Coeliac Disease
4
Coeliac Disease 1% UK population 3% Pts presenting with “IBS” symptoms Minimal/atypical symps 2:1 female – male Smoking protective
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Coeliac Disease. 1% UK population 3% Pts presenting with “IBS” symptoms Minimal/atypical symps 2:1 female – male Smoking protective. Coeliac Serology. Antigliadin Ab Assays – obsolete IgA Endomyseal Ab (EMA) IgA TTG Ab – beware IgA deficiency Highly sensitive & specific - PowerPoint PPT Presentation
Transcript of Coeliac Disease
Coeliac Disease
1% UK population 3% Pts presenting with “IBS” symptoms Minimal/atypical symps 2:1 female – male Smoking protective
Coeliac Serology
Antigliadin Ab Assays – obsolete IgA Endomyseal Ab (EMA) IgA TTG Ab – beware IgA deficiency
Highly sensitive & specific
Good screening test for Coeliac Disease
Diagnosis
Serology +/Histology+Coeliac Disease
Serology +/Histology - Review/repeat bx 1yr
Serology-/Histology+ Consider other causes enteritis.If none treat as Coeliac
Serology-/Histology- Diagnosis excluded
Management
GFD – most can eat oats Screen for and manage osteoporosis Persistent symps – check diet, think of other
things Refractory Coeliac – low-grade lymphoma
