WEST VISAYAS STATE UNIVERSITYCOLLEGE OF NURSING

La Paz, Iloilo City

DRUG STUDY

Name of Patient: ___mother hermonio______________ Bed/ Ward No.: __________________ Attending Physician: ________________________________________Age: ________________ Impression/ Diagnosis: _____________________________________

Name of Drug Dosage, Route, Frequency and

Timing

Mechanism of Action Indication Adverse Reaction Special Precaution Nursing Responsibilities

Generic:mefenamic acid

Brand:Harafev

Dosage:500mg/capsule

Route:PO

Frequency:Q6H

Timing:6 12 6 12

Anti-inflammatory, analgesic, and antipyretic activities related to inhibition of prostaglandin synthesis.

Relief of moderate pain.

CNS:Somnolence, headache, insomnia, fatigue, tinnitus, ophthalmic effectDermatologic: Rash pruritus, dry mucus membranes, stomatitisGI:Nausea, vomiting, dyspepsia, GI pain, diarrhea, constipation, flatulence, ulcers, GI bleeding

Use cautiously with asthma, renal or hepatic impairment, peptic ulcer disease, GI bleeding, hypertension, heart pregnancy, and lactation.

1.Note for any allergies, renal or hepatic failure, CV and GI conditions, pregnancy, and lactation.2.Check for skin color, lesions, orientation, reflexes.3. Recheck name of drug and expiration date.3.Give with milk or food when GI upset occurs.4. Encourage and ensure patient to comply with drug regimen.5. Discontinue drug if adverse effects happen.

Classification Contraindication Side EffectsFunctional:Non-steroidal Anti-inflammatory Drug

Chemical:

Contraindicated with hypersensitivity to mefenamic acid, aspirin allergy, and as treatment of preoperative pain with coronary bypass grafting.

Dizziness, tiredness, sweating

Clinical Instructor: ______Zanita Glenda A. Plaga, RN______ Reference: Karch, A. (2011). Nursing Drug Guide. Philadelphia: Lippincott Wiliams and Wilkins

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COLLEGE OF NURSINGLa Paz, Iloilo City

DRUG STUDY

Name of Patient: ____Princess Hermonio ______ Bed/ Ward No.: __________________ Attending Physician: ________________________________________Age: ________________ Impression/ Diagnosis: _____________________________________

Name of Drug Dosage, Route, Frequency and

Timing

Mechanism of Action

Indication Adverse Reaction Special Precaution Nursing Responsibilities

Generic:salbutamol

Brand:

Dosage:500mg/capsule

Route:PO

Frequency:

Timing:

Classification Contraindication Side EffectsFunctional:

Chemical:

Clinical Instructor: ______Zanita Glenda A. Plaga, RN______ Reference: Karch, A. (2011). Nursing Drug Guide. Philadelphia: Lippincott Wiliams and Wilkins

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WEST VISAYAS STATE UNIVERSITYCOLLEGE OF NURSING

La Paz, Iloilo City

DRUG STUDY

Name of Patient: ___Pricess Hermonio_______ Bed/ Ward No.: __________________ Attending Physician: ________________________________________Age: ________________ Impression/ Diagnosis: _____________________________________

Name of Drug Dosage, Route, Frequency and

Timing

Mechanism of Action Indication Adverse Reaction Special Precaution

Nursing Responsibilities

Generic:amoxicillin

Brand:

Dosage:500mg/capsule

Route:PO

Frequency:Q8H

Timing:6 2 10

Bactericidal: Inhibits synthesis of cell wall of sensitive organisms, causing cell death.

Broad spectrum for adults and children; treatment of tonsillitis and pharyngitis caused by Streptococcus pyogenes, infections due to susceptible strains of H. influenza, E. coli, Proteus mirabilis, N. gonorrheae, S. pnuemonae, Enterococcus faecalis, streptococci

CNS: lethargy, hallucinations, seizuresGI: diarrhea, abdominal pain, glossitis, stomatitis,gastritis, sore mouth and furry tongue, pseudomembranous colitis,enterocolitis, bloody diarrheaGU:NephritisHematologic: Anemia, thrombocytopenia, leukopenia, neutropenia, prolonged bleeding time.Others: Superinfections, fever wheezing vaginitis

Use cautiously with renal disorders, pregnant women and lactating women.

1.Note for any allergies to penicillin, cephalosphorins and other allergens , renal or hepatic failure, CV and GI conditions, pregnancy, and lactation.2.Culture infected area priortreatment.3. Ensure compliance to drug regimen, ensure around-the-clock doding.4. Provide health teachings susch as importance of not self-medicating.5. Tell client to report signs of adverse reactions and immediately seek consultation.

