CHAPTER 11 CELL COMMUNICATION - Florida Gulf...
Transcript of CHAPTER 11 CELL COMMUNICATION - Florida Gulf...
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CHAPTER 11 CELL COMMUNICATION
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Figure 11.0 Yeast
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OVERVIEW OF CELL SIGNALING
• YEAST CELLS AND MATING.
• A AND ALPHA CELLS.
• A FACTOR/RECEPTOR CELLS OF Alpha cells.
• Fusion of cells/mating
• Surface signals/cellular response
• Signal Transduction Pathway
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Figure 11.1 Communication between mating yeast cells
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Figure 11.2 Communication among bacteria
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Figure 11.2x Myxobacteria
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TYPE OF CELL COMMUNICATION
• Local regulator/growth factors and animal nervous system/ neurotransmitters.
• Distant regulators/hormones such as insulin/have target organs.
• Direct contact/junctions or plasmodesmata between cells.
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Figure 11.3 Local and long-distance cell communication in animals
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Figure 11.4 Communication by direct contact between cells
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TYPE OF CELL COMMUNICATION
• Local regulator/growth factors and animal nervous system/ neurotransmitters.
• Distant regulators/hormones such as insulin/have target organs.
• Direct contact/junctions or plasmodesmata between cells.
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SIGNAL RECEPTION
• Signal molecule binds to receptor protein, causing the protein to change shape.
• Signal receptors are plasma-protein membranes.
• G protein linked receptor.
• Ligand binding activities.
• Lipid hormones, nitric oxide.
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Figure 11.5 Overview of cell signaling (Layer 1)
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Figure 11.5 Overview of cell signaling (Layer 2)
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Figure 11.5 Overview of cell signaling (Layer 3)
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Figure 11.6 The structure of a G-protein-linked receptor
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SIGNAL TRANSDUCTION PATHWAYS• PATHWAYS RELAY SIGNALS FROM
RECEPTORS TO CELLULAR PROCESSES.
• PROTEIN PHOSPHORYLATION, ADD PHOSPHATE GROUPS.
• SECONDARY MESSANGERS, SMALL IONS & MOLECULES.
• CYCLIC AMP AND Ca++ ion.
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Figure 11.7 The functioning of a G-protein-linked receptor
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Figure 11.8 The structure and function of a tyrosine-kinase receptor
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Figure 11.9 A ligand-gated ion-channel receptor
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CELLULAR RESPONSES TO SIGNALS• IN RESPONSE TO SIGNAL, CELL MAY
REGULATE ACTIVTIES IN THE CYTOPLASM OR TRANSCRIPTION IN THE NUCLEUS.
• ELABORATE PATHWAYS AMPLIFY AND SPECIFY THE CELLS RESPONSE TO SIGNALS.