1

C U R R I C U L U M V I T A E P R O F . G I L D A

C I N N E L L A

PERSONAL INFORMATIONS

Name CINNELLA GILDA

Address 257, VIA ABATE GIMMA, 70122 BARI, ITALY

Telephone 0039 0805248216 – 320 4394598

Fax 0039 0805248216

E-mail g.cinnella@unifg.it

Nationality ITALIAN

Date of Birth 22 MARZO 1962

WORKING EXPERIENCE

• Since 2005 ASSOCIATE PROFESSOR OF ANESTHESIA AND INTENSIVE CARE

University of Foggia

Main duties and responsibilities Clinical and experimental research activities and clinical activities at the Department of Anesthesia and Intensive Care

• 1999-2004 ASSISTANT PROFESSOR OF ANESTHESIA AND INTENSIVE CARE

University of Foggia

Main duties and responsibilities Clinical and experimental research activities and clinical activities at the Department of Anesthesia and Intensive Care

• 1999 ASSISTANT PROFESSOR OF ANESTHESIA AND INTENSIVE CARE

University of Bari

Main duties and responsibilities Clinical and experimental research activities and clinical activities at the Department of Anesthesia and Intensive Care

• 1989-1999

Main duties and responsibilities

STAFF ANAESTHESIOLOGIST

Hospital ‘Policlinico’- BARI

Department of Anesthesia and Intensive Care

Staff anaesthesiologist (Obstetrics and Gynecology), 1989-90, Cardiosurgery, 1990-91, e il Intensive Care, 1991-99.

• 1988-1989

Main duties and responsibilities

INTERNE DE SPECIALITE

Université Paris XII- Créteil, France

Service de Réanimation Médicale, Hopital Henri Mondor

Clinical and experimental research activities and clinical activities at the Réanimation Médicale.

EDUCATION

2

• 2000 Certificate in Epidemiological Methodology

University of BARI

Thesis "Effectiveness of the trans-oesophageal echocardiography in the diagnosis of aortic

traumatic injury: meta-analysis of the literature ".

50/50 and honours

• 1994-1998 Residency in Pneumology

University of BARI

Thesis "Comparison between two methods of measure of the airways occlusion pressure (P0.1) during assisted mechanical ventilation in BPCO patients with intrinsic PEEP"

50 /50 and honors

• 1986-1989 Residency in Anesthesiology and Intensive Care

University of BARI

Thesis "Evolution in ' vivo' of the resistance and the diameter of the endotracheal

tubes". 50 /50 and honors

• 1986 STAGE at SERVICE DE NEPHROLOGIE ET D’HEMODIALYSE, HOSPICES CIVILS, UNIVERSITE DE STRASBOURG, FRANCE

• 1986 M.D. Degree

University of BARI

Thesis "Endotoxins in the pathogenesis of the epato-renal syndrome"

110/110 and honors

LANGUAGES.

MOTHERTONGUE ITALIAN

ENGLISH

• Reading excellent

• Writing excellen

• Speaking Excellent

FRENCH

• Reading excellent

• Writing excellent

• Speaking excellent

AWARDS

2015

2014

European Society of Regional Anesthesia & pain Therapy – Best ePoster

competition 34th ESRA Congress. The prize has been awarded for the poster

entitled: Spinal anesthesia: comparison of two different doses of

Levobupivacaine for cesarean delivery. D’Ambrosio A, Beck R, Salatto P,

Del Vecchio P, Zibar L, D’Antini D, Mirabella L, Cinnella G. Reg Anest &

pain Med, 2015; 40(5):S1, e177

European Society of Anesthesiology –Baxter prize, awarded for a clinical,

peer-reviewed publication or a laboratory peer-reviewed publication of

significant relevance on the following area of interest: Improving patient

recovery after general anaesthesia. The prize has been awarded for the paper

entitled: Effects of recruitment maneuver and positive end-expiratory pressure

on respiratory mechanics and transpulmonary pressure during laparoscopic

surgery. Cinnella G, Grasso S, Spadaro S, Rauseo M, Mirabella L, Salatto P,

De Capraris A, Nappi L, Greco P, Dambrosio M.

Anesthesiology. 2013 Jan;118(1):114-22

3

2011

2005

Award from the Società Italiana di terapia del Dolore (FEDEROLORE), VI

National Congress for the communication entitled “Symptoms and sensory

profiling in 11 patients with trigeminal nevralgia”

Award from the Società Italiana di Analgesia, Anestesia, Rianimazione e

Terapia Intensiva (SIAARTI), held at the 59th National Congress of the

SIAARTI, for the communication entitled: “Continuous epidural anaesthesia:

levobupivacaine vs levobupivacaine-sufentanyl. Neuroendocrine response

effects and gene polymorphism for the opioids

ORGANIZATION SKILLS ACADEMIC ACTIVITIES

2015 Italian Government Labor Dept: National Observatory on Disabilities:

working group n. 4 “Students training and school inclusion”

since 2013 Rector Delegate for Special Needs Students

2013 Member of the Ethics Committeee ‘Riuniti’Hospital, Foggia

Since 2012 Programme Director of the School for Nurses, University of Foggia.

2008-2012 Graduate Programme Director of the Master in Nursing, University of Foggia

2007-2010 Director of the Residency School in Anesthesia and Intensive Care University of Foggia

2005-2006 Director of the Residency School in Geriatrics – University of Foggia

2004-2008 Chairman of the Medical School’s Didactic Commission

2002-2006 Rector delegate for the work group CRUI on the 6° FP of European Community.

2000-2010 Coordinator Socrates/Erasmus program – Faculty of Medicine -University of

Foggia 2002-2004 Member of the Academic Senate, University of Foggia

2000-2006 Rector delegate for Scientific research - University of Foggia

1999-2001 Member of the University Administrative Board - University of Foggia

TECNICAL SKILLS PEER REVIEWER ACTIVITIES – REFEREE FOR:

2016 European commission Horizon 2020: PHC 21 – 2016: Scaling up evidence in pblic health.

2015 European commission Horizon 2020: PHC 30 – 2015: Digital representation of heath

data to improve diagnosis and treatment

2013 - 2014 European commission Horizon 2020: PHC 23 – 2014: Developing and comparing new models for

safe and efficient, prevention oriented health and care systems

2013 Czech-Norwegian Research Programme (CZ09) financed from Norway Grants

2013 European Commission 7th FP: HEALTH.2013 INNOVATION, theme: Understanding and

controlling pain.