Classification Contraindication Side EffectsFunctional:Antibiotics

Chemical:

Contraindicated with hypersensitivity to penicillin, cephalosphorins and other allergens.

Nausea, vomiting, rash

Clinical Instructor: ______Zanita Glenda A. Plaga, RN______ Reference: Karch, A. (2011). Nursing Drug Guide. Philadelphia: Lippincott Wiliams and Wilkins

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WEST VISAYAS STATE UNIVERSITYCOLLEGE OF NURSING

La Paz, Iloilo City

DRUG STUDY

Name of Patient: _____Princess Hermonio _________ Bed/ Ward No.: __________________ Attending Physician: ________________________________________Age: ________________ Impression/ Diagnosis: _____________________________________

Name of Drug Dosage, Route, Frequency and

Timing

Mechanism of Action Indication Adverse Reaction Special Precaution Nursing Responsibilities

Generic:albendazole

Brand:Wormhooker

Dosage:400mg/tablet

Route:PO

Frequency:BID

Timing:6 6

Antihelmethic agents are indicated for the treatmenr of infections by certain susceptible worms and are not interchangeable. Antihelmenthics interfere with metabolic processes in particular worms;

Albendazole is indicated for treatment of active lesions caused by prok tapeworm and cystic disease of the liver, lung and peritoneum caused by dog tapeworm.

GI discomfort, headache, nausea, allergic reactions, pruritus, raised liver enzymes, alopecia and dry mouth, bone marrow depression.

Caution with liver impairments.

Patients being treated for neurocysticercosis should receive appropriate steroid and anticonvulsant therapy as required. Oral or intravenous corticosteroids should be considered to prevent cerebral hypertensive episodes during the first week of anticysticeral therapy.

Pre-existing neurocysticercosis may also be uncovered in patients treated with albendazole for other conditions. Patients

1. Monitor blood counts and liver function.2. Administer within 7 days of start of normal menstruation in women of childbearing age.3. Adequate nonhormonal contraceptive measures must be taken during and for 1 mth after therapy.4.Perform liver function tests and blood counts before and every 2 wk during high dose therapy of hydatid disease.

Classification Contraindication Side EffectsFunctional:Antihelmenthic

Chemical: benzimidazole derivative agents

Contraindicated with hypersensitivity to albendazole, pregnancy, neonates, lactating mothers, and liver impairment

dizziness

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may experience neurological symptoms (e.g. seizures, increased intracranial pressure and focal signs) as a result of an inflammatory reaction caused by death of the parasite within the brain. Symptoms may occur soon after treatment; appropriate steroid and anticonvulsant therapy should be started immediately.

Cysticercosis may, in rare cases, involve the retina. Before initiating therapy for neurocysticercosis, the patient should be examined for the presence of retinal lesions. If such lesions are visualized, the need for anticysticeral therapy should be weighed against the possibility of retinal damage caused by albendazole-induced changes to the retinal lesion.

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Clinical Instructor: ______Zanita Glenda A. Plaga, RN___ Reference: MIMS Philippines. Retrieved from: http://mims.com/Philippines/drug/info/albendazole/?q=albendazole&type=brief&mtype=generic

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WEST VISAYAS STATE UNIVERSITYCOLLEGE OF NURSING

La Paz, Iloilo City

DRUG STUDY

Name of Patient: ___________________mother________________ Bed/ Ward No.: __________________ Attending Physician: ________________________________________Age: ________________ Impression/ Diagnosis: _____________________________________

Name of Drug Dosage, Route, Frequency and

Timing

Mechanism of Action

Indication Adverse Reaction Special Precaution Nursing Responsibilities

Generic:Levonorgestrel + ethinylestradiol

Brand:Mycrogynon

Dosage:

Route:PO

Frequency:OD

Timing:

Combination of hormonal contraceptives inhibits ovulation by modulating pituitary secretion of gonadotrophins, luteinising hormone and follicle stimulating hormone through a negative feedback system. They reduce sperm penetration if ovulation does occur by altering the cervical mucus; cause changes in the endometrium which reduce the risk of nidation and may change the tubal transport of the ova through the fallopian tubes.

