Code of business conduct - Idorsia

The main provisions of the code are:• EmployeesofIdorsiaanditsworldwideaffiliatesareresponsible

for always demonstrating honesty, integrity, and respect in their workactivities,obeyingapplicablelawsandregulations,andadheringtoIdorsiapoliciesandprocedures,includingthisCodeofBusinessConduct.

• Supervisorsareaccountableforcomplianceandbusinessconductinthegrouptheymanage.

• Departmentheadsareaccountableforcomplianceandbusinessconductintheirfunctionaloroperationalarea.

• Idorsiaiscommittedtoaworkenvironmentthatencourageshonestdiscussionofissuesandconcernsaboutlegalcompliance,Companypolicy,andbusinessconduct.

“The Code”Idorsia’sCodeofBusinessConduct(“theCode”)establishescorporatestandardsofbehaviorforallIdorsiaemployees.BymaintainingthestandardsofconductdescribedinthisCode,youenableIdorsiatofulfillitscommitmenttothehighestintegrityinbusinessconduct.

Codeofbusinessconduct

The Code

Legal compliance & ethical practices

The workplace

Data & information policies

Clinical&scientificintegrity

Animal welfare

Personal responsibility

Reporting, investigation, & enforcement

How should i use the code?While all Idorsia employees are expected to exercisegoodjudgment,itisnotalwayseasytodeterminewhatis“right”dependinguponthecircumstances.Idorsia’sCodeofBusinessConductisintended to help employees arrive at therightdecision,providingguidanceinsituationsthatmayposequestionsorrequiredifficultjudgments.

• Employeeswholearnoforsuspectalegal,ethical,orpolicyviolationmustraiseitwiththeirsupervisor,ortheirlocalcompliancechampion,ortheCorporateComplianceOffice,orthroughtheGlobalComplianceHelplineat0800110007(forSwitzerland),+41588440106foroutsideSwitzerland,[email protected].

• Idorsiadoesnotpermitmeasuresagainstanyonewho,ingoodfaith,raisesissues,concerns,orallegationsofcomplianceviolationsorunethicalconduct.

• Idorsiawillinvestigateallallegationsofmisconduct,includingviolationsofthisCodeand,whereappropriate,takedisciplinaryandcorrectiveaction,uptoandincludingterminationofemployment.

Whilecoveringawiderangeofbusinesspracticesandprocedures,thisCodecannotanddoesnotcovereveryissuethatmayarise,oreverysituationwheredecisionsmustbemade;rather,itsetsforthkeyguidingprinciplesthatrepresentCompanypoliciesandestablishedconditionsforcontinuedemployment.

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Acting with honesty, integrity, and respect isthefoundationuponwhichthisCodeisbuiltandhowIdorsiaconductsbusiness.Inadditiontothisguidingprinciple,obeyinglawsandregulations,bothinletterandinspirit,iscriticaltooursuccess.WhileIdorsiaemployees are not expected to know the detailsofeverylaworregulation,itisimportant that employees are aware of the corerequirementsestablishedinthisCodeand know when to seek advice from their supervisorortheCorporateComplianceOffice. Idorsia strives to provide fair and competitivewagestoouremployeesbasedonperformanceandethicalconductandtoprotectouremployeesfromunsafeorimproperworkingconditions.

Idorsiaisalsocommittedtoqualityinthemanufacturing,packaging,andtestingofitsproducts.Toensurepatientsafety,itstrivestomeetorexceedapplicableregulatoryauthorityrequirementsforcurrentGoodManufacturing,ClinicalandLaboratoryPractices(cGXPs).

Idorsiaisrequiredtocompileandmaintainnumerousrecordsandtofilereportsandapplicationswithvariousgovernmentagencies.Virtuallyalloftheseagenciesoperateunderlawswhichmakeitacrime-punishablebyfinesand/orimprisonment-toknowinglysubmitfalseorincompleteinformation,tofailtosubmitrequiredinformation,ortofailtosubmitinformationwithinarequiredtimeperiod.CarelessnessalonecanconstituteanoffenseinsomeinstancesandcancallintoquestionIdorsia’scompetencyandgoodfaith.

Accordingly,Idorsiarequiresthatallemployees who prepare information, records,orsubmissionsforgovernmentalagencies, or who otherwise deal with suchagencies,dosodiligently,accurately,completely,andwithabsoluteintegrity.

ToensureIdorsiaemployeesarepreparedtoperformtheirdutieseffectivelyandincompliancewithourqualityrequirements,theCompanyprovidesappropriateinstructionandtraining.

Eachdepartmentheadisresponsibleforensuringthatemployeeswithintheirgroupcompleteallrequiredtraining.Employeesareexpectedtocompleteprescribedtraining and acknowledge, in writing, that theyunderstandandwillcomplywithrelevantlaws,rulesandregulations,aswellasCompanypoliciesandprocedures.

Laws and regulations with which idorsia must comply include, among others, those that address:• The research, development, pharmacovigilance,manufacturing,marketing,promotion,anddistributionofpharmaceuticalproducts

•Laborandemploymentlaws•Securitieslaws•Anti-competitive(anti-trust)laws• Privacy laws•CorporateGovernancelawsrelatingtodutiesowedbycorporatedirectorsandofficers

Compliancewithlaws&regulations

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Interactionswithvendors,customers,competitors,collaborators,healthcareprofessionals(HCPs),patients,andgovernmentofficialsmustalwaysbelegal,transparent,andethical.Offeringoracceptinganinducement(financialorotherwise)inexchangeforthepurchaseofand/orrecommendationtopurchaseaproductorserviceisinappropriateandprohibited.

Gifts and entertainmentNon-Governmental, Non-HCP Business AssociatesWhileproviding,hosting,oracceptingabusinesscourtesy,suchasamodestmeal,giftand/orentertainment,maybeacceptableundercertaincircumstances,thebusinesscourtesymustbereasonableinnature,permissibleunderapplicablelawsandregulations,andcompatiblewithindustrystandardsandlocalcustoms.Toavoideventheappearanceofaconflictofinterest,employeesmustexercisecaution,honesty,andgoodjudgment.Inuncertaincircumstances,orifthereisanydoubt,thesituationmustbepresentedtoasupervisor,whohastheultimateresponsibilityandauthoritytoapprovetheofferingoracceptanceofabusinesscourtesy.

Idorsiaemployeesarestrictlyprohibitedfromrequestingbusinesscourtesiesofanykind.Ifrefusalofagiftthatexceedsnormalbusinesscourtesywouldoffendthegiver,thegiftshouldbeacceptedandthenforwardedtotheCorporateComplianceOfficeforappropriatehandling.

Businesspractices

Examples of prohibited “inducements” to secure business may include:• Gifts,entertainment,orhospitalitythatis

excessive or lavish• Donationstothirdpartiesattherequest

or direction of another party• Paying travel expenses or accommodations foranindividualwithoutalegitimatebusinesspurpose

• Accepting or providing a gift, money, cash equivalent,orotheritemofvalue

• Providing free goods or services• Paymentstogovernmentofficialstoinfluencegovernmentalactions

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HCPs, Business AssociatesOfferingbusinesscourtesiestoHCPsisregulatedinmanycountriesbylawand/orindustrycodes,whichareconcernedwiththepotentialconflictofinterestcreatedbyindustry’sinfluenceonHCPs.Toaddresstheseconcernsandensureourfocusremainsonpatientcare,Idorsiaiscommittedtoonlyprovidingbusinesscourtesiesconsistentwithlocalcountryrequirements,andforthepurposeoffacilitatingpatientorHCPeducation.

Forthisreason,businesscourtesiesmayneverbeprovidedwiththeintentofinappropriatelyinducinganHCPtoprescribe,purchase,orrecommendanyproducts.

Government OfficialsManycountrieshaveanti-briberylawsregulatingtheofferingofbusinesscourtesiestogovernmentemployeesandrepresentatives(collectively,“governmentofficials”).Idorsiapolicyprohibitsoffering,promising,paying,orgivinganythingofvalue,directlyorindirectly,toagovernmentofficialforthepurposeofundulyinfluencingagovernmentaction.Prohibiteditemsofvaluemayinclude,butarenotlimitedto,cashpayments,meals,personalgifts,travel,andentertainment.

Around the world there are wide-ranging interpretations of “normal business practices”. What is considered a customary business courtesy in one country may be viewed as improper in another. What does that mean for idorsia employees?Idorsiaemployeesmustnotprovideanypaymentorbenefitofanykindorprovideanythingofvaluetogainanimproperbusinessadvantageregardlessofthecountryinwhichtheconducttakesplace.Before making any payment or providing anythingofvalue,seekguidancefromyoursupervisor,yourlocalcompliancechampion,ortheCorporateComplianceOffice.

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Anti-competitive practices and fair dealingIdorsiaiscommittedtoprotectingfreeenterprisethroughcompliancewithapplicableanti-competitionlawsandregulations.ViolationoflawsandregulationsdesignedtoensurecompetitionandfreeenterprisecanhaveseriousconsequencesfortheCompanyandforindividuals.Belowaresomeexamplesofactivitieswithimportant anti-competition implications:

•Agreeingwithcompetitorstofixpricesorothertermsofsale•Boycottingcertainsuppliersorcustomers•Dividingsalesopportunitieswithcompetitorsbyterritoryorproductline

•Agreeingwithdistributorsonmandatoryresalepricing• Price discrimination• Disparaging, misrepresenting, or harassing a competitor

Anti-competitionissuesarecomplexandshouldbereferredtotheGroupGeneralCounsel.Idorsiaseekstooutperformcompetitionfairlyandhonestlythroughsuperiorperformanceandneverthroughdubiousorillegalbusinesspractices.Misappropriatingproprietaryinformation,possessingtradesecretinformationthatwasobtainedwithouttheowner’sconsent,orinducingsuchdisclosuresbypastorpresentemployeesofothercompaniesisprohibited.

International tradeEmployeeswhosejobfunctionsinvolveinternationaltrademustbeknowledgeableofandcompliantwiththeapplicablelegalrequirementsandrestrictions,suchastradeembargoes,boycotts,import/exportrestrictions,localimportationcustomspracticesandrequirements,andothertradeandtaxationlawsandregulations,aswellasrelevantCompanypolicies.Forquestionsrelatingtomattersofinternationaltrade,employeesmustconsulttheirsupervisorortheGroupGeneralCounsel.