2012 European Commission 7th FP – eCOST Trans Domain Proposal action

Since 2012 European Food Safety Authority (EFSA)

Since 2012 Agenzia Italiana del Farmaco (AIFA): included in the experts database

2012 Referee for the Italian Government in the VQR (Quality of Research evaluation) activity

2010-12 European Commission 7th FP: HEALTH.2013 theme: Comparative effectiveness research

(CER) in health systems and health services interventions

2008-12 Referee for Joung investigator grants (Futuro in Ricerca) Italian Governement 2008-12 Referee for National research projects (PRIN) Italian Governement.

2006 Referee for Piedmont Region (Italy), Bando per Progetti Strategici di Ricerca Industriale

2005 Referee for European Commission 6th FP – NEST and MARIE CURIE actions

4

2005 Referee for European Commission 6th FP – eTEN actions

Since 2002 Reviewer of the journals: Minerva Anestesiologica, Intensive Care Medicine, Critical Care

medicine, BMC Anesthesiology, Int J of Nanomedicine, American Hearth Journal, Redox

Report, Thorax, J of Inflammation, J Clinical Monitoring and Computing, J of Pain Research

TECNICAL SKILLS SCIENTIFIC BOARDS

2016-18 Member of the Board of the SIAARTI (Società Italiana di Anestesia, Analgesia, Rianimazione e Terapia Intensiva)

5

Since 2016 Member of the Scientific Committee of the European Society of Anesthesiology, subcommittee 2, ambulatory surgery

RESEARCH PROJECTS

Since 2013

2011-2012

2010-2011

2010-2012

2015-2017

2007-2011

2006

2004

2004

2002

2003

2002

2001

2000

1992-99

Member of the Steering Committee of the PROBESE (protective ventilation and postoperative pulmonary complications in obese patients), a prospective multicenter

randomized international cohort study, conducted by the European Society of

Anesthesiology

National coordinator of the LAS VEGAS (Local assessment of ventilator

management during general anesthesia for surgery and affects on postoperative

pulmonary complications) a prospective multicenter international cohort study,

conducted by the European Society of Anesthesiology

Local coordinator of the PROHVILO study (Protective ventilation during general

anaethesia for open abdominal surgery) a prospective multicenter international

cohort study sponsorized by the Academish Medish Centrum – University of

Amsterdam (NL) and conducted by the European Society of Anesthesiology National coordinator of the PAIN OUT (postoperative pain research project), a

prospective multicenter international cohort study founded by the European

Commission and conducted by the European Society of Anesthesiology Research Grants, Active as Co-Investigator:

“Pre.C.I.O.U.S. (Predictive Computer aided scoring support system): Sistema per

l’ottimizzazione delle procedure e dei percorsi assistenziali nella pratica clinica ospedaliera”, source Italian gouvernement, Regione Puglia, project I4W9R64, start 19.11.2015 end 18.11.2017

Evaluation and validation of new devices for monitoring and extracorporeal treatment

of patients with severe sepsis”, source Italian Gouvernemnt - Regione Puglia “ARDS and mechanical ventilation: respiratory markers", source University of

Foggia. “Pharmacogenetics of the analgesic drugs in the post-operative patients" source

University of Foggia. PRIN 2004 - "Identificazione della componente eredo-familiare nella patogenesi

dell’ictus ischemico giovanile” , source Ministero dell’Università; PRIN 2002 - "Effects of general anesthesia on oxidative stress in patients with pre-

eclampsia undergoing Caesarean section ", source Ministero dell’Università

Research Grants, Active as Principal Investigator:

“Effects of general anesthesia on oxidative stress in patients undergoing Caesarean

section" source University of Foggia”. “Effects of opioids on oxidative stress", source University of Foggia “Effects of opioids on surgical stress", source University of Foggia "Effects of various systems of humidification of the airways on the tracheobronchial

cells", source University of Foggia reference investigator for the Dept of Anaesthesiology and Intensive Care, involved

in the epidemiology studies launched from the Mario Negri Institute, Milano, Italy on

behalf of the Gruppo Italiano Valutazione Interventi in terapia Intensiva (GiViTi).

6

1990-99

reference investigator for the Dept of Anesthesiology and Intensive Care, involved in

Italian and international multi-centre studies on the antibiotic therapy.

OTHER SKILLS

2013-16

2012-2013

2000-2006

SINCE 1990

SINCE 2001

SINCE 1999

TEACHING RESPONSIBILITIES

Teacher in Doctorate

Doctorate in “Medicina sperimentale e rigenerativa” University of Foggia, 2013

Doctorate in “Scienze neuropsichiatriche, cardiopneumologiche e dell’invecchiamento”,

University of Foggia, 2012

Doctorate in “Didattica della medicina”, University of Foggia,

Teaching in Residency Schools

Residency School in Anaesthesia and Intensive Care, Medical School, University of

Bari, Italy

Medical School, University of Foggia:

Residency School in Anesthesia and Intensive Care;

Residency School in General Surgery,

Residency School in “Chirurgia dell’Apparato Digerente”

Residency in Geriatrics

Residency School in Plastic Surgery

Residency in Thoracic Surgery

Teaching in School of medicine, University of Foggia

Course of Pain Therapy

Course of Intensive Care

Course of Hyperbaric Medicine

Course of Anaesthesia

PERSONAL INTERESTS

SINCE 2008 SOMMELIER CERTIFIED FORM AIS (ASSOCIAZIONE ITALIANA SOMMELIERS)

MEMBERSHIPS

Società Italiana di Anestesia, Analgesia, Rianimazione e Terapia Intensiva (SIAARTI)

European Society of Intensive Care medicine (ESICM)

European Society of Anaesthesiology (ESA)

BIBLIOGRAPHY

2016

1. Bellanti F, Mirabella L, Mitarotonda D, Blonda M, Tamborra R, Cinnella G, Fersini A,

Ambrosi A, Dambrosio M, Vendemiale G, Serviddio G.

Propofol but not sevoflurane prevents mitochondrial dysfunction and oxidative stress by

limiting HIF-1α activation in hepatic ischemia/reperfusion injury.

Free Radic Biol Med. 2016 May 3;96:323-333. doi: 10.1016/j.freeradbiomed.2016.05.002.

[Epub ahead of print] PubMed PMID: 27154980.

