Chapter 8 - INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/13755/16/16...References -271- Bae,...
Transcript of Chapter 8 - INFLIBNETshodhganga.inflibnet.ac.in/bitstream/10603/13755/16/16...References -271- Bae,...
Chapter 8
References
Abe, T., Sakane, M., Ikoma, T., Kobayashi, M., Nakamura, S., Ochiai, N. (2008)
Intraosseous delivery of paclitaxel-loaded hydroxyapatite-alginate composite
beads delaying paralysis caused by metastatic spine cancer in rats. J. Neurosurg.
Spine 9: 502-510.
Ahad, A., Aqil, M., Kohli, K., Sultana, Y., Mujeeb, M., Ali, A. (2012) Formulation and
optimization of nanotransfersomes using experimental design technique for
accentuated transdermal delivery of valsartan. Nanomed: Nanotechnol. 8(2):
237-249.
Ahmed, F., Pakunlu, R.I., Brannan, A., Bates, F., Minko, T., Discher, D.E. (2006)
Biodegradable polymersomes loaded with both paclitaxel and doxorubicin
permeate and shrink tumors, inducing apoptosis in proportion to accumulated
drug. J. Control. Release 116: 150-158.
Ali, A.I., Jitender, M., Dinesh, K., Satish, S., Shankar, P.R., Asgar, A. (2011)
Comparative study of transfersomes, liposomes, and niosomes for topical delivery
of 5-fluorouracil to skin cancer cells: preparation, characterization, in vitro
release, and cytotoxicity analysis. Anti-cancer drugs. 22(8): 774-782.
Allen, C., Maysinger, D., Eisenberg, A. (1999) Nano-engineering block copolymer
aggregates for drug delivery. Coll. Surf. B: Biointer. 16: 3-27.
Appendino, G. (1993) Taxol(R)
(paclitaxel): historical and ecological aspects. Fitoterapia
45: 5-27.
Araujo, L.M.P.C., Thomazine, J.A., Lopez, R.F.V. (2010) Development of
microemulsions to topically deliver 5-aminolevulinic acid in photodynamic
therapy. Eur. J. Pharm. Biopharm. 75(1): 48-55.
References
-271-
Bae, Y., Jang, W.D., Nishiyama, N., Fukushima, S., Kataoka, K. (2005) Multifunctional
polymeric micelles with folate-mediated cancer cell targeting and pH-triggered
drug releasing properties for active intracellular drug delivery. Mol. Biosyst. 1:
242-250.
Baghel, U.S., Singhal, M., Gupta, M.M., Singh, H.P., Sahu, M. (2009) Analytical method
validation for tablet of phenoxymethyl penicillin potassium by RP-HPLC method.
J. Chem. Pharm. Res. 1(1): 271-275.
Bahia, A.P., Azevedo, E.G., Ferreira, L.A., Frezard, F. (2010) New insights into the
mode of action of ultradeformable vesicles using calcein as hydrophilic
fluorescent marker. Eur. J. Pharm. Sci. 39: 90-96.
Bakowsky, U., Kissel, T. (2007)
Poly (vinyl alcohol)-graft-poly(lactide-co-glycolide)
nanoparticles for local delivery of paclitaxel for restenosis treatment. J. Control.
Release 119(1): 41-51.
Bangham, A.D., Horne, R.W. (1964) Negative staining of phospholipids and their
structural modification by surface- active agents as observed in the electron
microscope. J. Mol. Biol. 8: 660-668.
Bao A., Goins B., Klipper, R., Negrete, G., Phillips, W.T. (2004) Direct 99mTc labeling
of pegylated liposomal doxorubicin (Doxil) for pharmacokinetic and non-invasive
imaging studies. J. Pharmacol. Exp. Ther. 308(2): 419-425.
Bechara, F.G., Sand, M., Hoffmann, K., Sand, D., Altmever, P., Stuker, M. (2007) Fat
tissue after lipolysis of lipomas: A histpathological and immunohistochemical
study. J. Cutan. Pathol. 34(7): 552-559.
Berrada, M., Serreqi, A., Dabbarh, F., Owusu, A., Gupta, A., Lehnert, S. (2005) A novel
non-toxic camptothecin formulation for cancer chemotherapy. Biomaterials 26:
2115-2120.
Bharadwaj, R., Yu, H. (2004) The spindle checkpoint, aneuploidy, and cancer. Oncogene
23 (11): 2016-2027.
References
-272-
Bilensoy, E., Gürkaynak, O., Dogan, A., Hincal, A. (2008) Safety and efficacy of
amphiphilic β-cyclodextrin nanoparticles for paclitaxel delivery. Int. J. Pharm.
347: 163-170.
Biswas, S., Dodwadkar, N.S., Deshpande, P.P., Torchilin, V.P. (2012) Liposomes
loaded with paclitaxel and modified with novel triphenylphosphonium-PEG-PE
conjugate possess low toxicity, target mitochondria and demonstrate enhanced
antitumor effects in vitro and in vivo. J. Control. Release 159(3): 393-402.
Bommannan, D., Potts, R.O., Guy, R.H. (1991) Examination of the effect of ethanol on
human stratum corneum in vivo using infrared spectroscopy. J. Control. Release
16(3): 299-304.
Bouwstra, J. A., Gooris, G.S. (2010) The lipid organization in human stratum corneum
model systems. Open. Derm. J. 4: 10-13.
Bouwstra, J.A., Honeywell-Nguyen, P.L. (2002) Skin Structure and mode of action of
vesicles. Adv. Drug. Del. Rev. 54(1): S41-S55.
Bouwstra, J.A., Honeywell-Nguyen, P.L., Gooris, G.S., Ponec,M. (2003) Structure of
skin barrier and its modulation by vesicular formulations. Progress in lipid res.
42:1-36.
British pharmacopeia (2009) Paclitaxel 1: 4505.
Brito, D.A., Yang, Z., Rieder, C.L. (2008) Microtubules do not promote mitotic slippage
when the spindle assembly checkpoint cannot be satisfied. J. Cell Biol. 182 (4):
623-629.
Burger, K.N., Staffhorst, R.W., De Vijlder, H.C., Velinova, M.J., Bomans, P.H.,
Frederik, P. M., De Kruijff, B. (2002) Nanocapsules: lipid-coated aggregates of
cisplatin with high cytotoxicity. Nat. Med. 8: 81-84.
Cai, S., Thati, S., Bagby, T.R., Diabw Mustafa, H., Davies, N.M., Cohen, M.S., Forrest,
M.L. (2010) Localized doxorubicin chemotherapy with a biopolymeric
nanocarrier improves survival and reduces toxicity in xenografts of human breast
cancer. J. Control. Release 146: 212-218.
References
-273-
Cavalli, R., Caputo, O., Gasco, M.R. (2000) Preparation and characterization of solid
lipid nanospheres containing paclitaxel. Eur. J. Pharm. Biopharm. 10: 305-309.
Cevc, G. (1993a) Phospholipids Handbook: Marcel Dekker, NY, Basel, Hong Kong.
215-240.
Cevc, G. (1996) Transfersomes, liposomes and other lipid suspensions on the skin:
permeation enhancement, vesicle penetration and transdermal drug delivery. Crit.
Rev. Ther. Drug Carrier Syst. 13: 257-388.
Cevc, G., Blume, G. (1992) Lipid vesicles penetrate into the skin owing to the
transdermal osmotic gradients and hydration force. Biochim. Biophys. Acta.
1104: 226-232.
Cevc, G., Blume, G., Schatzlein, A. (1997) Transfersomes mediated transepidermal
delivery improves the regiospecificity and biological activity of corticosteroids in
vivo. J. Control. Release 45: 211-226.
Cevc, G., Blume, G., Schatzlein, A., Gebauer, D., Paul, A. (1996) The skin: a pathway
for systematic treatment with patches and lipid based agent carriers. Adv. Drug
Deliv. Rev. 18: 349-378.
Cevc, G., Gebauer, D., Schatzlein, A., Blume, G. (1998) Ultraflexible vesicles
transfersomes have an extremely low pore penetration resistance and transport
therapeutic amounts of insulin across the intact mammalian skin. Biochim.
Biophys. Acta. 1368: 210-225.
Cevc, G., Schatzlein, A., Blume, G. (1995) Transdermal drug carriers: Basic properties,
optimization and transfer efficiency in the case of epicutaneously applied
peptides. J. Control. Release 36: 3-16.
Cevc, G., Schatzlein, A., Richardsen, H. (2002) Ultradeformable lipid vesicles can
penetrate the skin and other semi-permeable barriers unfragmented. Evidence
from double label CLSM experiments and direct size measurements. Biochim.
Biophys. Acta 1564: 21-30.
References
-274-
Chakravarthi, S.S., De, S., Miller, D.W., Robbinson, D.H. (2010) Comparison of anti-
tumor efficacy of paclitaxel delivered in nano- and microparticles. Int. J. Pharm.
383: 37-44.
Chandrasekhar, N.S. and Shobha Rani, R.H. (2009) Microprocessor in controlled
transdermal drug delivery of anti-cancer drugs. J. Mater. Sci. Mater. Med.
20:189-194.
Chang, R.S., Kim, J., Lee, H.Y., Han, S.-E., Na, J., Kim, K., Kwon, I.C., Kim, Y.B., Oh,
Y.-K. (2010) Reduced dose-limiting toxicity of intraperitoneal mitoxantrone
chemotherapy using cardiolipin-based anionic liposomes. Nanomed:
Nanotechnol. 6(6): 769-776.
Chapman, S.J., Walsh, A. (1990) Arch: Desmosomes, corneosomes and desquamation.
An ultra structural study of adult pig epidermis. Dermatol. Res. 282: 304-320.
Chenite, A., Chaput, C., Wang, D., Combes, C., Buschmann, M.D., Hoemann, C.D.,
Leroux, J.C., Atkinson, B.L., Binette, F., Selmani, A. (2000) Novel injectable
neutral solution of chitosan form biodegradable gels in situ. Biomaterials 21:
2155-2161.
Chenite, M., Buschmann, D., Wang, C., Kandani, N. (2001) Rheological characterization
of thermogelling chitosan/glycerophosphate solutions. Carbohydrate polymers
46: 39-47.
Chi, L.M., Wu, W.G. (1991) Mechanism of hemolysis of red blood cell mediated by
ethanol. Biochim. Biophys. Acta. 1062: 46-50.
Chun Lei, Li., Cui, J., Wang, C., Li, Y., Zhang , H.W., Wang, J.X., Li , Y.H., Zhang , L.,
Guo, W.M., Wang, Y.L. (2008) Encapsulation of mitoxantrone into Pegylated
SUVs enhances its antineoplastic efficacy. Eur. J. Pharm. Biopharm. 70: 657-
665.
