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AN ISO 9001:2000 COMPANY

THE INDUSTRY LEADER

in LABORATORY SOLUTIONS

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CENTRONEMS

ComplianceMeet today’s toughest standards with total support documentation –designed to meet FDA, GLP, GMP, AABB, AAALAC, JCAHO, USDA and other regulatory requirements.

ProtectionSafeguard valuable research, effort and product.

Cost ControlReduce losses and limit your exposure to risk.

Time PreservationSave energy and resources with streamlined, automated data collection.

Integrated Access ControlTotal security for individual rooms, corridors or entire facility.

Centralized Alarm SystemsFrom local sonic to voice telephoned to e-mail alarm capabilities, day and night.

Centralized Data CollectionReducing the costs and time associated with chart or manual recordings while increasing accuracy.

ValidationOn-site software validation and on-site IQ/OQ, including calibration, probe verification and user training.Premium calibration services available.

NetworkingOperates over existing TCP/IP LAN/WAN infrastructure. Multi-user, multi-building, multi-site capability.

Report GenerationUser-defined reports based on time, date or activity. Customizable reports with Crystal Reports.

Alarm and data collection has never looked so good, so

straightforward and so information-rich. Rees Scientific’s Centron

Environmental Monitoring Systems (EMS) answer the monitoring

and access challenges faced in blood banks, research

laboratories, lab animal research facilities and other high-security

facilities the world over.

A single Centron system can monitor a diverse facility with multiple

locations while it provides instant data access and sophisticated

analysis right from your desktop computer.

Our continually expanding line of monitors is matched only by our

around-the-clock service and support team. Always expandable,

divisible and network compatible, Rees systems provide you with

alarm notification, programming flexibility, rich documentation

and a host of other features. Rees systems are used by virtually

every major pharmaceutical company worldwide and the Centron

has become the industry’s standard in blood banks and similar

facilities.

Our full turnkey installation goes well beyond hardware and

software. Rees provides complete installation including IQ/OQ,

system validation, sensor calibration and thorough training of your

personnel, as well as service and warranties on all parts and labor.

The Ultimate Research Engine

Refrigerators

Freezers and Ultra-low

Freezers

Cold Rooms

Stability Chambers

LN2 Tanks

Incubators

Animal Holding Rooms

Clean Rooms

Centron EMS systems are easily and

economically expandable. Each central processing

station, or node, monitors up to 128 inputs, whether

hardwired, wireless, or a combination of both. Each

node also controls up to 64 digital outputs. Up to

100 nodes can be networked together to form a

single system. Hardwired Multiplex-Remote Input

(MPX) panels monitor up to 16 sensors each. Each

output panel controls up to 8 outputs.

This modular design provides you the flexibility of

purchasing all of the solutions together at the time of

construction/renovation, or starting with a solution

that meets your current needs and budget, and

expanding as needed.

With any type of input, from any number of users, through

any configuration of buildings, you can view and print

validated reports from any touch screen or terminal with

appropriate security clearance.

With easy-to-use Windows® based software that offers

real-time readings and extensive user-friendly features

and benefits, Rees Scientific’s Centron systems take

environmental monitoring and access control to the next

level in performance and innovation.

Windows® based Centron software is available in English, Spanish and German.

WHAT DO WE MONITOR?

Every moment of every day- we’re watching.

A desktop version of the Centron, the Centron Tower is a small, self-contained

unit designed to fit on your desktop or lab bench and accessed using a

standard monitor, keyboard and mouse. Perfect for facilities where the wall-

mounted enclosure and touch-screen are not practical.

The Satellite Tower allows monitoring of up to eight inputs and is invaluable

when you have to oversee multiple locations with only a few monitor points at

each site. Operating over your existing TCP/IP WAN, the Satellite Tower has all

of the capabilities of the Centron system. The Satellite Tower can operate

independently or as an additional node on an existing Centron EMS.

Rees Scientific’s WebServer allows users to stay in touch with their critical

equipment from virtually anywhere. Authorized users can access your facility in

real time from any web browser. Full alarm handling, input programming

capabilities and reports are available. The WebServer combines the

convenience of our WebServer software with the security of a validated file

server needed for GMP/GLP and other regulated facilities and eliminates the

need to install the Centron software on each network terminal.

e-Centron combines several exceptional Rees Scientific features into one

convenient and economical package. e-Centron unites Centron hardware,

Web Access, an internal CDRW drive, Autobackup software, and 4 hour

battery backup; all delivered in a Tower Chassis, complete with printer,

monitor, keyboard and mouse. An unlimited number of authorized users can

access the system through a standard web browser.