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AconflictofinterestexistswheneveranindividualrepresentingIdorsiausestheirpositiontoengageinconductthatcompromises,orappearstocompromise,theirabilitytomakeanimpartialbusinessdecisiontotheultimatebenefitoftheCompany.

Idorsiaemployeesarestrictlyprohibitedfromengaginginanyactivitiesthatmayresultinaconflictofinterest,unlesspreviouslydisclosedtotheirsupervisorandauthorizedbytheCorporateComplianceOffice.

Itisnotpossibletodescribeeverysituationoroccurrencethatcouldleadtoaconflictofinterest.Therefore,employeesmustavoidanycircumstancethatcouldevenleadtotheappearanceofimpropriety.

What are some ways to avoid conflicts of interest?Idorsiaemployeescanavoidconflictsofinterestbyalwaysbasingbusinessdecisionsonnormalbusinessconsiderationssuchasquality,cost,availability,reputation,andotherfactorsbearingdirectlyontheproductorservice.Idorsiaemployeesmustnotusetheirpositiontodirectlyorindirectlybenefitthemselvesorothers(includingbutnotlimitedtorelativesorcloseassociates).

Decisions and actions involving Idorsia and itsbusinessmustalwaysbebaseduponwhatisinthebestinterestsofIdorsia.Ifyouareuncertainwhetheraconflictofinterestmightexist,contactyoursupervisorortheCorporateComplianceOfficebeforemakingadecisionorengaginginanactivity.

Conflictsofinterest

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Somecommonconflictofinterestsituationsmayinclude:

Financial interestsHolding,byanIdorsiaemployeeordirectfamilymember,adirectorindirectfinancialinterestofmorethan5%inavendororcustomer.

EmploymentBeingemployedby,providingconsultingservicesfor,orservingasanofficerordirectorofanothercompany,includingbutnotlimitedtocompetitors,customers,suppliers,orvendorstoIdorsia.

Business and financial transactionsConductingIdorsiabusinesstransactionswith a company that employs a family memberofanIdorsiaemployee.Enteringintopersonalfinancialtransactionswith an employee or representative of a customer,competitor,orvendor.

Corporate opportunitiesUsingnon-publicinformationacquiredasaresultofemploymentwithIdorsia.TakingadvantageofbusinessopportunitiesthatrightfullybelongtoIdorsia.SellingservicesorproductsthatcompetewithIdorsia.

Non-business activitiesParticipatingintradeassociation,non-profit,orothernon-businessactivitiestothedetrimentofperformingIdorsiajobduties.

Personal use of company property and informationUsingordivertingCompanypropertyfornon-businessactivities.Note:Theaboveexamplesareprovidedforillustrationanddonotrepresentacomprehensive listing of all potential conflictofinterestsituations.

The spouse of an idorsia employee has an ownership interest in an advertising company idorsia is considering using. The idorsia employee does not have any decision-making responsibilities as to which vendor is selected. Does this present a conflict of interest?No.Thisisapotentialconflictofinterest.Importantly,anyactualorpotentialconflictofinterestoreventheappearanceofaconflictofinterestcoulddamageanemployee’sreputationorthatoftheCompany.TherelationshipmustimmediatelybedisclosedtoyoursupervisorortotheCorporateComplianceOfficeforadvice.

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Itisrecognizedthatasamemberofahighlyregulatedandpubliclyvisibleindustry,certainpoliticalinitiativesmayaffectIdorsiabusiness.Idorsia’spoliticalactivitieswilloccuronlythroughparticipationinandmembershipofindustryassociations(e.g.,Interpharma,PhRMA).TheChiefExecutiveOfficermustapproveconsultationandhiringofpoliticallobbyistsaswellasactiveorpassive participation in any associations, parties, or other interest groups.

Directsupport(financialorotherwise)ofpoliticalpartiesorindividualcandidatesforpublicofficebyIdorsiaisprohibited.Idorsia employees, in their company capacity, cannot make any loan, donation,contribution,orpaymenttoapoliticalparty,candidate,orpoliticalactioncommittee,fororonbehalfoftheCompany,oranyprojectordevelopmentinwhichtheCompanyisengaged,norshalltheycausetheCompanytoreimburseanyindividualwhoprovidessuchsupport.(NothingcontainedinthisPolicyshallprohibitIdorsiaemployeesfromtakinganyoftheaboveactionsasaprivatecitizen,inhisorhername,providedthattheactionisexclusivelyontheirown accord and is not an indirect means of accomplishing one of the prohibitedactions.)

Forquestionsrelatingtopoliticalcontributionsandactivities,consultwithyoursupervisor,yourlocalcompliancechampion,ortheCorporateComplianceOffice.

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Interactions with othersIdorsiaisfirmlycommittedtoprovidingequalopportunityandapositiveworkingenvironmentinallaspectsofemployment.Idorsiaemployeesmusttreateachotherandourthirdpartystakeholderswithrespectatalltimes.

