Chiral Diols: A New Class of Additives for Direct Aldol Reaction Catalyzed by L-Proline.

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2007 Alcohols Q 0230 Chiral Diols: A New Class of Additives for Direct Aldol Reaction Catalyzed by L-Proline. — It is found that efficiency and enantioselectivity of the reaction can be improved by addition of small amounts of chiral diols. Best results are obtained in the presence of L-proline and (S)-BINOL. — (ZHOU, Y.; SHAN*, Z.; J. Org. Chem. 71 (2006) 25, 9510-9512; Dep. Chem., Wuhan Univ., Wuhan 430072, Hubei, Peop. Rep. China; Eng.) — Jannicke 16- 069

Transcript of Chiral Diols: A New Class of Additives for Direct Aldol Reaction Catalyzed by L-Proline.

Page 1: Chiral Diols: A New Class of Additives for Direct Aldol Reaction Catalyzed by L-Proline.

2007

AlcoholsQ 0230 Chiral Diols: A New Class of Additives for Direct Aldol Reaction Catalyzed by

L-Proline. — It is found that efficiency and enantioselectivity of the reaction can be improved by addition of small amounts of chiral diols. Best results are obtained in the presence of L-proline and (S)-BINOL. — (ZHOU, Y.; SHAN*, Z.; J. Org. Chem. 71 (2006) 25, 9510-9512; Dep. Chem., Wuhan Univ., Wuhan 430072, Hubei, Peop. Rep. China; Eng.) — Jannicke

16- 069

K-FLEX Urethane Diols - King Industries · K-FLEX® Urethane Diols are low molecular weight (MW) diols with an aliphatic urethane backbone and a narrow MW distribution. They allow

K-FLEX Urethane Diols - King Industries · K-FLEX® Urethane Diols are low molecular weight (MW) diols with an aliphatic urethane backbone and a narrow MW distribution. They allow

Aldol and Claisen Condensations

Aldol and Claisen Condensations

ORGANIC LETTERS Total Synthesis of LFA-1 Antagonist BIRT-377 … · 2014. 5. 6. · Recently, proline- and proline derivative-catalyzed asym-metric aldol,7 Mannich,8 Michael,9 Diels-Alder,10

ORGANIC LETTERS Total Synthesis of LFA-1 Antagonist BIRT-377 … · 2014. 5. 6. · Recently, proline- and proline derivative-catalyzed asym-metric aldol,7 Mannich,8 Michael,9 Diels-Alder,10

Chapter 15 Alcohols, Diols, and Thiols

Chapter 15 Alcohols, Diols, and Thiols

PROLINE CATALYZED ALDOL, MANNICH, AND MICHAEL …Sanyal.pdf · proline catalyzed aldol, mannich, and michael reactions: application of asymmetric organocatalysis sanjit sanyal department

PROLINE CATALYZED ALDOL, MANNICH, AND MICHAEL …Sanyal.pdf · proline catalyzed aldol, mannich, and michael reactions: application of asymmetric organocatalysis sanjit sanyal department

Mechanism of MOF-505 and Cu-ZSM-5 Promoted Mukaiyama Aldol ... · The Mukaiyama aldol reaction, an acid-catalyzed aldol reaction between a silyl enol ether and a carbonyl compound,

Mechanism of MOF-505 and Cu-ZSM-5 Promoted Mukaiyama Aldol ... · The Mukaiyama aldol reaction, an acid-catalyzed aldol reaction between a silyl enol ether and a carbonyl compound,

Aldehydes and Ketones : Aldol Reactions...Aldol addition products undergo retro-aldol reactions in the presence of strong base Chapter 17 17 ... Nitroalkane anions can undergo aldol-like

Aldehydes and Ketones : Aldol Reactions...Aldol addition products undergo retro-aldol reactions in the presence of strong base Chapter 17 17 ... Nitroalkane anions can undergo aldol-like

