ColinB.Josephson,M.D.,M.Sc.,F.R.C.P.C.,CSCN(EEG)

CurriculumVitae I.BIOGRAPHICALDATAName: ColinBruceJosephsonAddress: FoothillsMedicalCentre

Office3E45,TeachingResearchandWellnessBld.Calgary,AB,Canada,T2N2T9

Telephone: +1(403)220-4289Email: cbjoseph@ucalgary.caPresentrank: AssistantProfessorofNeurologyPrimaryDepartment: ClinicalNeurosciencesSecondaryDepartment: CommunityHealthSciencesFaculty: MedicineInstitution: UniversityofCalgaryII.ACADEMICRECORDOngoingdegree MastersofEpidemiologyDateexpected May2018Specialty EpidemiologyInstitution/City/Country UniversityofCalgary,Calgary,Canadai.Undergraduate Medicaldegree(MD)Datecompleted May2006Specialty MedicineInstitution/City/Country DalhousieUniversity,Halifax,Canada

BachelorofScience(Honours)Datecompleted April2000Specialty BiologyInstitution/City/Country Queen’sUniversity,Kingston,Canada

ii.SpecialProfessional NeurologyFRCP(C)Datecompleted June2013Specialty NeurologyInstitution/City/Country DalhousieUniversity,Halifax,Canadaiii.Graduateandpost-doctoral VisitingResearchScholarDatecompleted December2015Specialty BigDataresearchandanalyticsInstitution/City/Country FarrInstitute;UniversityCollegeLondon,London,UK

ClinicalResearchFellowDatecompleted June2013Specialty EpilepsyandEEGInstitution/City/Country UniversityofCalgary,Calgary,Canada

ClinicalResearchFellowDatecompleted February2011Specialty IntracranialVascularMalformationsInstitution/City/Country UniversityofEdinburgh,Edinburgh,UnitedKingdom

MastersofScience(Dean’sListHonours)Datecompleted September2003Specialty PhysiologyTitleofthesis Determination of sites in the Na(+)/H(+) Exchanger

Isoform1(NHE1)involvediniontranslocationSupervisor Dr.JohnOrlowskiInstitution/City/Country McGillUniversity,Montreal,Canadaiv.Licensure,certification,boards 2015-present CanadianSocietyforClinicalNeurophysiology(EEG)

certification2013-present CollegeofPhysiciansandSurgeonsofAlberta2013-present Fellow of the Royal College of Physicians and

SurgeonsofCanada2013-present Specialist Certificate, Neurology, Royal College of

PhysiciansandSurgeonsofCanada2009-2011 UnitedKingdomGeneralMedicalCouncil

2007-present LicentiateoftheMedicalCouncilofCanada(LMCC)2006-2013 NovaScotiaCollegeofPhysiciansandSurgeonsIII.AWARDSANDDISTINCTIONS2018 Named to theUniversityofCalgary’sHonourRollof

OutstandingUndergraduateMedicalTeaching2017 Acceptedintothe2017CanadianInstitutesofHealth

Research (CIHR) Early Career Investigators GrantReviewProgram

2017 Accepted intothe2017 InternationalLeagueAgainstEpilepsy(ILAE)LeadershipProgram

2016 12th European Congress on Epilepsy HighlyCommended Certificate for Poster Presentation of‘Adverse psychological effects of levetiracetamcompared to seven other common anti-epilepticdrugsinadultswithepilepsyingeneralpractice’

2015 AlbertaInnovationandAdvancedEducationGraduateStudentScholarshipfor$3000.00

2014 American Brain Foundation/American Academy ofNeurology/American Epilepsy Society/EpilepsyFoundation Susan S. Spencer Clinical ResearchTrainingFellowshipinEpilepsy

2014 Alberta Innovates Health Solutions (AIHS) ClinicianFellowshiprecipient

2013 CanadianInstitutesHealthResearch(CIHR)Fellowshiprecipient

2013 AmericanEpilepsySocietyFellowTravelAward2013 CanadianSocietyofClinicalNeurophysiologists(CSCN)

National Clinical Fellowship in Epilepsy andElectroencephalography

2013 Canadian League Against Epilepsy Mary Ann LeeAward for best neurology or neurosurgery residentresearch

2012 Dalhousie University Neurosciences Research Daybestoralpresentation

2011 Dalhousie University Faculty of Medicine ResearchDayDMAAAwardforbestoralpresentation

2011 Dalhousie University Department of MedicineResearchDayawardforbestoralpresentation

2010 European Stroke Conference Young Investigator oftheYearAward.

2010 Royal College of Physicians London ‘InternationalAdvisors as Partners: Models of Collaboration’Meetingawardforposterpresentation

2010 AngiomaAllianceTravelAward2006 Richard Payzant Ward Travel Bursary to attend the

CanadianCongressofNeurologicalSciences2006 DalhousieUniversityGrahamGwynMemorialPrizein

Neurology2006 DalhousieInternationalHealthOfficeTravelBursary2005 Recipient of Top Poster Presentation Prize at the

DalhousieFacultyofMedicineStudentResearchDay2004 Canadian Cardiovascular Academy “Have a Heart

Bursary”2003 AwardedDean’sListHonoursongraduationwithan

M.Sc.fromMcGillUniversity2002 Awarded runner-up for oral presentation at the 8th

Annual McGill University Department of PhysiologyGraduateStudentsResearchDay

2001 Awardedrunner-upforposterpresentationatthe7thAnnual McGill University Department of PhysiologyGraduateStudentsResearchDay

