.72

Lept

oII_

scaf

f_4_

GE

NE

_18

uniq

ue h

ypot

hetic

al20

4.8

64

22

Lept

oII_

scaf

f_4_

GE

NE

_2ca

tion

efflu

x pr

otei

n42

837

3758

.715

.43

25.6

343

.33

32.7

32

2Le

ptoI

I_sc

aff_

4_G

EN

E_2

1un

ique

hyp

othe

tical

(pep

tidyl

-pro

lyl c

is-tr

ans

isom

eras

e-lik

e)27

9.2

77

76.5

38.7

351

.13

22.0

613

.72

2Le

ptoI

I_sc

aff_

4_G

EN

E_2

2gl

ycin

e cl

eava

ge s

yste

m T

pro

tein

41

660

5843

.226

.26

21.2

17.0

311

.12

2Le

ptoI

I_sc

aff_

4_G

EN

E_2

3gl

ycin

e cl

eava

ge s

yste

m p

rote

in15

525

2593

.360

.215

.93

61.7

74.1

335

.12

2Le

ptoI

I_sc

aff_

4_G

EN

E_2

4gl

ycin

e cl

eava

ge s

yste

m P

pro

tein

, sub

unit

147

697

9356

.921

.26

23.6

18.5

316

.22

2Le

ptoI

I_sc

aff_

4_G

EN

E_2

5gl

ycin

e de

hydr

ogen

ase

547

126

126

67.1

33.3

330

.66

28.7

29.6

22

Lept

oII_

scaf

f_4_

GE

NE

_27

uniq

ue h

ypot

hetic

al13

872

.611

.222

.444

.23

57.5

22

Lept

oII_

scaf

f_4_

GE

NE

_29

cons

erve

d hy

poth

etic

al (s

igna

l tra

nsdu

ctio

n H

D d

omai

n)31

527

28.1

7.23

19.4

312

.72

Lept

oII_

scaf

f_4_

GE

NE

_3m

etal

effl

ux s

yste

m p

rote

in11

59

00

16.4

3.86

6.06

32

Lept

oII_

scaf

f_4_

GE

NE

_31

trans

crip

tiona

l reg

ulat

or F

leQ

/resp

onse

regu

lato

r38

5.9

8585

40.4

22.2

2Le

ptoI

I_sc

aff_

4_G

EN

E_3

2un

ique

hyp

othe

tical

8210

35.7

10.5

37.

11.

934.

62

Lept

oII_

scaf

f_4_

GE

NE

_33

sens

ory

box

hist

idin

e ki

nase

455.

231

3028

.84.

836.

73

2Le

ptoI

I_sc

aff_

4_G

EN

E_3

4si

gma-

54 d

epen

dent

resp

onse

regu

lato

r54

5.9

9794

14.7

4.9

2Le

ptoI

I_sc

aff_

4_G

EN

E_3

6fla

gella

r bas

al-b

ody

rod

prot

ein

FlgC

16

9.2

2626

20.7

6.9

22

Lept

oII_

scaf

f_4_

GE

NE

_38

flage

llar M

-rin

g pr

otei

n Fl

iF59

9.8

7272

36.2

7.4

12.0

38.

32

Lept

oII_

scaf

f_4_

GE

NE

_39

flage

llar m

otor

sw

itch

prot

ein

FliG

374.

959

5940

.111

.49.

612

.82

2Le

ptoI

I_sc

aff_

4_G

EN

E_4

0un

ique

hyp

othe

tical

255

44.7

4.26

8.66

27.5

62

Lept

oII_

scaf

f_4_

GE

NE

_43

uniq

ue h

ypot

hetic

al19

117

20.7

9.06

2Le

ptoI

I_sc

aff_

4_G

EN

E_4

4un

ique

hyp

othe

tical

529.

720

.212

22

Lept

oII_

scaf

f_4_

GE

NE

_45

flage

llar h

ook

prot

ein

3010

2121

51.1

26.4

35.

825

.36

22.8

22

Lept

oII_

scaf

f_4_

GE

NE

_46

flage

llar h

ook

prot

ein

4810

5050

63.5

55.5

342

.53

23.1

41.6

331

.12

2Le

ptoI

I_sc

aff_

4_G

EN

E_4

7fla

gella

r pro

tein

FliL

19

616

1250

2426

.76

31.5

633

.36

22

Lept

oII_

scaf

f_4_

GE

NE

_48

flage

llar m

otor

sw

itch

144

2424

6441

.623

.73

30.6

657

.86

562

2Le

ptoI

I_sc

aff_

4_G

EN

E_4

9un

ique

hyp

othe

tical

(sim

ilar t

o fla

gella

r ass

embl

y pr

otei

n Fl

iO)

1911

55

38.7

15.6

6.16

2Le

ptoI

I_sc

aff_

4_G

EN

E_5

dnaK

sup

pres

sor p

rote

in15

5.2

1818

52.8

17.3

7.86

35.7

46.5

2Le

ptoI

I_sc

aff_

4_G

EN

E_5

4fla

gella

r bio

synt

hetic

pro

tein

Flh

A76

6.2

00

19.9

1.9

8.56

1.93

2Le

ptoI

I_sc

aff_

4_G

EN

E_5

5fla

gella

r bio

synt

hetic

pro

tein

Flh

F43

5.6

4040

13.5

4.5

22

Lept

oII_

scaf

f_4_

GE

NE

_56

chro

mos

ome

parti

tioni

ng A

TPas

e32

561

6163

.739

.644

.73

44.1

620

.22

2Le

ptoI

I_sc

aff_

4_G

EN

E_5

7R

NA

pol

ymer

ase

sigm

a fa

ctor

for f

lage

llar o

pero

n 29

544

4456

.229

.925

.113

.410

.82

Lept

oII_

scaf

f_4_

GE

NE

_58

chem

otax

is p

rote

in m

ethy

ltran

sfer

ase

Che

R

308

3131

22

Lept

oII_

scaf

f_4_

GE

NE

_59

chem

otax

is re

gula

tor p

rote

in C

heY

148.

142

4269

49.2

53.9

658

.96

692

2Le

ptoI

I_sc

aff_

4_G

EN

E_6

0ch

emot

axis

his

tidin

e ki

nase

705

141

141

54.3

31.2

338

.66

14.2

6.8

22

Lept

oII_

scaf

f_4_

GE

NE

_61

prot

ein-

glut

amat

e m

ethy

lest

eras

e 36

646

4622

.19.

034.

062

2Le

ptoI

I_sc

aff_

4_G

EN

E_6

2m

ethy

l-acc

eptin

g ch

emot

axis

pro

tein

619

5454

51.7

30.6

638

.33

19.4

610

.62

2Le

ptoI

I_sc

aff_

4_G

EN

E_6

3pu

rine-

bind

ing

chem

otax

is p

rote

in, C

heW

195

2221

74.9

25.5

647

.76

29.6

32

Lept

oII_

scaf

f_4_

GE

NE

_64

flage

llar m

otor

pro

tein

, Mot

A28

5.6

5555

14.6

2.43

5.63

3.46

2Le

ptoI

I_sc

aff_

4_G

EN

E_6

5ch

emot

axis

mot

B p

rote

in29

1141

4025

.38.

811

.46

22

Lept

oII_

scaf

f_4_

GE

NE

_67

uniq

ue h

ypot

hetic

al20

646

.226

.53

26.5

62

2Le

ptoI

I_sc

aff_

4_G

EN

E_7

uniq

ue h

ypot

hetic

al32

94

73.2

70.2

56.8

318

.93

52.8

332

.72

2Le

ptoI

I_sc

aff_

4_G

EN

E_7

0de

hydr

ogen

ase

259

3030

75.3

23.5

634

.03

43.8

622

.12

2Le

ptoI

I_sc

aff_

4_G

EN

E_7

6am

inot

rans

fera

se47

913

113

167

.843

.66

45.4

344

.13

32.2

22

Lept

oII_

scaf

f_4_

GE

NE

_8di

amin

opim

elat

e ep

imer

ase

326

5454

61.4

35.4

46.7

630

.66

43.4

2Le

ptoI

I_sc

aff_

4_G

EN

E_8

1co

nser

ved

hypo

thet

ical

1910

1241

.128

.36

12.9

614

.06

16.6

22

Lept

oII_

scaf

f_4_

GE

NE

_82

uniq

ue h

ypot

hetic

al12

554

.241

.73

35.2

43.9

23.4

22

Lept

oII_

scaf

f_4_

GE

NE

_83

uniq

ue h

ypot

hetic

al16

1131

.710

.36

21.6

22.3

22

Lept

oII_

scaf

f_4_

GE

NE

_86

AB

C tr

ansp

orte

r18

518

1681

.246

.23

17.4

675

.461

.543

.12

Lept

oII_

scaf

f_4_

GE

NE

_87

uniq

ue h

ypot

hetic

al10

8.2

22.2

7.4

22

Lept

oII_

scaf

f_4_

GE

NE

_89

DN

A to

pois

omer

ase

I94

90

050

.810

.33

20.8

69.

4612

.92

Lept

oII_

scaf

f_4_

GE

NE

_90

gluc

ose-

inhi

bite

d di

visi

on p

rote

in A

516.

710

210

219

.19.

335.

232

2Le

ptoI

I_sc

aff_

4_G

EN

E_9

2he

at s

hock

pro

teas

e19

650

5066

.128

.521

.63

51.2

660

.62

2Le

ptoI

I_sc

aff_

4_G

EN

E_9

3A

TP-d

epen

dant

Hsl

U p

rote

ase

496

111

108

327

16.7

68.

532

2Le

ptoI

I_sc

aff_

4_G

EN

E_9

4ac

etyl

glu

tam

ate

kina

se31

674

7453

.818

.533

.828

.36

31.4

22

Lept

oII_

scaf

f_4_

GE

NE

_95

uniq

ue h

ypot

hetic

al17

1255

.120

.343

.36

39.3

22

Lept

oII_

scaf

f_4_

GE

NE

_96

deox

yurid

inet

ripho

spha

tase

17

639

3970

.145

.23

50.5

329

.92

Lept

oII_

scaf

f_4_

GE

NE

_97

corr

in/p

orph

yrin

met

hyltr

ansf

eras

e30

855

4639

.413

.12

Lept

oII_

scaf

f_4_

GE

NE

_98

pant

oate

--be

ta-a

lani

ne li

gase

326

5655

16.1

5.46

2.66

22

Lept

oII_

scaf

f_4_

GE

NE

_99

carb

on-n

itrog

en h

ydro

lase

dom

ain

308

4619

41.4

14.0

321

.46

19.3

32

2Le

ptoI

I_sc

aff_

402_

GE

NE

_2A

TPas

e in

volv

ed in

AB

C tr

ansp

orte

rs25

643

4318

.19.

512

.58

5.4

22

Lept

oII_

scaf

f_41

_GE

NE

_15

catio

nic

amin

o ac

id tr

ansp

orte

r (ca

t-1)

7510

6934

10.9

5.33

6.46

4.93

22

Lept

oII_

scaf

f_41

_GE

NE

_16

uniq

ue h

ypot

hetic

al53

47

20.3

15.3

318

.56

12.1

2Le

ptoI

I_sc

aff_

41_G

EN

E_1

9K

+-tra

nspo

rting

ATP

ase

B c

hain

716.

10

04.

91.

632

2Le

ptoI

I_sc

aff_

41_G

EN

E_2

chem

otax

is p

rote

in C

heY

/tran

scrip

tiona

l reg

ulat

or50

710

610

611

2.8

5.13

2Le

ptoI

I_sc

aff_

41_G

EN

E_2

5po

tass

ium

-tran

spor

ting

P-ty

pe A

TPas

e D

cha

in83

9.3

109

109

5.1

1.2

1.2

22

Lept

oII_

scaf

f_41

_GE

NE

_27

uniq

ue h

ypot

hetic

al33

1041

.26.

9614

.332

.56

11.4

22

Lept

oII_

scaf

f_41

_GE

NE

_28

beta

-hyd

roxy

acid

deh

ydro

gena

ses

336

5555

25.7

2.7

4.23

17.9

8.1

2Le

ptoI

I_sc

aff_

41_G

EN

E_2

9ba

cter

iofe

rriti

n co

mig

rato

ry p

rote

in/p

erox

iredo

xin

2110

4237

37.7

4.53

4.36

21.1

319

.42

2Le

ptoI

I_sc

aff_

41_G

EN

E_3

1su

ccin

yl-C

oA s

ynth

etas

e/ac

yl-C

oA s

ynth

etas

e 16

624

2419

.610

.86.

764.

2612

.82

2Le

ptoI

I_sc

aff_

41_G

EN

E_3

4co

nser

ved

hypo

thet

ical

246

4748

.621

.826

.235

.53

24.3

22

Lept

oII_

scaf

f_41

_GE

NE

_35

cyst

eine

des

ulfh

ydra

se42

766

6627

.94.

320

9.3

8.2

22

Lept

oII_

scaf

f_41

_GE

NE

_36

NA

DH

deh

ydro

gena

se (u

biqu

inon

e) 1

alp

ha s

ubco

mpl

ex33

9.4

4836

37.6

22.0

322

.13

23.0

62

Lept

oII_

scaf

f_41

_GE

NE

_7(8

20-1

, 41-

7) s

ulfid

e-qu

inon

e re

duct

ase

468.

615

915

732

.83.

72.

368.

7312

.32

2Le

ptoI

I_sc

aff_

41_G

EN

E_9

uniq

ue h

ypot

hetic

al16

844

.727

.76

24.2

38.

4619

.76

23.3

22

Lept

oII_

scaf

f_41

0_G

EN

E_3

uniq

ue h

ypot

hetic

al (4

10-3

, 134

-13)

127.

940

18.4

25.4

30.4

620

2Le

ptoI

I_sc

aff_

410_

GE

NE

_4U

DP

-gal

acto

se-li

pid

carr

ier t

rans

fera

se (1

34-1

4, 4

10-4

)32

970

3730

.14.

67.

132

2Le

ptoI

I_sc

aff_

410_

GE

NE

_5pr

otei

n di

sulfi

de is

omer

ase

(134

-15,

410

-5)

368

1010

71.1

49.1

336

.770

.960

.73

42.8

22

Lept

oII_

scaf

f_41

0_G

EN

E_6

chem

otax

is p

rote

in C

heV

36

618

1849

.425

.23

30.2

622

.523

.32

2Le

ptoI

I_sc

aff_

410_

GE

NE

_7co

nser

ved

hypo

thet

ical

238

1721

.53.

517

.33

11.6

62

2Le

ptoI

I_sc

aff_

410_

GE

NE

_8un

ique

hyp

othe

tical

89

28.4

28.4

9.46

28.4

2Le

ptoI

I_sc

aff_

412_

GE

NE

_1tra

nspo

sase

(17

3-15

, 261

-8, 2

65-1

1, 4

12-1

)49

9.7

138

127

10.9

3.63

1.46

22

Lept

oII_

scaf

f_41

2_G

EN

E_2

trans

posa

se-li

ke (7

3-38

, 173

-16,

412

-2, 2

65-1

0, 2

61-9

)25

5.4

3838

71.4

34.1

330

.254

.43

37.1

2Le

ptoI

I_sc

aff_

42_G

EN

E_1

0ch

aper

one

prot

ein

Hsc

B25

5.7

3838

25.8

4.73

3.86

12.4

22

Lept

oII_

scaf

f_42

_GE

NE

_11

chap

eron

e pr

otei

n dn

aK

416

8080

49.7

21.9

29.9

628

.36

22.1

22

Lept

oII_

scaf

f_42

_GE

NE

_12

chap

eron

e pr

otei

n H

scA

24

644

4343

.515

.13

20.3

619

.43

2Le

ptoI

I_sc

aff_

42_G

EN

E_1

32F

e-2S

ferr

edox

in11

525

2521

.414

.26

2Le

ptoI

I_sc

aff_

42_G

EN

E_1

4co

nser

ved

hypo

thet

ical

84.

522

25.4

8.46

22

Lept

oII_

scaf

f_42

_GE

NE

_16

ATP

ase

invo

lved

in c

hrom

osom

e pa

rtitio

ning

386

9191

77.4

37.1

651

.315

.747

.427

.42

2Le

ptoI

I_sc

aff_

42_G

EN

E_1

9co

nser

ved

hypo

thet

ical

(sim

ilar t

o ga

mm

a-bu

tyro

beta

ine

hydr

o12

6.4

107

50.5

36.9

4.53

19.7

32

2Le

ptoI

I_sc

aff_

42_G

EN

E_2

uniq

ue h

ypot

hetic

al4

5.8

22.5

1522

.515

22

Lept

oII_

scaf

f_42

_GE

NE

_20

glyc

erol

-3-p

hosp

hate

deh

ydro

gena

se

387

7474

42.5

9.06

19.2

321

.16

2Le

ptoI

I_sc

aff_

42_G

EN

E_2

1ph

osph

orib

osyl

trans

fera

se

245.

835

3551

.66.

2617

.52

2Le

ptoI

I_sc

aff_

42_G

EN

E_2

4ph

osph

olip

id b

indi

ng p

rote

in20

1045

4524

.520

.42

2Le

ptoI

I_sc

aff_

42_G

EN

E_2

5se

ryl-t

RN

A s

ynth

etas

e50

5013

012

966

.134

.56

39.4

630

.36

21.7

22

Lept

oII_

scaf

f_42

_GE

NE

_26

uniq

ue h

ypot

hetic

al14

838

.222

.23

5.43

29.8

322

22

Lept

oII_

scaf

f_42

_GE

NE

_27

uniq

ue h

ypot

hetic

al27

938

.210

.95.

833

.33

12.0

322

22

Lept

oII_

scaf

f_42

_GE

NE

_29

GTP

ases

(42-

29, 4

6-22

, 944

-1)

607

9999

25.8

2.26

9.73

2Le

ptoI

I_sc

aff_

42_G

EN

E_3

hem

olys

in51

5.3

7963

43.3

1223

.43

5.36

22

Lept

oII_

scaf

f_42

_GE

NE

_32

uniq

ue h

ypot

hetic

al16

685

.735

22.1

336

.285

.72

2Le

ptoI

I_sc

aff_

42_G

EN

E_3

3pe

ptid

ase

549

7575

65.1

36.0

330

.76

51.3

47.7

617

22

Lept

oII_

scaf

f_42

_GE

NE

_34

zinc

-dep

enda

nt p

eptid

ase

529

6666

74.8

59.3

50.7

31.8

654

.66

52.2

2Le

ptoI

I_sc

aff_

42_G

EN

E_4

uniq

ue h

ypot

hetic

al21

7.2

27.5

2.1

7.06

22

Lept

oII_

scaf

f_42

_GE

NE

_5un

ique

hyp

othe

tical

4010

16.9

12.9

62

2Le

ptoI

I_sc

aff_

42_G

EN

E_7

cyst

eine

des

ulfu

ryla

se45

613

713

772

.841

.03

45.4

39.2

35.9

22

Lept

oII_

scaf

f_42

_GE

NE

_8ni

fU h

omol

og in

volv

ed in

mat

urat

ion

of F

e-S

clu

ster

s15

549

4968

.626

.06

6.33

52.0

642

.32

Lept

oII_

scaf

f_42

_GE

NE

_9H

esB

/iron

-sul

fur c

lust

er a

ssem

bly

acce

ssor

y pr

otei

n12

5.1

3834

11.9

3.96

2Le

ptoI

I_sc

aff_

426_

GE

NE

_2Fe

-S o

xido

redu

ctas

e/m

ethy

ltran

sfer

ase

716.

560

6039

.813

.66

17.1

36.

632

2Le

ptoI

I_sc

aff_

426_

GE

NE

_3rib

osom

al p

rote

in L

1317

1055

3766

.242

.36

42.6

28.9

356

.26

64.9

22

Lept

oII_

scaf

f_42

6_G

EN

E_4

ribos

omal

pro

tein

S9

1511

3131

8031

.63

45.4

322

.23

43.7

374

.82

Lept

oII_

scaf

f_42

6_G

EN

E_5

N-a

cety

l-gam

ma-

glut

amyl

-pho

spha

te re

duct

ase

387.

264

6415

.32.

737.

862

2Le

ptoI

I_sc

aff_

426_

GE

NE

_6N

-ace

tylg

utam

ate

synt

hase

439

9292

29.5

10.8

67.

116

.26

232

2Le

ptoI

I_sc

aff_

426_

GE

NE

_7rib

osom

al p

rote

in S

2 (4

26-7

, 13-

68)

2310

7070

77.6

53.8

654

.157

.261

.22

Lept

oII_

scaf

f_42

8_G

EN

E_2

cons

erve

d hy

poth

etic

al29

6.2

2838

.79.

0611

.52

Lept

oII_

scaf

f_42

8_G

EN

E_3

uniq

ue h

ypot

hetic

al17

745

.638

.76

22

Lept

oII_

scaf

f_42

8_G

EN

E_6

uniq

ue h

ypot

hetic

al24

977

.767

.96

59.0

629

.26

54.7

29.6

22

Lept

oII_

scaf

f_42

8_G

EN

E_7

oute

r mem

bran

e ef

flux

prot

ein/

mul

tidru

g ef

flux

pum

p (4

28-7

, 71

109

1013

913

920

.14.

568

1.1

82

2Le

ptoI

I_sc

aff_

429_

GE

NE

_3rib

osom

al p

rote

in L

9 (4

29-3

, 150

-15)

179.

320

2061

.343

.144

.925

.13

52.2

61.3

22

Lept

oII_

scaf

f_42

9_G

EN

E_5

uniq

ue h

ypot

hetic

al (s

imila

r to

287-

6)30

5.7

9.5

4.5

22

Lept

oII_

scaf

f_43

_GE

NE

_10

alph

a-am

ylas

e 82

598

9822

.411

.16

12.5

3.4

22

Lept

oII_

scaf

f_43

_GE

NE

_11

gala

ctos

e-1-

phos

phat

e ur

idyl

yltra

nsfe

rase

395.

710

096

62.9

13.2

35.8

16.7

22

Lept

oII_

scaf

f_43

_GE

NE

_12

uniq

ue h

ypot

hetic

al (l

ike

fruct

ose

bisp

hosp

hate

ald

olas

e)52

68

857

.443

.142

.33

43.2

641

.32

2Le

ptoI

I_sc

aff_

43_G

EN

E_1

3co

nser

ved

hypo

thet

ical

616

127

17.6

8.6

8.56

22

Lept

oII_

scaf

f_43

_GE

NE

_14

efflu

x tra

nspo

rter

4110

3529

61.9

31.3

627

.644

.16

34.3

618

.92

2Le

ptoI

I_sc

aff_

43_G

EN

E_1

5ca

tion

efflu

x pr

otei

n 11

78

00

27.1

13.5

15.7

31.

962

2Le

ptoI

I_sc

aff_

43_G

EN

E_1

6gl

ycin

e cl

eava

ge s

yste

m; a

min

omet

hyltr

ansf

eras

e37

616

1458

.426

.03

36.5

32.3

324

.62

Lept

oII_

scaf

f_43

_GE

NE

_17

acet

oace

tate

met

abol

ism

regu

lato

r/res

pons

e re

gula

tor i

n tw

o-c

529.

288

8714

.51.

74.

236.

032

2Le

ptoI

I_sc

aff_

43_G

EN

E_1

8ef

flux

trans

porte

r46

1033

3350

.637

.233

.910

.83

27.9

315

.62

2Le

ptoI

I_sc

aff_

43_G

EN

E_1

9ef

flux

prot

ein

559

5649

39.4

28.3

32.3

61.

8326

.06

13.3

22

Lept

oII_

scaf

f_43

_GE

NE

_2ca

tion

efflu

x tra

nspo

rter

3110

2222

41.5

23.4

330

.23

27.6

314

.22

2Le

ptoI

I_sc

aff_

43_G

EN

E_2

0th

iore

doxi

n re

duct

ase

336

9595

42.9

15.0

634

.121

.617

.72

Lept

oII_

scaf

f_43

_GE

NE

_21

uniq

ue h

ypot

hetic

al18

5.7

9.4

3.13

22

Lept

oII_

scaf

f_43

_GE

NE

_22

uniq

ue h

ypot

hetic

al33

954

.939

.13

34.5

642

.736

.333

.92

Lept

oII_

scaf

f_43

_GE

NE

_23

thym

idyl

ate

kina

se78

5.7

013

615

.83.

0310

.43

2Le

ptoI

I_sc

aff_

43_G

EN

E_2

4ca

rbox

yles

tera

se

265.

238

3816

.18.

134.

065.

53

2Le

ptoI

I_sc

aff_

43_G

EN

E_2

6N

-form

ylm

ethi

onyl

-tRN

A d

efor

myl

ase

206.

526

2619

.86.

62

2Le

ptoI

I_sc

aff_

43_G

EN

E_2

7m

ethi

onyl

-tRN

A fo

rmyl

trans

fera

se

358

6161

32.6

10.7

62.

313

.46

7.63

2Le

ptoI

I_sc

aff_

43_G

EN

E_2

8pe

ptid

ase,

M48

fam

ily/s

mal

l hea

t sho

ck p

rote

in32

6.3

7978

32.2

13.1

315

.46

3.26

22

Lept

oII_

scaf

f_43

_GE

NE

_29

ribul

ose

phos

phat

e 3-

epim

eras

e25

659

5912

.16.

24.

032

Lept

oII_

scaf

f_43

_GE

NE

_30

uniq

ue h

ypot

hetic

al (4

3-30

, 277

-1)

169.

124

.84.

9310

.06

22

Lept

oII_

scaf

f_43

_GE

NE

_31

actin

-like

ATP

ase

(43-

31, 2

77-2

)31

699

9955

.839

.33

41.4

329

.36

30.9

22

Lept

oII_

scaf

f_43

_GE

NE

_4X

aa-P

ro d

ipep

tidas

e42

5.8

7676

37.5

11.8

313

.912

.66.

82

2Le

ptoI

I_sc

aff_

43_G

EN

E_5

O-m

ethy

ltran

sfer

ase

257

1410

54.5

43.8

30.1

35.

4646

.63

27.7

22

Lept

oII_

scaf

f_43

_GE

NE

_6as

sim

ilato

ry n

itrat

e re

duct

ase

116.

313

1331

.414

.710

.13

22.5

22.5

22

Lept

oII_

scaf

f_43

_GE

NE

_8gl

ucos

e-1-

phos

phat

e ad

enyl

yltra

nsfe

rase

47

611

911

945

.614

.526

.515

.511

.72

2Le

ptoI

I_sc

aff_

43_G

EN

E_9

amyl

opul

lula

nase

835.

412

587

20.1

7.8

7.1

1.96

22

Lept

oII_

scaf

f_43

5_G

EN

E_9

NA

DH

deh

ydro

gena

se I,

F s

ubun

it (4

35-9

, 14-

3, s

imila

r to

51- 5

386.

135

3434

.917

.319

.43

8.8

12.3

2Le

ptoI

I_sc

aff_

44_G

EN

E_1

3se

nsor

y bo

x/G

GD

EF

fam

ily p

rote

in16

35.

955

533.

91.

32

2Le

ptoI

I_sc

aff_

44_G

EN

E_1

5m

ulti-

drug

resi

stan

ce e

fflux

pum

p38

1028

2542

.915

.216

.23

20.6

62

2Le

ptoI

I_sc

aff_

44_G

EN

E_1

6ou

ter m

embr

ane

prot

ein

TolC

51

1012

1217

.711

.93

11.8

31.

762

2Le

ptoI

I_sc

aff_

44_G

EN

E_1

7m

alat

e de

hydr

ogen

ase

356

8181

53.1

28.9

643

.03

29.8

632

.52

2Le

ptoI

I_sc

aff_

44_G

EN

E_1

8un

ique

hyp

othe

tical

1710

11.3

3.76

2Le

ptoI

I_sc

aff_

44_G

EN

E_1

9un

ique

hyp

othe

tical

2410

79.

91.

733.

32

2Le

ptoI

I_sc

aff_

44_G

EN

E_2

0A

BC

tran

spor

ter

286

8482

194.

436.

313

.56

2Le

ptoI

I_sc

aff_

44_G

EN

E_2

1R

NA

pol

ymer

ase

sigm

a-54

fact

or

545.

187

8729

.415

.25.

92

2Le

ptoI

I_sc

aff_

44_G

EN

E_2

2rib

osom

al p

rote

in S

3020

830

3058

44.9

46.8

18.5

351

.16

52.3

22

Lept

oII_

scaf

f_44

_GE

NE

_24

uniq

ue h

ypot

hetic

al21

1021

.819

.33

15.9

3.63

8.26

11.4

22

Lept

oII_

scaf

f_44

_GE

NE

_25

chor

ism

ate

synt

hase

448

9797

36.4

8.46

15.6

315

.13

2Le

ptoI

I_sc

aff_

44_G

EN

E_2

6sh

ikim

ate

kina

se I

215.

726

2432

.23.

635.

14

22

Lept

oII_

scaf

f_44

_GE

NE

_27

3-de

hydr

oqui

nate

syn

thet

ase

395.

972

7228

.29.

667.

638.

12

2Le

ptoI

I_sc

aff_

44_G

EN

E_2

8si

gma

fact

or re

gula

tory

pro

tein

48

631

1843

.215

.13

32.2

311

.33

11.4

22

Lept

oII_

scaf

f_44

_GE

NE

_3R

ecA

pro

tein

398

123

123

63.1

38.9

638

.86

13.4

346

.444

.42

2Le

ptoI

I_sc

aff_

44_G

EN

E_3

2G

TP c

yclo

hydr

olas

e I

179

3518

48.3

5.13

12.7

624

.636

.46

24.2

22

Lept

oII_

scaf

f_44

_GE

NE

_4al

anyl

tRN

A s

ynth

etas

e10

06

00

44.8

13.5

24.9

37.

63.

82

2Le

ptoI

I_sc

aff_

44_G

EN

E_5

uniq

ue h

ypot

hetic

al10

951

.18.

529

.834

.76

36.2

2Le

ptoI

I_sc

aff_

44_G

EN

E_7

4-am

ino-

4-de

oxyc

horis

mat

e ly

ase

399.

547

3614

.714

.72

2Le

ptoI

I_sc

aff_

44_G

EN

E_8

valy

l tR

NA

syn

thet

ase

104

60

027

.111

.63

14.1

38.

466.

42

2Le

ptoI

I_sc

aff_

44_G

EN

E_9

nico

tinat

e-nu

cleo

tide

pyro

phos

phor

ylas

e32

653

5320

.96.

962.

962

Lept

oII_

scaf

f_44

0_G

EN

E_3

mat

ing

pair

form

atio

n pr

otei

n Tr

bB

359.

424

2414

.92.

332.

632

Lept

oII_

scaf

f_45

_GE

NE

_13

thym

idin

e ph

osph

oryl

ase

535.

50

1613

.74.

833.

732

2Le

ptoI

I_sc

aff_

45_G

EN

E_1

5co

nser

ved

hypo

thet

ical

2410

2548

.218

.36

24.7

43.9

333

.66

24.5

2Le

ptoI

I_sc

aff_

45_G

EN

E_3

0un

ique

hyp

othe

tical

95.

638

.312

.76

2Le

ptoI

I_sc

aff_

45_G

EN

E_3

3co

nser

ved

hypo

thet

ical

186

2118

.26.

062

Lept

oII_

scaf

f_45

_GE

NE

_35

plas

mid

sta

biliz

atio

n pr

otei

n 15

5.1

4848

26.4

16.6

62

2Le

ptoI

I_sc

aff_

45_G

EN

E_4

0co

nser

ved

hypo

thet

ical

215

3256

.46.

238

.12

Lept

oII_

scaf

f_45

_GE

NE

_41

two-

com

pone

nt re

spon

se re

gula

tor/H

D d

omai

n pr

otei

n29

5.9

2626

40.6

2.76

28.5

2Le

ptoI

I_sc

aff_

45_G

EN

E_4

6co

nser

ved

hypo

thet

ical

4110

1215

.85.

262

Lept

oII_

scaf

f_45

_GE

NE

_7co

nser

ved

hypo

thet

ical

209.

658

23.1

10.4

2Le

ptoI

I_sc

aff_

454_

GE

NE

_3co

nser

ved

hypo

thet

ical

378.

433

8.7

2.9

22

Lept

oII_

scaf

f_45

4_G

EN

E_6

met

hyl-a

ccep

ting

chem

otax

is tr

ansd

ucer

9

513

1140

.513

.534

.53

21.0

32

2Le

ptoI

I_sc

aff_

46_G

EN

E_1

uniq

ue h

ypot

hetic

al (4

6-1,

297

-4)

169.

544

.328

.212

.233

.640

.46

30.5

2Le

ptoI

I_sc

aff_

46_G

EN

E_1

0co

nser

ved

hypo

thet

ical

286

4737

9.23

20.6

9.66

22

Lept

oII_

scaf

f_46

_GE

NE

_11

gluc

ose-

6-ph

osph

ate

isom

eras

e 61

60

049

.621

.96

24.1

314

.53

22

Lept

oII_

scaf

f_46

_GE

NE

_12

LexA

repr

esso

r23

9.2

3636

28.8

15.6

22

Lept

oII_

scaf

f_46

_GE

NE

_16

cyto

chro

me

c28

1068

6867

.816

.611

.36

57.8

616

.616

.92

2Le

ptoI

I_sc

aff_

46_G

EN

E_1

7so

lubl

e cy

toch

rom

e cB

/cyt

ochr

ome

c553

249.

828

2157

.45.

0639

.76

40.0

624

.525

.62

2Le

ptoI

I_sc

aff_

46_G

EN

E_2

arse

nate

redu

ctas

e (4

6-2,

297

-2)

307

2828

73.2

34.3

339

.96.

9336

.56

52.8

2Le

ptoI

I_sc

aff_

46_G

EN

E_2

2un

ique

hyp

othe

tical

(46-

22, 4

2-29

, 944

-1)

398.

46

8.8

2.93

2Le

ptoI

I_sc

aff_

46_G

EN

E_2

3ca

rote

noid

isom

eras

e/ph

ytoe

ne d

ehyd

roge

nase

559.

542

326.

22.

062

Lept

oII_

scaf

f_46

_GE

NE

_24

uniq

ue h

ypot

hetic

al19

1219

.16.

362

Lept

oII_

scaf

f_46

_GE

NE

_27

di-h

eme

cyto

chro

me

c30

1066

634.

81.

62

Lept

oII_

scaf

f_46

_GE

NE

_28

di-h

eme

cyto

chro

me

c30

9.7

4844

26.4

8.8

22

Lept

oII_

scaf

f_46

_GE

NE

_4un

ique

hyp

othe

tical

119

6764

.435

.26

22

Lept

oII_

scaf

f_46

_GE

NE

_5un

ique

hyp

othe

tical

229

752

4235

.66

3239

29.5

22

Lept

oII_

scaf

f_46

_GE

NE

_6un

ique

hyp

othe

tical

238

551

.734

.43

35.8

337

.43

43.1

339

.8

22

Lept

oII_

scaf

f_46

_GE

NE

_7ca

tion

efflu

x pr

otei

n 11

39

00

26.5

11.2

68.

962

2Le

ptoI

I_sc

aff_

467_

GE

NE

_1tR

NA

-pse

udou

ridin

e sy

ntha

se B

349

4845

103.

332

Lept

oII_

scaf

f_46

7_G

EN

E_2

uniq

ue h

ypot

hetic

al (s

imila

r to

ribos

ome-

bind

ing

fact

or A

)15

6.8

735

.911

.96

22

Lept

oII_

scaf

f_46

7_G

EN

E_4

trans

latio

n in

itiat

ion

fact

or96

70

034

.713

.43

171.

313

.13

7.8

22

Lept

oII_

scaf

f_46

7_G

EN

E_5

N u

tiliz

atio

n su

bsta

nce

prot

ein

A53

592

9258

.540

.345

.45.

229

.823

.92

2Le

ptoI

I_sc

aff_

478_

GE

NE

_4m

obili

zatio

n pr

otei

n Tr

aI13

16

8989

7.3

1.36

0.73

3.1

22

Lept

oII_

scaf

f_47

8_G

EN

E_6

uniq

ue h

ypot

hetic

al (4

78-6

, 768

-4)

116

469

.149

.83

58.7

658

.76

48.5

22

Lept

oII_

scaf

f_48

_GE

NE

_1hi

ston

e8

1011

1185

.346

.23

62.2

369

.33

60.4

664

2Le

ptoI

I_sc

aff_

48_G

EN

E_1

0un

ique

hyp

othe

tical

165.

413

.513

.52

2Le

ptoI

I_sc

aff_

48_G

EN

E_1

1fe

rrid

oxin

oxi

dore

duct

ase

217

5653

50.8

36.6

34.2

347

36.8

22

Lept

oII_

scaf

f_48

_GE

NE

_12

uniq

ue h

ypot

hetic

al9

455

.314

.03

9.2

3227

.62

2Le

ptoI

I_sc

aff_

48_G

EN

E_1

3py

ruva

te fe

rrid

oxin

oxi

dore

duct

ase

gam

ma

subu

nit

205

5757

72.1

33.9

36.4

348

.06

32.2

22

Lept

oII_

scaf

f_48

_GE

NE

_14

pyru

vate

ferr

idox

in o

xido

redu

ctas

e be

ta s

ubun

it - t

runc

ated

139

2525

79.5

63.5

362

.423

.93

66.3

652

.12

2Le

ptoI

I_sc

aff_

48_G

EN

E_1

5fe

rrid

oxin

oxi

dore

duct

ase

166

3939

48.9

43.6

343

.63

46.2

647

.52

2Le

ptoI

I_sc

aff_

48_G

EN

E_1

6fe

rrid

oxin

oxi

dore

duct

ase

456

133

133

66.5

48.9

41.0

633

.334

.72

2Le

ptoI

I_sc

aff_

48_G

EN

E_1

7un

ique

hyp

othe

tical

108

4012

.96

12.9

330

.62

2Le

ptoI

I_sc

aff_

48_G

EN

E_1

8fe

rrid

oxin

11

611

1141

.626

.43

38.9

67.

635

33.7

22

Lept

oII_

scaf

f_48

_GE

NE

_19

pyru

vate

:ferr

idox

in o

xido

redu

ctas

e, g

amm

a 26

971

7192

.272

.458

.240

.490

.93

88.4

22

Lept

oII_

scaf

f_48

_GE

NE

_20

ferr

idox

in o

xido

redu

ctas

e32

910

810

876

.755

.36

565.

851

.83

38.5

22

Lept

oII_

scaf

f_48

_GE

NE

_21

ferr

idox

in o

xido

redu

ctas

e30

688

8861

.531

.626

.16

35.1

633

.72

2Le

ptoI

I_sc

aff_

48_G

EN

E_2

4un

ique

hyp

othe

tical

85

100

61.4

638

.170

.93

74.3

22

Lept

oII_

scaf

f_48

_GE

NE

_26

glut

amat

e-1-

sem

iald

ehyd

e am

inot

rans

fera

se

296

7474

37.2

13.1

627

.06

18.3

22

Lept

oII_

scaf

f_48

_GE

NE

_27

phos

phoh

epto

se is

omer

ase

226

4949

49.3

22.3

638

.63

24.3

322

.72

Lept

oII_

scaf

f_48

_GE

NE

_28

phos

phoh

epto

se is

omer

ase

208.

549

4918

.46.

132

Lept

oII_

scaf

f_48

_GE

NE

_29

trans

crip

tion-

repa

ir co

uplin

g fa

ctor

131

5.8

00

140.

764.

32

2Le

ptoI

I_sc

aff_

48_G

EN

E_3

Clp

pro

teas

e97

50

074

.446

.46

54.7

649

.440

.92

2Le

ptoI

I_sc

aff_

48_G

EN

E_3

0pe

ptid

yl-p

roly

l cis

-tran

s is

omer

ase

3210

2121

57.4

45.2

344

.63

4.83

37.8

346

.42

2Le

ptoI

I_sc

aff_

48_G

EN

E_3

1pa

rvul

in-li

ke p

eptid

yl-p

roly

l iso

mer

ase

3710

1615

24.4

7.4

4.93

5.56

14.8

22

Lept

oII_

scaf

f_48

_GE

NE

_32

pept

idyl

-pro

lyl c

is-tr

ans

isom

eras

e39

1032

3267

.425

27.8

358

.93

22.2

310

.92

Lept

oII_

scaf

f_48

_GE

NE

_33

GTP

-bin

ding

pro

tein

249.

825

2124

.15.

663

2.36

22

Lept

oII_

scaf

f_48

_GE

NE

_36

cons

erve

d hy

poth

etic

al41

633

186.

9312

3.36

7.3

22

Lept

oII_

scaf

f_48

_GE

NE

_5D

naJ

prot

ein

328

4136

31.7

3.16

4.33

24.2

615

.82

2Le

ptoI

I_sc

aff_

48_G

EN

E_6

L-as

parta

te o

xida

se

567

9595

19.9

4.86

6.7

2Le

ptoI

I_sc

aff_

48_G

EN

E_7

uniq

ue h

ypot

hetic

al17

9.3

39.2

21.3

610

.03

7.2

22

Lept

oII_

scaf

f_48

_GE

NE

_8gl

utam

yl-tR

NA

syn

thet

ase

546

147

141

29.3

12.8

618

.56

9.76

22

Lept

oII_

scaf

f_48

2_G

EN

E_1

actin

-like

ATP

ase

356

102

102

30.5

17.1

316

.12.

92

Lept

oII_

scaf

f_48

2_G

EN

E_7

ribon

ucle

ase

G

235.

347

474.

81.

62

Lept

oII_

scaf

f_48

3_G

EN

E_2

mer

curic

redu

ctas

e50

765

6525

.85.

8311

.33

3.7

9.3

2Le

ptoI

I_sc

aff_

483_

GE

NE

_3se

nsor

y bo

x pr

otei

n13

15.

798

861.

40.

462

Lept

oII_

scaf

f_49

0_G

EN

E_1

uniq

ue h

ypot

hetic

al27

5.1

34.4

7.13

9.56

22

Lept

oII_

scaf

f_49

0_G

EN

E_2

uniq

ue h

ypot

hetic

al8.

59.

246

.79.

769.

7633

.32

Lept

oII_

scaf

f_51

_GE

NE

_10

mul

tidru

g ef

flux

mem

bran

e fu

sion

pro

tein

Mex

F11

39.

10

04

1.93

22

Lept

oII_

scaf

f_51

_GE

NE

_13

Mar

R (m

ultip

le a

ntib

iotic

resi

stan

ce) t

rans

crip

tiona

l reg

ulat

or21

512

1172

.925

.228

.36

24.6

648

.83

23.8

22

Lept

oII_

scaf

f_51

_GE

NE

_14

Zn-d

epen

dant

alc

ohol

deh

ydro

gena

se35

696

9642

.515

.425

.33

15.9

62

Lept

oII_

scaf

f_51

_GE

NE

_15

exod

eoxy

ribon

ucle

ase

V, g

amm

a su

buni

t/Rec

C12

55.

881

816.

52.

30.

92

Lept

oII_

scaf

f_51

_GE

NE

_16

exod

eoxy

ribon

ucle

ase

V b

eta

chai

n12

46

7676

5.3

1.76

2Le

ptoI

I_sc

aff_

51_G

EN

E_1

7ex

odeo

xyrib

onuc

leas

e V

, alp

ha s

ubun

it63

6.6

6262

4.7

1.56

2Le

ptoI

I_sc

aff_

51_G

EN

E_2

4un

ique

hyp

othe

tical

(sim

ilar t

o iro

n(III

) dic

itrat

e tra

nspo

rt pr

otei

n10

55.

19

31

2Le

ptoI

I_sc

aff_

51_G

EN

E_6

sens

ory

hist

idin

e pr

otei

n ki

nase

/GG

DE

F do

mai

n pr

otei

n (5

1-6,

36

5.4

9797

7.1

2.36

22

Lept

oII_

scaf

f_51

1_G

EN

E_2

uniq

ue h

ypot

hetic

al (s

imila

r to

trans

-sia

lidas

e) (1

131-

3, 5

11-2

)33

107

482

.554

.829

.03

67.1

38.8

361

.22

Lept

oII_

scaf

f_51

1_G

EN

E_4

uniq

ue h

ypot

hetic

al55

5.6

49.

95.

40.

662

2Le

ptoI

I_sc

aff_

511_

GE

NE

_5un

ique

hyp

othe

tical

216

874

.654

.26

26.3

8.63

11.7

32

Lept

oII_

scaf

f_51

1_G

EN

E_8

gluc

okin

ase

375.

652

523.

51.

161.

162

Lept

oII_

scaf

f_52

6_G

EN

E_2

trans

posa

se-li

ke11

9.3

1010

15.6

5.2

22

Lept

oII_

scaf

f_52

6_G

EN

E_4

uniq

ue h

ypot

hetic

al (s

imila

r to

TDP

-glu

cose

-4,6

-deh

ydra

tase

) 34

86

517

.72.

910

.13

22

Lept

oII_

scaf

f_52

6_G

EN

E_5

dTD

P-4

-deh

ydro

rham

nose

3,5

-epi

mer

ase

226

6969

51.6

21.9

623

.934

.924

.52

2Le

ptoI

I_sc

aff_

526_

GE

NE

_6U

DP

-glu

cose

4-e

pim

eras

e 12

921

1241

.125

.630

.415

.22

2Le

ptoI

I_sc

aff_

526_

GE

NE

_7ep

imer

ase/

dehy

drat

ase

137

2828

52.2

19.1

312

.16

19.1

32

2Le

ptoI

I_sc

aff_

526_

GE

NE

_8al

pha-

D-g

luco

se-1

-pho

spha

te c

ytid

ylyl

trans

fera

se29

610

610

416

.39.

332

2Le

ptoI

I_sc

aff_

53_G

EN

E_1

ribos

omal

pro

tein

S18

(271

-12,

53-

1)9

1015

1561

.823

.26

37.3

39.0

643

.4

22

Lept

oII_

scaf

f_53

_GE

NE

_11

uniq

ue h

ypot

hetic

al47

1031

.623

.53

26.1

9.8

10.7

2Le

ptoI

I_sc

aff_

53_G

EN

E_1

2un

ique

hyp

othe

tical

2510

2416

.26

11.5

32.

932

2Le

ptoI

I_sc

aff_

53_G

EN

E_1

3cl

p pr

otea

se A

TP-b

indi

ng s

ubun

it C

lpX

44

514

714

752

.525

.06

35.5

614

.83

22

Lept

oII_

scaf

f_53

_GE

NE

_14

prot

ease

226

7676

45.8

24.6

320

.03

28.2

327

.62

2Le

ptoI

I_sc

aff_

53_G

EN

E_1

5un

ique

hyp

othe

tical

(lik

e pe

ptid

yl-p

roly

l cis

-tran

s is

omer

ase)

535

77

4130

.537

.632

.63

31.4

2Le

ptoI

I_sc

aff_

53_G

EN

E_1

6m

onoo

xyge

nase

, FA

D-b

indi

ng46

6.9

1716

8.9

4.16

2Le

ptoI

I_sc

aff_

53_G

EN

E_1

7un

ique

hyp

othe

tical

5911

7.4

6.26

3.8

1.36

22

Lept

oII_

scaf

f_53

_GE

NE

_18

gluc

ose

6-ph

osph

ate

dehy

drog

enas

e (s

imila

r to

191-

4)56

612

912

671

.737

.63

40.4

31.9

28.3

22

Lept

oII_

scaf

f_53

_GE

NE

_19

trans

aldo

lase

107

612

712

331

14.5

319

.43

14.3

69.

52

2Le

ptoI

I_sc

aff_

53_G

EN

E_2

sing

le-s

trand

DN

A b

indi

ng p

rote

in (5

3-2,

271

-13)

165.

321

2047

.914

.76

4.3

9.53

45.7

22

Lept

oII_

scaf

f_53

_GE

NE

_20

trans

keto

lase

746

00

30.1

18.1

616

.211

.713

.92

Lept

oII_

scaf

f_53

_GE

NE

_21

gluc

ose-

6-P

-deh

ydro

gena

se31

624

2012

82

Lept

oII_

scaf

f_53

_GE

NE

_22

gluc

okin

ase

385.

352

528.

12.

733.

862

2Le

ptoI

I_sc

aff_

53_G

EN

E_2

3un

ique

hyp

othe

tical

206

810

.39.

45.

062

2Le

ptoI

I_sc

aff_

53_G

EN

E_2

6un

ique

hyp

othe

tical

(dex

trans

ucra

se-li

ke) (

sim

ilar t

o 11

34-1

)48

107

711

.52.

135.

962

2Le

ptoI

I_sc

aff_

53_G

EN

E_3

uniq

ue h

ypot

hetic

al (l

ike

ribos

omal

pro

tein

S6)

(271

-14,

53-

3)14

8.7

88

45.9

33.6

25.1

322

.145

.63

37.7

22

Lept

oII_

scaf

f_53

_GE

NE

_4G

TP-b

indi

ng p

rote

in

405

117

117

54.7

31.2

31.9

630

.73

22.8

22

Lept

oII_

scaf

f_53

_GE

NE

_5pe

ptid

yl tR

NA

hyd

rola

se21

933

3232

.620

.16

18.9

26.9

22.8

38

22

Lept

oII_

scaf

f_53

_GE

NE

_6rib

osom

al p

rote

in L

2523

7.2

3030

60.4

43.3

52.6

649

.43

56.5

22

Lept

oII_

scaf

f_53

_GE

NE

_7rib

ose-

phos

phat

e py

roph

osph

okin

ase

348

102

102

73.9

32.4

662

.133

34.7

2Le

ptoI

I_sc

aff_

53_G

EN

E_8

isop

ente

nyl m

onop

hosp

hate

kin

ase

236.

226

2613

.14.

368.

732

2Le

ptoI

I_sc

aff_

569_

GE

NE

_2un

ique

hyp

othe

tical

265.

553

.65.

47.

5320

.13

2Le

ptoI

I_sc

aff_

57_G

EN

E_1

1G

TP c

yclo

hydr

olas

e I

216.

656

5619

.99.

233.

662

2Le

ptoI

I_sc

aff_

57_G

EN

E_1

2m

ethy

lene

tetra

hydr

ofol

ate

redu

ctas

e31

881

8179

.953

.16

56.2

36.

4671

.53

71.1

22

Lept

oII_

scaf

f_57

_GE

NE

_13

met

hyle

nete

trahy

drof

olat

e re

duct

ase

316

6362

31.5

10.6

312

.13

23.5

312

.82

2Le

ptoI

I_sc

aff_

57_G

EN

E_1

4ke

opan

toat

e hy

drox

ymet

hyltr

ansf

eras

e30

862

6123

.84.

8611

.26

22

Lept

oII_

scaf

f_57

_GE

NE

_15

catio

n tra

nspo

rt re

gula

tor

214.