The latest evolution of Centron EMS, CentronSQL provides a more robust

database engine operating on Oracle or SQL providing advanced and custom

reports utilizing Crystal Reports. Additional enhancements include extended 21

CFR 11 security, independent logging rates for each input, scalable maps, and

graphical input status reports. WebServer software option is available to

provide access to users from virtually anywhere.

Our wireless sensors will do for monitoring what wireless

phones have done for communication - give you the

freedom to move about. Ideal for facilities that routinely

move or relocate equipment, these sensors allow you to

monitor equipment that you previously could not. Great

for research animal holding rooms and clean rooms where

conduit is required as well as temporary or rented facilities

where you are not permitted to run data lines. We can

provide you with quick and clean installations.

How does it work?

There are three basic components to the system: transmitter,

repeater (transceiver) and receiver. Each unit being

monitored has a battery powered transmitter and a sensor.

Typical temperature applications such as refrigerators and

freezers are monitored using a standard thermistor probe.

Each transmitter is identified by its serial number and

operates at 418 MHz*. For those far-reaching sensors we

offer a repeater designed to relay the signal to the receiver.

The 900 MHz* Wireless Receiver connects to your Centron

node and employs Digital Spread Spectrum (DSS)

technology to eliminate the risk of interference with other

devices of the same frequency. For economical monitoring

of remote locations, we offer a device that can monitor up

to 96 points and is capable of buffering data in case

communication to the system is disrupted. (*433MHz and

2.4GHz for European installations)

Does the entire system have to be wireless?

No. Add wireless sensors to existing hard wired Centron EMS

systems or go completely wireless. For some applications,

hard wiring a sensor may make more sense. Our wireless

system is designed to work with all of our existing Centron

systems. Our solution allows you to have the best of both

worlds. Either way, you will enjoy all of the advanced network

features, superior alarm dial out capabilities, and secure data

that you have come to know and trust from Rees Scientific.

Centron’s alarm capabilities are smart and smooth.

With local sonic, voice telephoned and e-mail alarm

notification, Centron nodes notify the right person at

home or office, cellular phone, pager or e-mail,

anytime.

With Centron’s generous telephone alarm

capabilities, (up to 200 contacts per Centron node

organized into 20 to 100 call lists with day and night

differentiation), facilities have the convenience of

departmentalizing and de-centralizing alarm

notification. In other words, delegate alarm handling

to the personnel best qualified to handle the

problem. Set up the system to decide who gets

notified, and how. Free system administrators from

routine calls, but allow them to retain control,

accountability, and supervisory authority. Share the

system with multiple departments, and allow each to

handle its own alarms, generate its own reports, and

use its own SOPs.

Centron’s voice mail quality alarm notification reports

current condition readings and high and low alarm

parameters, allowing you to respond by telephone

with precision and speed. The Centron also offers

custom voice tags to specifically name each input in

the alarm messages.

Alarmed and Ready. Independent, Valid

Set Alarm Notification and Logging Rates for each input.

Monitor all of your equipment and facilities

Always within Reach

Optional cellular backup monitors the primary

telephone line. If the telephone line fails or becomes

disconnected, Centron EMS will automatically alert

users of the failure and assume all dial-out duties until

the line is restored.

Alarm notification in the event a node or remote panel goes offline.

Because Centron operates over your organization’s

existing TCP/IP LAN/WAN infrastructure, access is

unlimited. You also have the option to access the

system over the Internet from any computer in the

world, making it easy to monitor and control multiple

sites on your schedule.

Multi-user Networking

and Endless Divisibility

Departmental segregation by input allows divisibility

that makes the most sense for today’s multi-

departmental facilities. Restrict user access based on

an individual’s position, department and/or

qualifications. Allow users to only view their own

inputs on facility floor plans, reports, graphs, etc.

ated, Networked or Web based -

We have a configuration to meet your needs.

System Integrity

and Data Protection

Centron has a comprehensive system to protect your

valuable data and prevent system failures. It has built-

in battery backup, watchdog timer auto-reset, a dead-

system alarm, and it automatically backs up its own

data. Each data record is recorded first to its own hard

drive and then immediately thereafter to the network

drive. If network communication is lost or the network

drive goes down, the data will still be stored on the

Centron’s internal drive and immediately update the

network drive when communication is re-established.

The Centron’s internal hard drive allows for a nearly

infinite amount of data buffering and essentially

eliminates any possibility of data loss.

Autobackup software backs up data to a network

location, local drive, or CD/CDRW. Performing

backups in “Shared” mode allows the system to

continue to update while the backup is being

performed. An integrated CDRW drive is available

with Centron systems to make the process convenient,

secure and easy to use.

with one system - whether across the building, across town or across the country!