7

2. Pesenti A, Musch G, Lichtenstein D, Mojoli F, Amato MB, Cinnella G, Gattinoni L,

Quintel M.

Imaging in acute respiratory distress syndrome.

Intensive Care Med. 2016; 42(5), 686-98 Review. PubMed PMID: 27033882. DOI

10.1007/s00134-016-4328-1

3. Cutuli SL, Artigas A, Fumagalli R, Monti G, Ranieri VM, Ronco C, Antonelli M;

EUPHAS 2 Collaborative Group.. Polymyxin-B hemoperfusion in septic patients: analysis

of a multicenter registry.

Ann Intensive Care. 2016 Dec;6(1):77. doi:10.1186/s13613-016-0178-9. PubMed PMID:

27502196.

4. Nappi L, Angioni S, Sorrentino F, Cinnella G, Lombardi M, Greco P. Anti-Mullerian

hormone trend evaluation after laparoscopic surgery of monolateral endometrioma using a

new dual wavelengths laser system (DWLS) for hemostasis.

Gynecol Endocrinol. 2016 Jan;32(1):34-7. doi: 10.3109/09513590.2015.1068754. Epub

2015 Aug 28. PubMed PMID: 26359914.

5. Di Mussi R, Spadaro S, Mirabella L, Volta CA, Serio G, Staffieri F, Dambrosio M,

Cinnella G, Bruno F, Grasso S.

Impact of prolonged assisted ventilation on diaphragmatic efficiency: NAVA versus PSV.

Crit Care. 2016 Jan 5;20(1):1. doi: 10.1186/s13054-015-1178-0

2015

6. Fletcher, D, Stamer, U.M., Pogatzki-Zahn, E., Zaslansky, R., Tanase, N.V., Perruchoud, C.,

Kranke, P., Komann, M. Lehman, T., Lavand homme, P., Vercauteren, M., Meissner, W.,

Iohom, G., Cinnella, G., Aurilio, C., Belii, A., Filipescu, D., Rehberg-Klug, B., Decostered, I.,

Suter, M.R., Blumenthal, S., Puig, M., Garcia-Filoso, A., Brandner, B., Varvinskiy, A.M.,

Lisnyy, I., Kuchyn, I.

Chronic postsurgical pain in Europe: An observational study European J Anesthesiol, 2015 , 32(10): 725-34

7. D'Ambrosio A, Spadaro S, Natale C, Cotoia A, Dambrosio M, Cinnella G.

Continuous spinal analgesia with levobupivacaine for postoperative pain management:

Comparison of 0.125% versus 0.0625% in elective total knee and hip replacement: A

double-blind randomized study.

J Anaesthesiol Clin Pharmacol. 2015 Oct-Dec;31(4):478-84. doi: 10.4103/0970-

9185.169066.

8. Cinnella G, Grasso S, Raimondo P, D'Antini D, Mirabella L, Rauseo M, Dambrosio M.

Physiological Effects of the Open Lung Approach in Patients with Early, Mild, Diffuse

Acute Respiratory Distress Syndrome: An Electrical Impedance Tomography Study.

Anesthesiology. 2015 Nov;123(5):1113-21. doi: 10.1097/ALN.0000000000000862.

9. Enrolling patients into multiple trials: it is time for glastnost

Cinnella G. 2015 Crit Care Med 43(2):495-6.

8

Doi: 10.1097/CCM.0000000000000756

2014

10. High versus low positive end-expiratory pressure during general anaesthesia for open

abdominal surgery (PROVHILO trial): a multicenter randomized controlled trial.

PROVE Network Investigators for the Clinical Trial Network of the European Society of

Anesthesiology. *, indicates local principal investigator

W. Schmid *, L. De Baerdemaeker, S.De Hert*, B. Heyse, J. Van Limmen, JP. Mulier*, D.

Velghe*, L. Jamaer*, J. Vandenbrande, G. Bugedo, *, J. Florez, T. Goranovi

, B. Mazul–Sunko *, T. Bluth, M. Gama de Abreu*, A. Güldner, T. Kiss, T. Koch, PM Spieth, C.

Uhlig, J. Yaqub, B. Bastin, J. Geib, M.S. Schaefer, M. Weiss, T.A. Treschan*, A.W. Reske, P.

Simon, H. Wrigge*, A.Brodhun Marion Ferner, E.Hartmann, R. Laufenberg-Feldmann*, L. Strys,

C. Putensen*, E. De Robertis *, V. Perilli, R. Proietti*, B. Amantea, S. Caroleo*, F.Tropea, A.

Bacuzzi, P. Severgnini*, M.Vanoni, G. Cinnella*, G. Caggianelli, D.DAntini, D. La Bella, G.

Mollica, A. Cortegiani, A. Giarratano*, F.Montalto, S.M.Raineri, B. Barberis, C. Celentano, M.

Grio, L. Spagnolo*, A. Gratarola, A. Molin*, G.Pellerano, S. Pezzato, R.Rusca, G. Della Rocca*,

L.D.J. Bos, S.N.T. Hemmes, M.W. Hollmann, M.J. Schultz*, A. Brunelli*, A. Marti, V. Cegarra,

A.Merten, Mª V.Moral, A. Parera, Mª C. Unzueta*, S. Sabaté*, P. Sierra, J. F Mayoral, M. Prieto,

M. Granell Gil*, C. Minguez Marín, G.H. Mills*, P. Bodger*, M. F. Vidal Melo*, D. Sulemanji,

J.Sprung

Lancet. 2014 Aug 9;384(9942):495-503. doi: 10.1016/S0140-6736(14)60416-5. Epub 2014 Jun 2

11. Polymyxin B Hemoperfusion in Clinical Practice: The Picture from an Unbound

Collaborative Registry. The Early Use of Polymyxin B Hemoperfusion in the Abdominal Sepsis

2 (EUPHAS2) Collaborative Group Antonelli M, Bello G, Maviglia R, Cutuli SL, Ronco C, Cruz D, Ranieri VM, Martin EL, Fumagalli

R, Monti G, Vesconi S, Casella G, Piccinni P, Debitonto M, Fasanella E, Monza G, Blasetti AG,

Coletta R, D'Ambrosio M, Cinnella G, Mattei A, Piscitelli E, Centonze G, Cucurachi M, Altieri G,

Del Rosso G, Polidoro M, Mani RK, Stigliano N, De Trana L, Pittella G, Paternoster G, Caione R,

Puscio D, Singh O, Pulito G, Idra AS, Sathe P, Congolani D, Falzetti G, Vecchiarelli P, Giunta F,

Forfori F, Castiglione G, Nangia V, Madonna R, Urbano C, Pezza B, Sachin G, D'Costa PM, Capra

C, Crema L, Tamayo L, Srivanas S, Singh YP.

