Chapter 4 Nucleic Acids and the RNA World. Key Concepts Nucleotides consist of a sugar, a phosphate...

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Chapter 4 Nucleic Acids and the RNA World

Transcript of Chapter 4 Nucleic Acids and the RNA World. Key Concepts Nucleotides consist of a sugar, a phosphate...

Page 1: Chapter 4 Nucleic Acids and the RNA World. Key Concepts Nucleotides consist of a sugar, a phosphate group, and a nitrogen-containing base. Ribonucleotides.

Chapter 4Nucleic Acids and the RNA World

Page 2: Chapter 4 Nucleic Acids and the RNA World. Key Concepts Nucleotides consist of a sugar, a phosphate group, and a nitrogen-containing base. Ribonucleotides.

Key Concepts

• Nucleotides consist of a sugar, a phosphate group, and a nitrogen-containing base. Ribonucleotides polymerize to form RNA. Deoxyribonucleotides polymerize to form DNA.

• DNA’s primary structure consists of a sequence of nitrogen-containing bases. Its secondary structure consists of two DNA strands, running in opposite directions, that are held together by complementary base pairing and twisted into a double helix. DNA structure allows organisms to store and replicate the information needed to grow and reproduce.

Page 3: Chapter 4 Nucleic Acids and the RNA World. Key Concepts Nucleotides consist of a sugar, a phosphate group, and a nitrogen-containing base. Ribonucleotides.

Key Concepts, cont’d

• RNA’s primary structure consists of a sequence of nitrogen-containing bases. Its secondary structure includes short regions of double helices and structures called hairpins.

• Because RNA molecules can carry information as well as catalyze chemical reactions, it is likely that RNA was the first self-replicating molecule and a forerunner to the first life-form.

Page 5: Chapter 4 Nucleic Acids and the RNA World. Key Concepts Nucleotides consist of a sugar, a phosphate group, and a nitrogen-containing base. Ribonucleotides.

RNA Structure & the Origin of Life

http://www.nature.com/scitable/content/rna-has-a-primary-and-secondary-structure-105312

http://exploringorigins.org/rnaworld.html

Page 6: Chapter 4 Nucleic Acids and the RNA World. Key Concepts Nucleotides consist of a sugar, a phosphate group, and a nitrogen-containing base. Ribonucleotides.

Website Questions(send questions to [email protected])

1. Describe 3 structural differences between DNA and RNA.

2. Describe 1 functional difference between DNA and RNA.

3. What is a ribozyme? How is it similar AND different than an enzyme?

4. Why do scientists say that RNA was important in the creation of life on earth?