CENTRONSQL Software - Security, Ease of Use, Integrity, Sharing, Quality -----

These are just a few of the data challenges facing Researchand Manufacturing today.

In addition to rock solid stability, industry standard data

formats, superior multi-user operation and a

dramatically improved system overview, CentronSQL

provides a vast new array of analysis reports that can

be easily accessed from any workstation. Reports can

be generated based on time, date, activity, input, event

type or multiple criteria allowing you access to what

you need to know, when you need to know it.

Our most recent software advance, CentronSQL,

provides the ultimate in High Security Monitoring.

CentronSQL allows the use of either Oracle or

Microsoft’s SQL Server as the database engine for the

system. Centron Nodes are equipped with Microsoft’s

MSDE 2000 data engine, which is suitable for use as

the main data engine for small systems. Critical GxP

audit trails and system program data are kept in

encrypted files.

Advanced and Custom Report Generation

Capable of sophisticated graphs

Simultaneously show detail boxes for multiple inputs on scalable floor plans with easily identifiable icons.

The next generation of reporting

In addition to monitoring your critical equipment and

processes, the system monitors itself. BuddyWatch

reports if a node goes off-line. While each node is

independent and can log data and alarm without

connectivity to the database engine, DatabaseWatch

will dial out to report that the node is no longer

CentronSQL also offers new software alarm features. Email notification now alerts users with more detail including

the input number, name, current reading, low limit and high limit. Additionally, the number of users that can be on the

system simultaneously has increased from 10 to 50!

connecting to the database engine. MPX Comm and

Battery Alarms warn if a MPX subpanel goes off-line.

These additional alarms allow for voice telephone

notification or e-mails to be made and all standard

alarming functions to occur.

Documented excellence...Whether a routine readings history or alarm history,

every Centron report gives a detailed, easy-to-

understand, accurate account that users find

invaluable on many levels. All information, from all

nodes in your system, is permanently logged to the

Readings or Event History Files and is encrypted to

ensure data integrity. You can now fully document how

alarms are handled, produce complete audit trails

and print information-rich event history reports, on

demand.

21 CFR 11 and Validation settings

Running Log provides documentation of allevents, alarm conditions, programming andcalibration changes for all selected nodes.

Real-time readings are simply a click away.Name, number, status, current reading, andlow and high limits are instantly available.

Color-coded icons display real time changesin a probe’s status.

Alarm Instruction Forms that you createappear in the alarm control panel ensuring theproper handling of any alarm situation.

Alarm handling from real-time display ofprobes allows you the option of enteringcomments or notes regarding the event.

Event Reports allow you to view alarm,programming and other events with acomplete GMP compliant audit trail. View orprint these reports selected by date and inputname, number, or event types. A fewexamples of event types include alarmmessages, alarm disable, alarm reset, errormessages and program changes. You canalso print notes or comments that have beenentered regarding specific events.

Graphs of readings and daily highs, lows,and averages are available at the touch of abutton. Touch graphed points on-screen andsee complete and accurate details.

Reports of readings, highs, lows, averages,and even mean kinetic temperatures areeasily produced for individual inputs, allinputs, or individual departments. Automaticdaily printouts are an option for all reportsand graphs.

Program Change Audit Trail documentswhat a given condition was before, what itwas changed to, who made the change,when and why.

21 CFR 11 (Electronic Signatures)encrypted files, dual element signing of useractions, intruder account lockout withadministrator notification, password lengthcontrol and expiration, comment expectedfor user actions, even online review andapproval of records with electronicsignatures. We’ve got it all.

Detailed graphs of events Detailed event history

... the ingredients for compliance success.

Ensure regulatory compliance by adding electronic comments to events and tracking the status of investigations.

Validation Our systems are designed with validation in mind. Rees Scientific combines over 20 years of experience in

both Environmental Hardware design and Validation Protocol development to offer comprehensive packages for all

of its Environmental Monitoring and Access Control Systems.

Validated site or not, the fact that Rees Scientific’s Centron systems include hardware and

software validation with every installation adds value for you. Our field engineers follow

an on-site IQ/OQ qualification test protocol that proves that your system operates as

designed on your site. We validate all of our software before release and provide you with

a complete test report proving effective performance of all system functions. What this

means to you - essentially bug-free software that you can trust, and notification of any

problems that may be discovered. Clients are welcome to review our protocols before

purchase, and are welcome to audit our site.

Installation

Highly skilled, factory-trained installation specialists

install, program and test your new equipment.

IQ/OQ Testing

On-site technicians perform our validation protocol,

calibrate sensors, and provide you with documented

proof of reliable system function.

