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AntibioticsU 1200 Application of Tandem Ring-Closing Enyne Metathesis: Formal Total Synthesis

of (-)-Cochleamycin A. — The formal synthesis of the target (IV) is achieved by the preparation of its precursor (III) with a metathesis reaction of intermediate (I) as a key step. — (MUKHERJEE, S.; LEE*, D.; Org. Lett. 11 (2009) 13, 2916-2919; Dep. Chem., Univ. Ill., Chicago, IL 60607, USA; Eng.) — R. Steudel

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