ChemInform Abstract: Novel Approach for the Synthesis of...

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ChemInform 2012, 43, issue 02 © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim Fused pyrimidine derivatives R 0515 DOI: 10.1002/chin.201202170 Novel Approach for the Synthesis of N-Substituted-4-(2-methyl-4-oxo-4H-quin- azolin-3-yl)-butyramides. — The direct amide formation from acid (III) in the pres- ence of a common coupling reagent (EDC/HOBt) fails but succeeds using easily acces- sible phosphazo compounds (IV). — (AMIR*, M.; ALI, I.; Synth. Commun. 41 (2011) 14, 2086-2095, http://dx.doi.org/10.1080/00397911.2010.497594 ; Dep. Pharm. Chem., Hamdard Univ., New Delhi 110 062, India; Eng.) — H. Haber 02- 170

Transcript of ChemInform Abstract: Novel Approach for the Synthesis of...

Fused pyrimidine derivativesR 0515 DOI: 10.1002/chin.201202170

Novel Approach for the Synthesis of N-Substituted-4-(2-methyl-4-oxo-4H-quin-azolin-3-yl)-butyramides. — The direct amide formation from acid (III) in the pres-ence of a common coupling reagent (EDC/HOBt) fails but succeeds using easily acces-sible phosphazo compounds (IV). — (AMIR*, M.; ALI, I.; Synth. Commun. 41 (2011) 14, 2086-2095, http://dx.doi.org/10.1080/00397911.2010.497594 ; Dep. Pharm. Chem., Hamdard Univ., New Delhi 110 062, India; Eng.) — H. Haber

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ChemInform 2012, 43, issue 02 © 2012 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim