Chapter 20 - Coordination in Mammals (Part 1)

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    CHAPTER 20

    COORDINATION

    20.1 NERVOUS SYSTEM

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    SUB-TOPIC

    20.1 Nervous system

    20.2 Mechanism of muscle contraction20.3 Hormones in mammals

    20.4 Hormones in plants

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    OBJECTIVES

    (a)Describe the organization of the nervous

    system.

    (b)Explain the general role of the sympathetic

    and parasympathetic nervous system.

    (c) Explain the generation of action potential,transmission and characteristic of nerve

    impulse along an axon.

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    OBJECTIVES

    (d)Describe the structure of synapse and

    explain the mechanism of synaptic

    transmission across synapses.

    (e)Compare the transmission of impulse at the

    synapse and along the axon.

    (f) Explain the mechanism of action of drugs on

    the nervous system.

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    The basic unit of the nervous systemneuron

    Dendrites receive stimuli

    Nerve cell body

    @ nucleus transmits thestimuli

    Axon transmits the impulse toanother dendrite

    PRIOR KNOWLEDGE :

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    Sensory neurons or receptors receive a stimulus from:

    ears - hearing

    eyes - sight

    nose - smell

    skin - touch

    mouth - taste

    PRIOR KNOWLEDGE :

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    Can be found inside my head. Makes my body work.

    Makes me think and feel.

    Makes sure our hearts keep beating and our

    lungs keep working without us having to think

    about it.

    Part of it makes our muscles work. The biggestpart of it makes us think, see, hear, feel and taste.

    Answer:

    Brain

    PRIOR KNOWLEDGE :

    What is it?

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    We each have a backbone, called a spine.

    It can be found in the spine.

    It joins the brain at the top of our neck.

    All through our body there are nerves which connectto it. This is called the nervous system.

    Messages from the nerves travel to it, which sends

    them to the brain. Neurons are long, wiry cells that carry

    electrical messages through the nervous system and thebrain.

    Answer:

    Spinal cord

    PRIOR KNOWLEDGE :

    What is it?

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    9/46The Nervous SystemThe Nervous System

    THE ORGANIZATION OF

    THE NERVOUS SYSTEM

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    The Nervous SystemThe Nervous System

    THE ORGANIZATION OF THE

    NERVOUS SYSTEM

    Central NervousSystem (CNS)

    Central NervousSystem (CNS)

    Peripheral NervousSystem (PNS)

    Peripheral NervousSystem (PNS)

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    Central Nervous System(CNS)

    Central Nervous System(CNS)

    BrainBrain Spinal CordSpinal Cord

    Peripheral Nervous System (PNS)Peripheral Nervous System (PNS)

    The Nervous SystemThe Nervous System

    THE ORGANIZATION OF

    THE NERVOUS SYSTEM

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    Central Nervous System(CNS)

    Central Nervous System(CNS)

    BrainBrain Spinal CordSpinal Cord

    Peripheral Nervous System (PNS)Peripheral Nervous System (PNS)

    The Nervous SystemThe Nervous System

    THE ORGANIZATION OF

    THE NERVOUS SYSTEM

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    Central NervousSystem (CNS)

    Central NervousSystem (CNS)

    BrainBrain Spinal CordSpinal Cord

    Peripheral NervousSystem (PNS)

    Peripheral NervousSystem (PNS)

    SensoryNeurons

    SensoryNeurons

    Motor NeuronsMotor Neurons

    The Nervous SystemThe Nervous System

    THE ORGANIZATION OF

    THE NERVOUS SYSTEM

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    Central Nervous System(CNS)

    Central Nervous System(CNS)

    BrainBrain Spinal CordSpinal Cord

    Peripheral Nervous System (PNS)Peripheral Nervous System (PNS)

    Sensory NeuronsSensory NeuronsMotor NeuronsMotor Neurons

    The Nervous SystemThe Nervous System

    THE ORGANIZATION OF

    THE NERVOUS SYSTEM

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    Central NervousSystem (CNS)

    Central NervousSystem (CNS)

    BrainBrain Spinal CordSpinal Cord

    Peripheral NervousSystem (PNS)

    Peripheral NervousSystem (PNS)

    SensoryNeurons

    SensoryNeurons

    Motor NeuronsMotor Neurons

    Somatic NervousSystem

    (voluntary)

    Somatic NervousSystem(voluntary)

    Autonomic NervousSystem

    (involuntary)

    Autonomic NervousSystem(involuntary)

    The Nervous SystemThe Nervous System

    THE ORGANIZATION OF

    THE NERVOUS SYSTEM

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    Central Nervous System(CNS)

    Central Nervous System(CNS)

    BrainBrain Spinal CordSpinal Cord

    Peripheral Nervous System (PNS)Peripheral Nervous System (PNS)

    Sensory NeuronsSensory NeuronsMotor NeuronsMotor Neurons

    Somatic Nervous System(voluntary)

    Somatic Nervous System(voluntary)

    Autonomic NervousSystem (involuntary)

    Autonomic NervousSystem (involuntary)

    The Nervous SystemThe Nervous System

    THE ORGANIZATION OF

    THE NERVOUS SYSTEM

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    Central NervousSystem (CNS)

    Central NervousSystem (CNS)

    BrainBrain Spinal CordSpinal Cord

    Peripheral NervousSystem (PNS)

    Peripheral NervousSystem (PNS)

    SensoryNeurons

    SensoryNeurons

    Motor NeuronsMotor Neurons

    Somatic NervousSystem

    (voluntary)

    Somatic NervousSystem(voluntary)

    Autonomic NervousSystem

    (involuntary)

    Autonomic NervousSystem(involuntary)

    Sympathetic

    Division

    Sympathetic

    Division

    Parasympathetic

    Division

    Parasympathetic

    Division

    The Nervous SystemThe Nervous System

    THE ORGANIZATION OF THE

    NERVOUS SYSTEM

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    A General

    Sense thepathway of the

    nervous system

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    THE NERVOUS SYSTEM

    Made up of highly specialized cells whose

    function is to:

    Receive stimuli

    Convert the stimuli into electrical

    impulses

    Transmit the impulses

    to

    Receptors

    Transduction

    Effectors

    Objective:

    (a) Describe the organization of the nervous system

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    Sensory input

    Brain & spinal cord

    Motor input

    Peripheral nervous

    system (PNS)

    Central nervous

    system (CNS)

    Sensory receptor

    Effector

    Motor neuron Sensory neuron

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    THE NERVOUS SYSTEM

    Receives & processes

    information

    Initiates action

    Consist of:Brain

    Spinal cord

    Central NervousSystem (CNS)Central NervousSystem (CNS)

    Objective:(a) Describe the organization of the nervous system

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    Outside of the brain and

    spinal cord

    Transmit signals between

    CNS & the rest of the body

    Peripheral Nervous

    System (PNS)

    Peripheral Nervous

    System (PNS)

    Objective:

    (a) Describe the organization of the nervous system

    THE NERVOUS SYSTEM

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    Can be divided into:.

    Conducts impulses from receptors to the CNS

    Informs the CNS of the state of the body interior

    and exterior

    .

    Conducts impulses from CNS to effectors(muscles/glands)

    Sensory Neuron

    Motor Neuron

    Objective:

    (a) Describe the organization of the nervous system

    Peripheral Nervous System(PNS)

    Peripheral Nervous System(PNS)

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    Figure 28.1B

    Brain

    1 Sensoryreceptor 2 Sensory neuron

    3

    4

    Ganglion

    Motorneuron Spinal

    cord

    Interneuron

    CNSNerve

    PNS

    Quadricepsmuscles

    Flexormuscles

    Objective:

    (a) Describe the organization of the nervous system

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    Divided into:

    .Controls voluntary movements

    Activates skeletal muscles

    Motor NeuronsMotor Neurons

    Somatic Nervous System

    Objective:

    (a) Describe the organization of the nervous system

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    .