814

1168

.542

41.4

335

.93

2Le

ptoI

I_sc

aff_

57_G

EN

E_1

7co

nser

ved

hypo

thet

ical

(sim

ilar t

o ac

yl-[A

CP

] des

atur

ases

)33

6.1

118

7.7

2.56

22

Lept

oII_

scaf

f_57

_GE

NE

_18

chem

otax

is re

cept

or -

Lept

o. fe

rroo

xida

ns41

6.4

3535

53.2

3125

.230

.73

16.9

2Le

ptoI

I_sc

aff_

57_G

EN

E_1

9gl

ycol

ate

oxid

ase

subu

nit G

lcD

104

6.8

111

694.

41.

130.

82

2Le

ptoI

I_sc

aff_

57_G

EN

E_2

cons

erve

d hy

poth

etic

al28

571

34.5

14.1

620

.23

20.3

311

.12

Lept

oII_

scaf

f_57

_GE

NE

_20

CM

P-b

indi

ng p

rote

in/H

D-h

ydro

lase

dom

ain

376.

346

3722

.68.

732

2Le

ptoI

I_sc

aff_

57_G

EN

E_2

1gl

utam

ate

synt

hase

[NA

DP

H] l

arge

cha

in

168

60

035

.512

.913

.93

7.9

22

Lept

oII_

scaf

f_57

_GE

NE

_22

cons

erve

d hy

poth

etic

al12

814

68.2

32.4

57.5

626

.06

47.5

652

.72

2Le

ptoI

I_sc

aff_

57_G

EN

E_2

3R

NA

pol

ymer

ase

566

5656

69.9

28.8

637

.63

1.53

37.3

32.5

22

Lept

oII_

scaf

f_57

_GE

NE

_24

acyl

phos

phat

ase

1110

1010

55.6

40.0

624

.26

45.5

22

Lept

oII_

scaf

f_57

_GE

NE

_26

fum

aras

e51

60

030

.610

.33

17.7

314

.220

22

Lept

oII_

scaf

f_57

_GE

NE

_3ch

oris

mat

e m

utas

e 41

798

9848

.516

.16

28.7

15.4

311

.52

2Le

ptoI

I_sc

aff_

57_G

EN

E_4

DA

HP

syn

thas

e in

aro

mat

ic a

min

o ac

id b

iosy

nthe

sis,

Aro

A37

610

710

080

.337

.43

47.3

33.

8350

49.4

2Le

ptoI

I_sc

aff_

57_G

EN

E_5

prep

hena

te d

ehyd

roge

nase

34

735

3230

.58.

1614

.99.

932

2Le

ptoI

I_sc

aff_

57_G

EN

E_6

5-en

olpy

ruvo

ylsh

ikim

ate-

3-ph

osph

ate

synt

hase

48

797

9310

.13.

31.

832

Lept

oII_

scaf

f_57

_GE

NE

_7cy

tidyl

ate

kina

se

256.

942

4115

.45.

1315

.42

Lept

oII_

scaf

f_57

_GE

NE

_81-

acyl

-sn-

glyc

erol

-3-p

hosp

hate

ace

tyltr

ansf

eras

e25

9.9

2622

314.

463.

38.

762

2Le

ptoI

I_sc

aff_

581_

GE

NE

_1un

ique

hyp

othe

tical

(581

-1, 6

2-1)

259

49.6

5.5

49.2

611

.73

12.6

22

Lept

oII_

scaf

f_58

1_G

EN

E_2

carb

onic

anh

ydra

se (s

imila

r to

147-

15, 3

-104

)12

6.8

4422

16.5

3.96

13.4

32

Lept

oII_

scaf

f_59

_GE

NE

_10

cons

erve

d hy

poth

etic

al (H

D-G

YP

hyd

rola

se d

omai

n)46

6.1

3328

8.53

6.86

9.9

22

Lept

oII_

scaf

f_59

_GE

NE

_11

anth

rani

late

syn

thas

e co

mpo

nent

II34

618

1457

.111

.86

1825

.16

17.1

22

Lept

oII_

scaf

f_59

_GE

NE

_12

tetra

pyrr

ole

met

hyla

se fa

mily

355

4040

56.1

16.8

11.3

27.9

317

.92

Lept

oII_

scaf

f_59

_GE

NE

_13

uniq

ue h

ypot

hetic

al5

8.3

26.7

8.9

22

Lept

oII_

scaf

f_59

_GE

NE

_14

sigm

a-54

dep

ende

nt D

NA

-bin

ding

resp

onse

regu

lato

r 51

761

5948

.310

.328

.53

15.3

2Le

ptoI

I_sc

aff_

59_G

EN

E_1

5cy

tosi

ne d

eam

inas

e18

6.5

3735

31.5

222

2Le

ptoI

I_sc

aff_

59_G

EN

E_1

6co

nser

ved

hypo

thet

ical

(TP

R re

peat

dom

ain

prot

ein)

388

1439

.737

.48.

52

2Le

ptoI

I_sc

aff_

59_G

EN

E_1

7po

tass

ium

effl

ux s

yste

m K

efA

33

740

2813

.73.

57

2.86

22

Lept

oII_

scaf

f_59

_GE

NE

_18

pept

ide

chai

n ra

leas

e fa

ctor

362

615

815

751

.28.

524

.38.

48.

52

2Le

ptoI

I_sc

aff_

59_G

EN

E_2

0co

nser

ved

hypo

thet

ical

115

1374

44.5

358

.03

65.0

663

.16

66.3

22

Lept

oII_

scaf

f_59

_GE

NE

_21

DN

A p

olym

eras

e III

, gam

ma

and

tau

subu

nits

626.

276

7640

.58.

3312

.83

5.5

22

Lept

oII_

scaf

f_59

_GE

NE

_22

uniq

ue h

ypot

hetic

al9

666

.330

.13

44.6

15.2

651

.82

2Le

ptoI

I_sc

aff_

59_G

EN

E_2

3un

ique

hyp

othe

tical

144

44.3

28.4

310

.66

40.2

322

Lept

oII_

scaf

f_59

_GE

NE

_24

uniq

ue h

ypot

hetic

al12

5.6

46.2

19.9

8.66

31.4

311

.52

Lept

oII_

scaf

f_59

_GE

NE

_26

uniq

ue h

ypot

hetic

al47

6.1

5.7

1.9

2Le

ptoI

I_sc

aff_

59_G

EN

E_2

7lip

opro

tein

28

9.9

2517

10.3

3.43

22

Lept

oII_

scaf

f_59

_GE

NE

_28

uniq

ue h

ypot

hetic

al20

1076

.870

.96

63.4

316

.23

55.5

45.9

22

Lept

oII_

scaf

f_59

_GE

NE

_29

oute

r mem

bran

e ef

flux

prot

ein

(4-1

, 59-

29)

528.

816

1354

.233

.83

31.4

625

.46

16.7

22

Lept

oII_

scaf

f_59

_GE

NE

_4lip

oam

ide

dehy

drog

enas

e of

2-o

xo a

cid

dehy

drog

enas

e (4

58-1

496

8888

34.3

14.2

68.

85.

82

Lept

oII_

scaf

f_59

_GE

NE

_5un

ique

hyp

othe

tical

535.

811

.45.

42

2Le

ptoI

I_sc

aff_

59_G

EN

E_6

acid

pho

spha

tase

379.

530

1646

.317

.111

.46

11.7

22

Lept

oII_

scaf

f_59

_GE

NE

_8co

nser

ved

hypo

thet

ical

145

1335

.421

.326

.922

.03

22

Lept

oII_

scaf

f_59

_GE

NE

_9co

nser

ved

hypo

thet

ical

(sim

ilar t

o m

olyb

dopt

erin

bio

synt

hesi

s M

97

165

8070

.475

63.8

74.6

802

2Le

ptoI

I_sc

aff_

6_G

EN

E_1

trans

posa

se30

637

2835

.58.

164.

4619

.73

22.9

212

2Le

ptoI

I_sc

aff_

6_G

EN

E_1

1A

BC

tran

spor

ter,

ATP

-bin

ding

pro

tein

, Msb

A fa

mily

66

912

011

15.

81.

51.

432

Lept

oII_

scaf

f_6_

GE

NE

_13

lipid

A d

isac

char

ide

synt

hase

458.

479

797.

92.

632

Lept

oII_

scaf

f_6_

GE

NE

_14

oxid

ored

ucta

se36

6.1

5856

26.5

10.8

2.6

2Le

ptoI

I_sc

aff_

6_G

EN

E_1

5ph

osph

atid

ate

cytid

yltra

nsfe

rase

33

6.2

5423

10.3

3.43

22

Lept

oII_

scaf

f_6_

GE

NE

_16

acet

yl tr

ansf

eras

e31

769

6935

.29.

8610

25.3

319

.52

2Le

ptoI

I_sc

aff_

6_G

EN

E_1

7U

DP

-3-O

-3-h

ydro

xym

yris

toyl

N-a

cety

lglu

cosa

min

e de

acet

ylas

e19

736

3641

.629

.86

27.5

626

.16

29.5

22

Lept

oII_

scaf

f_6_

GE

NE

_18

N-a

cety

ltran

sfer

ase

376

7272

45.4

33.9

631

.834

.63

36.9

22

Lept

oII_

scaf

f_6_

GE

NE

_19

uniq

ue h

ypot

hetic

al (l

ike

oute

r mem

bran

e pr

otei

n, O

mpH

)23

106

559

.542

36.3

358

.552

.33

422

2Le

ptoI

I_sc

aff_

6_G

EN

E_2

0ou

ter m

embr

ane

prot

ein

Om

p85

889

104

6743

.834

.13

25.5

314

.73

23.7

11.7

22

Lept

oII_

scaf

f_6_

GE

NE

_22

uniq

ue h

ypot

hetic

al (l

ike

isoc

itrat

e de

hydr

ogen

ase)

139

77

69.8

66.4

63.2

366

.469

.869

.82

2Le

ptoI

I_sc

aff_

6_G

EN

E_2

3is

ocitr

ate/

isop

ropy

lmal

ate

dehy

drog

enas

e37

6.7

9898

71.1

60.7

58.7

323

.93

62.1

55.4

22

Lept

oII_

scaf

f_6_

GE

NE

_24

prec

orrin

isom

eras

e37

644

4329

.314

.916

.723

.16

11.4

2Le

ptoI

I_sc

aff_

6_G

EN

E_2

5co

byrin

ic a

cid

506

7470

5.6

2.83

22

Lept

oII_

scaf

f_6_

GE

NE

_27

aldo

/ket

o re

duct

ase

386.

494

8770

.633

.46

32.9

637

.26

32.6

2Le

ptoI

I_sc

aff_

6_G

EN

E_3

5ni

cotin

ate-

nucl

eotid

e--d

imet

hylb

enzi

mid

azol

e ph

osph

orib

osyl

tr39

676

7621

.82.

417

.36

22

Lept

oII_

scaf

f_6_

GE

NE

_37

met

hyl c

hlor

ide

trans

fera

se23

5.7

3620

50.2

23.2

328

.36

22.9

2Le

ptoI

I_sc

aff_

6_G

EN

E_3

9un

ique

hyp

othe

tical

326.

39

9.1

3.03

22

Lept

oII_

scaf

f_6_

GE

NE

_40

heat

sho

ck p

rote

in d

naJ

409

8383

30.9

1216

.98.

139.

12

2Le

ptoI

I_sc

aff_

6_G

EN

E_4

1ch

aper

one

dnaK

695

00

76.6

66.6

667

.56

19.9

366

.965

.82

2Le

ptoI

I_sc

aff_

6_G

EN

E_4

2ch

aper

one

grpE

215

2121

68.3

24.7

25.7

657

.557

.12

2Le

ptoI

I_sc

aff_

6_G

EN

E_4

5ef

flux

trans

porte

r37

1055

5530

13.5

620

.03

127.

92

2Le

ptoI

I_sc

aff_

6_G

EN

E_4

6ef

flux

prot

ein

529

2824

43.3

31.1

626

.23

7.4

21.8

617

22

Lept

oII_

scaf

f_6_

GE

NE

_48

mul

ti-dr

ug re

sist

ance

effl

ux p

ump

337

3434

43.6

26.8

30.8

65.

433

29.1

2Le

ptoI

I_sc

aff_

6_G

EN

E_4

9co

nser

ved

hypo

thet

ical

(lik

e cy

toch

rom

e c-

554

prec

urso

r)22

7.2

105

13.5

4.5

2Le

ptoI

I_sc

aff_

6_G

EN

E_5

2un

ique

hyp

othe

tical

(sim

ilar t

o fo

rmat

e de

hydr

ogen

ase

form

ati o

356.

19

836

.13.

5314

.46

4.63

22

Lept

oII_

scaf

f_6_

GE

NE

_53

GTP

pyr

opho

spho

kina

se86

70

018

.41.

667.

73.

43.

062

Lept

oII_

scaf

f_6_

GE

NE

_54

sing

le s

trand

ed D

NA

-spe

cific

exo

nucl

ease

626.

149

4010

.23.

42

2Le

ptoI

I_sc

aff_

6_G

EN

E_5

6pr

otei

n-ex

port

mem

bran

e pr

otei

n S

ecF

3510

6767

22.7

4.66

6.13

22

Lept

oII_

scaf

f_6_

GE

NE

_57

prot

ein-

expo

rt m

embr

ane

prot

ein

Sec

D

579

135

135

2616

.96

17.2

315

.03

22

Lept

oII_

scaf

f_6_

GE

NE

_58

cons

erve

d hy

poth

etic

al10

1013

27.1

9.03

22

Lept

oII_

scaf

f_6_

GE

NE

_60

argi

nyl-t

RN

A s

ynth

etas

e 67

612

312

328

.912

.53

15.5

35.

062

Lept

oII_

scaf

f_6_

GE

NE

_61

O-s

ialo

glyc

opro

tein

end

opep

tidas

e 37

7.4

5959

7.5

2.33

1.43

22

Lept

oII_

scaf

f_6_

GE

NE

_62

Clp

C A

TPas

e 92

60

065

.726

.542

.13

15.6

15.3

2Le

ptoI

I_sc

aff_

6_G

EN

E_7

4is

oleu

cyl t

RN

A s

ynth

etas

e11

16.

40

017

.76.

268.

030.

461.

032

2Le

ptoI

I_sc

aff_

6_G

EN

E_7

6O

-link

ed G

lcN

Ac

trans

fera

se36

4.9

1413

28.9

17.1

315

.03

8.86

22

Lept

oII_

scaf

f_6_

GE

NE

_78

cons

erve

d hy

poth

etic

al49

861

6140

.46

44.6

637

.731

.52

Lept

oII_

scaf

f_6_

GE

NE

_79

octa

pren

yl-d

ipho

spha

te s

ynth

ase

365.

366

6422

.45.

266.

762

Lept

oII_

scaf

f_6_

GE

NE

_82

inos

itol-1

-mon

opho

spha

tase

30

553

5317

.311

.53

5.76

22

Lept

oII_

scaf

f_6_

GE

NE

_84

cons

erve

d hy

poth

etic

al60

611

051

.330

.66

27.0

311

.76

2Le

ptoI

I_sc

aff_

6_G

EN

E_8

7U

DP

-3-O

-[3-h

ydro

xym

yris

toyl

] N-a

cety

lglu

cosa

min

e de

acet

yla s

336.

353

534.

41.

462

2Le

ptoI

I_sc

aff_

6_G

EN

E_8

8un

ique

hyp

othe

tical

2310

2623

.16

21.4

4.1

16.7

22

Lept

oII_

scaf

f_62

_GE

NE

_1un

ique

hyp

othe

tical

(581

-1, 6

2-1)

269.

448

.95.

4348

.63

11.6

12.4

22

Lept

oII_

scaf

f_62

_GE

NE

_10

thio

ldis

ufid

e is

omer

ase,

thio

redo

xin

396.

735

2868

.465

.659

.53

62.9

363

.864

.22

2Le

ptoI

I_sc

aff_

62_G

EN

E_1

3un

ique

hyp

othe

tical

268

22.4

12.8

612

.12

2Le

ptoI

I_sc

aff_

62_G

EN

E_1

4un

ique

hyp

othe

tical

(thi

ored

oxin

-like

)25

68

830

.825

.321

.86

25.3

192

Lept

oII_

scaf

f_62

_GE

NE

_15

phos

phor

ibos

ylam

inoi

mid

azol

e ca

rbox

ylas

e, A

TPas

e su

buni

t42

6.1

9010

.53.

52.

162

2Le

ptoI

I_sc

aff_

62_G

EN

E_1

6ph

osph

orib

osyl

amin

oim

idiz

ol c

arbo

xyla

se18

946

4640

25.9

326

.26

32.2

29.1

22

Lept

oII_

scaf

f_62

_GE

NE

_17

NA

DP

-red

ucin

g hy

drog

enas

e, s

ubun

it C

496

9797

38.9

20.1

17.5

617

.63

18.1

2Le

ptoI

I_sc

aff_

62_G

EN

E_1

8un

ique

hyp

othe

tical

(sim

ilar t

o fe

rred

oxin

, 2Fe

-2S

)10

5.3

97

33.7

9.3

33.7

22

Lept

oII_

scaf

f_62

_GE

NE

_19

uniq

ue h

ypot

hetic

al29

105

4727

.03

34.8

616

.338

.76

34.5

2Le

ptoI

I_sc

aff_

62_G

EN

E_2

0tra

nsgl

ycos

ylas

e, S

lt fa

mily

4410

7675

28.1

15.5

37.

96

2Le

ptoI

I_sc

aff_

62_G

EN

E_2

1tra

nscr

iptio

nal r

egul

ator

, Crp

/Fnr

fam

ily27

5.4

2522

36.7

18.2

612

.82

Lept

oII_

scaf

f_62

_GE

NE

_25

cons

erve

d hy

poth

etic

al (s

imila

r to

acyl

-[AC

P] d

esat

uras

e)33

5.9

125

45.4

4.03

16.2

14.3

2Le

ptoI

I_sc

aff_

62_G

EN

E_2

7fe

rred

oxin

-nitr

ite re

duct

ase

626.

115

084

83.

432

Lept

oII_

scaf

f_62

_GE

NE

_3A

BC

tran

spor

ter A

TP-b

indi

ng p

rote

in29

720

187

4.66

22

Lept

oII_

scaf

f_62

_GE

NE

_4A

BC

tran

spor

ter,

perip

lasm

ic s

ubst

rate

-bin

ding

pro

tein

3410

1616

53.3

29.9

31.6

27.2

11.5

22

Lept

oII_

scaf

f_62

_GE

NE

_5un

ique

hyp

othe

tical

359

726

.219

.721

.53

1611

.52

Lept

oII_

scaf

f_62

_GE

NE

_7un

ique

hyp

othe

tical

2410

25.4

9.56

11.2

62

Lept

oII_

scaf

f_62

7_G

EN

E_1

man

nosy

ltran

sfer

ase

(627

-1, 7

3-4)

309.

448

4824

.38.

12

Lept

oII_

scaf

f_62

7_G

EN

E_2

glyc

osyl

tran

sfer

ase,

gro

up 1

(627

-2, 7

3-2,

73-

3)39

8.7

7979

9.7

3.23

2Le

ptoI

I_sc

aff_

627_

GE

NE

_5A

BC

tran

spor

ter A

TP-b

indi

ng p

rote

in15

9.3

3333

22.5

7.5

22

Lept

oII_

scaf

f_63

0_G

EN

E_3

uniq

ue h

ypot

hetic

al (s

imila

r to

865-

2)28

9.6

54.9

49.0

327

.237

.66

27.8

2Le

ptoI

I_sc

aff_

630_

GE

NE

_4tra

nspo

sase

467

123

114

8.8

2.93

22

Lept

oII_

scaf

f_63

0_G

EN

E_6

uniq

ue h

ypot

hetic

al (w

eak

sim

ilarit

y to

cyt

ochr

ome

c)60

535

.830

.46

28.6

627

.13

23.8

21.8

22

Lept

oII_

scaf

f_65

9_G

EN

E_1

glyc

osyl

trans

fera

se36

840

1032

.610

.13

4.16

8.9

2Le

ptoI

I_sc

aff_

659_

GE

NE

_3un

ique

hyp

othe

tical

218.

918

.56.

162

2Le

ptoI

I_sc

aff_

66_G

EN

E_1

thia

min

e bi

osyn

thes

is p

rote

in T

hiC

(134

-2, 6

6-1)

415

147

143

46.4

14.4

631

.96

16.3

611

.92

Lept

oII_

scaf

f_66

_GE

NE

_12

GTP

-bin

ding

pro

tein

Era

336.

549

478.

52.

832

2Le

ptoI

I_sc

aff_

66_G

EN

E_1

7D

P-m

anno

se p

yrop

hosp

hory

lase

566.

210

610

69.

64.

21.

032.

232

2Le

ptoI

I_sc

aff_

66_G

EN

E_1

8ph

osph

oman

nom

utas

e52

6.7

112

111

28.3

8.4

11.7

64.

92

2Le

ptoI

I_sc

aff_

66_G

EN

E_1

9fla

vohe

mog

lobi

n15

6.9

2718

27.1

14.5

318

.82

2Le

ptoI

I_sc

aff_

66_G

EN

E_2

0un

ique

hyp

othe

tical

79

754

.735

.96

29.7

39.1

22

Lept

oII_

scaf

f_66

_GE

NE

_21

uniq

ue h

ypot

hetic

al (l

ike

Fe/P

b pe

rmea

se, c

ytoc

hrom

e c)

13

99

946

.733

.325

.26

45.3

33.3

2Le

ptoI

I_sc

aff_

66_G

EN

E_2

2na

phth

alen

e-1,

2-di

oxyg

enas

e re

duct

ase

275.

716

1321

4.03

11.3

2Le

ptoI

I_sc

aff_

66_G

EN

E_2

4co

nser

ved

hypo

thet

ical

188.

433

17.8

2.36

11.8

62

Lept

oII_

scaf

f_66

_GE

NE

_27

long

-cha

in-fa

tty-a

cid

CoA

liga

se10

06.

994

948.

43.

734.

460.

862

Lept

oII_

scaf

f_66

_GE

NE

_28

clea

vage

and

pol

yade

nyla

tion

spec

ifici

ty fa

ctor

537.

491

855.

82.

562

2Le

ptoI

I_sc

aff_

66_G

EN

E_3

cons

erve

d hy

poth

etic

al (c

obal

amin

-bin

ding

dom

ain)

275

1236

.78.

5619

.96

22

Lept

oII_

scaf

f_66

_GE

NE

_4m

ethi

onin

e sy

ntha

se I,

cob

alam

in-b

indi

ng d

omai

n 88

50

171

43.6

14.3

322

.83

11.1

62

Lept

oII_

scaf

f_66

_GE

NE

_5m

etal

-dep

ende

nt h

ydro

lase

296

8840

378.

7613

.18.

98

22

Lept

oII_

scaf

f_66

_GE

NE

_6pe

ptid

yl-p

roly

l cis

-tran

s is

omer

ase

246

5454

32.6

4.9

7.2

27.2

328

28.4

22

Lept

oII_

scaf

f_66

_GE

NE

_7G

TP-b

indi

ng p

rote

in

695

00

57.5

18.8

635

.73

19.2

319

.32

Lept

oII_

scaf

f_66

_GE

NE

_8S

AM

-dep

ende

nt m

ethy

ltran

sfer

ase

448.

571

405.

13.

42

Lept

oII_

scaf

f_66

_GE

NE

_9co

nser

ved

hypo

thet

ical

375

1112

122

2Le

ptoI

I_sc

aff_

67_G

EN

E_1

uniq

ue h

ypot

hetic

al (6

7-1,

62-

28)

214

47.

27.

27.

22.

42

2Le

ptoI

I_sc

aff_

67_G

EN

E_1

63-

hydr

oxya

cid

dehy

drog

enas

e 32

743

3526

8.46

8.1

13.2

38.

22

Lept

oII_

scaf

f_67

_GE

NE

_17

AB

C tr

ansp

orte

r, A

TP-b

indi

ng p

rote

in27

7.1

5050

20.7

3.6

8.73

22

Lept

oII_

scaf

f_67

_GE

NE

_23

uniq

ue h

ypot

hetic

al (l

ike

met

hyl-a

ccep

ting

chem

otax

is p

rote

in)

549

77

20.5

11.9

610

.93

2.46

2Le

ptoI

I_sc

aff_

67_G

EN

E_2

4pr

olip

opro

tein

dia

cylg

lyce

ryl t

rans

fera

se

309.

569

698.

82.

932

2Le

ptoI

I_sc

aff_

67_G

EN

E_2

5co

nser

ved

hypo

thet

ical

(sim

ilar t

o dn

aK d

elet

ion

supp

ress

or p

r16

513

774

.332

.83

25.7

38.5

74.3

22

Lept

oII_

scaf

f_67

_GE

NE

_27

NA

DH

deh

ydro

gena

se, s

ubun

it F

115

5.7

163

163

5729

35.4

21.8

11.2

2Le

ptoI

I_sc

aff_

67_G

EN

E_3

site

-spe

cific

reco

mbi

nase

369.

854

547.

65.

062

2Le

ptoI

I_sc

aff_

68_G

EN

E_1

0Is

pD/is

pF b

ifunc

tiona

l enz

yme

456

6862

140.

967.

569.

136.

12

2Le

ptoI

I_sc

aff_

68_G

EN

E_1

1pi

li re

tract

ion

prot

ein

PilT

388.

969

6531

.115

.414

.26

12.8

9.7

2Le

ptoI

I_sc

aff_

68_G

EN

E_1

5ad

enos

ylm

ethi

onin

e--8

-am

ino-

7-ox

onon

anoa

te a

min

otra

nsfe

r a52

6.4

9999

8.1

2.7

22

Lept

oII_

scaf

f_68

_GE

NE

_16

uniq

ue h

ypot

hetic

al32

1059

.932

.536

.66

35.0

638

.73

36.3

2Le

ptoI

I_sc

aff_

68_G

EN

E_1

8un

ique

hyp

othe

tical

115.

16

34.7

4.56

4.56

23.1

32

Lept

oII_

scaf

f_68

_GE

NE

_19

glyc

osyl

tran

sfer

ase

449.

626

1815

.48.

732

2Le

ptoI

I_sc

aff_

68_G

EN

E_2

phos

phor

ibos

ylam

ine-

glyc

ine

ligas

e 45

676

7620

.52.

032.

2611

.13

7.5

22

Lept

oII_

scaf

f_68

_GE

NE

_3ph

osph

orib

osyl

amin

oim

idaz

olec

arbo

xam

ide

form

yltra

nsfe

rase

566

151

150

48.5

2934

.533

.426

.22

Lept

oII_

scaf

f_68

_GE

NE

_4gl

ycos

yltra

nsfe

rase

579.

954

331.

80.

62

Lept

oII_

scaf

f_68

_GE

NE

_5gl

ycos

yltra

nsfe

rase

309.

342

397.

44.

932

Lept

oII_

scaf

f_68

_GE

NE

_6A

DP

-hep

tose

-LP

S h

epto

syltr

ansf

eras

e II

458.

144

1228

.55.

214

.76

4.23

2Le

ptoI

I_sc

aff_

68_G

EN

E_9

serin

e O

-ace

tyltr

ansf

eras

e26

9.5

6262

25.8

10.1

65.

932

2Le

ptoI

I_sc

aff_

682_

GE

NE

_5he

me

d1 b

iosy

nthe

sis

prot

ein

NirJ

/pre

dict

ed F

e-S

oxi

dore

duct

a39

7.5

141

1417

.515

.16

5.16

2Le

ptoI

I_sc

aff_

682_

GE

NE

_6al

coho

l deh

ydro

gena

se, z

inc-

cont

aini

ng (6

82-6

, 283

-3)

77.

917

1217

.111

.45.

72

Lept

oII_

scaf

f_68

4_G

EN

E_3

cons

erve

d hy

poth

etic

al27

8.8

2822

.72.

5315

.12

2Le

ptoI

I_sc

aff_

684_

GE

NE

_6co

nser

ved

hypo

thet

ical

206

2348

.39.

5316

.26

19.1

2Le

ptoI

I_sc

aff_

689_

GE

NE

_3cy

toch

rom

e c-

551

129.

217

148.

32.

762

Lept

oII_

scaf

f_69

_GE

NE

_6D

eaD

/Dea

H b

ox h

elic

ase

119

6.1

013

2.2

0.73

2Le

ptoI

I_sc

aff_

7_G

EN

E_1

1nu

cleo

tide

suga

r epi

mer

ase

386.

511

911

58.

22.

732.

73

22

Lept

oII_

scaf

f_7_

GE

NE

_12

UD

P-g

alac

topy

rano

se m

utas

e 42

713

613

647

.114

.619

.16

14.7

313

.12

Lept

oII_

scaf

f_7_

GE

NE

_26

ATP

ase

749

2215

153.

55.

71.

732

2Le

ptoI

I_sc

aff_

7_G

EN

E_2

8po

lysa

ccha

ride

trans

port

3210

2828

49.5

34.2

330

.26

15.5

328

.06

23.9

2Le

ptoI

I_sc

aff_

7_G

EN

E_3

4gl

ycos

yltra

nsfe

rase

419

3531

82.

662

Lept

oII_

scaf

f_7_

GE

NE

_4si

gma-

54 d

epen

dent

DN

A-b

indi

ng re

spon

se re

gula

tor

539

7676

12.6

4.23

22

Lept

oII_

scaf

f_7_

GE

NE

_41

UTP

-glu

cose

-1-p

hosp

hate

urid

ylyl

trans

fera

se

346

9393

51.8

10.2

13.5

622

.72

Lept

oII_

scaf

f_7_

GE

NE

_44

sigm

a-54

dep

ende

nt D

NA

-bin

ding

resp

onse

regu

lato

r53

6.6

102

102

5.7

3.23

2Le

ptoI

I_sc

aff_

7_G

EN

E_4

5un

ique

hyp

othe

tical

777.

83.

41.

132

Lept

oII_

scaf

f_7_

GE

NE

_46

cons

erve

d hy

poth

etic

al71

9.2

152.

42.

42

2Le

ptoI

I_sc

aff_

7_G

EN

E_5

UD

P-g

luco

se 4

-epi

mer

ase

357

8585

64.6

25.1

30.8

23.2

11.1

22

Lept

oII_

scaf

f_7_

GE

NE

_56

cons

erve

d hy

poth

etic

al11

99

2335

20.2

619

.86

9.1

19.7

620

2Le

ptoI

I_sc

aff_

7_G

EN

E_6

1re

spon

se re

gula

tor

425.

694

8414

.12.

738.

162.

42

Lept

oII_

scaf

f_7_

GE

NE

_62

Sen

sory

/regu

lato

ry p

rote

in rp

fC52

6.7

7171

5.5

1.83

22

Lept

oII_

scaf

f_7_

GE

NE

_7U

DP

-N-a

cety

l-D-m

anno

sam

inur

onat

e de

hydr

ogen

ase

486

132

125

61.2

28.3

337

.426

.23

18.2

2Le

ptoI

I_sc

aff_

7_G

EN

E_8

gluc

osam

ine-

fruct

ose-

6-ph

osph

ate

amin

otra

nsfe

rase

665.

613

112

88.

13.

22

Lept

oII_

scaf

f_7_

GE

NE

_9si

gma5

4-de

pend

ant t

rans

crip

tiona

l reg

ulat

or58

5.9

6969

19.1

4.9

2.2

3.73

2Le

ptoI

I_sc

aff_

71_G

EN

E_1

acrif

lavi

n re

sist

ance

pro

tein

(71-

1, 4

28-7

)35

1032

3216

.42.

636.

832

2Le

ptoI

I_sc

aff_

71_G

EN

E_1

0th

iore

doxi

n10

9.5

1816

89.2

9.23

25.7

24.1

69.0

689

.22

Lept

oII_

scaf

f_71

_GE

NE

_11

cyto

chro

me

b-c

com

plex

, cyt

ochr

ome

b su

buni

t 51

9.1

4340

2.6

0.86

22

Lept

oII_

scaf

f_71

_GE

NE

_12

cyto

chro

me

b/b6

com

plex

, iro

n-su

lfur s

ubun

it39

610

19.1

2.8

12.8

62

2Le

ptoI

I_sc

aff_

71_G

EN

E_1

3en

oyl a

cyl c

arrie

r pro

tein

286

6262

49.1

30.0

626

.927

.93

2Le

ptoI

I_sc

aff_

71_G

EN

E_1

4un

ique

hyp

othe

tical

439.

44.

93.

262

Lept

oII_

scaf

f_71

_GE

NE

_15

uniq

ue h

ypot

hetic

al43

418

.611

.43

2Le

ptoI

I_sc

aff_

71_G

EN

E_1

6D

NA

mis

mat

ch re

pair

prot

ein

mut

S91

5.7

143

143

4.4

1.9

2Le

ptoI

I_sc

aff_

71_G

EN

E_1

8ur

acil-

DN

A g

lyco

syla

se29

7.8

5151

3.4

1.13

2Le

ptoI

I_sc

aff_

71_G

EN

E_1

9un

ique

hyp

othe

tical

556.

114

.58.

662.

23.

832

2Le

ptoI

I_sc

aff_

71_G

EN

E_2

uniq

ue h

ypot

hetic

al19

66

53.6

34.3

320

.918

.26

2Le

ptoI

I_sc

aff_

71_G

EN

E_2

0ho

lo-(

acyl

-car

rier-

prot

ein)

syn

thas

e15

9.2

1817

48.9

12.0

34.

7622

.06

22

Lept

oII_

scaf

f_71

_GE

NE

_21

pyrid

oxal

pho

spha

te b

iosy

nthe

tic p

rote

in28

5.9

5351

33.3

9.93

19.2

14.6

22

Lept

oII_

scaf

f_71

_GE

NE

_22

zinc

pro

teas

e 46

579

7931

.612

.56

16.2

315

.515

.32

2Le

ptoI

I_sc

aff_

71_G

EN

E_2

4nu

cleo

tidyl

trans

fera

se78

60

063

.344

.647

.71.

431

.96

24.4

22

Lept

oII_

scaf

f_71

_GE

NE

_25

ribos

omal

pro

tein

S15

1011

1818

70.8

52.0

649

.416

.46

53.9

370

.82

Lept

oII_

scaf

f_71

_GE

NE

_4co

nser

ved

hypo

thet

ical

676

105.

52.

531.

062

2Le

ptoI

I_sc

aff_

71_G

EN

E_5

exop

olyp

hosp

hata

se34

5.9

3937

33.3

6.96

15.8

611

.53

8.9

2Le

ptoI

I_sc

aff_

71_G

EN

E_6

uniq

ue h

ypot

hetic

al14

5.2

217

2Le

ptoI

I_sc

aff_

71_G

EN

E_8

trans

latio

nal i

nhib

itor

135

2524

16.5

112

2Le

ptoI

I_sc

aff_

710_

GE

NE

_7un

ique

hyp

othe

tical

(sim

ilar t

o su

lfur t

rans

fer p

rote

in in

thia

min

e8

4.7

858

.613

.33

58.6

58.6

22

Lept

oII_

scaf

f_71

3_G

EN

E_1

GTP

ase

EF-

Tu (1

37-1

, 713

-1, s

imila

r to

527-

1, 2

71-1

)44

5.8

00

90.7

76.6

673

.215

.06

71.5

74.4

22

Lept

oII_

scaf

f_71

3_G

EN

E_2

elon

gatio

n fa

ctor

EF-

G77

50

076

.352

64.3

355

.751

22

Lept

oII_

scaf

f_71

3_G

EN

E_3

ribos

omal

pro

tein

S7

1010

2929

92.9

39.3

57.5

315

.06

72.6

376

.22

2Le

ptoI

I_sc

aff_

713_

GE

NE

_4rib

osom

al p

rote

in S

127

1125

2557

.417

.13

43.6

630

.86

57.4

57.4

22

Lept

oII_

scaf

f_71

7_G

EN

E_3

uniq

ue h

ypot

hetic

al (2

-89,

717

-3)

228.

942

.724

.616

.56

27.4

329

32.7

2Le

ptoI

I_sc

aff_

728_

GE

NE

_6un

ique

hyp

othe

tical

(sim

ilar t

o th

iol:d

isul

fide

inte

rcha

nge

prot

ei33

8.8

95.

71.

92

Lept

oII_

scaf

f_73

_GE

NE

_13

plas

mid

mai

nten

ance

sys

tem

kill

er p

rote

in11

9.8

2723

36.6

36.6

22

Lept

oII_

scaf

f_73

_GE

NE

_25

cons

erve

d hy

poth

etic

al18

511

37.6

17.8

318

.97.

8615

.73

22

Lept

oII_

scaf

f_73

_GE

NE

_26

cons

erve

d hy

poth

etic

al (h

ydro

lase

-like

)29

612

650

.45.

9633

.46

33.3

22

Lept

oII_

scaf

f_73

_GE

NE

_27

oxid

ored

ucta

se/ta

rtron

ic s

emia

ldeh

yde

redu

ctas

e33

529

2950

.517

.03

36.5

62.

362

2Le

ptoI

I_sc

aff_

73_G

EN

E_2

9un

ique

hyp

othe

tical

(Sec

A-li

ke)

565

846

.45.

5627

.76

2Le

ptoI

I_sc

aff_

73_G

EN

E_3

3re

vers

e tra

nscr

ipta

se43

1011

911

53.

71.

232

2Le

ptoI

I_sc

aff_

73_G

EN

E_3

5tra

nspo

sase

(191

-7, 7

3-35

, 374

-3)

178.

933

2973

.326

.26

12.5

65.

2644

.344

.52

2Le

ptoI

I_sc

aff_

73_G

EN

E_3

8tra

nspo

sase

-like

(73-

38, 1

73-1

6, 4

12-2

, 265

-10,

261

-9)

255.

438

3871

.434

.13

30.2

54.4

337

.12

Lept

oII_

scaf

f_73

_GE

NE

_4m

anno

syltr

ansf

eras

e (6

27-1

, 73-

4)40

9.3

5959

18.2

6.06

2Le

ptoI

I_sc

aff_

73_G

EN

E_5

(sim

ilar t

o 73

-15)

tran

spos

ase

385.

226

2518

.83.

765.

762

2Le

ptoI

I_sc

aff_

75_G

EN

E_1

5m

ethy

l-acc

eptin

g ch

emot

axis

pro

tein

267

1514

14.7

4.9

9.1

2Le

ptoI

I_sc

aff_

75_G

EN

E_4

DN

A h

elic

ase

161

5.9

117

100

2.2

1.2

2Le

ptoI

I_sc

aff_

759_

GE

NE

_1A

TP-d

epen

dent

pro

teas

e La

446.

229

143.

51.

162

2Le

ptoI

I_sc

aff_

76_G

EN

E_1

hypo

xant

hine

-gua

nine

pho

spho

ribos

yltra

nsfe

rase

198

3838

49.4

26.1

68.

934

.06

31.8

2Le

ptoI

I_sc

aff_

76_G

EN

E_1

0L-

lysi

ne 2

,3-a

min

omut

ase

425.

410

710

217

6.63

2.43

22

Lept

oII_

scaf

f_76

_GE

NE

_11

nitro

redu

ctas

e29

659

5238

.615

20.9

16.3

620

.12

Lept

oII_

scaf

f_76

_GE

NE

_12

2'-d

eoxy

cytid

ine

5'-tr

ipho

spha

te d

eam

inas

e41

5.9

7372

122.

562.

261.

73

22

Lept

oII_

scaf

f_76

_GE

NE

_13

AA

A A

TPas

e62

5.5

7976

19.4

6.83

146.

832

Lept

oII_

scaf

f_76

_GE

NE

_14

cons

erve

d hy

poth

etic

al58

577

23.8

1.46

3.96

3.3

2Le

ptoI

I_sc

aff_

76_G

EN

E_1

6pr

otea

som

e be

ta s

ubun

it 29

5.9

3333

18.9

6.3

4.8

4.53

2Le

ptoI

I_sc

aff_

76_G

EN

E_1

7un

ique

hyp

othe

tical

(sim

ilar t

o 20

S p

rote

asom

e al

pha-

subu

nit)

285.

59

934

.312

.63

11.8

39.

22

Lept

oII_

scaf

f_76

_GE

NE

_18

cons

erve

d hy

poth

etic

al55

564

37.2

8.16

11.8

62

2Le

ptoI

I_sc

aff_

76_G

EN

E_1

9di

hydr

ooro

tase

deh

ydro

gena

se41

672

7245

.724

.63

29.3

65.

4336

.06

17.4

22

Lept

oII_

scaf

f_76

_GE

NE

_20

hom

oser

ine

kina

se35

5.3

3332

237.

266.

1613

.87.

62

Lept

oII_

scaf

f_76

_GE

NE

_21

ferr

edox

in, 2

Fe-2

S13

6.8

1816

42.9

10.7

25.9

22

Lept

oII_

scaf

f_76

_GE

NE

_3rib

ofla

vin

kina

se /

FAD

syn

thas

e rib

C36

7.1

5252

264.

36.

92

2Le

ptoI

I_sc

aff_

76_G

EN

E_4

delta

-am

inol

evul

inic

aci

d de

hydr

atas

e36

5.6

106

103

24.8

4.06

12.2

64.

462

Lept

oII_

scaf

f_76

_GE

NE

_5ur

opor

phyr

inog

en-II

I c-m

ethy

ltran

sfer

ase

587

9494

15.6

8.06

2.33

11.1

9.9

22

Lept

oII_

scaf

f_76

_GE

NE

_6po

rpho

bilin

ogen

dea

min

ase

346.

771

6933

.82.

0320

.73

5.63

2Le

ptoI

I_sc

aff_

76_G

EN

E_7

glut

amyl

-tRN

A re

duct

ase

516.

277

768.

62.

32.

132

Lept

oII_

scaf

f_79

1_G

EN

E_1

oute

r mem

bran

e ef

flux

prot

ein

(sim

ilar t

o 81

-19)

515.

923

231.

60.

532

2Le

ptoI

I_sc

aff_

8_G

EN

E_1

uniq

ue h

ypot

hetic

al (p

utat

ive

lytic

enz

yme,

pep

tidog

lyca

n bi

ndi

1311

384

.330

.73

41.7

344

.633

.86

33.1

22

Lept

oII_

scaf

f_8_

GE

NE

_10

trans

latio

n in

itiat

ion

fact

or38

699

9966

.636

.86

38.6

643

.73

37.7

22

Lept

oII_

scaf

f_8_

GE

NE

_17

SA

M-d

epen

dant

met

hyltr

ansf

eras

e21

519

1854

.134

.43

39.3

345

.86

42.6

2Le

ptoI

I_sc

aff_

8_G

EN

E_1

8un

ique

hyp

othe

tical

249.

713

.98

22

Lept

oII_

scaf

f_8_

GE

NE

_20

uniq

ue h

ypot

hetic

al8

552

.152

.132

.86

2Le

ptoI

I_sc

aff_

8_G

EN

E_2

2am

inot

rans

fera

se45

8.5

132

132

51.1

9.93

20.1

33.

269

22

Lept

oII_

scaf

f_8_

GE

NE

_23

uniq

ue h

ypot

hetic

al24

953

2212

.86

48.0

626

.03

22

Lept

oII_

scaf

f_8_

GE

NE

_24

hom

oser

ine

dehy

drog

enas

e 48

611

411

145

.113

.03

21.2

310

.93

4.7

22

Lept

oII_

scaf

f_8_

GE

NE

_25

thre

onin

e sy

ntha

se38

811

011

056

.736

.73

39.1

624

.33

39.9

22

Lept

oII_

scaf

f_8_

GE

NE

_27

aspa

rtate

kin

ase

446

116

115

39.3

15.4

326

.36

19.2

37.

82

Lept

oII_

scaf

f_8_

GE

NE

_28

2-is

opro

pylm

alat

e sy

ntha

se60

5.8

168

168

11.9

7.36

7.43

22

Lept

oII_

scaf

f_8_

GE

NE

_3pa

ntet

hein

e-ph

osph

ate

aden

ylyl

trans

fera

se19

643

4162

19.3

39.9

310

.86

22

Lept

oII_

scaf

f_8_

GE

NE

_30

inte

grat

ion

host

fact

or H

imA

/his

tone

-like

1110

1212

85.7

44.2

48.6

330

.63

52.0

371

.42

Lept

oII_

scaf

f_8_

GE

NE

_31

uniq

ue h

ypot

hetic

al9

5.8

12.7

4.23

22

Lept

oII_

scaf

f_8_

GE

NE

_32

acid

pho

spha

tase

295.

456

5625

.65.

2617

.72

Lept

oII_

scaf

f_8_

GE

NE

_33

uniq

ue h

ypot

hetic

al21

5.3

9.5

3.16

22

Lept

oII_

scaf

f_8_

GE

NE

_34

cyst

einy

l-tR

NA

syn

thet

ase

556

110

107

16.3

5.16

12.3

64.

432

Lept

oII_

scaf

f_8_

GE

NE

_35

rRN

A m

ethy

lase

197.

732

2914

.44.

82

2Le

ptoI

I_sc

aff_

8_G

EN

E_3

6th

iol d

isul

fide

isom

eras

e27

920

2022

.617

.86

22

Lept

oII_

scaf

f_8_

GE

NE

_37

NH

(3)-

depe

nden

t NA

D(+

) syn

thet

ase

675

163

156

30.9

1516

.212

.914

.42

2Le

ptoI

I_sc

aff_

8_G

EN

E_3

8G

TP c

yclo

hydr

olas

e II

446

145

145

44.8

24.1

619

.06

10.2

624

.52

2Le

ptoI

I_sc

aff_

8_G

EN

E_3

9rib

ofla

vin

synt

hase

175

2929

37.9

14.3

34.1

632

.529

.82

2Le

ptoI

I_sc

aff_

8_G

EN

E_4

aspa

rtate

am

inot

rans

fera

se44

711

011

062

25.8

638

.03

25.4

13.2

2Le

ptoI

I_sc

aff_

8_G

EN

E_4

2ad

enyl

osuc

cina

te ly

ase

506.

111

411

420

.85.

814

.73

3.8

22

Lept

oII_

scaf

f_8_

GE

NE

_43

phos

phor

ibos

yl a

min

oida

zole

suc

cino

carb

oxam

ide

synt

heta

se27

665

6440

.617

12.4

19.8

13.4

2Le

ptoI

I_sc

aff_

8_G

EN

E_4

5un

ique

hyp

othe

tical

507.

221

.512

.56

5.23

2.46

7.8

2Le

ptoI

I_sc

aff_

8_G

EN

E_4

7ac

etat

e ki

nase

416.

171

707.

52.

52

Lept

oII_

scaf

f_8_

GE

NE

_56

Hly

D fa

mily

sec

retio

n pr

otei

n 34

1059

3828

.23

13.0

612

22

Lept

oII_

scaf

f_8_

GE

NE

_57

oute

r mem

bran

e ef

flux

prot

ein

487

1717

33.9

25.5

616

.46

11.3

22

Lept

oII_

scaf

f_8_

GE

NE

_58

cyto

chro

me

c-55

112

1014

1442

.732

.43

9.1

2Le

ptoI

I_sc

aff_

8_G

EN

E_5

9ph

osph

oket

olas

e89

6.4

00

26.5

10.2

613

.46

1.6

22

Lept

oII_

scaf

f_8_

GE

NE

_6un

ique

hyp

othe

tical

118

839

.612

.26

17.6

35.2

39.6

22

Lept

oII_

scaf

f_8_

GE

NE

_60

fruct

ose

bisp

hosp

hate

ald

olas

e33

696

9659

.349

.06

50.9

6.56

52.8

652

.12

2Le

ptoI

I_sc

aff_

8_G

EN

E_6

1di

hydr

olip

oam

ide

dehy

drog

enas

e49

7.7

104

104

18.7

78.

67.

16.

32

Lept

oII_

scaf

f_8_

GE

NE

_62

NA

D d

epen

dent

epi

mer

ase/

dehy

drat

ase

337.

746

204.

61.

531.

532

Lept

oII_

scaf

f_8_

GE

NE

_63

mal

tode

xtrin

pho

spho

ryla

se98

5.9

015

23.

51.

162

Lept

oII_

scaf

f_8_

GE

NE

_64

phos

phog

luco

mut

ase

606

00

19.4

10.4

67.

160.

82

Lept

oII_

scaf

f_8_

GE

NE

_66

cyto

chro

me

C o

xida

se h

eme

b an

d co

pper

-bin

ding

sub

unit

529

7777

11.3

9.7

4.33

22

Lept

oII_

scaf

f_8_

GE

NE

_69

ATP

ase

com

pone

nts

of A

BC

tran

spor

ters

62

60

042

.98.

222

.56

6.96

4.3

22

Lept

oII_

scaf

f_8_

GE

NE

_7A

BC

tran

spor

ter,

ATP

-bin

ding

pro

tein

27

655

5539

.32.

5614

.710

.93

36.4

22

Lept

oII_

scaf

f_8_

GE

NE

_70

uniq

ue h

ypot

hetic

al (1

41-1

, 8-7

0)11

7.9

89.5

48.0

338

.676

.551

.23

30.5

22

Lept

oII_

scaf

f_8_

GE

NE

_9ly

syl-t

RN

A s

ynth

etas

e 58

514

114

143

.422

.53

18.1

324

11.2

2Le

ptoI

I_sc

aff_

80_G

EN

E_1

0pr

ecor

rin-6

y m

ethy

lase

24

624

2131

5.06

16.9

618

.92

2Le

ptoI

I_sc

aff_

80_G

EN

E_1

1pr

ecor

rin-6

Y m

ethy

lase

23

840

4047

.317

.06

26.5

14.6

22

Lept

oII_

scaf

f_80

_GE

NE

_12

coba

lam

in b

iosy

nthe

sis

prot

ein

Cbi

G41

658

4420

.64.

65.

832.

632

2Le

ptoI

I_sc

aff_

80_G

EN

E_1

3pr

ecor

rin m

ethy

lase

30

787

8742

.920

.76

19.6

616

.73

22

Lept

oII_

scaf

f_80

_GE

NE

_14

cob(

i)ala

min

ade

nosy

ltran

sfer

ase

207

4545

70.9

21.9

618

.43

53.6

342

.52

2Le

ptoI

I_sc

aff_

80_G

EN

E_1

5po

lype

ptid

e de

form

ylas

e21

540

4078

.353

.853

.43

69.9

60.9

2Le

ptoI

I_sc

aff_

80_G

EN

E_1

6or

otid

ine

5`-p

hosp

hate

dec

arbo

xyla

se27

8.8

3434

11.6

2.4

3.86

2Le

ptoI

I_sc

aff_

80_G

EN

E_1

9co

nser

ved

hypo

thet

ical

(sim

ilar t

o th

iol:d

isul

fide

inte

rcha

nge

pr39

8.7

4820

.16.

33.

433.

266.

92

2Le

ptoI

I_sc

aff_

80_G

EN

E_2

2ph

osph

ate

bind

ing

perip

lasm

ic p

rote

in, A

BC

tran

spor

ter (

sim

ila42

1038

3862

.417

.618

.26

60.6

619

.23

16.7

22

Lept

oII_

scaf

f_80

_GE

NE

_24

Rub

isC

O-li

ke p

rote

in43

941

4153

.329

.16

32.3

31.8

636

.52

Lept

oII_

scaf

f_80

_GE

NE

_25

Mg-

prot

opor

phyr

in IX

mon

omet

hyl e

ster

oxi

dativ

e cy

clas

e59

7.7

031

4.3

1.43

2Le

ptoI

I_sc

aff_

80_G

EN

E_9

coba

lam

in b

iosy

nthe

sis

prot

ein

408.

977

7715

.72.

834.

732

2Le

ptoI

I_sc

aff_

81_G

EN

E_1

5re

com

bina

se/in

tegr

ase

(747

-3, 8

1-15

)41

9.8

6060

82.

662

Lept

oII_

scaf

f_81

_GE

NE

_19

oute

r mem

bran

e ef

flux

prot

ein

(sim

ilar t

o 79

1-1)

466.

823

231.

70.

562

Lept

oII_

scaf

f_81

_GE

NE

_21

catio

n ef

flux

syst

em p

rote

in11

79.

20

09.

52.

232.

82

Lept

oII_

scaf

f_81

_GE

NE

_22

uniq

ue h

ypot

hetic

al14

9.4

933

.324

.76

22

Lept

oII_

scaf

f_81

_GE

NE

_24

uniq

ue h

ypot

hetic

al15

1027

.115

.23

18.8

621

.714

.72

Lept

oII_

scaf

f_81

_GE

NE

_27

coup

ling

prot

ein

TraD

(81-

27, 1

15-1

)70

6.4

2726

8.1

3.3

22

Lept

oII_

scaf

f_81

_GE

NE

_5m

ethy

l-acc

eptin

g ch

emot

axis

pro

tein

116.

515

1413

.84.

69.

22

Lept

oII_

scaf

f_81

1_G

EN

E_3

type

IV s

ecre

tory

pat

hway

(811

-3, 1

113-

2)76

1050

233.

81.

262

Lept

oII_

scaf

f_81

5_G

EN

E_5

mob

iliza

tion

prot

ein

TraI

/Trw

c (1

078-

2, 8

15-5

)44

5.7

1111

16.1

2.23

3.03

8.3

22

Lept

oII_

scaf

f_82

4_G

EN

E_2

met

hyl-a

ccep

ting

chem

otax

is tr

ansd

ucer

75

5.7

00

13.2

2.53

3.16

22

Lept

oII_

scaf

f_83

9_G

EN

E_1

S-a

deno

sylh

omoc

yste

ine

hydr

olas

e (2

-71,

839

-1)

327

122

122

53.4

28.6

34.9

21.1

315

.92

2Le

ptoI

I_sc

aff_

839_

GE

NE

_2S

-ade

nosy

lmet

hion

ine

synt

heta

se (2

-72,

839

-2)

169

4747

69.8

49.2

54.4

325

.43

40.3

2Le

ptoI

I_sc

aff_

86_G

EN

E_1

0gl

ucos

e 1-

phos

phat

e th

ymid

yltra

nsfe

rase

335.

710

510

527

.814

.93

3.8

2Le

ptoI

I_sc

aff_

86_G

EN

E_1

1dT

DP

-glu

cose

4,6

-deh

ydra

tase

406.

911

811

711

.82.

436.

832

2Le

ptoI

I_sc

aff_

86_G

EN

E_1

2ac

onita

se/is

opro

pyl m

alat

e de

hydr

ogen

ase,

larg

e su

buni

t50

60

045

.626

.46

31.7

19.2

22.8

22

Lept

oII_

scaf

f_86

_GE

NE

_13

isop

ropy

l mal

ate

dehy

drog

enas

e, s

mal

l sub

unit

246

7070

61.5

43.1

45.6

639

.73

30.3

22

Lept

oII_

scaf

f_86

_GE

NE

_17

uniq

ue h

ypot

hetic

al21

511

.79.

435.

432

Lept

oII_

scaf

f_86

_GE

NE

_2(2

13-9

, 86-

2) m

alto

olig

osyl

treha

lose

syn

thas

e11

19.

10

163

8.8

1.96

0.96

2Le

ptoI

I_sc

aff_

86_G

EN

E_3

alph

a-am

ylas

e72

6.4

143

141

11.1

4.76

22

Lept

oII_

scaf

f_86

_GE

NE

_4gl

utam

ate

deca

rbox

ylas

e is

ozym

e 1

527

136

135

21.7

5.46

3.43

1.53

22

Lept

oII_

scaf

f_86

_GE

NE

_7co

nser

ved

hypo

thet

ical

3410

3826

.626

.62

Lept

oII_

scaf

f_86

_GE

NE

_9dT

DP

-4-d

ehyd

rorh

amno

se 3

,5-e

pim

eras

e20

6.2

5353

5.5

5.5

22

Lept

oII_

scaf

f_86

5_G

EN

E_2

uniq

ue h

ypot

hetic

al (s

imila

r to

630-

3)21

1049

.743

.416

.23

29.9

32

Lept

oII_

scaf

f_88

_GE

NE

_1ph

osph

orib

osyl

form

ylgl

ycin

amid

ine

synt

hase

II (8

8-1,

30-

2)79

6.1

115

108

26.7

11.3

68.

532.

32

Lept

oII_

scaf

f_88

_GE

NE

_12

uniq

ue h

ypot

hetic

al15

1027

.113

.93

13.4

32

2Le

ptoI

I_sc

aff_

88_G

EN

E_1

3rib

osom

al p

rote

in L

1715

1015

1580

.936

.63

60.5

615

.76

51.4

52.7

22

Lept

oII_

scaf

f_88

_GE

NE

_14

RN

A p

olym

eras

e36

591

9176

.236

.43

57.5

347

.93

32.7

22

Lept

oII_

scaf

f_88

_GE

NE

_15

ribos

omal

pro

tein

S4P

2210

5555

61.4

44.8

42.8

345

.538

.62

2Le

ptoI

I_sc

aff_

88_G

EN

E_1

6m

ethi

onin

e am

inop

eptid

ase

277

7675

38.5

9.13

12.8

327

.95.

62

2Le

ptoI

I_sc

aff_

88_G

EN

E_1

7ad

enyl

ate

kina

se25

856

5671

.257

.53

54.6

631

.23

55.1

37.4

2Le

ptoI

I_sc

aff_

88_G

EN

E_1

8se

cret

ion

prot

ein

Sec

Y48

9.9

145

145

4.8

2.2

2.2

22

Lept

oII_

scaf

f_88

_GE

NE

_19

ribos

omal

pro

tein

L15

109

1111

52.6

26.3

45.6

16.8

652

.652

.62

Lept

oII_

scaf

f_88

_GE

NE

_2am

idop

hosp

horib

osyl

trans

fera

se (8

8-2,

30-

1)55

5.7

153

151

25.2

57.

536.

532

2Le

ptoI

I_sc

aff_

88_G

EN

E_2

0un

ique

hyp

othe

tical

410

73.5

23.5

337

.26

4973

.573

.52

2Le

ptoI

I_sc

aff_

88_G

EN

E_3

uniq

ue h

ypot

hetic

al69

1047

.429

.522

.43

21.6

21.4

68.

22

2Le

ptoI

I_sc

aff_

88_G

EN

E_4

AD

P-L

-gly

cero

-D-m

anno

-hep

tose

-6-e

pim

eras

e34

6.2

8080

53.1

25.7

620

.56

10.1

311

.22

2Le

ptoI

I_sc

aff_

94_G

EN

E_1

1un

ique

hyp

othe

tical

255

23.5

7.53

12.8

37.

862

2Le

ptoI

I_sc

aff_

94_G

EN

E_1

2un

ique

hyp

othe

tical

2010

51.4

20.3

35.3

648

.845

.129

.12

2Le

ptoI

I_sc

aff_

94_G

EN

E_1

3co

bala

min

bio

synt

hesi

s pr

ecor

rin-3

met

hyla

se30

557

5742

.79.

830

.636

.33

2Le

ptoI

I_sc

aff_

94_G

EN

E_1

5pr

ecor

rin-2

C20

-met

hyltr

ansf

eras

e 27

839

3714

.73.

463.

332

Lept

oII_

scaf

f_94

_GE

NE

_17

ribof

lavi

n sy

ntha

se a

lpha

cha

in

235

3636

13.8

4.6

2Le

ptoI

I_sc

aff_

94_G

EN

E_1

8rib

ofla

vin

bios

ynth

esis

pro

tein

419.

578

7812

.24.

52

2Le

ptoI

I_sc

aff_

94_G

EN

E_1

9gl

ycyl

tRN

A s

ynth

etas

e, b

eta

subu

nit (

94-1

9, 3

17-1

)82

679

7926

5.63

16.7

62.

562

2Le

ptoI

I_sc

aff_

94_G

EN

E_5

uniq

ue h

ypot

hetic

al20

105

1.66

22

Lept

oII_

scaf

f_94

_GE

NE

_6di

hydr

oxya

cid

dehy

drat

ase

596

00

38.6

20.4

630

.76

22.4

20.1

22

Lept

oII_

scaf

f_94

_GE

NE

_7D

NA

reco

mbi

natio

n pr

otei

n rm

uC53

698

3220

.55.

739.

54.

062

Lept

oII_

scaf

f_94

_GE

NE

_9ca

tion

efflu

x sy

stem

pro

tein

459

5654

4.8

1.6

22

Lept

oII_

scaf

f_96

_GE

NE

_10

met

hylth

ioad

enos

ine

phos

phor

ylas

e 30

779

7935

.316

.43

20.4

616

.06

22

Lept

oII_

scaf

f_96

_GE

NE

_12

cell

divi

sion

cyc

le p

rote

in (C

DC

57)

3010

1715

58.3

2924

.46.

9617

.16

22

Lept

oII_

scaf

f_96

_GE

NE

_13

cons

erve

d hy

poth

etic

al (t

rans

crip

tion

regu

lato

r-lik

e)36

713

628

.411

.13

16.1

11.9

22

Lept

oII_

scaf

f_96

_GE

NE

_14

uniq

ue h

ypot

hetic

al (s

imila

r to

S-la

yer p

rote

ins)

3810

458

.850

.53

37.9

30.1

339

.436

.42

2Le

ptoI

I_sc

aff_

96_G

EN

E_3

tolQ

bio

poly

mer

tran

spor

t pro

tein

259

3535

3012

.56

20.9

3

2Le

ptoI

I_sc

aff_

96_G

EN

E_4

biop

olym

er tr

ansp

ort p

rote

in, T

olR

1710

2222

34.5

14.8

62.

936.

310

.12

2Le

ptoI

I_sc

aff_

96_G

EN

E_5

uniq

ue h

ypot

hetic

al31

113

26.6

5.73

15.7

19.0

612

.23

14.4

22

Lept

oII_

scaf

f_96

_GE

NE

_6pe

ripla

smic

Tol

B p

rote

in50

948

4871

.847

.33

28.8

610

.620

.86

22

Lept

oII_

scaf

f_96

_GE

NE

_7co

nser

ved

hypo

thet

ical

(TP

R re

peat

pro

tein

)30

914

61.7

52.2

44.7

625

.832

21.9

2Le

ptoI

I_sc

aff_

96_G

EN

E_8

DN

A m

ism

atch

repa

ir pr

otei

n M

utL

716.

385

855

1.66

22

Lept

oII_

scaf

f_98

_GE

NE

_1Ft

sH, c

ell d

ivis

ion

prot

ein/

met

allo

prot

ease

677

00

70.9

52.9

57.6

640

.86

28.1

22

Lept

oII_

scaf

f_98

_GE

NE

_10

uniq

ue h

ypot

hetic

al24

1047

.740

.841

.43

18.4

36.1

32

2Le

ptoI

I_sc

aff_

98_G

EN

E_1

1un

ique

hyp

othe

tical

4311

33.7

24.0

321

.526

.76

7.76

6.2

22

Lept

oII_

scaf

f_98

_GE

NE

_12

uniq

ue h

ypot

hetic

al27

1052

.550

.26

49.4

344

.86

47.7

642

.12

Lept

oII_

scaf

f_98

_GE

NE

_13

fusa

ric a

cid

deto

xific

atio

n pr

otei

n/ef

flux

trans

porte

r/per

mea

se

757

8415

5.3

1.76

22

Lept

oII_

scaf

f_98

_GE

NE

_15

Hly

D fa

mily

sec

retio

n pr

otei

n 34

1066

6111

3.66

2Le

ptoI

I_sc

aff_

98_G

EN

E_1

6un

ique

hyp

othe

tical

285.

225

252

Lept

oII_

scaf

f_98

_GE

NE

_19

pirin

336

9362

15.6

38.

6615

.62

Lept

oII_

scaf

f_98

_GE

NE

_3co

nser

ved

hypo

thet

ical

339.

751

8.9

2.96

2Le

ptoI

I_sc

aff_

98_G

EN

E_4

cons

erve

d hy

poth

etic

al26

1110

20.4

4.26

4.53

12.8

2Le

ptoI

I_sc

aff_

2_G

EN

E_3

4he

mol

ysin

/rRN

A m

ethy

lase

2710

4342

9.2

2.3

2Le

ptoI

I_sc

aff_

21_G

EN

E_2

8ou

ter m

embr

ane

efflu

x pr

otei

n72

6.7

9778

2.9

0.72

2Le

ptoI

I_sc

aff_

25_G

EN

E_5

2H

IT fa

mily

hyd

rola

se

196

3726

7.1

1.77

2Le

ptoI

I_sc

aff_

26_G

EN

E_2

2un

ique

hyp

othe

tical

346.

23.

40.

852

Lept

oII_

scaf

f_3_

GE

NE

_38

olig

opep

tide

AB

C tr

ansp

orte

r39

6.8

7373

112.

752

Lept

oII_

scaf

f_8_

GE

NE

_12

ferr

oche

lata

se

409

7272

7.3

1.82

2Le

ptoI

I_sc

aff_

8_G

EN

E_4

6L-

aspa

ragi

nase

336.

227

275.

51.

372

Lept

oII_

scaf

f_86

5_G

EN

E_1

uniq

ue h

ypot

hetic

al17

3.9

5.2

1.73

1.3

2Le

ptoI

I_sc

aff_

869_

GE

NE

_2un

ique

hyp

othe

tical

88.

124

.36.

07To

tal =

136

2 (1

431

- 69

dupl

icat

es)

2Le

ptoI

II_sc

aff_

101_

GE

NE

_17

trans

latio

n in

itiat

ion

fact

or IF

-316

9.3

3232

33.6

33.6

2Le

ptoI

II_sc

aff_

101_

GE

NE

_4ga

mm

a-gl

utam

yl p

hosp

hate

redu

ctas

e46

6.7

9898

4.3

1.43

22

Lept

oIII_

scaf

f_10

1_G

EN

E_8

ribos

omal

pro

tein

L27

1010

2525

32.6

15.9

35.

0622

.46

17.4

22

Lept

oIII_

scaf

f_10

2_G

EN

E_2

0m

ethy

l-acc

eptin

g ch

emot

axis

pro

tein

(L. f

erro

oxid

ans)

395

3131

8.7

2.06

4.96

2.06

2Le

ptoI

II_sc

aff_

102_

GE

NE

_5cy

toch

rom

e c

biog

enes

is/th

iore

doxi

n22

725

2512

.94.

32

Lept

oIII_

scaf

f_10

25_G

EN

E_1

xylu

lose

-5-p

hosp

hate

/fruc

tose

-6-p

hosp

hate

pho

spho

keto

lase

707.

20

05.

51.

730.

62

Lept

oIII_

scaf

f_10

70_G

EN

E_3

cons

erve

d hy

poth

etic

al33

859

9.9

3.3

2Le

ptoI

II_sc

aff_

1081

_GE

NE

_2Tr

wc

plas

mid

pro

tein

259

1515

11.6

7.73

2Le

ptoI

II_sc

aff_

1084

_GE

NE

_2un

ique

hyp

othe

tical

145

19.1

8.66

6.9

22

Lept

oIII_

scaf

f_11

1_G

EN

E_2

0ph

osph

ate

upta

ke re

gula

tor (

773-

6, 1

11-2

0)18

527

2410

.52.

065.

564.

136.

22

2Le

ptoI

II_sc

aff_

111_

GE

NE

_21

AB

C-ty

pe p

hosp

hate

tran

spor

t sys

tem

(111

-21,

773

-5)

206

9595

13.4

3.3

4.46

2Le

ptoI

II_sc

aff_

1115

_GE

NE

_3nu

cleo

side

dip

hosp

hate

kin

ase

189

4141

18.4

6.13

2Le

ptoI

II_sc

aff_

113_

GE

NE

_7gl

ycin

e cl

eava

ge s

yste

m p

rote

in P

sub

unit

236

7.1

8787

4.4

1.46

22

Lept

oIII_

scaf

f_11

7_G

EN

E_1

ribon

ucle

ase

III (8

53-3

, 117

-1)

147

1717

29.5

4.9

16.5

615

.76

2Le

ptoI

II_sc

aff_

117_

GE

NE

_11

pept

idyl

-pro

lyl c

is-tr

ans

isom

eras

e43

8.9

3126

10.5

3.5

2Le

ptoI

II_sc

aff_

117_

GE

NE

_13

pept

idyl

-pro

lyl c

is-tr

ans

isom

eras

e32

9.8

2114

43.3

7.16

18.6

122

Lept

oIII_

scaf

f_11

7_G

EN

E_1

8gl

utam

ate-

1-se

mia

ldeh

yde

amin

otra

nsfe

rase

486.

112

912

96.

73.

062

2Le

ptoI

II_sc

aff_

117_

GE

NE

_20

cons

erve

d hy

poth

etic

al21

1025

79.7

6.76

76.5

624

.46

2Le

ptoI

II_sc

aff_

1175

_GE

NE

_1al

do/k

eto

redu

ctas

e36

7.7

114

109

9.4

3.13

22

Lept

oIII_

scaf

f_12

3_G

EN

E_1

7gl

utam

ate

synt

hase

, sm

all s

ubun

it67

610

261

16.6

10.1

39.

22.

932

Lept

oIII_

scaf

f_12

3_G

EN

E_2

anth

rani

late

syn

thas

e co

mpo

nent

I55

5.7

105

105

2.2

0.73

2Le

ptoI

II_sc

aff_

123_

GE

NE

_7try

ptop

han

synt

hase

, bet

a su

buni

t 31

9.7

9794

16.2

5.4

2Le

ptoI

II_sc

aff_

127_

GE

NE

_1en

olas

e 20

5.3

5858

1812

2Le

ptoI

II_sc

aff_

127_

GE

NE

_12

low

mol

ecul

ar w

eigh

t hea

t sho

ck p

rote

in, H

sp20

175

2616

31.3

13.5

32

2Le

ptoI

II_sc

aff_

127_

GE

NE

_15

ribon

ucle

ase

PH

266

7270

55

1.66

2Le

ptoI

II_sc

aff_

127_

GE

NE

_18

AB

C tr

ansp

orte

r, A

TP-b

indi

ng p

rote

in66

5.7

118

118

3.5

1.16

2Le

ptoI

II_sc

aff_

127_

GE

NE

_3pe

ptid

ase,

M16

fam

ily47

9.4

4238

19.9

10.6

32

2Le

ptoI

II_sc

aff_

127_

GE

NE

_4pe

ptid

ase,

M16

fam

ily54

9.5

7070

113.

662

2Le

ptoI

II_sc

aff_

132_

GE

NE

_1le

ucyl

am

inop

eptid

ase

(sim

ilar t

o 26

-25,

189

-3)

509

9286

45.8

23.8

30.9

624

.83

222

Lept

oIII_

scaf

f_13

2_G

EN

E_2

ssrA

-bin

ding

pro

tein

(26-

24, 1

32-2

)19

1035

3547

.25.

9314

.53

32.3

2Le

ptoI

II_sc

aff_

144_

GE

NE

_1ty

pe I

rest

rictio

n-m

odifi

catio

n sy

stem

end

onuc

leas

e37

5.9

9893

4.2

1.4

2Le

ptoI

II_sc

aff_

144_

GE

NE

_4ty

pe I

rest

rictio

n sy

stem

spe

cific

ity p

rote

in62

6.3

8080

8.5

1.93

2.1

22

Lept

oIII_

scaf

f_14

4_G

EN

E_8

cons

erve

d hy

poth

etic

al (t

rans

crip

tiona

l reg

ulat

or d

omai

n)13

1022

46.6

16.1

5.73

22

Lept

oIII_

scaf

f_14

6_G

EN

E_1

1sq

uale

ne c

ycla

se20

627

279.

76.

462

Lept

oIII_

scaf

f_14

6_G

EN

E_7

trans

aldo

lase

42

690

9013

.42.

42.

062

Lept

oIII_

scaf

f_14

6_G

EN

E_8

trans

keto

lase

74

6.2

00

6.5

2.16

2.16

2Le

ptoI

II_sc

aff_

151_

GE

NE

_13

UD

P-N

-ace

tylm

uram

oyla

lany

l-D-g

luta

mat

e--2

,6- d

iam

inop

imel

a28

5.8

6262

13.8

4.6

2Le

ptoI

II_sc

aff_

158_

GE

NE

_2di

enel

acto

ne h

ydro

lase

28

734

2332

.97.

562.

965

2Le

ptoI

II_sc

aff_

158_

GE

NE

_5so

lubl

e in

orga

nic

pyro

phos

phat

ase

215.

749

4635

14.9

64.

362

2Le

ptoI

II_sc

aff_

179_

GE

NE

_1ch

emot

axis

pro

tein

24

615

1536

.15.

569.

739.

72

Lept

oIII_

scaf

f_17

9_G

EN

E_1

2di

hydr

ooro

tate

deh

ydro

gena

se39

5.9

6457

9.1

3.03

2Le

ptoI

II_sc

aff_

181_

GE

NE

_12

uniq

ue h

ypot

hetic

al27

7.9

5.4

1.8

2Le

ptoI

II_sc

aff_

181_

GE

NE

_17

IstB

hel

per p

rote

in/tr

ansp

osas

e29

9.2

6767

7.4

2.46

22

Lept

oIII_

scaf

f_18

1_G

EN

E_2

uniq

ue h

ypot

hetic

al (1

92-1

4, 1

81-2

)43

48.

58.

52.

832

22

Lept

oIII_

scaf

f_18

1_G

EN

E_7

uniq

ue h

ypot

hetic

al (s

imila

rity

to c

ytoc

hrom

e c)

178

312

.312

.310

.43

6.7

6.7

6.7

22

Lept

oIII_

scaf

f_18

7_G

EN

E_1

phos

phoe

nolp

yruv

ate

synt

hase

375

130

130

43.6

8.46

19.8

9.4

2Le

ptoI

II_sc

aff_

187_

GE

NE

_12

trans

posa

se-li

ke57

9.1

1010

4.3

1.43

2Le

ptoI

II_sc

aff_

188_

GE

NE

_11

cons

erve

d hy

poth

etic

al34

7.1

5010

.13.

362

Lept

oIII_

scaf

f_18

8_G

EN

E_2

mol

ybde

num

AB

C tr

ansp

orte

r, pe

ripla

smic

com

pone

nt27

1045

4518

.56.

162

Lept

oIII_

scaf

f_19

2_G

EN

E_4

cons

erve

d hy

po (s

imila

r to

ferr

oche

lata

se, H

emH

)37

5.7

1929

.37.

66

22

Lept

oIII_

scaf

f_19

9_G

EN

E_7

cons

erve

d hy

poth

etic

al50

8.5

5520

.18.

211

.93.

962

Lept

oIII_

scaf

f_20

1_G

EN

E_1

uniq

ue h

ypot

hetic

al7

1036

.112

.03

22

Lept

oIII_

scaf

f_20

1_G

EN

E_1

0m

ethy

l-acc

eptin

g ch

emot

axis

pro

tein

246

1414

7.2

3.53

5.3

3.53

7.2

2Le

ptoI

II_sc

aff_

201_

GE

NE

_3fla

gella

r hoo

k-as

soci

ated

pro

tein

160

6.6

3939

13.2

1.73

1.96

2.03

22

Lept

oIII_

scaf

f_20

1_G

EN

E_6

flage

llin

FliC

(sim

ilar t

o 31

3-2)

309

5252

58.5

45.8

45.7

43.6

322

.03

22

Lept

oIII_

scaf

f_21

1_G

EN

E_1

met

hyl-a

ccep

ting

chem

otax

is p

rote

in

629

4545

22.8

5.3

10.3

1.33

2Le

ptoI

II_sc

aff_

211_

GE

NE

_11

flage

llar h

ook

basa

l-bod

y pr

otei

n Fl

gG28

968

6816

.15.

366.

42

Lept

oIII_

scaf

f_21

1_G

EN

E_1

3fla

gella

r P-r

ing

prot

ein

FlgI

3711

5454

5.6

1.86

2Le

ptoI

II_sc

aff_

211_

GE

NE

_2pu

rine-

bind

ing

chem

otax

is p

rote

in C

heW

205

2525

375.

168.

662

Lept

oIII_

scaf

f_22

0_G

EN

E_5

gluc

osam

ine-

-fruc

tose

-6-p

hosp

hate

am

inot

rans

fera

se65

5.7

145

145

2.1

0.7

22

Lept

oIII_

scaf

f_22

0_G

EN

E_9

uniq

ue h

ypot

hetic

al (2

20-9

, 660

-8)

456

55.6

33.8

32

Lept

oIII_

scaf

f_22

5_G

EN

E_7

hist

idyl

-tRN

A s

ynth

etas

e47

6.7

9696

5.3

1.76

2Le

ptoI

II_sc

aff_

229_

GE

NE

_3gl

utam

ate

synt

hase

156

6.3

00

40.

731.

832

2Le

ptoI

II_sc

aff_

233_

GE

NE

_2m

ethy

l-acc

eptin

g ch

emot

axis

pro

tein

436

4140

171.

862.

86.

562

Lept

oIII_

scaf

f_23

7_G

EN

E_1

prot

ein

disu

lfide

isom

eras

e38

910

1015

.75.

232

Lept

oIII_

scaf

f_23

7_G

EN

E_6

phos

phat

e st

arva

tion-

indu

cibl

e pr

otei

n38

8.6

8482

3.2

1.06

2Le

ptoI

II_sc

aff_

242_

GE

NE

_3as

party

l-tR

NA

syn

thet

ase

665.

817

317

38.

96.

82

2Le

ptoI

II_sc

aff_

242_

GE

NE

_5gl

utam

ine

synt

heta

se I

586

00

35.2

9.06

16.5

31.

832

2Le

ptoI

II_sc

aff_

251_

GE

NE

_9pe

ptid

ogly

can

acet

ylat

ion/

isop

reno

id b

iosy

nthe

sis

416

115

114

10.6

2.5

6.3

2.5

22

Lept

oIII_

scaf

f_26

6_G

EN

E_1

0un

ique

hyp

othe

tical

1510

27.5

10.1

317

.86

2Le

ptoI

II_sc

aff_

266_

GE

NE

_11

ribon

ucle

ase

R66

5.9

116

107

3.6

1.2

2Le

ptoI

II_sc

aff_

266_

GE

NE

_13

cons

erve

d hy

poth

etic

al (3

32-4

, 266

-13)

117

2961

.344

.43

2Le

ptoI

II_sc

aff_

290_

GE

NE

_2S

-ade

nosy

lmet

hion

ine

synt

heta

se42

5.8

137

137

19.2

6.53

10.6

2Le

ptoI

II_sc

aff_

290_

GE

NE

_4S

-ade

nosy

lhom

ocys

tein

e hy

drol

ase

248

8585

17.2

5.73

11.4

62

2Le

ptoI

II_sc

aff_

290_

GE

NE

_9th

reon

ine

synt

hase

47

815

715

726

.23.

216

.26

5.8

11.3

22

Lept

oIII_

scaf

f_29

3_G

EN

E_3

dihy

drod

ipic

olin

ate

synt

hase

327.

381

8115

.66.

24.

332

2Le

ptoI

II_sc

aff_

293_

GE

NE

_6am

inot

rans

fera

se43

813

113

128

.59.

838.

32

Lept

oIII_

scaf

f_29

6_G

EN

E_2

uniq

ue h

ypot

hetic

al34

8.1

65

1.66

22

Lept

oIII_

scaf

f_30

2_G

EN

E_1

acon

itase

45

715

515

565

.726

38.2

25.8

252

Lept

oIII_

scaf

f_30

2_G

EN

E_1

0un

ique

hyp

othe

tical

(302

-10,

507

-3, 7

98-7

)20

9.5

227.

332

Lept

oIII_

scaf

f_30

2_G

EN

E_2

citra

te s

ynth

ase

298.

766

6625

.34.

34

6.9

22

Lept

oIII_

scaf

f_30

2_G

EN

E_6

succ

inat

e de

hydr

ogen

ase

576.

213

066

5.6

1.3

1.7

22

Lept

oIII_

scaf

f_30

2_G

EN

E_7

succ

inyl

-coA

syn

thet

ase

436

122

122

233

11.3

3.6

22

Lept

oIII_

scaf

f_30

2_G

EN

E_8

succ

inyl

-coA

syn

thet

ase

(507

-1, 3

02-8

)32

610

010

025

.913

.211

.93.

512

.58.

92

2Le

ptoI

II_sc

aff_

302_

GE

NE

_9pe

roxi

redo

xin

(507

-2, 3

02-9

)17

6.6

2822

47.1

10.6

620

.53.

2621

.33

172

2Le

ptoI

II_sc

aff_

309_

GE

NE

_2ba

cter

iofe

rret

in (1

056-

3, 3

09-2

)18

940

4051

.56.

2314

.03

172

2Le

ptoI

II_sc

aff_

309_

GE

NE

_3co

nser

ved

hypo

thet

ical

(pro

hibi

tin-li

ke)

309

329

5640

.136

.86

2.63

16.6

62

Lept

oIII_

scaf

f_30

9_G

EN

E_4

uniq

ue h

ypot

hetic

al21

9.6

28.9

3.03

8.13

4.06

2Le

ptoI

II_sc

aff_

309_

GE

NE

_6un

ique

hyp

othe

tical

149.

915

.77.

862

Lept

oIII_

scaf

f_31

2_G

EN

E_5

uniq

ue h

ypot

hetic

al (s

imila

r to

perip

lasm

ic c

hape

rone

Lol

A)

2511

88

11.7

3.9

22

Lept

oIII_

scaf

f_31

3_G

EN

E_2

flage

llin

FliC

(sim

ilar t

o 20

1-6)

309

5252

6046

.43

51.8

650

.324

.83

22

Lept

oIII_

scaf

f_31

4_G

EN

E_4

trans

crip

tion

elon

gatio

n fa

ctor

186

3939

15.2

10.1

313

.315

.22

2Le

ptoI

II_sc

aff_

315_

GE

NE

_7m

ethy

l-acc

eptin

g ch

emot

axis

pro

tein

586

3432

2.1

1.4

2.1

1.4

22

Lept

oIII_

scaf

f_32

0_G

EN

E_1

0H

scA

cha

pero

ne59

5.2

00

10.7

3.26

2.76

5.2

22

Lept

oIII_

scaf

f_32

0_G

EN

E_6

cyst

eine

des

ulfu

rase

/am

inot

rans

fera

se44

613

413

48.

73.

44.

162

Lept

oIII_

scaf

f_32

0_G

EN

E_7

nifU

pro

tein

14

651

5139

.15.

219

.53

24.2

2Le

ptoI

II_sc

aff_

323_

GE

NE

_5tri

gger

fact

or (c

hape

rone

)49

5.2

1010

10.1

3.4

22

Lept

oIII_

scaf

f_32

3_G

EN

E_7

ATP

-dep

ende

nt C

lp p

rote

ase

ATP

-bin

ding

sub

unit

(323

-7, 8

8239

5.4

130

130

21.4

7.1

12.6

2Le

ptoI

II_sc

aff_

324_

GE

NE

_4ex

cinu

clea

se A

BC

, B s

ubun

it79

5.6

00

1.3

0.86

22

Lept

oIII_

scaf

f_32

5_G

EN

E_1

0fe

rrid

oxin

oxi

dore

duct

ase

326

9999

30.6

11.6

622

.53

4.2

25.1

32

2Le

ptoI

II_sc

aff_

325_

GE

NE

_11

ferr

idox

in o

xido

redu

ctas

e27

671

7113

.913

.913

.913

.910

.12

Lept

oIII_

scaf

f_32

5_G

EN

E_2

uniq

ue h

ypot

hetic

al18

9.4

21.8

7.26

22

Lept

oIII_

scaf

f_32

5_G

EN

E_9

ferr

edox

in o

xido

redu

ctas

e, g

amm

a su

buni

t25

969

6965

.116

.922

.13

45.7

12.2

2Le

ptoI

II_sc

aff_

332_

GE

NE

_1un

ique

hyp

othe

tical

1611

4237

.17.

12

Lept

oIII_

scaf

f_33

2_G

EN

E_4

cons

erve

d hy

poth

etic

al (

266-

13, 3

32-4

)11

6.6

2861

.344

.43

22

Lept

oIII_

scaf

f_33

9_G

EN

E_1

plas

toqu

inol

--pl

asto

cyan

in re

duct

ase/

Rie

ske

Fe-S

pro

tein

(123

239.

415

1157

.323

.618

.39.

415

2Le

ptoI

II_sc

aff_

339_

GE

NE

_5un

ique

hyp

othe

tical

(sim

ilar t

o cy

toch

rom

e c)

368.

59.

71.

13.

22

Lept

oIII_

scaf

f_34

5_G

EN

E_3

sens

ory

box

prot

ein

745.

114

152

4.3

1.43

2Le

ptoI

II_sc

aff_

351_

GE

NE

_10

trans

crip

tiona

l reg

ulat

or13

7.7

1212

16.8

5.6

2Le

ptoI

II_sc

aff_

351_

GE

NE

_7co

nser

ved

hypo

thet

ical

205.

740

19.5

6.5

2Le

ptoI

II_sc

aff_

370_

GE

NE

_2ur

opor

phyr

inog

en d

ecar

boxy

lase

397.

795

954.

91.

632

2Le

ptoI

II_sc

aff_

370_

GE

NE

_7m

ethy

ltran

sfer

ase/

Fe-S

oxi

dore

duct

ase

556.

415

047

9.7

2.26

2.26

22

Lept

oIII_

scaf

f_37

2_G

EN

E_1

cons

erve

d hy

poth

etic

al (6

57-2

, 372

-1)

227

5143

.920

.73

8.33

18.8

62

Lept

oIII_

scaf

f_37

2_G

EN

E_2

mol

ybde

num

AB

C tr

ansp

orte

r, so

lute

-bin

ding

pro

tein

(657

-1, 3

3610

8911

9.7

3.23

2Le

ptoI

II_sc

aff_

375_

GE

NE

_4ou

ter m

embr

ane

efflu

x pr

otei

n33

5.6

2317

18.3

6.1

2Le

ptoI

II_sc

aff_

377_

GE

NE

_1rib

osom

al p

rote

in S

2 (7

74-1

, 377

-1)

239.

355

5460

.84.

89.

121

.72

Lept

oIII_

scaf

f_37

7_G

EN

E_2

trans

latio

n el

onga

tion

fact

or T

s22

5.9

4848

5926

.55.

32.

7331

.12

Lept

oIII_

scaf

f_37

7_G

EN

E_3

urid

ylat

e ki

nase

246.

676

7514

.94.

962

Lept

oIII_

scaf

f_37

7_G

EN

E_4

ribos

ome

recy

clin

g fa

ctor

218.

838

3827

.19.

032

Lept

oIII_

scaf

f_37

7_G

EN

E_8

cons

. hyp

o (s

imila

r to

AB

C tr

ansp

orte

r sub

stra

te b

indi

ng p

rote

i34

8.6

359

22.7

7.06

4.03

2Le

ptoI

II_sc

aff_

383_

GE

NE

_1se

nsor

y bo

x pr

otei

n10

38.

852

273.

61.

22

Lept

oIII_

scaf

f_38

3_G

EN

E_5

aden

ylos

ucci

nate

syn

thet

ase

198.

651

4910

.83.

62

2Le

ptoI

II_sc

aff_

390_

GE

NE

_5gl

utam

yl-tR

NA

(Gln

) am

idot

rans

fera

se55

612

712

76.

74.

632

Lept

oIII_

scaf

f_39

0_G

EN

E_8

enol

ase

345.

110

310

310

.46.

932

Lept

oIII_

scaf

f_39

7_G

EN

E_4

suga

r kin

ase

566.

971

487.

62.

532.

532

Lept

oIII_

scaf

f_39

8_G

EN

E_2

uniq

ue h

ypot

hetic

al66

5.9

513

.86.

22

2Le

ptoI

II_sc

aff_

401_

GE

NE

_2he

licas

e61

683

834.

21.

42

Lept

oIII_

scaf

f_40

8_G

EN

E_3

uniq

ue h

ypot

hetic

al13

28.

94.

80.

531.

062

Lept

oIII_

scaf

f_41

5_G

EN

E_3

oute

r mem

bran

e ef

flux

prot

ein

111

9.6

123

123

2.1

0.7

2Le

ptoI

II_sc

aff_

415_

GE

NE

_4un

ique

hyp

othe

tical

249

47.9

24.8

7.9

2Le

ptoI

II_sc

aff_

416_

GE

NE

_2ad

enyl

ylsu

lfate

redu

ctas

e, s

ubun

it A

328.

585

7714

.43.

563.

910

.72

2Le

ptoI

II_sc

aff_

416_

GE

NE

_3ad

enyl

sulfa

te re

duct

ase,

sub

unit

B13

512

1231

.910

.63

2Le

ptoI

II_sc

aff_

416_

GE

NE

_4su

lfate

ade

nyly

ltran

sfer

ase

446.

512

212

29.

33.

12

Lept

oIII_

scaf

f_41

8_G

EN

E_7

argi

nino

succ

inat

e sy

ntha

se

466.

513

413

46.

32.

12

Lept

oIII_

scaf

f_42

1_G

EN

E_2

pept

idog

lyca

n gl

ycos

yltra

nsfe

rase

519.

880

665.

21.

732

Lept

oIII_

scaf

f_42

1_G

EN

E_5

cons

erve

d hy

poth

etic

al (s

imila

r to

cyto

chro

me

c)29

9.5

6915

.46

22

Lept

oIII_

scaf

f_42

1_G

EN

E_8

glyc

eral

dehy

de-3

-pho

spha

te d

ehyd

roge

nase

377

115

115

32.3

6.33

9.96

11.4

37

2Le

ptoI

II_sc

aff_

425_

GE

NE

_1co

nser

ved

hypo

thet

ical

126.

110

33.6

11.2

2Le

ptoI

II_sc

aff_

427_

GE

NE

_1un

ique

hyp

othe

tical

1211

33.6

11.2

2Le

ptoI

II_sc

aff_

427_

GE

NE

_2un

ique

hyp

othe

tical

279

29.7

24.2

62

Lept

oIII_

scaf

f_42

7_G

EN

E_3

phos

phog

luco

mut

ase

596.

118

018

06.

16.

12

Lept

oIII_

scaf

f_43

7_G

EN

E_1

6-ph

osph

oglu

cona

te d

ehyd

roge

nase

238.

570

6710

.13.

362

2Le

ptoI

II_sc

aff_

437_

GE

NE

_4un

ique

hyp

othe

tical

2610

50.6

43.4

43.5

322

.13

7.8

2Le

ptoI

II_sc

aff_

437_

GE

NE

_5un

ique

hyp

othe

tical

559.

635

.62.

262.

1320

.23

2Le

ptoI

II_sc

aff_

437_

GE

NE

_6un

ique

hyp

othe

tical

119

41.5

21.3

19.1

32

Lept

oIII_

scaf

f_45

1_G

EN

E_3

uniq

ue h

ypot

hetic

al (s

imila

r to

O-m

ethy

ltran

sfer

ase)

236.

76

552

.94

23.7

32

2Le

ptoI

II_sc

aff_

453_

GE

NE

_7Fe

(III)

redu

ctas

e, b

eta

subu

nit

575.

886

8317

.88.

8310

.12.

32

Lept

oIII_

scaf

f_46

5_G

EN

E_1

trans

crip

tion

term

inat

ion

fact

or

155.

945

4551

.54.

620

212

Lept

oIII_

scaf

f_46

5_G

EN

E_7

UD

P-N

-ace

tylg

luco

sam

ine

1-ca

rbox

yvin

yltra

nsfe

rase

176.

542

425.

81.

932

Lept

oIII_

scaf

f_47

1_G

EN

E_4

phos

phog

lyce

rate

mut

ase

247.

254

5414

.54.

832

2Le

ptoI

II_sc

aff_

471_

GE

NE

_8A

TPas

e in

volv

ed in

chr

omos

ome

parti

tioni

ng39

688

8820

.88

12.6

3.26

2Le

ptoI

II_sc

aff_

472_

GE

NE

_3un

ique

hyp

othe

tical

396.

86.

22.

062

Lept

oIII_

scaf

f_47

3_G

EN

E_6

uniq

ue h

ypot

hetic

al19

1024

.816

.3

22

Lept

oIII_

scaf

f_48

5_G

EN

E_2

ferr

edox

in o

xido

redu

ctas

e10

1073

7365

.419

.913

.56

36.8

2Le

ptoI

II_sc

aff_

485_

GE

NE

_3su

buni

t of p

yruv

ate:

ferr

edox

in o

xido

redu

tase

158.

642

4229

.15.

736.

962

2Le

ptoI

II_sc

aff_

485_

GE

NE

_5fe

rred

oxin

oxi

dore

duct

ase,

alp

ha s

ubun

it46

613

713

720

.57.

1610

.83.

42

Lept

oIII_

scaf

f_48

5_G

EN

E_6

uniq

ue h

ypot

hetic

al22

5.5

11.6

3.86

2Le

ptoI

II_sc

aff_

486_

GE

NE

_2D

NA

gyr

ase,

A s

ubun

it92

6.2

00

7.3

2.36

4.23

2.4

2Le

ptoI

II_sc

aff_

486_

GE

NE

_3D

NA

gyr

ase,

B s

ubun

it60

5.9

168

167

6.8

4.56

2Le

ptoI

II_sc

aff_

500_

GE

NE

_4co

nser

ved

hypo

thet

ical

465.

441

4.3

1.43

0.8

2Le

ptoI

II_sc

aff_

500_

GE

NE

_7di

hydr

ofla

vono

l 4-r

educ

tase

398.

785

777

2.33

22

Lept

oIII_

scaf

f_50

7_G

EN

E_1

succ

inyl

-coA

syn

thet

ase

(302

-8, 5

07-1

)14

60

024

.32.

937.

836.

42

2Le

ptoI

II_sc

aff_

507_

GE

NE

_2pe

roxi

redo

xin

(302

-9, 5

07-2

)17

628

2247

.110

.66

20.5

3.26

21.3

317

2Le

ptoI

II_sc

aff_

507_

GE

NE

_3un

ique

hyp

othe

tical

(302

-10,

507

-3, 7

98-7

)20

9.9

227.

332

Lept

oIII_

scaf

f_51

2_G

EN

E_6

uniq

ue h

ypot

hetic

al20

1032

.417

.03

2Le

ptoI

II_sc

aff_

518_

GE

NE

_1un

ique

hyp

othe

tical

337.

13.

41.

132

2Le

ptoI

II_sc

aff_

519_

GE

NE

_8ac

etol

acta

te s

ynth

ase,

larg

e su

buni

t, bi

osyn

thet

ic ty

pe46

6.1

154

154

10.8

7.13

61.

662

2Le

ptoI

II_sc

aff_

527_

GE

NE

_1tra

nsla

tion

elon

gatio

n fa

ctor

(640

-9, 5

27-1

, sim

ilar t

o 13

7-1,

71

167

6868

89.4

58.4

59.9

51.4

692

Lept

oIII_

scaf

f_52

7_G

EN

E_4

shuf

flon-

spec

ific

reco

mbi

nase

3910

5959

21.7

28.

17.

52

Lept

oIII_

scaf

f_52

9_G

EN

E_5

uniq

ue h

ypot

hetic

al16

6.8

33.3

19.8

32

2Le

ptoI

II_sc

aff_

533_

GE

NE

_3A

AA

-fam

ily A

TPas

e 44

611

211

217

.22.

637.

637.

232

2Le

ptoI

II_sc

aff_

535_

GE

NE

_1N

AD

H d

ehyd

roge

nase

I, G

sub

unit

255.

356

5317

.916

.117

.73

22

Lept

oIII_

scaf

f_53

5_G

EN

E_2

NA

DH

deh

ydro

gena

se I,

F s

ubun

it60

60

020

.24.

3310

.56

1.86

9.5

22

Lept

oIII_

scaf

f_53

5_G

EN

E_7

NA

DH

deh

ydro

gena

se I,

C s

ubun

it21

5.5

2626

29.1

9.53

8.96

12.5

62

2Le

ptoI

II_sc

aff_

535_

GE

NE

_8N

AD

H d

ehyd

roge

nase

, sub

unit

B18

856

5650

.916

.76

8.86

23.4

32

Lept

oIII_

scaf

f_53

8_G

EN

E_1

nucl

eosi

de-d

ipho

spha

te-s

ugar

epi

mer

ase

207

2711

.83.

61.

67

22

Lept

oIII_

scaf

f_54

_GE

NE

_1A

TP s

ynth

ase,

alp

ha s

ubun

it49

616

616

636

12.5

319

.29.

536.

62

Lept

oIII_

scaf

f_54

_GE

NE

_12

gala

ctos

e-1-

phos

phat

e ur

idyl

yltra

nsfe

rase

386.

210

195

8.7

2.6

6.8

22

Lept

oIII_

scaf

f_54

_GE

NE

_13

cons

erve

d hy

poth

etic

al (s

imila

r to

fruct

ose-

bisp

hosp

hate

ald

ola

516.

511

422

.46.

462.

42

Lept

oIII_

scaf

f_54

_GE

NE

_15

uniq

ue h

ypot

hetic

al14

5.4

268.

662

Lept

oIII_

scaf

f_54

_GE

NE

_16

gluc

oam

ylas

e76

5.4

133

133

3.4

1.13

2Le

ptoI

II_sc

aff_

54_G

EN

E_1

7ef

flux

trans

porte

r, R

ND

fam

ily, M

FP s

ubun

it42

9.8

5725

93

2Le

ptoI

II_sc

aff_

54_G

EN

E_1

8ca

tion

efflu

x sy

stem

, Acr

B/A

crD

/Acr

F fa

mily

399.

467

506.

12.

032

2Le

ptoI

II_sc

aff_

54_G

EN

E_2

ATP

syn

thas

e, s

ubun

it ga

mm

a33

1063

6228

.86.

2610

.63

2Le

ptoI

II_sc

aff_

54_G

EN

E_2

1ca

tion

efflu

x sy

stem

pro

tein

469.

511

734

8.8

2.93

22

Lept

oIII_

scaf

f_54

_GE

NE

_22

oute

r mem

bran

e ef

flux

prot

ein

579

1313

38.9

21.6

24.9

33.

82

Lept

oIII_

scaf

f_54

_GE

NE

_23

thio

redo

xin

redu

ctas

e34

5.4

9090

11.3

3.76

22

Lept

oIII_

scaf

f_54

_GE

NE

_3A

TP s

ynth

ase,

bet

a su

buni

t50

50

040

.325

.96

29.2

626

.83

192

Lept

oIII_

scaf

f_54

_GE

NE

_4A

TP s

ynth

ase

epsi

lon

chai

n16

5.5

1515

20.1

12.9

62

Lept

oIII_

scaf

f_54

_GE

NE

_7gl

ucos

e-1-

phos

phat

e ad

enyl

yltra

nsfe

rase

476.

911

311

37.

22.

42

2Le

ptoI

II_sc

aff_

563_

GE

NE

_1A

BC

tran

spor

ter,

ATP

-bin

ding

pro

tein

(sim

ilar t

o 41

6-9)

565.

20

011

.10.

733.

761.

42

Lept

oIII_

scaf

f_56

4_G

EN

E_2

uniq

ue h

ypot

hetic

al32

6.4

21.7

12.0

62

2Le

ptoI

II_sc

aff_

564_

GE

NE

_5gl

utam

ine

synt

heta

se a

ctiv

ity re

gula

tion

prot

ein

129

3231

59.8

30.0

67.

7331

.86

18.8

22

Lept

oIII_

scaf

f_56

4_G

EN

E_7

cons

erve

d hy

poth

etic

al18

453

206.

6613

.33

22

Lept

oIII_

scaf

f_56

5_G

EN

E_3

DN

A re

pair

prot

ein

Rec

A26

793

9321

.22.

7616

.93

8.86

2Le

ptoI

II_sc

aff_

576_

GE

NE

_3ou

ter m

embr

ane

efflu

x pr

otei

n55

5.9

2020

18.7

1.66

6.46

22

Lept

oIII_

scaf

f_57

7_G

EN

E_5

cell

divi

sion

pro

tein

Fts

H57

60

045

.622

.624

.86

21.0

38.

32

2Le

ptoI

II_sc

aff_

583_

GE

NE

_1R

ubis

CO

, lar

ge s

ubun

it (6

85-2

, 583

-1)

349

4342

14.2

6.76

2.7

3.86

11.6

2Le

ptoI

II_sc

aff_

583_

GE

NE

_4co

nser

ved

hypo

thet

ical

(sim

ilar t

o 77

4-4,

540

-1, 1

87-1

4, 1

51-1

5710

136

4.6

1.53

2Le

ptoI

II_sc

aff_

594_

GE

NE

_5rib

ose-

phos

phat

e py

roph

osph

okin

ase

248

7575

18.1

12.1

2Le

ptoI

II_sc

aff_

594_

GE

NE

_6rib

osom

a pr

otei

n L2

513

1016

1543

.58.

69.

42

Lept

oIII_

scaf

f_60

2_G

EN

E_2

trans

posa

se16

8.8

2926

13.3

4.43

2Le

ptoI

II_sc

aff_

607_

GE

NE

_1ou

ter m

embr

ane

prot

ein

a20

1010

1027

.311

.16

72

Lept

oIII_

scaf

f_60

7_G

EN

E_4

UTP

-glu

cose

-1-p

hosp

hate

urid

ylyl

trans

fera

se33

5.7

9393

31.4

9.13

6.53

2Le

ptoI

II_sc

aff_

61_G

EN

E_2

6se

rine

prot

ease

539.

993

9125

.82.