Discriminationbasedonrace,color,religion,nationalorigin,sexualorientation,gender,age,disability,oranyotherlegallyprohibitedbasis,isprohibited.Thisappliestoallemploymentpractices,includingrecruiting,hiring, pay, performance reviews, training and development, promotions, and other termsandconditionsofemployment.

Similarly, Idorsia does not permit any form of harassment.Thisincludesanyabusiveconduct,includingverbal,non-verbal,orphysicalconductthat demeans or shows hostility toward an individual.

Policy against retaliationRetaliationorothermeansofcountermeasuresareprohibitedagainstanyemployee who has made a complaint in

The work environment

What behaviors might be considered harassment?Behaviorthatmightbeconsideredharassment may take many forms and canincludewords,gestures,oracts.Examplesincludejokesrelatedtorace,religion, ethnic origin, or other personal characteristics,teasingthatcausessomeonetofeelhumiliated,bullying,displaysofinappropriatematerial,unwelcomeflirtingorsexualadvances,andthreatsofviolence.

Beawarethatbehaviorthatis“acceptable”inonecountrymaynotbeacceptableelsewhere.

goodfaithaboutdiscrimination,harassment,sexualharassment,wrongdoingandviolationsoflaw,orCompanypoliciesorprocedurestoappropriateCompanymanagers, or who has cooperated in the investigationofsuchacomplaint.

RetaliationincludesanyemploymentdecisionorotherconductmadewiththeintenttopunishanemployeeforsubmittingacomplaintorassistinginaCompanyinvestigation, as well as any decision or conductthatmighthavediscouragedanemployeefromsubmittingacomplaintorcooperatinginaninvestigation.

Health, safety, and the environmentIdorsiarecognizesthatexcellenceinhealthandsafety(“H&S”)performanceisintegraltoanefficientandsuccessfulbusiness.IdorsiawillconstantlypursuehighstandardsofH&Sperformanceinallitsactivities.

AllemployeesmustcomplywiththeCompany’senvironmental,health,andsafetypoliciesandprocedures,aswellaslocallawsandregulations.Employeesmustalsoattendrequiredtrainingandperform

theirjobsinamannerthatpromotesasafeand healthy workplace while also preserving andprotectingtheenvironment.

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AllIdorsiafacilitiesandequipmentareIdorsiaproperty.EmployeesareresponsiblefortheappropriateuseofIdorsiafacilities,equipment,andservices.Anysuspectedincidentoftheftorfraudmustbereportedimmediatelyforinvestigation.

Employees are not permitted to access anotheremployee’sofficeorcomputerunlesspriorpermissionisreceivedfromthatemployeeorfromasupervisorininstanceswheresuchactionisnecessarytoconductCompanybusiness.ItisagainstCompanypolicytouseordivertanyCompanyproperty,includingservicesofotheremployeesandCompanyinformation,forpersonaladvantageorbenefitorforuseinnon-Idorsiabusinessactivitiesornon-businessactivitiesunrelatedtotheCompany.

Idorsiacomputers,communicationsdevices/equipment,andnetworksmayonlybeusedinaccordancewithCompanypolicyandmayneverbeusedtoaccess,receive, or transmit material that is illegal orinappropriate.IfsendingproprietaryorconfidentialinformationtopersonsoutsideoftheCompany’semailsystemorif receiving information from persons that aretransmittingsuchinformationviaanon-company email or data transfer system, theCompany’sITsafetyprotocolsandprecautionsmustbeobserved.

BusinesstravelmusthavealegitimatebusinessrationaleandbeconductedinsuchamannerastooptimizethebenefitofthetriptotheCompany(e.g.,maximizeuseofemployeetimespentworkinguponCompanybusinesswhilealsousingCompanyresourcesefficiently).

Idorsia property & resources

Equipmentandelectroniccommunications

Travel

Protecting company property and resources:•HandleCompanyassetsandequipmentcarefullytominimizelossanddamage

•UseCompanyassetsforlegitimatebusinesspurposesonly

•SecureCompanyequipmentandinformationsuchaslaptopsorworkfileswhen traveling or at other times when theyareoutsidetheoffice

•FollowCompanypoliciesandinstructionsregardinguserIDsandpasswords

•NotifytheGlobalInformationTechnology(IT)departmentandlinemanagementimmediately in the event of loss or theft of equipment

•DonotintroducesoftwareontoCompany-providedequipmentwithouttheadvanceapprovaloftheIdorsiaGlobalITdepartment

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Data and information policies

Companyrecords,suchaslaboratorynotebooks,productinformation,financialinformation,andgovernmentfilings,mustbeanaccurateandverifiablerecordofallactivitiesandtransactions.Alldatamustberecordedandmaintainedaccordingto Idorsia record retention policies and procedures.

TheCompany’sprocessesshallbedesignedtoensurereasonableassuranceofeffectiveandefficientoperations,compliancewithlawsandregulations,andthesafeguardingofassetsandreliablefinancialinformation(Sarbanes-OxleyActof2002).Idorsiaemployeesentrustedwithcontrolovertheseassetsandfinancialinformation,shall,throughtheuseandmaintenance of controls, implement and upholdanenvironmentinlinewithIdorsia’scomplianceFramework.Recordingfinancialtransactions follows generally accepted accountingprinciplesintheUnitedStates(USGAAP)andapplicablelocallaw.Financialinformationshallbepresentedfairly,inallmaterialrespects,reflectingthefinancialpositionoftheCompany.Maintainingundisclosedorunrecordedfundsorassets

Record keeping

andliabilitiesestablishedforanypurposeisprohibited.Financialinformationshallbereadilyunderstandablebyusersandrelevant to the economic decision-making needsofusersinallmaterialrespects.Theinformationfiledwith,orsubmittedto,anyregulatorybody,aswellassharedthroughinternalandexternalcommunicationchannels,hastobereliableintermsofcompleteandfairpresentation.

The manner in which information is recorded reflectsontheCompany’sscientificandbusinessintegrity,andallemployeesareresponsibleforadheringtothehigheststandardsoftheirprofession.Reportsandinterpretationofdataandresults(includingfinancialresults)mustbedoneingoodfaithandinsuchamannerastopreventmisleadingthereader,ordisguisingormisrepresentinganyaspectofatransaction.FalsificationofrecordsormisrepresentationoffactsisprohibitedbytheCompany.

Businessrecordsandcommunicationsoftenbecomepublicandthereforethecontentofsuchrecordsandcommunicationmustbeprofessional,precise,andaccurate,and

may not contain exaggeration, derogatory remarks,guesswork,orinappropriatecharacterizationsofpeopleandcompanies.Thisappliesequallytoelectroniccommunications(suchasemail),internalmemos,andformalreports.

Companyrecordsmustbemaintained,stored and, when appropriate, destroyed inaccordancewiththeCompany’srecordretentionpoliciesandSOPs,andincompliancewithapplicablelawsandregulations(e.g.,drugregulatory,environmental, tax, employment, and trade regulations). Undercertaincircumstances,suchaslitigationorgovernmentalagencyrequests,theCompanymayberequiredtopreservedocumentsandinformationbeyondtheirnormalretentionperiod.

Tounderstandwhichrecordsmustbepreserved,orifaquestionarisesastotheinterpretation of a records and information retentionpolicy,theGroupGeneralCounselshouldbeconsulted.

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Intellectual propertyProtectingIdorsia’sintellectualpropertyis essential to maintaining a competitive advantage.Idorsiaemployeesareexpectedtoestablish,support,maintain,anddefendtheCompany’sintellectualproperty(includingbutnotlimitedtopatents,patentapplications, trade secrets, trade names, trademarks,servicemarks,andcopyrights)ina manner that protects the highly sensitive natureoftheinformationanditscommercialvaluetoIdorsia.

ConfidentialityConfidentialinformationincludesinformationaboutIdorsiaoperations,performance,technology,products,oremployeesthathasnotbeenpubliclydisclosedbyanauthorizedspokespersonoftheCompanyorisnotavailablefrompublicsources.Protectingconfidentialinformationis critical to Idorsia’s competitive edge and is everyemployee’sresponsibility.

Information management

Types of confidential information include:•Researchandscientificdata•Clinicalstudyinformation• Technical designs and processes•Manufacturingdesignsandprocesses• Financial records and data•Marketingandbusinessplans•Unpublishedpatentapplications•Informationthatwouldenablea

competitor to gain a competitive advantage

•InformationthatmayinfluenceIdorsia’ssharevalue

Confidential information that belongs to third partiesProviding Idorsia employees with informationaboutothercompaniesisacceptableonlywhentheinformationisobtainedlawfully(e.g.,throughthepublicdomain).Idorsiaemployeesarenottouse

ordiscloseanothercompany’sconfidentialinformationunlessitwaslegallyobtainedbyIdorsia.ConfidentialinformationrightfullyprovidedtoIdorsiamustbeprotectedandmaynotbeusedordisclosedbyanIdorsia employee to any other party except accordingtothetermsunderwhichitwasprovided.

Idorsiaemployeeswhoareofferedorcomeintopossessionofinformationbelongingtoanothercompanyoraboutanothercompany,andwhoareunsureofitsstatus,orbelieveitmaybeconfidential,shouldconsulttheGroupGeneralCounsel.

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PrivacyIdorsia is committed to protecting the privacy and integrity of personalinformationinallbusinessactivities.Insofarasitislegallypermissible,theCompanymaycollectpersonalinformation;however,itwillonlycollectsuchinformationforlegitimatebusinesspurposesandretainitonlyaslongasisnecessaryorrequiredbylaw.Inaddition,Idorsiatakesprecautionstosafeguardthesecurityof personal information when it is collected, processed, stored, andtransferred,andwillprovidenoticeandobtainconsentpriortoobtainingpersonalinformation,consistentwithapplicablelawsandregulations.

What is personal information?Personalinformationisanyinformationthatcanbeused,aloneorincombinationwithotherinformation,toidentifyaspecificindividual.Itincludessuchinformationasanindividual’sname,birthdate,gender,homeandbusinessaddresses,socialsecuritynumber,identitycard/passportnumbers,driver’slicensenumber,financialaccountandcreditcardnumber,picture,relatives,telephonenumber,emailaddress,andotherdocumentorelectronicidentifiers.