    Controls involuntary responses

    Heart rate, peristalsis, sweating, respiration

    Actions are controlled in the medulla and the

    hypothalamus in the brain

    Influences organs, glands, & smooth muscles

    Autonomic Nervous System

    Objective:

    (a) Describe the organization of the nervous system

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    Consist of 2 types of neurons:

    Preganglionic neuronCell body in CNS

    MyelinatedProjects to the autonomic ganglion

    Postganglionic neuronCell body in autonomic ganglionUnmyelinatedProjects to the effector

    Autonomic Nervous SystemAutonomic Nervous System

    Clusters of

    neurons

    Objective:

    (a) Describe the organization of the nervous system

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    2 divisions:

    Sympathetic

    Fight or flight

    Energetic and

    stressful activities

    Primes body for

    intense skeletal

    muscle activity

    Autonomic Nervous SystemAutonomic Nervous System

    Objective:

    (b) Explain the general role of the sympathetic and parasympathetic nervous system.

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    Parasympathetic

    Rest and digest

    Leisure and

    maintenance activitiesDigestion, defecation,

    and diuresis

    Objective:

    (b) Explain the general role of the sympathetic and parasympathetic nervous system.

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    A t i ti

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    Antagonistic

    Control

    Both act on the sametarget but often giveantagonist effect

    Eg: heart rate

    Sympathetic stimulation causes

    HR to increase

    Parasympathetic stimulation

    causes HR to decrease

    http://d/My%20Documents/Downloads/D:/10.Coordination/Animation/autonomicns.swf
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    Figure 28.13

    PARASYMPATHETIC DIVISION SYMPATHETIC DIVISION

    Brain

    Constrictspupil

    Stimulatessalivaproduction

    Constrictsbronchi

    Slowsheart

    Stimulatesstomach,pancreas,and intestines

    Stimulatesurination

    Promoteserection ofgenitals

    Spinalcord

    Eye

    Salivaryglands

    Lung

    Heart

    LiverStomach

    Adrenal

    gland

    Pancreas

    Intestines

    Bladder

    Genitals

    Dilatespupil

    Inhibitssalivaproduction

    Relaxesbronchi

    Acceleratesheart

    Stimulatesepinephrineand norepi-nephrine release

    Stimulatesglucoserelease

    Inhibits

    stomach,pancreas,and intestines

    Inhibitsurination

    Promotes ejacu-lation and vaginalcontractions

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    SUMMARY:

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    PRIOR KNOWLEDGE :

    Sensory receptors are in sense organs, such as eyes, ears, mouth,nose, skin and different regions of the brain respond todifferent signals.

    Sensory neurons carry messages toward the CNS from sensoryreceptorsall over body.

    Sensory receptorsact as energy transducers. A transducer is a

    device for converting a non-electrical signal into an electricalone. In this case, the electrical signal produced is the actionpotential of a nerve.

    Objective:

    (c) Explain the generation of action potential, transmission and characteristic of nerveimpulse along an axon.

    http://d/My%20Documents/Downloads/D:/10.Coordination/Animation/actionpotential.swf
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    THE GENERATION OF NERVE RESTING

    POTENTIAL AND ACTION POTENTIAL

    All living cells have an electrical charge

    difference across their cell surface membrane

    Due to the difference in the concentration of ions

    on the outside and inside of a cell

    Known as

    Membrane Potential

    Objective:

    (c) Explain the generation of action potential, transmission and characteristic of nerve

    impulse along an axon.

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    Depends on the ionic gradients exist across the

    plasma membrane of the neuron

    Develops when the charge is more negative withinthe cell than from the outside

    The voltage measured across the plasma membraneis about -70 mV

    Resting Potential

    The membrane potential

    of a neuron that is nottransmitting signals

    Objective:

    (c) Explain the generation of action potential, transmission and characteristic of nerveim ulse alon an axon.

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    Resting potential is caused by the cell

    membranes ability to maintain

    a +ve charge

    on its OUTER surface

    a -ve charge

    on its INNER(cytoplasmic) surface

    Plasmamembrane

    Microelectrodeinside cell

    Axon

    Neuron

    Microelectrodeoutside cell

    Voltmeter

    70 mV

    Objective:

    (c) Explain the generation of action potential, transmission and characteristic of nerveim ulse alon an axon.

    Resting Potential

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    Inside the neurons,

    Higher K+

    ions concentrationLower Na+ ions concentration

    Outside the neurons,

    Higher Na+ ions concentration

    Lower K+ ions concentration

    Objective:

    (c) Explain the generation of action potential, transmission and characteristic of nerveim ulse alon an axon.

    Resting Potential

    The membrane potential

    of a neuron that is nottransmitting signals

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    Resting potential is generated and

    maintained with help from

    Active transportSodium-potassium pumpsPump K+ into the cell and Na+ out of the cell

    OUTSIDE OF CELL

    Na+

    Na+

    channel

    Na+ Na+Na+

    Na+K+ K+

    Na+

    Na+

    Na+

    Na+

    Na+

    K+Plasmamembrane

    Protein

    Na+

    K+

    K+

    K+

    K+

    K+ K+

    K+

    K+K+

    K+

    Na+ - K+pump

    Na+

    Na+

    K+

    channel

    INSIDE OF CELL

    Objective:

    (c) Explain the generation of action potential, transmission and characteristic of nerveim ulse alon an axon.

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    Passive transport (diffusion)

    Passive ions channels (Na+ and K+)OUTSIDE OF CELL

    Na+

    Na+

    channel

    Na+Na+

    Na+

    Na+K+ K+

    Na+

    Na+

    Na+

    Na+

    Na+

    K+Plasmamembrane

    Protein

    Na+

    K+

    K+

    K+

    K+

    K+ K+

    K+

    K+K+

    K+

    Na+ - K+pump

    Na+

    Na+

    K+channel

    INSIDE OF CELL

    Objective:

    (c) Explain the generation of action potential, transmission and characteristic of nerveim ulse alon an axon.

    http://d/My%20Documents/Downloads/D:/10.Coordination/Animation/nerve05.swf
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    Passive K+ ion channel

    Most common type of passive ion channel

    Neuron membrane is highly permeable to K+ ionsPassively diffuse out according to the

    concentration gradient

    Potassium ion pumped into (active transport) the

    neuron can diffuse out

    Objective:

    (c) Explain the generation of action potential, transmission and characteristic of nerveim ulse alon an axon.

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    Passive Na+ ion channel

    Allows a slow diffusion of Na+ ions into the membrane

    Permeability to Na+ ions is lower than to the K+ ions

    Na+ ions pumped out of the neuron cannot easily pass back

    into the cell

    This results in the resting potential condition or the :

    POLARIZATION STAGE

    Objective:

    (c) Explain the generation of action potential, transmission and characteristic of nerveim ulse alon an axon.

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    During resting potential:

    Sodium-potassium pump

    Pump Na+ out and K+ in actively

    Passive ions channels

    Pumps more K+ out than Na+ passively

    Voltage-gated ions channels CLOSED

    Objective:

    (c) Explain the generation of action potential, transmission and characteristic of nerveim ulse alon an axon.

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    Figure 28.4

    Resting state: voltage gated Na+

    and K+ channels closed; resting

    potential is maintained.

    1

    2

    3

    4

    A stimulus opens some Na+

    channels; if threshold is reached,

    action potential is triggered.

    Additional Na+ channels open,

    K+ channels are closed; interior of

    cell becomes more positive.

    5 The K+ channels close

    relatively slowly, causing

    a brief undershoot.

    Na+ channels close and

    inactivate. K+ channels

    open, and K+ rushes

    out; interior of cell more

    negative than outside.

    Neuron

    interior

    Actionpotential

    Thresholdpotential

    Resting potential

    1

    2

    3

    4

    5

    Na+

    Na+

    Na+

    Na+

    1 Return to resting state.

    1

    Neuron

    interior

    K+

    K+NEXT LECTURE