2000 Awarded the Faculty of Graduate Studies andResearch Fellowship as the top-ranked incominggraduate student toMcGill University’s DepartmentofPhysiology

2000 Ontario University Athletics (OUA) Academic All-OntarioStatus

1999 Ontario University Athletics (OUA) Academic All-OntarioStatus

1997-2001 MemberoftheQueen'sUniversityVarsityCurlingTeam

1997 AwardedDean'sListStatusatAcadiaUniversity1997 Recipient of the Clarke K. McLeod Pre-Medical

ScholarshipatAcadiaUniversity1996 Awarded a mid-year scholarship for academic

achievementatAcadiaUniversity

IV.ACADEMICAPPOINTMENTS2017-present MemberoftheDenaxasLaboratoryattheUniversity

of College London and Farr Institute of HealthInformaticsResearch

2016-present FullMember;HotchkissBrain Institute,University ofCalgary

2016-present Full Member; O’Brien Institute of Public Health,UniversityofCalgary

2016-present AssistantProfessorofNeurology;UniversityofCalgary2013-2015 Clinical Research Fellow in Epilepsy; University of

Calgary2011-2012 Co-ChiefResidentinNeurology;DalhousieUniversity2009-2011 ClinicalResearchFellowinVascularMalformationsof

theBrain;UniversityofEdinburghV.EDUCATIONALACTIVITIESi.Undergraduate 2017- UniversityofCalgaryFacultyofMedicineclassroom

lectureronepilepsyforCourseV:IntegratedNeurosciences,SpecialSensesandAging

2017- EvaluationchairoftheUniversityofCalgaryFacultyofMedicinecourseMDCN440:AppliedEvidenceBasedMedicine

2017- UniversityofCalgaryMDCN440:AppliedEvidenceBasedMedicinesmallgrouppreceptor

2015- UniversityofCalgaryClinicalCoreCourseV:IntegratedNeurosciences,SpecialSensesandAgingpreceptorforsmallgroupteachingofmedicalstudents

2014- UniversityofCalgaryClinicalCoreCourseV:IntegratedNeurosciences,SpecialSensesandAgingpreceptorforclinicalskillsteachingformedicalstudents

2008 TutorforDalhousieMedicalSchoolsmallgroupEpidemiologytutorials

2006-2013 InstructorforDalhousiesecondyearmedicalstudentclinicalskillsunit

2006-2012 ResponsibleforsupervisingmedicalstudentsrotatingthroughClinicalNeurology

2002 Teaching Assistant for Introductory PhysiologyLaboratoryCourseatMcGillUniversity

ii.Resident2016- PreparedandinvigilatedepilepsyOSCEsforresidents

fromthePGY-1to-5level2016- Mentored residents during their 3-month Epilepsy

Rotationincludinginclinic,readingEEGs,andontheSeizureMonitoringUnit

2016- University of Calgary Neurology Continuum Roundsfacilitator

2015- University of CalgaryNeurology Residents’ ‘Spot thebraincell’lectures

iii.Continuingmedicaleducation2017- Co-organiser for the Annual International Banff

EpilepsySymposium2017- Co-organiser for the 2017 1st Annual University of

Calgary’sCMEaccreditedCourseEpilepsyandSeizureManagement:BeyondtheER

iv.Supervision2018- Mr. Will Wilson; Master of Science candidate

(supervisorycommitteemember)2017-2018 Ms. Sanjana Sudershan; undergraduate Bachelor of

Health Sciences student project (co-supervised withDr.PamelaRoachforcourseMDSC507)

2017- Mr. KevinPerera; undergraduateBachelorofHealth

Sciences student project (co-supervised with Dr.NathalieJetteforcourseMDSC528)

2017 Ms.AyshaLukmanji;undergraduatesummerstudentfrom McGill University (co-supervised with Dr.NathalieJette)

2017 Mr.ConnorBranch;undergraduate summer student

from Carleton University (co-supervised with Dr.NathalieJette)

2016-2017 Ms. Ana Subota; undergraduate Bachelor of Health

Sciences student project (co-supervised with Dr.NathalieJetteforcourseMDSC507)

VI.ADMINISTRATIVERESPONSIBILITIESi.Departmental 2018 MemberoftheSearchandSelectionCommittee

foraNeurointensivistwithcross-appointmentsinNeurologyandCriticalCareattheUniversityofCalgary

2017- HeadoftheCalgaryComprehensiveEpilepsyProgramRegistry/ResearchProject

2017- FellowshipDirectorfortheUniversityofCalgary’sDivisionofEpilepsy

2017- Co-DirectorofEducationfortheUniversityofCalgary’sDivisionofEpilepsy

2017 MemberoftheSearchandSelectionCommitteeforanacademicadultepileptologistattheUniversityofCalgary

2016- Co-chairoftheDivisionofNeurologyResidentResearchSub-CommitteeoftheResidencyProgramCommittee

2011-2012 Co-chiefresidentfortheDivisionofNeurology2011-2012 MemberoftheDalhousieAdultNeurology

Resident-in-TrainingCommittee2008 MemberoftheinterviewcommitteeforDalhousie

AdultNeurologyResidencyProgram2003-2004 DalhousieUniversityMedIIClassRepresentative

fortheElectivesBlockoftheSchoolCurriculum2001-2002 PresidentoftheMcGillUniversityPhysiology

GraduateStudentAssociation

ii.Faculty 2017- EvaluationChairforUniversityofCalgaryFacultyof

MedicinecourseMDCN440:AppliedEvidence-BasedMedicine

2003-2004 Co-chairofthe2004AtlanticMedicalSchoolconferenceheldinHalifax,NS

2001-2002 Department of Physiology representative to theFacultyofGraduateStudies&Research

iii.University 2005-2006 MemberoftheinterviewcommitteeforDalhousie

MedicalSchooladmissions2001-2002 McGillUniversityPost-GraduateStudentSociety

(PGSS)Councilor1998 Memberoftheorganizingandleadershipteamof

theNewExchangeandTransferStudentOrientationWeek(NEWTS)atQueen'sUniversity

VII.PROFESSIONALACTIVITIESi.Membershipinprofessionalandlearnedsocieties

2015-present Canadian Society for Clinical Neurophysiology (EEG)certification

2013-present Fellow of the Royal College of Physicians andSurgeonsofCanada

2013-present CollegeofPhysiciansandSurgeonsofAlberta2013-present AlbertaMedicalAssociation2012-present AmericanEpilepsySociety2012-present CanadianLeagueAgainstEpilepsy2009-2011 GeneralMedicalCouncil2007-present LicentiateoftheMedicalCouncilofCanada(LMCC)2007-present AmericanAcademyofNeurology2007-present CanadianMedicalAssociation2007-present MedicalCouncilofCanada

ii.Professionalservice

Journalreview(adhoc)Completed1) Neurology2) CanadianMedicalAssociationJournal3) Stroke4) AdvancesinClinicalNeuroscienceandRehabilitation5) BritishMedicalJournal6) McMasterOnlineRatingofEvidence(MORE)7) CochraneDatabaseofSystematicReviews8) CanadianJournalofNeurologicalSciences9) JournalofNeurology,Neurosurgery,andPsychiatry10) ActaNeurologicaScandinavica11) EpilepsiaOpen12) Seizure13) BMJOpen14) JournaloftheNeurologicalSciences15) EpilepsyResearch16) Epilepsy&Behavior

Grantreview(adhoc)Completed2018 CIHRInstituteofNeurosciences,MentalHealthandAddiction2018 UnitedKingdomStrokeAssociation2017 UnitedKingdomStrokeAssociation2017 Office of the Associate Dean Research, University of Calgary, preliminary

reviewofCIHRSPORiCTRewardingSuccessInitiativeapplications.

Nationalandinternationalcommittees2018 InternationalPopulationDataLinkageNetwork(IPDLN) ConferenceReviewCommittee 2017- CanadianBoardofRegistrationofElectroencephalographTechnologists,

Inc.(C.B.R.E.T.,Inc.)Examiner2017- MemberoftheInternationalLeagueAgainstEpilepsyTaskForceonBig

Data/OpenData(ChairedbyDr.SamdenLhatoo) 2017- MemberoftheInternationalLeagueAgainstEpilepsySub-TaskForceon

Driving(ChairedbyDr.NathalieJette)2014-2016 CanadianLeagueAgainstEpilepsy(CLAE)JuniorMemberRepresentative

VIII.RESEARCHANDSALARYAWARDSUPPORTAmount Fundingagency Year(s)of

fundingProject/Activity

55,000.00(CAD) CFNCatalystGrantCompetition

2018-2019 TheEDGARstudy(ElderlywithepilepsyDruGAppRopriateness)

15,000.00(CAD) UniversityResearchGrantsCommitteeSeedGrant

2018 Creatingaprecisionmedicinepipelinefortheneurosciences

15,000.00(CAD) HotchkissBrainInstitute

2018 UseofCOX-2andCalciumChannelBlockersandepilepsyoutcomesinlarge,linkedelectronichealthrecords

102,000.00(CAD) UCBCanadaInc. 2018 Pan-CanadianObservationalStudyonEpilepsy(POSE)

3000.00(CAD) AlbertaInnovationandAdvancedEducationGraduateStudentScholarship

2015 MastersofEpidemiology

130,000.00(USD) AmericanBrainFoundation/AmericanEpilepsySociety/EpilepsyFoundation/AmericanAcademyofNeurology

2014-2016 SusanS.SpencerClinicalResearchTrainingFellowshipinEpilepsy

210,000.00(CAD) AlbertaInnovates:HealthSolutions

2014-2017 AlbertaInnovates:HealthSolutionsClinicianFellowship

165,000.00(CAD) CanadianInstitutesofHealthResearch

2013-2016 CanadianInstitutesofHealthResearchFellowship

65,000.00(CAD) CanadianSocietyofClinicalNeurophysiologists

2013 CanadianSocietyofClinicalNeurophysiologistsClinicalFellowshipinEpilepsyandElectroencephalography

IXINVITEDADDRESSESi.Invitedtalks2018 13thAnnualEuropeanCongressonEpileptology

• Session co-chair: Enabling precision medicine inepilepsythroughbighealthdataanalytics

• Presentation: Large, linked electronic andadministrative data and the epidemiology ofepilpesy

2018 53rd Annual Canadian Neurological Sciences

FederationCongress• A practical and clinically relevant review of the

newestgenerationAEDs2018 Invitedlecturesatl'UniversitédeMontréal,Montreal

• Grand rounds: Psychiatric comorbidities inepilepsy:thinkoutsidetheseizure

• Epilepsy rounds: Harnessing routine clinical datatoimproveefficiencyandadvanceresearch

2018 NationalEpilepsyReviewCourse(NERC)

• Presentation:Approachtoafirstseizure• Presentation:Medicalcomorbiditiesinepilepsy

2017 71stAnnualAmericanEpilepsySocietyMeeting

• Presentation: Epilepsy or just getting old?Diagnosticchallengesinelderly

2017 3rdAnnualAlbertaPROMsandEQ-5DResearchand

SupportUnit(APERSU)AnnualEnd-usermeeting• Presentation: EQ-5D scores in a large, hospital-

basedregistryofepilepsypatients2017 6thAnnualCampusAlbertaNeuroscienceSymposium

• Presentation:Bigdata andadvancedanalytics inepilepsy

2017 Hotchkiss Brain Institute-Melbourne Epilepsy

Symposium• Presentation: Linked Electronic Medical Records

as a Means of Studying the Epidemiology ofEpilepsy

2017 20th AnnualWestern EpilepsyWorkshop, Banff, AB,

Canada• Presentation: Some like it hot: a red (or scarlet)

herringoracauseofseizures?2016 7thAnnualCalgary Epilepsy Symposium,Calgary,AB,

Canada• Presentation: Some like it hot: a red (or scarlet)

herringoracauseofseizures?2016 7thAnnualCalgary Epilepsy Symposium,Calgary,AB,

Canada• Presentation:Thebest laidschemesofmiceand

mengooftawry:Theperilsofautoimmunity2016 Canadian League Against Epilepsy Biennial Meeting,

QuebecCity,QC,Canada• ModeratorfortheStatisticsinMedicinecourse• Presentation: An approach to meta-analytic

studies2016 Hotchkiss Brain Institute Research Day, Calgary, AB,

Canada• Big data in epilepsy: can Goliath finally conquer

David?2015 Canadian Epilepsy Research Initiative, Toronto, ON,

Canada• Bigdata:canGoliathfinallyconquerDavid?

2010 ScottishAuditof IntracranialVascularMalformations

10yearCelebration,Edinburgh,UK• Theriskofepilepticseizureafterthediagnosisof

acavernousorarteriovenousmalformations

2010 Annual Scottish Epilepsy Nurses Association (ESNA)

Meeting,Edinburgh,UK• Theriskofepilepticseizureandaclinicalauditof

patientcareafterthediagnosisofacavernousorarteriovenousmalformations

2007 DalhousieUniversityDepartmentofMedicineGrandRounds,Halifax,NS,Canada• FitsorFaints?

ii.Interviews 2018 NeurologyToday

• Causes, Mimics, and Pitfalls of Epilepsy in theElderly

2017 MedscapeNeurology

• Epileptic Activity Discovered in Late-OnsetAlzheimer's

2017 MedPageToday• The Effects of Mood and Anxiety Disorders in

Patients with Epilepsy: Could undetecteddepression or anxiety be the reason achievingseizurecontrolinpatientswithepilepsycanbesodifficult?

2017 ReutersHealth

• Associationofdepressionandtreateddepressionwith epilepsy and seizure outcomes: a multi-cohortanalysis.

2017 MedPageToday

• Associationofdepressionandtreateddepressionwith epilepsy and seizure outcomes: a multi-cohortanalysis.

X.PUBLICATIONS/PRESENTATIONSi.Peer-reviewedpublications1. WahbyS,KarnikV,SajobiTT,WiebeS,JosephsonCB.Cannabisuseisassociatedwith

worsehealthoutcomesinpeoplewithepilepsy:aprospectivecohortstudy.SubmittedtoNeurology.

2. JosephsonCB, Engbers J, Jette,N, Patten S, Sajobi, TT,MarshallD, LowerisonM, andWiebe S. Prescription trends and psychiatric symptoms following first prescription forseven common antiepileptic drugs in general practice Submitted to Epilepsy andBehavior.

3. SpringAM,PittmanDJ,Agha-KhaniY,JirschJ,PillayN,Bello-EspinosaLE,JosephsonCB,and Federico P. Interrater reliability and generalizability of high frequency oscillationevaluations.SubmittedtoFrontiersofNeurology.

4. Lukmanji S, SauroKM, JosephsonCB,AlturaKC,WiebeS, and JetteN.A Longitudinalcohort study on the impact of the clobazam shortage on patients with epilepsy.Epilepsia.2017Dec7.doi:10.1111/epi.13974.[Epubaheadofprint]

5. Josephson CB, Gonzalez-Izquierdo A, Denaxas S, Fitzpatrick N, Sajobi T, Engbers JDT,

Patten S, Jette N, and Wiebe S. Serotonin reuptake inhibitor use and mortality inepilepsy: findings from a contemporary linked electronic health records cohort study.Epilepsia.2017;58(11):2002-2009.

6. JosephsonCBandJette,N.Psychiatriccomorbiditiesinepilepsy.InternationalReviewof

Psychiatry.2017;29(5):409-424.

7. JosephsonCB,PattenSB,BullochA,WilliamsJVA,LavoratoD,FiestKM,andJetteN.Theimpactofseizuresonepilepsyoutcomes:anational,community-basedsurvey.Epilepsia.2017;58(5):764-771.

8. Josephson CB, Lowerison M, Vallerand I, Sajobi TT, Patten S, Jette N, and Wiebe S.

Associationofdepressionandtreateddepressionwithepilepsyandseizureoutcomes:amulti-cohortanalysis.JAMANeurology.2017;74(5):533-39.

9. FishmanJ,CohenG,JosephsonCB,CollierM,BharathamS,ZhangY,andWildI.Patientemotionsandperceptionsofantiepilepticdrugchangesandtitrationduringtreatmentforepilepsy.EpilepsyandBehavior.2017;69:44-52.

10. SpringA,PittmanDJ,Agha-KhaniA,JirschJ,PillayN,Bello-EspinosaLE,JosephsonCB,andFedericoP.Interraterreliabilityofvisuallyevaluatedhighfrequencyoscillations.ClinicalNeurophysiology.2017;128(3):433-41.

