ChemInform Abstract: 10-Phenylbutyryl-substituted Anthracenones as Inhibitors of Keratinocyte Growth...
1
2001 anthracene derivatives anthracene derivatives Q 1080 35 - 110 10-Phenylbutyryl-substituted Anthracenones as Inhibitors of Ker- atinocyte Growth and LTB 4 Biosynthesis. — Twelve compounds of type (III), (V), (VII), and (IX) are prepared and tested as inhibitors of leukotriene B 4 (LTB 4 ) biosynthesis. Compounds (III) and (IX) show inhibitory activity against LTB 4 biosynthesis. Their anti-proliferative activity is compa- rable to that of the known antipsoriatic anthralin. — (MUELLER, KLAUS; BREU, KLAUS; REINDL, HANS; Eur. J. Med. Chem. 36 (2001) 2, 179-184; Inst. Pharm. Chem., Westfael. Wilhelms-Univ., D-48149 Muenster, Germany; EN) 1
-
Upload
klaus-mueller -
Category
Documents
-
view
212 -
download
0
Transcript of ChemInform Abstract: 10-Phenylbutyryl-substituted Anthracenones as Inhibitors of Keratinocyte Growth...
![Page 1: ChemInform Abstract: 10-Phenylbutyryl-substituted Anthracenones as Inhibitors of Keratinocyte Growth and LTB4 Biosynthesis.](https://reader031.fdocuments.us/reader031/viewer/2022020508/575003801a28ab1148997fba/html5/thumbnails/1.jpg)
2001 anthracene derivatives
anthracene derivativesQ 1080
35 - 11010-Phenylbutyryl-substituted Anthracenones as Inhibitors of Ker-atinocyte Growth and LTB4 Biosynthesis. — Twelve compoundsof type (III), (V), (VII), and (IX) are prepared and tested as inhibitors ofleukotriene B4 (LTB4) biosynthesis. Compounds (III) and (IX) show inhibitoryactivity against LTB4 biosynthesis. Their anti-proliferative activity is compa-rable to that of the known antipsoriatic anthralin. — (MUELLER, KLAUS;BREU, KLAUS; REINDL, HANS; Eur. J. Med. Chem. 36 (2001) 2, 179-184;Inst. Pharm. Chem., Westfael. Wilhelms-Univ., D-48149 Muenster, Germany;EN)
1