332

8.3

2Le

ptoI

II_sc

aff_

61_G

EN

E_3

1un

ique

hyp

othe

tical

259.

832

.65.

735.

132

2Le

ptoI

II_sc

aff_

638_

GE

NE

_4co

nser

ved

hypo

thet

ical

(TP

R re

peat

pro

tein

)33

912

34.9

6.5

6.06

3.9

2Le

ptoI

II_sc

aff_

639_

GE

NE

_2L-

lysi

ne 2

,3-a

min

omut

ase

465.

410

395

6.6

2.2

22

Lept

oIII_

scaf

f_64

0_G

EN

E_1

ribos

omal

pro

tein

L12

(640

-1, 7

96-3

)10

5.1

1313

88.9

34.4

41.8

43.1

6361

.62

2Le

ptoI

II_sc

aff_

640_

GE

NE

_2rib

osom

al p

rote

in L

10 (6

40-2

, 796

-2)

199.

722

2239

.35

22.7

22

Lept

oIII_

scaf

f_64

0_G

EN

E_4

ribos

omal

pro

tein

L11

(640

-4, 1

37-3

)15

9.7

4645

41.8

2.4

11.3

2.4

24.1

7.1

2Le

ptoI

II_sc

aff_

640_

GE

NE

_5tra

nscr

iptio

n an

titer

min

atio

n pr

otei

n20

5.7

4040

72.3

5.5

24.1

22

Lept

oIII_

scaf

f_64

0_G

EN

E_9

elon

gatio

n fa

ctor

Tu

(527

-1, 6

40-9

)29

5.4

119

116

84.8

49.6

50.7

44.3

49.6

2Le

ptoI

II_sc

aff_

655_

GE

NE

_1R

NA

pol

ymer

ase

sigm

a-54

fact

or55

4.8

7874

2.5

0.83

22

Lept

oIII_

scaf

f_65

5_G

EN

E_5

mal

ate

dehy

drog

enas

e35

685

8528

.815

.53

22.8

21.5

612

.52

Lept

oIII_

scaf

f_65

7_G

EN

E_1

cons

erve

d hy

poth

etic

al23

1054

15.1

5.03

22

Lept

oIII_

scaf

f_65

7_G

EN

E_2

cons

erve

d hy

poth

etic

al (6

57-2

, 372

-1)

299.

353

32.2

15.2

36.

1313

.86

2Le

ptoI

II_sc

aff_

660_

GE

NE

_8un

ique

hyp

othe

tical

(220

-9, 6

60-8

)12

1167

.938

.83

2Le

ptoI

II_sc

aff_

672_

GE

NE

_2al

coho

l deh

ydro

gena

se38

715

715

74.

34.

32.

862.

864.

32

Lept

oIII_

scaf

f_67

2_G

EN

E_3

two-

com

pone

nt re

spon

se re

gula

tor

396.

547

367.

82.

62

Lept

oIII_

scaf

f_68

0_G

EN

E_1

sigm

a-54

dep

ende

nt D

NA

-bin

ding

resp

onse

regu

lato

r32

4.9

6866

3.8

1.26

22

Lept

oIII_

scaf

f_68

0_G

EN

E_3

uniq

ue h

ypot

hetic

al (s

imila

r to

isoc

itrat

e de

hydr

ogen

ase)

139

99

50.4

34.4

631

.56

29.8

343

.16

27.8

22

Lept

oIII_

scaf

f_68

0_G

EN

E_4

isoc

itrat

e de

hydr

ogen

ase

376

101

101

74.4

43.0

348

.76

38.1

628

.32

Lept

oIII_

scaf

f_68

1_G

EN

E_2

valy

l-tR

NA

syn

thet

ase

101

5.7

00

1.3

0.43

2Le

ptoI

II_sc

aff_

685_

GE

NE

_2rib

ulos

e bi

spho

spha

te c

arbo

xyla

se, l

arge

sub

unit

239.

326

2412

.77.

22

2Le

ptoI

II_sc

aff_

703_

GE

NE

_1in

osin

e-5'

-mon

opho

spha

te d

ehyd

roge

nase

(23-

7, 7

03-1

)23

979

7960

.818

.643

.68.

321

.72

2Le

ptoI

II_sc

aff_

707_

GE

NE

_53-

deox

y-D

-ara

bino

-hep

tulo

sona

te 7

-pho

spha

te (D

AH

P) s

ynth

a22

852

4721

.77.

239.

932.

537.

62

Lept

oIII_

scaf

f_70

9_G

EN

E_2

cons

erve

d hy

poth

etic

al52

9.2

2814

.91.

663.

32

2Le

ptoI

II_sc

aff_

720_

GE

NE

_5un

ique

hyp

othe

tical

137.

927

2727

2Le

ptoI

II_sc

aff_

724_

GE

NE

_1ly

syl-t

RN

A s

ynth

etas

e39

510

810

710

.53.

52

Lept

oIII_

scaf

f_72

7_G

EN

E_1

pyrid

oxal

pho

spha

te b

iosy

nthe

tic p

rote

in p

dxA

25

5.5

3636

15.3

5.1

2Le

ptoI

II_sc

aff_

732_

GE

NE

_4(7

97-2

, 732

-4) u

niqu

e hy

poth

etic

al9.

25.

228

18.2

62

Lept

oIII_

scaf

f_73

6_G

EN

E_3

SW

F/S

NF

fam

ily h

elic

ase

(736

-3, 1

131-

1)23

6.7

9156

14.6

4.86

2Le

ptoI

II_sc

aff_

736_

GE

NE

_4co

nser

ved

hypo

thet

ical

279.

265

30.4

3.06

11.8

22

Lept

oIII_

scaf

f_74

3_G

EN

E_1

cons

erve

d hy

poth

etic

al72

816

05.

53.

932.

91.

432

Lept

oIII_

scaf

f_74

6_G

EN

E_2

glut

amyl

-tRN

A-r

educ

tase

366.

268

686.

22.

062

Lept

oIII_

scaf

f_74

6_G

EN

E_4

porp

hobi

linog

en d

eam

inas

e32

6.7

7979

5.4

1.8

2Le

ptoI

II_sc

aff_

747_

GE

NE

_3re

com

bina

se/in

tegr

ase

(81-

15, 7

47-3

)20

1023

2216

.75.

562

2Le

ptoI

II_sc

aff_

754_

GE

NE

_2po

lysa

ccha

ride

expo

rt ou

ter m

embr

ane

prot

ein

3110

2522

16.5

2.8

3.5

92

Lept

oIII_

scaf

f_76

4_G

EN

E_2

deox

yxyl

ulos

e-5-

phos

phat

e sy

ntha

se

675.

90

09.

43.

71.

81.

85.

72

Lept

oIII_

scaf

f_77

3_G

EN

E_1

phos

phat

e A

BC

tran

spor

ter p

erip

lasm

ic p

hosp

hate

-bin

ding

pr o

198.

813

1334

.526

.15.

462

2Le

ptoI

II_sc

aff_

773_

GE

NE

_5A

BC

-type

pho

spha

te tr

ansp

ort s

yste

m (1

11-2

1, 7

73-5

)28

695

9513

.43.

34.

462

Lept

oIII_

scaf

f_77

4_G

EN

E_1

ribos

omal

pro

tein

S2

(774

-1, 3

77-1

)20

1054

5441

.25.

865.

310

.62

Lept

oIII_

scaf

f_77

6_G

EN

E_3

tldD

pro

tein

, mod

ulat

or o

f DN

A g

yras

e44

5.7

109

109

22.3

6.03

8.6

2Le

ptoI

II_sc

aff_

776_

GE

NE

_6pe

ptid

e m

atur

atio

n pr

otei

n P

mbA

194.

838

3819

.46.

462

Lept

oIII_

scaf

f_78

6_G

EN

E_4

3-de

hydr

oqui

nate

deh

ydra

tase

, typ

e II

176.

733

3316

.95.

632

2Le

ptoI

II_sc

aff_

788_

GE

NE

_1rib

osom

al p

rote

in L

3 (1

088-

3, 7

88-1

)21

1045

4531

.45.

338.

938.

620

.26

26.3

22

Lept

oIII_

scaf

f_78

8_G

EN

E_2

ribos

omal

pro

tein

S10

(108

8-4,

788

-2)

1110

3232

3110

.33

22

Lept

oIII_

scaf

f_78

8_G

EN

E_3

trans

latio

n el

onga

tion

fact

or E

F-Tu

158

5858

29.9

16.6

620

.911

.16

22

Lept

oIII_

scaf

f_78

8_G

EN

E_4

trans

latio

n el

onga

tion

fact

or59

50

020

.35.

1611

5.5

5.5

2Le

ptoI

II_sc

aff_

790_

GE

NE

_1co

nser

ved

hypo

thet

ical

376.

133

10.4

3.46

22

Lept

oIII_

scaf

f_79

6_G

EN

E_1

ribos

omal

pro

tein

L1

169.

148

4842

.121

.92

2Le

ptoI

II_sc

aff_

796_

GE

NE

_2rib

osom

al p

rote

in L

10 (6

40-2

, 796

-2)

199.

722

2239

.35

22.7

22

Lept

oIII_

scaf

f_79

6_G

EN

E_3

ribos

omal

pro

tein

L12

(640

-1, 7

96-3

)13

5.1

1919

93.8

35.2

3844

67.7

67.2

22

Lept

oIII_

scaf

f_79

6_G

EN

E_4

DN

A-d

irect

ed R

NA

pol

ymer

ase,

bet

a su

buni

t23

5.7

5050

2117

18.7

9.7

122

Lept

oIII_

scaf

f_79

6_G

EN

E_5

RN

A p

olym

eras

e be

ta s

ubun

it70

6.1

1414

5.2

1.7

2Le

ptoI

II_sc

aff_

797_

GE

NE

_2un

ique

hyp

othe

tical

(797

-2, 7

32-4

)9

5.2

4122

.52

2Le

ptoI

II_sc

aff_

798_

GE

NE

_4un

ique

hyp

othe

tical

610

681

47.1

13.2

39.7

2Le

ptoI

II_sc

aff_

805_

GE

NE

_2cy

toch

rom

e c

289.

767

244.

91.

632

2Le

ptoI

II_sc

aff_

819_

GE

NE

_1rib

onuc

leos

ide-

diph

osph

ate

redu

ctas

e47

6.2

8978

28.9

6.16

10.7

5.03

2Le

ptoI

II_sc

aff_

827_

GE

NE

_2

sulfi

de:q

uino

ne o

xido

redu

ctas

e47

916

016

07.

72.

62

2Le

ptoI

II_sc

aff_

843_

GE

NE

_1un

ique

hyp

othe

tical

275

51.6

19.3

320

.26

222

2Le

ptoI

II_sc

aff_

843_

GE

NE

_2fla

vopr

otei

n re

duct

ase/

unch

arac

teriz

ed N

AD

-dep

enda

nt d

ehy d

428

126

108

43.5

8.53

20.7

313

.63

9.2

22

Lept

oIII_

scaf

f_85

3_G

EN

E_3

ribon

ucle

ase

III (1

17-1

, 853

-3)

405.

417

1715

.61.

735.

8310

.76

2Le

ptoI

II_sc

aff_

853_

GE

NE

_5un

ique

hyp

othe

tical

2310

24.6

6.26

5.8

2Le

ptoI

II_sc

aff_

867_

GE

NE

_3le

ucyl

-tRN

A s

ynth

etas

e94

6.1

00

3.2

0.66

0.4

2Le

ptoI

II_sc

aff_

87_G

EN

E_1

3ni

troge

nase

iron

pro

tein

314.

915

512

.44.

132

2Le

ptoI

II_sc

aff_

882_

GE

NE

_3A

TP-d

epen

dent

clp

pro

teas

e A

TP-b

indi

ng s

ubun

it C

lpX

(32

3-7

415.

513

413

421

.47.

112

.62

2Le

ptoI

II_sc

aff_

883_

GE

NE

_2ou

ter m

embr

ane

efflu

x pr

otei

n50

6.3

2222

29.4

1013

.43

2Le

ptoI

II_sc

aff_

904_

GE

NE

_1ch

emot

axis

pro

tein

Che

V37

5.9

6262

9.7

3.23

2Le

ptoI

II_sc

aff_

913_

GE

NE

_1ou

ter m

embr

ane

prot

ein

(sim

ilar t

o 91

9-1)

489.

956

426.

44.

260.

82

Lept

oIII_

scaf

f_91

9_G

EN

E_1

oute

r mem

bran

e pr

otei

n (s

imila

r to

913-

1)41

9.8

4533

4.7

3.13

22

Lept

oIII_

scaf

f_91

9_G

EN

E_3

uniq

ue h

ypot

hetic

al

2210

442

.522

.46

4.5

2Le

ptoI

II_sc

aff_

947_

GE

NE

_1se

nsor

y tra

nsdu

ctio

n hi

stid

ine

kina

se20

6.3

1515

15.6

5.2

2Le

ptoI

II_sc

aff_

970_

GE

NE

_2co

nser

ved

hypo

thet

ical

(sim

ilar t

o hi

ston

e-lik

e pr

otei

n/in

tegr

atio

1210

1010

20.2

6.73

2Le

ptoI

II_sc

aff_

970_

GE

NE

_42-

isop

ropy

lmal

ate

synt

hase

235

6464

4.5

1.5

2Le

ptoI

II_sc

aff_

970_

GE

NE

_5as

parta

te k

inas

e 20

549

499.

33.

12

Lept

oIII_

scaf

f_98

4_G

EN

E_2

amin

otra

nsfe

rase

s cl

ass-

I40

9.4

5353

5.3

1.76

2Le

ptoI

II_sc

aff_

984_

GE

NE

_5ph

osph

orib

osyl

form

ino-

5-am

inoi

mid

azol

e ca

rbox

amid

e rib

otid

e26

655

5513

.24.

42

Lept

oIII_

scaf

f_99

7_G

EN

E_3

prep

rote

in tr

ansl

ocas

e, S

ecA

346.

510

810

615

.27.

836.

961.

332

Lept

oIII_

scaf

f_99

9_G

EN

E_3

heav

y m

etal

effl

ux p

ump

3210

4747

9.6

3.2

2Le

ptoI

II_sc

aff_

113_

GE

NE

_21

flage

llar b

asal

-bod

y ro

d pr

otei

n Fl

gC

166

2828

10.3

2.57

2Le

ptoI

II_sc

aff_

1150

_GE

NE

_3ph

osph

ogly

cera

te d

ehyd

roge

nase

385

7977

49.9

9.8

28.0

69.

92

Lept

oIII_

scaf

f_11

77_G

EN

E_1

conj

ugal

tran

sfer

pro

tein

Tra

A62

5.4

5752

5.8

1.45

2Le

ptoI

II_sc

aff_

144_

GE

NE

_10

type

I re

stric

tion

syst

em a

deni

ne m

ethy

lase

585.

90

04.

81.

22

Lept

oIII_

scaf

f_17

9_G

EN

E_9

prot

easo

me

beta

-type

sub

unit

130

6.6

2625

41

2Le

ptoI

II_sc

aff_

192_

GE

NE

_14

uniq

ue h

ypot

hetic

al (1

81-2

, 192

-14)

114

8.2

2.73

2.05

2Le

ptoI

II_sc

aff_

375_

GE

NE

_5ef

flux

trans

porte

r, M

FP c

ompo

nent

, RN

D fa

mily

40

1031

273.

80.

952

Lept

oIII_

scaf

f_56

3_G

EN

E_2

hem

e ox

ygen

ase

286

1111

6.4

3.2

2Le

ptoI

II_sc

aff_

674_

GE

NE

_1gl

ycos

yl tr

ansf

eras

e (s

imila

r to

754-

5)43

9.7

4949

3.6

1.2

Tota

l = 2

70 (2

90 -

20 d

uplic

ates

)

2U

nass

_arc

h_sc

aff_

1018

_GE

NE

_2rib

osom

al p

rote

in L

1818

9.6

3434

24.2

6.05

22

Una

ss_a

rch_

scaf

f_10

37_G

EN

E_2

ribon

ucle

otid

e re

duct

ase

larg

e su

buni

t28

6.3

4843

32.3

9.1

24.4

22

Una

ss_a

rch_

scaf

f_10

46_G

EN

E_1

cons

erve

d hy

poth

etic

al20

8.8

338.

32.

762.

762

Una

ss_a

rch_

scaf

f_10

47_G

EN

E_3

trico

rn p

rote

ase

inte

ract

ing

fact

or/a

min

opep

tidas

e N

(sim

ilar t

o 30

6.6

2221

10.4

2.6

2U

nass

_arc

h_sc

aff_

1071

_GE

NE

_1A

DP

-hep

tose

--LP

S h

epto

syltr

ansf

eras

e II

276.

121

1233

.311

.12

2U

nass

_arc

h_sc

aff_

1071

_GE

NE

_3un

ique

hyp

othe

tical

199.

95

49.4

31.8

327

7.6

22

Una

ss_a

rch_

scaf

f_10

88_G

EN

E_1

ribos

omal

pro

tein

S19

910

2626

43.2

32.1

315

.23

37.8

628

.42

2U

nass

_arc

h_sc

aff_

1088

_GE

NE

_2rib

osom

al p

rote

in L

215

1145

4332

.612

.118

.93

8.06

16.3

312

.12

2U

nass

_arc

h_sc

aff_

1088

_GE

NE

_3rib

osom

al p

rote

in L

3 (7

88-1

, 108

8-3)

2110

4545

31.4

5.33

8.93

8.6

20.2

626

.32

2U

nass

_arc

h_sc

aff_

1088

_GE

NE

_4rib

osom

al p

rote

in S

10 (7

88-2

, 108

8-4)

119.

832

3231

10.3

32

Una

ss_a

rch_

scaf

f_11

03_G

EN

E_1

hem

e-he

mop

exin

util

izat

ion

prot

ein

B28

6.9

1715

15.9

5.3

2U

nass

_arc

h_sc

aff_

207_

GE

NE

_6ty

pe I

rest

rictio

n en

zym

e (2

07-6

, 476

-6)

114

6.1

010

93.

41.

132

Una

ss_a

rch_

scaf

f_31

9_G

EN

E_1

cons

erve

d hy

poth

etic

al11

9.2

1014

144.

664.

6614

2U

nass

_arc

h_sc

aff_

319_

GE

NE

_6co

nser

ved

hypo

thet

ical

788

653.

11.

032

Una

ss_a

rch_

scaf

f_32

9_G

EN

E_2

cons

erve

d hy

poth

etic

al (6

46-3

, 329

-2)

1210

3710

.72.

672

2U

nass

_arc

h_sc

aff_

347_

GE

NE

_4ty

pe II

rest

rictio

n en

zym

e, m

ethy

lase

sub

unit

140

6.3

4946

4.3

0.93

0.93

2U

nass

_arc

h_sc

aff_

406_

GE

NE

_5A

BC

tran

spor

ter A

TP-b

indi

ng p

rote

in35

8.8

4942

2.6

0.86

2U

nass

_arc

h_sc

aff_

406_

GE

NE

_6tra

nspo

sase

10

6.9

1313

20.7

13.8

10.3

52

Una

ss_a

rch_

scaf

f_40

6_G

EN

E_7

inte

gras

e/re

com

bina

se (4

06-7

, 954

-4)

329.

336

1510

.32.

572

Una

ss_a

rch_

scaf

f_42

4_G

EN

E_9

trans

posa

se

348.

473

734.

41.

11.

12

Una

ss_a

rch_

scaf

f_43

6_G

EN

E_3

(sim

ilar t

o 10

39-4

) the

rmop

sin

121

4.4

9732

3.7

1.23

1.23

2U

nass

_arc

h_sc

aff_

459_

GE

NE

_7D

NA

inve

rtase

/reso

lvas

e20

1081

8110

.63.

532

Una

ss_a

rch_

scaf

f_47

4_G

EN

E_1

trans

posa

se

439.

875

758.

68.

62

Una

ss_a

rch_

scaf

f_50

5_G

EN

E_6

uniq

ue h

ypot

hetic

al (A

TPas

e-lik

e) (8

33-1

, 505

-6)

97.

99

31.6

10.5

32

Una

ss_a

rch_

scaf

f_51

6_G

EN

E_2

uniq

ue h

ypot

hetic

al (s

imila

r to

O-li

nked

Glc

NA

c tra

nsfe

rase

s)59

4.6

111

85.

81.

932

Una

ss_a

rch_

scaf

f_51

6_G

EN

E_4

cons

erve

d hy

poth

etic

al (2

47-9

, sim

ilar t

o 31

0-4)

(sim

ilar t

o re

str

419.

943

2.8

0.93

2U

nass

_arc

h_sc

aff_

574_

GE

NE

_3ty

pe II

rest

rictio

n en

zym

e, m

ethy

lase

sub

unit

140

6.9

5151

1.5

0.5

22

Una

ss_a

rch_

scaf

f_61

0_G

EN

E_2

inos

ine-

5'-m

onop

hosp

hate

deh

ydro

gena

se (3

37-2

, 610

-2)

155.

215

1054

.714

.83

16.7

632

.33

8.8

2U

nass

_arc

h_sc

aff_

610_

GE

NE

_4rib

osom

al p

rote

in L

1721

1128

2727

.520

.96

23.6

22

Una

ss_a

rch_

scaf

f_61

0_G

EN

E_5

DN

A-d

irect

ed R

NA

pol

ymer

ase,

alp

ha s

ubun

it35

5.3

7676

373

18.3

34.

862

2U

nass

_arc

h_sc

aff_

610_

GE

NE

_7rib

osom

al p

rote

in S

119.

510

2020

103.

3310

6.66

3.33

2U

nass

_arc

h_sc

aff_

621_

GE

NE

_4co

nser

ved

hypo

thet

ical

(11-

34, 6

21-4

)26

8.8

995

1.66

2U

nass

_arc

h_sc

aff_

693_

GE

NE

_1tra

nspo

sase

29

9.3

132

189.

93.

32

2U

nass

_arc

h_sc

aff_

748_

GE

NE

_4D

EX

X-b

ox A

TPas

e57

8.4

8685

50.

631.

264.

82

Una

ss_a

rch_

scaf

f_76

3_G

EN

E_1

ATP

-dep

ende

nt p

rote

ase

La (3

73-3

, 763

-1)

315.

711

511

49.

83.

265.

42

Una

ss_a

rch_

scaf

f_76

3_G

EN

E_2

cons

erve

d hy

poth

etic

al (3

73-2

, 763

-2)

248.

629

10.9

7.26

2U

nass

_arc

h_sc

aff_

833_

GE

NE

_1un

ique

hyp

othe

tical

(ATP

ase-

like)

(505

-6, 8

33-1

)9

7.9

931

.610

.53

2U

nass

_arc

h_sc

aff_

899_

GE

NE

_4D

NA

prim

ase

smal

l sub

unit

(sim

ilar t

o 1-

107)

275.

910

038

8.7

2.17

2U

nass

_arc

h_sc

aff_

948_

GE

NE

_1ol

igop

eptid

e tra

nspo

rt A

TP-b

indi

ng p

rote

in20

966

65.

55.

52

Una

ss_a

rch_

scaf

f_95

4_G

EN

E_4

uniq

ue h

ypot

hetic

al (4

06-7

, 954

-4)

157.

98

15.7

3.92

2U

nass

_arc

h_sc

aff_

963_

GE

NE

_1gl

ycos

yl tr

ansf

eras

e63

8.6

1919

38.7

15.5

620

.53

2.83

2U

nass

_arc

h_sc

aff_

963_

GE

NE

_2gl

ycos

yl tr

ansf

eras

e29

5.4

6764

22.4

3.86

3.6

2U

nass

_arc

h_sc

aff_

967_

GE

NE

_1su

gar A

BC

tran

spor

ter,

ATP

-bin

ding

pro

tein

(967

-1, 9

-29)

254.

811

692

11.4

3.8

Tota

l = 3

0 (4

3 - 1

3 du

plic

ates

)

22

Una

ss_b

act_

scaf

f_10

02_G

EN

E_4

uniq

ue h

ypot

hetic

al (1

002-

4, 3

2-4)

265.

464

.29.

1614

.83

5.66

22

Una

ss_b

act_

scaf

f_10

06_G

EN

E_1

flavo

prot

ein/

cdp-

abeq

uose

syn

thas

e21

5.1

5039

45.4

26.3

1128

.46

18.4

2U

nass

_bac

t_sc

aff_

1006

_GE

NE

_3tw

o-co

mpo

nent

resp

onse

regu

lato

r/GG

DE

F do

mai

n pr

otei

n40

5.8

5742

21.2

12.0

32

2U

nass

_bac

t_sc

aff_

1042

_GE

NE

_1co

nser

ved

hypo

thet

ical

(sim

ilar t

o 10

42-1

, 173

-16,

261

-9, 2

65-

155.

223

80.9

37.6

326

.43

64.6

345

2U

nass

_bac

t_sc

aff_

1042

_GE

NE

_4co

nser

ved

hypo

thet

ical

(104

2-4,

219

-3)

108.

311

28.9

9.63

22

Una

ss_b

act_

scaf

f_10

42_G

EN

E_6

shuf

flon-

spec

ific

reco

mbi

nase

(104

2-6,

219

-5)

119.

224

1520

.26.

732

2U

nass

_bac

t_sc

aff_

1045

_GE

NE

_1A

TP-d

epen

dent

RN

A h

elic

ase

Rhl

E (2

88-1

, 104

5-1)

339.

862

6260

.213

.46

26.0

616

.03

38.5

2U

nass

_bac

t_sc

aff_

1052

_GE

NE

_3m

rr re

stric

tion

syst

em p

rote

in34

5.9

9191

29.8

2.76

8.36

7.73

22

Una

ss_b

act_

scaf

f_10

56_G

EN

E_1

antir

estri

ctio

n pr

otei

n (5

33-4

, 105

6-1)

356.

236

3511

.23.

733.

732

Una

ss_b

act_

scaf

f_10

57_G

EN

E_2

aden

ine

DN

A m

ethy

ltran

sfer

ase

329.

336

115.

81.

932

Una

ss_b

act_

scaf

f_10

78_G

EN

E_2

uniq

ue h

ypot

hetic

al (1

078-

2, 8

15-5

)29

5.5

720

.23.

54.

768

2U

nass

_bac

t_sc

aff_

1093

_GE

NE

_2D

NA

or R

NA

hel

icas

e of

sup

erfa

mily

II58

5.6

147

134

3.8

1.26

2U

nass

_bac

t_sc

aff_

1102

_GE

NE

_1D

NA

or R

NA

hel

icas

e of

sup

erfa

mily

II (2

7-47

, 110

2-1)

174.

831

2930

.110

22

Una

ss_b

act_

scaf

f_11

07_G

EN

E_1

trans

latio

n in

itiat

ion

fact

or IF

-3 (1

107-

1, 3

-43)

66.

116

1382

.556

.747

.36

71.9

71.9

71.9

22

Una

ss_b

act_

scaf

f_11

07_G

EN

E_2

thre

onyl

tRN

A s

ynth

etas

e (3

-44,

110

7-2)

685.

90

036

.212

.921

.87.

762

Una

ss_b

act_

scaf

f_11

19_G

EN

E_1

mob

iliza

tion

prot

ein

A (s

imila

r to

811-

2)18

9.9

2222

10.1

3.36

10.1

2U

nass

_bac

t_sc

aff_

1119

_GE

NE

_3co

nser

ved

hypo

thet

ical

20

9.7

4216

5.33

2U

nass

_bac

t_sc

aff_

1131

_GE

NE

_1S

WF/

SN

F fa

mily

hel

icas

e (7

36-3

, 113

1-1)

248

9559

13.9

4.63

22

Una

ss_b

act_

scaf

f_11

31_G

EN

E_3

uniq

ue h

ypot

hetic

al (1

131-

3, 5

11-2

)18

9.9

50.3

38.5

626

.347

.13

37.0

343

.92

Una

ss_b

act_

scaf

f_11

36_G

EN

E_3

Gsp

D, g

ener

al s

ecre

tory

pro

tein

(186

-4, 1

136-

3)28

8.6

3636

34.7

25.3

68.

332

Una

ss_b

act_

scaf

f_11

41_G

EN

E_4

quin

opro

tein

deh

ydro

gena

se/o

uter

mem

bran

e pr

otei

n (9

20-3

, 120

1049

4961

.346

.96

22

Una

ss_b

act_

scaf

f_11

48_G

EN

E_1

ATP

-dep

ende

nt C

lp p

rote

ase,

ATP

-bin

ding

sub

unit

Clp

C30

5.3

7874

23.1

13.3

32

2U

nass

_bac

t_sc

aff_

1152

_GE

NE

_1un

ique

hyp

othe

tical

1110

39.2

26.1

32

2U

nass

_bac

t_sc

aff_

1152

_GE

NE

_4un

ique

hyp

othe

tical

274.

536

.728

.23

4.63

2U

nass

_bac

t_sc

aff_

235_

GE

NE

_2ca

tion

efflu

x sy

stem

pro

tein

czc

A92

8.7

017

93

12

Una

ss_b

act_

scaf

f_23

5_G

EN

E_4

pept

ide-

chai

n-re

leas

e fa

ctor

360

5.9

162

162

5.4

2.5

2U

nass

_bac

t_sc

aff_

235_

GE

NE

_5re

com

bina

tion

prot

ein

Rec

R18

5.2

3939

12.2

4.06

22

Una

ss_b

act_

scaf

f_33

7_G

EN

E_2

inos

ine-

5'-m

onop

hosp

hate

deh

ydro

gena

se (3

37-2

, 610

-2)

155.

215

1052

.113

.46

1936

.69.

92

Una

ss_b

act_

scaf

f_36

3_G

EN

E_7

uniq

ue h

ypot

hetic

al13

5.9

13.3

4.43

2U

nass

_bac

t_sc

aff_

458_

GE

NE

_11

dihy

drol

ipoa

mid

e de

hydr

ogen

ase

(59-

4, 4

58-1

1)27

6.6

4946

20.6

6.8

32

2U

nass

_bac

t_sc

aff_

622_

GE

NE

_2rib

osom

al p

rote

in S

915

1130

2960

.711

.86

18.7

63.

4626

.43

36.3

2U

nass

_bac

t_sc

aff_

622_

GE

NE

_350

S ri

boso

mal

pro

tein

L13

1710

3838

477.

1640

.92

Una

ss_b

act_

scaf

f_62

2_G

EN

E_4

Fe-S

oxi

dore

duct

ase/

met

hyltr

ansf

eras

e63

5.8

5757

4.7

2.7

1.13

1.13

22

Una

ss_b

act_

scaf

f_64

7_G

EN

E_3

sign

al re

cogn

ition

par

ticle

(114

0-1,

647

-3)

499.

410

510

35.

43.

465.

22.

562

2U

nass

_bac

t_sc

aff_

647_

GE

NE

_4In

tegr

atio

n ho

st fa

ctor

bet

a-su

buni

t/his

tone

-like

DN

A-b

indi

ng p

1111

1111

21.9

7.3

5.2

2U

nass

_bac

t_sc

aff_

647_

GE

NE

_6rib

osom

al p

rote

in S

134

6.5

131

897.

94.

061.

862

Una

ss_b

act_

scaf

f_66

7_G

EN

E_1

cons

erve

d hy

poth

etic

al22

5.1

4315

.85.

262

2U

nass

_bac

t_sc

aff_

753_

GE

NE

_5un

ique

hyp

othe

tical

(374

-2, 7

53-5

)8

8.1

79.5

29.2

17.3

670

.33

52.1

2U

nass

_bac

t_sc

aff_

760_

GE

NE

_4un

ique

hyp

othe

tical

339.

713

.18.

732

Una

ss_b

act_

scaf

f_76

6_G

EN

E_3

Trw

B p

lasm

id p

rote

in47

7.1

4545

4.5

1.5

22

Una

ss_b

act_

scaf

f_76

8_G

EN

E_4

uniq

ue h

ypot

hetic

al (7

68-4

, 47

8-6)

115.

669

.149

.83

58.7

658

.76

48.5

22

Una

ss_b

act_

scaf

f_77

1_G

EN

E_2

uniq

ue h

ypot

hetic

al20

9.6

72.9

5838

.96

56.6

644

.46

24.3

2U

nass

_bac

t_sc

aff_

775_

GE

NE

_4N

-ace

tylm

uram

oyl-L

-ala

nine

am

idas

e, fa

mily

3 (7

75-4

, 167

-10 )

2010

2323

7.5

2.5

2U

nass

_bac

t_sc

aff_

820_

GE

NE

_1su

lfide

-qui

none

redu

ctas

e (8

20-1

, 41-

7)46

8.6

159

157

32.8

3.7

2.36

8.73

12.3

2U

nass

_bac

t_sc

aff_

829_

GE

NE

_1un

ique

hyp

othe

tical

(sim

ilar t

o m

obili

zatio

n pr

otei

n M

obE

) (23

225

8.9

513

4.33

2U

nass

_bac

t_sc

aff_

829_

GE

NE

_5un

ique

hyp

othe

tical

84.

373

.141

.92

Una

ss_b

act_

scaf

f_87

5_G

EN

E_3

uniq

ue h

ypot

hetic

al21

9.9

15.5

5.16

2U

nass

_bac

t_sc

aff_

903_

GE

NE

_5un

ique

hyp

othe

tical

(sim

ilar t

o A

BC

tran

spor

ter s

ubst

rate

-bin

din

1310

66

378.

437

8.96

26.9

22

Una

ss_b

act_

scaf

f_92

0_G

EN

E_3

quin

opro

tein

deh

ydro

gena

se/o

uter

mem

bran

e pr

otei

n (s

imila

r T47

1011

535

39.7

30.5

32

2U

nass

_bac

t_sc

aff_

936_

GE

NE

_1R

NA

pol

ymer

ase

sigm

a fa

ctor

Rpo

D (2

24-4

, 936

-1)

224

2828

58.4

39.4

42.1

65.

232

Una

ss_b

act_

scaf

f_93

6_G

EN

E_2

uniq

ue h

ypot

hetic

al (2

24-3

, 936

-3, 9

36-2

)13

6.6

14.3

4.76

2U

nass

_bac

t_sc

aff_

936_

GE

NE

_3D

NA

prim

ase

(936

-3, 2

24-3

, 936

-2)

395.

636

3628

.22.

963.

732.

662

Una

ss_b

act_

scaf

f_94

1_G

EN

E_3

cons

erve

d hy

poth

etic

al (f

lavo

hem

opro

tein

-like

)13

5.5

168

38.9

20.9

32

Una

ss_b

act_

scaf

f_95

7_G

EN

E_2

pyru

vate

:ferr

edox

in o

xido

redu

ctas

e de

lta s

ubun

it21

6.5

4645

11.7

3.9

11.7

22

Una

ss_b

act_

scaf

f_95

9_G

EN

E_1

cons

erve

d hy

poth

etic

al29

9.3

204.

41.

462.

932

Una

ss_b

act_

scaf

f_96

9_G

EN

E_3

trans

porte

r, E

amA

fam

ily29

1011

116

4

2U

nass

_bac

t_sc

aff_

977_

GE

NE

_2co

nser

ved

hypo

thet

ical

(412

-4, 9

77-2

)16

6.7

3425

.28.

42

2U

nass

_bac

t_sc

aff_

989_

GE

NE

_1py

ruva

te:fe

rred

oxin

oxi

dore

duct

ase

delta

sub

unit

(979

-1, 9

89-1

218.

751

4947

.711

.413

.317

.124

.92

Una

ss_b

act_

scaf

f_11

40_G

EN

E_2

ribos

omal

pro

tein

S16

(647

-2, 1

140-

2)9

1118

1730

.92.

1510

.32

Una

ss_b

act_

scaf

f_64

7_G

EN

E_2

ribos

omal

pro

tein

S16

(647

-2, 1

140-

2)9

1118

1730

.92.

1510

.32

Una

ss_b

act_

scaf

f_89

4_G

EN

E_3

thre

onyl

-tRN

A s

ynth

etas

e47

5.5

154

154

4.9

1.22

Tota

l = 3

6 (6

1 - 2

5 du

plic

ates

)

Tota

l abo

ve =

214

5 (2

003

+ 14

2 du

plic

ates

/spl

it ge

nes)

Plu

s 30

dis

cove

red

in o

verla

ppin

g or

alte

rnat

ive

read

ing

fram

es (s

ee T

able

S2)

Gra

nd to

tal =

2,0

33

Table S2 of Ram et al. *hypo unique=unique hypothetical, c hypo=conserved hypothetical

Lepto II scaffold & gene Notes hypo type OP annotation, detects (cream), operons with novel proteins (red ) COG family LeptoII-1: LeptoII_scaffold_2_GENE_1 hypo unique* hypo unique

LeptoII_scaffold_2_GENE_2 c hypo* c hypoLeptoII_scaffold_2_GENE_3 c hypo c hypoLeptoII_scaffold_2_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_5 hypo unique hypo unique, possible chemotaxis proteinLeptoII_scaffold_2_GENE_6 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_2_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_8 T1 transposase (one of two copies) transposaseLeptoII_scaffold_2_GENE_9 c hypo c hypoLeptoII_scaffold_2_GENE_10 proline dehydrogenase [Amino acid transport and metabolism]LeptoII_scaffold_2_GENE_11 DNA/RNA helicase, Snf2 [Transcription]LeptoII_scaffold_2_GENE_12 nitrogen regulator protein PII [Amino acid transport and metabolism]LeptoII_scaffold_2_GENE_13 ammonia transporter [Inorganic ion transport and metabolism]LeptoII_scaffold_2_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_15 Lex A transcriptional repressor [Transcription / Signal transduction mechanisms]LeptoII_scaffold_2_GENE_16 NADH dehydrogenase, subunit N [Energy production and conversion]LeptoII_scaffold_2_GENE_17 NADH dehydrogenase, subunit M [Energy production and conversion]LeptoII_scaffold_2_GENE_18 NADH dehydrogenase, subunit L [Energy production and conversion]LeptoII_scaffold_2_GENE_19 NADH degydrogenase, subunit K [Energy production and conversion]LeptoII_scaffold_2_GENE_20 NADH dehydrogenase, subunit J [Energy production and conversion]LeptoII_scaffold_2_GENE_21 NADH dehydrogenase, subunit I [Energy production and conversion]LeptoII_scaffold_2_GENE_22 NADH dehydrogenase, subunit H [Energy production and conversion]LeptoII_scaffold_2_GENE_23 NADH dehydrogenase, subunit G [Energy production and conversion]LeptoII_scaffold_2_GENE_24 NADH dehydrogenase, subunit F [Energy production and conversion]LeptoII_scaffold_2_GENE_25 NADH dehydrogenase, subunit E [Energy production and conversion]LeptoII_scaffold_2_GENE_26 NADH dehydrogenase, subunit D [Energy production and conversion]LeptoII_scaffold_2_GENE_27 NADH dehydrogenase, subunit C [Energy production and conversion]LeptoII_scaffold_2_GENE_28 NADH dehydrogenase, subunit B [Energy production and conversion]LeptoII_scaffold_2_GENE_29 NADH dehydrogenase, subunit A [Energy production and conversion]LeptoII_scaffold_2_GENE_30 preprotein translocase [Intracellular trafficking and secretion]LeptoII_scaffold_2_GENE_31 membrane-bound metallopeptidase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_2_GENE_32 periplasmic divalent cation tolerance protein, chain A [Inorganic ion transport and metabolism]LeptoII_scaffold_2_GENE_33 UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane / Carb. trans. andLeptoII_scaffold_2_GENE_34 hemolysin/rRNA methylase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_2_GENE_35 deoxyxylulose-5-phosphate synthase [Coenzyme metabolism / Lipid metabolism]LeptoII_scaffold_2_GENE_36 geranylgeranyl phosphate synthase [Coenzyme metabolism]LeptoII_scaffold_2_GENE_37 hypo unique hypo unique, possible exonuclease VIILeptoII_scaffold_2_GENE_38 exodeoxyribonuclease VII large subunit [DNA replication, recombination, and repair]LeptoII_scaffold_2_GENE_39 c hypo c hypoLeptoII_scaffold_2_GENE_40 hydrolase (HAD superfamily) [General function prediction only]LeptoII_scaffold_2_GENE_41 AAA family ATPase related to helicase subunit [DNA replication, recombination, and repair]LeptoII_scaffold_2_GENE_42 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_43 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_44 soluble lytic transglycosylase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_2_GENE_45 TonB-like protein [Lipid metabolism ]LeptoII_scaffold_2_GENE_46 dimethyladenosine transferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_2_GENE_47 Zn-dependent hydrolase [General function prediction only]LeptoII_scaffold_2_GENE_48 cell division (DNA translocation) protein, FtsK [Cell divison and chromosome partitioning]LeptoII_scaffold_2_GENE_49 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_50 excinuclease ABC, subunit A [DNA replication, recombination, and repair]LeptoII_scaffold_2_GENE_51 cation efflux system protein [Inorganic ion transport and metabolism]LeptoII_scaffold_2_GENE_52 pyridoxal phosphate biosynthesis [Coenzyme metabolism]LeptoII_scaffold_2_GENE_53 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_2_GENE_54 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_55 DNA repair exonuclease [DNA replication, recombination, and repair]LeptoII_scaffold_2_GENE_56 ABC transporter, periplasmic comp. Inv. in resist. to org. solvents [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_2_GENE_57 ABC transporter, ATP-binding protein inv. in resist. to org. solvent [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_2_GENE_58 ABC transporter, permease protein involved in resistance to organic so [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_2_GENE_59 Endonuclease IV [DNA replication, recombination, and repair]LeptoII_scaffold_2_GENE_60 UDP-glucose-4-epimerase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_2_GENE_61 signal transduction histidine kinase [Signal transduction mechanisms]LeptoII_scaffold_2_GENE_62 phosphate regulon transcription regulator, PhoB [Transcription]LeptoII_scaffold_2_GENE_63 metal-dependent protease of the PAD1/JAB1 superfamily [General function prediction only]LeptoII_scaffold_2_GENE_64 molbdopterin biosynthesis protein MoeB [Coenzyme metabolism]LeptoII_scaffold_2_GENE_65 hypo unique hypo unique, possible ferredoxinLeptoII_scaffold_2_GENE_66 c hypo c hypo, possible molybdopterin converting factor

LeptoII_scaffold_2_GENE_67 threonine synthase [Amino acid transport and metabolism]LeptoII_scaffold_2_GENE_68 thiamine biosynthesis protein ThiF [Coenzyme metabolism]LeptoII_scaffold_2_GENE_69 cysteine synthase [Amino acid transport and metabolism]LeptoII_scaffold_2_GENE_70 hypo unique hypo unique (ThiS-like)LeptoII_scaffold_2_GENE_71 S-adenosylhomocyteine hydrolase [Coenzyme metabolism]LeptoII_scaffold_2_GENE_72 S-adenosinemethionine synthase [Coenzyme metabolism]LeptoII_scaffold_2_GENE_73 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_74a hypo unique hypo unique found overlapping 2-74LeptoII_scaffold_2_GENE_74b 2-73 = tRNA Ala 2-74 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_75 oxygen-independent coporphyrinogen II [Coenzyme metabolism]LeptoII_scaffold_2_GENE_76 eroporphyrinogen decarboxylase [Coenzyme metabolism]LeptoII_scaffold_2_GENE_77 cobalt chetalase, cbiX [Coenzyme metabolism]LeptoII_scaffold_2_GENE_78 c hypo c hypo LeptoII_scaffold_2_GENE_79 c hypo c hypoLeptoII_scaffold_2_GENE_80 ceramide glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_2_GENE_81 Fe-S oxidoreductase [Energy production and conversion]LeptoII_scaffold_2_GENE_82 penicillin tolerance protein, LytB [Lipid metabolism ]LeptoII_scaffold_2_GENE_83 dihydroflavonol 4-reductase [Cell envelope biogenesis, outer membrane / Carb. trans. andLeptoII_scaffold_2_GENE_84 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_85 c hypo c hypoLeptoII_scaffold_2_GENE_86 hypo unique hypo unique LeptoII_scaffold_2_GENE_87 squalene-hopene cyclase [Lipid metabolism]LeptoII_scaffold_2_GENE_88 T2 transposase (single) transposaseLeptoII_scaffold_2_GENE_89 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_90 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_91a hypo unique hypo unique found overlapping 2-91LeptoII_scaffold_2_GENE_91b hypo unique hypo uniqueLeptoII_scaffold_2_GENE_92 c hypo c hypo - suspect cell division relatedLeptoII_scaffold_2_GENE_93 pyrroline-5-carboxylate reductase [Amino acid transport and metabolism]LeptoII_scaffold_2_GENE_94 potassium uptake protein [Inorganic ion transport and metabolism]LeptoII_scaffold_2_GENE_95 hypo unique hypo unique found in alternative reading frameLeptoII_scaffold_2_GENE_96 tubulin-like, FtsZ [Cell divison and chromosome partitioning]LeptoII_scaffold_2_GENE_97 cell division protein, FtsA [Cell divison and chromosome partitioning]LeptoII_scaffold_2_GENE_98 hypo unique hypo unique found in alternative reading frameLeptoII_scaffold_2_GENE_99 D-ala D-ala ligase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_2_GENE_100 UDP-N-acetylenolpyruvoylglucosamine reductase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_2_GENE_101 UDP-N-acetymuramate dehyddrogenase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_2_GENE_102 UDP-N-acetylglucosamine-N-acetylmuramyl-(penta… [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_2_GENE_103 cell division protein FtsW [Cell divison and chromosome partitioning]LeptoII_scaffold_2_GENE_104 UDP-N-acetylmuramoylalanine-D-glutamate ligase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_2_GENE_105 phospho-N-acetylmuramoyl-pentapeptide transferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_2_GENE_106 UDP-N-acetylmuramoylalanyl-D-glutamyl-2,6-diaminopimelate-D-alany [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_2_GENE_107 UDP-N-acetylmuramoylalanyl-D-glutamate-2,6-diamino… [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_2_GENE_108 cell division protein FtsI [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_2_GENE_109 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_110 S-adenosyl-methyltransferase MraW [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_2_GENE_111 c hypo c hypoLeptoII_scaffold_2_GENE_112 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_113 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_114 peroxiredoxin - antioxidant protein [Defense]LeptoII_scaffold_2_GENE_115 succinyl-coA synthetase [Energy production and conversion]LeptoII_scaffold_2_GENE_116 succinyl-coA synthetase [Energy production and conversion]LeptoII_scaffold_2_GENE_117 succinate dehydrogenase [Energy production and conversion]LeptoII_scaffold_2_GENE_118 c hypo c hypo (like CO dehydrogenase/acetyl-CoA synthase)LeptoII_scaffold_2_GENE_119 c hypo c hypoLeptoII_scaffold_2_GENE_120 citrate synthase [Energy production and conversion]LeptoII_scaffold_2_GENE_121 aconitase (abundant membrane protein) [Energy production and conversion]LeptoII_scaffold_2_GENE_122 hypo unique hypo uniqueLeptoII_scaffold_2_GENE_123 succinyl co-A ligase, AbMem protein [Energy production and conversion]LeptoII_scaffold_2_GENE_124 succinyl-coA ligase [Energy production and conversion]LeptoII_scaffold_2_GENE_125 T3 transposase transposaseLeptoII_scaffold_2_GENE_126 2-126 = tRNA Glu =2-127 succinyl-coA synthase [Energy production and conversion]LeptoII_scaffold_2_GENE_127 integrase (fragment, no domain) integrase (partial) [DNA replication, recombination, and repair]LeptoII_scaffold_2_GENE_128 T3 2-127=tRNA=Glu 2-128 transposase transposaseLeptoII_scaffold_7_GENE_1 7-0=tRNA Glu=7-1 hypo unique hypo uniqueLeptoII_scaffold_7_GENE_2 sensory box protein/GGDEF domain protein [Signal transduction mechanisms]LeptoII_scaffold_7_GENE_3 cytoplasmic phosphatase [Signal transduction mechanisms]LeptoII_scaffold_7_GENE_4 sigma54-dependant DNA binding response regulator [Transcription / Signal transduction mechanisms]LeptoII_scaffold_7_GENE_5 UDP-glucose 4-epimerase [Cell envelope biogenesis, outer membrane / Carb. trans. andLeptoII_scaffold_7_GENE_6 hypo unique hypo unique

LeptoII_scaffold_7_GENE_7 UDP-N-acetyl-D-mannosaminuronate dehydrogenase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_8 Glucosamine-fructose-6-phosphate aminotransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_9 sigma54-dependant transcriptional regulator [Transcription]LeptoII_scaffold_7_GENE_10 adenylate/guanylate cyclase [Signal transduction mechanisms]LeptoII_scaffold_7_GENE_11 nucleotide sugar epimerase [Cell envelope biogenesis, outer membrane / Carb. trans. andLeptoII_scaffold_7_GENE_12 UDP-galactopyranose mutase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_13 site-specific DNA methyltransferase [DNA replication, recombination, and repair]LeptoII_scaffold_7_GENE_14 hypo unique hypo unique found in alternative reading frameLeptoII_scaffold_7_GENE_15 sensory box protein/GGDEF domain protein [Signal transduction mechanisms]LeptoII_scaffold_7_GENE_16 small conductance mechanosensitive ion channel [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_17 transcriptional regulator [Transcription]LeptoII_scaffold_7_GENE_18 mercuric iron reductase, MerA [Defense]LeptoII_scaffold_7_GENE_19 hypo unique hypo uniqueLeptoII_scaffold_7_GENE_20 RNA polymerase sigma factor [Transcription]LeptoII_scaffold_7_GENE_21 c hypo c hypoLeptoII_scaffold_7_GENE_22 hypo unique hypo uniqueLeptoII_scaffold_7_GENE_23 hypo unique hypo uniqueLeptoII_scaffold_7_GENE_24 hypo c hypoLeptoII_scaffold_7_GENE_25 c hypo c hypoLeptoII_scaffold_7_GENE_26 ATPase [General function prediction only]LeptoII_scaffold_7_GENE_27 sugar transferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_28 polysaccharide transport [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_29 c hypo c hypo (MmcA-like)LeptoII_scaffold_7_GENE_30 polysaccharide deacetylase [Carbohyhrate transport and metabolism]LeptoII_scaffold_7_GENE_31 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_32 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_33 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_34 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_35 c hypo c hypo (possible secreted polysaccharide polymerase)LeptoII_scaffold_7_GENE_36 hypo unique hypo uniqueLeptoII_scaffold_7_GENE_37 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_38 rhamnosyl transferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_39 sensor histidine kinase [Signal transduction mechanisms]LeptoII_scaffold_7_GENE_40 sensor histidine kinase [Signal transduction mechanisms]LeptoII_scaffold_7_GENE_41 UTP-glucose-1-phosphate uridylyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_42 c hypo c hypoLeptoII_scaffold_7_GENE_43 c hypo c hypoLeptoII_scaffold_7_GENE_44 sigma54-dependant DNA binding response regulator [Signal transduction mechanisms]LeptoII_scaffold_7_GENE_45 hypo unique hypo uniqueLeptoII_scaffold_7_GENE_46 c hypo c hypoLeptoII_scaffold_7_GENE_47 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_48 sugar transferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_49 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_50 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_51 SAM-dependent methyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_52 chitinase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_7_GENE_53 ABC transporter/antibiotic exporter, ATP binding protein [Defense mechanisms]LeptoII_scaffold_7_GENE_54 c hypo c hypoLeptoII_scaffold_7_GENE_55 hypo unique hypo uniqueLeptoII_scaffold_7_GENE_56 c hypo c hypoLeptoII_scaffold_7_GENE_57 c hypo c hypo (faint similarity to glucoamylase I)LeptoII_scaffold_7_GENE_58 c hypo c hypoLeptoII_scaffold_7_GENE_59 hypo unique hypo uniqueLeptoII_scaffold_7_GENE_60 hypo unique hypo uniqueLeptoII_scaffold_7_GENE_61 two component response regulator [Transcription]LeptoII_scaffold_7_GENE_62 signal transduction histidine kinase [Signal transduction mechanisms]LeptoII_scaffold_206_GENE_1 regulator of RpfF regulator of pathogenicity factors, RpfF [Lipid metabolism]LeptoII_scaffold_206_GENE_2 sensory box/GGDEF family protein [Signal transduction mechanisms]LeptoII_scaffold_206_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_206_GENE_4 alcohol dehydrogenase [General function prediction only]LeptoII_scaffold_206_GENE_5 glycosidase [Carbohyhrate transport and metabolism]LeptoII_scaffold_206_GENE_6 glycosidase [Carbohyhrate transport and metabolism]LeptoII_scaffold_206_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_206_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_213_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_213_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_213_GENE_3 two component response regulator [Signal transduction mechanisms]LeptoII_scaffold_213_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_213_GENE_5 sensory box/GGDEF family protein [Signal transduction mechanisms]LeptoII_scaffold_213_GENE_6 fatty acid desaturase [Lipid metabolism]

LeptoII_scaffold_213_GENE_7 trehalose synthase [Carbohyhrate transport and metabolism]LeptoII_scaffold_213_GENE_8 trehalose synthase [Carbohyhrate transport and metabolism]LeptoII_scaffold_86_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_86_GENE_2 maltoligosyltrehalose synthase [Carbohyhrate transport and metabolism]LeptoII_scaffold_86_GENE_3 alpha amylase [Carbohyhrate transport and metabolism]LeptoII_scaffold_86_GENE_4 glutamate decarboxylase isozyme I [Amino acid transport and metabolism]LeptoII_scaffold_86_GENE_5 phosphohistidine phosphatase [Signal transduction mechanisms]LeptoII_scaffold_86_GENE_6 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_86_GENE_7 c hypo c hypoLeptoII_scaffold_86_GENE_8 major facilitator superfamily transporter [General function prediction only]LeptoII_scaffold_86_GENE_9 dTDP-4-dehydrorhamnose 3,5-epimerase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_86_GENE_10 glucose-1-phosphate thymidyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_86_GENE_11 dTDP-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_86_GENE_12 aconitase [Amino acid transport and metabolism]LeptoII_scaffold_86_GENE_13 isopropylmalate dehydrogenase [Amino acid transport and metabolism]LeptoII_scaffold_86_GENE_14 86-14=tRNA Lys=86-15 permease [General function prediction only]LeptoII_scaffold_86_GENE_15 small recombinase fragment small recombinase fragment (no domain) [DNA replication, recombination, and repair]LeptoII_scaffold_86_GENE_16 hypo unique hypo uniqueLeptoII_scaffold_86_GENE_17 hypo unique hypo uniqueLeptoII_scaffold_86_GENE_18 c hypo c hypoLeptoII_scaffold_287_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_287_GENE_2 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_287_GENE_3 peptide methionine sulfoxide reductase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_287_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_287_GENE_5 protoporphyrinogen oxidase [Coenzyme metabolism]LeptoII_scaffold_287_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_287_GENE_7 c hypo c hypo, possible glutathione disulfide isomeraseLeptoII_scaffold_287_GENE_8 41-37=tRNA Leu=47-38 chloride channel protein [Inorganic ion transport and metabolism]LeptoII_scaffold_41_GENE_37287-8+=tRNA Arg, 41-37/38=tRNA Leu hypo unique hypo uniqueLeptoII_scaffold_41_GENE_36 NADH dehydrogenase [Energy production and conversion]LeptoII_scaffold_41_GENE_35 cysteine desulfhydrase [Amino acid transport and metabolism]LeptoII_scaffold_41_GENE_34 c hypo c hypoLeptoII_scaffold_41_GENE_33 glycerol-3-phosphate dehydrogenase [Energy production and conversion]LeptoII_scaffold_41_GENE_32 hypo unique hypo uniqueLeptoII_scaffold_41_GENE_31 succinyl-CoA synthetase/acyl-CoA synthetase [Energy production and conversion]LeptoII_scaffold_41_GENE_30 iron-dependent peroxidase, tyrA protein [Defense mechanisms]LeptoII_scaffold_41_GENE_29 bacterioferritin comigratory protein/peroxiredoxin [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_41_GENE_28 beta-hydroxyacid dehydrogenase [Lipid metabolism]LeptoII_scaffold_41_GENE_27 hypo unique hypo uniqueLeptoII_scaffold_41_GENE_26 hypo unique hypo uniqueLeptoII_scaffold_41_GENE_25 K+-transporting ATPase D chain/sensor histidine kinase [Signal transduction mechanisms]LeptoII_scaffold_41_GENE_24 hypo unique hypo uniqueLeptoII_scaffold_41_GENE_23 hypo unique hypo uniqueLeptoII_scaffold_41_GENE_22 hypo unique hypo uniqueLeptoII_scaffold_41_GENE_21 hypo unique hypo uniqueLeptoII_scaffold_41_GENE_20 hypo unique hypo uniqueLeptoII_scaffold_41_GENE_19 K+-transporting ATPase B chain [Inorganic ion transport and metabolism]LeptoII_scaffold_41_GENE_18 K+-transporting ATPase A chain [Inorganic ion transport and metabolism]LeptoII_scaffold_41_GENE_17 K+-transporting ATPase C chain [Inorganic ion transport and metabolism]LeptoII_scaffold_41_GENE_16 hypo unique hypo uniqueLeptoII_scaffold_41_GENE_15 cationic amino acid transporter (cat-1) [Amino acid transport and metabolism]LeptoII_scaffold_41_GENE_14 sensor histidine kinase [Signal transduction mechanisms]LeptoII_scaffold_41_GENE_13 two-component response regulator [Signal transduction mechanisms ]LeptoII_scaffold_41_GENE_12 ADP-heptose-LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_41_GENE_11 multidrug efflux permease [Defense mechanisms]LeptoII_scaffold_41_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_41_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_41_GENE_8 transporter/DNA photolyase [DNA replication, recombination, and repair]LeptoII_scaffold_41_GENE_7 sulfide:quinone reductase [Energy production and conversion]LeptoII_scaffold_41_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_41_GENE_5 cytochrome bd quinol oxidase, subunit II [Energy production and conversion]LeptoII_scaffold_41_GENE_4 cytochrome bd quinol oxidase, subunit I [Energy production and conversion]LeptoII_scaffold_41_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_41_GENE_2 chemotaxis protein CheY [Transcription]LeptoII_scaffold_41_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_443_GENE_1 T11 transposase transposaseLeptoII_scaffold_443_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_443_GENE_9 T (single) transposase transposaseLeptoII_scaffold_443_GENE_8 T (single) transposase transposase

LeptoII_scaffold_443_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_443_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_443_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_443_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_443_GENE_3 integrase Rci fragment integrase Rci fragment (partial domain) [Transcription]LeptoII_scaffold_443_GENE_2 plasmid transposition helper IstB transposition helper protein, IstB [DNA replication, recombination, and repair]LeptoII_scaffold_443_GENE_1 T 443-1/0=tRNA Met transposase transposaseLeptoII_scaffold_303_GENE_9 303-9=tRNA Met =303-10 hypo unique hypo uniqueLeptoII_scaffold_303_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_303_GENE_7 drug resistance transporter [Defense mechanisms]LeptoII_scaffold_303_GENE_6 Fe-S oxidoreductase/methyltransferase [Energy production and conversion]LeptoII_scaffold_303_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_303_GENE_4 hypo unique hypo unique (like transcriptional regulators)LeptoII_scaffold_303_GENE_3 sulfate adenylyl transferase (sulfate to APS) [Energy production and conversion]LeptoII_scaffold_303_GENE_2 adenylylsulfate reductase, subunit B [Energy production and conversion]LeptoII_scaffold_303_GENE_1 adenylylsulfate reductase, subunit A (APS to sulfite) [Energy production and conversion]

LeptoII-2: LeptoII_scaffold_374_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_374_GENE_2 transposase-likeLeptoII_scaffold_374_GENE_3 T12 transposase transposaseLeptoII_scaffold_374_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_374_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_374_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_374_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_374_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_374_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_374_GENE_10 conserved hypothetical, like cellulose synthase operon proteinLeptoII_scaffold_4_GENE_100 c hypo c hypoLeptoII_scaffold_4_GENE_99 carbon-nitrogen hydrolase domain protein [General function prediction only]LeptoII_scaffold_4_GENE_98 pantoate-beta-alanine ligase [Coenzyme metabolism]LeptoII_scaffold_4_GENE_97 corrin/porphyrin methyltransferase [Coenzyme metabolism]LeptoII_scaffold_4_GENE_96 deoxyuridinetriphosphatase [Nucleotide transport and metabolism]LeptoII_scaffold_4_GENE_95 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_94 acetyl glutamate kinase [Amino acid transport and metabolism]LeptoII_scaffold_4_GENE_93 ATP-dependent HslU protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_4_GENE_92 heat shock protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_4_GENE_91 integrase XerDC phage/plasmid/ICE integrase (domain complete) [DNA replication, recombination, and repair]LeptoII_scaffold_4_GENE_90 glucose-inhibited division protein A [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_4_GENE_89 DNA topoisomerase I [DNA replication, recombination, and repair]LeptoII_scaffold_4_GENE_88 DNA processing protein DprA [DNA replication, recombination, and repair]LeptoII_scaffold_4_GENE_87 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_86 ABC transporter, ATP-binding protein involved in anion transp. [Inorganic ion transport and metabolism]LeptoII_scaffold_4_GENE_85 ABC transporter, ATP-binding protein involved in anion transport [Inorganic ion transport and metabolism]LeptoII_scaffold_4_GENE_84 ABC transporter, permease protein involved in anion transport [Inorganic ion transport and metabolism]LeptoII_scaffold_4_GENE_83 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_82 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_81 c hypo c hypoLeptoII_scaffold_4_GENE_80 c hypo c hypoLeptoII_scaffold_4_GENE_79 adenine glycosylase [DNA replication, recombination, and repair]LeptoII_scaffold_4_GENE_78 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_77 7,8-dihydro-6-hydroxymethylpterin-pyrophosphokinase FolK [Coenzyme metabolism]LeptoII_scaffold_4_GENE_76 aminotransferase [Amino acid transport and metabolism]LeptoII_scaffold_4_GENE_75 hypo unique hypo unique found in alternative reading frameLeptoII_scaffold_4_GENE_74 hypo unique hypo unique found in alternative reading frameLeptoII_scaffold_4_GENE_73 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_72 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_71 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_70 dehydrogenase [General function prediction only]LeptoII_scaffold_4_GENE_69 flagellar biosynthetic protein, FlhB [Cell motility and secretion]LeptoII_scaffold_4_GENE_68 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_67 hypo unique hypo unique - probably chemotaxis/flagella-relatedLeptoII_scaffold_4_GENE_66 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_65 flagellar motor protein, MotB [Cell motility and secretion]LeptoII_scaffold_4_GENE_64 flagellar motor protein, MotA [Cell motility and secretion]LeptoII_scaffold_4_GENE_63 purine-binding chemotaxis protein, CheW [Cell motility and secretion]LeptoII_scaffold_4_GENE_62 methyl-accepting chemotaxis protein [Cell motility and secretion]LeptoII_scaffold_4_GENE_61 protein-glutamate methylesterase [Cell motility and secretion]LeptoII_scaffold_4_GENE_60 chemotaxis histidine kinase [Cell motility and secretion]LeptoII_scaffold_4_GENE_59 chemotaxis protein CheY [Cell motility and secretion]LeptoII_scaffold_4_GENE_58 chemotaxis protein methyltransferase CheR [Cell motility and secretion]

LeptoII_scaffold_4_GENE_57 Rna polymerase sigma factor for flagellar operon [Cell motility and secretion]LeptoII_scaffold_4_GENE_56 chromosome partitioning ATPase [Cell divison and chromosome partitioning]LeptoII_scaffold_4_GENE_55 flagellar biosynthesis protein FlhF [Cell motility and secretion]LeptoII_scaffold_4_GENE_54 flagellar biosynthetic protein FlhA [Cell motility and secretion]LeptoII_scaffold_4_GENE_53 flagellar biosynthesis protein, FlhB [Cell motility and secretion]LeptoII_scaffold_4_GENE_52 flagellar biosynthesis protein, FliR [Cell motility and secretion]LeptoII_scaffold_4_GENE_51 Chemotaxis/flagella (novel lepto genera) [Cell motility and secretion]LeptoII_scaffold_4_GENE_50 flagellar biosynthetic protein, FliP [Cell motility and secretion]LeptoII_scaffold_4_GENE_49 hypo unique hypo unique, possible flagellar assembly protein FliOLeptoII_scaffold_4_GENE_48 flagellar motor switch [Cell motility and secretion]LeptoII_scaffold_4_GENE_47 flagellar protein FliL [Cell motility and secretion]LeptoII_scaffold_4_GENE_46 flagellar hook protein [Cell motility and secretion]LeptoII_scaffold_4_GENE_45 flagellar hook protein [Cell motility and secretion]LeptoII_scaffold_4_GENE_44 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_43 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_42 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_41 flagellar-type ATPase, FliI [Cell motility and secretion]LeptoII_scaffold_4_GENE_40 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_39 flagellar motor switch protein, FliG [Cell motility and secretion]LeptoII_scaffold_4_GENE_38 flagellar M-ring protein, FliF [Cell motility and secretion]LeptoII_scaffold_4_GENE_37 flagellar basal body protein, FliE [Cell motility and secretion]LeptoII_scaffold_4_GENE_36 flagellar basal body protein, FlgC [Cell motility and secretion]LeptoII_scaffold_4_GENE_35 flagellar basal body protein, FlgB [Cell motility and secretion]LeptoII_scaffold_4_GENE_34 sigma54-dependant response regulator, FleR [Signal transduction mechanisms]LeptoII_scaffold_4_GENE_33 sensory box histidine kinase [Signal transduction mechanisms]LeptoII_scaffold_4_GENE_32 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_31 flagellar protein FleQ, transcriptional regulator [Cell motility and secretion]LeptoII_scaffold_4_GENE_30 Fe-S cluster binding protein [Energy production and conversion]LeptoII_scaffold_4_GENE_29 c hypo c hypo (contains HD domain)LeptoII_scaffold_4_GENE_28 c hypo c hypo (contains HD domain)LeptoII_scaffold_4_GENE_27 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_26 lipoate protein ligase [Coenzyme metabolism]LeptoII_scaffold_4_GENE_25 glycine dehydrogenase [Amino acid transport and metabolism]LeptoII_scaffold_4_GENE_24 glycine cleavage system P protein, subunit 1 [Amino acid transport and metabolism]LeptoII_scaffold_4_GENE_23 glycine cleavage system protein [Amino acid transport and metabolism]LeptoII_scaffold_4_GENE_22 glycine cleavage system T protein [Amino acid transport and metabolism]LeptoII_scaffold_4_GENE_21 hypo unique hypo unique, possible peptidyl-prolyl cis-trans isomeraseLeptoII_scaffold_4_GENE_20 methyl-accepting chemotaxis protein [Cell motility and secretion / Signal transduction mechanisms]LeptoII_scaffold_4_GENE_19 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_18 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_17 c hypo c hypo, possible ABC transporter, periplasmic componentLeptoII_scaffold_4_GENE_16 hypo unique hypo unique - abundantLeptoII_scaffold_4_GENE_15 sulfurylase/sulfur transferase [Inorganic ion transport and metabolism]LeptoII_scaffold_4_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_13 SAM-dependent methyltransferase [Amino acid transport and metabolism]LeptoII_scaffold_4_GENE_12 methyl transferase [General function prediction only]LeptoII_scaffold_4_GENE_11 c hypo c hypo, possible cytochrome c biogenesis thioredoxinLeptoII_scaffold_4_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_8 diaminopimelate epimerase [Amino acid transport and metabolism]LeptoII_scaffold_4_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_4_GENE_6 short chain dehydrogenase [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_4_GENE_5 DnaK suppressor protein [Signal transduction mechanisms]LeptoII_scaffold_4_GENE_4 oxidoreductase [General function prediction only]LeptoII_scaffold_4_GENE_3 metal efflux system protein [Defense]LeptoII_scaffold_4_GENE_2 cation efflux protein [Defense]LeptoII_scaffold_4_GENE_1 outer membrane efflux protein [Defense]LeptoII_scaffold_59_GENE_28 hypo unique hypo uniqueLeptoII_scaffold_59_GENE_27 lipoprotein [General function prediction only]LeptoII_scaffold_59_GENE_26 hypo unique hypo uniqueLeptoII_scaffold_59_GENE_25 hypo unique hypo uniqueLeptoII_scaffold_59_GENE_24 hypo unique hypo uniqueLeptoII_scaffold_59_GENE_23 hypo unique hypo uniqueLeptoII_scaffold_59_GENE_22 hypo unique hypo uniqueLeptoII_scaffold_59_GENE_21 DNA polymerase III, gamma and tau subunits [DNA replication, recombination, and repair]LeptoII_scaffold_59_GENE_20 59-21=tRNA Ser=59-22 c hypo c hypo LeptoII_scaffold_59_GENE_19 recombination protein, RecR [DNA replication, recombination, and repair]LeptoII_scaffold_59_GENE_18 peptide chain release factor 3 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_59_GENE_17 59-16=tRNA Ser=59-17 potassium efflux system KefA [Inorganic ion transport and metabolism]

LeptoII_scaffold_59_GENE_16 59-16=tRNA Ser=59-17 c hypo c hypoLeptoII_scaffold_59_GENE_15 cytidine/deoxycytidylate deaminase [Nucleotide transport and metabolism]LeptoII_scaffold_59_GENE_14 59-14=tRNA Ser=59-15 sigma 54 dependant DNA-binding response regulator [Transcription]LeptoII_scaffold_59_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_59_GENE_12 tetrapyrrole methylase family [Coenzyme metabolism]LeptoII_scaffold_59_GENE_11 anthranilate synthase component II [Amino acid transport and metabolism]LeptoII_scaffold_59_GENE_10 c hypo c hypo (HD hydrolase domain protein)LeptoII_scaffold_59_GENE_9 c hypo c hypoLeptoII_scaffold_59_GENE_8 c hypo c hypoLeptoII_scaffold_59_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_59_GENE_6 acid phosphatase [General function prediction only]LeptoII_scaffold_59_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_59_GENE_4 DAHP synthase in aromatic amino acid biosynthesis… [Energy production and conversion]LeptoII_scaffold_59_GENE_3 59-3=tRNA Met=59-4 c hypo c hypo LeptoII_scaffold_59_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_59_GENE_1 two component response regulatorLeptoII_scaffold_333_GENE_1 T4 transposase transposaseLeptoII_scaffold_333_GENE_5 two component response regulator [Signal transduction mechanisms]LeptoII_scaffold_333_GENE_6 uracil-DNA glycosylase [DNA replication, recombination, and repair]LeptoII_scaffold_333_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_333_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_333_GENE_9 hypo unique hypo unique; Abundant Mem (integral memb)LeptoII_scaffold_333_GENE_10 exoribonuclease R [Transcription]LeptoII_scaffold_3_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_3 T6 transposase transposaseLeptoII_scaffold_3_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_5 peptidoglycan-associated lipoprotein [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_3_GENE_6 c hypo c hypo, possible peptidoglycan-associated lipoproteinLeptoII_scaffold_3_GENE_7 c hypo c hypoLeptoII_scaffold_3_GENE_8 thiamine monophosphate kinase ThiL [Coenzyme metabolism]LeptoII_scaffold_3_GENE_9 ATP-dependant Lon protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_3_GENE_10 UDP-glucose pyrophosphorylase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_3_GENE_11 dephospho-coA kinase [Coenzyme metabolism]LeptoII_scaffold_3_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_13 hypo unique hypo unique, possible O-linked glycosyltransferaseLeptoII_scaffold_3_GENE_14 DNA polymerase I [DNA replication, recombination, and repair]LeptoII_scaffold_3_GENE_15 branched-chain amino acid transferase [Amino acid transport and metabolism]LeptoII_scaffold_3_GENE_16 transport permease [General function prediction only]LeptoII_scaffold_3_GENE_17 c hypo c hypoLeptoII_scaffold_3_GENE_18 c hypo c hypoLeptoII_scaffold_3_GENE_19 transcriptional regulator [Transcription]LeptoII_scaffold_3_GENE_20 ATP-dependant helicase [Transcription]LeptoII_scaffold_3_GENE_21 competence protein F competence protein F [General function prediction only]LeptoII_scaffold_3_GENE_22 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_23 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_24 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_25 nicotinate-nucleotide adenylyltransferase [Coenzyme metabolism]LeptoII_scaffold_3_GENE_26 gamma glutamyl phosphate reductase [Amino acid transport and metabolism]LeptoII_scaffold_3_GENE_27 gamma glutamyl kinase [Amino acid transport and metabolism]LeptoII_scaffold_3_GENE_28 SpoOB-associated GTP-binding protein [General function prediction only]LeptoII_scaffold_3_GENE_29 ribosomal protein L27 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_3_GENE_30 ribosomal protein L21 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_3_GENE_31 ferric uptake regulator [Inorganic ion transport and metabolism]LeptoII_scaffold_3_GENE_32 BNR domain protein [General function prediction only]LeptoII_scaffold_3_GENE_33 T5, T6 transposase transposaseLeptoII_scaffold_3_GENE_34 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_35 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_36 6-pyruvoly tetrahydrobiopterin synthase [Coenzyme metabolism]LeptoII_scaffold_3_GENE_37 ABC transporter ATP-binding protein [Amino acid transport and metabolism]LeptoII_scaffold_3_GENE_38 oligopeptide ABC transporter [Amino acid transport and metabolism]LeptoII_scaffold_3_GENE_39 phenylalanyl tRNa synthetase, alpha subunit [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_3_GENE_40 phenylalanyl tRNa synthetase, beta subunit [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_3_GENE_41 ribosomal protein L20 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_3_GENE_42 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_43 translation initiation factor IF3 N-terminal domain [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_3_GENE_44 hypo unique hypo unique, possible translation initiation factorLeptoII_scaffold_3_GENE_45 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_3_GENE_46 hydroxymethylpyrimidine kinase ThiD [Nucleotide transport and metabolism]LeptoII_scaffold_3_GENE_47 peptidase, M23/M37 family [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_3_GENE_48 thiamine phosphate pyrophosphorylase ThiE [Coenzyme metabolism]

LeptoII_scaffold_3_GENE_49 thiamine biosynthesis protein ThiG [Nucleotide transport and metabolism]LeptoII_scaffold_3_GENE_50 acyl-coenzyme A synthetase [Lipid metabolism]LeptoII_scaffold_3_GENE_51 lactoylglutathione lyase [Amino acid transport and metabolism]LeptoII_scaffold_3_GENE_52 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_53 1,2-diacylglycerol 3-glucosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_3_GENE_54 c hypo c hypoLeptoII_scaffold_3_GENE_55 multidrug efflux transporter [Defense]LeptoII_scaffold_3_GENE_56 dienelactone hydrolase [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_3_GENE_57 quinoprotein dehydrogenase/outer membrane protein [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_3_GENE_58 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_59 two component sensor histidine kinase [Signal transduction mechanisms]LeptoII_scaffold_3_GENE_60 two component response regulator [Signal transduction mechanisms]LeptoII_scaffold_3_GENE_61 3-61=tRNA Pro=3-62 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_62 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_63 zinc-dependant hydrolase [General function prediction only]LeptoII_scaffold_3_GENE_64 ATP synthase, epsilon subunit [Energy production and conversion]LeptoII_scaffold_3_GENE_65 ATPsynth.membrane, abundant [Energy production and conversion]LeptoII_scaffold_3_GENE_66 ATP synthase, gamma subunit [Energy production and conversion]LeptoII_scaffold_3_GENE_67 ATP synthase, alpha subunit [Energy production and conversion]LeptoII_scaffold_3_GENE_68 hypo unique hypo unique (sim. to ATP synthase, delta subunit) LeptoII_scaffold_3_GENE_69 ATP synthase, beta subunit [Energy production and conversion]LeptoII_scaffold_3_GENE_70 ATP synthase, subunit c [Energy production and conversion]LeptoII_scaffold_3_GENE_71 ATP synthase, subunit a [Energy production and conversion]LeptoII_scaffold_3_GENE_72 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_73 c hypo c hypoLeptoII_scaffold_3_GENE_74 phosphoglycolate phosphatase [Carbohyhrate transport and metabolism]LeptoII_scaffold_3_GENE_75 peptide ABC transporter [Amino acid transport and metabolism]LeptoII_scaffold_3_GENE_76 peptide ABC transporter [Amino acid transport and metabolism]LeptoII_scaffold_3_GENE_77 periplasmic oligopeptide-binding protein of oligopeptide A [Amino acid transport and metabolism]LeptoII_scaffold_3_GENE_78 preprotein translocase SecG [Intracellular trafficking and secretion]LeptoII_scaffold_3_GENE_79 triosephosphate isomerase [Carbohyhrate transport and metabolism]LeptoII_scaffold_3_GENE_80 phosphoglycerate kinase [Carbohyhrate transport and metabolism]LeptoII_scaffold_3_GENE_81 glyceraldehyde-3-phosphate dehydrogenase [Carbohyhrate transport and metabolism]LeptoII_scaffold_3_GENE_82 penicillin-binding protein [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_3_GENE_83 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_84 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_85 uridine 5-monophosphate synthase [Nucleotide transport and metabolism]LeptoII_scaffold_3_GENE_86 methyl-accepting chemotaxis protein [Cell motility and secretion]LeptoII_scaffold_3_GENE_87 3-87=tRNA Leu=3-88 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_88 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_89 siroheme synthase [Coenzyme metabolism]LeptoII_scaffold_3_GENE_90 competence ComL competence protein ComL [General function prediction only]LeptoII_scaffold_3_GENE_91 3-oxoacyl-(acyl-carrier-protein)synthase II [Lipid metabolism]LeptoII_scaffold_3_GENE_92 nitrogen regulation protein NtrX [Signal transduction mechanisms]LeptoII_scaffold_3_GENE_93 nitrogen regulation protein NtrY/signal transd. histidine kinase [Signal transduction mechanisms]LeptoII_scaffold_3_GENE_94 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_95 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_96 antibiotic resistance MarC-like multiple antibiotic resistance protein MarC [Defense]LeptoII_scaffold_3_GENE_97 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_98 hypo unique hypo uniqueLeptoII_scaffold_3_GENE_99 S-adenosylmethionine tRNA ribosyl transferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_3_GENE_100 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_3_GENE_101 c hypo c hypoLeptoII_scaffold_3_GENE_102 c hypo c hypoLeptoII_scaffold_3_GENE_103 sulfide-quinone reductase (147-16) [Energy production and conversion]LeptoII_scaffold_3_GENE_104 carbonic anhydrase [Inorganic ion transport and metabolism]LeptoII_scaffold_147_GENE_14 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_147_GENE_13 hypo unique hypo unique LeptoII_scaffold_147_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_147_GENE_11 helicase [DNA replication, recombination, and repair]LeptoII_scaffold_147_GENE_10 NTP pyrophosphohydrolase [Nucleotide transport and metabolism]LeptoII_scaffold_147_GENE_9 two component response regulator [Signal transduction mechanisms]LeptoII_scaffold_147_GENE_8 serine protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_147_GENE_7 alcohol dehydrogenase [Energy production and conversion]LeptoII_scaffold_147_GENE_6 allophanate hydrolase [General function prediction only]LeptoII_scaffold_147_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_147_GENE_4 transporter [General function prediction only]LeptoII_scaffold_147_GENE_3 c hypo c hypoLeptoII_scaffold_147_GENE_2 c hypo c hypo (predicted transcriptional regulator)LeptoII_scaffold_147_GENE_1 c hypo c hypo - conserved repetitive aa motifs

LeptoII-3: LeptoIII_scaffold_449_GENE_2 Type II restriction enzyme, methylase subunit [Defense mechanisms]LeptoII_scaffold_69_GENE_1 Superfamily II DNA/RNA helicases [Transcription]LeptoII_scaffold_69_GENE_2 c hypo c hypoLeptoII_scaffold_69_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_69_GENE_4 T (single) transposase transposaseLeptoII_scaffold_69_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_69_GENE_6 DeaD/DeaH box helicase [DNA replication, recombination, and repair]LeptoII_scaffold_69_GENE_7 RNA helicase [DNA replication, recombination, and repair]LeptoII_scaffold_69_GENE_8 restriction endonuclease [Defense mechanisms]LeptoII_scaffold_69_GENE_9 T (single) transposase transposaseLeptoII_scaffold_69_GENE_10 c hypo c hypoLeptoII_scaffold_69_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_69_GENE_12 sulfate permease [Inorganic ion transport and metabolism]LeptoII_scaffold_69_GENE_13 universal stress protein [General function prediction only]LeptoII_scaffold_69_GENE_14 c hypo c hypoLeptoII_scaffold_69_GENE_15 c hypo c hypoLeptoII_scaffold_69_GENE_16 hypo unique hypo uniqueLeptoII_scaffold_69_GENE_17 hypo unique hypo uniqueLeptoII_scaffold_69_GENE_18 c hypo c hypoLeptoII_scaffold_69_GENE_19 T (single) transposase transposaseLeptoII_scaffold_69_GENE_20 T (single) transposase transposaseLeptoII_scaffold_69_GENE_21 c hypo c hypoLeptoII_scaffold_69_GENE_22 c hypo c hypoLeptoII_scaffold_69_GENE_23 hypo unique hypo uniqueLeptoII_scaffold_69_GENE_24 c hypo c hypoLeptoII_scaffold_69_GENE_25 hypo unique hypo unique found in alternative reading frameLeptoII_scaffold_69_GENE_26 hypo unique hypo uniqueLeptoII_scaffold_69_GENE_27 T11 transposase transposaseLeptoII_scaffold_69_GENE_28 hypo unique hypo uniqueLeptoII_scaffold_69_GENE_29 hypo unique hypo uniqueLeptoII_scaffold_141_GENE_1 T6 hypo unique hypo uniqueLeptoII_scaffold_141_GENE_14 serine protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_141_GENE_13 c hypo c hypoLeptoII_scaffold_141_GENE_12 c hypo c hypoLeptoII_scaffold_141_GENE_11 c hypo c hypoLeptoII_scaffold_141_GENE_10 c hypo c hypoLeptoII_scaffold_141_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_141_GENE_8 DNA repair exonuclease [DNA replication, recombination, and repair]LeptoII_scaffold_141_GENE_7 c hypo c hypoLeptoII_scaffold_141_GENE_6 c hypo c hypoLeptoII_scaffold_141_GENE_5 c hypo c hypoLeptoII_scaffold_141_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_141_GENE_3 outer membrane protein OmpA [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_141_GENE_2 unique hypo hypo uniqueLeptoII_scaffold_8_GENE_70 unique hypo hypo uniqueLeptoII_scaffold_8_GENE_69 multidrug ABC transporter, ATP binding subunit [Defense mechanisms]LeptoII_scaffold_8_GENE_68 hypo unique hypo uniqueLeptoII_scaffold_8_GENE_67 drug resistance transporter drug resistance transporter [Defense mechanisms]LeptoII_scaffold_8_GENE_66 cbb3-type cytochrome oxidase, subunit I/CcoN [Energy production and conversion]LeptoII_scaffold_8_GENE_65 T (single) transposase transposaseLeptoII_scaffold_8_GENE_64 phosphoglucomutase [Carbohyhrate transport and metabolism]LeptoII_scaffold_8_GENE_63 maltodextrin phosphorylase [Carbohyhrate transport and metabolism]LeptoII_scaffold_8_GENE_62 cell division inhibitor (nucleoside diphosphate sugar epimerase) [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_8_GENE_61 dihydrolipoamide dehydrogenase [Energy production and conversion]LeptoII_scaffold_8_GENE_60 fructose bisphophate aldolase [Carbohyhrate transport and metabolism]LeptoII_scaffold_8_GENE_59 phosphoketolase [Carbohyhrate transport and metabolism]LeptoII_scaffold_8_GENE_58 cytochrome c-551 (58% to 689-3) [Energy production and conversion]LeptoII_scaffold_8_GENE_57 outer membrane efflux protein [General function prediction only]LeptoII_scaffold_8_GENE_56 HlyD family secretion protein [Defense mechanisms]LeptoII_scaffold_8_GENE_55 ABC transporter, ATP binding protein, YbhF [General function prediction only]LeptoII_scaffold_8_GENE_54 ABC transporter, ATP binding protein [General function prediction only]LeptoII_scaffold_8_GENE_53 ABC transporter, permease protein [General function prediction only]LeptoII_scaffold_8_GENE_52 biopolymer transport protein, ExbB [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_8_GENE_51 TonB system transport protein, ExbD [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_8_GENE_50 TonB protein [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_8_GENE_49 ferrichrome-iron receptor [Inorganic ion transport and metabolism]LeptoII_scaffold_8_GENE_48 ubiquinone/menaquinone biosynthesis methyltransferase [Coenzyme metabolism]LeptoII_scaffold_8_GENE_47 acetate kinase [Energy production and conversion]LeptoII_scaffold_8_GENE_46 L-aspariginase [Amino acid transport and metabolism]

LeptoII_scaffold_8_GENE_45 hypo unique hypo uniqueLeptoII_scaffold_8_GENE_44 phosphoribosylformylglycinamidine synthase, PurS [Nucleotide transport and metabolism]LeptoII_scaffold_8_GENE_43 phosphoribosyl aminoimidazole succinocarboxamide synthase [Nucleotide transport and metabolism]LeptoII_scaffold_8_GENE_42 adenylosuccinate lyase [Nucleotide transport and metabolism]LeptoII_scaffold_8_GENE_41 hypo unique hypo uniqueLeptoII_scaffold_8_GENE_40 N utilization substance protein B [Transcription]LeptoII_scaffold_8_GENE_39 riboflavin synthase [Coenzyme metabolism]LeptoII_scaffold_8_GENE_38 GTP cyclohydrolase II [Coenzyme metabolism]LeptoII_scaffold_8_GENE_37 NH(3)-dependent NAD+ synthetase [Coenzyme metabolism]LeptoII_scaffold_8_GENE_36 thiol disulfide isomerae [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_8_GENE_35 tRNA/rRNA methyltransferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_8_GENE_34 cytsteinyl tRNA synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_8_GENE_33 hypo unique hypo uniqueLeptoII_scaffold_8_GENE_32 acid phosphatase [General function prediction only]LeptoII_scaffold_8_GENE_31 8-31=tRNA Pro=8-32 hypo unique hypo uniqueLeptoII_scaffold_8_GENE_30 integration host factor HimA/histone-like [Transcription]LeptoII_scaffold_8_GENE_29 UDP-N-acetylglucosamine acyltransferase [Lipid metabolism]LeptoII_scaffold_8_GENE_28 2-isopropylmalate synthase [Amino acid transport and metabolism]LeptoII_scaffold_8_GENE_27 aspartate kinase [Amino acid transport and metabolism]LeptoII_scaffold_8_GENE_26 phosphonopyruvate decarboxylase [Carbohyhrate transport and metabolism]LeptoII_scaffold_8_GENE_25 threonine synthase [Amino acid transport and metabolism]LeptoII_scaffold_8_GENE_24 homoserine dehydrogenase [Amino acid transport and metabolism]LeptoII_scaffold_8_GENE_23 hypo unique hypo uniqueLeptoII_scaffold_8_GENE_22 aminotransferase [Amino acid transport and metabolism]LeptoII_scaffold_8_GENE_21 T6 transposase transposaseLeptoII_scaffold_8_GENE_20 hypo unique hypo unique - abundant in extracellular fractionLeptoII_scaffold_8_GENE_19 hypo unique hypo uniqueLeptoII_scaffold_8_GENE_18 hypo unique hypo uniqueLeptoII_scaffold_8_GENE_17 SAM-dependant methyl transferase [Amino acid transport and metabolism]LeptoII_scaffold_8_GENE_16 hypo unique hypo uniqueLeptoII_scaffold_8_GENE_15 2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_8_GENE_14 c hypo permease-likeLeptoII_scaffold_8_GENE_13 c hypo permease-likeLeptoII_scaffold_8_GENE_12 ferrochelatase [Coenzyme metabolism]LeptoII_scaffold_8_GENE_11 glycogen debranching enzyme [Carbohyhrate transport and metabolism]LeptoII_scaffold_8_GENE_10 translation initiation factor [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_8_GENE_9 lysyl tRNA synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_8_GENE_8 ABC transporter, permease protein [Defense mechanisms]LeptoII_scaffold_8_GENE_7 ABC transporter, ATP-binding prot. Inv. in antimicrob. transport [Defense mechanisms]LeptoII_scaffold_8_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_8_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_8_GENE_4 aspartate aminotransferase [Amino acid transport and metabolism]LeptoII_scaffold_8_GENE_3 pantetheine-phosphate adenylyltransferase [Coenzyme metabolism]LeptoII_scaffold_8_GENE_2 methyltransferase [General function prediction only]LeptoII_scaffold_8_GENE_1 hypo unique hypo unique - similar to lytic enzyme/peptidoglycan binding proteinLeptoII_scaffold_68_GENE_1 translation factor sua5-like [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_68_GENE_2 phosphoribosylamine-glycine ligase [Nucleotide transport and metabolism]LeptoII_scaffold_68_GENE_3 phosphoribosylaminoimidazolecarboxamide formyltransferase [Nucleotide transport and metabolism]LeptoII_scaffold_68_GENE_4 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_68_GENE_5 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_68_GENE_6 ADP-heptose-LPS heptosyltransferase II [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_68_GENE_7 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_68_GENE_8 Pap2 superfamily protein/permease [Lipid metabolism]LeptoII_scaffold_68_GENE_9 serine acetyltransferase [Amino acid transport and metabolism]LeptoII_scaffold_68_GENE_10 IspD/IspF bifunctional enzyme [Lipid metabolism]LeptoII_scaffold_68_GENE_11 pili retraction protein PilT [Cell motility and secretion]LeptoII_scaffold_68_GENE_12 c hypo c hypoLeptoII_scaffold_68_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_68_GENE_14 serine protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_68_GENE_15 adenosylmethionine-8-amino-7-oxononanoate aminotransferase [Coenzyme metabolism]LeptoII_scaffold_68_GENE_16 hypo unique hypo uniqueLeptoII_scaffold_68_GENE_17 diacylglycerol kinase [Lipid metabolism]LeptoII_scaffold_68_GENE_18 hypo unique hypo uniqueLeptoII_scaffold_68_GENE_19 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_68_GENE_20 polysaccharide deacetylase [Carbohyhrate transport and metabolism]LeptoII_scaffold_68_GENE_21 ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_68_GENE_22 ADP-heptose:LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_68_GENE_23 tetraacyldisaccharide-1-P 4'-kinase [Lipid metabolism]LeptoII_scaffold_68_GENE_24 histidinol phosphatase [Amino acid transport and metabolism]LeptoII_scaffold_68_GENE_25 heptosyltransferase [Cell envelope biogenesis, outer membrane]

LeptoII_scaffold_68_GENE_26 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_68_GENE_27 c hypo c hypoLeptoII_scaffold_68_GENE_28 T9 transposase transposaseLeptoII_scaffold_6_GENE_1 T13 transposase transposaseLeptoII_scaffold_6_GENE_2 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_6_GENE_3 c hypo c hypoLeptoII_scaffold_6_GENE_4 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_6_GENE_5 lipopolysaccharide heptosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_6_GENE_6 lipopolysaccharide heptosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_6_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_8 lipid A biosynthesis lauroyl acyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_6_GENE_9 tetraacyldisaccharide 4'-kinase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_6_GENE_10 3-deoxy-manno-octulosonic acid transferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_6_GENE_11 ABC transporter, ATP-binding protein, MsbA family [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_6_GENE_12 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_6_GENE_13 lipid A disaccharide synthase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_6_GENE_14 oxidoreductase [General function prediction only]LeptoII_scaffold_6_GENE_15 phosphatide cytidyltransferase [Lipid metabolism]LeptoII_scaffold_6_GENE_16 acetyl transferase [Lipid metabolism]LeptoII_scaffold_6_GENE_17 UDP-3-O-3-hydroxymyristoyl N-acetylglucosamine deac… [Lipid metabolism]LeptoII_scaffold_6_GENE_18 N-acetyltransferase [Lipid metabolism]LeptoII_scaffold_6_GENE_19 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_20 6-20=tRNA Phe=6-21 outer membrane protein [General function prediction only]LeptoII_scaffold_6_GENE_21 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_22 hypo unique hypo unique, poss. isocitrate dehydrog., abund. Ext., mem. fractionsLeptoII_scaffold_6_GENE_23 isocitrate dehydrogenase (reductive TCA), abundant memb. [Amino acid transport and metabolism]LeptoII_scaffold_6_GENE_24 precorrin isomerase [Coenzyme metabolism]LeptoII_scaffold_6_GENE_25 cobyrinic acid [Coenzyme metabolism]LeptoII_scaffold_6_GENE_26 phosphoglycerate mutase [Carbohyhrate transport and metabolism]LeptoII_scaffold_6_GENE_27 aldo/keto reductase [Energy production and conversion]LeptoII_scaffold_6_GENE_28 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_29 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_30 cobalamin synthase/intracellular sulfur reduction protein [Inorganic ion transport and metabolism]LeptoII_scaffold_6_GENE_31 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_32 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_33 hypo unique hypo unique found in alternative reading frameLeptoII_scaffold_6_GENE_34 cobalamin synthase [Coenzyme metabolism]LeptoII_scaffold_6_GENE_35 nicotinate-nucleotide dimethybenzimidazole phosphoribosyltransf[Coenzyme metabolism]LeptoII_scaffold_6_GENE_36 cobinamide kinase [Coenzyme metabolism]LeptoII_scaffold_6_GENE_37 methyl chloride transferase [General function prediction only]LeptoII_scaffold_6_GENE_38 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_39 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_40 heat shock protein dnaJ [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_6_GENE_41 chaperone dnaK, AbMem protein [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_6_GENE_42 chaperone grpE [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_6_GENE_43 heat inducible transcription repressor, HrcA [Transcription]LeptoII_scaffold_6_GENE_44 drug resistance transporter drug resistance transporter [Defense mechanisms]LeptoII_scaffold_6_GENE_45 efflux transporter for multidrug resistance [Defense mechanisms]LeptoII_scaffold_6_GENE_46 efflux protein involved in multidrug resistance [Defense mechanisms]LeptoII_scaffold_6_GENE_47 drug resistance transporter drug resistance transporter [Defense mechanisms]LeptoII_scaffold_6_GENE_48 multi-drug resistance efflux pump [Defense mechanisms]LeptoII_scaffold_6_GENE_49 c hypo c hypo, possible cytochrome c-554 precursor (unique in community)LeptoII_scaffold_6_GENE_50 transcriptional regulator [Transcription]LeptoII_scaffold_6_GENE_51 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_52 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_53 GTP pyrophosphokinase [Signal transduction mechanisms]LeptoII_scaffold_6_GENE_54 ssDNA exonuclease [DNA replication, recombination, and repair]LeptoII_scaffold_6_GENE_55 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_56 protein export membrane protein, SecF [Intracellular trafficking and secretion]LeptoII_scaffold_6_GENE_57 protein-export membrane protein, SecD [Intracellular trafficking and secretion]LeptoII_scaffold_6_GENE_58 c hypo c hypo, possible preprotein translocase, YajC subunitLeptoII_scaffold_6_GENE_59 queuine tRNA-ribosyltransferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_6_GENE_60 arginyl tRNA synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_6_GENE_61 O-sialoglycoprotein endopeptidase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_6_GENE_62 ATP-dependant Clp protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_6_GENE_63 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_64 M23/M37 peptidase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_6_GENE_65 similar to T5 transposase-like transposaseLeptoII_scaffold_6_GENE_66 c hypo c hypoLeptoII_scaffold_6_GENE_67 hypo unique hypo unique

LeptoII_scaffold_6_GENE_68 T5 transposase-like transposaseLeptoII_scaffold_6_GENE_69 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_70 similar to T5 transposase-like transposaseLeptoII_scaffold_6_GENE_71 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_72 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_73 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_74 6-73=tRNA Val=6-74 isoleucyl tRNA synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_6_GENE_75 lipoprotein signal peptidase [Intracellular trafficking and secretion]LeptoII_scaffold_6_GENE_76 O-linked N-acetylglucosamine transferase [Carbohyhrate transport and metabolism]LeptoII_scaffold_6_GENE_77 pseudouridine synthase D, ribosomal subunit [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_6_GENE_78 c hypo c hypoLeptoII_scaffold_6_GENE_79 octaprenyl-diphosphate synthase [Coenzyme metabolism]LeptoII_scaffold_6_GENE_80 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_81 zinc metalloprotease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_6_GENE_82 inositol-1-monophosphatase [Carbohyhrate transport and metabolism]LeptoII_scaffold_6_GENE_83 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_84 c hypo c hypoLeptoII_scaffold_6_GENE_85 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_86 hypo unique hypo uniqueLeptoII_scaffold_6_GENE_87 UDP-3-O-acyl N-acetylglucosamine deacetylase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_6_GENE_88 hypo unique hypo unique

LeptoII-4: LeptoII_scaffold_659_GENE_1 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_659_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_659_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_659_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_659_GENE_5 T (single) transposase transposaseLeptoII_scaffold_955_GENE_1 T (single) transposase transposaseLeptoII_scaffold_955_GENE_2 T (single) transposase transposaseLeptoII_scaffold_955_GENE_3 ABC transporter ATP-binding protein [General function prediction only]LeptoII_scaffold_955_GENE_4 galactosyl-1-phosphate transferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_955_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_955_GENE_6 galactosyl-1-phosphate transferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_627_GENE_5 ABC transporter ATP-binding protein [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_627_GENE_4 ABC transporter permease protein [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_627_GENE_3 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_627_GENE_2 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_627_GENE_1 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_73_GENE_1 galactosyl-1-phosphate transferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_73_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_73_GENE_3 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_73_GENE_4 mannosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_73_GENE_5 T14 transposase transposaseLeptoII_scaffold_73_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_73_GENE_7 ATPase, AAA superfamily [General function prediction only]LeptoII_scaffold_73_GENE_8 T (single) transposase transposaseLeptoII_scaffold_73_GENE_9 ATPase, AAA superfamily [General function prediction only]LeptoII_scaffold_73_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_73_GENE_11 T (single) transposase transposaseLeptoII_scaffold_73_GENE_12 T (single) transposase transposaseLeptoII_scaffold_73_GENE_13 plasmid maintenance plasmid maintenance protein [Cell divison and chromosome partitioning]LeptoII_scaffold_73_GENE_14 plasmid maintenance plasmid maintenance system killer protein [Cell divison and chromosome partitioning]LeptoII_scaffold_73_GENE_15 T14 hypo unique transposase-like transposaseLeptoII_scaffold_73_GENE_16 hypo unique hypo uniqueLeptoII_scaffold_73_GENE_17 c hypo c hypoLeptoII_scaffold_73_GENE_18 c hypo c hypoLeptoII_scaffold_73_GENE_19 hypo unique hypo uniqueLeptoII_scaffold_73_GENE_20 hypo unique hypo uniqueLeptoII_scaffold_73_GENE_21 T (single) transposase transposaseLeptoII_scaffold_73_GENE_22 T (single) transposase transposaseLeptoII_scaffold_73_GENE_23 hypo unique hypo uniqueLeptoII_scaffold_73_GENE_24 T (single) transposase transposaseLeptoII_scaffold_73_GENE_25 c hypo c hypoLeptoII_scaffold_73_GENE_26 c hypo c hypo, possible hydrolaseLeptoII_scaffold_73_GENE_27 oxidoreductase/tartronic semialdehyde reductase [Lipid metabolism]LeptoII_scaffold_73_GENE_28 hypo unique hypo unique LeptoII_scaffold_73_GENE_29 unique hypo hypo unique - TPR domainLeptoII_scaffold_73_GENE_30 hypo unique hypo uniqueLeptoII_scaffold_73_GENE_31 hypo unique hypo uniqueLeptoII_scaffold_73_GENE_32 hypo unique hypo unique

