CHM 500 Course Proposal April 2010

8/13/2019 CHM 500 Course Proposal April 2010

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CHM 500 The Responsible Conduct of Research in Chemistry

6 weeks; 2.5 hours per week

Grading: PDF

Students will discuss and evaluate the role that professional researchers have in dealingwith reporting of research, responsible authorship, animal studies, human studies,

misconduct and fraud in science, professionalism in scientific relationships, and

intellectual property. Successful completion is based on attendance, reading, and activeparticipation in the discussion sessions. Students are expected to read the materials prior

to attending each course. This course is designed to satisfy the requirements of federal

funding agencies for training research scientists in the ethical practice of science.

Lecturer: Michael Kelly, Ph.D.

Syllabus

Week 1: Research Integrity and Scientific Practice

Week 2: Mentorship, Personal Behavior, and Conflict of Interest

Week 3: Communication of Research and Research Misconduct

Week 4: Collaborative Research and Intellectual Property, Export Control

Week 5: Animal and Human Subjects

Week 6: Science and Society


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Week 1: Research Integrity and Scientific Practice

What is the ethical and moral framework that guides the practice of research today?

What do we owe others?

Reading:

University Plan for Training in Responsible Conduct of Research

http://www.princeton.edu/orpa/documents/RCR_Plan_2010_Final.pdf

Scientists behaving badly,Nature2005

On Being A Scientist: Responsible Conduct In Research

http://www.nap.edu/openbook.php?record_id=4917&page=R1

The Chemical Professionals Code of Conduct

http://portal.acs.org/portal/acs/corg/content?_nfpb=true&_pageLabel=PP_ARTICLEMAIN&node_id=1095&content_id=CTP_004007&use_sec=true&sec_url_var=region1

What is Ethics in Research & Why is It Important? by David B. Resnik, J.D., Ph.D.

http://www.niehs.nih.gov/research/resources/bioethics/whatis.cfm

Research Timeline of bioethics

http://www.niehs.nih.gov/research/resources/bioethics/timeline.cfm


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Week 2: Mentorship, Personal Behavior, and Conflict of Interest

How do you choose an advisor? What are the responsibilities that mentors have to their

trainees? What are the responsibilities that trainees have to their mentors? This week we

will discuss a variety of mentoring, teaching and learning related ethical dilemmas.

These will include ethical approaches to teaching, collaborative relationships, integrity inthe learning process, responsibilities and rights of research assistants, and the role of the

mentor.

Reading:

Postdoctoral Fellows and Mentorshttp://www.aamc.org/research/postdoccompact/postdoccompact.pdf

A Guide to Training and Mentoring in the Intramural Research Program at NIH

http://www1.od.nih.gov/oir/sourcebook/ethic-conduct/mentor-guide.htm

Mentor Expectations and Student Responsibilities in Undergraduate Research

http://www.cur.org/conferences/responsibility/Monte.pdf

Mentoring the Mentors: The Yoda Factor in Promoting Scientific Integrity

http://muse.jhu.edu/journals/american_journal_of_bioethics/v002/2.4motta.pdf

RCR Mentoring: The Responsible Mentoring of Research

http://ccnmtl.columbia.edu/projects/rcr/rcr_mentoring/foundation/index.html

Princeton Conflict of Interest in Research Policy


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Week 3: Research Misconduct and the Communication of Research

What is research misconduct? What are plagiarism, fraud, fabrication, and falsification?

What is data selection? Can you use Photoshop to prepare images for publication?

Research communications in the form of seminars, posters, or publications are primaryresults of research. How do you decide what to publish, when to publish, and who should

receive authorship? What is the responsibility to make scientific articles or data available

to the public? How does the peer review process work?

Reading:

Baltimore Casehttp://en.wikipedia.org/wiki/David_Baltimore

Cold fusion

http://en.wikipedia.org/wiki/Cold_fusion

NIH peer review, Jan 2006

NIH Peer Review, Spring 2008

Misconduct of others Prevention Techniques for ResearchersAPS observer

Taking on the cheats,Nature2005CSI: cell biology,Nature2005

ACS Ethical Guidelines for Publishing

Council of Science Editors: White paper on Promoting Integrity in Scientific Journal

Publications

Journals Find Fakery in Many Images Submitted to Support Research

http://chronicle.com/free/2008/05/3028n.htm


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Week 5: Animal and Human Subjects

What are the ethical issues in laboratory animal research? How do researchers justify the

utilization of animals to gain knowledge? What is the Animal Welfare Act? What

mechanisms of oversight govern animal experimentation?

What is bioethics? How do researchers safeguard human subjects in research?

Reading:

Princeton University IACUC general policy

Princeton University Institutional Review Panel for Human Subjects

Institutional Policies and Responsibilities


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Week 6: Science and Society

Why is basic research funded? What is the level of public versus private funding? Who

sets the priorities for research funding? What are the public perceptions of the scientific

enterprise? What are the political and economic factors that affect scientific research?

Reading:

Browse the website for the Office of Science and Technology Policyhttp://www.ostp.gov/

FY 2009 Administration Research and Development Budget Prioritieshttp://www.ostp.gov/galleries/Budget09/FY2009FINALOMB-

OSTPRDPriorityMemo.pdf

Science Advisors Says that Pruning is Key to a Healthy Budget

http://www.sciencemag.org/cgi/reprint/315/5814/927.pdf

Browse NIH Websitehttp://grants.nih.gov/grants/oer.htm

A Timely Harvest,Nature2007

Of power maniacs and unethical geniuses: science

and scientists in fiction film, Public Understand. Sci. 2003

Gods formula and Devils contribution: Science in the press, Public Understand. Sci.2003

CHM 500 Course Proposal April 2010

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