Insider tradingAllnon-publicinformationabouttheCompany(oranothercompany)mustbeconsideredconfidentialinformation.Confidentialinformationthatcouldaffectthepriceofastock(Idorsia’soranothercompany’s)orcouldbeconsideredimportantbyinvestorstradinginastockiscommonlycalled“insideinformation”.Theuseof“insideinformation”forpersonalfinancialbenefitorto“tip”otherswhomightmakeaninvestmentdecisiononthebasisofthisinformationisillegal;doingsocanresultinfinesandcriminalprosecutionbothforthepersonwhotradesandforthepersonwhodivulgestheinformation.

“Inside information” is material, non-public information that investors would consider relevant to making an investment decision.Examplesinclude:•Ongoingnegotiationsofamerger,acquisition,licensing,orsimilar

transaction•Approvalofnewproducts•Entryintosignificantnewcontracts• Sales of assets•Changesinmanagement• Earnings statements or forecasts

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A joint venture partner with whom an idorsia employee is working disclosed that they are on the verge of a major scientific breakthrough. Can the idorsia employee purchase stock in our joint venture partner?No.anIdorsiaemployeecannotpurchasethisstockuntilthefirstbusinessdayaftertheinformationisknowntothepublic.Justasimportantly,theIdorsiaemployeecannot provide this information to any other person(includingbutnotlimitedtohis/herspouse,children,relatives,friends,orcloseassociates)whomightdirectlyorindirectlybenefitpersonallyfromthisconfidentialinformation.

There are very strict laws regarding the useofnon-publicinformationaboutpubliccompaniesthatincludebothcivilandcriminalpenalties.Whenindoubt,donottakeanyactionuntilyouhavediscussedthematterwithamemberoftheIdorsiaLegalDepartment.

To avoid even the appearance of trading on inside information, certain Idorsia employees arerestrictedtospecifictimesinwhichtheycantradeinIdorsiastock.EmployeeswhobelievetheymaybesubjecttothesetradingperiodsorhavequestionsaboutaspecificsituationshouldconsultwiththeGroupGeneralCounselbeforetrading.

RelatedIdorsiaPolicies:POL-000026:InformationTech-nology(IT)AcceptableUse,POL-000071:ProtectionofPersonalData,POL-000048:GlobalCorporatePolicyandProcedureonInsiderTrading

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Clinicalandscientificintegrity

ResearchintegrityisfundamentaltothescientificprocessandtoIdorsia’sabilitytobringnovelproductstomarket.

Idorsia employees are expected to protect the integrity of the research and developmentprocessbyensuringthatallresearch,includingbutnotlimitedtonon-clinical and clinical development, isconductedaccordingtoallapplicablelawsandregulationsandtothegenerallyacceptedstandardsofthescientificcommunity.

Scientificmisconductisprohibited.Examplesofscientificmisconductincludebutarenotlimitedtofabrication,falsification,orplagiarisminproposing,conducting,orreportingresearch.Scientificmisconductdisregardstheintellectualcontributionsandproperty of others, impedes the progress of research,andcorruptsthescientificrecord.

Idorsia is committed to the appropriate useofitsproductsandrecognizestheimportanceofprovidingHealthcareProfessionals(HCPs)withthecriticalinformationthattheyneedtomakefullyinformedprescribingdecisions.

ForthepurposesofthisCode,anHCPisany person or entity that interacts directly with patients and has a role in the diagnosis or treatment of the patient, or is licensed andpermittedbylawtoprescribedrugsformedicaluse,orisinapositiontoarrangefororrecommendthepurchaseorprescriptionorformularyplacementofanyCompanyproduct.

InteractionsandcommunicationsundertakenonbehalfofIdorsiamustbefocusedoninformingHCPsabouttheCompany’sproducts,providingscientificandeducationalinformation,andsupportingmedicaleducation.SinceIdorsiaprovidesinformationthroughvariouschannels,itis

critical that promotional interactions and communicationsareinfullconformitywithapplicableapprovedproductlabelingandmeet the highest professional, marketing, andpromotionalstandards.

All promotional activities and interactions withHCPsmustbeconductedinamannerthatisfairlybalanced,scientificallyrigorous,andcompliantwithapplicablelawsandregulations.ThemarketingandpromotionofproductsforanunapproveduseisillegalandisprohibitedbytheCompany.Furthermore,itisCompanypolicytocomplywithallapplicablelawsandregulationsprohibitingtheofferingorgivingofkickbacks,bribes,orotherimproperinducementstoHCPs.AllrepresentativeswhoareemployedbyoractonbehalfofIdorsiaandwhovisitHCPsmustreceivetrainingaboutapplicablelaws,regulations,industrycodesandCompanypolicies governing appropriate interactions withHCPs.

ScientificintegrityInteractions with healthcare professionals & promotional activities

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Patientsafety,throughtheoptimalperformanceandqualityofproducts,isfundamentaltoourCompany’smission.Idorsiatakesseriouslyitscommitmenttoassurethatourproductshaveandmaintainanacceptablerisk-to-benefitprofilewhenusedinaccordancewiththeproductlabelingandgoodmedicalpractice.TheCompanyperformsextensiveandrobustnon-clinicaland clinical testing to identify the safety andtolerabilityprofileofproductsand,onceapprovedforuse,theproductsarecontinuouslymonitoredthroughtheuseofpost-marketingsurveillanceandspontaneousreportsfromprescribersandconsumers.ItistheresponsibilityofallIdorsia employees to promptly report any adversedrugexperiencesthattheybecomeawareofthatcouldbeassociatedwithanIdorsiaproducttotheCompany’sGlobalDrugSafetyDepartment.

An adverse drug event/experience is defined as any unfavorable and unintended sign, symptom, or disease associated with the use of the product irrespective of causal relationship.Italsoincludes:•Aproductqualitydefect•Exposureduringpregnancyorlactation•Misuse,abuse,oroverdose•Medicationerrors(e.g.,dispensingerrors,maladministration,etc.)

•Overdose(whetherintentional,accidental,orprescribed)

•Occupationalexposureasaresultofone’s professional or non-professional occupation

•Reportsofsuspectedfalsifiedproducts• Reports on any transmission of an infectiousagentviatheproduct/s

•Drug-drugordrug-foodinteractions• Withdrawal symptoms•Lackofeffectorworseningofapre-

existing condition•Anunintendedbeneficialeffect

Monitoring the safety, performance, &qualityofproducts

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Animal welfare

Wheneverpossible,Idorsiaiscommittedtothedevelopmentanduseofscientificallyvalidated alternative testing methods that donotutilizeanimals.TheCompanyworkswithregulatoryauthoritiestoincreasetherecognition and acceptance of alternative models that will not compromise patient safetyortheeffectivenessofmedicinesunderdevelopment.

Inthosecircumstanceswhenitisnecessarytouseanimalstoconductvitalresearch,Idorsiaacknowledgesitsresponsibilitytoensurethatanimalsincludedinstudiesconductedonitsbehalfaretreatedwithrespectandwithahighlevelofhumaneandethicalconcern.

Treatment of animals

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Personalresponsibility

IdorsiaemployeesmustworktopreventviolationsofthisCode.TheCompanyrecognizesthatinsomeinstancesitmaybedifficulttodeterminethecorrectanswertoaparticularsituation.SinceeverysituationthatwillarisecannotbeanticipatedandaddresseddirectlyinourCodeofBusinessConduct,itisimportanttorememberthatthereareresourcesavailabletoassistemployees.Thefollowingpointsshouldbekept in mind:

•Askyourself:WhatexactlyamIbeingaskedtodo?Doesitseemunethical,illegal, or improper?

Personalresponsibility

•Askfirst,actlater:Ifyouareunsureofwhattodoinagivensituation,discusstheproblemwithyoursupervisor,oramemberoftheHumanResourcesorLegaldepartments,yourlocalcompliancechampion,ortheCorporateComplianceOffice.Thisisthebasicguidanceforallsituations.

•SeekhelpfromotherCompanyresources:Incaseswhereyoufeelitisuncomfortabletodiscussanissuewithyoursupervisor,consultwithamemberoftheHumanResourcesorLegaldepartments,yourlocal compliance champion, or the CorporateComplianceOffice.Ifyouwishtoremainanonymous,usetheCompany’sGlobalComplianceHelplineat0800110007(forSwitzerland),+41588440106foroutsideSwitzerland,[email protected].

•YoumayreportCodeviolationsinconfidenceandwithoutfearofretaliation.Ifyoursituationrequiresthatyouridentitybekeptsecret,youranonymitywillbeprotectedtotheextentthatitisfeasible.TheCompanydoesnotpermitretaliationof any kind against employees for reports ofCodeviolations.

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> Personal responsibility


Reporting, investigation & enforcement

AnyemployeewhoreasonablybelievesthattherehasbeenaviolationofthisCodemustreportitimmediatelytotheirsupervisor,theirlocalcompliancechampion,ortheCorporateComplianceOffice,orthroughtheCompany’sanonymousGlobalComplianceHelpline.

IftheviolationisreportedtotheComplianceOffice,itwillpromptlyinvestigatethematter.Theinvestigationwillbehandleddiscreetlyandtheinformationwillbedisclosedtoothersonlyona“needtoknow”basisand/orasrequiredbylaw.Therewillbeno adverse action taken against employees who, in good faith, report violations of this CodeofBusinessConductorwhoparticipateintheinvestigation.IftheinvestigationleadstotheconclusionthataviolationofthisCodehasoccurred,theCompanywilltakeappropriatecorrectiveaction.

Reporting/investigationprocedures

What types of issues should be reported in accordance with this code of business conduct?Examplesofissuesinclude:•Misconductregardingsalesandmarketing

practices•Fraudulentfinancialreporting• Insider trading•Harassmentordiscrimination•Disclosureofconfidentialinformation•Environment,health,andsafetyissues• Data privacy violations

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> Reporting, investigation, & enforcement

Asanalternativetotheproceduresdefinedabove,anyemployeewhoreasonablybelievesthattherehasbeenaviolationofthisCodecausedbyquestionableaccounting,financialorauditingmatters,disclosurematters,potentialviolationsofsecuritiesorregulatorylaws,orfraudagainst stockholders, has the right to submitaconfidential,anonymouscomplaintdirectlytotheGroupGeneralCounsel/GroupComplianceOfficerofIdorsia.ThecomplaintshouldbemadeinwrittenformorthroughsuchothermethodsasaremadeavailablebytheCompanyforsuchpurposes,suchastheGlobalComplianceHelplineandprovidesufficientinformationsothatareasonableinvestigationcanbeconducted.

Proceduresforsubmittingconfidential,anonymouscomplaintsregardingaccounting,regulatory,&auditingmatters

Who should be contacted to report a compliance concern?Dependingonthenatureoftheconcern,there are several options for reporting a concern,includinglinemanagement,thelocalcompliancechampion,theCorporateComplianceOffice,andtheComplianceHelpline.

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TheGroupGeneralCounseland/orGroupComplianceOfficershalldetermine,ordesignate appropriate persons to determine, appropriateactionstobetakenintheeventofviolationsofourCode.IntheeventofaviolationoftheCodebyamemberoftheBoardofDirectorsoranExecutiveOfficeroftheCompany,however,theBoardofDirectors shall determine the actions to betaken.SuchdisciplinaryactionsshallbereasonablydesignedtodeterwrongdoingandtopromoteaccountabilityforadherencetotheCode.

ShouldtherebeafindingthataDirector,officer,oremployeehasviolatedthisCode,theCompanywillprovidethemwithawritten notice of its determination, as well asthenatureofthedisciplinaryactiontobetaken(e.g.,censurebytheBoard,demotionorre-assignmentoftheindividualinvolved,suspensionwithorwithoutpayorbenefits,orterminationoftheindividual’semployment).

Violationsoftheidorsiacodeofbusinessconduct

In determining what action is appropriate inaparticularcase,theGroupGeneralCounsel,GroupComplianceOfficer,orBoardofDirectorsshalltakeintoaccountallrelevantinformation,includingthenatureand severity of the violation, whether theviolationwasasingleoccurrenceorrepeatedoccurrences,whethertheviolationappearstohavebeenintentionalorinadvertent,whethertheindividualinquestionhadbeenadvisedpriortotheviolationastothepropercourseofaction,andwhetherornottheindividualinquestionhadcommittedotherviolationsinthepast.

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TheCorporateComplianceOfficecoordinatesthebusinessconductandcomplianceprograms,andisaresourcetoassistemployeeswithanswerstoquestionsorinterpretationsoftheIdorsiaCodeofBusinessConductandrelatedissues.Itisalsoaresourceforsupervisorsinmanagingcomplianceissues.TheGroupComplianceOfficer(GCO)isthechairmanoftheCorporateComplianceOfficeandreportsdirectlytoIdorsia’sNominatingandGovernanceCommittee.MembersoftheComplianceOfficeinclude:

Ifanemployeeisuncertainwhomtocontact,anyoftheindividualslistedabovemaybecontactedforassistance.Employeesshouldcontacttheseindividualstoaskquestions,raiseissuesorconcerns,orreportsuspectedviolations;anonymously,ifnecessary.Allegedcomplianceviolationswillbeinvestigated.Allemployeesarerequiredtocooperateinanyinvestigation.Failuretofullycooperatemayresultindisciplinaryaction,uptoandincludingtermination.

CorporatepoliciesreferredtointhispolicyandothergenerallyapplicablepolicieswillbepostedonQuatro,accessibleviatheIdorsiaintranet,orcanbeobtainedbycallingtheCorporateComplianceOffice.

The corporate compliance office

Idorsiarecognizesthehardworkandconstant attention needed to maintain high ethical standards and compliance prioritiesintheworkplace.IndividualemployeecommitmenttothisCodeofBusinessConductwilldemonstrateIdorsia’sdedication to integrity, professionalism, quality,respect,andhonesty.ShouldyouhaveanyquestionsorrequirefurtherclarificationrelativetoanyoftheSectionscontainedwithinourCode,pleasedonothesitatetoseekassistancefromyoursupervisor/manager,yourHumanResourcescontact,theGroupGeneralCounsel,ortheGroupComplianceOfficerofIdorsia.

Name Responsibility Phone E-mail

OliverPeinelt Legal&Compliance +41615581242 [email protected]

OlivierLambert QA/CGMP/GCP/GLP +41615656751 [email protected]

AlexKhatuntsev HumanResources +41615656245 [email protected]

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Idorsiaisanindependentbiopharmaceuticalcompanybasedonscienceandinnovation.Thecompanyisspe-cializedinthediscoveryanddevelopmentofsmallmol-ecules,totransformthehorizonoftherapeuticoptions.ItisheadquarteredinAllschwil/Basel,SwitzerlandandisquotedontheSIXSwissExchange(tickersymbol:IDIA).Alltrademarksarelegallyprotectedbytheirrespectiveowners.

DisclaimerThisfactsheethasthesolepurposetoprovidemembersofthepublicwithgeneralinforma-tionabouttheactivitiesofIdorsia.Theforward-lookingstatementsinthisfactsheetarebasedoncurrentex-pectationsandbeliefofcompanymanagement,whicharesubjecttonumerousrisksanduncertainties.

Idorsia Pharmaceuticals LtdHegenheimermatweg91CH-4123AllschwilSwitzerlandwww.idorsia.com

Financial Performance

Latestupdate: June2017

Copyright©2017Idorsia

Code of business conduct - Idorsia

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