Blood Purif. 2014. 37:S1:22-25

12. p-Hydroxyphenylpyruvate, an intermediate of the Phe/Tyr catabolism, improves

mitochondrial oxidative metabolism under stressing conditions and prolongs survival in rats

subjected to profound hemorrhagic shock.

Antonella Cotoia, Rossella Scrima, Julia V. Gefter, Claudia Piccoli, Gilda Cinnella, Michele

Dambrosio, Mitchell P. Fink, Nazzareno Capitanio

Plos One, 2014, 9(3):e90917-27 IF 3.73

13. A Prospective, Randomized Comparative Study of Respiratory and Hemodynamic Monitoring

during Colonoscopy using Remifentanyl Versus Propofol/Fentanyl

Giuseppina Mollica, Lucia Mirabella, Savino Spadaro, Nicola Muscatiello, Nicola Della

Valle,Gabriele Racanelli, Girolamo Caggianelli, Pasquale Del Vecchio, Carmine Panella, Enzo

Ierardi, Michele Dambrosio and Gilda Cinnella

J Anesth Clin Res, 2014, 5.381: doi 10.4172/2155-6148. 1000381 Scopus

9

2013

14. Cinnella G, Grasso S, Spadaro S, Rauseo M, Mirabella L, Salatto P, Capraris AD, Nappi L,

Greco P, Dambrosio M.

Effects of recruitment maneuver and positive end-expiratory pressure on respiratory mechanics and

transpulmonary pressure during laparoscopic surgery.

Anesthesiology. 2013;118(1):114-22.

15. Pugliese LP, Cinnella G, Raimondo P, De Capraris A, Salatto P, Sforza D, Menga R,

D’Ambrosio A, Fede RN, D’Onofrio M, Consoletti L, Malvasi A, Brizzi A, Dambrosio M

Implementation of Epidural Analgesia for Labor: is the standard of effective analgesia reachable in

all women? An audit of two years

European Review for Medical and Pharmacological Sciences, 2013;9:1262-8

16. De Filippis V, D’Antini D, Cinnella G, Dambrosio M, Schiraldi F, Procacci V.

End-tidal Arterial PCO2 gradient in patients with severe hypercapnia undergoing non-invasive

ventilation.

Open access Emergency Medicine, 2013;5:1-7

17. Gambatesa M, D’Ambrosio A, D’Antini D, Mirabella L, De Capraris A, Iuso S, Bellomo A,

Macchiarola A, Dambrosio M, Cinnella G

Counseling, quality of life and acute postoperative pain in elderly patients with hip fracture.

Journal of multidisciplinary healthcare, 2013;6:335-346

18. D’Ambrosio A, Spadaro S, Mirabella L, Natale C, Cotoia A, De Capraris A, Menga R,

Salatto P, Malvasi A, Brizzi A, Tinella A, Dambrosio M, Cinnella G

The anaesthetic and recovery profile of two concentrations (0.25% and 0.50%), of intrathecal

isobaric Levobupivacaine for combined spinal-epidural (CSE) anaesthesia in patients undergoing

modified Stark method caesarean delivery: a double blinded randomized trial.

European Review for Medical and Pharmacological Sciences, 2013; 17:3229-36.

2012

19. Bellanti F, Mirabella L, Eronia N, Cinnella G, Tamborra R, Dambrosio M, Altomare E:

Propofol, but not sevoflurane, protects mitochondria and liver function after ischemia-reperfusion

injury.

Journal of Hepatology, 2012, 56: S71-S71

20. Cacciapaglia M. Cinnella G. Schiraldi R, Cormio L, Vetuschi P, Cotoia A, Mirabella L,

Dambrosio M.

Combined sequential spinal epidural anaesthesia: a prospective study

Anesthesia and Clinical research 2012, 3:8 http://dx.doi.org/104172/2155-6148.1000232

2011

21. A. De Capraris, G. Cinnella, A. Marolla, P. Salatto, S. Da Lima, P. Vetuschi, L. Consoletti,

L. Gesualdo and M. Dambrosio

10

MICRO OPIOID RECEPTOR A118G POLYMORPHISM AND POST-OPERATIVE PAIN:

OPIOIDS EFFECTS ON HETEROZIGOUS PATIENTS

Int J Immunopathol Pharmacol, 2011, 24:993-1004.

2010

22. Cela O, Piccoli C, Scrima R, Quarato G, Marolla A, Cinnella G, Dambrosio M, Capitanio

N.

Bupivacaine uncouples the mitochondrial oxidative phosphorylation, inhibits respiratory chain

complexes I and III and enhances ROS production: results of a study on cell cultures.

Mitochondrion 2010; 10:487-496.

23. Schortgen F, Girou E, Deye N, Brochard L; CRYCO Study Group (collaborators 200)

Do hypooncotic fluids for shock increase the risk of late-onset acute respiratory distress syndrome?.

Intensive Care Med. 2010;36(10):1724-34.

Prof. Gilda CINNELLA is coauthor, as listed in the appendix of this paper

2008

24. Galante D, Pellico G, Meola S, Caso A, De Capraris A, Milillo R, Mirabile C, Olivieri M,

Cinnella G, Dambrosio M.

Hemodynamic effects of levobupivacaine after pediatric caudal anesthesia evaluated by

transesophageal doppler.

Paediatr Anaesth. 2008 Nov;18(11):1066-74

25. Cinnella G, Grasso S, Natale C, Sollitto F, Cacciapaglia M, Angiolillo M, Pavone G,

Mirabella L, Dambrosio M.

Physiological effects of a lung-recruiting strategy applied during one-lung ventilation.

Acta Anaesthesiol Scand. 2008 Jul;52(6):766-75.

26. Schortgen F, Girou E, Deye N, Brochard L; CRYCO Study Group (collaborators 200)

The risk associated with hyperoncotic colloids in patients with shock.

Intensive Care Med. 2008 Dec;34(12):2157-68.