11. JosephsonCB,Sandy,S,Jette,N,Sajobi,TT,MarshallD,andWiebeS.Asystematicreview

ofclinicaldecisionrulesforepilepsy.EpilepsyandBehavior.2016;57(PtA):69-76• Editorialforthisarticle:PughMJ.Clinicaldecisionrulesforepilepsycare:Thecase

forthinkingbig.EpilepsyandBehavior2016;57(PtA):220-1

12. JosephsonCB,EngbersJ,JetteN,Agha-KhaniY,FedericoP,HansonA,MurphyW,PillayN, andWiebe S. Towards a clinically informed, data driven definition of elderly-onsetepilepsy.Epilepsia.2016;57(2):298-305

13. JosephsonCB,EngbersJ,JetteN,Agha-KhaniY,FedericoP,HansonA,MurphyW,PillayN, andWiebe S. An investigation into the psychosocial effects of the postictal state.Neurology.2016;86(8):723-30

14. Josephson CB*, Sauro K*, Clement F, Wiebe S, and Jette N. Medical versus invasive

therapyinAVM-relatedepilepsy:systematicreviewandmeta-analysis.Neurology.2015;86(1):64-71

• *=co-firstauthors15. JosephsonCB,RosenowF, andAl-Shahi SalmanR. Intracranial vascularmalformations

andepilepsy.SeminarsinNeurology.2015;35(3):223-234

16. SamarasekeraN,LerpiniereC,FonvilleAF,FarrallAJ,WardlawJM,WhitePM,TorgersenA,IronsideJW,SmithC,Al-ShahiSalmanR,LothianAuditoftheTreatmentofCerebralHaemorrhage (LATCH) collaborators (including Josephson, C). Consent for brain tissuedonationafter intracerebralhaemorrhage:acommunity-basedstudy.PLoSOne.2015;10(8):e0135043

17. Jinadasa T*, Josephson CB*, Boucher A, and Orlowski J. Determinants of Cation

Permeation and Drug Sensitivity in Predicted Transmembrane Helix 9 and AdjoiningExofacialRe-Entrant Loop5ofNa+/H+ExchangerNHE1. Journal. JournalofBiologicalChemistry.2015;290(29):18173-86

• *=co-firstauthors18. Josephson CB, White PM, Krishan A, Al-Shahi Salman R. Computed tomography

angiography ormagnetic resonance angiography for detection of intracranial vascular

malformations in patients with intracerebral haemorrhage. Stroke Cochrane Corner.2015;46:e2-e3

19. Josephson CB, White PM, Krishan A, Al-Shahi Salman R. Computed tomographyangiography ormagnetic resonance angiography for detection of intracranial vascularmalformations in patients with intracerebral haemorrhage. Cochrane Database ofSystematic Reviews 2014, Issue 9. Art. No.: CD009372. DOI:10.1002/14651858.CD009372.pub2.

20. MoultrieF,HorneMA,JosephsonCB,HallJM,CounsellCE,WarlowCP,PapanastassiouV,Murray GD, Al-Shahi Salman R and the Scottish Audit of Intracranial VascularMalformations collaborators. Outcome after surgical or conservative management ofcerebral cavernous malformations: prospective, population-based cohort study.Neurology.2014;83(7):582-589

• Editorialforthisarticle:BernardiniGLandStapfC.Cavernomatoday:Keepthesurgeonaway?Neurology.2014;83(7):576-577.

21. Al-Shahi SalmanR,WhitePM,CounsellCE,duPlessis J, vanBeijnum J, JosephsonCB,WilkinsonT,WedderburnCJ,SallonZ,BhattacharyaJJ,PapanastassiouV,St.GeorgeEJ,RitchieV,RobertsRC,SellarRJ,WarlowCPandtheScottishAuditofIntracranialVascularMalformationscollaborators.Outcomeafterconservativemanagementortreatmentofunruptured brain arteriovenous malformations or associated arterial aneurysms:prospective,population-basedcohortstudy.JAMA.2014;311(16):1661-1669

22. JosephsonCB,DykemanJ,FiestKM,LiuX,SadlerRM,JetteN,andWiebeS.Systematicreview and meta-analysis of standard vs selective temporal lobe epilepsy surgery.Neurology.2013;80(18):1669-1676.

• Editorialforthisarticle:MathernGWandMillerJW.Outcomesfortemporallobeepilepsyoperationsmaynotbeequal:AcallforanRCTofATLvsSAHNeurology.2013;80(18):1630-1631.

• PatientPageforthisarticle:KarceskiS.Temporallobeepilepsysurgery:Whatisthebestapproach?/AboutEpilepsy.Neurology.2013;80(18):e192-e194.

23. Josephson CB, Bhattacharya JJ, Counsell CE, Papanastassiou V, Ritchie V, Roberts RC,Sellar R, Warlow CP, and Al-Shahi Salman R. Seizure risk with AVM treatment orconservativemanagement:prospective,populationbasedstudy.Neurology.2012;79(6):500-507.

• Editorial for this article: Stapf C. Interventional AVM therapy against epilepticseizures:TreatmentbetweenScyllaandCharybdis?Neurology.2012;79(6):492-493.

