Coagulation Disorder Jeopardy DdxClinicalLab Tests Manageme nt Miscellaneo us.

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Transcript of Coagulation Disorder Jeopardy DdxClinicalLab Tests Manageme nt Miscellaneo us.

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Ddx Clinical Lab TestsManagement

Miscellaneous

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Category 1 - 200

Inc. INR, Norm PTT

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Category 1 - 400

Inc PTT, but no bleeding problems

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Category 1 - 600

Inc INR and Inc PTT

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Inc INR, Inc PTT, Dec platelets

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Norm INR, Norm PTT, Norm platelets, but

bleeding

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Most common bleeding sites in Hemophilia A

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Category 2 - 400

Complications of muscle hematomas

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Bleeding sites in vWD

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Category 2 - 800

Skip a turn :-)

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How to distinguish Hemophila A from

Hemophilia B clinically

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Difference between Hemophilia A and vWD in

lab tests

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INR tests these Factors

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Most important lab test in initiating Ddx in pt with lifelong hx of bleeding

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Most likely cause of Inc INR and PTT

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3 lab tests useful in identifying congenital coagulation disorders

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Management of acute life-threatening bleeds

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Treatment for mild to moderate Hemophilia A

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Category 4 - 600

Management of superficial laceration in

Hemophilia A pt

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Category 4 - 800

Treatment for severe vWD

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Treatment of Hemophilia B

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Timeframe of trauma bleeding expected in

Hemophilia A pts

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Management of head trauma Hemophiliac pt

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Category 5 - 600

Major cause of death for all age groups of Hemophiliac pts

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Category 5 - 800

Skip a turn:-)

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Category 5 - 1000

Complications of repeated replacement

therapy for Hemophiliac pts

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The Case of the Bleeding Patient

Rebecca Burton-MacLeod

August 28, 2003

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Case

• 18mo male presents to ED with large bruise on forehead

• mother states pt fell and hit head on coffee-table 2 days ago

• bruise appeared next day, not going away

• otherwise well

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Case Continued

• To reassure mother nothing is wrong:

• order CBC, INR, PTT

• surprise--Inc PTT, Norm INR, Norm CBC