ChemInform Abstract: A Novel Consecutive Three-Component Coupling—Addition—SNAr (CASNAR)...
-
Upload
benjamin-willy -
Category
Documents
-
view
214 -
download
0
Transcript of ChemInform Abstract: A Novel Consecutive Three-Component Coupling—Addition—SNAr (CASNAR)...
![Page 1: ChemInform Abstract: A Novel Consecutive Three-Component Coupling—Addition—SNAr (CASNAR) Synthesis of 4H-Thiochromen-4-ones.](https://reader030.fdocuments.us/reader030/viewer/2022020508/575003d51a28ab11489b57e1/html5/thumbnails/1.jpg)
www.cheminform.wiley-vch.de
Thiopyran derivativesR 0370 A Novel Consecutive Three-Component Coupling—Addition—SNAr (CASNAR)
Synthesis of 4H-Thiochromen-4-ones. — The one-pot procedure provides a conve-nient access to the title compounds via coupling of hetaryl chlorides with alkynes under modified Sonogashira conditions followed by addition of sodium sulfide and intramo-lecular SNAr reaction. Furthermore, the method is applied to the synthesis of thiopyra-nopyridiones (XI). — (WILLY, B.; MUELLER*, T. J. J.; Synlett 2009, 8, 1255-1260; Inst. Org. Chem. Makromol. Chem., Heinrich-Heine-Univ., D-40225 Duesseldorf, Germany; Eng.) — Mais
40- 125
ChemInform 2009, 40, issue 40 © 2009 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim