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    Phrenology

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    (Taken from Kalat, 2007, p. 83)

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    Nervous System

    Central nervous system(CNS) Brain and Spinal Cord

    Peripheral

    (blue in figure) Cranial nerves, spinal

    nerves, peripheral receptororgans

    Autonomic (red in figure)

    Control of visceral funcion

    Sympathetic

    Parasympathetic

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    CNS

    Two Cerebral hemispheresTwo Cerebral hemispheres

    The brain stemDiencephalonDiencephalon

    Mesencephalon (midbrain)Pons

    Medulla Oblongata

    Cerebellum

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    Brain is protected by:

    Skull Meninges

    Cerebrospinal fluid (CSF)

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    Meninges

    Three layers

    Dura mater Arachnoid

    Pia mater

    Diagrammatic representation of a section across the top of the

    skull, showing the membranes of the brain, etc. (Greys769 Taken

    from on-line Grays Anatomy; Modified from Testut.)

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    Dura Mater (hard mother)

    Continuous with the dura mater that covers the spinal

    cord Tough, fibrous connective tissue Two layer

    Superficial (outer) periosteal layer adheres to the skull Deep (inner) meningeal layer is in contact with the arachnoidmater

    Meningeal veinscourse through the dura Dura punctured by Bridging veinsdrain underlying

    neural tissue into sinuses Dural veinous sinusesform between layers

    Drain blood and CSF and empty into jugular vein

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    Three major reflections Between the cerebral

    hemispheres Falx cerebri

    Between the cerebellum and

    the occipital lobe Tentorium cerebelli

    Underneath the cerebral

    hemispheres Falx cerebelli

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    Arachnoid Mater

    Spider-web likenonvascular membrane

    In contact with the duramater above it, and theCSF-filled subarachnoid

    cavity is below it.(subarachnoid cavityis filled with delicatearachnoid fibers

    extending down to the piamater)

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    Arachnoid granulations

    protuberances (villi)through the meningeallayer of the dura

    Locations of transfer ofsubarachnoid CSF toveneous system

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    Pia Mater

    Thin translucent layer

    Adheres to the brain surface Location of the brain blood vessels

    Together with the arachnoid are called the

    pia-arachnoid membrane

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    Epidural space (skull and dura mater)

    Rupture of middle menigeal artery, or accumulation of arterialblood in the epidural space, is life-threatening

    Subdural space (dura mater and arachnoid) Rupture of bridging veins, leading to subdural hemorrhage, or

    accumulation of blood in space requires surgical intervention

    Subarachnoid space (arachnoid and pia mater) Contains CSF and cerebral blood vessels Rupture of these vessels leads to subarachnoid hemorrhage

    Condition may be due to Trauma

    Congenital abnormalities (aneurysms) High Blood Pressure

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    Cerebral Dural Venous Sinuses

    Endothelial-lined channels, devoidof valves

    located between the periosteal andmeningeal layers of the dura mater

    Low-pressure return channels forvenous blood back to circulatorysystem

    Superior Saggital Sinus

    Inferior Saggital Sinus

    Vein of Galen

    Straight Sinus

    InternalCerebral vein

    Confluence ofSinuses(torcular

    Herophili)

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    Cerebral Dural Venous Sinuses

    Confluence ofSinuses

    Transverse Sinus

    Sigmoid Sinus

    Jugular vein

    SuperiorPetrosal Sinus

    InferiorPetrosal Sinus

    Occipital SinusMarginal

    sinusVeinous plexuses

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    Lateral Surface

    Principle landmarks

    Sylvian fissure

    Central sulcusdemarcate three of the four lobes

    Parieto-occipital sulcus -> pre-

    occipital notch demarcatesparietal and temporal lobedivisions from occipital lobe

    Insula lies within the SylvianFissure

    Temporal Lobe

    Frontal LobeParietal Lobe

    Occipital

    Lobe

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    Frontal Lobe

    Primary Motor Area Relatively low levels of

    stimulation ofprecentral gyrusproduce movement

    Lesions in this regionproduce contralateralparalysis.

    Most marked formuscles involved in finemotor movement

    Motor Homonculus

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    Frontal Lobe

    Premotor Motor Area

    Rostal of PrecentralSulcus

    Important in initiating

    motor plans andchanging motor plans

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    Frontal Lobe

    Brodmanns Area or

    Frontal Eye Fields Between superior andinferior frontal gyri

    Important for eyemovements

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    Frontal Lobe

    Brocas Area Bordered by the

    inferior frontal sulcusand anterior horizontalRamus

    In the left hemisphereis responsible forspeech

    Lesions in this arearesult in aphasia

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    Parietal Lobe

    Primary sensory area

    Delineated by thecentral and postcentralsulci

    Stimulation producestingling and numbness

    Similar contralateralrepresentation asprimary motor area.

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    Temporal Lobe

    Gyri ofHeschl

    Wernickesarea

    Perce

    ptionof

    color

    andform

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    Occipital Lobe

    Visio

    n

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    Medial Surface

    Corpus Collosum

    Fibers which connect

    the cerebralhemispheres

    Divided into:

    Rostrum (Head) Body

    Knee

    Splenium

    Lesion disconnects thehemispheres

    R

    B

    S

    G

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    AnteriorCommissure Fiber bundle

    Connects: temporal lobes

    olfactory structuresin each hemisphere

    In humans, anteriorlimb = olfactory

    posterior limb:visual and auditoryareas

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    Surgery to cut the corpus collosum produces Split-brainpatients

    Can perform familiar tasks bi-manually, but novel tasksare harder to coordinate Hands often work in opposition to one another.

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    Patient saw the word sky in the

    LVF and scraper in the RVF. With his right hand he drew what hecould see in his RVF (LH)

    With his left hand:

    Left hemisphere (LH) controlled itenough to draw a sky His RH controlled it enough to draw a

    scraper. Neither could combine the words to

    detect the emergent concept.

    Similarly, hot in the LVF and dogin the RVF produced a picture of anoverheating dog, not a weiner in abun.

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    Recovery

    Corpus collosum doesnot heal.

    Many alternative inter-hemispheric connectionsare present.

    Left hemisphere learns to

    control the right, butsubtle effects can still beobserved.

    Patients also learn

    strategies