Chun, C., Lee, S.M., Kim, S.Y., Yang, H.K., Song, S.C. (2009) Thermosensitive poly
(organophosphazene)-paclitaxel conjugate gels for antitumor applications.
Biomaterials 30: 2349-2360.
References
-275-
Cochran, M.C., Eisenbrey, J., Ouma, R.O., Soulen, M., Wheatley, M.A. (2011)
Doxorubicin and paclitaxel loaded microbubbles for ultrasound triggered drug
delivery. Int. J. Pharm. 414(1-2): 161-170.
Cohen, S., Lobel, E., Trevgoda, A., Peled, Y. (1997) A novel in situ-forming ophthalmic
drug delivery system for alginates undergoing gelation in the eye. J. Control.
Release 44: 201-208.
Corsini, E., Galli, C.L. (1986) Cytokines and irritant contact dermatitis. Toxicol. Lett.
102/103: 277-282.
Cosco, D., Paolino, D., Muzzalupo, R., Celia, C., Citraro, R., Caponio, D., Picci, N.,
Fresta, M. (2009) Novel PEG-coated niosomes based on bola-surfactant as drug
carriers for 5-fluorouracil. Biomed. Microdevices 11(5): 1115-1125.
Crompton, K.E., Prankerd, R.J., Paganin, D.M., Scott, T.F., Horne, M.K., Finkelstein,
D.I., Gross, K.A., Forsythe, J.S. (2005) Morphology and gelation of
thermosensitive chitosan hydrogels. Biophys. Chem. 117: 47-53.
Crosasso, P., Ceruti, M., brusa, P., Arpicco, S., Dosio, F., Cattel, L. (2000) Preparation,
characterization and properties of sterically stabilized paclitaxel-containing
liposomes. J. Control. Release 63(1-2): 19-30.
Curic, N.D., Grafe, S., Albrecht, V., Fahr, A. (2008) Topical application of temoporfin-
loaded invasomes for photodynamic therapy of subcutaneously implanted tumors
in mice: A pilot study. J. Photochem. Photobiol. B 91: 41-50.
De Mario, M.D., Ratain, M.J. (1998) Oral chemotherapy: rationale and future directions.
J. Clin. Oncol. 16: 2557-2567.
Desai, N., Trieu, V., Yao, Z., Louie, L., Ci, S., Yang, A., Tao, C., De, T., Beals, B.,
Dykes, D., Noker, P., Yao, R., Labao, E., Hawkins, M., Soon-Shiong, P. (2006)
Increased antitumor activity, intratumor paclitaxel concentrations and endothelial
cell transport of Cremophor-free, albumin-bound paclitaxel, ABI-007, compared
with Cremophor-based paclitaxel. Clin. Cancer Res. 12: 1317-1324.
References
-276-
Desai, P.B., Duan, J. Z., Kouzi, S. (1998) Human liver microsomal metabolism of
pacliaxel and drug interactions. Eur J Drug Metab Pharmacokineict 23(3): 417-
424.
Dhanikula, A.B., Panchagnula, R. (1999) Localized paclitaxel delivery. Int. J. Pharm.
183:85-100
Dhanikula, A.B., Panchagnula, R. (2004) Development and characterization of
biodegradable chitosan films for local delivery of paclitaxel. AAPS J. 6(3): 1-12.
Dong, Y., Feng, S.S. (2004) Methoxy poly(ethylene glycol)-poly(lactide) (MPEG-PLA)
nanoparticles for controlled delivery of anticancer drugs. Biomaterials 25: 2843-
2849.
Dong, Y., Zhang, Z., Feng, S.S. (2008) d-alpha-Tocopheryl polyethylene glycol 1000
succinate (TPGS) modified poly(l-lactide) (PLLA) films for localized delivery of
paclitaxel. Int. J. Pharm. 350: 166-171.
Draize, J., Woodard, G., Calvery, H. (1944) Methods for the study of irritation and
toxicity of substance applied to the skin and mucous membranes. J. Pharmacol.
Exper. Therap. 82: 377-390.
Dreis, S., Rothweiler, F., Michaelis, M., Cinatl, J. J., Kreuter, J., Langer, K. (2007)
Preparation, characterization and maintenance of drug efficacy of doxorubicin-
loaded human serum albumin (HSA) nanoparticles. Int. J. Pharm. 341: 207-214.
Drummond, D.C., Meyer, O., Hong, K., Kirpotin, D.B., Papahadjopoulos (1999)
Optimizing liposomes for delivery of chemotherapeutic agents to solid tumors.
Pharm. Rev. 51(4): 691-744.
Du Plessis, J., Ramachandran, C., Weiner, N., Müller, D.G. (1994) The influence of
particle size of liposomes on the disposition of drug into the skin. Int. J. Pharm.
103: 277-282.
Dubey, V., Mishra, D., Asthana, A., Jain, N.K. (2006) Transdermal delivery of a pineal
hormone: Melatonin via elastic liposomes. Biomaterials 27: 3491-3496.
References
-277-
Egbaria, K., Ramachandran, C., Weiner, N. (1990) Topical delivery of cyclosporin A:
evaluation of various formulations using in vitro diffusion studies in hairless
mouse skin. Skin Pharmacol. 321-328.
El Maghraby, G.M.M., Williams, A.C., Barry, B.W. (1999) Skin delivery of oestradiol
from deformable and traditional liposomes: Mechanistic studies. J. Pharm.
Pharmacol. 51: 1123-1134.
El Maghraby, G.M.M., Williams, A.C., Barry, B.W. (2000) Skin delivery of oestradiol
from lipid vesicles: Importance of liposome structure. Int. J. Pharm. 204: 159-
169.
El Maghraby, G.M.M., Williams, A.C., Barry, B.W. (2001) Skin delivery of 5-
fluorouracil from ultra deformable and standard liposomes in vitro. J. Pharm.
Pharmacol. 53: 1069-1077.
El Meshad, A.N., Tadros, M.I. (2011) Transdermal delivery of an anti-cancer drug via
w/o emulsions based on alkyl polyglycosides and lecithin: Design,
characterization, and in vivo evaluation of the possible irritation potential in rats.
AAPS. Pharm. Sci. Tech. 12(1):1-9.
Elias, P.M., Cooper, E.R., Korc, A., Brown, B.E. (1981) Percutaneous transport in
relation to stratum corneum structure and lipid composition. J. Invest. Dermatol.
76, 297-301.
Elisseeff, J., Anseth, K., Sims, D., Mcintosh, W., Randolph, M., Langer, R. (1999)
Transdermal photopolymerization for minimally invasive implantation. Proc. Nat.
Acad. Sci. U.S.A. 96: 3104-3107.
Elstad, N.L., Fowers, K.D. (2009) OncoGel (ReGel/paclitaxel)-clinical applications for a
novel paclitaxel delivery system. Adv. Drug Del. Rev. 61: 785-794.
Emmanuel, A.H., Patrick, L.S., Christine, A., Micheline, P.M. (2007) Impact of
intraperitoneal, sustained delivery of paclitaxel on the expression of P-
glycoprotein in ovarian tumors. J. Control. Release 117: 20-27.
References
-278-
Emmanuel, A.H., Vessela, V., Christine, A., Micheline, P.M. (2005) In vitro and in vivo
characterization of a novel biocompatiable polymer-lipid implants system for the
sustained delivery of paclitaxel. J. Control. Release 104: 181-191.
Ermolaeva, L.A., Dubskaya, T.Y., Fomina, T.I., Vetoshkina, T.V., Goldberg, V.E. (2008)
Toxic effect of an antitumor drug paclitaxel on morphofunctional characteristics
of the liver in rats. Bull. Exp. Bio. Med. 145: 225-228.
Essa, E.A, Bonner, M.C., Barry, B.W. (2002) Iontophoretic estradiol skin delivery and
tritium exchange in ultradeformable liposomes. Int. J. Pharm. 240: 55-66.
Fang, J.Y., Lin, H.H., Hsu, L.R., Tsai, Y.H. (1997) Characterization and stability of
various liposome-encapsulated enoxacin formulations. Chem. Pharm. Bull. 45:
1504-1509.
Feng, S.S., Mu, L., Chen, B.H., Daniel, P. (2002) Polymeric nanospheres fabricated with
natural emulsifiers for clinical administration of an anticancer drug paclitaxel.
Material Sci. Eng. C20: 85-92.
Ferlay, J., Shin, H.R., Bray, F., Forman, D., Mathers, C., Parkin, D.M. (2010) Estimates
of worldwide burden of cancer in 2008: GLOBOCAN 2008. Int. J. Cancer 127:
2893-2917.
Fernandez, C.B., Font, A.F., Merino, V., Diaz, D.C., Barroeta, M.E., Castellano, A.L.,
Diaz, M.C. (2011) Elastic vesicles of sumatriptan succinate for transdermal
administration: Characterization and in vitro permeation studies. J. Liposome
Res. 21(1): 55-59.
Floyd, A.G. (1999) Top ten considerations in the development of parenteral emulsions.
Pharm. Sci. Techl. Today 2: 134-143.
Folch, J., Lees, M., Sloane-Stanley, G.H. (1957) A simple method for the isolation and
purification of total lipids from animal tissues. J. Biol. Chem. 226:497-502.
Fonseca, C., Simoes, S., Gaspar, R. (2002) Paclitaxel-loaded PLGA nanoparticles:
Preparation, physicochemical characterization and in vitro anti-tumoral activity.
J. Control. Release 83: 273-286.
References
-279-
Frairia, M.R. Gascoc, M. Eandi, Zara, G.P. (2004) Cytotoxicity of anticancer drugs
incorporated in solid lipid nanoparticles on HT-29 colorectal cancer cell line. Eur.
J. Pharm. Biopharm. 58: 673-680.
Fung, L.K., Saltzman, W.M. (1997) Polymeric implants for cancer chemotherapy. Adv.
Drug Deli. Rev. 26(2-3): 209-230.
Garcion, E., Lamprecht, A., Heurtault, B., Paillard, A., Aubert-Pouessel, A.,
Denizot,Philippe Menei, B., Benoıt, J.P. (2006) A new generation of anticancer,
drug-loaded, colloidal vectors reverses multidrug resistance in glioma and reduces
tumor progression in rats. Mol. Cancer Ther. 5(7): 1710-1722.
Garg, T., Jain, S., Singh, H., Sharma, A., Tiwary, A.K. (2008) Elastic liposomal
formulation for sustained delivery of antimigraine drug: In vitro characterization
and biological evaluation. Drug Dev. Ind. Phar. 34(10): 1100-1110.
Garidel, P. (2002) Mid-FTIR-Microspectroscopy of stratum corneum single cells and
stratum corneum tissue. Phys. Chem. Chem. Phys. 4: 5671-5677.
Gariepy, E.R., Leclair, G., Hildgen, P., Gupta, A., Leroux, B. (2002) Thermo sensitive
chitosan-based hydrogel containing liposomes for the delivery of hydrophilic
molecules. J. Control. Release 82: 373-383.
Gelderblom, H. (2001) Cremophor EL the drawbacks and advantages of vehicle selection
for drug formulation. Eur. J. Cancer 37(13): 1590-1598.
Gelfuso, G.M., Figueiredo, F.V., Gratieri, T., Lopez, R.F.V. (2008) The effect of pH and
ionic strength on topical delivery of a negatively charged porphyrin (TPPS4). J.
Pharm. Sci. 97: 4249-4257.
Gelfuso, G.M., Gratieri, T., Souza, J.G., Thomazine, J.A., Lopez, R. F.V. (2011) The
influence of positive or negative charges in the passive and iontophoretic skin
penetration of porphyrins used in photodynamic therapy. Eur. J. Pharm.
Biopharm. 77(2): 249-256.
Gerald, J.F., Robert, M.S. (2003) Pharmacokinetics of paclitaxel-containing liposomes in
rat. APPS Pharm. Sci. Tech. 5(4):90-100.
References
-280-
Gilbert, J.C., Richardson, J.L., Davies, M.C., Palin, K.J., Hadgraft, J. (1987) The effect of
solutes and polymers on the gelation properties of pluronic F-127 solutions for
controlled drug delivery. J. Control. Release 5: 113-118.
Gill, KK., Nazzal, S., Kaddoumi, A. (2011) Paclitaxel loaded PEG (5000)-DSPE micelles
as pulmonary delivery platform: formulation characterization, tissue distribution,
plasma pharmacokinetics, and toxicological evaluation. Eur. J. Pharm.
Biopharm. 79(2): 276-284.
Glavas-Dodov, M., Kumba-Radzi, E.F., Goracinova, K., Calis, S., Simonoska, M.,
Hincal, A. (2003) 5-Fluorouracil in topical liposome gels for anticancer treatment-
Formulation and evaluation. Acta. Pharm. 53: 241-250.
Golden, G.M., Guzek, D.B., Harris, R.R., McKie, J.E., Potts, R.O. (1986) Fourier
Transform Raman Spectroscopy. J. Invest. Dermatol. 86: 255-259.
Golden, G.M., McKie, J.E., Potts, R.O. (1987) Role of stratum corneum lipid fluidity in
transdermal drug flux. J. Pharm. Sci. 76: 25-28.
Gompper, G., Kroll, D.M. (1995) Driven transport of fluid vesicles through narrow pores.
Phys. Rev. E-52: 4198-4208.
Gottesman, M.M. (2002) Mechanisms of cancer drug resistance. Annu. Rev. Med. 53:
615-627.
Gradishar, W.J., Tjulandin, S., Davidson, N., Shaw, H., Desai, N., Bhar, P., Hawkins, M
(2005) Phase III trial of nanoparticle albumin bound paclitaxel compared with
polyethylated castor oil based paclitaxel in women with breast cancer. J. Clin.
Oncology 23 (31): 7794-7803.
Gregoriadis, G. (1976a) The carrier potential of liposomes in biology and medicine. (Part
one of two parts) N. Engl. J. Med. 295: 704-710.
Gregoriadis, G. (1976b) The carrier potential of liposomes in biology and medicine. (Part
two of two parts) N. Engl. J. Med. 295: 765-770.
Guo, J., Ping, Q., Sun, G., Jiao, C. (2000) Lecithin vesicular carriers for transdermal
delivery of cyclosporine A. Int. J. Pharm. 194: 201-207.
References
-281-
Gupta, P.N., Mishra, V., Rawat, A., Dubey. P.K., Mahor, S., Jain, S., Chatterji, D.P.
Vyas, S.P. (2005) Non-invasive vaccine delivery in transfersomes, niosomes and
liposomes: a comparative study. Int. J. Pharm. 293: 73-82.
Hamidi, M., Azadi, A., Raei, P. (2008) Hydrogel nanoparticles in drug delivery. Adv.
Drug Deliv. Rev. 60: 1638-1649.
Hamilton, M.A., Russo, R.C., Thurston, R.C. (1977) Trimmed Spearman-karber method
for estimating median lethal concentration in toxicity bioassays. Env. Sci.
Technol. 7: 714-719.
Han, H.D., Chol, M.S., Hwang, T., Song, C.K., Seong, H., Kim, T.W., Choi, H.S., Shin,
B.C. (2006) Hyperthermia-induced anti-tumor activity of thermosensitive
polymer modified temperature -sensitive liposomes. J. Pharm. Sci. 95(9): 1909-
1917.
Han, H.D., Shin, B.C., Choi, H.S. (2006) Doxorubicin-encapsulated thermosensitive
liposomes modified with poly(N-isopropylacrylamide-co-acrylamide): Drug
release behavior and stability in the presence of serum. Eur. J. Pharm.
Biopharm. 62(1): 110-116.
Hana, X., Liua, J., Liua, M., Xiea, C., Zhana, C., Gua, B., Liua, Y., Fenga, L., Lua, W.
(2009) 9 NC-loaded folate-conjugated polymer micelles as tumor targeted drug
delivery system: Preparation and evaluation in vitro. Int. J. Pharm. 372: 125-131.
Hao, Y.L., Deng, Y.J., Chen, Y., Wang, X.M., Jun, H., Zhong, S. X.B. (2005) In vitro
and in vivo studies of different liposomes containing topotecan. Arch. Pharm.
Res. 28: 626-635.
Haq, M.I., Smith, E., John, D.N., Kalavala, M., Edwards, C., Anstey, A., Morrissey, A.,
Birchall, J.C. (2009) Clinical administration of microneedles: skin puncture, pain
and sensation. Biomed. Microdevices 11: 35-47.
Heldman, A.W., Cheng, L., Jenkins, G.M., Heller, P.F., Kim, D.W., Ware Jr, M., Nater,
C., Hruban, R.H . (2001) Paclitaxel stent coating inhibits neointimal hyperplasia
References
-282-
at 4 weeks in a porcine model of coronary restenosis. Circulation 103 (18): 2289-
2295.
Heney, M., Alipour, M., Vergidis, D., Omri, A., Mugabe, C., Thng, J., Suntres, Z. (2010)
Effectiveness of liposomal paclitaxel against MCF-7 breast cancer cells. Can. J.
Physiol. Pharmacol. 88: 1172-1180.
Herai, H., Gratieri, T., Thomazine, J.A., Bentley, M.V.L.B., Lopez, R.F.V. (2007)
Doxorubicin skin penetration from monoolein-containing ropylene glycol
formulations. Int. J. Pharm. 329 (1-2): 88-93.
Herdeg, C., Oberhoff, M., Baumbach, A., Blattner, A., Kuttner, A., Schroder, S., Haase,
K.K., Karsch, K.R. (1999) Visualization and comparison of drug effects after
local paclitaxel delivery with different catheter types. Basic Res. Cardiol. 94:
454-463.
Higashi, S., Tabata, N., Kondo, K. H., Maeda, Y., Shimizu, M., Nakashima, T.,
Setoguchi, T. (1999) Size of lipid microdroplets effects results of hepatic arterial
chemotherapy with an anticancer agent in water-in-oil-in-water emulsion to
hepato-cellular carcinoma. J. Pharmacol. Exp. Ther. 289: 816-819.
Ho, E.A., Soo, P.L., Allen, C., Miller, M.P. (2007) Impact of intraperitoneal, sustained
delivery of paclitaxel on the expression of P-glycoprotein in ovarian tumors. J.
Control. Release 117: 20-27.
Ho, E.A., Vassileva, V., Allen, C., Miller, M.P. (2005) In vitro and in vivo
characterization of a novel biocompatible polymer-lipid implant system for the
sustained delivery of paclitaxel. J. Control. Release 104(1): 181-191.
Hofer, C., Göbel, R., Deering, P., Lehmer, A., Breul, J. (1999) Formulation of
interleukin-2 and interferon-alpha containing ultradeformable carriers for
potential transdermal application. Anticancer Res. 19: 1505-1507.
Hofer, C., Hartung, R., Gobel, R., Deering, P., Lehmer, A., Breul, J. (2000) New
ultradeformable drug carriers for potential transdermal application of interleukin-
References
-283-
2 and interferon-alpha: Theoretical and practical aspects. World J. Surg. 24:
1187-1191.
Hofer, C., Randenborgh, H.V., Lehmer, A., Hartung, R., Breul. J. (2004) Transcutaneous
IL-2 uptake mediated by transfersomes depends on concentration and fractionated
application. Cytokine 25: 141-146.
Honeywell-Nguyen, P.L., Bouwstra, J.A. (2003) The in vitro transport of pergolide from
surfactant-based elastic vesicles through human skin: a suggested mechanism of
action. J. Control. Release 86: 145-156.
Honeywell-Nguyen, P.L., de Graaff, A.M., Wouter Groenink, H.W., Bouwstra, J.A.
(2002a) The in vivo and in vitro interactions of elastic and rigid vesicles with
human skin. Biochim. Biophys. Acta. 1573: 130-140.
Honeywell-Nguyen, P.L., Frederik, P.M., Bomans P.H.H., Junginger, H.E. Bouwstra,
J.A. (2002) Transdermal delivery of pergolide from surfactant based elastic and
rigid vesicles: Characterization and in vitro transport studies. Pharm. Res. 19 (7):
991-997.
Hunter, W.L., Burt H.M., Machan, L. (1997) Local delivery of chemotherapy: a
supplement to existing cancer treatments. A case for surgical pastes and coated
stents. Adv. Drug. Deliv. Rev. 26: 199-207.
Hureaux, J., Lagarce, F., Gagnadoux, F., Marie-Christine, R., Moal, V., Urban, T.,
Benoit, J.P. (2010) Toxicological study and efficacy of blank and paclitaxel-
loaded lipid nanocapsules after i.v. administration in mice. Pharm. Res. 27(3):
421-430.
Jain, A., Agarwal, A., Majumder, S., Lariya, N., Khaya, A., Himanshu, A., Majumdar, S.,
Agrawal, G.P. (2010) Mannosylated solid lipid nanoparticles as vectors for site-
specific delivery of an anti-cancer drug. J. Control. Release 148(3): 359-367.
Jain, N.K., Mishra, D., Garg, M., Dubey, V., Jain, S. (2006) Elastic liposomes mediated
transdermal delivery of an anti-hypertensive agent: propranolol hydrochloride. J.
Pharm. Sci. 96: 145-155.
References
-284-
Jain, R. K. (1994) Barriers to drug delivery in solid tumors. Sci. Am. 271: 58-65.