24. JosephsonCBandPohlmann-EdenB.The“natural”historyofmedicallytreatedtemporal

lobe epilepsy: what can an evidence-based approach tell us? Epilepsy Research andTreatment.2012;vol212,ArticleID216510

25. Al-Shahi Salman R, Hall JM, Horne MA, Moultrie F, Josephson CB, Bhattacharya JJ,CounsellCE,MurrayGD,PapanastassiouV,RitchieV,RobertsRC,SellarRJ,WarlowCP.The untreated clinical course of cerebral cavernous malformations: prospective,population-basedcohortstudy.LancetNeurology.2012;11(3):217-224

26. Josephson CB, Leach JP, Duncan R, Roberts RC, Counsell CE, and Al-Shahi Salman R.Seizure risk from cavernous or arteriovenous malformations: prospective population-basedstudy.Neurology.2011;76(18):1548-1554.

• Editorialforthisarticle:HauserWAandMohrJP.Seizures,epilepsy,andvascularmalformations.Neurology.2011;76:1540-1541

27. JosephsonCB,FrantziasJ,SamarasekeraN,andAl-ShahiSalmanR.Thepersistingburdenofintracerebralhaemorrhage:caneffectivetreatmentsbefound?PLoSMedicine.2010;7(10):e1000353

28. JosephsonCBandAl-ShahiSalmanR.CananiPhoneapphelpstrokephysicians?LancetNeurology.2010;9(8):765

29. JosephsonCB,Al-AzriS,SmythDJ,HaaseD,and JohnstonBL.AcaseofPott’sdiseasewith epidural abscess andprobable cerebral tuberculoma followingBacillus Calmette-Guerin therapy for superficial bladder cancer. Can J Infect DisMedMicrobiol. 2010;21(1):e75-78

30. Josephson CB, Grant I, and Benstead T. Opsoclonus-myoclonus with multipleparaneoplasticsyndromesandVGCCantibodies.CanJNeurolSci.2009;36(4):512-514

31. JosephsonCB,PhillipsSJ,andAl-ShahiSalmanR.BMJEndgames:Anepisodeoftransientneurologicalsymptoms.AreviewofthediagnosisandmanagementofTIAs.BMJ.2009;338:b616.

32. JosephsonCB,DelgadoD,SchiffJ,andRossH.Theeffectivenessofrenaltransplantationasatreatmentforrecurrenturemiccardiomyopathy.CanJCardiol.2008;24(4):315-317

33. Josephson CB, Rahey S, and Sadler RM. Neurocardiogenic syncope: frequency andconsequencesofitsmisdiagnosisofepilepsy.CanJNeurolSci.2007;34:221-224

34. JosephsonCB,HowlettJG,JacksonSD,FinleyJ,andKellsCM.Acaseseriesofsystemic

right ventricular dysfunction post atrial switch for simple D-transposition of the greatarteries:theimpactofbeta-blockade.CanJCardiol.2006;22(9):769-772.

ii.Books,chapter1. JosephsonCBandWiebeS.Chapter3:Medication-resistantepilepsy:Ananalysisofthe

definitionanditsuse.2016in:STERN&SPERLING:Medication-ResistantEpilepsy

2. JosephsonCBandAl-ShahiSalmanR.Chapter9:Haemorrhage:newandrecurrent.In:Rigamonti, D, editor. 2011 in: Cavernous Malformations of the Nervous System.Cambridge:CambridgeUniversityPress

iii.Presentations/abstracts1. WahbyS,KarnikV,Wiebe,S,andJosephsonCB.Cannabisuseandpatientreported

outcomemeasuresinaprospective,tertiary-carecohortofpatientswithepilepsy.Submittedtothe2018EuropeanCongressonEpileptology.

2. KhanS,SubotaA,SudershanS,JetteN,BranchC,LukmanjiA,WiebeS,andJosephsonCB.Biomarkersinthepostictalstate:asystematicreviewandmeta-analysis.Submittedtothe2018EuropeanCongressonEpileptology.

3. WahbyS,KarnikV,SajobiTT,WiebeS,JosephsonCB.Cannabisuseandpatientreportedoutcomemeasuresinaprospective,tertiary-carecohortofpeoplewithepilepsy.CalgaryComprehensiveResearchDayRetreat,Calgary,AB,Canada,March2018(platformpresentation).

4. SudershanS,KhanS,SubotaA,LukmanjiA,BranchC,RoachP,JetteN,WiebeS,BuchhalterJ;FedericoP,TeskeyGC,andJosephsonCB.Biomarkersinthepostictalstate:asystematicreviewandmeta-analysis.CalgaryComprehensiveResearchDayRetreat,Calgary,AB,Canada,March2018(platformpresentation).

5. KhanS,SubotaA,LukmanjiS,JetteN,RoachP,WiebeS,BuchhalterJ,FedericoP,TeskeyGC,JosephsonCB.ASystematicReviewandMeta-AnalysisofSignsandSymptomsofthePost-IctalStateinEpilepsy.CalgaryComprehensiveResearchDayRetreat,Calgary,AB,Canada,March2018(platformpresentation).

6. GelfandJ,LeeJ,KhanS,CrooksR,JosephsonCB,WiebeS,PattenS,KorngutL,SmithE,andRoachP.Patientperspectivesregardingknowledgegapsandresourcesforepilepsy:

Aqualitativestudy.CalgaryComprehensiveResearchDayRetreat,Calgary,AB,Canada,March2018(platformpresentation).

7. SajobiTT,MenonBK,JosephsonCB,HillMD,QuanH,andWiebeS.Acomparisonofcost

sensitivemachinelearningclassifiersforpredictingrareoutcomes.WesternCanadaUniversitiesBigDataHealthConference,Banff,AB;September2017(posterpresentation).