LeptoII_scaffold_73_GENE_33 reverse transcriptase [DNA replication, recombination, and repair]LeptoII_scaffold_73_GENE_34 hypo unique hypo uniqueLeptoII_scaffold_73_GENE_35 T12 transposase transposaseLeptoII_scaffold_73_GENE_36 T9 transposase transposaseLeptoII_scaffold_73_GENE_37 T9 transposase (whole protein detected on 165-11 etc ) transposaseLeptoII_scaffold_73_GENE_38 T8 c hypo c hypo, transposase-like transposaseLeptoII_scaffold_73_GENE_39 T10 transposase transposaseLeptoII_scaffold_191_GENE_6 transketolase [Carbohyhrate transport and metabolism]LeptoII_scaffold_191_GENE_5 transaldolase [Carbohyhrate transport and metabolism]LeptoII_scaffold_191_GENE_4 glucose 6-phosphate dehydrogenase [Carbohyhrate transport and metabolism]LeptoII_scaffold_191_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_191_GENE_2 FAD binding monooxygenase [Coenzyme metabolism]LeptoII_scaffold_318_GENE_9 T (single) transposase transposaseLeptoII_scaffold_318_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_318_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_318_GENE_6 DNA methylation and regulatory protein, Ada [DNA replication, recombination, and repair]LeptoII_scaffold_318_GENE_5 methylated DNA-protein-cysteine S-methyltransferase [DNA replication, recombination, and repair]LeptoII_scaffold_318_GENE_4 T1 transposase transposaseLeptoII_scaffold_318_GENE_3 helix-turn-helix protein, CopG family [General function prediction only]LeptoII_scaffold_318_GENE_2 c hypo c hypoLeptoII_scaffold_318_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_13_GENE_1 T6 transposase transposaseLeptoII_scaffold_13_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_13_GENE_3 outer membrane Fe III dicitrate receptor [Inorganic ion transport and metabolism]LeptoII_scaffold_13_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_13_GENE_5 ADP-heptose-LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_13_GENE_6 c hypo c hypoLeptoII_scaffold_13_GENE_7 ADP-heptose-LPS heptosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_13_GENE_8 glycosyl transferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_13_GENE_9 c hypo c hypoLeptoII_scaffold_13_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_13_GENE_11 flagellar protein FliS [Cell motility and secretion]LeptoII_scaffold_13_GENE_12 flagellar hook-associated protein [Cell motility and secretion]LeptoII_scaffold_13_GENE_13 ab.ex. And Mem flagellin FliC-primary struct. Flagella [Cell motility and secretion]LeptoII_scaffold_13_GENE_14 c hypo c hypo - suspect flagella relatedLeptoII_scaffold_13_GENE_15 hypo unique hypo unique - suspect flagella relatedLeptoII_scaffold_13_GENE_16 flagellar hook associated protein, FlgL [Cell motility and secretion]LeptoII_scaffold_13_GENE_17 flagellar hook associated protein [Cell motility and secretion]LeptoII_scaffold_13_GENE_18 hypo unique hypo uniqueLeptoII_scaffold_13_GENE_19 hypo unique hypo unique - suspect flagella relatedLeptoII_scaffold_13_GENE_20 flagellin, FliC [Cell motility and secretion]LeptoII_scaffold_13_GENE_21 peptidase-likeLeptoII_scaffold_13_GENE_22 flagellar P-ring protein [Cell motility and secretion]LeptoII_scaffold_13_GENE_23 hypo unique hypo unique - suspect flagellar related LeptoII_scaffold_13_GENE_24 hypo unique hypo uniqueLeptoII_scaffold_13_GENE_25 flagellar hook basal-body protein FlgG [Cell motility and secretion]LeptoII_scaffold_13_GENE_26 flagellar hook protein FlgG [Cell motility and secretion]LeptoII_scaffold_13_GENE_27 catechol pathway acid hydratase [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_13_GENE_28 dihydrodipicolinate reductase [Amino acid transport and metabolism]LeptoII_scaffold_13_GENE_29 dihydrodipicolinate synthase [Amino acid transport and metabolism]LeptoII_scaffold_13_GENE_30 hypo unique hypo unique - suspect lysine biosynthesisLeptoII_scaffold_13_GENE_31 diaminopimelate decarboxylase [Amino acid transport and metabolism]LeptoII_scaffold_13_GENE_32 arginosuccinate lyase [Amino acid transport and metabolism]LeptoII_scaffold_13_GENE_33 arginosuccinate synthase [Amino acid transport and metabolism]LeptoII_scaffold_13_GENE_34 ornithine carbamoyltransferase [Amino acid transport and metabolism]LeptoII_scaffold_13_GENE_35 acetylornithine aminotransferase [Amino acid transport and metabolism]LeptoII_scaffold_13_GENE_36 potassium uptake protein [Inorganic ion transport and metabolism]LeptoII_scaffold_13_GENE_37 permease [Inorganic ion transport and metabolism]LeptoII_scaffold_13_GENE_38 hypo unique hypo uniqueLeptoII_scaffold_13_GENE_39 hypo unique hypo uniqueLeptoII_scaffold_13_GENE_40 hypo unique hypo uniqueLeptoII_scaffold_13_GENE_41 4-hydroxybenzoate polyprenyltransferase [Coenzyme metabolism]LeptoII_scaffold_13_GENE_42 hypo unique hypo unique - suspect ubiquinone biosynthesis relatedLeptoII_scaffold_13_GENE_43 Fe-S oxidoreductase [Energy production and conversion]LeptoII_scaffold_13_GENE_44 ubiquinone/menaquinone biosynthesis methyltransferase [Coenzyme metabolism]LeptoII_scaffold_13_GENE_45 hypo unique hypo unique - suspect ubiquinone biosynthesis relatedLeptoII_scaffold_13_GENE_46 exopolyphosphatase [Nucleotide transport and metabolism]LeptoII_scaffold_13_GENE_47 thymidylate kinase [Nucleotide transport and metabolism]LeptoII_scaffold_13_GENE_48 thymidylate kinase [Nucleotide transport and metabolism]LeptoII_scaffold_13_GENE_49 possible exochitinase I precursor

LeptoII_scaffold_13_GENE_50 ribose-5-phosphate isomerase [Carbohyhrate transport and metabolism]LeptoII_scaffold_13_GENE_51 glycine hydroxymethyltransferase GlyA [Carbohyhrate transport and metabolism]LeptoII_scaffold_13_GENE_52 4-hydroxybenzoate octaprenyltransferase UbiA [Coenzyme metabolism]LeptoII_scaffold_13_GENE_53 primosomal protein N' PriA (replication factor/helicase) [DNA replication, recombination, and repair]LeptoII_scaffold_13_GENE_54 Zn-dependant protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_13_GENE_55 geranylgeranyl reductase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_13_GENE_56 cytochrome c biogenesis protein CcdA [Coenzyme metabolism]LeptoII_scaffold_13_GENE_57 hypo unique hypo uniqueLeptoII_scaffold_13_GENE_58 thiol:disulfide interchange protein tlpA/cytochrome c biogenesis [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_13_GENE_59 cytochrome c biogenesis protein CcmF/ABC transporter [Coenzyme metabolism]LeptoII_scaffold_13_GENE_60 cytochrome biosynthesis protein Ccs1/ResB [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_13_GENE_61 ABC transporter, solute-binding periplasmic protein [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_13_GENE_62 ABC transporter, ATP-binding protein [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_13_GENE_63 ABC transporter, permease protein [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_13_GENE_64 alanine racemase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_13_GENE_65 ribosome recycling factor [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_13_GENE_66 uridylate kinase [Nucleotide transport and metabolism]LeptoII_scaffold_13_GENE_67 translation elongation factor EF-Ts [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_13_GENE_68 ribosomal protein S2 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_426_GENE_6 N-acetylglutamate synthase [Amino acid transport and metabolism]LeptoII_scaffold_426_GENE_5 N-acetylglutamate semialdehyde dehydrogenase [Amino acid transport and metabolism]LeptoII_scaffold_426_GENE_4 ribosomal protein S9 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_426_GENE_3 ribosomal protein L13 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_426_GENE_2 Fe-S oxidoreductase/methyltransferase [Energy production and conversion]LeptoII_scaffold_426_GENE_1 ferredoxin [Energy production and conversion]

LeptoII-5: LeptoII_scaffold_21_GENE_1 T6 transposase transposaseLeptoII_scaffold_21_GENE_2 c hypo c hypo LeptoII_scaffold_21_GENE_3 c hypo c hypoLeptoII_scaffold_21_GENE_4 c hypo c hypo resolvase relatedLeptoII_scaffold_21_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_6 integrase INT P22C/p4 integrase [DNA replication, recombination, and repair]LeptoII_scaffold_21_GENE_7 21-7=tRNA Arg=21-8 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_8 leucyl tRNA synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_21_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_10 hypo unique hypo unique (like DNA polymerase III, beta subunit)LeptoII_scaffold_21_GENE_11 hypo unique hypo unique, possible ribosomal protein S20LeptoII_scaffold_21_GENE_12 resembles virulence factor c hypo c hypo (similar to virulence factor MviN)LeptoII_scaffold_21_GENE_13 HNH endonuclease [Defense mechanisms]LeptoII_scaffold_21_GENE_14 c hypo c hypoLeptoII_scaffold_21_GENE_15 c hypo c hypoLeptoII_scaffold_21_GENE_16 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_17 c hypo c hypo (like ATPase of the PP-loop superfamily)LeptoII_scaffold_21_GENE_18 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_19 HD-GYP domain response regulator [Signal transduction mechanisms]LeptoII_scaffold_21_GENE_20 21-20=tRNA His=21-21 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_21 anthranilate synthase component [Amino acid transport and metabolism]LeptoII_scaffold_21_GENE_22 branched-chain amino acid aminotransferase [Amino acid transport and metabolism]LeptoII_scaffold_21_GENE_23 rubrerythrin (antioxidant) - abundant membrane protein [Defense mechanisms]LeptoII_scaffold_21_GENE_24 riboncleotide-diphosphate reductase [Nucleotide transport and metabolism]LeptoII_scaffold_21_GENE_25 c hypo c hypoLeptoII_scaffold_21_GENE_26 c hypo c hypoLeptoII_scaffold_21_GENE_27 cation efflux transporter involved in multidrug resistance [Defense mechanisms]LeptoII_scaffold_21_GENE_28 cation efflux system protein involved in multidrug resistance [Defense mechanisms]LeptoII_scaffold_21_GENE_29 21-29=tRNA Arg=21-30 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_30 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_31 21-31=tRNA Cys=21-32 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_32 proline betaine transporter [Carbohyhrate transport and metabolism]LeptoII_scaffold_21_GENE_33 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_34 L-2,4-diaminobutyric acid acetyltransferase [Amino acid transport and metabolism]LeptoII_scaffold_21_GENE_35 diaminobutyrate pyruvate aminotransferase [Amino acid transport and metabolism]LeptoII_scaffold_21_GENE_36 ectoine synthase [Amino acid transport and metabolism]LeptoII_scaffold_21_GENE_37 L-proline 4-hydroxylase [Amino acid transport and metabolism]LeptoII_scaffold_21_GENE_38 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_39 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_40 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_41 Ca++/Na+ antiporter [Inorganic ion transport and metabolism]LeptoII_scaffold_21_GENE_42 major facilitator family permease [General function prediction only]LeptoII_scaffold_21_GENE_43 c hypo c hypoLeptoII_scaffold_21_GENE_44 c hypo c hypo

LeptoII_scaffold_21_GENE_45 20S proteasome, alpha subunit [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_21_GENE_46 20S proteasome, beta subunit [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_21_GENE_47 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_48 c hypo c hypoLeptoII_scaffold_21_GENE_49 AAA family ATPase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_21_GENE_50 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_51 bacterioferritin comigratory protein/peroxiredoxin [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_21_GENE_52 membrane protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_21_GENE_53 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_54 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_55 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_56 hypo unique hypo uniqueLeptoII_scaffold_21_GENE_57 Zn-dependent alcohol dehydrogenase [General function prediction only]LeptoII_scaffold_21_GENE_58 c hypo c hypo (rhodanese-related sulfurtransferase-like)LeptoII_scaffold_21_GENE_59 cation efflux pump for multidrug resistance [Defense mechanisms]LeptoII_scaffold_21_GENE_60 efflux transporter for multidrug resistance [Defense mechanisms]LeptoII_scaffold_32_GENE_52 outer membrane efflux protein [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_32_GENE_51 transcriptional regulator [Transcription]LeptoII_scaffold_32_GENE_50 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_49 excinuclease ABC, subunit B [DNA replication, recombination, and repair]LeptoII_scaffold_32_GENE_48 c hypo c hypoLeptoII_scaffold_32_GENE_47 hypo unique hypo unique (like molybdenum cofactor carrier protein)LeptoII_scaffold_32_GENE_46 aminopeptidase [Amino acid transport and metabolism]LeptoII_scaffold_32_GENE_45 thioldisulfide isomerase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_32_GENE_44 endonuclease [Lipid metabolism]LeptoII_scaffold_32_GENE_43 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_42 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_41 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_32_GENE_40 cation transport ATPase [Inorganic ion transport and metabolism]LeptoII_scaffold_32_GENE_39 ammonium transporter AMT2 [Inorganic ion transport and metabolism]LeptoII_scaffold_32_GENE_38 N-regulatory protein PII (Gln synthetase regulator) [Amino acid transport and metabolism]LeptoII_scaffold_32_GENE_37 ammonia permease [Inorganic ion transport and metabolism]LeptoII_scaffold_32_GENE_36 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_35 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_34 methionine gamma lyase [Amino acid transport and metabolism]LeptoII_scaffold_32_GENE_33 c hypo c hypo, GGDEF domain proteinLeptoII_scaffold_32_GENE_32 peptide ABC transporter [Amino acid transport and metabolism]LeptoII_scaffold_32_GENE_31 peptide ABC transporter [Amino acid transport and metabolism]LeptoII_scaffold_32_GENE_30 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_29 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_28 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_27 hypo unique hypo unique (contains domain found in small soluble proteinsLeptoII_scaffold_32_GENE_26 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_25 c hypo c hypoLeptoII_scaffold_32_GENE_24 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_23 hydrolase/phosphoglycolate phosphatase [General function prediction only]LeptoII_scaffold_32_GENE_22 hexapeptide transferase [General function prediction only]LeptoII_scaffold_32_GENE_21 sensor histidine kinase [Signal transduction mechanisms]LeptoII_scaffold_32_GENE_20 sigma 54 dependent DNA-binding response regulator [Signal transduction mechanisms]LeptoII_scaffold_32_GENE_19 serine protease, abundant, extracellular [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_32_GENE_18 Holliday junction resolvase [DNA replication, recombination, and repair]LeptoII_scaffold_32_GENE_17 Holliday junction helicase [DNA replication, recombination, and repair]LeptoII_scaffold_32_GENE_16 Holliday junction helicase [DNA replication, recombination, and repair]LeptoII_scaffold_32_GENE_15 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_14 periplasmic serine protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_32_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_11 c hypo c hypoLeptoII_scaffold_32_GENE_10 c hypo c hypoLeptoII_scaffold_32_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_8 TRAP signal transduction protein [Signal transduction mechanisms]LeptoII_scaffold_32_GENE_7 tRNA(5-methylaminomethyl-2-thiouridylate)-methyltransferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_32_GENE_6 c hypo c hypo similar to Fe-S oxidoreductaseLeptoII_scaffold_32_GENE_5 c hypo c hypoLeptoII_scaffold_32_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_3 heterdisulfide reductase [Coenzyme metabolism]LeptoII_scaffold_32_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_32_GENE_1 major facilitator family permease [General function prediction only]

LeptoII-6: LeptoII_scaffold_23_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_23_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_23_GENE_3 glutamine synthetase [Amino acid transport and metabolism]LeptoII_scaffold_23_GENE_4 aspartyl tRNA synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_23_GENE_5 pseudouridine synthase B found in alternative reading frameLeptoII_scaffold_23_GENE_6 GMP synthase [Nucleotide transport and metabolism]LeptoII_scaffold_23_GENE_7 inosine monophosphate dehydrogenase [Nucleotide transport and metabolism]LeptoII_scaffold_23_GENE_8 c hypo c hypoLeptoII_scaffold_23_GENE_9 ATPase with chaperone activity, ATP-binding domain [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_23_GENE_10 ATP-dependent Lon protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_23_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_23_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_23_GENE_13 DNA ligase [DNA replication, recombination, and repair]LeptoII_scaffold_23_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_23_GENE_15 hypo unique hypo uniqueLeptoII_scaffold_23_GENE_16 apolipoprotein N-acetyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_23_GENE_17 peptide chain release factor [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_23_GENE_18 heat shock protein [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_23_GENE_19 ATP-dependent protease La [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_23_GENE_20 endonuclease III [DNA replication, recombination, and repair]LeptoII_scaffold_23_GENE_21 c hypo c hypoLeptoII_scaffold_23_GENE_22 aldo/keto reductase [General function prediction only]LeptoII_scaffold_23_GENE_23 transcriptional regulator [Transcription]LeptoII_scaffold_23_GENE_24 glucoamylase [Carbohyhrate transport and metabolism]LeptoII_scaffold_23_GENE_25 histidyl tRNA synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_23_GENE_26 hypo unique hypo uniqueLeptoII_scaffold_23_GENE_27 glucoamylase [Carbohyhrate transport and metabolism]LeptoII_scaffold_23_GENE_28 GTP-binding protein, LepA [Intracellular trafficking and secretion]LeptoII_scaffold_23_GENE_29 signal peptidase I [Intracellular trafficking and secretion]LeptoII_scaffold_23_GENE_30 ADP-heptose synthase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_23_GENE_31 3-deoxy-D-manno-octylosonate cytidylyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_23_GENE_32 CTP synthetase [Nucleotide transport and metabolism]LeptoII_scaffold_23_GENE_33 2-dehydro-3-deoxyphosphooctonate aldolase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_23_GENE_34 sugar isomerase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_23_GENE_35 phosphatase/phosphatidyl transferase [General function prediction only]LeptoII_scaffold_23_GENE_36 CDP-diacylglycerol-glycerol-3-phosphate 3-phosphatidyltransferase [Lipid metabolism]LeptoII_scaffold_23_GENE_37 c hypo c hypoLeptoII_scaffold_23_GENE_38 hypo unique hypo uniqueLeptoII_scaffold_23_GENE_39 cell wall endopeptidase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_23_GENE_40 two-component sensor histidine kinase [Signal transduction mechanisms]LeptoII_scaffold_23_GENE_41 hypo unique hypo uniqueLeptoII_scaffold_23_GENE_42 transcriptional regulator [Signal transduction mechanisms]LeptoII_scaffold_23_GENE_43 c hypo c hypoLeptoII_scaffold_23_GENE_44 c hypo c hypoLeptoII_scaffold_23_GENE_45 small conductance mechanosensitive ion channel [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_23_GENE_46 hypo unique hypo uniqueLeptoII_scaffold_23_GENE_47 phosphatidylglycerophosphate B [Lipid metabolism]LeptoII_scaffold_23_GENE_48 radical SAM enzyme/Fe-S redox protein [Energy production and conversion]LeptoII_scaffold_23_GENE_49 hypo unique hypo uniqueLeptoII_scaffold_23_GENE_50 hypo unique hypo unique (like oxidoreductase/dioxygenase)LeptoII_scaffold_23_GENE_51 c hypo c hypoLeptoII_scaffold_23_GENE_52 hypo unique hypo uniqueLeptoII_scaffold_23_GENE_53 cytochrome c oxidase, cbb3 type, subunit I [Energy production and conversion]LeptoII_scaffold_33_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_4 hypo unique hypo unique (like Sec independent protein secretion component)LeptoII_scaffold_33_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_6 FAD-dependent oxidreductase [Energy production and conversion]LeptoII_scaffold_33_GENE_7 transporter/permease [General function prediction only]LeptoII_scaffold_33_GENE_8 NADH:flavin oxidoreductase/xenobiotic reductase [Energy production and conversion]LeptoII_scaffold_33_GENE_9 multidrug resistance transporter [Defense mechanisms]LeptoII_scaffold_33_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_12 c hypo c hypoLeptoII_scaffold_33_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_15 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_33_GENE_16 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_33_GENE_17 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_18 possible serine endoproteaseLeptoII_scaffold_33_GENE_19 hypo unique hypo unique

LeptoII_scaffold_33_GENE_20 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_21 nodulation protein NfeD [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_33_GENE_22 Band 7 protein [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_33_GENE_23 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_24 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_25 oxidoreductase [General function prediction only]LeptoII_scaffold_33_GENE_26 acyl transferase [Lipid metabolism]LeptoII_scaffold_33_GENE_27 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_28 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_29 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_30 sigma 54 dependent DNA-binding response regulator [Signal transduction mechanisms]LeptoII_scaffold_33_GENE_31 sensory box histidine kinase [Signal transduction mechanisms]LeptoII_scaffold_33_GENE_32 c hypo c hypoLeptoII_scaffold_33_GENE_33 NADH dehydrogenase, subunit F [Energy production and conversion]LeptoII_scaffold_33_GENE_34 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_35 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_36 dihydroxyacid dehydratase [Amino acid transport and metabolism]LeptoII_scaffold_33_GENE_37 translation factor sua5-like [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_33_GENE_38 dihydroxyacid dehydratase [Amino acid transport and metabolism]LeptoII_scaffold_33_GENE_39 c hypo c hypoLeptoII_scaffold_33_GENE_40 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_41 c hypo c hypoLeptoII_scaffold_33_GENE_42 NADH dehydrogenase, subunit 5 [Energy production and conversion]LeptoII_scaffold_33_GENE_43 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_46 hypo unique hypo uniqueLeptoII_scaffold_33_GENE_47 glycosyl transferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_33_GENE_48 glycosyl transferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_33_GENE_49 proline oxidase [Amino acid transport and metabolism]

[Cell envelope biogenesis, outer membrane]LeptoII-7: LeptoII_scaffold_51_GENE_27 hypo unique hypo unique

LeptoII_scaffold_51_GENE_26 c hypo c hypoLeptoII_scaffold_51_GENE_25 hypo unique hypo uniqueLeptoII_scaffold_51_GENE_24 hypo unique hypo unique (sim. to iron(III) dicitrate transport protein)LeptoII_scaffold_51_GENE_23 biopolymer export protein, ExbB [Intracellular trafficking and secretion]LeptoII_scaffold_51_GENE_22 TonB system transport protein, ExbD [Intracellular trafficking and secretion]LeptoII_scaffold_51_GENE_21 TonB [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_51_GENE_20 hypo unique hypo uniqueLeptoII_scaffold_51_GENE_19 two component response regulator/transcriptional regulator [Signal transduction mechanisms]LeptoII_scaffold_51_GENE_18 c hypo c hypoLeptoII_scaffold_51_GENE_17 exodeoxyribonuclease V, alpha subunit [DNA replication, recombination, and repair]LeptoII_scaffold_51_GENE_16 exodeoxyribonuclease V, beta subunit [DNA replication, recombination, and repair]LeptoII_scaffold_51_GENE_15 exodeoxyribonuclease V, gamma subunit/RecC [DNA replication, recombination, and repair]LeptoII_scaffold_51_GENE_14 Zn-dependent alcohol dehydrogenase [General function prediction only]LeptoII_scaffold_51_GENE_13 multiple antibiotic resistance MarR regulator [Transcription]LeptoII_scaffold_51_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_51_GENE_11 outer membrane efflux protein [Defense mechanisms]LeptoII_scaffold_51_GENE_10 multidrug efflux transporter [Defense mechanisms]LeptoII_scaffold_51_GENE_9 multidrug efflux transporter [Defense mechanisms]LeptoII_scaffold_51_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_51_GENE_7 c hypo c hypoLeptoII_scaffold_51_GENE_6 51-5=tRNA Lys=51-6 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_51_GENE_5 NADP-reducing hydrogenase, subunit C/NADH dehydrogenase [Energy production and conversion]LeptoII_scaffold_51_GENE_4 T6 transposase transposaseLeptoII_scaffold_51_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_51_GENE_2 c hypo c hypoLeptoII_scaffold_51_GENE_1 hypo unique hypo uniquealternatively to 798 or 435 14-2=tRNA Lys=14-3LeptoII_scaffold_14_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_6 type III restriction modification system methylase [DNA replication, recombination, and repair]LeptoII_scaffold_14_GENE_7 competence factor ComA competence factor ComA [General function prediction only]LeptoII_scaffold_14_GENE_8 phosphoglucosamine mutase [Carbohyhrate transport and metabolism]LeptoII_scaffold_14_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_10 transcriptional regulator [Transcription]LeptoII_scaffold_14_GENE_11 NADH:flavin oxidoreductase [Energy production and conversion]LeptoII_scaffold_14_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_13 peptidoglycan associated lipoprotein [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_14_GENE_14 c hypo c hypoLeptoII_scaffold_14_GENE_15 c hypo c hypoLeptoII_scaffold_14_GENE_16 FilB, ABC transporter ATP-binding protein [Cell motility and secretion]

LeptoII_scaffold_14_GENE_17 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_18 c hypo c hypoLeptoII_scaffold_14_GENE_19 two component response regulator [Signal transduction mechanisms]LeptoII_scaffold_14_GENE_20 hypo unique hypo unique, similar to Fe/Pb permeases, cytochrome c (cty579) [Energy production and conversion]LeptoII_scaffold_14_GENE_21 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_22 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_23 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_24 enolase [Carbohyhrate transport and metabolism]LeptoII_scaffold_14_GENE_25 cytochrome c nitrite reductase [Energy production and conversion]LeptoII_scaffold_14_GENE_26 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_27 glutamyl tRNA (Gln) amidotransferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_14_GENE_28 glutamyl tRNA amidotransferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_14_GENE_29 aspartate decarboxylase [Coenzyme metabolism]LeptoII_scaffold_14_GENE_30 glutamyl-tRNA amidotransferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_14_GENE_31 ATP-dependent DNA helicase [DNA replication, recombination, and repair]LeptoII_scaffold_14_GENE_32 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_33 Glucosamine-fructose-6-phosphate aminotransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_14_GENE_34 UDP-N-acetylglucosamine pyrophosphorylase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_14_GENE_35 transporter [General function prediction only]LeptoII_scaffold_14_GENE_36 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_37 lactoylglutathione lyase [Amino acid transport and metabolism]LeptoII_scaffold_14_GENE_38 transcriptional regulator in arsenic resistance operon [Transcription]LeptoII_scaffold_14_GENE_39 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_40 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_41 transcriptional regulator [Transcription]LeptoII_scaffold_14_GENE_42 c hypo c hypo (faint similarity to glutamate synthase)LeptoII_scaffold_14_GENE_43 c hypo c hypoLeptoII_scaffold_14_GENE_44 transcriptional regulator MarR [Transcription]LeptoII_scaffold_14_GENE_45 fuculose-1-phosphate aldolase [Carbohyhrate transport and metabolism]LeptoII_scaffold_14_GENE_46 methylthioribose phosphatase [Amino acid transport and metabolism]LeptoII_scaffold_14_GENE_47 RuBisCO [Carbohyhrate transport and metabolism]LeptoII_scaffold_14_GENE_48 oxidase [General function prediction only]LeptoII_scaffold_14_GENE_49 peroxiredoxin [Defense mechanisms]LeptoII_scaffold_14_GENE_50 cytochrome c peroxidase [Defense mechanisms]LeptoII_scaffold_14_GENE_51 transcriptional regulator [Transcription]LeptoII_scaffold_14_GENE_52 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_53 thymidylate kinase [Nucleotide transport and metabolism]LeptoII_scaffold_14_GENE_54 DNA polymerase III [DNA replication, recombination, and repair]LeptoII_scaffold_14_GENE_55 signal peptidase II [Intracellular trafficking and secretion]LeptoII_scaffold_14_GENE_56 methionyl tRNA synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_14_GENE_57 DNase TatD [DNA replication, recombination, and repair]LeptoII_scaffold_14_GENE_58 c hypo c hypoLeptoII_scaffold_14_GENE_59 c hypo c hypoLeptoII_scaffold_14_GENE_60 amino acid permease [Amino acid transport and metabolism]LeptoII_scaffold_14_GENE_61 glycoprotein [General function prediction only]LeptoII_scaffold_14_GENE_62 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_63 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_64 hypo unique hypo uniqueLeptoII_scaffold_14_GENE_65 Pili-associated adhesion pili-associated adhesion protein [General function prediction only]LeptoII_scaffold_14_GENE_66 amino acid transporter [Amino acid transport and metabolism]LeptoII_scaffold_14_GENE_67 NADH dehydrogenase FAD subunit [Energy production and conversion]LeptoII_scaffold_14_GENE_68 cytosine permease [Nucleotide transport and metabolism]

LeptoII-8: LeptoII_scaffold_88_GENE_20 hypo unique hypo uniqueLeptoII_scaffold_88_GENE_19 ribosomal protein L15 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_88_GENE_18 preprotein translocase, SecY subunit [Intracellular trafficking and secretion]LeptoII_scaffold_88_GENE_17 adenylate kinase [Nucleotide transport and metabolism]LeptoII_scaffold_88_GENE_16 methionine aminopeptidase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_88_GENE_15 ribosomal protein S4P [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_88_GENE_14 RNA polymerase [Transcription]LeptoII_scaffold_88_GENE_13 ribosomal protein L17 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_88_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_88_GENE_11 dTDP-4-dehydrorhamnose reductase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_88_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_88_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_88_GENE_8 trehalose-phosphate synthase [Carbohyhrate transport and metabolism]LeptoII_scaffold_88_GENE_7 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_88_GENE_6 macrolide efflux protein [Defense mechanisms]LeptoII_scaffold_88_GENE_5 macrolide efflux protein [Defense mechanisms]LeptoII_scaffold_88_GENE_4 ADP-L-glycero-D-manno-heptose-6-epimerase [Cell envelope biogenesis, outer membrane]

LeptoII_scaffold_88_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_30_GENE_1 amidophosphoribosyltransferase PurF [Nucleotide transport and metabolism]LeptoII_scaffold_30_GENE_2 phosphoribosylformylglycinamidine synthase, PurL [Nucleotide transport and metabolism]LeptoII_scaffold_30_GENE_3 phosphoribosylformylglycinamidine synthase (fragment, delete?) [Nucleotide transport and metabolism]LeptoII_scaffold_30_GENE_4 phosphoribosylformylglycinamidine synthase PurM [Nucleotide transport and metabolism]LeptoII_scaffold_30_GENE_5 c hypo c hypoLeptoII_scaffold_30_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_30_GENE_7 transcriptional regulator [Transcription]LeptoII_scaffold_30_GENE_8 outer membrane efflux protein involved in multidrug resistance [Defense mechanisms]LeptoII_scaffold_30_GENE_9 efflux transporter involved in multidrug resistance [Defense mechanisms]LeptoII_scaffold_30_GENE_10 cation efflux protein involved in multidrug resistance [Defense mechanisms]LeptoII_scaffold_30_GENE_11 transcriptional regulator [Transcription]LeptoII_scaffold_30_GENE_12 outer membrane efflux protein [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_30_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_30_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_30_GENE_15 ABC transporter ATP-binding protein for multidrug resistance [Defense mechanisms]LeptoII_scaffold_30_GENE_16 ABC transporter permease protein for multidrug resistance [Defense mechanisms]LeptoII_scaffold_30_GENE_17 phenol hydroxylase [Energy production and conversion]LeptoII_scaffold_30_GENE_18 hypo unique hypo uniqueLeptoII_scaffold_30_GENE_19 possible 3-hydroxybutyryl-coA dehydrogenase [Lipid metabolism]LeptoII_scaffold_30_GENE_20 hypo unique hypo uniqueLeptoII_scaffold_30_GENE_21 hypo unique hypo uniqueLeptoII_scaffold_30_GENE_22 c hypo c hypoLeptoII_scaffold_30_GENE_23 pleiotropic regulatory protein [General function prediction only]LeptoII_scaffold_30_GENE_24 c hypo c hypoLeptoII_scaffold_30_GENE_25 dethiobiotin synthetase [Coenzyme metabolism]LeptoII_scaffold_30_GENE_26 hypo unique hypo uniqueLeptoII_scaffold_30_GENE_27 hypo unique hypo unique fatty acid protein (cleavage of one carboxyl of acetyl coALeptoII_scaffold_30_GENE_28 hypo unique hypo unique carboxylic acid and cleaves CO2 to get NADH, requires LeptoII_scaffold_30_GENE_29 hypo unique hypo uniqueLeptoII_scaffold_30_GENE_30 hypo unique hypo uniqueLeptoII_scaffold_30_GENE_31 sensory transduction histidine kinase [Signal transduction mechanisms]LeptoII_scaffold_30_GENE_32 two-component response regulator CheY [Signal transduction mechanisms]LeptoII_scaffold_30_GENE_33 sensory box/EAL domain/GGDEF domain [Signal transduction mechanisms]LeptoII_scaffold_30_GENE_34 thiamine phosphate synthase (pyrophosphorylase) ThiE [Coenzyme metabolism]LeptoII_scaffold_30_GENE_35 biotin carboxylase [Lipid metabolism]LeptoII_scaffold_30_GENE_36 acetyl-CoA carboxylase/biotin carboxyl carrier protein [Lipid metabolism]LeptoII_scaffold_30_GENE_37 translation elongation factor [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_30_GENE_38 3-dehydroquinate dehydratase, type II [Amino acid transport and metabolism]LeptoII_scaffold_30_GENE_39 c hypo c hypoLeptoII_scaffold_30_GENE_40 flavoprotein affecting synthesis of DNA and pantothenate metabol [Coenzyme metabolism]LeptoII_scaffold_30_GENE_41 hypo unique hypo uniqueLeptoII_scaffold_30_GENE_42 guanylate kinase [Nucleotide transport and metabolism]LeptoII_scaffold_30_GENE_43 c hypo c hypoLeptoII_scaffold_30_GENE_44 c hypo c hypoLeptoII_scaffold_30_GENE_45 glycogen debranching enzyme [Carbohyhrate transport and metabolism]LeptoII_scaffold_30_GENE_46 cell division protein FtsI [Cell divison and chromosome partitioning]LeptoII_scaffold_317_GENE_7 2nd by cov. inosine monophosphate dehydrogenase (purine biosy[Nucleotide transport and metabolism]LeptoII_scaffold_317_GENE_6 8-amino-7-oxononanoate synthase [Coenzyme metabolism]LeptoII_scaffold_317_GENE_5 6-carboxyhexanoate-CoA ligase [Coenzyme metabolism]LeptoII_scaffold_317_GENE_4 biotin synthetase [Coenzyme metabolism]LeptoII_scaffold_317_GENE_3 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_94_GENE_22 T5 transposase transposaseLeptoII_scaffold_94_GENE_21 T5 transposase transposaseLeptoII_scaffold_94_GENE_20 glycyl-tRNA synthetase, alpha subunit [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_94_GENE_19 glycyl-tRNA synthetase, beta subunit [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_94_GENE_18 riboflavin biosynthesis protein RibD [Coenzyme metabolism]LeptoII_scaffold_94_GENE_17 riboflavin synthase, alpha chain [Coenzyme metabolism]LeptoII_scaffold_94_GENE_16 c hypo c hypoLeptoII_scaffold_94_GENE_15 precorrin-2 C20-methyltransferase, CobI [Coenzyme metabolism]LeptoII_scaffold_94_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_94_GENE_13 cobalamin biosynthesis precorrin-3 methylase, CobM [Coenzyme metabolism]LeptoII_scaffold_94_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_94_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_94_GENE_10 Mg-protoporphyrin IX monomethyl ester oxidative cyclase [Coenzyme metabolism]LeptoII_scaffold_94_GENE_9 cation efflux system protein for Zn/Cd/Co, magnetosome protein M[Inorganic ion transport and metabolism]LeptoII_scaffold_94_GENE_8 c hypo c hypoLeptoII_scaffold_94_GENE_7 DNA recombination protein RmuC [DNA replication, recombination, and repair]LeptoII_scaffold_94_GENE_6 dihydroxy acid dehydratase [Amino acid transport and metabolism]LeptoII_scaffold_94_GENE_5 hypo unique hypo unique

LeptoII_scaffold_94_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_94_GENE_3 cobyric acid synthase, CobQ [Coenzyme metabolism]LeptoII_scaffold_94_GENE_2 cobalamin biosynthesis protein, CobD [Coenzyme metabolism]LeptoII_scaffold_94_GENE_1 histidinol phosphate aminotransferase, CobC [Amino acid transport and metabolism]

LeptoII-9: LeptoII_scaffold_135_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_135_GENE_2 GTP-binding protein [General function prediction only]LeptoII_scaffold_135_GENE_3 phosphoenolpyruvate synthase [Carbohyhrate transport and metabolism]LeptoII_scaffold_135_GENE_4 AAA-type ATPase/response regulator [Signal transduction mechanisms]LeptoII_scaffold_135_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_135_GENE_6 amino-acid acetyltransferase [Amino acid transport and metabolism]LeptoII_scaffold_135_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_135_GENE_8 methyl-accepting chemotaxis protein [Cell motility and secretion / Intracellular trafficking and secretLeptoII_scaffold_135_GENE_9 c hypo c hypo, similar to methyltransferaseLeptoII_scaffold_135_GENE_10 short chain dehydrogenae/oxidoreductase [General function prediction only]LeptoII_scaffold_135_GENE_11 glucose-6-phosphate dehydrogenase [Carbohyhrate transport and metabolism]LeptoII_scaffold_135_GENE_12 6-phosphogluconate dehydrogenase [Carbohyhrate transport and metabolism]LeptoII_scaffold_295_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_295_GENE_4 295-3=tRNA Ala =295-4 phosphoribosylglycinamide formyltransferase [Nucleotide transport and metabolism]LeptoII_scaffold_295_GENE_5 phosphoribosylformylglycinamidine cyclo-ligase [Nucleotide transport and metabolism]LeptoII_scaffold_295_GENE_6 cell wall surface anchor [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_295_GENE_7 hypo unique hypo unique found in alternative reading frameLeptoII_scaffold_295_GENE_8 ribonuclease III [Transcription]LeptoII_scaffold_295_GENE_9 beta-ketoacyl-acyl carrier protein synthase II fabF [Lipid metabolism]LeptoII_scaffold_295_GENE_10 acyl-carrier protein [Lipid metabolism]LeptoII_scaffold_295_GENE_11 acyl carrier protein [Lipid metabolism]LeptoII_scaffold_27_GENE_2 malonyl-coA acyl carrier proteintransacylase fabD [Lipid metabolism]LeptoII_scaffold_27_GENE_3 beta-ketoacyl-[ACP] synthase III fabHA? [Lipid metabolism]LeptoII_scaffold_27_GENE_4 phosholipid synthesis protein PlsX [Lipid metabolism]LeptoII_scaffold_27_GENE_5 hypo unique hypo unique, possible ribosomal protein L32LeptoII_scaffold_27_GENE_6 c hypo c hypoLeptoII_scaffold_27_GENE_7 prolyl tRNA synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_27_GENE_8 peptidoglycan acylation [Lipid metabolism]LeptoII_scaffold_27_GENE_9 zinc metallopeptidase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_27_GENE_10 1-deoxy-D-xylulose 5-phosphate reductoisomerase [Lipid metabolism]LeptoII_scaffold_27_GENE_11 phosphatidate cytidylyltransferase [Lipid metabolism]LeptoII_scaffold_27_GENE_12 undecaprenyl pyrophosphate synthase [Lipid metabolism]LeptoII_scaffold_27_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_27_GENE_14 formate-tetrahydrofolate ligase [Nucleotide transport and metabolism]LeptoII_scaffold_27_GENE_15 undecaprenyl kinase involved in antibiotic resistance [Defense mechanisms]LeptoII_scaffold_27_GENE_16 Sec independent protein translocase [Intracellular trafficking and secretion]LeptoII_scaffold_27_GENE_17 hypo unique hypo uniqueLeptoII_scaffold_27_GENE_18 hypo unique hypo uniqueLeptoII_scaffold_27_GENE_19 ribosomal-protein-alanine acetyltransferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_27_GENE_20 glycoprotein endopeptidase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_27_GENE_21 DNA repair protein RadA [DNA replication, recombination, and repair]LeptoII_scaffold_27_GENE_22 hypo unique hypo uniqueLeptoII_scaffold_27_GENE_23 c hypo c hypo, possible lysine decarboxylase/nucleotide binding proteinLeptoII_scaffold_27_GENE_24 PmbA protein, protease/DNA gyrase modulator [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_27_GENE_25 TldD protein, protease/DNA gyrase modulator [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_27_GENE_26 beta-lactamase [Defense mechanisms]LeptoII_scaffold_27_GENE_27 phytoene synthase [Lipid metabolism]LeptoII_scaffold_27_GENE_28 phytoene dehydrogenase [Coenzyme metabolism]LeptoII_scaffold_27_GENE_29 phytoene synthetase [Lipid metabolism]LeptoII_scaffold_27_GENE_30 creatinase [General function prediction only]LeptoII_scaffold_27_GENE_31 chromosome partitioning ATPase [Cell divison and chromosome partitioning]LeptoII_scaffold_27_GENE_32 hypo unique hypo uniqueLeptoII_scaffold_27_GENE_33 muramoyltetrapeptide carboxypeptidase inv. in antibiotic resist. [Defense mechanisms]LeptoII_scaffold_27_GENE_34 hypo unique hypo unique - abundant extracellularLeptoII_scaffold_27_GENE_35 hypo unique hypo uniqueLeptoII_scaffold_27_GENE_36 27-36=tRNA Glu=27-37 hypo unique hypo uniqueLeptoII_scaffold_27_GENE_37 phosphoglycolate phosphatase [General function prediction only]LeptoII_scaffold_27_GENE_38 hypo unique hypo unique, possible starvation-inducible outer membrane lipoproteinLeptoII_scaffold_27_GENE_39 hypo unique hypo unique - possible phage-shock operon proteinLeptoII_scaffold_27_GENE_40 Phage shock protein PspA phage shock protein [Transcription]LeptoII_scaffold_27_GENE_41 hypo unique hypo unique - possible phage-shock operon proteinLeptoII_scaffold_27_GENE_42 c hypo c hypo - possible phage-shock operon proteinLeptoII_scaffold_27_GENE_43 27-43=tRNA Leu=27-44 hypo unique hypo unique- possible phage-shock operon proteinLeptoII_scaffold_27_GENE_44 hypo unique hypo uniqueLeptoII_scaffold_27_GENE_45 recombinase, fragment DNA recombinase, shufflon specific (fragment, part domain) [DNA replication, recombination, and repair]

LeptoII_scaffold_27_GENE_46 hypo unique hypo uniqueLeptoII_scaffold_27_GENE_47 methyltransferase/helicase [DNA replication, recombination, and repair]LeptoII_scaffold_27_GENE_48 c hypo c hypoLeptoII_scaffold_27_GENE_49 c hypo c hypoLeptoII_scaffold_27_GENE_50 hypo unique hypo uniqueLeptoII_scaffold_27_GENE_51 hypo unique hypo uniqueLeptoII_scaffold_27_GENE_52 hypo unique hypo uniqueLeptoII_scaffold_27_GENE_53 hypo unique hypo uniqueLeptoII_scaffold_27_GENE_54 hypo unique hypo uniqueLeptoII_scaffold_539_GENE_2 c hypo c hypoLeptoII_scaffold_539_GENE_3 DNA primase [DNA replication, recombination, and repair]LeptoII_scaffold_539_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_539_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_539_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_539_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_539_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_539_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_524_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_524_GENE_7 integrase fragment integrase fragment, INT 22C [DNA replication, recombination, and repair]LeptoII_scaffold_524_GENE_6 T (single) transposase transposaseLeptoII_scaffold_524_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_524_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_524_GENE_3 T (single) transposase transposaseLeptoII_scaffold_524_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_524_GENE_1 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]

LeptoII-10LeptoII_scaffold_120_GENE_1 T5, T6 transposase transposaseLeptoII_scaffold_120_GENE_2 glutamine amidotransferase [Amino acid transport and metabolism]LeptoII_scaffold_120_GENE_3 heavy metal efflux pump CzcA [Defense mechanisms]LeptoII_scaffold_120_GENE_4 efflux protein, CzcB [Defense mechanisms]LeptoII_scaffold_120_GENE_5 tyrosyl tRNA synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_120_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_120_GENE_7 nucleoside diphosphate kinase [Nucleotide transport and metabolism]LeptoII_scaffold_120_GENE_8 c hypo c hypoLeptoII_scaffold_120_GENE_9 dTDP-glucose 4,6-dehydratase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_120_GENE_10 sugar fermentation stimulation protein [General function prediction only]LeptoII_scaffold_120_GENE_11 UDP-glucose 6-dehydrogenase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_120_GENE_12 glycine oxidase (sarcosine oxidase) [Amino acid transport and metabolism]LeptoII_scaffold_120_GENE_13 c hypo c hypoLeptoII_scaffold_25_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_25_GENE_2 cytochrome c oxidase, fixO subunit [Energy production and conversion]LeptoII_scaffold_25_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_25_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_25_GENE_5 hypo unique hypo unique similar to cytochrome c (63% to L3:225-15)LeptoII_scaffold_25_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_25_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_25_GENE_8 cytochrome c oxidase, cbb3 type, subunit I [Energy production and conversion]LeptoII_scaffold_25_GENE_9 serine/threonine kinase [General function prediction only]LeptoII_scaffold_25_GENE_10 cytochrome c oxidase, cbb3 type, subunit I [Energy production and conversion]LeptoII_scaffold_25_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_25_GENE_12 Fe-S binding protein, FixG [Energy production and conversion]LeptoII_scaffold_25_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_25_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_25_GENE_15 c hypo c hypoLeptoII_scaffold_25_GENE_16 ADP-ribose pyrophosphatase [Nucleotide transport and metabolism]LeptoII_scaffold_25_GENE_17 polyferredoxin [Energy production and conversion]LeptoII_scaffold_25_GENE_18 sensory box protein/sigma 54 dependent DNA-binding… [Transcription]LeptoII_scaffold_25_GENE_19 anthranilate synthase component I [Amino acid transport and metabolism]LeptoII_scaffold_25_GENE_20 anthranilate synthase component II [Amino acid transport and metabolism]LeptoII_scaffold_25_GENE_21 anthranilate phosphoribosyltransferase [Amino acid transport and metabolism]LeptoII_scaffold_25_GENE_22 indole-3-glycerol phosphate synthase [Amino acid transport and metabolism]LeptoII_scaffold_25_GENE_23 N-(5' phosphoribosyl)anthranilate isomerase [Amino acid transport and metabolism]LeptoII_scaffold_25_GENE_24 tryptophan synthase, beta subunit [Amino acid transport and metabolism]LeptoII_scaffold_25_GENE_25 tryptophan synthase alpha chain [Amino acid transport and metabolism]LeptoII_scaffold_25_GENE_26 acetyl-CoA carboxylase [Lipid metabolism]LeptoII_scaffold_25_GENE_27 folylpolyglutamate synthase [Coenzyme metabolism]LeptoII_scaffold_25_GENE_28 organic solvent tolerance protein [Defense mechanisms]LeptoII_scaffold_25_GENE_29 c hypo c hypo (faint similarity to carboxypeptidase D)LeptoII_scaffold_25_GENE_30 ATP-NAD kinase [Carbohyhrate transport and metabolism]LeptoII_scaffold_25_GENE_31 glutamate synthase [Amino acid transport and metabolism]

LeptoII_scaffold_25_GENE_32 cytochrome b6 complex Rieske Fe-S protein (complex III) [Energy production and conversion]LeptoII_scaffold_25_GENE_33 cytochrome b subunit of bc complex (complex III) [Energy production and conversion]LeptoII_scaffold_25_GENE_34 c hypo (sim. to menaquinol-cytochrome c reductase, c sub. complex III)LeptoII_scaffold_25_GENE_35 hypo unique hypo uniqueLeptoII_scaffold_25_GENE_36 c hypo c hypo (putative cytochrome c oxidase subunit)LeptoII_scaffold_25_GENE_37 ABC transporter, ATP-binding protein involved in multidrug transp[Defense mechanisms]LeptoII_scaffold_25_GENE_38 ABC transporter, permease protein involved in multidrug transport [Defense mechanisms]LeptoII_scaffold_25_GENE_39 c hypo c hypoLeptoII_scaffold_25_GENE_40 signal peptide peptidase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_25_GENE_41 hypo unique hypo uniqueLeptoII_scaffold_25_GENE_42 glycerate kinase [Carbohyhrate transport and metabolism]LeptoII_scaffold_25_GENE_43 hypo unique hypo uniqueLeptoII_scaffold_25_GENE_44 ATP synthase/transcription termination [General function prediction only]LeptoII_scaffold_25_GENE_45 hypo unique hypo uniqueLeptoII_scaffold_25_GENE_46 hypo unique hypo uniqueLeptoII_scaffold_25_GENE_47 hypo unique hypo uniqueLeptoII_scaffold_25_GENE_48 c hypo c hypoLeptoII_scaffold_25_GENE_49 multidrug efflux transporter [Defense mechanisms]LeptoII_scaffold_25_GENE_50 inosine-5-monphosphate dehydrogenase [Nucleotide transport and metabolism]LeptoII_scaffold_25_GENE_51 ATP/GTP hydrolase [General function prediction only]LeptoII_scaffold_25_GENE_52 HIT family hydrolase [Nucleotide transport and metabolism]LeptoII_scaffold_25_GENE_53 hypo unique hypo uniqueLeptoII_scaffold_25_GENE_54 uracil phosphoribosyltransferase [Nucleotide transport and metabolism]LeptoII_scaffold_25_GENE_55 aspartate carbamoyltransferase [Nucleotide transport and metabolism]LeptoII_scaffold_25_GENE_56 dihydroorotase [Nucleotide transport and metabolism]LeptoII_scaffold_25_GENE_57 carbamoyl phosphate synthetase, small subunit [Amino acid transport and metabolism]LeptoII_scaffold_25_GENE_58 pyruvate formate-lyase 1 activating enzyme [Energy production and conversion]LeptoII_scaffold_25_GENE_59 carbamoyl phosphate synthetase, large subunit [Amino acid transport and metabolism]LeptoII_scaffold_25_GENE_60 transcription elongation factor [Transcription]LeptoII_scaffold_25_GENE_61 hypo unique hypo uniqueLeptoII_scaffold_1108_GENE_3 hypo unique hypo unique, possible transglycosylase

LeptoII-11LeptoII_scaffold_581_GENE_9 T (single in LII, also in LeptoIII) transposase transposaseLeptoII_scaffold_581_GENE_8 T (single in LII, also in LeptoIII) transposase transposaseLeptoII_scaffold_581_GENE_7 T10 transposase transposaseLeptoII_scaffold_581_GENE_6 T5 transposase transposaseLeptoII_scaffold_581_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_581_GENE_4 T10 transposase transposaseLeptoII_scaffold_581_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_581_GENE_2 carbonic anhydrase [General function prediction only]LeptoII_scaffold_62_GENE_1 hypo unique hypo unique - suspect transport-related?LeptoII_scaffold_62_GENE_2 ABC transporter permease protein [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_62_GENE_3 ABC transporter ATP-binding protein [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_62_GENE_4 ABC transporter periplasmic substrate binding protein [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_62_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_62_GENE_6 oxidoreductase/K+-channel protein? [Inorganic ion transport and metabolism]LeptoII_scaffold_62_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_62_GENE_8 c hypo c hypoLeptoII_scaffold_62_GENE_9 c hypo c hypoLeptoII_scaffold_62_GENE_10 Thiol disulfide isomerase, thioredoxin exAb.AbMem [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_62_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_62_GENE_12 adenylate cyclase [Signal transduction mechanisms]LeptoII_scaffold_62_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_62_GENE_14 hypo unique hypo unique, possible thioredoxinLeptoII_scaffold_62_GENE_15 phosphoribosylaminoimidazole carboxylase, ATPase subunit [Nucleotide transport and metabolism]LeptoII_scaffold_62_GENE_16 phosphoribosylaminoimidazole carboxylase [Nucleotide transport and metabolism]LeptoII_scaffold_62_GENE_17 NADP-reducing hydrogenase subunit C [Energy production and conversion]LeptoII_scaffold_62_GENE_18 hypo unique hypo unique (ferredoxin-like)LeptoII_scaffold_62_GENE_19 hypo unique hypo unique (contains TPR domain)LeptoII_scaffold_62_GENE_20 transglycosylase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_62_GENE_21 transcriptional regulator [Transcription]LeptoII_scaffold_62_GENE_22 hypo unique hypo uniqueLeptoII_scaffold_62_GENE_23 transposase transposaseLeptoII_scaffold_62_GENE_24 glycogen synthase [Carbohyhrate transport and metabolism]LeptoII_scaffold_62_GENE_25 c hypo c hypo, possible acyl desaturaseLeptoII_scaffold_62_GENE_26 hypo unique hypo uniqueLeptoII_scaffold_62_GENE_27 ferredoxin-nitrite reductase / sulfite reductase (cysI domain) [Inorganic ion transport and metabolism]LeptoII_scaffold_67_GENE_1 hypo unique hypo unique (identical in C-drift library)LeptoII_scaffold_67_GENE_2 proteophosphoglycan [Cell envelope biogenesis, outer membrane]