Jain, S., Jain, N., Bhadra, D., Jain, N.K. (2005) Transdermal delivery of an analgesic
agent using elastic liposomes: preparation, characterization and performance
evaluation. Curr. Drug Deliv. 2: 1-11.
Jain, S., Jain, N., Bhadra, D., Tiwary, A.K., Jain, N.K. (2005b) Transdermal delivery of
an analgesic agent using elastic liposomes: preparation, characterization and
performance evaluation. Curr. Drug Deliv. 2(3): 223-233.
Jain, S., Jain, N.K., Tiwary, A.K. (2008) PEGylated elastic liposomal formulation for
lymphatic targeting of zidovudine. Curr. Drug. Deliv. 5: 275-281.
Jain, S., Jain, P., Umamaheshwari, R.B., Jain, N.K. (2003a) Transfersomes-A novel
vesicular carrier for enhanced transdermal delivery: development,
characterization, and performance evaluation. Drug Dev. Ind. Pharm. 29: 1013-
1026.
Jain, S., Sapre, R., Tiwary, A.K. Jain, N.K. (2005a) Proultraflexible lipid vesicles for
effective transdermal delivery of levonorgestrel: Development, characterization,
and performance evaluation. AAPS Pharm. Sci. Tech. 6: E513-522.
Jain, S., Sapre, R., Umamaheshwari, R.B. Jain, N.K. (2003b) Protransfersomes for
effective transdermal delivery of levonorgestrel preparation and in vitro
characterization. Int. J. Pharm. Sci. 65: 152-161.
Jain, S., Tiwary, A.K., Jain, N.K. (2006) Sustained and targeted delivery of anti-HIV
agent using elastic liposomal formulation: Mechanism of action. Curr. Drug
Deliv. 3(2): 157-166.
Jain, S., Tiwary, A.K., Jain, N.K. (2008) PEGylated elastic liposomal formulation for
lymphatic targeting of zidovudine. Curr. Drug Deliv. 5: 275-281.
Jauhari, S., Dash, A.K. (2006) Mucoadhesive in situ gel delivery system for paclitaxel.
AAPS Pharm. Sci. Tech. 7(2): E154-E159.
Jemal, A., Siegel, R., Xu, J., Ward, E. (2010) Cancer statistics, CA. Cancer J. Clin.
60(144): 277-300.
References
-285-
Jemel, F. Bray., J, Ferlay., E. Ward, D, Forman. (2011) Global cancer statistics. Cancer
J. Clin. 61: 69-90.
Jeong, B., Bae, Y.H., Lee, D.S., Kim, S.W. (1997) Biodegradable block copolymers as
injectable drug-delivery systems. Nature 388: 860-862.
Johnston, T.P., Punjabi, M.A., C.J. Froelich (1992) Sustained delivery of interleukin-2
from a poloxamer 407 gel matrix following intraperitoneal injection in mice.
Pharm. Res. 9: 425-434.
Jonkman-deVries, J.D., Flora, K.P., Bult, A., Beijnen, J.H. (1996) Pharmaceutical
development of investigational anticancer agents for parenteral use - a review.
Drug Dev. Ind. Pharm. 22: 475-494.
Jubo, L., Lee, H., Huesca, M., Young, A., Allen, C. (2006) Liposome formulation of a
novel hydrophobic aryl-imidazole compound for anti-cancer therapy. Cancer
Chemother. Pharmacol. 58: 306-318.
Jumaa, M., Muller, B.W. (2000) Lipid emulsions as a novel system to reduce the
hemolytic activity of lytic agents: mechanism of the protective effect. Eur. J.
Pharm. Sci. 9: 285-290.
Jung, T., Kamm W., Breitenbach A., Kaiserling E., Xiao J.X., Kissel T. (2000)
Biodegradable nanoparticles for oral delivery of peptides: is there a role for
polymers to affect mucosal uptake? Eur. J. Pharm. Biopharm. 50: 147-160.
Kaisera, N., Kimpfler, A., Massing, U., Burger, A.M., Fiebig, H.H., Brandl, M.,
Schubert, R. (2003) 5-Fluorouracil in vesicular phospholipid gels for anticancer
treatment: entrapment and release properties. Int. J. Pharm. 256: 123-131.
Kaminskas, L.M., Kelly, B.D., McLeod, V.M., Sberna, G., Owen, D.J., Boyd,
B.J., Porter, C.J. (2011) Characterization and tumour targeting of PEGylated
polylysine dendrimers bearing doxorubicin via a pH labile linker. J. Control.
Release152 (2): 241-248.
References
-286-
Kan, P., Chen, Z.B., Lee, C.J., Chu, I.M. (1999) Development of nonionic surfactant/
phospholipids o/w emulsion as a paclitaxel delivery system. J. Control. Release
58: 271-278.
Kang, B.K., Kang, S., Kim, S.H., Jeong, S.Y., Kim, M.S., Cho, S.H., Lee, H.B., Khang,
G. (2004) Controlled release of paclitaxel from micro emulsion containing PLGA
and evaluation of anti-tumor activity in vitro and in vivo. Int. J. Pharm. 286: 147-
156.
Kataoka, K., Harada, A., Nagasaki, Y. (2001) Block copolymer micelles for drug
delivery: design, characterization and biological significance. Adv. Drug Deliv.
Rev. 47: 113-131.
Kataoka, K., Kwon, G.S., Yokoyama, M., Okano, T., Sakurai, Y. (1993) Block
copolymer micelles as vehicles for drug delivery. J. Control. Release 24: 119-
132.
Kaur N, Puri R, Jain S. (2010) Drug cyclodextrin -Vesicles dual carrier approach for
skin targeting of anti-acne agent. APPS PharmSci. Tech. 11:528–537.
Kaur, N., Puri, R., Jain, S. (2010) Drug cyclodextrin-vesicles dual carrier approach for
skin targeting of anti-acne agent. APPS Pharm. Sci. Tech. 11: 528-537.
Khandavilli, S., and Panchagnula, R. (2007) Nanoemulsions as versatile formulations for
paclitaxel delivery: Peroral and dermal delivery studies in rats. J. of Invest. Derm.
127: 154-162.
Khurana, S., Utreja, P., Tiwary, A.K., Jain, S. (2009) Nanostructured lipid carriers and
their application in drug delivery. Int. J. Biomedical Eng. Technol. 2: 152-171.
Kievit, F.M., Wang, F.Y., Fang, C., Mok, H., Wang, K., Silber, J.R., Ellenbogen, R.G.,
Zhang, M. (2011) Doxorubicin loaded iron oxide nanoparticles overcome
multidrug resistance in cancer in vitro. J. Control. Release 152: 76-83.
Kilicay, E., Demirbilek, M., Turk, M., Guven, E., Hazer, H., Denkbas, E.B. (2011)
Preparation and characterization of poly(3-hydroxybutyrate-co-3-
References
-287-
hydroxyhexanoate) (PHBHHX) based nanoparticles for targeted cancer therapy.
Eur. J. Pharma. Sci. 44: 310-320.
Kim, A., Lee, E.H., Choi, S.H., Kim, C.K. (2004) In vitro and in vivo transfection
efficiency of a novel ultradeformable cationic liposome. Biomaterials 25: 305-
313.
Kim, J.H., Bae, S.M., Na, M.H., Shin, H., Yang, Y.J., Min, K.H., Choi, K.Y., Kim, K.,
Park, R.W., Kwon, I.C., Lee, B.H., Hoffman, A.S., Kim, I.S. (2012) Facilitated
intracellular delivery of peptide-guided nanoparticles in tumor tissues. J. Control.
Release 157 (3): 493-499.
Kim, M.K., Chung, S.I., Lee, M.H., Shim, C.K. (1998) Delivery of hydrocortisone from
liposomal suspensions to the hairless mouse skin following topical application
under non-occlusive and occlusive conditions. J. Microencapsulation 15: 21-29.
Kim, S.C., Kim, D.W., Shim, Y.H, Bang, J.S., Oh H.S., Kim S.W., Seo, M.H. (2001) In
vivo evaluation of polymeric micellar paclitaxel formulation: toxicity and
efficacy. J. Control. Release 72: 191-202.
Kim, Y.C., Park, J.H., Ludovice, P.J., Prausnitz, M.R. (2008) Synergistic enhancement of
skin permeability by N-lauroylsarcosine and ethanol. Int. J. Pharm. 352(1-2):
129-138.
Kirjavainen, M., Monkkonen, J., Saukkosaari, M., Valjakka-Koskela, R., Kiesvaara, J.,
Urtti, A. (1999) Phospholipids effect stratum corneum lipid bilayer fluidity and
drug partitioning into the bilayers. J. Control. Release 58(2): 207-214.
Kirjavainen, M., Urtti, A., Jaaskelainen, I., Suhonen, T.M., Paronen, P., Valjakka-
Koskela, R., Monkkonen, J. (1996) Interaction of liposomes with human skin in
vitro: the influence of lipid composition and structure. Biochim. Biphys. Acta.
1304: 179-189.
Klein-Szanto, A.J. (1992) Carcinogenic effects of chemotherapeutic compounds. Prog.
Clin. 374: 167-174.
References
-288-
Koudelka, S., Knotigova, P.T., Masek, J., Korvasova, Z., Skrabalova, M., Plockova, J.,
Barthedyova, E., Turanek, J. (2009) Liposomes with high encapsulation capacity
for paclitaxel: preparation, characterization and in vivo anti cancer effect.
J. Pharm. Sci. 99: 2309-2319.
Kramer, I., Heuser, A. (1995) Paclitaxel pharmaceutical and pharmacological issues.
Eur. Hosp. Pharm. 1: 37-41.
Kreuter, J. (2007) Nanoparticles-a historical perspective. Int. J. Pharm. 331: 1-10.
Kupper, T.S. (1990) Role of epidermal cytokines, in: J.J. Oppenheim, E.M. Shevach
(Eds.),: The Role of Cells and Cytokines in Immunity and Inflammation, Oxford
University Press, New York, , pp. 285-305.
Kuttan, G., Vasudevan, D.M., Kuttan, R. (1990) Effect of a preparation from viscum
album on tumour development in vitro and in mice. J. Ethnopharmacol. 29: 35-
41.
Kwon, G. S., Suwa, S., Yokoyama, M., Okano, T., Sakurai, Y., Kataoka, K. (1994)
Enhanced tumor accumulation and prolonged circulation times of micelle-forming
poly(ethylene oxide-aspartate) block copolymer-Adriamycin conjugate.
J. Control. Release 29: 17-23.
Lacoeuille, F., Hindre, F., Moal, F., Roux, J., Passirani, C., Couturier, O., Cales, P., Le
Jeune, J.J., Lamprecht, A., Benoit. J.P. (2007) In vivo evaluation of lipid
nanocapsules as a promising colloidal carrier for paclitaxel. Int. J. Pharm. 344(1-
2): 143-149.
Lasch, J., Laub, P., Woblrab, W. (1991) How deep do intact liposomes penetrate into
human skin? J. Control. Release 18: 55-58.
Lashmar, U.T., Hadgraft, J., Thomas, J. (1989) Topical application of penetration
enhancers to the skin of nude mice: a histopathological study. J. Pharm.
Pharmacol. 41 (2): 118-121.
Lavasanifar, A., Sanuel, J., Kwon, G. (2002) Poly(ethylene oxide)-block-poly (L-amino
acid) micelles for drug delivery. Adv. Drug Deliv. Rev. 54: 169-190.
References
-289-
Lee, S., Yun, M.H., Jeong, S.W., Hoon, C., Kim, J.Y., Seo, M.H., Pai, C.M., Kim, S.O.
(2011) Development of docetaxel-loaded intravenous formulation, Nanoxel-PM™
using polymer-based delivery system. J. Control. Release 155(2): 262-271.
Lee, S.C., Kim, C., Kwon, Chung, H., Jeong, S.Y. (2003) Polymeric micelles of poly(2-
ethyl-2-oxazoline)-block-poly(epsilon-caprolactone) copolymer as a carrier for
paclitaxel. J. Control. Release 89: 437-446.
Li, X., Kong, X., Zhang, J., Wang, Y., Shi, S., Guo, G., Luo, F., Zhao, X., Wei, Y., Qian,
Z. (2011) A novel composite hydrogel based on chitosan and inorganic phosphate
for local delivery of camptothecin nanocolloids. J. Pharm. Sci. 100: 232-241.
Li, X.Y., Kong, X.Y., Wang, X.H., Shi, S., Guo, G., Luo, F., Zhao, X., Wei, Y., Qian, Z.
(2010) Gel-sol-gel thermo-gelation behavior study of chitosan-inorganic
phosphate solutions. Eur. J. Pharm. Biopharm. 75: 388-392.
Li., C.L., Cui, J., Wang, C., Li, Y., Zhang , H.W., Wang, J.X., Li , Y.H., Zhang, L.,
Guo, W.M., Wang, Y.L. (2008) Encapsulation of mitoxantrone into Pegylated
SUVs enhances its antineoplastic efficacy. Eur. J. Pharm. Biopharm. 70: 657-
665.
Liang, Y., Qiao, Y., Guo, S., Wang, L., Zhai, Y., Xie, C., Hu, R., Deng, L., Dong, A.
(2012) Investigation on injectable, thermally and physically gelable poly(ethylene
glycol)/poly(octadecanedioic anhydride) amphiphilic triblock co-polymer
nanoparticles. J. Biomater. Sci. Polym. Ed. 23(1-4): 465-482.
Lichtenberger, L.M., Graziani, L.A., Dial, E.J., Butler, B.D., Hills, B.A. (1983) Role of
surface-active phospholipids in gastric cytoprotection. Science 219: 1327-1329.
Lin, H.H., Cheng, Y.L. (2001) In situ thermoreversible gelation of block and star
copolymers of poly(ethylene glycol) and poly(N-isopropylacrylamide) of varying
architectures. Macromolecules 34: 3710-3715.
Lin, X., Deng, L., Xu, Y., Dong, A. (2012) Thermosensitive in situ hydrogel of paclitaxel
conjugated poly (ε-caprolactone)-poly(ethylene-glycol)- poly (ε-caprolactone).
Soft Matter 12(8): 3470-3477.
References
-290-
Liu, X., Sun, J., Chen, X., Wang, S., Scot, H., Zhan, X., Zhan, Q. (2012)
Pharmacokinetics, tissue distribution and anti-tumour efficacy of paclitaxel
delivered by polyvinylpyrrolidone solid dispersion. J. Pharm. Pharmacol. 775-
782.
Liu, Z., Chen, K., Davis, C., Sherlock, S., Cao, Q., Chen, X., Dai, H. (2008) Drug
delivery with carbon nanotubes for in vivo cancer treatment. Cancer Res. 68:
6652-6660.
Lo, J.T., Chen, B.H., Lee, T.M., Han, J, Li, J.L. (2009) Self emulsifying o/w formulations
of paclitaxel prepared from mixed nonionic surfactants. J. Pharm. Sci. 99 (5):
2320-2332.
Lopez, O., de la Maza, A., Coderch, L., Lopez-Lglesias, C., Wehrli, E., Parra, J.L. (1998)
direct formation of mixed micelles in the solubilization of phospholipid liposomes
by Triton X-100. FEBS Lett. 426(3): 314-318.
Lowenthal, R.M., Eaton, K. (1996) Toxicity of chemotherapy. Oncol. Clin. North Am.
10: 967-990.
Lu, B., Xiong, S.B., Yang, H., Yin, X.D., Zhao, R.B. (2006) Mitoxantrone-loaded BSA
nanospheres and chitosan nanospheres for local injection against breast cancer
and its lymph node metastases II. Tissue distribution and pharmacodynamics. Int.
J. Pharm. 307: 175-181.
Lu, J., Liong, M., Zink, J.I., Tamanol, F. (2007) Mesoporous silica nanoparticles as a
delivery system for hydrophobic anti-cancer drugs. Small 3: 1341-1346.
Luo, X., Xie, C., Wang, H., Liu, C., Yan, S., Li, X. (2012) Antitumor activities of
emulsion electrospun fibers with core loading of hydroxyl camptothecin via
intratumoral implantation. Int. J. Pharm. 425(1-2): 19-28.
Mackay, H.J., Provencheur, D., Heywood, M., Tu, D., Eisenhauer, E.A., Oza, A.M.,
Meyer, R. (2011) Phase II/III study of intraperitoneal chemotherapy after
neoadjuvant chemotherapy for ovarian cancer. Curr. Oncol. 18: 84-90.
References
-291-
Maestrelli, F., González-Rodríguez, M.L., Rabasco, A.M., Ghelardini, C., Mura, P.
(2010) New “drug-in cyclodextrin-in deformable liposomes” formulations to
improve the therapeutic efficacy of local anaesthetics. Int. J. Pharm. 395: 222-
231.
Mahdi, E.S., Sakeena, M.H.F., Abdulkarim, M.F., Abdullah, G.Z., Sattar, M.A., Noor,
A.M. (2011) Effect of surfactant and surfactant blends on pseudo ternary phase
diagram behavior of newly synthesized palm kernel oil esters. Drug Des. Devel.
Ther. 5: 311-323.
Mayer, L.D., Tai, L.C., Ko, D.S., Masin, D., Ginsberg, R.S., Cullis, P.R., Bally, M.B.
(1989) Influence of vesicle size, lipid composition and drug-to-lipid ratio on the
biological activity of liposomal doxorubicin in mice. Cancer Res. 49: 5922-5930.
Mendelsohn, R., Chen, H.C., Rerek, M.E., Moore, D.J. (2003) Infrared
microspectroscopic imaging maps the spatial distribution of exogenous molecules
in skin. J. Biomed. Opt. 8(2): 185-190.
Meyer, J.S. (1981) Growth and cell kinetic measurements in human tumors. Pathol.
Annu. 16: 53-81.
Mielke, S., Sparreboom, A., Mross, K. (2006) Peripheral neuropathy: A persisting
challenge in paclitaxel based regimes. Eur. J. Cancer 42(1): 24-30.
Miglietta, A., Roberta, C., Claudia, B., Gabriel, L., Gasco, M.R. (2002) Cellular uptake
and cytotoxicity of solid lipid nanospheres (SLN) incorporating doxorubicin or
paclitaxel. Int. J. Pharm. 210: 61-67.
Mishra, D., Garg, M., Dubey, V., Jain, S., Jain, N.K. (2007) Elastic liposomes mediated
transdermal delivery of an anti- hypertensive agent: propranolol hydrochloride. J.
Pharm. Sci. 96: 145-155.
Mishra, D., Mishra, P., Dubey, V., Dabadghao, S., Jain, N.K. (2007) Evaluation of uptake
and generation of immune response by murine dendritic cells pulsed with
hepatitis B surface antigen-loaded elastic liposomes. J. Vaccine 25: 6939-6944.
References
-292-
Mo, Y., Lim, L.-Y. (2005) Preparation and in vitro anticancer activity of wheat germ
agglutinin (WGA)-conjugated PLGA nanoparticles loaded with paclitaxel and
isopropyl myristate. J. Control. Release 107: 30-42.
Moore, D.J., Powis, G., Richardson, R.L., Pittelkow, M.R. (1985) Topical chemotherapy
of intradermal Walker 256 carcinosarcoma with diaziquone and doxorubicin in
the rat. Cancer Res. 45: 5466-5472.
Mu, L., Feng S.S. (2003) A novel controlled release formulation for the anticancer drug
Paclitaxel: PLGA nanoparticles containing Vitamin E TPGS. J. Control. Release
86: 33-48.
Mulik, R.S., Kulkarni, V.I., Murthy, R.S.R. (2009) chitosan based thermosensitive
hydrogel containing liposomes for sustained delivery of cytarabine. Drug. Dev.
Ind. Pharm. 35(1): 49-56.
Müller, R.H., Mäder, K., Gohla, S. (2000) Solid lipid nanoparticles (SLN) for controlled
drug delivery-a review of the state of the art. Eur. J. Pharm. Biopharm. 50: 161-
178.
Mura, A., Maestrelli, F., Gonzlez-Rodrguez, M.L., Michelacci, I., Ghelardini, C.,
Rabasco, A.M. (2007) Development, characterization and in vivo evaluation of
benzocaine-loaded liposomes. Eur. J. Pharm. Biopharm. 67(1): 86-95.
Nagase, Y., Hirata, M., Arima, H., Tajiri, S., Nishimoto, Y., Hiryama, R., Uekama, K.,
(2002) Protective effect of sulfobutylether β-cyclodextrins on DY-9760e-induced
hemolysis in vitro. J. Pharm. Sci. 91(11): 2382-2389.
Naha, P., Bhattacharya, K., Tenuta, T., Dawson, K., Lynch, I., Gracia, A., Lyng, F.,
Byrne, H. (2010) Intracellular localisation, geno- and cytotoxic response of poly
N-isopropylacrylamide (PNIPAM) nanoparticles to human keratinocyte (HaCaT)
and colon cells (SW 480). Toxi. Lett. 198(2): 134-143.
Naik, S., Patel, D., Chuttani, K., Mishra, A.K., Misra, A. (2012) In vitro mechanistic
study of cell death and in vivo performance evaluation of RGD grafted
References
-293-
PEGgylated docetaxel liposomes in breast cancer. Nanomed.: Nanotechnol. 8(6):
951-962.
