8/23/2019 CHEM 2 Ch 31 Review Questions

1/2

CH 31Chemistry quiz bank

1) Tumor markers may be defined as:a) Biologic substances synthesized and released by cancer cells or substances produced by the host

in response to cancer cells*

b) None of thesec) Analytic tests ( e.g. immunoassays) used to mark cancerous cellsd) Radioactive substances and chemicals used to help the physician identify cancer cells

2) The most common immunoassays used to measure PSA detect which form of the enzyme?a) Total PSA*b) PSA complexed with alpha-q antichymotrypsinc) Free PSAd) PSA complexed with alpha2-macroglobulin

3) What percentage of women will have invasive cancer at some time in their life?a) 25%b) 33%*c) 50%d) 75%

4) Which of the following is an Oncofetal antigen?a) Prostate-specific antigenb) CA-125c) Alpha-fetoprotein*d) Beta-hCG

5) A tumor marker used in the assessment of choriocarcinoma or hydatidiform mole isa) Beta-hCG*b) IgGc) AFPd) CEA

6) The major clinical use for CA-125 is monitoring treatment response ofa) Breast cancerb) Prostatic cancerc) Ovarian carcinoma*d) Colorectal cancer

7) A serum PSA is used for all of the following excepta) Screeningb) Diagnosis*c) Detecting recurrenced) Monitoring response

8) What are the major limitations of tumor markers?a) Turnaround timeb) Costc) Sensitivity and specificity*d) Imprecision

9) Which of the following enzymes is commonly used as a tumor marker?

8/23/2019 CHEM 2 Ch 31 Review Questions

2/2

CH 31Chemistry quiz bank

a) Lipaseb) Aldolasec) Catalased) LD*

10)Tumor marker tests are used toa) All of these*b) Detect recurrent diseasec) Monitor response to therapyd) Aid in staging of cancer