R E S E A R C H

WELCOME BOOKSpring/Summer

2016

Our Work Clarity Research, LLC, is a leading international scientific research organization that conducts rigorous, large-scale research in healthcare across many therapeutic specialties.

Under the guidance of internationally recognized physicians, research scientists, board-certified healthcare attorneys, and expert statisticians, our institutional review board (IRB)-approved clinical studies are producing reliable, informative results. Our research is well-received by healthcare providers and continues to be recognized by major national and international conferences.

We are committed to strategically growing our Company through constant improvement of our approach, capabilities, and operations, and by identifying opportunities to strengthen our global footprint and reputation.

Welcome!

Chronic Pain

Diabetes

Depression/Mental Health

Pharmacogenetics

GERD

Allergies

Immunotherapy

Chronic Sinusitis

Oncology

Scar & Burn

Our Values Our goal is to conduct scientifically rigorous and valid research that advances innovation in science and ultimately helps healthcare professionals provide improved patient care, leading to improved patient health worldwide.

Whether through improving treatment methodologies or identifying new ones, we aspire to make a global positive impact on patient health and to improve quality of life for patients and their families.

Dermatology

Women’s Health

Rheumatoid Arthritis

Areas of Research We develop and conduct clinical observational research studies around the globe in many key therapeutic areas, including:

We invite you to become a Study Investigator, to assist us as we conduct important research around the globe across multiple specialities.

OpportunityBecome A Study Investigator

For more information, call: 1-800-616-9403.To apply online, visit www.clarityscience.com.

All necessary documentation and training is provided to you and your staff.

Applying is easy.

You may be able to help your valued patients achieve better health.

Our research studies are easily integrated into your practice.

Our Study Investigators are a valuable and integral part of our research.We continually invite a select number of busy, successful practitioners to become Study Investigators and to participate in our IRB-approved, clinical observational studies. As a Study Investigator, you have an opportunity to:

Opportunity

Study Investigator

Evaluate your patients’ use of innovative treatment.

Be a part of groundbreaking, global research that may influence healthcare and ultimately help patients worldwide.

If selected, you are compensated for your time and services in identifying and enrolling patients in the study and for the collection and submission of data during the study period.

How Will Being a Study Investigator Affect My Practice?We understand your time is valuable. That’s why we’ve designed our clinical observational studies to work efficiently as part of your busy practice.

We supply you with all the necessary study documentation, as well as 2-3 days of comprehensive in-office training with a trained Clarity Implementation Specialist.

We offer an efficient and compliant electronic submission of patient surveys, which ensures data accuracy and convenience for you.

We provide a dedicated Account Manager, who is available to you for the duration of the study when you have questions or need assistance.

We provide compensation for your participation and time enrolling patients in the study and collecting and submitting data during the study period.

With the help of our Study Investigators, our studies are producing reliable and informative results. We are proud to be recognized and to present our study data at major national and international conferences.

Conference Presentations & Attendance

TARGET Study (Wound, Scar and Burn)TopicAl Silicone in RestorinG Scars and Burn Tissue – Evaluating Therapy

6th SCAR Club September 7-8, 2015

7th Joint Meeting of the European Tissue Repair Society & the Wound Healing SocietyOctober 21-23, 2015

The Journal of Wound Technology, Special Issue: ScarJanuary 2016

34th Annual Meeting of the North American Burn SocietyJanuary 16-21, 2016

15th Annual American Professional Wound Care Association 2016 National Clinical Conference*March 31-April 2, 2016*Awarded First Place for Best Scientific Presentation/Data

3rd Annual Pain Care for Primary Care ConferenceJuly 28-29, 2016

American Academy of Pain Management’s 27th Annual Clinical MeetingSeptember 22-25, 2016

PAINWeek National ConferenceSeptember 6-10, 2016

International Association for the Study of Pain’s 2016 World Congress on PainSeptember 26-30, 2016

TREAT Study (Allergy)Transdermal Relief: Evaluating Allergy Topicals for Perennial Allergic Rhinitis