LeptoII_scaffold_67_GENE_3 integrase XerDC integrase [DNA replication, recombination, and repair]LeptoII_scaffold_67_GENE_4 oxygen independen coproporphyrinogen III oxidase [Coenzyme metabolism]LeptoII_scaffold_67_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_67_GENE_6 MoxR-like ATPase [General function prediction only]LeptoII_scaffold_67_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_67_GENE_8 possible DNA-dependent RNA polymeraseLeptoII_scaffold_67_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_67_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_67_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_67_GENE_12 pilus biogenesis traC pilus biogenesis protein [Intracellular trafficking and secretion]LeptoII_scaffold_67_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_67_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_67_GENE_15 hypo unique hypo unique found in alternative reading frameLeptoII_scaffold_67_GENE_16 3-hydroxyacid dehydrogenase [Lipid metabolism]LeptoII_scaffold_67_GENE_17 ABC transporter ATP-binding protein for antimicrobial peptides [Defense mechanisms]LeptoII_scaffold_67_GENE_18 ABC transporter permease protein for antimicrobial peptides [Defense mechanisms]LeptoII_scaffold_67_GENE_19 c hypo c hypoLeptoII_scaffold_67_GENE_20 c hypo c hypoLeptoII_scaffold_67_GENE_21 hypo unique hypo uniqueLeptoII_scaffold_67_GENE_22 transcriptional regulator [Transcription]LeptoII_scaffold_67_GENE_23 hypo unique hypo unique, possible methyl-accepting chemotaxis proteinLeptoII_scaffold_67_GENE_24 prolipoprotein diacylglycerol transferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_67_GENE_25 c hypo c hypo, possible dnaK deletion suppressor proteinLeptoII_scaffold_67_GENE_26 endonuclease III [DNA replication, recombination, and repair]LeptoII_scaffold_67_GENE_27 NADH dehydrogenase subunit F [Energy production and conversion]

LeptoII-12LeptoII_scaffold_22_GENE_1 T5 transposase transposaseLeptoII_scaffold_22_GENE_2 histone deacetylase [Transcription]LeptoII_scaffold_22_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_22_GENE_4 fructose bisphophatase [Carbohyhrate transport and metabolism]LeptoII_scaffold_22_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_22_GENE_6 aldehyde dehydrogenase [Energy production and conversion]LeptoII_scaffold_22_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_22_GENE_8 thymidylate synthase [Nucleotide transport and metabolism]LeptoII_scaffold_22_GENE_9 phosphate transporter transcriptional regulator [Inorganic ion transport and metabolism]LeptoII_scaffold_22_GENE_10 phosphate ABC transporter, ATP-binding domain [Inorganic ion transport and metabolism]LeptoII_scaffold_22_GENE_11 phosphate ABC transporter, permease protein [Inorganic ion transport and metabolism]LeptoII_scaffold_22_GENE_12 phosphate ABC transporter, permease protein [Inorganic ion transport and metabolism]LeptoII_scaffold_22_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_22_GENE_14 phosphate binding periplasmic protein, ABC transporter Ab Ex. Fn[Inorganic ion transport and metabolism]LeptoII_scaffold_22_GENE_15 hypo unique hypo uniqueLeptoII_scaffold_22_GENE_16 hypo unique hypo uniqueLeptoII_scaffold_22_GENE_17 DNA-binding response regulator PhoB [Signal transduction mechanisms]LeptoII_scaffold_22_GENE_18 hypo unique hypo uniqueLeptoII_scaffold_22_GENE_19 c hypo c hypoLeptoII_scaffold_22_GENE_20 adenylosuccinate synthetase [Nucleotide transport and metabolism]LeptoII_scaffold_22_GENE_21 c hypo c hypoLeptoII_scaffold_22_GENE_22 NADH oxidase (noxC)/nitroreductase [Energy production and conversion]LeptoII_scaffold_22_GENE_23 ubiquinone biosynthesis protein [Coenzyme metabolism]LeptoII_scaffold_22_GENE_24 DNA repair protein RadC [DNA replication, recombination, and repair]LeptoII_scaffold_22_GENE_25 hypo unique hypo uniqueLeptoII_scaffold_22_GENE_26 hypo unique hypo uniqueLeptoII_scaffold_22_GENE_27 c hypo c hypoLeptoII_scaffold_22_GENE_28 hypo unique hypo uniqueLeptoII_scaffold_22_GENE_29 22-29=tRNA Gln=22-30 membrane carboxypeptidase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_22_GENE_30 cellulase [Carbohyhrate transport and metabolism]LeptoII_scaffold_22_GENE_31 cyclic di-GMP binding protein (cellulose synthase subunit) [Carbohyhrate transport and metabolism]LeptoII_scaffold_22_GENE_32 glycosyltransferase [Carbohyhrate transport and metabolism]LeptoII_scaffold_22_GENE_33 cellulose synthase, subunit c: cleaves diGMP synthase… [Carbohyhrate transport and metabolism]LeptoII_scaffold_22_GENE_34 major facilitator family permease [Carbohyhrate transport and metabolism]LeptoII_scaffold_22_GENE_35 c hypo c hypo (faint similarity to nitrogen regulatory protein PII)LeptoII_scaffold_22_GENE_36 c hypo c hypoLeptoII_scaffold_22_GENE_37 NADH dehydrogenase, subunit 4 [Energy production and conversion]LeptoII_scaffold_22_GENE_38 NADH dehydrogenase, subunit 5 [Energy production and conversion]LeptoII_scaffold_22_GENE_39 transcriptional regulator (nifA family) [Transcription]LeptoII_scaffold_22_GENE_40 hypo unique hypo uniqueLeptoII_scaffold_22_GENE_41 flagellar motor switch protein FliM [Cell motility and secretion / Intracellular trafficking and secretLeptoII_scaffold_22_GENE_42 efflux transporter [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_22_GENE_43 ABC transporter, permease protein for antimicrobial peptides [Defense mechanisms]LeptoII_scaffold_22_GENE_44 ABC transporter, ATP binding protein for antimicrobial peptides [Defense mechanisms]

LeptoII_scaffold_22_GENE_45 pyrophosphatase [General function prediction only]LeptoII_scaffold_22_GENE_46a hypo unique hypo unique found overlapping 22-46LeptoII_scaffold_22_GENE_46b hypo unique hypo uniqueLeptoII_scaffold_22_GENE_47 hypo unique hypo uniqueLeptoII_scaffold_22_GENE_48 hypo unique hypo uniqueLeptoII_scaffold_22_GENE_49 T6 transposase transposase

LeptoII-13LeptoII_scaffold_26_GENE_1 c hypo c hypoLeptoII_scaffold_26_GENE_2 c hypo c hypoLeptoII_scaffold_26_GENE_3 CRISPR-associated protein Cas1 [General function prediction only]LeptoII_scaffold_26_GENE_4 c hypo c hypoLeptoII_scaffold_26_GENE_5 c hypo c hypoLeptoII_scaffold_26_GENE_6 c hypo c hypoLeptoII_scaffold_26_GENE_7 c hypo c hypoLeptoII_scaffold_26_GENE_8 c hypo c hypoLeptoII_scaffold_26_GENE_9 RNA helicase [DNA replication, recombination, and repair]LeptoII_scaffold_26_GENE_10 T3 transposase transposaseLeptoII_scaffold_26_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_26_GENE_12 T (single) transposase transposaseLeptoII_scaffold_26_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_26_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_26_GENE_15 DNA methyltransferase/helicase [DNA replication, recombination, and repair]LeptoII_scaffold_26_GENE_16 c hypo c hypoLeptoII_scaffold_26_GENE_17 c hypo c hypoLeptoII_scaffold_26_GENE_18 hypo unique hypo uniqueLeptoII_scaffold_26_GENE_19 c hypo c hypoLeptoII_scaffold_26_GENE_20 possibly virulence associated c hypo c hypo, possibly virulence associatedLeptoII_scaffold_26_GENE_21 phage binding phage DNA binding protein [Transcription]LeptoII_scaffold_26_GENE_22 hypo unique hypo uniqueLeptoII_scaffold_26_GENE_23 integrase - phage/plasmid related integrase INT P4 [DNA replication, recombination, and repair]LeptoII_scaffold_26_GENE_24 srA-binding protein/tmRNA-binding protein [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_26_GENE_25 leucyl aminopeptidase [Amino acid transport and metabolism]LeptoII_scaffold_26_GENE_26 ExsB protein: succinoglycan synthesis/transcription/ATPase [General function prediction only]LeptoII_scaffold_26_GENE_27 radical SAM enzyme/Fe-S redox protein [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_26_GENE_28 hypo unique hypo uniqueLeptoII_scaffold_26_GENE_29 DNA gyrase [DNA replication, recombination, and repair]LeptoII_scaffold_26_GENE_30 DNA gyrase, subunit B [DNA replication, recombination, and repair]LeptoII_scaffold_26_GENE_31 DNA polymerase III [DNA replication, recombination, and repair]LeptoII_scaffold_26_GENE_32 chromosomal replication initiator protein DnaA [DNA replication, recombination, and repair]LeptoII_scaffold_26_GENE_33 acetolactate synthase [Amino acid transport and metabolism]LeptoII_scaffold_26_GENE_34 acetolactate synthase [Amino acid transport and metabolism]LeptoII_scaffold_26_GENE_35 ketol-acid reductoisomerase [Amino acid transport and metabolism]LeptoII_scaffold_26_GENE_36 phosphatidylserine decarboxylase [Lipid metabolism]LeptoII_scaffold_26_GENE_37 CDP-diacylglycerol-serine O-phosphatidyltransferase [Lipid metabolism]LeptoII_scaffold_26_GENE_38 2-isopropylmalate synthase [Amino acid transport and metabolism]LeptoII_scaffold_26_GENE_39 isocitrate dehydrogenase [Amino acid transport and metabolism]LeptoII_scaffold_26_GENE_40 aspartate semialdehyde dehydrogeanse [Amino acid transport and metabolism]LeptoII_scaffold_26_GENE_41 quinolinate synthetase complex [Coenzyme metabolism]LeptoII_scaffold_26_GENE_42 c hypo c hypoLeptoII_scaffold_26_GENE_43 hypo unique hypo unique found in alternative reading frameLeptoII_scaffold_26_GENE_44 ferridoxin oxidoreductase [Energy production and conversion]LeptoII_scaffold_26_GENE_45 glutathione transferase [Amino acid transport and metabolism]LeptoII_scaffold_26_GENE_46 hypo unique hypo uniqueLeptoII_scaffold_26_GENE_47 hypo unique hypo uniqueLeptoII_scaffold_26_GENE_48 c hypo c hypo

LeptoII-14LeptoII_scaffold_42_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_2 hypo unique hypo unique - very abundantLeptoII_scaffold_42_GENE_3 hemolysin [General function prediction only]LeptoII_scaffold_42_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_5a hypo unique hypo unique - possibly related to chaperone activityLeptoII_scaffold_42_GENE_5b hypo unique hypo unique found overlapping 42-5LeptoII_scaffold_42_GENE_6 c hypo c hypoLeptoII_scaffold_42_GENE_7 cysteine desulfurase [Amino acid transport and metabolism]LeptoII_scaffold_42_GENE_8 nifU homolog involved in maturation of Fe-S clusters [Energy production and conversion]LeptoII_scaffold_42_GENE_9 HesB/iron-sulfur cluster assembly accessory protein [Energy production and conversion]LeptoII_scaffold_42_GENE_10 chaperone protein HscB [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_42_GENE_11 chaperone protein dnaK [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_42_GENE_12 chaperone protein HscA [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_42_GENE_13 ferridoxin [Energy production and conversion]

LeptoII_scaffold_42_GENE_14 c hypo c hypoLeptoII_scaffold_42_GENE_15 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_16 ATPase involved in chromosome partitioning [Cell divison and chromosome partitioning]LeptoII_scaffold_42_GENE_17 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_18 tRNA pseudouridine synthase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_42_GENE_19 c hypo c hypoLeptoII_scaffold_42_GENE_20 glycerol-3-phosphate dehydrogenase [Energy production and conversion]LeptoII_scaffold_42_GENE_21 phosphoribosyltransferase [General function prediction only]LeptoII_scaffold_42_GENE_22 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_23 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_42_GENE_24 phospholipid binding protein [General function prediction only]LeptoII_scaffold_42_GENE_25 seryl tRNA synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_42_GENE_26 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_27 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_28 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_29 GTPases [General function prediction only]LeptoII_scaffold_42_GENE_30 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_31 c hypo c hypoLeptoII_scaffold_42_GENE_32 hypo unique hypo unique - suspect related to peptidase activityLeptoII_scaffold_42_GENE_33 peptidase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_42_GENE_34 zinc-dependent peptidase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_42_GENE_35 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_36 Na+/H+ antiporter [Inorganic ion transport and metabolism]LeptoII_scaffold_42_GENE_37 metabolite transport protein [Carbohyhrate transport and metabolism]LeptoII_scaffold_42_GENE_38 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_39 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_40 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_41 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_42 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_43 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_44 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_45 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_46 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_47 hypo unique hypo uniqueLeptoII_scaffold_42_GENE_48 T6 transposase transposaseLeptoII_scaffold_42_GENE_49 hypo unique hypo unique

LeptoII-15LeptoII_scaffold_43_GENE_1 acriflavine resistance protein/outer membrane efflux protein [Defense mechanisms]LeptoII_scaffold_43_GENE_2 cation efflux transporter involved in multidrug efflux [Defense mechanisms]LeptoII_scaffold_43_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_43_GENE_4 Xaa-proline aminopeptidase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_43_GENE_5 O-methyltransferase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_43_GENE_6 assimilatory nitrate reductase subunit [Inorganic ion transport and metabolism / General function preLeptoII_scaffold_43_GENE_7 sugar metabolism [Carbohyhrate transport and metabolism]LeptoII_scaffold_43_GENE_8 glucose-t-phosphate adenyltransferase [Carbohyhrate transport and metabolism]LeptoII_scaffold_43_GENE_9 amylopullulanase [Carbohyhrate transport and metabolism]LeptoII_scaffold_43_GENE_10 alpha-amylase [Carbohyhrate transport and metabolism]LeptoII_scaffold_43_GENE_11 galactose-1-phosphate uridylyltransferase [Carbohyhrate transport and metabolism]LeptoII_scaffold_43_GENE_12a hypo unique hypo unique found overlapping 43-12LeptoII_scaffold_43_GENE_12b hypo unique hypo unique, possible fructose bisphosphate aldolaseLeptoII_scaffold_43_GENE_13 c hypo c hypoLeptoII_scaffold_43_GENE_14 efflux transporter involved in multidrug efflux [Defense mechanisms]LeptoII_scaffold_43_GENE_15 cation efflux transport involved in multidrug efflux [Defense mechanisms]LeptoII_scaffold_43_GENE_16 glycine cleavage system; aminomethyltransferase [General function prediction only]LeptoII_scaffold_43_GENE_17 acetoacetate metabolism regulatory protein atoC [Signal transduction mechanisms]LeptoII_scaffold_43_GENE_18 efflux transporter involved in multidrug efflux [Defense mechanisms]LeptoII_scaffold_43_GENE_19 efflux protein involved in multidrug efflux [Defense mechanisms]LeptoII_scaffold_43_GENE_20 thioredoxin reductase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_43_GENE_21 hypo unique hypo uniqueLeptoII_scaffold_43_GENE_22 hypo unique hypo uniqueLeptoII_scaffold_43_GENE_23 thymidylate kinase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_43_GENE_24 carboxylesterase [General function prediction only]LeptoII_scaffold_43_GENE_25 hypo unique hypo uniqueLeptoII_scaffold_43_GENE_26 peptide deformylase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_43_GENE_27 methionyl tRNA formyltransferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_43_GENE_28 M48 peptidase/Zn+-dependent protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_43_GENE_29 ribulose phosphate 3-epimerase [Carbohyhrate transport and metabolism]LeptoII_scaffold_43_GENE_30 hypo unique hypo uniqueLeptoII_scaffold_43_GENE_31 actin-like ATPase [Cell divison and chromosome partitioning]LeptoII_scaffold_277_GENE_3 rod shape determining protein MreC [Cell divison and chromosome partitioning]

LeptoII_scaffold_277_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_277_GENE_5 cell division protein FtsI [Cell divison and chromosome partitioning]LeptoII_scaffold_277_GENE_6 rod shape determining protein RodA [Cell divison and chromosome partitioning]LeptoII_scaffold_277_GENE_7 ribonuclease G [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_277_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_277_GENE_9 7,8-dihydroneopterin aldolase [Coenzyme metabolism]LeptoII_scaffold_277_GENE_10 hypo unique hypo unique

LeptoII-16LeptoII_scaffold_44_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_44_GENE_2 phosphatidylglycerophosphatase A [Lipid metabolism]LeptoII_scaffold_44_GENE_3 RecA [DNA replication, recombination, and repair]LeptoII_scaffold_44_GENE_4 alanyl tRNA synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_44_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_44_GENE_6 DNA integration recombination protein [DNA replication, recombination, and repair]LeptoII_scaffold_44_GENE_7 4-amino-4-deoxychorismate lyase [Coenzyme metabolism]LeptoII_scaffold_44_GENE_8 valyl tRNA synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_44_GENE_9 nicotinate-nucleotide pyrophosphorylase [Coenzyme metabolism]LeptoII_scaffold_44_GENE_10 biotin operon repressor BirA [Coenzyme metabolism]LeptoII_scaffold_44_GENE_11 c hypo c hypoLeptoII_scaffold_44_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_44_GENE_13 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_44_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_44_GENE_15 multi-drug resistance efflux pump [Defense mechanisms]LeptoII_scaffold_44_GENE_16 outer membrane protein TolC [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_44_GENE_17 malate dehydrogenase [Energy production and conversion]LeptoII_scaffold_44_GENE_18 hypo unique hypo uniqueLeptoII_scaffold_44_GENE_19 hypo unique hypo uniqueLeptoII_scaffold_44_GENE_20 ABC transporter [General function prediction only]LeptoII_scaffold_44_GENE_21 RNA polymerase sigma-54 factor [Transcription]LeptoII_scaffold_44_GENE_22 ribosomal protein S30 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_44_GENE_23 c hypo c hypo (contains ATP-binding domain)LeptoII_scaffold_44_GENE_24 hypo unique hypo unique - poss. rel. to phenylal.,, tyros., and trypt. biosyn.LeptoII_scaffold_44_GENE_25 chorismate synthase [Amino acid transport and metabolism]LeptoII_scaffold_44_GENE_26 shikimate kinase [Amino acid transport and metabolism]LeptoII_scaffold_44_GENE_27 3-dehydroquinate synthetase [Amino acid transport and metabolism]LeptoII_scaffold_44_GENE_28 sigma factor regulatory protein [Signal transduction mechanisms]LeptoII_scaffold_44_GENE_29 hypo unique hypo uniqueLeptoII_scaffold_44_GENE_30 c hypo c hypoLeptoII_scaffold_44_GENE_31 acetyl transferase [General function prediction only]LeptoII_scaffold_44_GENE_32 GTP cyclohydrolase I [General function prediction only]LeptoII_scaffold_44_GENE_33 transposase transposaseLeptoII_scaffold_44_GENE_34 44-33=tRNA Val=44-34 4-hydroxybenzoyl-coA-thioesterase [General function prediction only]LeptoII_scaffold_44_GENE_35 T6 transposase transposase

LeptoII-17LeptoII_scaffold_45_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_45_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_45_GENE_3 oxidoreductase [Energy production and conversion]LeptoII_scaffold_45_GENE_4 3-methyladenine DNA glycosylase [DNA replication, recombination, and repair]LeptoII_scaffold_45_GENE_5 methylated DNA protein cystein methyltransferase [DNA replication, recombination, and repair]LeptoII_scaffold_45_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_45_GENE_7 c hypo c hypoLeptoII_scaffold_45_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_45_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_45_GENE_10 3-methyladenine DNA glycosylase [DNA replication, recombination, and repair]LeptoII_scaffold_45_GENE_11 c hypo c hypoLeptoII_scaffold_45_GENE_12 c hypo c hypoLeptoII_scaffold_45_GENE_13a c hypo c hypo found overlapping 45-13LeptoII_scaffold_45_GENE_13b thymidine phosphorylaseLeptoII_scaffold_45_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_45_GENE_15a c hypo c hypo found overlapping 45-15LeptoII_scaffold_45_GENE_15b c hypo c hypoLeptoII_scaffold_45_GENE_16 hypo unique hypo uniqueLeptoII_scaffold_45_GENE_17 DNA binding protein [General function prediction only]LeptoII_scaffold_45_GENE_18 formate hydrogenlyase subunit III [Energy production and conversion]LeptoII_scaffold_45_GENE_19 formate hydrogenlyase subunit IV [Energy production and conversion]LeptoII_scaffold_45_GENE_20 hydrogenase, membrane subunit [Energy production and conversion]LeptoII_scaffold_45_GENE_21 hydrogenase 4, membrane subunit [Energy production and conversion]LeptoII_scaffold_45_GENE_22 hydrogenase 3, subunit E / Ni,Fe, hydrogenase [Energy production and conversion]LeptoII_scaffold_45_GENE_23 hydrogenase 3, subunit G [Energy production and conversion]LeptoII_scaffold_45_GENE_24 alginate regulatory protein [Carbohyhrate transport and metabolism]

LeptoII_scaffold_45_GENE_25 transcriptional regulator [Transcription]LeptoII_scaffold_45_GENE_26 hypo unique hypo uniqueLeptoII_scaffold_45_GENE_27 hypo unique hypo uniqueLeptoII_scaffold_45_GENE_28 c hypo c hypoLeptoII_scaffold_45_GENE_29 hypo unique hypo uniqueLeptoII_scaffold_45_GENE_30 hypo unique hypo uniqueLeptoII_scaffold_45_GENE_31 c hypo c hypoLeptoII_scaffold_45_GENE_32 c hypo c hypoLeptoII_scaffold_45_GENE_33 c hypo c hypoLeptoII_scaffold_45_GENE_34 plasmid stabilization StbC plasmid stabilization protein, StbC [Cell divison and chromosome partitioning]LeptoII_scaffold_45_GENE_35 plasmid stabilization StbB plasmid stabilization protein, StbB [Cell divison and chromosome partitioning]LeptoII_scaffold_45_GENE_36 c hypo c hypoLeptoII_scaffold_45_GENE_37 T (single) transposase transposaseLeptoII_scaffold_45_GENE_38 T (single) transposase transposaseLeptoII_scaffold_45_GENE_39 hypo unique hypo uniqueLeptoII_scaffold_45_GENE_40 c hypo c hypoLeptoII_scaffold_45_GENE_41 response regulator (HD-GYP domain/GGDEF domain) [Signal transduction mechanisms]LeptoII_scaffold_45_GENE_42 hypo unique hypo uniqueLeptoII_scaffold_45_GENE_43 c hypo c hypoLeptoII_scaffold_45_GENE_44 hypo unique hypo uniqueLeptoII_scaffold_45_GENE_45 transcriptional regulator [Transcription]LeptoII_scaffold_45_GENE_46 c hypo c hypoLeptoII_scaffold_45_GENE_47 hypo unique hypo uniqueLeptoII_scaffold_45_GENE_48 T10 transposase transposase

LeptoII-18LeptoII_scaffold_297_GENE_8 high affinity Fe permease [Inorganic ion transport and metabolism]LeptoII_scaffold_297_GENE_7 c hypo c hypoLeptoII_scaffold_297_GENE_6 c hypo c hypo - kelch-like proteinLeptoII_scaffold_297_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_297_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_297_GENE_3 T5 transposase transposaseLeptoII_scaffold_46_GENE_2 arsenate reductase [Defense mechanisms]LeptoII_scaffold_46_GENE_3 arsenite efflux pump, ArsB [Defense mechanisms]LeptoII_scaffold_46_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_46_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_46_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_46_GENE_7 cation efflux protein for multidrug efflux [Defense mechanisms]LeptoII_scaffold_46_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_46_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_46_GENE_10 c hypo c hypoLeptoII_scaffold_46_GENE_11 glucose-6-phosphate isomerase [Carbohyhrate transport and metabolism]LeptoII_scaffold_46_GENE_12 LexA transcriptional repressor [Transcription]LeptoII_scaffold_46_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_46_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_46_GENE_15 DNA polymerase B2 [DNA replication, recombination, and repair]LeptoII_scaffold_46_GENE_16 cytochrome c (74% to 46-27) [Energy production and conversion]LeptoII_scaffold_46_GENE_17 soluble cytochrome cB/cytochrome c553 (71% to 46-26) [Energy production and conversion]LeptoII_scaffold_46_GENE_18 cellulose synthase, subunit A [Carbohyhrate transport and metabolism]LeptoII_scaffold_46_GENE_19 cellulose synthase, subunit B [Carbohyhrate transport and metabolism]LeptoII_scaffold_46_GENE_20 cellulose synthase, subunit C [Carbohyhrate transport and metabolism]LeptoII_scaffold_46_GENE_21 hypo unique hypo uniqueLeptoII_scaffold_46_GENE_22 hypo unique hypo uniqueLeptoII_scaffold_46_GENE_23 carotenoid isomerase/phytoene dehydrogenase [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_46_GENE_24 hypo unique hypo uniqueLeptoII_scaffold_46_GENE_25 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_46_GENE_26 cytochrome c (71% to 46-28) [Energy production and conversion]LeptoII_scaffold_46_GENE_27 cytochrome c (74% to 46-16, 48% to 46-28) [Energy production and conversion]LeptoII_scaffold_46_GENE_28 cytochrome c (71% to 46-26) [Energy production and conversion]LeptoII_scaffold_46_GENE_29 hypo unique hypo uniqueLeptoII_scaffold_46_GENE_30 hypo unique hypo unique

LeptoII-19LeptoII_scaffold_48_GENE_1 histone-like; abund Ext, Mem fractions [DNA replication, recombination, and repair]LeptoII_scaffold_48_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_48_GENE_3 Clp protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_48_GENE_4 transcriptional regulator [Transcription]LeptoII_scaffold_48_GENE_5 DnaJ protein [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_48_GENE_6 L-aspartate oxidase [Coenzyme metabolism]LeptoII_scaffold_48_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_48_GENE_8 glutamyl tRNA synthetase [Translation, ribosomal structure and biogenesis]

LeptoII_scaffold_48_GENE_9 c hypo c hypoLeptoII_scaffold_48_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_48_GENE_11 ferrodoxin oxidoreductase [Energy production and conversion]LeptoII_scaffold_48_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_48_GENE_13 pyruvate ferredoxin oxidoreductase [Energy production and conversion]LeptoII_scaffold_48_GENE_14 pyruvate:ferredoxin oxidoreductase [Energy production and conversion]LeptoII_scaffold_48_GENE_15 ferredoxin oxidoreductase [Energy production and conversion]LeptoII_scaffold_48_GENE_16 ferredoxin oxidoreductase [Energy production and conversion]LeptoII_scaffold_48_GENE_17a hypo unique hypo unique found in intergenic regionLeptoII_scaffold_48_GENE_17b hypo unique hypo uniqueLeptoII_scaffold_48_GENE_18 ferredoxin oxidoreductase [Energy production and conversion]LeptoII_scaffold_48_GENE_19 pyruvate:ferredoxin oxidoreductase [Energy production and conversion]LeptoII_scaffold_48_GENE_20 ferredoxin oxidoreductase [Energy production and conversion]LeptoII_scaffold_48_GENE_21 ferredoxin oxidoreductase [Energy production and conversion]LeptoII_scaffold_48_GENE_22 hypo unique hypo uniqueLeptoII_scaffold_48_GENE_23 chaperone DnaJ [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_48_GENE_24 hypo unique hypo uniqueLeptoII_scaffold_48_GENE_25 hypo unique hypo uniqueLeptoII_scaffold_48_GENE_26 glutamate-1-semialdehyde aminotransferase [Coenzyme metabolism]LeptoII_scaffold_48_GENE_27 phosphoheptose isomerase [Carbohyhrate transport and metabolism]LeptoII_scaffold_48_GENE_28 ADP-heptose synthase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_48_GENE_29 transcription-repair coupling factor [DNA replication, recombination, and repair]LeptoII_scaffold_48_GENE_30 peptidyl-prolyl cis-strans isomerase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_48_GENE_31 parvulin-like peptidyl-prolyl isomerase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_48_GENE_32 peptidyl-prolyl cis-strans isomerase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_48_GENE_33 GTP-binding protein [General function prediction only]LeptoII_scaffold_48_GENE_34 c hypo c hypoLeptoII_scaffold_48_GENE_35 mannose-1-phosphate guanylyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_48_GENE_36 c hypo c hypoLeptoII_scaffold_48_GENE_37 c hypo c hypoLeptoII_scaffold_48_GENE_38 hypo unique hypo uniqueLeptoII_scaffold_48_GENE_39 hypo unique hypo unique

LeptoII-20LeptoII_scaffold_137_GENE_8 DNA-directed RNA polymerase, beta' subunit [Transcription]LeptoII_scaffold_137_GENE_7 DNA-directed RNA polymerase, beta subunit [Transcription]LeptoII_scaffold_137_GENE_6 ribosomal protein L7/L12 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_137_GENE_5 ribosomal protein L10 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_137_GENE_4 ribosomal protein L1 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_137_GENE_3 50S ribosomal protein L11 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_137_GENE_2 137-1=tRNA Trp=137-2 transcription antitermination protein, NusG [Transcription]LeptoII_scaffold_137_GENE_1 GTPase elongation factor Tu [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_271_GENE_1 GTPase elongation factor Tu [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_271_GENE_2 271-1/2=tRNA Thr,Gly,Thr hypo unique hypo uniqueLeptoII_scaffold_271_GENE_3 flavoprotein oxidoreductase [Energy production and conversion]LeptoII_scaffold_271_GENE_4 271-4=tRNA Leu =271-5 hypo unique hypo uniqueLeptoII_scaffold_271_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_271_GENE_6 tRNA modifying enzyme/2-methylthioadenine synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_271_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_271_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_271_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_271_GENE_10 rare lipoprotein A [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_271_GENE_11 c hypo c hypoLeptoII_scaffold_53_GENE_1 ribosomal protein S18 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_53_GENE_2 single-strand DNA binding protein [DNA replication, recombination, and repair]LeptoII_scaffold_53_GENE_3 hypo unique hypo unique, possible ribosomal protein S6LeptoII_scaffold_53_GENE_4 GTP-binding protein [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_53_GENE_5 peptidyl tRNA hydrolase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_53_GENE_6 ribosomal protein L25 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_53_GENE_7 53-7=tRNA Gln=53-8 ribose-phosphate pyrophosphokinase [Nucleotide transport and metabolism]LeptoII_scaffold_53_GENE_8 4-diphosphocytidyl-2c-methyl-D-erythritol kinase [Lipid metabolism]LeptoII_scaffold_53_GENE_9 Fe-S oxidoreductase [Energy production and conversion]LeptoII_scaffold_53_GENE_10 CDP-alcohol phosphatidyl transferase [Lipid metabolism]LeptoII_scaffold_53_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_53_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_53_GENE_13 Clp protease ATP-binding subunit ClpX [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_53_GENE_14 protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_53_GENE_15 hypo unique hypo unique, possible peptidyl-prolyl cis-trans isomeraseLeptoII_scaffold_53_GENE_16 FAD-binding monooxygenase [Coenzyme metabolism]LeptoII_scaffold_53_GENE_17 hypo unique hypo unique

LeptoII_scaffold_53_GENE_18 glucose 6-phosphate deydrogenase [Carbohyhrate transport and metabolism]LeptoII_scaffold_53_GENE_19 transaldolase [Carbohyhrate transport and metabolism]LeptoII_scaffold_53_GENE_20 transketolase [Carbohyhrate transport and metabolism]LeptoII_scaffold_53_GENE_21 glucose 6-phosphate deydrogenase [Carbohyhrate transport and metabolism]LeptoII_scaffold_53_GENE_22 glucokinase [Carbohyhrate transport and metabolism]LeptoII_scaffold_53_GENE_23 hypo unique hypo uniqueLeptoII_scaffold_53_GENE_24 hypo unique hypo uniqueLeptoII_scaffold_53_GENE_25 c hypo c hypoLeptoII_scaffold_53_GENE_26 hypo unique hypo unique, possible dextran sucraseLeptoII_scaffold_53_GENE_27 c hypo c hypo (contains HD domain)LeptoII_scaffold_53_GENE_28 hypo unique hypo uniqueLeptoII_scaffold_682_GENE_2 T5 transposase transposaseLeptoII_scaffold_682_GENE_3 transcriptional regulator/mercury resistance regulator [Transcription]LeptoII_scaffold_682_GENE_4 mercuric reductase [Defense mechanisms]LeptoII_scaffold_283_GENE_1 T5 transposase transposaseLeptoII_scaffold_283_GENE_2 heme d1 biosynthesis protein NirJ [Coenzyme metabolism]LeptoII_scaffold_283_GENE_3 quinone oxidoreductase [Coenzyme metabolism]LeptoII_scaffold_283_GENE_4 serine/threonine protein phosphatase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_283_GENE_5 protoporphyrinogen oxidase [Coenzyme metabolism]LeptoII_scaffold_283_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_283_GENE_7 c hypo c hypoLeptoII_scaffold_283_GENE_8 chloride channel protein [Inorganic ion transport and metabolism]

LeptoII-21LeptoII_scaffold_57_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_57_GENE_2 c hypo c hypoLeptoII_scaffold_57_GENE_3 chorismate mutase [Amino acid transport and metabolism]LeptoII_scaffold_57_GENE_4 DAHP synthase in aromatic amino acid biosynthesis… [Amino acid transport and metabolism]LeptoII_scaffold_57_GENE_5 prephenate dehydrogenase [Amino acid transport and metabolism]LeptoII_scaffold_57_GENE_6 5-enolpyruvoylshikimate-3-phosphate synthase [Amino acid transport and metabolism]LeptoII_scaffold_57_GENE_7 cytidylate kinase [Nucleotide transport and metabolism]LeptoII_scaffold_57_GENE_8 acyltransferase [Lipid metabolism]LeptoII_scaffold_57_GENE_9 sodium/sulfate transporter [Inorganic ion transport and metabolism]LeptoII_scaffold_57_GENE_10 5-formyltetrahydrofolate cyclo-ligase [Coenzyme metabolism]LeptoII_scaffold_57_GENE_11 GTP cyclohydrolase I [Coenzyme metabolism]LeptoII_scaffold_57_GENE_12 methylenetetrahydrofolate reductase [Coenzyme metabolism]LeptoII_scaffold_57_GENE_13 methylenetetrahydrofolate reductase [Coenzyme metabolism]LeptoII_scaffold_57_GENE_14 keopantoate hydroxymethyltransferase [Coenzyme metabolism]LeptoII_scaffold_57_GENE_15 cation transport protein [Inorganic ion transport and metabolism]LeptoII_scaffold_57_GENE_16 exodeoxyribonuclease III [DNA replication, recombination, and repair]LeptoII_scaffold_57_GENE_17 c hypo cons hypo similar to acyl-[ACP] desaturasesLeptoII_scaffold_57_GENE_18 chemotaxis receptor (top match is L. ferrooxidans protein) [Cell motility and secretion]LeptoII_scaffold_57_GENE_19 glycolate oxidase [Energy production and conversion]LeptoII_scaffold_57_GENE_20 HD domain hydrolase [General function prediction only]LeptoII_scaffold_57_GENE_21 glutamate synthase (NADPH) large chain [Amino acid transport and metabolism]LeptoII_scaffold_57_GENE_22 c hypo c hypoLeptoII_scaffold_57_GENE_23 RNA polymerase [Transcription]LeptoII_scaffold_57_GENE_24 acylphosphatase [Lipid metabolism]LeptoII_scaffold_57_GENE_25 57-25=tRNA Pro=57-26 hypo unique hypo uniqueLeptoII_scaffold_57_GENE_26 fumarase [Energy production and conversion]

LeptoII-22LeptoII_scaffold_410_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_410_GENE_7 c hypo c hypoLeptoII_scaffold_410_GENE_6 410-5=tRNA Thr =410-6 chemotaxis protein CheV [Cell motility and secretion]LeptoII_scaffold_410_GENE_5 protein disulfide isomerase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_410_GENE_4 UDP-galactose-lipid carrier transferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_410_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_410_GENE_2 prepilin peptidase [Intracellular trafficking and secretion]LeptoII_scaffold_410_GENE_1 T5 transposase-like transposaseLeptoII_scaffold_134_GENE_11 hypo unique hypo unique, possiblel universal stress proteinLeptoII_scaffold_134_GENE_10 phosphate starvation inducible protein phoB [Signal transduction mechanisms]LeptoII_scaffold_134_GENE_9 metal dependant phosphohydrolase [General function prediction only]LeptoII_scaffold_134_GENE_8 c hypo c hypoLeptoII_scaffold_134_GENE_7 cell division protein FtsY [Intracellular trafficking and secretion]LeptoII_scaffold_134_GENE_6 shikimate 5-dehydrogenase [Amino acid transport and metabolism]LeptoII_scaffold_134_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_134_GENE_4 exonuclease ABC subunit C [DNA replication, recombination, and repair]LeptoII_scaffold_134_GENE_3 Clp protease ATP-binding subunit [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_66_GENE_1 thiamine biosynthesis protein ThiC (66-1, 134-2) [Coenzyme metabolism]LeptoII_scaffold_66_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_66_GENE_3 c hypo c hypo

LeptoII_scaffold_66_GENE_4 methionine synthase I, cobalamin binding domain [Amino acid transport and metabolism]LeptoII_scaffold_66_GENE_5 metal-dependant hydrolase PhnP [General function prediction only]LeptoII_scaffold_66_GENE_6 peptidyl-prolyl cis-trans isomerase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_66_GENE_7 GTP-binding protein [General function prediction only]LeptoII_scaffold_66_GENE_8 methyltransferase [General function prediction only]LeptoII_scaffold_66_GENE_9 c hypo c hypoLeptoII_scaffold_66_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_66_GENE_11 DNA repair protein, RecO [DNA replication, recombination, and repair]LeptoII_scaffold_66_GENE_12 GTP-binding protein, ERA [General function prediction only]LeptoII_scaffold_66_GENE_13 oxidoreductase/short chain dehydrogenase [General function prediction only]LeptoII_scaffold_66_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_66_GENE_15 hypo unique hypo uniqueLeptoII_scaffold_66_GENE_16 hypo unique hypo uniqueLeptoII_scaffold_66_GENE_17 DP-mannose pyrophosphorylase [Carbohyhrate transport and metabolism]LeptoII_scaffold_66_GENE_18 phosphomannomutase [Carbohyhrate transport and metabolism]LeptoII_scaffold_66_GENE_19 flavohemoglobin [Energy production and conversion]LeptoII_scaffold_66_GENE_20 hypo unique hypo uniqueLeptoII_scaffold_66_GENE_21 hypo unique hypo unique, possible Fe/Pb permease, cyt. c (unique to community) LeptoII_scaffold_66_GENE_22 naphthalene-1.2-dioxygenase reductase [Energy production and conversion]LeptoII_scaffold_66_GENE_23 c hypo c hypoLeptoII_scaffold_66_GENE_24 c hypo c hypoLeptoII_scaffold_66_GENE_25 hypo unique hypo uniqueLeptoII_scaffold_66_GENE_26 hypo unique hypo uniqueLeptoII_scaffold_66_GENE_27 long chain fatty-acid CoA ligase [Lipid metabolism]LeptoII_scaffold_66_GENE_28 cleavage and polyadenylation specificity factor [Translation, ribosomal structure and biogenesis]

LeptoII-23LeptoII_scaffold_214_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_214_GENE_1 T5 transposase transposaseLeptoII_scaffold_214_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_214_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_214_GENE_9 T5 transposase-like transposaseLeptoII_scaffold_214_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_214_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_214_GENE_6 integrase fragment integrase fragment /transposase (Tn domain) transposaseLeptoII_scaffold_214_GENE_5 T (single) transposase transposaseLeptoII_scaffold_214_GENE_4 DNA helicase [DNA replication, recombination, and repair]LeptoII_scaffold_214_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_214_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_80_GENE_3 T (single) transposase transposaseLeptoII_scaffold_80_GENE_4 T (single) transposase transposaseLeptoII_scaffold_80_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_80_GENE_6 T (single) transposase transposaseLeptoII_scaffold_80_GENE_7 large conductance mechanosensitive channel [General function prediction only]LeptoII_scaffold_80_GENE_8 Zn metalloprotease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_80_GENE_9 cobalamin biosynthesis protein [Coenzyme metabolism]LeptoII_scaffold_80_GENE_10 precorring-6y methylase [Coenzyme metabolism]LeptoII_scaffold_80_GENE_11 precorrin-6Y methylase [Coenzyme metabolism]LeptoII_scaffold_80_GENE_12 cobalamin biosynthesis protein CbiG [Coenzyme metabolism]LeptoII_scaffold_80_GENE_13 isopropylmalate dehydrogenase (cobalamin production) [Coenzyme metabolism]LeptoII_scaffold_80_GENE_14 cob(i)alamin adenosyltransferase [Coenzyme metabolism]LeptoII_scaffold_80_GENE_15 polypeptide deformylase (abundant in proteome) [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_80_GENE_16 orotidine-5'-phosphate decarboxylase [Nucleotide transport and metabolism]LeptoII_scaffold_80_GENE_17 ribosomal protein L11 methyltransferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_80_GENE_18 c hypo c hypoLeptoII_scaffold_80_GENE_19 c hypo c hypo (like thiol-disulfide isomerase)LeptoII_scaffold_80_GENE_20 c hypo c hypoLeptoII_scaffold_80_GENE_21 transporter [Inorganic ion transport and metabolism]LeptoII_scaffold_80_GENE_22 phosphate binding periplasmic protein, abundant ext. [Inorganic ion transport and metabolism]LeptoII_scaffold_80_GENE_23 hypo unique hypo uniqueLeptoII_scaffold_80_GENE_24 RuBisCO-like protein [Carbohyhrate transport and metabolism]LeptoII_scaffold_80_GENE_25 Mg-protoporphyrin IX monomethyl ester oxidative cyclase [Coenzyme metabolism]LeptoII_scaffold_80_GENE_26 2-hydroxy-6-oxo-2,4-heptadieneoate hydrolase/TPR domain [Coenzyme metabolism]

LeptoII-24LeptoII_scaffold_224_GENE_1 c hypo c hypoLeptoII_scaffold_224_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_224_GENE_3 DNA primase [DNA replication, recombination, and repair]LeptoII_scaffold_224_GENE_4 224-4=tRNA Met=223-5 RNA polymerase sigma factor rpoD [Transcription]LeptoII_scaffold_224_GENE_5 c hypo c hypoLeptoII_scaffold_224_GENE_6 RnaseH [DNA replication, recombination, and repair]LeptoII_scaffold_224_GENE_7 HD domain phosphohydrolase [General function prediction only]

LeptoII_scaffold_224_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_224_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_224_GENE_10 16S rRNA pseudouridine synthase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_224_GENE_11 heat shock protein [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_224_GENE_12 ABC transporter ATP-binding protein [General function prediction only]LeptoII_scaffold_288_GENE_7 hypo unique hypo unique (phosphohydrolase-like)LeptoII_scaffold_288_GENE_6 ribonuclease [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_288_GENE_5 xanthosine triphosphate pyrophosphatase [Nucleotide transport and metabolism]LeptoII_scaffold_288_GENE_4 beta-hexosaminidase [Carbohyhrate transport and metabolism]LeptoII_scaffold_288_GENE_3 glutamate racemase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_288_GENE_2 anthranilate synthase, component II [Amino acid transport and metabolism]LeptoII_scaffold_288_GENE_1 helicase [DNA replication, recombination, and repair]LeptoII_scaffold_175_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_175_GENE_2 c hypo c hypoLeptoII_scaffold_175_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_175_GENE_4 phosphoglycerate mutase [Carbohyhrate transport and metabolism]LeptoII_scaffold_175_GENE_5 lipoate synthase [Coenzyme metabolism]LeptoII_scaffold_175_GENE_6 HD-GYP hydrolase domain protein/response regulator [Signal transduction mechanisms]LeptoII_scaffold_175_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_175_GENE_8 glycogen debranching enzyme [Carbohyhrate transport and metabolism]LeptoII_scaffold_175_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_175_GENE_10 major facilitator superfamily transporter [General function prediction only]LeptoII_scaffold_175_GENE_11 metallo-beta-lactamase hydrolase [Defense mechanisms]LeptoII_scaffold_175_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_175_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_175_GENE_14 c hypo c hypo

LeptoII-25LeptoII_scaffold_428_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_428_GENE_2 c hypo c hypoLeptoII_scaffold_428_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_428_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_428_GENE_5 ferric uptake regulation protein [Inorganic ion transport and metabolism]LeptoII_scaffold_428_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_71_GENE_1 acriflavin resistance protein [Defense mechanisms]LeptoII_scaffold_71_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_71_GENE_3 polyA polymerase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_71_GENE_4 c hypo c hypo (like O-linked N-acetylglucosamine transferases)LeptoII_scaffold_71_GENE_5 exopolyphosphatase [Nucleotide transport and metabolism]LeptoII_scaffold_71_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_71_GENE_7 DNA helicase [DNA replication, recombination, and repair]LeptoII_scaffold_71_GENE_8 translational inhibitor [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_71_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_71_GENE_10 thioredoxin [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_71_GENE_11 cytochrome b subunit of bc complex (complex III) [Energy production and conversion]LeptoII_scaffold_71_GENE_12 cyt b/b6 complex, Fe-S subunit [Energy production and conversion]LeptoII_scaffold_71_GENE_13 enoyl acyl carrier protein [Lipid metabolism]LeptoII_scaffold_71_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_71_GENE_15 hypo unique hypo uniqueLeptoII_scaffold_71_GENE_16 DNA mismatch repair protein [DNA replication, recombination, and repair]LeptoII_scaffold_71_GENE_17 hypo unique hypo uniqueLeptoII_scaffold_71_GENE_18 uracil-DNA glycosylase/DNA polymerase [DNA replication, recombination, and repair]LeptoII_scaffold_71_GENE_19 hypo unique hypo uniqueLeptoII_scaffold_71_GENE_20 acyl-carrier protein synthase [Lipid metabolism]LeptoII_scaffold_71_GENE_21 pyridoxal phosphate biosynthetic protein [Coenzyme metabolism]LeptoII_scaffold_71_GENE_22 zinc protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_71_GENE_23 hypo unique hypo uniqueLeptoII_scaffold_71_GENE_24 nucleotidyltransferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_71_GENE_25 ribsomal protein S15 [Translation, ribosomal structure and biogenesis]

LeptoII-26LeptoII_scaffold_75_GENE_1 phage protein? c hypo c hypo (phage protein homology?)LeptoII_scaffold_75_GENE_2 transcriptional regulator, LexA family [Transcription]LeptoII_scaffold_75_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_75_GENE_4 DNA helicase [DNA replication, recombination, and repair]LeptoII_scaffold_75_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_75_GENE_6 pectin degradation protein [Carbohyhrate transport and metabolism]LeptoII_scaffold_75_GENE_7 SAM-dependent methyltransferase [Amino acid transport and metabolism]LeptoII_scaffold_75_GENE_8 caffeoyl-CoA O-methyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_75_GENE_9 T (single) transposase transposaseLeptoII_scaffold_75_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_75_GENE_11 hypo unique hypo unique

LeptoII_scaffold_75_GENE_12 T (single) transposase transposaseLeptoII_scaffold_75_GENE_13 c hypo c hypoLeptoII_scaffold_75_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_75_GENE_15 methyl-accepting chemotaxis protein [Cell motility and secretion]LeptoII_scaffold_75_GENE_16 flavoprotein/metallo-beta-lactamase family [Energy production and conversion]LeptoII_scaffold_75_GENE_17 methyl-accepting chemotaxis protein [Cell motility and secretion]LeptoII_scaffold_75_GENE_18 methyl-accepting chemotaxis protein [Cell motility and secretion]LeptoII_scaffold_75_GENE_19 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_75_GENE_20 flavoprotein/metallo-beta-lactamase family [Energy production and conversion]LeptoII_scaffold_75_GENE_21 glycoprotein [General function prediction only]LeptoII_scaffold_75_GENE_22 c hypo c hypoLeptoII_scaffold_75_GENE_23 caffeoyl-CoA O-methyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_75_GENE_24 hypo unique hypo uniqueLeptoII_scaffold_75_GENE_25 hypo unique hypo uniqueLeptoII_scaffold_75_GENE_26 integral membrane protein [General function prediction only]LeptoII_scaffold_75_GENE_27 c hypo c hypoLeptoII_scaffold_75_GENE_28 ABC transporter, ATP-binding protein [General function prediction only]LeptoII_scaffold_75_GENE_29 hypo unique hypo uniqueLeptoII_scaffold_75_GENE_30 hypo unique hypo uniqueLeptoII_scaffold_75_GENE_31 integrase fragment integrase fragment [DNA replication, recombination, and repair]

