ChemInform Abstract: K2CO3-Assisted One-Pot Sequential Synthesis of...

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ChemInform 2010, 41, issue 51 © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim www.cheminform.wiley-vch.de Pyridine derivatives R 0380 DOI: 10.1002/chin.201051136 K 2 CO 3 -Assisted One-Pot Sequential Synthesis of 2-Trifluoromethyl-6-difluoro- methylpyridine-3,5-dicarboxylates under Solvent-Free Conditions. — Hantzsch reaction of ethyl trifluoroacetate at high temperature affords the synthetically and phar- maceutically important polysubstituted pyridines (III) as single products. — (SHEN, L.; CAO*, S.; WU, J.; LI, H.; ZHANG, J.; WU, M.; QIAN, X.; Tetrahedron Lett. 51 (2010) 37, 4866-4869, DOI:10.1016/j.tetlet.2010.07.041 ; Shanghai Key Lab. Chem. Biol., East China Univ. Sci. Technol., Shanghai 200237, Peop. Rep. China; Eng.) — Mais 51- 136

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Page 1: ChemInform Abstract: K2CO3-Assisted One-Pot Sequential Synthesis of 2-Trifluoromethyl-6-difluoromethylpyridine-3,5-dicarboxylates under Solvent-Free Conditions.

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Pyridine derivativesR 0380 DOI: 10.1002/chin.201051136

K2CO3-Assisted One-Pot Sequential Synthesis of 2-Trifluoromethyl-6-difluoro-methylpyridine-3,5-dicarboxylates under Solvent-Free Conditions. — Hantzsch reaction of ethyl trifluoroacetate at high temperature affords the synthetically and phar-maceutically important polysubstituted pyridines (III) as single products. — (SHEN, L.; CAO*, S.; WU, J.; LI, H.; ZHANG, J.; WU, M.; QIAN, X.; Tetrahedron Lett. 51 (2010) 37, 4866-4869, DOI:10.1016/j.tetlet.2010.07.041 ; Shanghai Key Lab. Chem. Biol., East China Univ. Sci. Technol., Shanghai 200237, Peop. Rep. China; Eng.) — Mais

51- 136

ChemInform 2010, 41, issue 51 © 2010 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim