Chapter 5 Outline
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Transcript of Chapter 5 Outline
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Chapter 5 Outline
• 5.1 Dominance Is Interaction between Genes at the Same Locus, 100
• 5.2 Penetrance and Expressivity Describe How Genes Are Expressed as Phenotype, 102
• 5.3 Lethal Alleles May Alter Phenotypic Ratios, 103
• 5.4 Multiple Alleles at a Locus Create a Greater Variety of Genotypes and Phenotypes than Do Two Alleles, 103
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Chapter 5 Outline
• 5.5 Gene Interaction Occurs When Genes at Multiple Loci Determine a Single Phenotype, 105
• 5.6 Sex Influences the Inheritance and Expression of Genes in a Variety of Ways, 114
• 5.7 Anticipation Is the Stronger or Earlier Expression of Traits in Succeeding Generations, 122
• 5.8 The Expression of a Genotype May Be Influenced by Environmental Effects, 122
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5.1 Dominance Is Interaction between Genes at the Same Locus
• Genes at the same locus – two versions of the same gene; each version of the same gene is defined as allele.
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5.1 Dominance Is Interaction between Genes at the Same Locus
• Incomplete dominance
• Codominance
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• Penetrance: percentage of individuals having a particular genotype that express the expected phenotype
• Expressivity: the degree to which a character is expressed
5.2 Penetrance and Expressivity Describe How Genes Are Expressed as Phenotype
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5.3 Lethal Alleles May Alter Phenotypic Ratios
• A lethal allele: causes death at an early stage of development, and so some genotypes may not appear among the progeny
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More than 2 alleles at a locus
•Relationship between allele pairs determines outcome
•Could be exhibited as dominant/recessive relationship as in duck feathers
•Could be exhibited in codominance as in ABO blood type
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5.4 Multiple Alleles at a Locus Create a Greater Variety of Genotypes and Phenotypes than Do Two Alleles
• ABO blood group
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5.5 Gene Interaction Occurs When Genes at Multiple Loci Determine a Single Phenotype
• Gene interaction: Effects of genes at one locus depend on the presence of genes at other loci.
• Gene interaction that produces novel phenotypes
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5.5 Gene Interaction Occurs When Genes at Multiple Loci Determine a Single Phenotype
• Gene interaction with epistasis
• Epistasis: One gene masks the effect of another gene.
• Recessive epistasis
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5.5 Gene Interaction Occurs When Genes at Multiple Loci Determine a Single Phenotype
• Dominant epistasis
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5.5 Gene Interaction Occurs When Genes at Multiple Loci Determine a Single Phenotype
• Duplicate recessive epistasis
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5.5 Gene Interaction Occurs When Genes at Multiple Loci Determine a Single Phenotype
• Complementation: determines whether mutations are at the same locus or at different loci
• The complex genetics of coat color in dogs:• Agouti (A) locus• Black (B) locus• Extension (E) locus• Spotting (S) locus
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5.6 Sex Influences the Inheritance and Expression of Genes in a Variety of Ways
• Sex-influenced and sex-limited characteristics
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Sex-influenced and sex-limited characteristics
• Sex-influenced characteristics
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Sex-influenced and sex-limited characteristics
• Sex-limited characteristics
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Sex-influenced and sex-limited characteristics
• Cytoplasmic inheritance
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Sex-influenced and sex-limited characteristics
• Genetic maternal effect
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Sex-influenced and sex-limited characteristics
• Genomic imprinting: differential expression of genetic material depending on whether it is inherited from the male or female parent
• Epigenetics: phenomena due to alterations to DNA that do not include changes in the base sequence; often affects the way in which the DNA sequences are expressed
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5.7 Anticipation Is the Stronger or Earlier Expression of Traits in Succeeding Generations
• Anticipation: A genetic trait becomes more strongly expressed or is expressed at an earlier stage as it is passed from generation to generation.
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5.8 The Expression of a Genotype May Be Influenced by Environmental Effects
• Temperature-sensitive allele: an allele whose product is functional only at a certain temperature
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