LeptoII-27LeptoII_scaffold_76_GENE_1 hypoxanthine-guanine phosphoribosyltransferase [Nucleotide transport and metabolism]LeptoII_scaffold_76_GENE_2 ATPase, cell cycle protein MesJ [Cell divison and chromosome partitioning]LeptoII_scaffold_76_GENE_3 riboflavin kinase/FAD synthase [Coenzyme metabolism]LeptoII_scaffold_76_GENE_4 delta-aminolevulinic acid dehydratase [Coenzyme metabolism]LeptoII_scaffold_76_GENE_5 uroporphyrinogen-III c-methyltransferase [Coenzyme metabolism]LeptoII_scaffold_76_GENE_6 porphobilinogen deaminase [Coenzyme metabolism]LeptoII_scaffold_76_GENE_7 glutamyl-tRNA reductase [Coenzyme metabolism]LeptoII_scaffold_76_GENE_8 cytochrome c biogenesis protein/ABC-type transport system [Coenzyme metabolism]LeptoII_scaffold_76_GENE_9 c hypo c hypo LeptoII_scaffold_76_GENE_10 lysine 2,3-aminomutase [Amino acid transport and metabolism]LeptoII_scaffold_76_GENE_11 nitroreductase [Energy production and conversion]LeptoII_scaffold_76_GENE_12 deoxycytidine triphosphate deaminase [Nucleotide transport and metabolism]LeptoII_scaffold_76_GENE_13 AAA-type ATPase [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_76_GENE_14 c hypo c hypo - suspect proteosome componentLeptoII_scaffold_76_GENE_15 hypo unique hypo uniqueLeptoII_scaffold_76_GENE_16 proteosome, beta subunit [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_76_GENE_17 hypo unique hypo unique (like proteosome, alpha subunit)LeptoII_scaffold_76_GENE_18 c hypo c hypo - suspect proteosome componentLeptoII_scaffold_76_GENE_19 dihydroorotase dehydrogenase [Nucleotide transport and metabolism]LeptoII_scaffold_76_GENE_20 homoserine kinase [Amino acid transport and metabolism]LeptoII_scaffold_76_GENE_21 ferredoxin [Energy production and conversion]LeptoII_scaffold_76_GENE_22 membrane protein [General function prediction only]LeptoII_scaffold_76_GENE_23 T5 transposase-like transposase

LeptoII-28LeptoII_scaffold_96_GENE_1 T6 transposase-like transposaseLeptoII_scaffold_96_GENE_2 96-1= tRNA Asp = 96-2 hypo unique hypo uniqueLeptoII_scaffold_96_GENE_3 TolQ biopolymer transport protein, ExbB [Intracellular trafficking and secretion]LeptoII_scaffold_96_GENE_4 biopolymer transport protein TolR, ExbD [Intracellular trafficking and secretion]LeptoII_scaffold_96_GENE_5 hypo unique hypo unique (faint similarity to TonB)LeptoII_scaffold_96_GENE_6 periplasmic TolB protein [Intracellular trafficking and secretion]LeptoII_scaffold_96_GENE_7 c hypo c hypoLeptoII_scaffold_96_GENE_8 DNA mismatch repair protein MutL [DNA replication, recombination, and repair]LeptoII_scaffold_96_GENE_9 tRNA delta-2-isopentenylpyrophosphate transferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_96_GENE_10 methylthioadenosine phosphorylase [Nucleotide transport and metabolism]LeptoII_scaffold_96_GENE_11 carbohydrate kinase [Carbohyhrate transport and metabolism]LeptoII_scaffold_96_GENE_12 cell division cycle protein Cdc57 [Cell motility and secretion]LeptoII_scaffold_96_GENE_13 c hypo c hypoLeptoII_scaffold_96_GENE_14 96-14=tRNA Thr= 96-15 hypo unique hypo uniqueLeptoII_scaffold_96_GENE_15 hypo unique hypo uniqueLeptoII_scaffold_96_GENE_16 c hypo c hypo (sim. to Holliday jxn. resolvases)LeptoII_scaffold_96_GENE_17 hypo unique hypo uniqueLeptoII_scaffold_96_GENE_18 hypo unique hypo uniqueLeptoII_scaffold_96_GENE_19 mobilization MobD mobilization protein, MobD [Cell divison and chromosome partitioning]LeptoII_scaffold_96_GENE_20 hypo unique hypo uniqueLeptoII_scaffold_96_GENE_21 hypo unique hypo uniqueLeptoII_scaffold_96_GENE_22 hypo unique hypo uniqueLeptoII_scaffold_96_GENE_23 plasmid protein TrwC TrwC plasmid protein [General function prediction only]

LeptoII-29LeptoII_scaffold_98_GENE_1 FtsH cell division protein/metalloprotease [Cell divison and chromosome partitioning]

LeptoII_scaffold_98_GENE_2 dihydropteroate synthase [Coenzyme metabolism]LeptoII_scaffold_98_GENE_3a c hypo c hypo found overlapping 98-3LeptoII_scaffold_98_GENE_3b c hypo c hypoLeptoII_scaffold_98_GENE_4 c hypo hypo LeptoII_scaffold_98_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_98_GENE_6 98-5=tRNA Asn=98-6 c hypo c hypo (faint similarity to ammonia monooxygenase)LeptoII_scaffold_98_GENE_7 isochorismatase [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_98_GENE_8 transcriptional regulator [Transcription]LeptoII_scaffold_98_GENE_9 Na+/H+ antiporter [Inorganic ion transport and metabolism]LeptoII_scaffold_98_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_98_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_98_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_98_GENE_13 fusaric acid detoxification protein/efflux transporter/permease [Defense mechanisms]LeptoII_scaffold_98_GENE_14 c hypo c hypoLeptoII_scaffold_98_GENE_15 HlyD family secretion protein, involved in multidrug resistance [Defense mechanisms]LeptoII_scaffold_98_GENE_16 hypo unique hypo uniqueLeptoII_scaffold_98_GENE_17 deoxyribodipyrimidine photolyase [DNA replication, recombination, and repair]LeptoII_scaffold_98_GENE_18 K+ channel protein [Inorganic ion transport and metabolism]LeptoII_scaffold_98_GENE_19 pirin-related protein [General function prediction only]

LeptoII-30LeptoII_scaffold_710_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_710_GENE_2 replication protein repC replication protein C [DNA replication, recombination, and repair]LeptoII_scaffold_710_GENE_3 replication protein repA (plasmid) replication protein A [DNA replication, recombination, and repair]LeptoII_scaffold_710_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_710_GENE_5 DNA helicase [DNA replication, recombination, and repair]LeptoII_scaffold_710_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_186_GENE_1 186-0=tRNA Gly=186-2 hypo unique (large protein)LeptoII_scaffold_186_GENE_2 hypo unique hypo unique, possible thiamine biosynthesis, ThiS LeptoII_scaffold_186_GENE_3 general secretion pathway GspC [Intracellular trafficking and secretion]LeptoII_scaffold_186_GENE_4 general secretion pathway GspD [Intracellular trafficking and secretion]LeptoII_scaffold_186_GENE_5 pili-related general secretion pathway, GspE [Intracellular trafficking and secretion]LeptoII_scaffold_186_GENE_6 general secretion pathway GspF [Intracellular trafficking and secretion]LeptoII_scaffold_186_GENE_7 general secretion pathway, GspG [Intracellular trafficking and secretion]LeptoII_scaffold_186_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_186_GENE_9 hypo unique hypo unique (GspL-like)LeptoII_scaffold_186_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_186_GENE_11 general secretion pathway, GspK [Intracellular trafficking and secretion]LeptoII_scaffold_186_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_186_GENE_13 hypo unique hypo unique

LeptoII-31LeptoII_scaffold_150_GENE_1 T5 transposase-like transposaseLeptoII_scaffold_150_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_150_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_150_GENE_4 ribonuclease III [Transcription]LeptoII_scaffold_150_GENE_5 DNA polymerase III, alpha subunit [DNA replication, recombination, and repair]LeptoII_scaffold_150_GENE_6 tRNA(5-methylaminomethyl-2-thiouridylate)-methyl transferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_150_GENE_7 c hypo c hypoLeptoII_scaffold_150_GENE_8 chromosome partitioning protein, ParB [Cell divison and chromosome partitioning]LeptoII_scaffold_150_GENE_9 chromosome partitioning protein, ParA [Cell divison and chromosome partitioning]LeptoII_scaffold_150_GENE_10 glucose inhibited division protein, GidB [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_150_GENE_11 glucose inhibited division protein, GidA [Cell divison and chromosome partitioning]LeptoII_scaffold_150_GENE_12 thiophene and furan oxidation protein [General function prediction only]LeptoII_scaffold_150_GENE_13 60kD inner membrane protein [Intracellular trafficking and secretion]LeptoII_scaffold_150_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_150_GENE_15 ribosomal protein L9 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_150_GENE_1 T6 transposase transposase

LeptoII-32LeptoI_scaffold_349_GENE_1 ribosomal protein S5 [Translation, ribosomal structure and biogenesis]LeptoI_scaffold_349_GENE_2 ribosomal protein L18 [Translation, ribosomal structure and biogenesis]LeptoI_scaffold_349_GENE_3 ribosomal protein L6 [Translation, ribosomal structure and biogenesis]LeptoI_scaffold_349_GENE_4 ribosomal protein S8 [Translation, ribosomal structure and biogenesis]LeptoI_scaffold_349_GENE_5 ribosomal protein L5 [Translation, ribosomal structure and biogenesis]LeptoI_scaffold_349_GENE_6 ribosomal protein L14 [Translation, ribosomal structure and biogenesis]LeptoI_scaffold_349_GENE_7 hypo unique hypo unique (ribosomal protein S17-like)LeptoI_scaffold_349_GENE_8 ribosomal protein L16 [Translation, ribosomal structure and biogenesis]LeptoI_scaffold_349_GENE_9 ribosomal protein S3 [Translation, ribosomal structure and biogenesis]LeptoI_scaffold_349_GENE_10 ribosomal protein L22 [Translation, ribosomal structure and biogenesis]LeptoI_scaffold_349_GENE_11 ribosomal protein S19 [Translation, ribosomal structure and biogenesis]LeptoI_scaffold_349_GENE_12 ribosomal protein L2 [Translation, ribosomal structure and biogenesis]LeptoI_scaffold_349_GENE_13 ribosomal protein L4 [Translation, ribosomal structure and biogenesis]

LeptoI_scaffold_349_GENE_14 ribosomal protein L3 [Translation, ribosomal structure and biogenesis]

LeptoII-33LeptoII_scaffold_167_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_167_GENE_2 DNA helicase [DNA replication, recombination, and repair]LeptoII_scaffold_167_GENE_3 DNA polymerase III alpha subunit [DNA replication, recombination, and repair]LeptoII_scaffold_167_GENE_4 carboxyl transferase alpha subunit [Lipid metabolism]LeptoII_scaffold_167_GENE_5 tryptophanyl tRNA synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_167_GENE_6 Zn-dependant protease [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_167_GENE_7 hypo unique hypo unique, possible branched chain amino acid transport proteinLeptoII_scaffold_167_GENE_8 c hypo c hypoLeptoII_scaffold_167_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_167_GENE_10 N-acetyl amidase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_167_GENE_1 167-11=tRNA Arg=167-11+ hypo unique hypo uniqueLeptoII_scaffold_775_GENE-2 repA similar to repA [DNA replication, recombination, and repair]LeptoII-1033-3 (wrong ORF?) hypo uniqueLeptoII_scaffold_1033_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_1033_GENE_1 hypo unique hypo unique

LeptoII-34LeptoII_scaffold_174_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_174_GENE_2 transcription termination factor [Transcription]LeptoII_scaffold_174_GENE_3 ribosomal protein L31 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_174_GENE_4 peptide chain release factor I [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_174_GENE_5 modification methylase, HemK [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_174_GENE_6 UDP-N-acetylglucosamine 1-carboxyvinyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_174_GENE_7 ATP phosphoribosyltransferase (histidine biosynthesis) [Amino acid transport and metabolism]LeptoII_scaffold_174_GENE_8 histidinol dehydrogenase [Amino acid transport and metabolism]LeptoII_scaffold_174_GENE_9 histidinol aminotransferase [Amino acid transport and metabolism]LeptoII_scaffold_174_GENE_10 imidazoleglycerol phosphate dehydrogenase [Amino acid transport and metabolism]LeptoII_scaffold_174_GENE_11 amidotransferase HisH [Amino acid transport and metabolism]LeptoII_scaffold_174_GENE_12 phosphoribosyl formimino-5-amidoimidazole isomerase [Amino acid transport and metabolism]LeptoII_scaffold_174_GENE_13 HisF cyclase [Amino acid transport and metabolism]LeptoII_scaffold_174_GENE_14 phosphoribosyl-AMP cyclohydrolase, HisIE [Amino acid transport and metabolism]LeptoII_scaffold_174_GENE_15 HIT family hydrolase [Nucleotide transport and metabolism]LeptoII_scaffold_174_GENE_16 nucleoid DNA-binding protein [DNA replication, recombination, and repair]LeptoII_scaffold_174_GENE_1 T5 transposase transposase

LeptoII-35LeptoII_scaffold_140_GENE_1 cold shock protein [Transcription]LeptoII_scaffold_140_GENE_2 hypo unique hypo unique (like general secretion pathway protein H)LeptoII_scaffold_140_GENE_3 general secretion pathway protein I [Intracellular trafficking and secretion]LeptoII_scaffold_140_GENE_4 general secretion pathway protein J [Intracellular trafficking and secretion]LeptoII_scaffold_140_GENE_5 replicative DNA helicase [DNA replication, recombination, and repair]LeptoII_scaffold_140_GENE_6 histidyl tRNA synthetase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_140_GENE_7 phosphoglycerate dehydrogenase [Amino acid transport and metabolism]LeptoII_scaffold_140_GENE_8 aminotransferase [Amino acid transport and metabolism]LeptoII_scaffold_140_GENE_9 oligopeptide ABC transporter, oligopeptide binding protein [Amino acid transport and metabolism]LeptoII_scaffold_140_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_140_GENE_1 140-11=5S, LSU rRNA=140-12 hypo unique hypo uniqueLeptoII_scaffold_140_GENE_1 140-12=Ala, Ile, SSU rRNA=140-12+ hypo unique hypo unique

LeptoII-36LeptoII_scaffold_178_GENE_1 hydroxyacylglutathione hydrolase [General function prediction only]LeptoII_scaffold_178_GENE_2 hypo unique hypo unique (similarity to transcriptional regulators)LeptoII_scaffold_178_GENE_3 major facilitator superfamily transporter [General function prediction only]LeptoII_scaffold_178_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_178_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_178_GENE_6 metal ion efflux protein, CzcC [Defense mechanisms]LeptoII_scaffold_178_GENE_7 efflux system transmembrane protein, CzrB [Defense mechanisms]LeptoII_scaffold_178_GENE_8 cation efflux system transmembrane protein, CzcA [Defense mechanisms]LeptoII_scaffold_178_GENE_9 hypo unique hypo unique (faint similarity to cation efflux pumps)LeptoII_scaffold_178_GENE_1 T5 transposase transposase

LeptoII-37LeptoII_scaffold_222_GENE_1a hypo unique hypo uniqueLeptoII_scaffold_222_GENE_1b hypo unique hypo unique overlaps gene 1LeptoII_scaffold_222_GENE_2 sensory box/GGDEF family protein [Signal transduction mechanisms]LeptoII_scaffold_222_GENE_3 S-adenosylmethionine carboxylase [Amino acid transport and metabolism]LeptoII_scaffold_222_GENE_4 spermidine synthase [Amino acid transport and metabolism]LeptoII_scaffold_222_GENE_5 argenine/lysine decarboxylase [Amino acid transport and metabolism]LeptoII_scaffold_222_GENE_6 c hypo c hypoLeptoII_scaffold_222_GENE_7 DNA repair protein RecN [DNA replication, recombination, and repair]LeptoII_scaffold_222_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_222_GENE_9 thioredoxin, abundant in extracellular [Posttranslational modification, protein turnover, chaperones]

LeptoII-38LeptoII_scaffold_234_GENE_1 DNA binding protein [General function prediction only]LeptoII_scaffold_234_GENE_2 biotin synthesis protein/methyltransferase [Coenzyme metabolism]LeptoII_scaffold_234_GENE_3 c hypo c hypoLeptoII_scaffold_234_GENE_4 acetolactate synthase small subunit [Amino acid transport and metabolism]LeptoII_scaffold_234_GENE_5 acetolactate synthase, large subunit [Amino acid transport and metabolism]LeptoII_scaffold_234_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_234_GENE_7 T (single) transposase (single) transposaseLeptoII_scaffold_234_GENE_8 pyoverdine chromophore precursor synthetase [Lipid metabolism]LeptoII_scaffold_234_GENE_9 T11 transposase transposase

LeptoII-39LeptoII_scaffold_261_GENE_1 T9 transposase transposaseLeptoII_scaffold_261_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_261_GENE_3 restriction endonuclease (plasmid) restriction endonuclease [Defense mechanisms]LeptoII_scaffold_261_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_261_GENE_5 c hypo c hypoLeptoII_scaffold_261_GENE_6 c hypo c hypoLeptoII_scaffold_261_GENE_7 T11 transposase transposaseLeptoII_scaffold_261_GENE_8 T9 transposase transposaseLeptoII_scaffold_261_GENE_9 T8 transposase transposaseLeptoII_scaffold_261_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_261_GENE_1 T11 transposase transposaseLeptoII_scaffold_261_GENE_12 hypo unique hypo unique

LeptoII-40LeptoII_scaffold_274_GENE_1 ribosomal protein S1 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_274_GENE_2 c hypo c hypo similar to DNA binding protein found overlapping 274-2LeptoII_scaffold_274_GENE_2 signal peptidase [Intracellular trafficking and secretion]LeptoII_scaffold_274_GENE_3 signal recognition particle protein [Intracellular trafficking and secretion]LeptoII_scaffold_274_GENE_4 Ribosomal protein S16 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_274_GENE_5 c hypo c hypo, possible RNA-binding proteinLeptoII_scaffold_274_GENE_6 tRNA methytransferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_274_GENE_7 ribosomal protein L19 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_274_GENE_8 ribonuclease HII [DNA replication, recombination, and repair]LeptoII_scaffold_274_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_274_GENE_10 lipoprotein [General function prediction only]

LeptoII-41LeptoII_scaffold_341_GENE_1 T16 transposase transposaseLeptoII_scaffold_341_GENE_2 sim to T16 transposase transposaseLeptoII_scaffold_341_GENE_3 c hypo c hypoLeptoII_scaffold_341_GENE_4 acetyltransferase [General function prediction only]LeptoII_scaffold_341_GENE_5 c hypo c hypoLeptoII_scaffold_341_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_341_GENE_7 c hypo c hypoLeptoII_scaffold_341_GENE_8 isonitrile hydratase, ThiJ [Coenzyme metabolism]LeptoII_scaffold_341_GENE_9 c hypo c hypoLeptoII_scaffold_341_GENE_10 c hypo c hypoLeptoII_scaffold_341_GENE_11 c hypo c hypoLeptoII_scaffold_341_GENE_12 acetyltransferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_341_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_341_GENE_14 dipeptidyl peptidase IV [Amino acid transport and metabolism]

LeptoII-42LeptoII_scaffold_369_GENE_1 T5 transposase-like transposaseLeptoII_scaffold_369_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_369_GENE_3 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_369_GENE_4 T5 transposase-like transposaseLeptoII_scaffold_369_GENE_5 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_369_GENE_6 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_369_GENE_7 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_369_GENE_8 ABC transporter permease protein [Carbohyhrate transport and metabolism]LeptoII_scaffold_369_GENE_9 ABC transporter ATP-binding protein [Carbohyhrate transport and metabolism]

LeptoII-43LeptoII_scaffold_376_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_376_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_376_GENE_3 c hypo c hypoLeptoII_scaffold_376_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_376_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_376_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_376_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_376_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_376_GENE_9 hypo unique hypo unique

LeptoII_scaffold_376_GENE_10 hypo unique hypo unique found in alternative reading frameLeptoII_scaffold_376_GENE_1 phage-related c hypo c hypoLeptoII_scaffold_376_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_376_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_376_GENE_14 hypo unique hypo unique found in alternative reading frameLeptoII_scaffold_376_GENE_15 hypo unique hypo unique

LeptoII-44LeptoII_scaffold_1042_GENE_ T8 c hypo c hypoLeptoII_scaffold_1042_GENE_2 hypo unique tiny hypoLeptoII_scaffold_219_GENE_1 c hypo c hypoLeptoII_scaffold_219_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_219_GENE_3 c hypo c hypoLeptoII_scaffold_219_GENE_4 possible plasmid integration site? c hypo c hypoLeptoII_scaffold_219_GENE_5 integrase fragment integrase fragment (Rci type) WHOLE ONE MUST OCCUR! [DNA replication, recombination, and repair]LeptoII_scaffold_219_GENE_6 219-6 = tRNA Gly = 219-7 hypo unique hypo unique (outer membrane lipoprotein-like)LeptoII_scaffold_219_GENE_7 integrase integrase [DNA replication, recombination, and repair]LeptoII_scaffold_219_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_219_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_219_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_219_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_219_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_219_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_219_GENE_14 c hypo c hypoLeptoII_scaffold_219_GENE_1 MobD mobilization protein, MobD [Cell divison and chromosome partitioning]LeptoII_scaffold_219_GENE_1 MobE mobilization protein, MobE [Cell divison and chromosome partitioning]LeptoII_scaffold_219_GENE_17 hypo unique hypo uniqueLeptoII_scaffold_219_GENE_1 TraA mobilization protein, TraA [Cell divison and chromosome partitioning]

LeptoII-45LeptoII_scaffold_412_GENE_1 T9 transposase transposaseLeptoII_scaffold_412_GENE_2 T8 transposase-like transposaseLeptoII_scaffold_412_GENE_3 c hypo c hypoLeptoII_scaffold_412_GENE_4 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_412_GENE_5 T (single) transposase (single) transposaseLeptoII_scaffold_412_GENE_6 T (single, copy in LeptoIII) transposase transposase

LeptoII-46LeptoII_scaffold_429_GENE_1 429-1=tRNA Thr =425-0 hypo unique hypo uniqueLeptoII_scaffold_429_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_429_GENE_3 ribosomal protein L9 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_429_GENE_4 T5 transposase transposaseLeptoII_scaffold_429_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_429_GENE_6 T5 hypo unique hypo uniqueLeptoII_scaffold_429_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_429_GENE_8 T (single) transposase transposase

LeptoII-47LeptoII_scaffold_435_GENE_1 integrase Rci integrase [DNA replication, recombination, and repair]LeptoII_scaffold_435_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_435_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_435_GENE_4 transcriptional activator [Transcription]LeptoII_scaffold_435_GENE_5 T5 transposase transposaseLeptoII_scaffold_435_GENE_6 transcriptional activator [Transcription]LeptoII_scaffold_435_GENE_7 autoinducer biosynthetic protein/LuxI-type quorum sensing regulator [Signal transduction mechanisms]LeptoII_scaffold_435_GENE_8 c hypo c hypoLeptoII_scaffold_435_GENE_9 NADH dehydrogenase I, F subunit [Energy production and conversion]

LeptoII-48LeptoII_scaffold_467_GENE_1 tRNA-pseudouridine synthase B [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_467_GENE_2 hypo unique hypo unique (like ribosome binding factor A)LeptoII_scaffold_467_GENE_3 c hypo c hypoLeptoII_scaffold_467_GENE_4 translation initiation factor [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_467_GENE_5 nitrogen utilization substance protein A [Transcription]LeptoII_scaffold_467_GENE_6 c hypo c hypo found in alt. ORF, uncharacterize BCR, YhbC family

LeptoII-49LeptoII_scaffold_482_GENE_1 ..- rod shape determining protein, MreB [Cell divison and chromosome partitioning]LeptoII_scaffold_482_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_482_GENE_3 rod shape determining protein, MreC [Cell divison and chromosome partitioning]LeptoII_scaffold_482_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_482_GENE_5 cell division protein FtsI [Cell divison and chromosome partitioning]LeptoII_scaffold_482_GENE_6 rod shape determining protein, RodA [Cell divison and chromosome partitioning]LeptoII_scaffold_482_GENE_7 ribonuclease G [Translation, ribosomal structure and biogenesis]

LeptoII-50LeptoII_scaffold_511_GENE_1 hypo unique hypo unique

LeptoII_scaffold_511_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_511_GENE_3 hypo unique hypo unique found in alternative reading frame (contains gap)LeptoII_scaffold_511_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_511_GENE_5a hypo unique hypo unique found in alternative reading frameLeptoII_scaffold_511_GENE_5b hypo unique hypo uniqueLeptoII_scaffold_511_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_511_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_511_GENE_8 glucokinase [Carbohyhrate transport and metabolism]LeptoII_scaffold_511_GENE_9 hypo unique hypo unique

LeptoII-51LeptoII_scaffold_526_GENE_1 T (single) transposase transposaseLeptoII_scaffold_526_GENE_2 T15 transposase (single) transposaseLeptoII_scaffold_526_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_526_GENE_4 hypo unique hypo unique, possible TDP-glocose-4,6-dehydrataseLeptoII_scaffold_526_GENE_5 dTDP-4-dehydrorhamnose 3,5-epimerase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_526_GENE_6 UDP-glucose-4-epimerase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_526_GENE_7 epimerase/dehydratase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_526_GENE_8 alpha-D-glucose-1-phosphate cytidylyltransferase [Cell envelope biogenesis, outer membrane]

LeptoII-52LeptoII_scaffold_569_GENE_1 motB chemotaxis motB protein [Cell motility and secretion]LeptoII_scaffold_569_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_569_GENE_3 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_569_GENE_4 TraI plasmid? TraI [Intracellular trafficking and secretion]LeptoII_scaffold_569_GENE_5 DotB (type II secretion) [Intracellular trafficking and secretion]

LeptoII-53LeptoII_scaffold_817_GENE_1 hypo uniqueLeptoII_scaffold_817_GENE_2 hypo unique hypo unique (like Zn-dependent hydrolases)

new? LeptoII_scaffold_817_GENE_3 c hypo c hypo (SAM-dependent methyltransferase-related)LeptoII_scaffold_817_GENE_4 c hypo c hypo (SAM-dependent methyltransferase-related)LeptoII_scaffold_592_GENE_1 c hypo c hypoLeptoII_scaffold_592_GENE_2 c hypo c hypoLeptoII_scaffold_592_GENE_3 N-acetyl transferase [General function prediction only]LeptoII_scaffold_592_GENE_4 c hypo c hypoLeptoII_scaffold_592_GENE_5 hydrolase [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_592_GENE_6 c hypo c hypoLeptoII_scaffold_592_GENE_7 N-acetyl transferase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_592_GENE_8 c hypo c hypoLeptoII_scaffold_592_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_592_GENE_1 antibiotic-like phenazine biosynthesis protein [General function prediction only]

new? LeptoII_scaffold_1059_GENE_2 N-acyl homoserine lactone transcriptional regulator [Signal transduction mechanisms]LeptoII_scaffold_1059_GENE_ T transposase-like transposase

LeptoII-54LeptoII_scaffold_616_GENE_1 N-acyl homoserine /quorum sensing [Signal transduction mechanisms]LeptoII_scaffold_616_GENE_2 cytochrome P450 [Secondary metabolites biosynthesis, transport, and catabolisLeptoII_scaffold_616_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_616_GENE_4 T11 transposase transposaseLeptoII_scaffold_616_GENE_5 T11 transposase transposase

LeptoII-55LeptoII_scaffold_713_GENE_4 ribosomal protein S12 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_713_GENE_3 ribosomal protein S7 [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_713_GENE_2 elongation factor EF-G FusA GTPase [Translation, ribosomal structure and biogenesis]LeptoII_scaffold_713_GENE_1 translation elongation factor (duplicated) [Translation, ribosomal structure and biogenesis]

LeptoII-56LeptoII_scaffold_630_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_630_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_630_GENE_3 hypo unique hypo unique (630-3, 865-2)LeptoII_scaffold_630_GENE_4 T (single) transposase transposaseLeptoII_scaffold_630_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_630_GENE_6 hypo unique hypo unique, similar to cyt c (63% to L3:181-2)

LeptoII-57LeptoII_scaffold_684_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_684_GENE_2 c hypo c hypoLeptoII_scaffold_684_GENE_3 c hypo c hypoLeptoII_scaffold_684_GENE_4 c hypo c hypoLeptoII_scaffold_684_GENE_5 c hypo c hypoLeptoII_scaffold_684_GENE_6 c hypo c hypo

LeptoII-58LeptoII_scaffold_689_GENE_1 c hypo c hypoLeptoII_scaffold_689_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_689_GENE_3 cytochrome c551 (59% to 8-58) [Energy production and conversion]

LeptoII_scaffold_689_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_689_GENE_5 RNA helicase [DNA replication, recombination, and repair]LeptoII_scaffold_689_GENE_6 glutamine amidotransferase [General function prediction only]

LeptoII-59LeptoII_scaffold_706_GENE_1 c hypo c hypoLeptoII_scaffold_706_GENE_2 DNA primase [DNA replication, recombination, and repair]LeptoII_scaffold_706_GENE_3 c hypo c hypoLeptoII_scaffold_706_GENE_4 hypo unique hypo unique found in alternative reading frameLeptoII_scaffold_706_GENE_5 phage integrase P4 integrase P4 [DNA replication, recombination, and repair]

LeptoII-60LeptoII_scaffold_708_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_708_GENE_2 T (single, copy in LeptoIII) transposase transposaseLeptoII_scaffold_708_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_708_GENE_4 glycosyltransferase [Cell envelope biogenesis, outer membrane]LeptoII_scaffold_708_GENE_5 hypo unique hypo unique

LeptoII-61LeptoII_scaffold_728_GENE_1 c hypo c hypoLeptoII_scaffold_728_GENE_2 c hypo c hypoLeptoII_scaffold_728_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_728_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_728_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_728_GENE_6 hypo unique hypo unique (like thiol-disulfide interchange protein, DsbG)LeptoII_scaffold_728_GENE_7 methyltransferase/restriction modification system [Defense mechanisms]

LeptoII-62LeptoII_scaffold_745_GENE_1 IcmB [General function prediction only]LeptoII_scaffold_745_GENE_2 IcmB (isobutyryl-CoA mutase) [Energy production and conversion]LeptoII_scaffold_745_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_745_GENE_4 hypo unique hypo unique

LeptoII-63LeptoII_scaffold_759_GENE_1 ATP-dependent protease La [Posttranslational modification, protein turnover, chaperones]LeptoII_scaffold_759_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_759_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_759_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_759_GENE_5 RNA helicase [DNA replication, recombination, and repair]

LeptoII-64LeptoII_scaffold_824_GENE_1 T5 hypo unique probable transposase transposaseLeptoII_scaffold_824_GENE_2 methyl-accepting chemotaxis transducer [Cell motility and secretion]LeptoII_scaffold_824_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_824_GENE_4 c hypo c hypo

LeptoII-65LeptoII_scaffold_830_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_830_GENE_2 c hypo c hypoLeptoII_scaffold_830_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_830_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_830_GENE_5 helicase [Transcription]

LeptoII-66LeptoII_scaffold_865_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_865_GENE_2 hypo unique hypo unique LeptoII_scaffold_865_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_865_GENE_4 permease [General function prediction only]

LeptoII-67LeptoII_scaffold_869_GENE_1 c hypo c hypoLeptoII_scaffold_869_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_869_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_869_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_869_GENE_5 hypo unique hypo unique

LeptoII-68LeptoII_scaffold_888_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_888_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_888_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_888_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_888_GENE_5 c hypo c hypoLeptoII_scaffold_888_GENE_6 c hypo c hypo

LeptoII-69LeptoII_scaffold_985_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_985_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_985_GENE_3 cytochrome c biogenesis protein, CcsA [Coenzyme metabolism]LeptoII_scaffold_985_GENE_4a hypo unique hypo unique (larger than initially annotated)LeptoII_scaffold_985_GENE_4b

LeptoII-70: 784-0=tRNA Arg=784-1LeptoII_scaffold_784_GENE_1 integrase fragment integrase (fragment, no domain) [DNA replication, recombination, and repair]

new? LeptoII_scaffold_784_GENE_2 integrase Rci integrase [DNA replication, recombination, and repair]LeptoII_scaffold_1145_GENE_ pili biogenesis pili biogenesis protein [Cell divison and chromosome partitioning]LeptoII_scaffold_1145_GENE_2 hypo unique hypo unique

dupl prev LeptoII_scaffold_784_GENE_5 hypo unique hypo unique

LeptoII-71LeptoII_scaffold_1147_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_1147_GENE_2 ssDNA binding protein [DNA replication, recombination, and repair]LeptoII_scaffold_1147_GENE_ TraE topoisomerase TraE [DNA replication, recombination, and repair]LeptoII_scaffold_1147_GENE_4 hypo unique hypo unique

LeptoII-72LeptoII_scaffold_483_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_483_GENE_2 ..- mercuric reductase (differs from others in community) [Defense mechanisms]LeptoII_scaffold_483_GENE_3 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]

LeptoII-73LeptoII_scaffold_1153_GENE_ T11 transposase transposaseLeptoII_scaffold_1153_GENE_2 helicase [DNA replication, recombination, and repair]

LeptoII-74LeptoII_scaffold_645_GENE_1 cellulose synthase CelB [Carbohyhrate transport and metabolism]LeptoII_scaffold_645_GENE_2 cellulase [Carbohyhrate transport and metabolism]LeptoII_scaffold_645_GENE_3 cellulose synthase, subunit C [Carbohyhrate transport and metabolism]LeptoII_scaffold_645_GENE_4 cellulose synthase, subunit C [Carbohyhrate transport and metabolism]

POSSIBLE PLASMID (pp) FRAGMENTS

pp1 LeptoII_scaffold_454_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_454_GENE_2 T (single) transposase transposaseLeptoII_scaffold_454_GENE_3a c hypo c hypoLeptoII_scaffold_454_GENE_3b hypo unique hypo unique found overlapping 454-3LeptoII_scaffold_454_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_454_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_454_GENE_6 Colonization AcfB plasmid?? accessory colonization factor/methyl-accepting chemotaxis protei [Cell motility and secretion]LeptoII_scaffold_454_GENE_8 T5 transposase transposaseLeptoII_scaffold_81_GENE_2 methyl-accepting chemotaxis protein [Cell motility and secretion]LeptoII_scaffold_81_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_81_GENE_4 T6 transposase transposaseLeptoII_scaffold_81_GENE_5 methyl-accepting chemotaxis protein [Cell motility and secretion]LeptoII_scaffold_81_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_81_GENE_7 c hypo c hypoLeptoII_scaffold_81_GENE_8 c hypo c hypoLeptoII_scaffold_81_GENE_9 c hypo c hypoLeptoII_scaffold_81_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_81_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_81_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_81_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_81_GENE_14 integrase, partial Rci domain integrase/recombinase [DNA replication, recombination, and repair]LeptoII_scaffold_81_GENE_15 shufflon-specific recomb., Rci recombinase [DNA replication, recombination, and repair]LeptoII_scaffold_81_GENE_16 c hypo c hypoLeptoII_scaffold_81_GENE_17 hypo unique hypo uniqueLeptoII_scaffold_81_GENE_18 hypo unique hypo uniqueLeptoII_scaffold_81_GENE_19 CzcC has been found on plasmids. heavy metal efflux protein, CzcC [Defense mechanisms]LeptoII_scaffold_81_GENE_20 CzcB metal efflux syst. heavy metal efflux protein, CzcB [Defense mechanisms]LeptoII_scaffold_81_GENE_21 CzcA metal efflux syst. heavy metal efflux protein, CzcA [Defense mechanisms]LeptoII_scaffold_81_GENE_22 hypo unique hypo uniqueLeptoII_scaffold_81_GENE_23 hypo unique hypo uniqueLeptoII_scaffold_81_GENE_24 phage protein? hypo unique hypo uniqueLeptoII_scaffold_81_GENE_25 hypo unique hypo unique (identical to 627-4)LeptoII_scaffold_81_GENE_26 conjugal transfer TraA conjugal transfer protein, TraA [DNA replication, recombination, and repair]LeptoII_scaffold_81_GENE_27 con tran TraD conjugal transfer protein, TraD [DNA replication, recombination, and repair]LeptoII_scaffold_115_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_115_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_115_GENE_4 MobD mobilization mobilization protein, MobD [Cell divison and chromosome partitioning]LeptoII_scaffold_115_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_115_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_115_GENE_7 c hypo c hypoLeptoII_scaffold_115_GENE_8 transcriptional regulator [Transcription]LeptoII_scaffold_115_GENE_9 DNA primase [DNA replication, recombination, and repair]LeptoII_scaffold_115_GENE_10 hypo unique hypo unique

LeptoII_scaffold_115_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_115_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_115_GENE_13 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_115_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_115_GENE_15 hypo unique hypo uniqueLeptoII_scaffold_115_GENE_16 c hypo c hypoLeptoII_scaffold_115_GENE_17 c hypo c hypoLeptoII_scaffold_115_GENE_18 c hypo c hypoLeptoII_scaffold_115_GENE_1 T (single) transposase transposaseLeptoII_scaffold_115_GENE_2 resolvase TnpR (found on plasmids) resolvase [DNA replication, recombination, and repair]LeptoII_scaffold_115_GENE_21 hypo unique hypo uniqueLeptoII_scaffold_115_GENE_22 ABC transporter, ATP-binding protein [General function prediction only]LeptoII_scaffold_115_GENE_2 T7 transposase transposaseLeptoII_scaffold_808_GENE_2 T (single) transposase transposaseLeptoII_scaffold_808_GENE_3 T (single) transposase transposaseLeptoII_scaffold_808_GENE_4 c hypo c hypoLeptoII_scaffold_579_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_579_GENE_2 T10 (all pl-rel) transposase transposaseLeptoII_scaffold_579_GENE_3 T7 (all pl-rel) transposase transposaseLeptoII_scaffold_579_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_579_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_579_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_579_GENE_7 T17 (related to plasmid tr) transposase transposase

pp2 LeptoII_scaffold_170_GENE_1 c hypo c hypoLeptoII_scaffold_170_GENE_2 T transposase transposaseLeptoII_scaffold_170_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_170_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_170_GENE_5 plasmid TrwC TrwC plasmid protein/DNA helicase [DNA replication, recombination, and repair]LeptoII_scaffold_170_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_170_GENE_7 plasmid protein TrwB TrwB plasmid protein [Intracellular trafficking and secretion]LeptoII_scaffold_170_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_170_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_170_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_170_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_170_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_170_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_170_GENE_1 phage protein? c hypo c hypoLeptoII_scaffold_170_GENE_15 hypo unique hypo uniqueLeptoII_scaffold_294_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_294_GENE_6 replication protein A/helicase [DNA replication, recombination, and repair]LeptoII_scaffold_294_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_294_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_294_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_294_GENE_2 c hypo c hypoLeptoII_scaffold_212_GENE_1 phage integrase Rci (plasmid) integrase [DNA replication, recombination, and repair]LeptoII_scaffold_212_GENE_16 H+-transporting ATPase [Inorganic ion transport and metabolism]LeptoII_scaffold_212_GENE_1 phage integrase Rci (plasmid) recombinase/integrase [DNA replication, recombination, and repair]LeptoII_scaffold_212_GENE_14 c hypo c hypoLeptoII_scaffold_212_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_212_GENE_12 type I restriction system adenine methylase [Defense mechanisms]LeptoII_scaffold_212_GENE_11 c hypo c hypoLeptoII_scaffold_212_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_212_GENE_9 c hypo c hypoLeptoII_scaffold_212_GENE_8 c hypo c hypoLeptoII_scaffold_212_GENE_7 c hypo c hypoLeptoII_scaffold_212_GENE_6 nucletidyltransferase [Cell divison and chromosome partitioning]LeptoII_scaffold_212_GENE_5 type I restriction system, specificity protein [Defense mechanisms]LeptoII_scaffold_212_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_212_GENE_3 DNA damage inducible protein J [DNA replication, recombination, and repair]LeptoII_scaffold_212_GENE_2 c hypo c hypoLeptoII_scaffold_212_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_918_GENE_3 type I restriction helicase [DNA replication, recombination, and repair]LeptoII_scaffold_918_GENE_4 type I restriction helicase [DNA replication, recombination, and repair]

pp3 LeptoII_scaffold_815_GENE_1 T5 transposase-like transposaseLeptoII_scaffold_815_GENE_2815-1=tRNA Leu=815-2 integrase Rci integrase [DNA replication, recombination, and repair]LeptoII_scaffold_815_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_815_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_815_GENE_5a hypo unique hypo unique found overlapping 815-5

LeptoII_scaffold_815_GENE_5b mobilization protein TraI/Trwc [Cell divison and chromosome partitioning]LeptoII_scaffold_600_GENE_1 DNA helicase [DNA replication, recombination, and repair]LeptoII_scaffold_600_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_600_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_600_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_600_GENE_5 conjugation TrwB TrwB conjugal transfer protein [Intracellular trafficking and secretion]LeptoII_scaffold_185_GENE_1 plasmid coupling TrwB plasmid coupling protein Trwb [Intracellular trafficking and secretion]LeptoII_scaffold_185_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_15 biopolymer transport, ExbD [Intracellular trafficking and secretion]LeptoII_scaffold_185_GENE_16 c hypo c hypo, possible periplasmic protein TonB, links inner & outer memb.LeptoII_scaffold_185_GENE_17 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_18 biopolymer transport, TolQ [Intracellular trafficking and secretion]LeptoII_scaffold_185_GENE_19 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_20 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_21 hypo unique hypo uniqueLeptoII_scaffold_185_GENE_22 c hypo c hypoLeptoII_scaffold_265_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_265_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_265_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_265_GENE_5 phage /ICE, Rec or IntP4 domain phage-related integrase [DNA replication, recombination, and repair]LeptoII_scaffold_265_GENE_6 c hypo c hypoLeptoII_scaffold_265_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_265_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_265_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_265_GENE_1 T8 transposase-like transposaseLeptoII_scaffold_265_GENE_1 T9 transposase transposaseLeptoII_scaffold_265_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_265_GENE_1 integrase, Rci integrase [DNA replication, recombination, and repair]LeptoII_scaffold_265_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_265_GENE_15 hypo unique hypo unique

pp4 LeptoII_scaffold_582_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_582_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_582_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_582_GENE_5 PilT can be on plasmids pillus assembly protein/twitching motility protein [Cell motility and secretion]LeptoII_scaffold_582_GENE_4 PilT pilus assembly pillus assembly protein/twitching motility protein [Cell motility and secretion]LeptoII_scaffold_582_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_582_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_440_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_440_GENE_5 conjugal TraG conjugal transfer protein TraG [Intracellular trafficking and secretion]LeptoII_scaffold_440_GENE_4 conjugal TraG conjugal transfer protein TraG [Intracellular trafficking and secretion]LeptoII_scaffold_440_GENE_3 conjugal TrbB conjugal transfer protein TrbB [Intracellular trafficking and secretion]LeptoII_scaffold_259_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_259_GENE_2 conjugal TrbE conjugal transfer protein TrbE [Intracellular trafficking and secretion]LeptoII_scaffold_259_GENE_3 TrbE conjugal transfer protein TrbE [Intracellular trafficking and secretion]LeptoII_scaffold_259_GENE_4 TrbJ conjugal transfer protein TrbJ [Intracellular trafficking and secretion]LeptoII_scaffold_259_GENE_5 TrbL conjugal transfer protein TrbL [Intracellular trafficking and secretion]LeptoII_scaffold_259_GENE_6 TrbF conjugal transfer protein TrbF [Intracellular trafficking and secretion]LeptoII_scaffold_259_GENE_7 TrbG conjugal transfer protein TrbG [Intracellular trafficking and secretion]LeptoII_scaffold_259_GENE_8 TrbI conjugal transfer protein TrbI [Intracellular trafficking and secretion]LeptoII_scaffold_259_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_259_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_259_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_259_GENE_12 HD-GYP hydrolase domain protein/response regulator [Signal transduction mechanisms]

pp5 LeptoII_scaffold_173_GENE_1 repA (plasmid) replication protein A [DNA replication, recombination, and repair]LeptoII_scaffold_173_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_173_GENE_3 hypo unique hypo unique

LeptoII_scaffold_173_GENE_4 T (single) transposase transposaseLeptoII_scaffold_173_GENE_5 T (single) transposase transposaseLeptoII_scaffold_173_GENE_6 c hypo c hypoLeptoII_scaffold_173_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_173_GENE_8 hypo unique hypo uniqueLeptoII_scaffold_173_GENE_9 hypo unique hypo uniqueLeptoII_scaffold_173_GENE_1 T (single) transposase transposaseLeptoII_scaffold_173_GENE_11 lstB helper protein/transposase transposaseLeptoII_scaffold_173_GENE_12 hypo unique hypo uniqueLeptoII_scaffold_173_GENE_13 c hypo c hypoLeptoII_scaffold_173_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_173_GENE_1 T9 transposase transposaseLeptoII_scaffold_173_GENE_1 T8 transposase-like transposaseLeptoII_scaffold_173_GENE_17 hypo unique hypo uniqueLeptoII_scaffold_173_GENE_18 hypo unique hypo unique

pp6 LeptoII_scaffold_829_GENE_6 TraC TraC [Cell divison and chromosome partitioning]LeptoII_scaffold_829_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_829_GENE_4 hypo hypo uniqueLeptoII_scaffold_829_GENE_3 hypo hypo uniqueLeptoII_scaffold_232_GENE_14 hypo unique hypo uniqueLeptoII_scaffold_232_GENE_1 like MobE hypo unique hypo unique (like mobilization protein MobE)LeptoII_scaffold_232_GENE_12 c hypo c hypoLeptoII_scaffold_232_GENE_1 T17 (related to plasmid tr) transposase transposaseLeptoII_scaffold_232_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_232_GENE_9 c hypo c hypoLeptoII_scaffold_232_GENE_8 c hypo c hypoLeptoII_scaffold_232_GENE_7 hypo unique hypo unique (possible defect in organelle trafficking protein DotA)LeptoII_scaffold_232_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_232_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_232_GENE_4 ABC transporter ATP-binding protein [General function prediction only]LeptoII_scaffold_232_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_232_GENE_2 c hypo c hypoLeptoII_scaffold_232_GENE_1 ABC transporter ATP-binding protein [General function prediction only]

pp7 LeptoII_scaffold_245_GENE_1 sensory box/GGDEF domain/EAL domain protein [Signal transduction mechanisms]LeptoII_scaffold_245_GENE_2 plasmid transfer TraF plasmid transfer protein TraF [Cell divison and chromosome partitioning]LeptoII_scaffold_245_GENE_3 conjugal TraB conjugal transfer protein TraB [Cell divison and chromosome partitioning]LeptoII_scaffold_245_GENE_4 2-acylglycerophosphoethanolamine acyltransferase [Lipid metabolism]LeptoII_scaffold_245_GENE_5 short-chain dehydrogenase [General function prediction only]LeptoII_scaffold_245_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_245_GENE_7 isonitrile hydratase [Transcription]LeptoII_scaffold_245_GENE_8 type II restriction endonuclease [Defense mechanisms]LeptoII_scaffold_245_GENE_9 DNA methyltransferase [DNA replication, recombination, and repair]LeptoII_scaffold_245_GENE_10 hypo unique hypo uniqueLeptoII_scaffold_245_GENE_11 hypo unique hypo uniqueLeptoII_scaffold_245_GENE_12 alcohol dehydrogenase [General function prediction only]LeptoII_scaffold_245_GENE_13 hypo unique hypo uniqueLeptoII_scaffold_245_GENE_14 transcriptional regulator [Transcription]LeptoII_scaffold_245_GENE_1 ParB can be on plasmids chromosome partitioning protein ParB [Cell divison and chromosome partitioning]LeptoII_scaffold_245_GENE_1 ParA can be on plasmids plasmid replication protein, ParA [Cell divison and chromosome partitioning]

pp8 LeptoII_scaffold_478_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_478_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_478_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_478_GENE_4 plasmid helicase TrwC TrwC plasmid protein/DNA helicase [DNA replication, recombination, and repair]LeptoII_scaffold_478_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_478_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_478_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_478_GENE_8 c hypo c hypo

pp9 LeptoII_scaffold_490_GENE_1 ..- hypo unique hypo uniqueLeptoII_scaffold_490_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_490_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_490_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_490_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_490_GENE_6 T (single) transposase transposaseLeptoII_scaffold_490_GENE_7 hypo unique hypo uniqueLeptoII_scaffold_490_GENE_8 T (single) transposase transposaseLeptoII_scaffold_490_GENE_9 hypo unique hypo unique

LeptoII_scaffold_490_GENE_1 repC replication protein C [DNA replication, recombination, and repair]LeptoII_scaffold_490_GENE_1 repA replication protein A [DNA replication, recombination, and repair]

pp10 LeptoII_scaffold_898_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_898_GENE_2 MobC mobilization protein, MobC [Cell divison and chromosome partitioning]LeptoII_scaffold_898_GENE_3 MobD mobilization protein, MobD [Cell divison and chromosome partitioning]LeptoII_scaffold_898_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_898_GENE_5 MobE mobilization protein MobE [Cell divison and chromosome partitioning]LeptoII_scaffold_898_GENE_6 hypo unique hypo uniqueLeptoII_scaffold_898_GENE_7 TrwC DNA helicase/TrwC [DNA replication, recombination, and repair]

pp11 LeptoII_scaffold_673_GENE_1 DNA primase [DNA replication, recombination, and repair]LeptoII_scaffold_673_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_673_GENE_3 c hypo c hypoLeptoII_scaffold_673_GENE_4 hypo unique hypo uniqueLeptoII_scaffold_673_GENE_5 hypo unique hypo uniqueLeptoII_scaffold_673_GENE_6 MobA mobilization relaxase, MobA [Cell divison and chromosome partitioning]LeptoII_scaffold_847_GENE_1 c hypo c hypo (TraD-like)

pp12 LeptoII_scaffold_402_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_402_GENE_2 MobD ATPase involved in ABC transporters [General function prediction only]LeptoII_scaffold_402_GENE_3 hypo unique hypo uniqueLeptoII_scaffold_402_GENE_4 DNA primase (phage?) DNA primase [DNA replication, recombination, and repair]LeptoII_scaffold_402_GENE_5 hypo unique hypo unique

pp13 LeptoII_scaffold_811_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_811_GENE_2 relaxase/mobilization protein, MobA [Cell divison and chromosome partitioning]LeptoII_scaffold_811_GENE_3 type IV secretory pathway [Intracellular trafficking and secretion]

pp14 LeptoII_scaffold_751_GENE_1 ssDNA binding protein [DNA replication, recombination, and repair]LeptoII_scaffold_751_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_751_GENE_3 DNA repair protein RadC [DNA replication, recombination, and repair]LeptoII_scaffold_751_GENE_4 VirD relaxase/mobilization protein [DNA replication, recombination, and repair]LeptoII_scaffold_751_GENE_5 c hypo c hypoLeptoII_scaffold_751_GENE_6 c hypo c hypo

pp15 LeptoII_scaffold_637_GENE_1 hypo unique hypo uniqueLeptoII_scaffold_637_GENE_2 hypo unique hypo uniqueLeptoII_scaffold_637_GENE_3 TraA conjugal transfer protein TraA [DNA replication, recombination, and repair]LeptoII_scaffold_637_GENE_4 hypo unique hypo unique