Nair, L.S., Starness, T., Ko, J.W.R, Laurencin, C.T. (2007) Development of injectable
thermogelling chitosan-inorganic phosphate solutions for biomedical applications.
Biomacromolecules 8: 3779-3785.
Nair, V.B., Panchagnula, R. (2003) Effect of iontophoresis and fatty acids on permeation
of arginine vasopressin through rat skin. Pharmacol. Res. 47(6): 563-569.
Nassier, O. A. (2010) Protein undernutrition in tumor-bearing mice, response and toxicity
to paclitaxel. Int. J. Pharm. 6(3): 296-300.
Nava, G., Pinon, E., Mendoza, L., Mendoza, N., Quintanar, D., Ganem, A. (2011)
Formulation and in vitro, ex vivo and in vivo evaluation of elastic liposomes for
transdermal delivery of Ketorolac Tromethamine. Pharmaceutics 3: 954-970.
Nepal, O., Rao, J.P. (2011) Haemolytic effects of hypo-osmotic salt solutions on human
erythrocytes. Kathmandu. Univ. Med. J. 34(2): 35-39.
Nishiyama, N., Okazaki, S., Cabral, H., Miyamoto, M., Kato, Y., Sugiyama, Y. (2003)
Novel cisplatin-incorporated polymeric micelles can eradicate solid tumors in
mice. Cancer Res. 63: 8977-8983.
Nornoo, A.O., Osborne, D.W., Chow, S.L. (2008). Cremophor-free intravenous
microemulsions for paclitaxel I: formulation, cytotoxicity and hemolysis. Int. J.
Pharm. 349: 108-116.
Nsereko, S., Amiji, M. (2002) Localized delivery of paclitaxel in solid tumors from
biodegradable chitin microparticle formulations. Biomaterials 23: 2723-2731.
Obara, K., Ishihara, M., Ozeki, Y., Ishizuka, T., Hayashi, T., Nakamura, S., Saito, Y.,
Yura, H., Matsui, T., Hattori, H., Takase, B., Ishihara, M., Kikuchi, M
Maehara, T. (2005) Controlled release of paclitaxel from photocrosslinked
chitosan hydrogels and its subsequent effect on subcutaneous tumor growth in
mice. J. Control. Release 110: 79-89.
References
-294-
Okano, T., Bae, Y.H., Jacobs, H., Kim, S.W. (1990) Thermally on-off switching
polymers for drug permeation and release. J. Control. Release 11: 255-265.
Omelyanenko, V., Kopeckova, P., Gentry, C., Kopecek, J. (1998) Targetable HPMA
copolymer-adriamycin conjugates. Recognition, internalization and subcellular
fate. J. Control. Release 53: 25-37.
Ooya, T., Lee, J., Park, K. (2003) Effects of ethylene glycol-based graft, star-shaped, and
dendritic polymers on solubilization and controlled release of paclitaxel. J.
Control. Release 93: 121-127.
Ortiz, R., Jessie, L.S., Lu, A.Z., Gan, Y., Wientjes, M. (2007) Biodegradable intra
prostatic Doxorubicin implants. AAPS J. 9(2): E241-E250.
Pakunlu, R.I., Wang, Y., Saad, M., Khandare, J.J., Starovoytov, V., Minko, T. (2006) In
vitro and in vivo intracellular liposomal delivery of antisense oligonucleotides and
anticancer drug. J. Control. Release 114: 153-162.
Panayiotis, P., Constantinides, K.J., Tustian, A.K., Schneider, B., Lalji, S., Ma, W.,
Wentzel, B., Kessler, D., Worah, D., Quay, S.C. (2002) Formulation development
and antitumor activity of a filter sterilizable emulsion of paclitaxel. Pharm. Res.
17(2): 175-182.
Panchagnula, R. (1998) Pharmaceutical aspects of paclitaxel Int. J. Pharm. 172: 1-15.
Panchagnula, R., Desu, H., Jain, A., Khandavilli, S. (2004) Effect of lipid bilayer
alteration on transdermal delivery of a high molecular weight and lipophilic drug:
Studies with paclitaxel. J. Pharm. Sci. 93(9): 2177-2183.
Panchagnula, R., Desu, H., Jain, A., Khandavilli, S. (2005) Feasibility studies of dermal
delivery of paclitaxel with binary combinations of ethanol and isopropyl
myristate: role of solubility, partitioning and lipid bilayer perturbation. IL
Farmaco 60: 894-899.
Panchagnula, R., Salve, P.S., Thomas, N.S., Jain, A.K., Ramarao, P. (2001) Transdermal
delivery of naloxone: effect of water, propylene glycol, ethanol and their binary
combinations on permeation through rat skin. Int. J. Pharm. 219 (1-2): 95-105.
References
-295-
Panchagnula, R., Dhanikula, R.S., Dhanikula, A.B. (2006) An ex vivo characterization of
Paclitaxel loaded chitosan films after implantation in mice. Curr. Drug
Deliv. 3(3): 287-297.
Paolino, D., Celia, C., Trapasso, E., Cilurzo, F., Fresta, M. (2012) Paclitaxel-loaded
ethosomes: Potential treatment of squamous cell carcinoma, a malignant
transformation of actinic keratoses. Eur. J. Pharm. Biopharm. 81(1): 102-112.
Park, J.H., Chi, S.C., Lee, W.S., Lee, W.M., Koo, Y.B., Yong, C.S., Choi, H.G., Woo,
J.S. (2009) Toxicity studies of Cremophor-free paclitaxel solid dispersion
formulated by a supercritical anti solvent process. Arch. Pharm. Res. 32(1): 139-
148.
Park, J.H., Chi, S.C., Woo, J.S. (2008) Preparation and evaluation of paclitaxel solid
dispersion by supercritical anti-solvent process. J. Korean Pharm. Sci. 38(4):
241-247.
Park, Y.D., Tirelli, N., Hubbell, J.A. (2003) Photopolymerized hyaluronic acid-based
hydrogels and interpenetrating networks. Biomaterials 24: 893-900.
Paul, A., Cevc, G., Bachhawat B.K. (1995a) Transdermal immunization with large
proteins by means of ultra deformable drug carriers. Eur. J. Immunol. 25: 3521-
3524.
Paul, A., Cevc, G., Bachhawat, B. K. (1998) Transdermal immunisation with an integral
membrane component, gap junction protein, by means of ultradeformable drug
carriers, transfersomes. Vaccine 16(2-3): 188-195.
Perdue, J.D., Seaton, P.J., Tyrell, J.A., Devido, D.R. (2006) The removal of Cremophor®
EL from paclitaxel for quantitative analysis by HPLC-UV. J. Pharm. Biomed.
Anal. 41:117-123.
Perez, E.A. (1998) Paclitaxel in breast cancer. The Oncologist 3: 375-389.
Peter, S.J., Miller, S.T., Zhu, G.M., Yasko, A.W., Mikos, A.G. (1998) In vivo degradation
of a poly (propylene fumarate)/tricalcium phosphate injectable composite
scaffold. J. Biomed. Mater. Res. 41: 1-7.
References
-296-
Peters, M., Byod, E.M. (1967) The influence of a cachexigenic diet on caffeine toxicity.
Toxicology & Applied Pharmacology. 11(1):121-127.
Pinto Reis, C., Neufeld, R.J., Ribeiro, A.J., Veiga, F.I. (2006) Nanoencapsulation:
Methods for preparation of drug-loaded polymeric nanoparticles. Nanomedicine
2: 8-21.
Planas, M.E., Gonzalez, P., Rodriguez, L., Sanchez, S., Cevc, G. (1992) Noninvasive
percutaneous induction of topical analgesic by a new type of drug carrier and
prolongation of local pain insensitivity by anesthetic liposomes. Anesth. Analg.
75: 615-621.
Puri, R.,Jain, S. (2012) Ethogel topical formulation for increasing the local
bioavailability of 5-Flurouracil: A Mechanistic study. Anti cancer drugs
Qiu, Y., Gao, Y., Hu, K., Li, F. (2008) Enhancement of skin permeation of docetaxel: A
novel approach combining microneedle and elastic liposomes. J. Control. Release
129(2):144-150.
Rand, R.P., Parsegian, V.A. (1990) Hydration forces between phospholipid bilayers.
Biochim. Biophys. Acta. 988: 351-376.
Rane, S., Prabhakar, B. (2009) Influence of liposome composition on paclitaxel
entrapment and pH sensitivity of liposomes. Int. J. Pharmtech. Res. 1(3): 914-
917.
Ravichandiran, V., Masilamani, K., Senthilnathan, B. (2011) Liposome-A versatile drug
delivery system. Der Pharmacia Sinica 2(1): 19-30.
Reed, K.W., Yalkowsky, S.H. (1985) Lysis of human red blood cells in the presence of
various cosolvents. J. Parenter. Sci. Tech. 39: 64-69.
Ritschel, W.A., Panchagnula, R., Stemmer, K. and Asharaf, M. (1991) Development of
an intracutaneous depot for drugs. Skin Pharmacol. 4: 235-245.
Rodrigues, D.G., Maria, D.A., Fernandes, D.C., Valduga, C.J., Couto, R.D., Ibanez, O.C.
(2005) Improvement of paclitaxel therapeutic index by derivatization and
References
-297-
association to a cholesterol-rich microemulsion: in vitro and in vivo studies.
Cancer Chemother. Pharmacol. 55: 565-576.
Rotunda, A.M., Suzuki, H., Moy, R.L., Kolodney, M.S. (2004) Detergent effects of
sodium deoxycholate is a major feature of an injectable phosphatidylcholine
formulation used for localized fat dissolution. Dermatol. Surg. 30: 1001-1008.
Ruel-Gariepy, E., Chenite, A., Chaput, C., Guirguis. S., Leroux, J.C. (2000)
Characterization of thermosensitive chitosan gels for the sustained delivery of
drugs. Int. J. Pharm. 203: 89-98.
Ruel-Gariepy, E., Leclair, G., Hildgen, P., Gupta, A., Leroux, J.C. (2002)
Thermosensitive chitosan based hydrogel containing liposomes for the delivery of
hydrophillic molecules. J. Control. Release 82: 373-383.
Ruel-Gariepy, E., Matthew Shive, E., Bichara, A., Berrada, M., Garrec, D.L., Chenite,
A., Leroux, J.C. (2004) Thermosensitive chitosan-based hydrogel for the local
delivery of paclitaxel. Eur. J. Pharm. Biopharm. 57: 53-63.
Saad, S. Y., Ali, M. (1999) Effect of taxol on the expression of transforming growth
factor beta-1 in Ehrlich ascites carcinoma cells. Saudi Pharm. J. 7(4): 201-204.
Sahoo, K., Labhasetwar, V. (2003) Nanotech approaches to drug delivery and imaging.