Software Validation

Software validation report includes test results and

documentation to satisfy any inspector.

Training

On installation, our experts train your personnel in

Centron’s use, and provide documented proof of their

knowledge.

On-Site Service

Our nationwide network of factory employed, factory

trained service engineers ensure that your system is

well maintained, up-to-date, and working properly -

always. Our 24/7 technical support team answers your

questions, and our service dispatch fixes problems for

you with unparalleled speed. What will YOU do when the

auditor is at YOUR door?

Val/Serv A• Biannual On-site IQ/OQ Validation• Current Software Validation manual• Software updates to current version• Calibration of all temperature and humidity sensors

with a NIST traceable device• On-site training at the time of the validation• 24-hour telephone technical support

• On-site service includes parts and labor

Val/Serv B• Annual On-site IQ/OQ Validation• Current Software Validation manual• Software updates to current version• Calibration of all temperature and humidity sensors

with a NIST traceable device• On-site training at the time of the validation• 24-hour telephone technical support• On-site service includes parts and labor

Val Second• Six-month On-site IQ/OQ Validation• Current Software Validation manual• Current IQ/OQ Validation Protocol manual• Software updates to current version• Calibration of all temperature and humidity sensors

with a NIST traceable device• On-site training at the time of the validation• 24-hour telephone technical support

• On-site service includes parts and labor

Service Contract• 24-hour telephone technical support• On-site service includes parts and labor

Premium Calibration Services

• Five Point Certified Sensors with Certificate (RTD Sensors and High Accuracy Humidity Sensors) –

In the past, many of our customers have had a need to certify the accuracy of the sensor over the entire range, not

just at a single point. Rees Scientific now offers high accuracy RTD and humidity sensors that will be calibrated at

5 different points. In addition to the certificate of calibration, Rees Scientific will also execute a 5-point loop

calibration on all inputs using certified sensors.

• Three Point Calibration (available for those choosing to stay with traditional thermistor probes) –

The Three Point Calibration tests each input at three separate points along the range of it’s operation providing

added assurance that the probes will give accurate readings during high and low alarm conditions, as well as their

normal operating set points.

• Alarm Limit Testing – More commonly referred to as “Fire and Ice” testing, the Alarm Limit Testing protocol

is designed to prove that the system will indeed alarm at each sensors set high and low alarm parameters.

• Premium Sensor Calibration Protocols are also available.

is always part of the package.

Validation and Service Packages

A powerful validated card access system with the ease

and convenience of a Windows® based software

application, the Rees Scientific Access Control system

enables you to control and monitor access to your entire

facility from your desktop computer.

Expandable to grow as your needs grow, the Rees

Scientific Access Control system can handle up to 32,000

cards, 300 access groups, 128 reader groups, 16 alarm

zones, and 32 elevator control groups. Up to 64

schedules/time zones and 32 holiday exceptions control

auto lock/unlock, automatic security alarm activation/

deactivation, and door access control. Eight levels of

pass code security ensure that only the proper individuals

are afforded the appropriate access.

Eliminating the need for separate alarm control panels,

the Rees Scientific Access Control System integrates all

door switches, window bugs and motion sensors, which

can be activated or deactivated by a simple swipe of the

access card. Interfacing with Rees Scientific’s EMS

provides complete control of your security and

environment.

CCTV integration and a photo database allows you to

compare the stored photo with the view from the CCTV

camera to “See Who Enters”, ensuring that access cards

are being used only by the authorized cardholder.

Quickly locate an individual in your large, multi-site

facility by using the “Find a Cardholder” feature to

instantly locate the last card reader accessed.

A variety of user-defined reports based on time, date,

and activity, including attendance can be viewed on-

screen or printed out. They can even be set to print out

automatically.

Additional features include:

• Anti-passback settings prevent individuals from

sharing card access

• Real time on-screen simultaneous display of input

status on all selected nodes

• Interlocking doors for clean rooms

• Graphical floor plans/maps

• Multi-user platform runs over existing TCP/IP network

• Monitoring of analog inputs

• CentronSQL software available

Turn your Centron into a Security Guard.

Feel confident and protected 24/7.

1007 Whitehead Road ExtensionTrenton, NJ 08638

1 800 327.3141 or 609 530.1055 International +31 (0) 48 757 0487

sales@reesscientific.comwww.reesscientific.com

Providing the highest quality environmental

monitoring, access control and automated

watering solutions that deliver unparalleled

documentation, notification, validation and

loss prevention for the research community

and beyond.

PRNT2075.0601Copyright 2006 Rees Scientific Corporation All rights reserved.