Prof. Gilda CINNELLA is coauthor, as listed in the appendix of this paper

2007

27. Gilda Cinnella, MD; Salvatore Meola, MD; Aurelio Portincasa, MD; Domenico Parisi, MD;

Francesco Morgese, MD; Giovanna Pavone, MD; Michele Dambrosio, MD, PhD

Sedation-analgesia during office-based plastic surgery procedures: comparison of two opioids

regimens.

Plast Reconstr Surg, 2007, 119(7):2263-2270.;

28. Marucci M, Cinnella G, Brienza N, Perchiazzi G, and Fiore T:

Patient-requested Neuraxial Analgesia for Labor: Impact on Rates of Cesarean and Instrumental

Vaginal delivery.

Anesthesiology, 2007, 106:1035-45.

29. Galante D, Pellico G, Federico A, Schiraldi R, Matella M, Milillo R, Dambrosio M,

Cinnella G:

Postextubation adverse events in children undergoing general anesthesia.

11

Paediatr Anaesth. 2007 Feb;17(2):192; author reply 193.

30. Galante D, Pellico G, Federico A, Schiraldi R, Matella M, Milillo R, Dambrosio M,

Cinnella G:

Anesthesia for congenital insensitivity to pain with anidrosis.

Paediatr Anaesth. 2007 Feb;17(2):192; author reply 193.

31. Galante D, Dambrosio M, Cinnella G, Pellico G, Federico A, Pugliese P, Sforza D:

Volatile agents and caudal block.

Paediatr Anaesth. 2007 Apr;17(4):398-399.

32. G. Cinnella, G. Vendemiale, M. Dambrosio, G. Serviddio, P.L. Pugliese, G. Aspromonte,

and E. Altomare.

EFFECT OF PROPOFOL, SEVOFLURANE, AND DESFLURANE ON SYSTEMIC REDOX

BALANCE

Int J Immunopathol Pharmacol, 2007 Jul-Sep;20(3):585-93.

2006

33. Jaundice in critical illness: promoting factors of a concealed reality.

Nicola Brienza, Lidia Dalfino, Gilda Cinnella, Caterina Diele, Francesco Bruno, Tommaso

Fiore

Int Care Med, 2006, 32(2): 267-274.

34. Dalfino L, Malcangi V, Cinnella G, Brienza N:

Abdominal hypertension and liver disfunction in intensive care unit patients: an ‘on-off’

phenomenon?

Transplantation Proceedings, 2006;38:838-40

2005

35. Cinnella G, Giardina C, Fischetti A, Lecce G, Fiore MG, Serio G, Carravetta G, Dambrosio

M, Fiore T.

Airways humidification during mechanical ventilation. Effects on tracheobronchial ciliated cells

morphology.

Minerva Anestesiol. 2005 Oct;71(10):585-93.

2004

36. Cinnella G, Dambrosio M, Brienza N, Tullo L, Fiore T.

Transesophageal echocardiography for diagnosis of traumatic aortic injury: an appraisal of the

evidence.

J Trauma. 2004 Dec;57(6):1246-55.

2002

37. Dambrosio M, Tullo L, Moretti B, Patella V, Simone C, Calò MN, Dalfino L, Cinnella G.

Modificazioni emodinamiche e respiratorie in corso di protesi di anca e di ginocchio: studio

ecografico.

Minerva Anestesiologica, 68:537-547, 2002.

2001

38. G Cinnella, M Dambrosio, N Brienza, R Giuliani, F Bruno, T Fiore, A Brienza:

12

Independent lung ventilation in patients with unilateral pulmonary contusion. Monitoring with

Compliance and EtCO2.

Intensive Care Med, 27:1860-67, 2001.

1997

39. M Dambrosio, N Brienza, G Cinnella

Right ventricular myocardial function in ARF patients. Peep as a challenge for the right heart.

Reply:

Int Care Med 23; 2:237-238, 1997, Springer-Verlag, Berlino, Germania.

1996

40. Cinnella G, Conti G, Lofaso F, Lorino H, Harf A, Lemaire F, Brochard L

Effects of assisted ventilation on the work of breathing: volume-controlled versus pressure-

controlled ventilation.

Am J Respir Crit Care Med, 153:1025-33, 1996, NY, USA.

41. Conti G, Cinnella G, Barboni E, Lemaire F, Harf A, Brochard L

Estimation of occlusion pressure during assisted ventilation in patients with intrinsic PEEP. Am J

Respir Crit Care Med, 154:907-912, 1996, NY, USA.

42. Villafane MC, Cinnella G, Lofaso F, Isabey D, Harf A, Lamaire F, Brochard L

Gradual reduction of endotracheal tube diameter during mechanical ventilation via different

humidification devices.

Anesthesiology, 85:1341-1349, 1996, Hagerstown, Maryland, USA.

43. Dambrosio M, Cinnella G, Brienza N, Ranieri VM, Giuliani R, Bruno F, Fiore T, Brienza

A

Effects of positive end-expiratory pressure on right ventricular function in COPD patients during

acute ventilatory failure.

Int Care Med, 22:923-932, 1996, Springer-Verlag Ed, Berlino, Germania.

44. Dambrosio M, Fiore G, Brienza N, Cinnella G, Marucci M, Ranieri VM, Greco M, Brienza

A

Right ventricular myocardial function in ARF patients. Peep as a challenge for the right heart.

Int Care Med, 22: 772-780, 1996, Springer-Verlag Ed, Berlino, Germania.

45. Brienza N, Dambrosio M, Cinnella G, Conte M, Puntillo F, Bruno F:

Effects of PEEP in intrathoracic and extrathoracic blood volumes evaluated with the COLD system

in patients with acute respiratory failure. Preliminary study.

Minerva anesthesiologica, 2006;62:235-42.

1995

46. Gattinoni L, Brazzi L, Pelosi P, Latini R, Tognoni G, et al for the SvO2 collaborative group:

A trial of goal-oriented hemodynamic therapy in critically ill patients.

New Engl J Med, 333; 16:1025-32, 1995, Boston, USA.

Prof. Gilda CINNELLA is coauthor, as listed in the appendix of this paper

13

47. Gattinoni L, Brazzi L, Latini R, Tognoni G, et al for the SvO2 collaborative group:

The SVO(2) study- general design and results of the feasibility phase of a monitoring, randomized

trial of 3 different hemodynamic approaches and 2 monitoring techniques in the treatment of

critically ill patients.

