Challenges to the Modern Synthesis Stephen Jay Gould, 1941-2002Nils Eldredge, 1941-2002.

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Challenges to the Modern Synthesis Stephen Jay Gould, 1941-2002 Nils Eldredge, 1941-2002
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Transcript of Challenges to the Modern Synthesis Stephen Jay Gould, 1941-2002Nils Eldredge, 1941-2002.

Page 1: Challenges to the Modern Synthesis Stephen Jay Gould, 1941-2002Nils Eldredge, 1941-2002.

Challenges to the Modern Synthesis

Stephen Jay Gould, 1941-2002 Nils Eldredge, 1941-2002

Page 2: Challenges to the Modern Synthesis Stephen Jay Gould, 1941-2002Nils Eldredge, 1941-2002.

DNA

Page 3: Challenges to the Modern Synthesis Stephen Jay Gould, 1941-2002Nils Eldredge, 1941-2002.

Transcription

Page 4: Challenges to the Modern Synthesis Stephen Jay Gould, 1941-2002Nils Eldredge, 1941-2002.

Translation

Notion of “gene expression”

Page 5: Challenges to the Modern Synthesis Stephen Jay Gould, 1941-2002Nils Eldredge, 1941-2002.

Question: Why aren’t “identical twins” identical?

Page 6: Challenges to the Modern Synthesis Stephen Jay Gould, 1941-2002Nils Eldredge, 1941-2002.

Epigenetics

From Wikipedia:

“Epigenetics is the study of heritable changes in gene expression or cellular phenotype caused by mechanisms other than changes in the underlying DNA sequence.”

http://www.pbs.org/wgbh/nova/body/epigenetics.html

Is epigenetics why cloned animals don’t fare well?

Page 7: Challenges to the Modern Synthesis Stephen Jay Gould, 1941-2002Nils Eldredge, 1941-2002.

Genetic regulation

Page 8: Challenges to the Modern Synthesis Stephen Jay Gould, 1941-2002Nils Eldredge, 1941-2002.

Genetic Switches (in “non-expressed” regions)

Page 9: Challenges to the Modern Synthesis Stephen Jay Gould, 1941-2002Nils Eldredge, 1941-2002.

Genetic Regulatory Networks

Page 10: Challenges to the Modern Synthesis Stephen Jay Gould, 1941-2002Nils Eldredge, 1941-2002.

Random Boolean Networksas models of genetic regulatory networks