Syllabus Chemistry 140B

Summer 2013

INSTRUCTOR: Dr. Haim Weizman, E-mail: hweizman@ucsd.edu LECTURE HOURS: M, Tu, W, Th, 3:30 – 4:50, SOLIS 107 OFFICE HOURS: Tu, Th 12:00-1:00 pm, or by appointment, Urey 2254. Please check the course web site for possible changes TAS DISCUSSION SESSIONS: M, Tu, W, Th 2:00 – 2:50, SOLIS 107 PROBLEM SOLVING SESSION: W 5:00 – 5:50, PETER 110 COURSE WEB PAGE: http://ted.ucsd.edu All material will be distributed

electronically. REQUIRED TEXT: Organic Chemistry, 10th by T. W. Graham Solomons and Craig B. Fryhle,

John Wiley & Sons The text is most important for problems and for clarification of points from lecture. Lecture will often clarify and expand upon material covered in the text. SUGGESTED TEXT:

Organic Chemistry, Student Study Guide and Student Solutions Manual, 10th by T. W. Graham Solomons and Craig B. Fryhle, John Wiley & Sons. Several other organic texts are available in the Science and Engineering Library. Use them when you desire additional reading or problems. You are strongly advised to stay ahead of the lectures in your reading! MOLECULAR MODELS: A personal set of molecular models is highly recommended. Models are particularly important for the understanding of stereochemical relationships and 3-dimensional structures. Various types are available. Models are not to be used on exams. TEACHING ASSISTANTS: Excellent teaching assistant will be working with me on this course. You can schedule additional appointments with your TA. Kristina Hamill khamill@ucsd.edu Patrycja Hopkins phopkins@ucsd.edu DISCUSSION SESSIONS: Attending discussion sessions is not mandatory but will facilitate learning through active interactions with the TA and your peers. During each session you will be given a handout with problems.

EXAMINATION AND GRADING: The course will have one midterm and a comprehensive final. Be prepared to show a picture ID at all exams. Exams will be given only at the scheduled times. Make-up exams are not a possibility.

The total points for this course are as follows:

Midterm 100 points Final 200 points Total 300 points

Regrading policy: Carefully check the grading on your examination after it is returned to you. Make no new marks on the exam! If there is an error, return the exam to me with a note indicating the error. If you feel a question has been improperly graded, return the test to me and I will regrade the entire exam. You may use either pencil or pen for the examinations. However, examinations taken in pencil will not be eligible for regrades. Be aware that when you request a regrade of an exam, the entire exam will be regraded and your score for that exam may go up or down! Exam scores will be considered final three days after the exams are returned to the class.

ACADEMIC HONESTY: Please be aware of the UCSD policy on Integrity of Scholarship. Copying, discussing material or using reference material during an examination is cheating. Any student found cheating on an examination will receive a "0" on that examination and a letter explaining the reasons for this grade will be sent to the appropriate University officials for additional disciplinary action. Taking an examination for someone else or having someone else take an examination for you is a very serious offense for which expulsion from the University will be urged. Changing an answer on an exam that has been returned to you and then requesting a regrade is also a very serious offense. Remember that you may not drop or withdraw from a course while a dishonesty case is pending, or if found guilty. Any student who is found guilty of academic dishonesty will receive an F.

Tentative Course Schedule

Date Topic Chapter Week 1 Nuclear Magnetic Resonance spectroscopy 9 Radical Reactions 10 Week 2 Alcohols and Ethers 11

Conjugated systems 13 Week 3 Aromatic compounds 14

Reactions of aromatic compounds 15 7/18/131 (Th) Midterm Week 4 Aldehydes and Ketones 12

Aldehydes and Ketones 16 Week 5 Aldehydes and Ketones 16

Carboxylic acids and their derivatives 17 Final Examination2 (comprehensive) 9-17

1 Midterm during lecture time. 2 Final: 8/2/13 3:00-6:00 pm. Location(s) to be announced.

General Advice and Comments

Chemistry 140B is the second quarter of a three-quarter survey of organic chemistry. Organic chemistry is a part of our everyday life and it contributes to make our life easier, healthier and happy. Understanding the fundamentals of organic chemistry is crucial to revealing the secrets of biological systems In this quarter we will study methods for identifying molecular structure as well as more reactions. This will set the foundations for planning a complex synthesis.. How to do well in the course? Organic Chemistry is a rational subject and can be rigorously understood. Although it may have worked for you in other classes, memorization is NOT the right way to study organic chemistry. Certain facts have to be learned and recognized, of course, but understanding fundamental principles, general mechanisms and reactivity patterns is a much more effective approach to studying organic chemistry. Although inherently not more difficult than other physical sciences, organic chemistry may appear different as a large amount of new conceptual material needs to be assimilated. Organic chemistry classes are highly cumulative and ideas introduced early on will be used to develop other concepts later. Thus, letting things slide is unwise, as the material begins to accumulate relentlessly. Waiting until a few days before an exam to begin learning the material is therefore a serious mistake. Continuous learning and constant practicing is a key for success. Do not fall behind. Practice, practice, practice.. I cannot overemphasize the importance of solving problems and writing mechanisms in this course. Simply listening to lecture and reading your text is not enough. Sometimes it is very easy to convince yourself that you understand the material. Yet, solving problems is the best way to exercise and secure new concepts. Challenge yourself and enjoy putting the puzzles together. Try studying with a partner or in groups. You will be astonished at the insight that you gain when you hear another opinion or when you have to explain something to others. Seeking help and advice from the instructors can make a huge difference. It seems too few students take advantage of this opportunity. Do not hesitate to come regularly to office hours. This time is set aside for this purpose! When you encounter a problem, however, first attempt to solve it yourself. If it persists, talk to your TA or me. I wish that this journey will be scientifically stimulating and enjoyable for you.

Haim Weizman