2016 American Academy of Allergy, Asthma & Immunology Annual MeetingMarch 4-7, 2016

American College of Allergy, Asthma & Immunology 2016 Annual Scientific MeetingNovember 10-14, 2016

OPERA Study (Pain)Optimizing Patient Experience and Response to Topical Analgesics

4th Annual International Conference on Opioids at Harvard Medical SchoolJune 7-9, 2015

PAINWeek National ConferenceSeptember 8-12, 2015

American Academy of Pain Management’s 26th Annual Clinical MeetingSeptember 17-20, 2015

Pain Society of the Carolinas 2015 Annual MeetingOctober 23-25, 2015

American Academy of Pain Medicine’s 32nd Annual MeetingFebruary 18-21, 2016

American Pain Society’s 35th Annual Scientific MeetingMay 11-14, 2016

8th World Congress of the World Institute of PainMay 20-23, 2016

5th Annual International Conference on Opioids at Harvard Medical SchoolJune 5-7, 2016

Study ResultsOur clinical observational studies are producing reliable and positive results:

OPERA Study (Pain)Optimizing Patient Experience and Response to Topical Analgesics

Interim data from our OPERA study suggests that the topical/transdermal analgesics used by patients in the study may*:

Reduce BPI severity and interference scores for adult patients with neuropathic and musculoskeletal pain

Reduce the number of primary pain complaints for each of arthritis, neuropathy or radiculopathy, myofascial/musculoskeletal pain or spasm, and tendinitis

Reduce the use of oral OTC, anti-inflammatory and opioid analgesics

TARGET Study (Wound, Scar and Burn)TopicAl Silicone in RestorinG Scars and Burn Tissue – Evaluating Therapy

Interim results from our TARGET study suggest that the scar/burn creams used by patients in the study may*:

Reduce scar/burn size (as measured by clinicians and as perceived by patients)

Reduce itching

Reduce daily living interference scores and improve mood

Reduce pain medication use

*Visit www.clarityscience.com/studies-outcomes for interim data.

TARGET Study (Wound, Scar and Burn)TopicAl Silicone in RestorinG Scars and Burn Tissue – Evaluating Therapy

Who can apply to become a Study Investigator?

Any licensed U.S. physician with an active NPI number can apply to become a Study Investigator.

What are my responsibilities as a Study Investigator?

Study Investigators are responsible for identifying and enrolling patients who have been prescribed a treatment that the study protocol is observing and evaluating. Responsibilities also include collecting and submitting study data during the study period.

Who can be enrolled as a study participant?

Inclusion criteria for study participants varies by study. As a Study Investigator, you will be provided with a study protocol, where you can find full details regarding which of your patients are eligible to participate in the study.

What is an institutional review board (IRB)?

An institutional review board (IRB) is a committee that performs ethical review of proposed research. The U.S. Department of Health and Human Services requires a registered IRB to approve research before involvement of human subjects can begin.

Will my participation as a Study Investigator interfere with my day-to-day practice?

We understand your time is valuable, so we’ve designed our studies to be as non-invasive to your practice as possible. We supply all the study documentation you will need, along with personalized training and administrative support throughout the duration of the study period.

FAQs

How long is training?

After becoming a Study Investigator, a Clarity Implementation Specialist will travel to your location to provide in-office training to you and your staff over 2 or 3 days. Training includes: How to conduct the study, review of study documentation, and how to collect and submit study data to Clarity.

How is compensation determined?

Compensation for Study Investigators is determined based on third-party fair market value (FMV). You will be compensated for your time and services in identifying and enrolling patients and collecting and submitting study data during the study period.

What happens if I have questions during the study?

As a Study Investigator, you will be assigned an Account Manager, who will be available to you when you have questions or need assistance during the duration of the study.

How do I apply to become a Study Investigator?

If you are interested in becoming a Study Investigator for one of our current or future studies, please contact us at: 1-800-616-9403. To apply online, please visit us at www.clarityscience.com.

1-800-616-9403 | studies@crcsciences.com | www.clarityscience.com6300 Bridge Point Parkway, Building 3, Suite 200 | Austin, TX 78730

R E S E A R C H