8. LukmanjiS,SauroK,JosephsonCB,WiebeS,NurseS,andJetteN.ALongitudinalCohortStudyontheImpactoftheClobazamShortageonPatientswithEpilepsy:APatientPerspective.CanadianLeagueAgainstEpilepsyBiennialMeeting,Vancouver,BC;October2017(posterpresentation)

9. LethbeGC,JosephsonCB,WiebeS,LowerisonMW,LethbeBC,andWilliamsonT.EffectofadmittancetotheSeizureMonitoringUnitonaggregatehealthcareresourceutilization.CampusAlbertaStudentsConferenceonHealth(CASCH;Banff,Canada)September2017(posterpresentation)

10. JosephsonCB,Gonzalez-IzquierdoA,DenaxasS,FitzpatrickN,SajobiT,EngbersJ,PattenS,JetteN,andWiebeS.Serotoninreuptakeinhibitoruseandmortalityinepilepsy:findingsfromacontemporarylinkedelectronichealthrecordscohortstudy.InternationalEpilepsyCongress(Barcelona,Spain)September2017(posterpresentation)

11. JosephsonCB,Gonzalez-IzquierdoA,DenaxasS,FitzpatrickN,SajobiT,EngbersJ,PattenS,JetteN,andWiebeS.Serotoninreuptakeinhibitoruseandmortalityinepilepsy:findingsfromacontemporarylinkedelectronichealthrecordscohortstudy.InformaticsforHealth2017,AFarrInstitutescientificconference(Manchester,UK)April2017(platformpresentation)

12. LukmanjiS,SauroK,JosephsonCB,WiebeS,NurseS,andJetteN.ALongitudinalCohort

StudyontheImpactoftheClobazamShortageonPatientswithEpilepsy:APatientPerspective.AnnualCalgaryEpilepsyProgramandtheHotchkissBrainInstituteEpilepsyNeuroteamResearchRetreat(Calgary,Canada)March2017(platformpresentation)

13. JosephsonCB,LowerisonM,VallenrandI,SajobiTT,PattenS,JetteN,WiebeS.Amulti-cohortapproachtoestablishingmajordepressivedisorderasbothanindependentriskfactorandmodifieroftheexpressionofepilepsy.EuropeanEpilepsyCongress(Prague,CzechRepublic)September2016(platformpresentation)

14. Josephson CB, Engbers JDT, Patten S, Lowerison M, Sajobi TT, Jette N, Wiebe S.Psychologicaladverseeffectsof levetiracetamcomparedtosevenothercommonanti-

epilepticdrugsinadultswithepilepsyingeneralpractice;anupdatedanalysis.EuropeanEpilepsyCongress(Prague,CzechRepublic)September2016(posterpresentation)

15. Fishman J, Cohen G, Josephson CB, CollierM, Bharatham S, Zhang Y,Wild I. Patientemotionsandperceptionsofantiepilepticdrugchangesandtitrationduringtreatmentforepilepsy.AmericanAcademyofNeurology (Vancouver,Canada)April 2016 (posterpresentation)

16. Ewert K, Engbers J, Sajobi T, Josephson CB, Jetté N,Wiebe S. Predictingmortality in

epilepsy in general practice. American Epilepsy Society Meeting (Philadelphia, USA)December2015(posterpresentation)

17. LowerisonMW,EngbersJ,SajobiT,JosephsonCB,JettéN,WiebeS.ImpactofexposuretoneurologicalspecialistcareonmortalityinepilepsyinaCanadianprovincepopulation.American Epilepsy Society Meeting (Philadelphia, USA) December 2015 (posterpresentation)

18. Engbers,J,JosephsonCB,LunneyM,LowerisonM,PattenS,JettéN,WiebeS.Adverse

psychological effects of Levetiracetam in adults with epilepsy in general practice.American Epilepsy Society Meeting (Philadelphia, USA) December 2015 (posterpresentation)

19. LunneyM, Sauro, K, AtkinsonM, Josephson CB, Girgis F, Singh S, Patten SB, JettéN,

Hader W,Wiebe S. Identification of themes relevant to patients’ evaluation of theirsatisfactionwith epilepsy surgery through focus group discussions. American EpilepsySocietyMeeting(Philadelphia,USA)December2015(posterpresentation)

20. Josephson CB, Sauro, K., Clement, F.,Wiebe, S. and Jette N.Medical versus invasive

therapy in AVM-related epilepsy: systematic review and meta-analysis. InternationalEpilepsyCongress(Istanbul,Turkey)September2015(posterpresentation)

21. JosephsonCB,EngbersJ,JetteN,Agha-KhaniY,FedericoP,HansonA,MurphyW,Pillay

N, andWiebe S. Epilepsy in the elderly: a distinct entity? American Epilepsy SocietyAnnualMeeting(Seattle,USA)December2014(posterpresentation)

22. JosephsonCB,EngbersJ,JetteN,Agha-KhaniY,FedericoP,HansonA,MurphyW,PillayN, andWiebe S. The clinical and psychosocial impact of the postictal state. AmericanEpilepsySocietyAnnualMeeting(Seattle,USA)December2014(posterpresentation)

23. Josephson CB, and Pillay N. A case of intractable focal epilepsy. Western EpilepsyConference(Banff,Canada)February2014(platformpresentation)

24. Josephson CB, and Jette N. A case of status epilepticus in the context of AngelmanSyndrome.Mary Ann Lee Annual Meeting (Calgary, Canada) October 2013 (platformpresentation)

25. JosephsonCB,andWiebe.Aselectiveapproachtoastandardproblem?Comparisonofselective amygdalohippocampectomy and standard anterior temporal lobe resection.InternationalLeagueAgainstEpilepsyMeeting(Montreal,Canada)June2013(platformpresentation)