Diastereoselectivity (Enantioselectivity) of Aldol ...gmwgroup.harvard.edu/pubs/pdf/374.pdf · Diastereoselectivity (Enantioselectivity) of Aldol Condensations ... phosphates-mimics

Diastereoselectivity (Enantioselectivity) of Aldol ...gmwgroup.harvard.edu/pubs/pdf/374.pdf · Diastereoselectivity (Enantioselectivity) of Aldol Condensations ... phosphates-mimics

K-FLEX Urethane Diols - Specialty Additives | King …® Urethane Diols are low molecular weight (MW) diols with an aliphatic urethane backbone and a narrow MW distribution. They allow

K-FLEX Urethane Diols - Specialty Additives | King …® Urethane Diols are low molecular weight (MW) diols with an aliphatic urethane backbone and a narrow MW distribution. They allow

15 stereoselective aldol

15 stereoselective aldol

1)oxidation of alkenes to diols

1)oxidation of alkenes to diols

ALDOL CONDENSATION WITH 2,5-DIKETOPIPERAZINES

ALDOL CONDENSATION WITH 2,5-DIKETOPIPERAZINES

Crossed Aldol Condensations

Crossed Aldol Condensations

HPTU-50N HPTU-80N PROLINE MASTER PROLINE XE … · ProLine® 40-Gallon GCR-40 ProLine® 50-Gallon GCG-50 ProLine® ™ High Recovery 74-Gallon FCG-75 ProLine® Master Gas 50-Gallon

HPTU-50N HPTU-80N PROLINE MASTER PROLINE XE … · ProLine® 40-Gallon GCR-40 ProLine® 50-Gallon GCG-50 ProLine® ™ High Recovery 74-Gallon FCG-75 ProLine® Master Gas 50-Gallon

Carbonyl condensation reactions...Carbonyl condensation reactions. Aldol reaction: step 1. Aldol reaction: step 2. ... step 2. Intramolecular aldol reaction With 1,4-dicarbonyl compounds.

Carbonyl condensation reactions...Carbonyl condensation reactions. Aldol reaction: step 1. Aldol reaction: step 2. ... step 2. Intramolecular aldol reaction With 1,4-dicarbonyl compounds.

CONDENSATION CARBONYL CONDENSATION REACTIONS. CARBONYL CONDENSATION REACTIONS Aldol Reaction Dehydration of Aldol Products Intramolecular Aldol Reaction.

CONDENSATION CARBONYL CONDENSATION REACTIONS. CARBONYL CONDENSATION REACTIONS Aldol Reaction Dehydration of Aldol Products Intramolecular Aldol Reaction.

14.3 Aldol Reaction and Claisen Condensation in Biology Enol – Keto Tautomerization Aldol Reaction Claisen Condensation Main Menu.

14.3 Aldol Reaction and Claisen Condensation in Biology Enol – Keto Tautomerization Aldol Reaction Claisen Condensation Main Menu.

Direct synthesis of polycarbonate diols from atmospheric ...

Direct synthesis of polycarbonate diols from atmospheric ...

PROLINE CATALYZED ALDOL, MANNICH, AND … · proline catalyzed aldol, mannich, and michael reactions: application of asymmetric organocatalysis sanjit sanyal department of chemistry

PROLINE CATALYZED ALDOL, MANNICH, AND … · proline catalyzed aldol, mannich, and michael reactions: application of asymmetric organocatalysis sanjit sanyal department of chemistry

Aldol Reaction Time-Linechemlabs.princeton.edu/.../sites/6/Northrup_aldol.pdf2 Racemic Aldol Technology Aldol Reaction Discovered Independently By Charles Adolphe Wurtz in Germany

Aldol Reaction Time-Linechemlabs.princeton.edu/.../sites/6/Northrup_aldol.pdf2 Racemic Aldol Technology Aldol Reaction Discovered Independently By Charles Adolphe Wurtz in Germany