Drug Discov. Today 8: 1112-1120.
Sapra, B., Jain, S., Tiwary, A.K. (2008) Transdermal delivery of carvedilol containing
glycyrrhizin and chitosan as permeation enhancers: Biochemical, biophysical,
microscopic and pharmacodynamic evaluation. Drug Delivery 15: 443-454.
Saville, M.W., Lietzau, J., Pluda, J.M., Wilson, W.H., Humphrey, R.W., Feigel, E.,
Steinberg, S.M., Broder, S. (1995) Treatment of HIV-associated Kaposi's sarcoma
with paclitaxel. Lancet 346 (8966): 26-28.
Schatzlein, A., Cevc, G. (1995) Skin penetration by phospholipid vesicles, transfersomes,
as visualized by means of confocal laser scanning microscopy, in: G. Cevc, F.
Paltauf (Eds.), Phospholipids: Characterization, metabolism and novel biological
applications, AOCS Press, Champaign. IL. 191-209.
References
-298-
Schimtt, S.M., Strieth, S., Krasnici, S., Sauer, B., Schulze, B., Tefil, M., Michaelis, U,
Naujoks, K., Dellian, M. (2003) Neovascular targeting therapy: paclitaxel
encapsulated in cationic liposomes improves antitumoral efficacy. Clin. Cancer.
Res. 2003 9(6):2335-2341.
Scong, H., Jang, M., Wientjus, G., Jessie, L. (2001) Determinants of paclitaxel uptake,
accumulation and retention in solid tumors. Invest. New Drugs 19: 113-123.
Scott, C.J., Marouf, W.M, Quinn, D. J., Buick, R.J., Orr, S.J., Donnelly, R.F., McCarron,
P.A. (2008). Immunological targeting of the endocytotic siglec-7 receptor using
peripheralnattachment of siglec-7 antibodies to poly(Lactide-co-Glycolide)
nanoparticles. Pharm. Res. 135-146.
Selvam, S., Mishra, A.K. (2008) Disaggregation of amphotericin B by sodium
deoxycholate micellar aggregates. J. Photochem. Photobio. 93: 66-70.
Serpe, L., Catalano, M.G., Cavalli, R., Ugazio, E., Bosco, O., Canaparo, R., Muntoni, E.,
Frairia, R., Gasco, M.R., Zara, G.P. (2004) Cytotoxicity of anticancer drugs
incorporated in solid lipid nanoparticles on HT-29 colorectal cancer cell line. Eur.
J. Pharm. Biopharm. 58: 673-680.
Shackney, S.E., McCormack, G.W., Cuchural Jr, G.J. (1978) Growth rate patterns of
solid tumors and their relation to responsiveness to therapy: an analytical review.
Ann. Intern. Med. 89: 107-121.
Shakeel, F., Ramadan, W. (2010) Transdermal delivery of anticancer drug caffeine from
water-in-oil nanoemulsions. Colloids and Surfaces B: Biointerfaces. 75: 356-
362.
Shao, Z., Mitra, A.K. (1992) Nasal membrane and intercellular protein and enzyme
release by bile salts and bile-fatty acid mixed micelle: correlation with facilitated
drug transport. Pharm. Res. 9: 1184-1189.
Shapira, A., Livney, Y.D., Broxterman, H.J., Assaraf, Y.G. (2011) Nanomedicine for
targeted cancer therapy: Towards the overcoming of drug resistsnce. Drug Resist
Updat. 14(3): 150-163.
References
-299-
Sharma, A., Mayhew, E., Straubinger, R.M. (1993) Anti-tumor effect of taxol-containing
liposomes in a taxol-resistant murine tumor model. Cancer Res. 53: 5877-5881.
Sheihet, L., Garbuzenko, O.B., Bushman, J., Gounder, M.K., Minko, T., Kohn, J. (2012)
Paclitaxel in tyrosine-derived nanospheres as a potential anti-cancer agent: In vivo
evaluation of toxicity and efficacy in comparison with paclitaxel in Cremophor.
Eur. J. Pharm. Sci. 45: 320-329.
Shenoy, D.B., Amiji, M.M. (2005) Poly(ethylene oxide)-modified poly(ethylene oxide-
caprolactone) nanoparticles for targeted delivery of tamoxifen in breast cancer.
Int. J. Pharm. 293: 261-270.
Shikani, A.H., Domb, A.J. (2000) Polymer chemotherapy for head and neck cancer.
Laryngoscope 110: 907-917.
Shikanov, A., Shikanov, S., Vaisman, B., Golenserc, J., Domb, A.J. (2008) Paclitaxel
tumor biodistribution and efficacy after intratumoral injection of a biodegradable
extended release implant. Int. J. Pharm. 358: 114-120.
Shim, W.S., Kim, J.H., Kim, K., Kim, Y.S., Park, R.W., Kim, I.S., Kwon, C., Lee, D.S.
(2007) pH- and temperature-sensitive, injectable, biodegradable block copolymer
hydrogels as carriers for paclitaxel. Int. J. Pharm. 331: 11-18.
Shimomura, T., Fujiwara, H., Ikawa, S., Kigawa, J., Terakawa, N. (1998) Effect of taxol
on blood cells. Lancet. 352: 541-542.
Singh, H., Utreja, P., Tiwary, A.K., Jain, S. (2009) Elastic liposomal formulation for
sustained delivery of colchicine: In vitro characterization and in vivo evaluation of
anti-gout activity. AAPS J. 11(1): 54-64.
Singhai, A.K., Jain, S., Jain, N.K. (1997) Evaluation of an aqueous injection of
ketoprofen. Pharmazie 52: 2149-2151.
Singla, A.K., Garg, A., Agarwal, D. (2002) Paclitaxel and its formulations. Int. J.
Pharm. 235: 179-192.
References
-300-
Soga, O., Nostrum, C.F., Rijcken, C.J., Schiffelers, R.M., Strom, G., Hennink, W.E.
(2005) Thermo sensitive and biodegradable polymeric micelles for paclitaxel
delivery. J. Control. Release 103: 341-353.
Sonnichsen, D.S., Relling, M.V. (1994) Clinical pharmacokinetics of paclitaxel. Clin.
Pharmacokinetics 27: 256-269.
Soo, P.L., Cho, J., Grant, J., Ho, E., Miller, M.P., Allen, C. (2008) Drug release
mechanism of paclitaxel from a chitosan-lipid implant system: Effect of swelling,
degradation and morphology. Eur. J. Pharm. Biopharm. 69: 149-157.
Souto, E.B., Müller, R.H (2009) Lipid nanoparticles-Effect on bioavailability and
pharmacokinetics changes, M. Schäfer-Korting, Editor, Handbook of
Experimental Pharmacology - Novel Drug Delivery Approaches, Vol.
197 Springer Verlag, Heidelberg, Berlin, Germany (2009), pp. 115-142 Chapter 4.
Souza, J. G., Gelfuso, G. M., Simao, P. S., Borges, A. C., Lopez, R. F. (2011)
Iontophoretic transport of zinc phthalocyanine tetrasulfonic acid as a tool to
improve drug topical delivery. Anticancer Drugs 22(8): 783-793.
Spratlin, J., Sawyer, M.B. (2007) Pharmacogenetics of paclitaxel metabolism. Crit. Rev.
Oncology. Hemat. 61: 222-229.
Sqadari, C.,Toschi, E., Palladino, C., Barrilari, G., Carlei, D., Cereseto, A., Ciccolella, C.,
Yarchoan, R., Monini, P., Stuzul, M. (2000) Mechanism of paclitaxel activity in
Kapsoi’s sarcoma. J. Immunol. 165(1):509-517.
Stewart, D.J. (2007) Mechanisms of resistance to cisplatin and carboplatin. Crit. Rev.
Oncol. Hematol. 63: 12-31.
Su, M., Zhao, M., Luo, Y., Lin, X., Xu, L., He, H., Xu, H., Tang, X. (2011) Evaluation of
the efficacy, toxicity and safety of vinorelbine incorporated in a lipid emulsion.
Int. J. Pharm. 411 (1-2): 188-196.
Sun, B., Ranganathan, B., Feng, S.S. (2008) Multifunctional poly(D,L- lactide-co-
glycolide)/montmorillonite PLGA/MMT nanoparticles decorated by Trastuzumab
for targeted chemotherapy of breast cancer. Biomaterials 29: 475-486.
References
-301-
Suppasansatorn, P., Nimmanni, U., Conwa, B.R., Lingran, D., Wan, Y (2007)
Microemulsion as topical delivery vehicles for the anti-melanoma prodrug,
temozolomide hexyl ester (TMZA-HE). J. Pharm. Pharmacol. 59(6): 787-794.
Szebeni, J., Muggia, F.M., Alving, C.R. (1998) Complement activation by cremophor EL
as a possible contributor to hypersensitivity to Paclitaxel an in vitro study. J. Nat.
Cancer. Inst. 90: 300-306.
Szoka, F., Papahadjopoulos, D. (1980) Comparative properties and methods of
preparation of lipid vesicles (liposomes). Annu.Rev.Biophys.Bioeng. 9: 467-508.
Szoka, F., Papahadjopoulos, D. (1980) Comparative properties and methods of
preparation of lipid vesicles (liposomes). Ann. Rev. Biophys. Bioeng. 9: 467-508.
Tahar, Y., Ishii, Y., (2001) Apatite cement containing cis-diaminedichloro platinum
implanted in rabbit femur for sustained release of anticancer drug and bone
formation. J. Orthop. Sci. 6(6): 556-565.
Tamm, L.K., Tatulian, S.A. (1997) Infrared spectroscopy of proteins and peptides in lipid
bilayers. Q. Rev. Biophys. 30(4): 365-429.
Tannock, I.F. (2001) Tumor physiology and drug resistance. Cancer Meta. Rev.20: 123-
132.
Teskac, K., Kristi, J. (2010) The evidence for solid lipid nanoparticles mediated cell
uptake of Resveratrol. Int. J. Pharm. 390(1): 61-69.
Thein-Han, W.W., Steven, W.F. (2004) Transdermal delivery controlled by chitosan
membrane. Drug Dev. Ind. Pharm. 30(4): 397-404.
Torchilin, V.P. (2005) Fluorescence microscopy to follow the targeting of liposomes and
micelles to cell and their intracellular fate. Adv. Drug Deliv. Rev. 57: 95-109.
Trotta, M., Peira, E., Carlotti, M.E., Gallarate, M. (2002) Elastic liposomes for skin
delivery of dipotassium glycyrrhizinate. Int. J. Pharm. 241: 319-327.
References
-302-
Tsallas, A., Jackson, J., Burt, H. (2011) The uptake of paclitaxel and docetaxel into ex
vivo porcine bladder tissue from polymeric micelle formulations. Cancer
Chemother. Pharmacol. 68(2): 431-444.
Urbinati, G., Marsaud, V., Plassat, V., Fattal, E., Lesieur, S., Michel, J. (2010) Renoir
liposomes loaded with histone deacetylase inhibitors for breast cancer therapy.
Int. J. Pharm. 397(1-2): 184-193.
Utreja, P., Jain, S., Tiwary, A.K. (2011) Localized delivery of paclitaxel using elastic
liposomes: Formulation development and evaluation. Drug Deliv. 18(5): 367-376.
Vanden Bergh B.A., Bouwstra J.A., Junginger, H.E., Wertz, P.W. (1999) Elasticity of
vesicles affects hairless mouse skin structure and permeability. J. Control.
Release 62: 367-379.
Vanden Bergh, B.A., Salomons-de-Vries, I., Bouwstra, J.A. (1998) Interaction between
liposomes and human stratum corneum studied by freeze-substitution electron
microscopy. Int. J. Pharm. 167: 57-67.
Vanden Bergh, B.A., Wertz, P.W., Junginger, H.E., Bouwstra, J.A. (2001) Elasticity of
vesicles assessed by electron spin resonance, electron microscopy and extrusion
measurements. Int. J. Pharm. 217: 13-24.
Van-Kuijk, M.E.M.J., Junginger, H.E., Bouwstra, J.A. (1998) Interaction between
liposomes and human skin in vitro, a confocal laser scanning microscopy study.
Biochem. Biophy. Acta. 1022:171-180.
Varma, M.V.S., Panchagnula, R. (2005) Enhanced oral paclitaxel absorption with
vitamin E-TPGS: Effect on solubility and permeability in vitro, in situ and in vivo.
Eur. J. Pharm. Sci. 25: 445-453.
Vasir, K., Reddy, M.K., Labhasetwar, V. (2005) Nanosystems in drug targeting:
opportunities and challenges. Curr. Nanosci. 1: 47-64.
Verma, D.D., Verma, S., Blume, G., Fahr, A. (2003) Particle size of liposomes influences
dermal delivery of substances into skin. Int. J. Pharm. 258: 141-151.
References
-303-
Vodovozova, E.L., Kuznetsova, N.R., Gaenko, G.P., Molotkovsky, J.G. (2007)
Liposomal formulation of a methotrexate diglyceride conjugate: Activity toward a
culture of methotrexate-resistant leukemia cells. Russian J. Bioorg. Chem. 33(4):
436-438.
Wang, C., Wang, Y.J., Fan, M., Luo, F., Qian, Z. (2011a) Characterization,
pharmacokinetic and disposition of novel nanoscale preparations of paclitaxel.
Int. J. Pharm. 414(1-2): 251-259.
Wang, S., Shanga, D., Lia, X., Jianga, T. (2009) Preparations and properties of
hydroxycamptothecin emulsion and its tissue distribution in mice. Asian J.
Pharm. Sci. 4(5): 299-307.
Wang, Y., Wu, K.C., Zhao, B.X., Zhao, X., Wang, X., Chen, S., Nie, S.F., Pan, W.F.,
Zhang, X., Zhang, Q. (2011b) Novel paclitaxel microemulsion containing a
reduced amount of Cremophor EL: Pharmacokinetics, biodistribution, and in vivo
antitumor efficacy and safety. J. Biomed. Biotechnol. (doi:10.1155/2011/854872)
Wani, M.C., Tylor, H.L., Wall, M.E., Coggon, P., Mcphail, A.T. (1971) Plant antitumor
agents. VI. The isolation and structure of taxol, a novel antileukemic and
antitumor agent from texus brevifolia. J. Am. Chem. Soc. 93: 2325-2327.
Watkins, J. (1979) Anaphylactic reactions to i.v. substances. J. Anaesth. 51: 51-60.
Wei., Z., Hao, J., Yuan, S., Li, Y., Juan, W., Sha, X., Fang, X. (2009) Paclitaxel-loaded
pluronic p123/F127 mixed polymeric micelles: Formulation, optimization and in
vitro characterization. Int. J. Pharm. 276: 176-185.
Weiss, R.B., Donehower, R.C., Wiernik, P.H., Ohnuma, T., Gralla, R.L., Trump, D.,
Baker, R., Vanecho, D.A., Vonhoff, D.D., Leyland-Jones, B. (1990)
Hypersensitivity reactions from taxol. J. Clin. Oncol. 8: 1263-1268.
Weitong, S., Zhang, N., Li, A., Zou, W., Xu, W. (2008) Preparation and evaluation of
N3-O toluyl-fluorouracil-loaded liposomes. Int. J. Pharm. 353: 243-250.
Wissing, S.A., Kayser, O., Muller, R.H. (2004) Solid lipid nanoparticles for parenteral
drug delivery. Adv. Drug Deliv. Rev. 56: 1257-1272.
References
-304-
Wolinsky, J.B., Colson, Y.L., Grinstaff, M.W (2012) Local drug delivery strategies for
cancer treatment: Gels, nanoparticles, polymeric films, rods, and wafers. J.
Control. Release 159 (1): 14-16.
Wu, J., Su, Z.G., Ma, G.H. (2006) A thermo- and pH sensitive hydrogel composed of
quaternized chitosan/glycerophosphate. Int. J. Pharm. 315: 1-11.
Xiao, W., Luo, J Jain, T., Riggs, J.W., Teseng, H.P., Henderson, P.T., Cherry, S.R.,
Rowland, D., Lam, K.S. (2012) Biodistribution and pharmacokinetics of
telodendrimer micellar paclitaxel nanoformulation in a mouse xenografts model
of ovarian cancer. Int. J. Nano medicine 7:1585-1597.
Xua, Z., Gu, W., Huang, J., Sui, H., Zhou, Z. Yang,Y., Yan, Z., Li, Y. (2005) In vitro and
in vivo evaluation of actively targetable nanoparticles for paclitaxel delivery. Int.
J. Pharm. 288: 361-368.
Yanasarn, N., Sloat, B.R., Cui, Z. (2009) Nanoparticles engineered from lecithin-in-water
emulsions as a potential delivery system for docetaxel. Int. J. Pharm. 379: 174-
180.
Yang, T., Choi, M.K., Cuia, F.D., Kim, J.S., Chung, S.J., Shim, C.K., Kim, D.D.
(2007b) Preparation and evaluation of paclitaxel-loaded PEGylated
immunoliposome. J. Control. Release 120: 169-177.
Yang, T., Cui, F.D., Choi, M.K., Cho, J.W., Chung, S.J., Shim, C.K., Kim, D.D. (2007)
Enhanced solubility and stability of PEGylated liposomal paclitaxel: In vitro and
in vivo evaluation. Int. J. Pharm. 338: 317-326.
Yang, T., Cui, F.D., Choi, M.K., Lin, H., Chung, S.-J., Shim, C.-K., Kim, D.-D. (2007a)
Liposome formulation of paclitaxel with enhanced solubility and stability. Drug
Deliv. 14: 301-308.
Yann, H., Miao, J., Du, Y.Z., You, J., Hu, F.Q., Zeng, S. (2008) Cellular uptake of solid
lipid nanoparticles and cytotoxicity of encapsulated paclitaxel in A549 cancer
cells. Int. J. Pharm. 348: 137-145.
References
-305-
Yoshizawa, Y., Kono, Y., Ogawara, K.I., Kimura, T., Higaki, K. (2011) PEG
liposomalization of paclitaxel improved its in vivo disposition and anti-tumor
efficacy. Int. J. Pharm. 412: 132-141.
Zaafarany, G.M., Awad, G.A., Holayel, S.M., Mortada, N.D. (2010) Role of edge
activators and surface charge in developing ultradeformable vesicles with
enhanced skin delivery. Int. J. Pharm. 397(1-2): 164-172.
Zahr, A.S., Pishko, M.V. (2007) Encapsulation of paclitaxel in macromolecular
nanoshells. Biomacromolecules 8: 2004-2010.
Zeljka Pavelic, Z., Basnet, N.S., Schubert, R. (2001) Liposomal gels for vaginal drug
delivery. Int. J. Pharm. 219(1-2): 139-149.
Zellmer, S., Pfeil, W., Lasch, J. (1995) Interaction of phosphatidyl choline liposomes
with the human stratum corneum. Biochim. Biophy. Acta 1237: 176-182.
Zhang, A., J., Xuan, T., Parmar, M., Ma, L., Ugwu, S., Ali, S., Ahmad, I. (2004)
Development and characterization of a novel liposome-based formulation of SN-
38. Int. J. Pharm. 270: 93-107.
Zhang, H., Wang, Z.Y., Gong, W., Li, Z.P., Mei , X.G., Lv, W.L. (2011) Development
and characteristics of temperature-sensitive liposomes for vinorelbine bitartrate.
Int. J. Pharm. 414(1-2): 56-62.
Zhang, J. Q., Zhang, Z.R., Yang, H., Tan, Q.Y., Qin, S.R., Qiu, X.L. (2005) Lyophilized
paclitaxel magnetoliposomes as a potential drug delivery system for breast
carcinoma via parenteral administration: in vitro and in vivo studies. Pharm. Res.
22(4): 573-583.
Zhang, W., Junguo, H., Yuan, S., Li, Y., Juan, W., Sha, X., Fang, X. (2009) Paclitaxel-
loaded pluronic P123/F127 mixed polymeric micelles: formulation, optimization
and in vitro characterization. Int. J. Pharm. 376: 176-185.
Zhang, Z., Feng S.S. (2007) The drug encapsulation efficiency, in vitro drug release,
cellular uptake and cytotoxicity of paclitaxel-loaded poly(lactide)-tocopheryl
polyethylene glycol succinate nanoparticles. Biomaterials 27: 4025-4033.
References
-306-
Zhao, Q.H., Zhang, Y., Liu, Y., Li, H., Shen, W.Y., Yang, W.J., Wen, L.P. (2010)
Anticancer effect of realgar nanoparticles on mouse melanoma skin cancer in vivo
via transdermal drug delivery. Med. Oncol. 27 (2): 203-212.
Zhenghong, X., Lingli, C., Wangwen, G., Gao, U.,. Liping, L., Zhang, Z., Li, Y. (2009)
The performance of docetaxel-loaded solid lipid nanoparticles targeted to
hepatocellular carcinoma. Biomaterials 30: 226-232.
Zhou, H.Y., Chen, X.G., Kong, M., Liu, L.C. (2009) Preparation of chitosan-based
thermosensitive hydrogel for drug delivery. J. Appl. Polym. Sci. 112: 1509-1515.
Websites:
www.rnspeak.com/pathophysiology/cancer
Wikipedia (http://en.wikipedia.org/wiki/Paclitaxel) accessed on May 2012.