26. JosephsonCB,DykemanJ,FiestKM,LiuX,SadlerRM,JetteN,andWiebeS.Comparisonofstandardandselective temporal lobesurgery:systematic reviewandmeta-analysis.American Epilepsy Society AnnualMeeting (San Diego, USA), December 2012 (posterpresentation)

27. Josephson CB, and Al-Shahi Salman R. The 30-day complication rate following brainarteriovenous malformation/aneurysm embolisation: prospective population-basedstudy. 1st Annual World AVM Congress (Edinburgh, UK) September 2012 (platformpresentation)

28. Josephson CB, Al-Shahi Salman R, Hall JM, Horne MA, Moultrie F, Bhattacharya JJ,CounsellCE,MurrayGD,PapanastassiouV,RitchieV,RobertsRC,SellarRJ,WarlowCP.Untreated clinical course of cerebral cavernous malformations: a prospective,population-based cohort study.AtlanticNeurosciencesMeeting (Halifax, Canada)May2012(platformpresentation)

29. Josephson CB, Gubitz GG, and Philips SJ. A case of neurovascular syphilis. CanadianStrokeCourse(Toronto,Canada)February2012(platformpresentation)

30. Josephson CB, Bhattacharya JJ, Counsell CE, Papanastassiou V, Ritchie V, Roberts RC,SellarR,WarlowCP,andAl-ShahiSalmanR. Seizureoutcomesafter interventionalorconservative management of brain arteriovenous malformations: prospective,populationbasedcohort study.AmericanEpilepsySocietyAnnualMeeting (Baltimore,USA)December2011(posterpresentation)

31. JosephsonCB,LeachJP,DuncanR,RobertsRC,CounsellCE,andAl-ShahiSalmanR.Theriskofepilepticseizureafterthediagnosisofacavernousorarteriovenousmalformation.

Dalhousie University Faculty of Medicine Research Day (Halifax, Canada) May 2011(platformpresentation)

32. JosephsonCB,LeachJP,DuncanR,RobertsRC,CounsellCE,andAl-ShahiSalmanR.Theriskofepilepticseizureafterthediagnosisofacavernousorarteriovenousmalformation.Dalhousie University Department of Medicine Research Day (Halifax, Canada) March2011(platformpresentation)

33. JosephsonCB,LeachJP,DuncanR,RobertsRC,CounsellCE,andAl-ShahiSalmanR.Therisk of epileptic seizure after the diagnosis of a cavernousmalformation of the brain:prospective,population-basedstudy.AngiomaAlliance6thAnnualPathobiologyofCCMScientificWorkshop(Washington,USA)November2010(platformpresentation)

34. Josephson CB, Frantzias J, and Al-Shahi Salman R. An audit of the management ofepilepsyaffectingadultswithacavernousorarteriovenousmalformationofthebrain.AnnualScottishNeurosciencesCouncilandtheNeurologicalAllianceofScotlandMeeting(Edinburgh,UK)September2010(posterpresentation)

35. Josephson CB, Leach JP, Duncan R, Roberts RC, Counsell CE, and Al-Shahi Salman R.Seizure risk from cavernous or arteriovenous malformations: prospective population-basedstudy.RoyalCollegeofPhysiciansandSurgeons (London) InternationalAdvisorsMeeting(London,UK)June2010(posterpresentation)

36. Josephson CB, Leach JP, Duncan R, Roberts RC, Counsell CE, and Al-Shahi Salman R.Seizure risk from cavernous or arteriovenous malformations: prospective population-based study. European Stroke Conference (Barcelona, Spain) May 2010 (platformpresentation)

37. Josephson CB, Al-Azri S, Smyth DJ, Haase D, and Johnston BL. Mycobacterium bovisvertebral osteomyelitis, epidural abscess, andpossible cerebral tuberculoma followingintravesical BCG therapy. CanadianNeurological Sciences FederationMeeting (Halifax,Canada)June2009(posterpresentation)

38. Josephson CB, Grant I, and Benstead T. Opsoclonus-myoclonus with multipleparaneoplastic syndromes and VGCC antibodies. Canadian Neurological SciencesFederationMeeting(Halifax,Canada)June2009(posterpresentation)

39. JosephsonCB,andWeaverD.Consciousnessandtheroleofgamma-wavesynchronicityinsensorybinding.JulianJaynesConferenceonConsciousness(Charlottetown,Canada)August2008(platformpresentation)

40. Josephson CB, Rahey S, and Sadler RM. Neurocardiogenic syncope: frequency and

consequencesofitsmisdiagnosisofepilepsy.CanadianCongressofNeurologicalSciences(Montreal,Canada)June2006(platformpresentation)

41. JosephsonCB,GubitzGG,andPhillipsSJ.Pre-strokefunctionalstatusinfluencesoutcome

inpatientsclassifiedaccordingtotheOCSPsubtype.CanadianCongressofNeurologicalSciences(Montreal,Canada)June2006(platformpresentation)

42. JosephsonCB,HowlettJG,JacksonSD,FinleyJ,andKellsCM.SystemicRightVentricular

Dysfunction Post Atrial Switch for Isolated D-Transposition of the Great Arteries: TheImpactofBeta-Blockade.CanadianCardiovascularCongress (Calgary,Canada)October2004(posterpresentation)

43. Josephson CB, and Orlowski J. Determination of Sites in the Na(+)/H(+) Exchanger

Isoform 1 (NHE1) Involved in Ion Translocation. NHE Congress on Advances in Na-HExchange Research: From Molecular Regulation to Therapeutic Advances (A satellitesymposiumofIUPHAR2002)(London,Canada)July2002(posterpresentation)