Contracetpion Menstrual irregularities; headache, dizziness; breast discomfort; gynaecomastia; depression; disturbance of appetite; wt changes; fluid retention; oedema; changes in libido; hair loss or hirsutism; GI disturbances (nausea and vomiting); genitourinary changes; haematologic disorders; endocrine and metabolic disorders; cholestatic jaundice; local skin reactions; chorea; contact lens intolerance; steeping of corneal curvature; pulmonary thromboembolism; carbohydrate and/or glucose intolerance;

Sex-steroid dependent cancer; past ectopic pregnancy; malabsorption syndromes; functional ovarian cysts; active liver disease, recurrent cholestatic jaundice, history of jaundice in pregnancy; history of CV or renal impairment; DM; asthma; epilepsy; migraine; depression; lactation; conditions exacerbated by fluid retention; hypercalcaemia; CV and gall bladder diseases; lipid effects; familial defects of lipoprotein metabolism; patients

1. Counsel clients about the indication of the drug and the drug are not indicated for preventing or curing HIV or AIDS.

2. Monitor blood glucose concentrations in patients with diabetes. Closely monitor patients on long-term corticosteroids and diabetic patients on insulin for infection.

3. Drug is excreted in breast milk.

4. Levonorgestrel (oral) is not recommended for routine use as a contraceptive.

5. Instruct patients to take

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Absorption: Absorbed by GI tract. Bioavailability: ethinyl estradiol: 38-48%; levonorgestrel: 100%.Distribution: Distribution: Ethinyl estradiol: 4.3 L/kg; Levonorgestrel: 1.8 L/kg. Protein binding: Ethinyl estradiol: 95-97%; Levonorgestrel: 97-99% bind to sex hormone-binding globulin and albumin.Metabolism: Slowly metabolised. Estradiol: hepatic via oxidation and conjugation in GI tract; hydroxylated via CYP3A4 to metabolites; first-pass effect; enterohepatic recirculation; reversibly converted to estrone and estriol. Levonorgestrel: hepatic involving CYP3A4; undergoes reduction and conjugation followed

depression; chloasma; BP increase, liver impairment; reduced menstrual loss, 'spotting' in early cycles, absence of withdrawal bleeding; rarely photosensitivity; increased risk in breast cancer; elevation of plasma bound iodine, cortisol and thyroid binding, erythrocyte sedimentation may be accelerated; increases in plasma copper, iron and alkaline phosphatase; may affect serum triglyceride and lipoprotein levels; retinal vascular thrombosis.Potentially Fatal: Hepatic tumours; increased risk of thromboembolism.

at risk of venous thromboembolism, breast cancer, preexisting uterine leiomyomata and benign hepatic adenoma; family history of arterial disease in 1st degree relative <45 yr; BP > systolic 140 mmHg and diastolic 90 mmHg; >35 yr; BMI 30-39 kg/m2; migraine without focal aura, controlled with 5HT1; GI upset (vomiting and diarrhoea), missed pills and interaction with other drugs may require additional contraceptive precautions. Should be taken at same time each day.

levonorgestrel emergency contraceptive as soon as possible and not more than 72 h after unprotected intercourse or known or suspected contraceptive failure.

6. Monitor VS of client.

7. Recheck name of drug and expiration date

8. Tell patient to report to health care provider immediately if adverse effect occurs.

Classification Contraindication Side Effects8

by hydroxylation; forms metabolites.Excretion: Half life elimination: estradiol: 12-23 hr; levonorgestrel: 22-49 hr. Excretion: levonorgestrel: urine (40-68% parent drug and metabolites) and faeces (16-48% as metabolites); estradiol: through urine as metabolites estrone and estriol, also through faeces in small quantities as glucuronide and sulphate conjugates.

Functional:Cotraceptive

Chemical:Progesterone;Emergency contraceptive

Pregnancy, undiagnosed vaginal bleeding, severe arterial disease (or family history of atherogenic lipid profile); liver adenoma; porphyria; after evacuation of hydatidiform mole; history of breast cancer; hepatic impairment; thrombophloebitis or thromboembolic disorders; breast carcinoma except in selected patients being treated for metastatic disease; oestrogen-dependent tumour; smoking ≥40 cigarettes daily; >50 yr; diabetes complications present; BMI >39 kg/m2; migraine with typical focal aura, lasting >72 hr despite treatment or migraine treated with ergot derivatives; BP >160 mmHg systolic and 100 mmHg diastolic; transient ischaemic

Acne, hypertension, abdominal pain, nausea, vomiting and diarrhea,vaginitis, dysmenorrhea, breast pain, abnormal pap smear and decreased libido, weight gain and fatigue, back pain

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attacks without headaches; SLE; gallstones; history of haemolytic uraemic syndrome, pruritis during pregnancy; cholestatic jaundice; chorea or deterioration of otosclerosis pemphigoid; breast feeding during 1st 6 mth after delivery.

Clinical Instructor: ______Zanita Glenda A. Plaga, RN______ Reference: MIMS.COM

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References:

MIMS.com

http://www.drugs.com/pregnancy/levonorgestrel.html

http://medical-dictionary.thefreedictionary.com/levonorgestrel

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