Controlled Clinical Trials, 1993;16:74-87

Prof. Gilda CINNELLA is coauthor, as listed in the appendix of this paper.

1993

48. V Marco Ranieri, Rocco Giuliani, Gilda Cinnella, Caterina Pesce, Niki Brienza, Eustachio

L. Ippolito, Vincenzo Pomo, Tommaso Fiore, Steward B. Gottfried, and Antonio Brienza

Physiological effects of positive end-expiratory pressure in patients with chronic obstructive

pulmonary disease during acute ventilatory failure and controlled mechanical ventilation.

Am Rev Resp Dis, 147:5-13, 1993, NY, USA.

49. Dambrosio M, Giuliani R, Ranieri VM, Brienza N, Cinnella G, Brienza A:

Right-ventricular function in COPD patients during acute ventilatory failure- Effects of PEEP

Am Rev Resp Dis, 1993; 147:S608, NY, USA.

REVIEW ARTICLES

1998

50. Cinnella G

Use of CT scan and transesophageal echocardiography in blunt thoracic trauma.

Intensive Care Med, 24:986-987, 1998, Springer-Verlag, Berlino, Germania.

CASE REPORT

2000

51. Gilda Cinnella, Michele Dambrosio, Nicola Brienza, Francesco Bruno, Antonio Brienza: Compliance and capnography monitoring during independent lung ventilation: report of two cases.

Anesthesiology, 93:275-278, 2000, Hagerstown, Maryland, USA.

2009

52. Galante D, Meola S, Cinnella G, Dambrosio M.

Regional caudal blockade in Pediatric patient affected by Joubert Sindrome. Case report.

Acta Anaesthesiol Scand, 2009 53(5):693-4.

2010

53. Galante D, Meola S, Milillo R, Pellico G, Cinnella G, Dambrosio M.

Remifentanil infusion reduces desflurane airway irritation via proseal laryngeal mask in children.

Paediatr Anaesth 2010; 20: 958-76.

2013

54. Consoletti L, Cotoia A, Cinnella G, Dambrosio M.

Transient global amnesia after epiduroscopy in a failed back surgery syndrome patient: Case

report

Health, 2013; 5:7-11. http://dx.doi.org/10.4236/health.2013.511A1002 ISSN Online: 1949-

5005; Website: http://www.scirp.org/journal/health

14

LETTER TO THE EDITOR

1998

55. Cinnella G, Dambrosio M, Brienza N, Ranieri VM:

Reexpansion pulmonary edema with acute hypovolemia.

Intensive Care Med, 24:1117-1121, 1998, Springer-Verlag, Berlino, Germania.

56. Cinnella G.

Towards the VI european community framework programme and the European research area.

Intensive Care Medicine, 28:1678-79, 2002.

CONGRESS COMMUNICATIONS

1987

57. Dambrosio M, Fiore G, Cinnella G, Marucci M, La Gioia V, Spagnolo A

Effetti emodinamici della ventilazione artificiale nella insufficienza respiratoria acuta.

Atti del IV Simposio Meridionale Anestesia, Rianimazione e Terapia antalgica; Catanzaro, 3-5

giugno 1987, pp:143-153, Vincenzo Ursini Ed.

58. Cinnella G, Dambrosio M, Fiore G, Marucci M, Sorrentino G, Fiore T Confronto tra due metodi di rilevazione della compliance dell'arteria polmonare in cani sottoposti a

incrementi di Peep.

Atti del IV Simposio Cuore e Anestesia, Roma 12-14 novembre 1987, pp:291-294, CIC Edizioni

Internazionali, Roma.

1988

59. A Brienza, F Bruno, M Dambrosio, M Marucci, G Belpiede, G Fiore, G Cinnella

Frazione d’eiezione ventricolare destra: tecniche di valutazione ed utilità diagnostica.

Atti del XVIII Corso nazionale di aggiornamento in Rianimazione e Terapia Intensiva, Milano 5-7

maggio 1988, pp:177-189, Editore Piccin.

1990

60. Brienza A, Cinnella G, Dambrosio M.

Attualità in tema di Ipertensione Polmonare.

Proceedings 2nd post-graduate course in Anesthesia and Intensive Care, Gismondi, Caione,

Colonna, De Razza eds, Vol I; pp:277-322, 1990, Casa Ed Salentina, Galatina (Le).

1991

61. R Giuliani, G Carravetta, VM Ranieri, M Dambrosio, G Cinnella G Barbone and A Brienza

Clinical usefulness of a double-model mathematical analysis of P/V curve.

Anaesthesia and Intensive Care in Italy, supplement of Acta Anaesthesiologica Italica, Ed. La

Garangola, Padova, 42:11-20, 1991.

62. A Brienza, G Cinnella, M Dambrosio, N Brienza, M Massaro, M Marucci

Incidence of pulmonary arterial hypertension and right ventricular impairement in moderate and

severe acute respirarory failure.

Anaesthesia and Intensive Care in Italy, supplement of Acta Anaesthesiologica Italica, Ed. La

Garangola, Padova, 42:45-55, 1991.

15

63. Marcella Greco, N Brienza, Gilda Cinnella, M Dambrosio, G Fiore, M Marucci, R Giuliani

Significato prognostico dell'ipertensione polmonare nella insufficienza respiratoria acuta: studio su

114 pazienti.

Minerva Anestesiol, 57:944-945, 1991, Ed Minerva Medica, Torino.

64. A Brienza, G Cinnella, M Dambrosio, N Brienza, M Marucci, G Fiore, M Massaro

Rapporti fra circolo polmonare e ventricolo destro in terapia intensiva.

Impegno Ospedaliero, XII:19-27, 1991.

65. N Brienza, M Dambrosio, VM Ranieri, Gilda Cinnella, Giuliana Primiceri, Marcella Greco,

F Bruno

Is SvO2 a reliable indicator of oxygen delivery when PEEP is applied in septic ARF patients?

Proceedings of Recent advances in Anaesthesia, Pain, Intensive Care and Emergency, A.P.I.C.E.

ed, Trieste, pp 32-35, 1991.

1992

66. A Brienza, VM Ranieri, M Dambrosio, N Brienza, Gilda Cinnella, R Giuliani, Maria

Massaro

Effetti della PEEP su funzione ventricolare destra, volume polmonare e pressione intratoracica nei

pazienti BPCO.

Minerva Anestesiol, 58:361-362, 1992, Ed Minerva Medica, Torino.

67. Gilda Cinnella, Caterina Pesce, Giovanna Longo, M Ranieri, R Giuliani, T Fiore

Incidenza di mortalità in rapporto al GCS nel trauma cranico. Studio retrospettivo in UTI. Minerva

Anestesiol, 58:711-712, 1992, Ed Minerva Medica, Torino.

68. A Brienza, G Cinnella, M Dambrosio, G Fiore

VCI and right ventricular function in different clinical conditions.

Proceedings of Recent Advances in Anaesthesia Pain, Intensive Care and Emergency, Trieste,

pp:432-440, 1992.

1993

69. A Brienza, F Bruno, G Cinnella, M Sisto

Trattamento del traumatizzato toracico.

Minerva Anesthesiol, 59: 145-154, 1993, Ed Minerva Medica, Torino.

1994

70. Cinnella G, Brienza A

Monitoraggio del weaning dalla ventilazione polmonare differenziale.

Atti della 3° settimana di aggiornamento in Anestesia Rianimazione, Gismondi, Caione, Colonna,

Puscio eds, Alimini (LE) 19-26 giugno 1994, pp 27-34;

1995

71. Brienza N, Dambrosio M, Cinnella G, Conte M, Puntillo N, Bruno F

Effetti della PEEP sui volumi ematici intratoracico e totale valutati con sistema COLD in pazienti

con insufficienza respiratoria acuta. Studio preliminare.

16

Minerva Anestesiologica, 62:235-242, 1996, Edizioni Minerva Medica, Torino.

1998

72. G. Cinnella, M Dambrosio

Effects of different humidification devices on endotracheal tube obstruction.

Proceedings of Simposio Mostra Anestesia Rianimazione e Terapia Intensiva (SMART); Braschi,

Gattinoni, Pesenti, Raimondi eds, Springer, Milano, pp 120-122, 1998;

73. Brienza A, Cinnella G

Trauma toracico e danno polmonare a prevalenza monopolmonare.

Aggiornamenti in Anestesia, Rianimazione e Terapia Antalgica; Martinelli, Pasetto, Mattia,

Pellegrini eds, CIC edizioni internazionali, Roma, pp 128-130, 1998;

74. G Cinnella, SM Maggiore, G Fanelli, N Di Venosa

Ventilazione polmonare differenziata nei traumi toracici.

Proceedings of XII Simposio Meridionale di Anestesiologia e Rianimazione, Minuto ed, Editoriale

Bios, Cosenza, pp 153-158,1998.

1999

75. G Cinnella, C Giardina, M Dambrosio, C Gadaleta, MG Fiore, G Lecce, F Bruno:

Airways humidification durino mechanical ventilation: HME vs heated humidifiers.

Proceedings of Meeting Anestesia Rianimazione Emergenza, Gismondi, Caione, Colonna, Puccio

eds, Editrice Salentina, Galatina, pp 413-416,1999;

76. Dambrosio M, Carravetta G, Milella D, Coniglio C, Cinnella G , Lauta E:

Esperienza di avvio di un centro trapianti di fegato nel Sud dell’Italia. Il ruolo dell’anestesistta

rianimatore.

Proceedings of Meeting Anestesia Rianimazione Emergenza, Gismondi, Caione, Colonna, Puccio

eds, Editrice Salentina, Galatina, pp 473-478,1999;

77. Nicola Brienza, Michele Dambrosio, Gilda Cinnella:

Hemodynamic changes during major liver surgery.

Proceedings of 2nd

International Meeting “Dialogues on Anaesthesia and Intensive Care”, Napoli, 4-

6 febbraio, 1999, pp:187-189.

2000

78. N Brienza, M Dambrosio, G Cinnella: Hemodynamic pressumetric and volumetric values during liver surgery.

Proceedings of 3rd

Utinensis Meeting “Liver Anaesthesia and Intensive Care”, Tarvisio, 10-11

marzo 2000, pp:67-69.

ORIGINAL ARTICLES ISSUED FROM MULTICENTER STUDIES

prof. Gilda CINNELLA IS coauthor of all these papers. The list of coauthore is in the appendix of

each paper.

1992

17

79. GiViTi:

Risultati preliminari di uno studio multicentrico sui profili di cura e sull’outcome di pazienti

ricoverati in reparti di Terapia intensiva.

Minerva Anestesiol 58; 10:927-929, Edizioni Minerva Medica, Torino.

80. G Apolone, L Brazzi e C Pesce a nome del GIVITI:

Studio multicentrico sui profili di cura e sull'outcome di pazienti ricoverati in reparti di Terapia

Intensiva italiani.

Lista dei coautori in appendice.

Minerva Anestesiol, 58:1297-1303, 1992, Edizioni Minerva Medica, Torino.

81. G Iapichino, GIRTI I e II (Gruppo Italiano di Ricerche in Terapia Intensiva):

Intensive Medicine in Italy: Metropolitan Epidemiological Observatory - 1988-1991. Lista dei

coautori in appendice.

Proceedings of Recent Advances in Anaesthesia Pain, Intensive Care and Emergency, A. Gullo ed,

Trieste, 1992, pp:353-355.

1993

82. Gruppo Italiano Multicentrico di Ricerche in Terapia Intensiva (GIRTI II):

La medicina intensiva in area metropolitana- Update 1992. Lista dei coautori in appendice.

Minerva Anestesiol, 59: 389-394, 1993, Edizioni Minerva Medica, Torino.

83. Gruppo Italiano Multicentrico di Ricerche in Terapia Intensiva (GIRTI II):

Conversione tra APACHE II e SAPS. Lista dei coautori in appendice.

Minerva Anestesiol, 59:451-453, 1993, Edizioni Minerva Medica, Torino.

84. GIVITI investigators:

Variation in health care practices and outcome: results from a cohort of patients cared for in 114

italian intensive care units.

Lista dei coautori in appendice

Minerva Anesthesiol, 59: 227-228, 1993, Edizioni Minerva medica, Torino.

85. Torri G, Gattinoni L, Langer M, Salvo I, Musicco M, De Cian W, Piadena R:

Multicenter Epidemiological Study on the incidence of sepsis - Presentation of the research project.

Lista dei coautori in appendice.

Proceedings of Recent Advances in Anaesthesia Pain, Intensive Care and Emergency, A. Gullo ed,

Trieste, 1993, pp:725-727.

86. Lemeshow S, Teres D, Klar J, Avrunin JS, Gehlbach SH, Rapoport J:

Mortality prediction model (MPM II) based on an international cohort of intensive care unit

patients. Lista dei coautori in appendice.

JAMA, 270:2478-2486, 1993, Chicago,USA.

87. Le Gall JR, Lemeshow S, Saulnier F:

A new simplified acute physiology score (SAPS II) based on a european/north american multicenter

study. Lista dei coautori in appendice.

JAMA, 270:2957-2963, 1993, Chicago, USA.

18

88. L Brazzi, C Pessina a nome del GiViTi:

La Terapia intensiva in Italia: risultati dal GiViTi.

Atti del IV Convegno di Sudio “Rianimazione Cardiopolmonare e Cerebrale: Attualità ed

esperienza”. Castello di Sartirana (PV) 18 settembre 1993, pp:155-160.

1994

89. Apolone G, Brazzi L, De Salvo G, Iapichino G, Leonetti C, Melotti R on behalf of GiViTi

investigators:

The epidemiology of Intensive Care in Italy. Lista dei coautori in appendice.

Atti dal 7th European Congress On Intensive Care Medicine, Innsbruck, 1994, p111-115, Monduzzi

Editore, Padova.

90. Apolone G, Brazzi L, De Salvo G, Iapichino G, Leonetti C, Melotti R, on behalf of GiViTi:

The epidemiology of intensive care in Italy.

Int Care Med, 20;S2:S1, 1994, Springer International, Berlino, Germania.

91. GiViTi:

Risultati dal GIVITI. Lista dei coautori in appendice

Atti della 3° settimana di aggiornamento in Anestesia Rianimazione, Gismondi, Caione, Colonna,

Puscio eds, Alimini (LE) 19-26 giugno 1994, pp 401-408, Editrice salentina, Galatina (LE).

92. Apolone G:

Sedation in Intensive Care Units: GiViTi Data. Lista dei coautori in appendice.

Proceedings of Recent Advances in Anaesthesia Pain, Intensive Care and Emergency, A. Gullo ed;

Trieste 1994; pp:93-103, 1994.

93. G Iapichino, G De Salvo, C Leonetti, G Apolone a nome del GiViTi:

Il progetto GiViTi: risultati acquisiti e attività in corso.

Atti del X Congresso Nazionale Società Italiana di Terapia Intensiva, Napoli, 14-16 aprile 1994,

pp:47-50.

1995

94. Salvo I, De Cian W, Musicco M, et al for the Sepsis Study group:

The Italian SEPSIS study: preliminary results on the incidence and evolution of SIRS, sepsis,

severe sepsis and septic shock. Lista dei coautori in appendice

Int Care Med, 21, (S2): S244-S249, 1995. Sprinter-Verlag, Berlino, Germania.

1996

95. Apolone G, Bertolini G, D’Amico R, Iapichino G, Cattaneo A, De Salvo G, Melotti RM:

The performance of SAPS II in a cohort of patients admitted to 99 Italian ICUs: results from

GiViTi. Lista dei coautori in appendice

Int Care Med, 22: 1368-78, 1996, Springer-Verlag, Berlino, Germania.

96. GiViTi:

19

Studio multicentrico sulla medicina intensiva in Italia: Descrizione della popolazione e dei profili di

cura.

Lista dei coautori in appendice

Nuovi Argomenti di Medicina, 12, 1:3-10, 1996, Publimedica ed.

1997

97. S Rotelli, G Iapichino, A Colombo, G Apolone, L Brazzi, E Calappi, C Leonetti, GiViTi:

Studio sequenziale per giorno indice dell’attività di reparti di Terapia Intensiva.

Lista dei coautori in appendice.

Minerva Anestesiol, 63:371-377, 1997, Edizioni Minerva Medica, Torino.

1999

98. G Bertolini, C Minelli, S Pifferi, R D’Amico:

La nutrizione artificiale nel paziente critico: cosa sappiamo?

Minerva Anestesiol, 65:464-470, 1999, Edizioni Minerva Medica, Torino.

2001

99. Iapichino G, Raddrizzani D, Bertolini G, Ferla L, Pasetti G, Pezzi A, Porta F, Mirando DR.

Daily classification of the level of care. A method to describe clinical course of illness, use of

resources and quality of intensive care assistance.

Int Care Med, 27:131-136, 2001.

100. Bertolini G, Melotti R, Romano P, Cattaneo A, Mura G, Ruggiata R, Ravizza A,

Brazzi L, Iapichino G.

Use of sedatives analgesic drugs in the first week of ICU stay. A pharmacologico-epidemiological

perspective.

Minerva Anestesiologica, 76:97-105, 2001.

2002

101. Bertolini G, Minelli C, Latronico N, Cattaneo A, Mura G, Melotti RM, Iapichino G.

The use of analgesic drugs in postoperative patients: the neglected problem of pain control in

intensive care units. An observational prospective multicenter study in 128 Italian intensive care

units.

Eur J Clin Pharmacol, 58:73-77, 2002.

102. Brazzi L, Bertolini G, Arrighi E, Rossi F, Facchini R, Luciani D.

Top-down costing: problems in determinino staff costs in intensive care medicine.

Intensive Care Medicine, 28: 1661-63, 2002.

2003

103. Bertolini G, Rossi C, Brazzi L, Raddrizzani D, Rossi G, Arrighi E, Simini B:

The relationship between labour cost per patient and the size of intensive care units: a multicenter

prospective study.

Int Care Med, 2003; 29:2307-11

2004

104. Schortgen F, Deye N, Brochard L, CRYCO Study Group.

20

Preferred plasma volume expanders for critically ill patients: results of an international survey.

Intensive Care Med. 2004 Dec;30(12):2222-9.

2008

105. Schortgen F, Girou E, Deye N, Brochard L; CRYCO Study Group.

The risk associated with hyperoncotic colloids in patients with shock

Intensive Care Med. 2008 Dec;34(12):2157-68. Epub 2008 Aug 7.

2010

106. Schortgen F, Girou E, Deye N, Brochard L; CRYCO Study Group.

Do hypoonconcotic fluids for shock increase the risk of late onset acute respiratory distress

syndrome

Intensive Care Med. 2010;36(10):1724-34. Epub 2010 May 13.

October, 31, 2016 Gilda Cinnella