CENTRO MEDICO GAZCUE

liNTERNATliONAL liNSTliTUTE

OF MEDICAL SCIENCE

HOSPITAL AND CLINICS (THE RAPHAH GROUP, LTD)

Immuno-Oncology Department/ Diagn6sticos Inmuno-Oncol6gico

CENTRO MEDICO GAZCUE

liNTERNATliONAL liN§TliTUTE

OF MEDICAL SCIENCE

HOSPITAL AND CLliNliC§ Immuno-Oncology Department I Diagn6sticos Inmuno -Onc ol6gico

Alzheimer's

Arthritis

Cancer

Cardiovascular Disease

Diabetes

MS Immune Disease

HIV/AIDS

Av. Bolivar# 357 Santo Domingo, Dominican Republic

Tels.: (809) 685-6198 • 685-3807 Fax: (809) 685-3354

KNTERNATKONAL

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Dear Interested One:

International Institute of Med ical Science Hospit al and Clinics (IIMS /HC) maint ains one of the fine st medi ca l treatment facilities in the world. Our program is not co nsidered an island treatment facility. We are a full service hospital with the most modern full service fac iliti es in the world.

IIHS /HC also maintains agg ressive resea rch progra ms dealing with all aspect s of Chronic Degenera tive Disease (COD). Currently, resea rch emph as is is in the area of cancer, HIV /AIDS , M.S. , cardiova scular disease , seve re allergie s, arthriti s, and viral diseases such as EBY. All pro grams of therapy and treat ment are programs utilized prev iously with pro ven results. If at any time, an experim ental pro gram is utiliz ed , it is done with the full know ledge of the pati ent. Please read the package co mpletly to under stand our program(s).

We trust after co mplete review of our Admission s infor mation packa ge you will be full y inform ed as to our services.

Tru sting for good hea lth and longevity!

The Admini stration

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A WORD FROM THE DIRECTOR

Dr. Gregory E. Caplinger MD, DSc ., FACIP, FIAM

M any ask why are we so successfu l? Do we have cures for ca ncer, AIDS,

or other C. D.D. 's -NO. How eve r, we have found a cure fo r something mor e serious -lack of concern!

Furth er, we have

In todays techno logically advanced medica l system we have somehow forgotten about the basic hum an need s of CARING. Here at IIMS we work dilig ently because we do care . We fee l for each and every sufferi ng pat ient.

discovered a new Bio log ical Medicine and prot oco l; Immu St irn / CA P Immunol ogica l Protoco l, which is effec tively being utili zed in the treat ment of cancer and HIV / AIDS (see the brochures entitl ed Advanced in ... Treat ment , 1998) .

It is therefo re our goa l and conv iction to prov ide the best care poss ible.

We are be liev ing fo r your Hea lth and your need for a mira cle.

Sincere ly,

Dr. Gregory E. Caplinger MD , DSc ., FACIP, FIAM

DIR ECTOR

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Immuno-Oncology Department/ Diagn6sticos Inmuno-Oncol6gico CENTRO MEDICO GAZCUE No. 357 Bolivar. Santo Domingo, Dominican Republic

International Institute of Medical Science Hospital and Clinics

(IIMS/HC) is a division of the parent Company, THE RAPHAH GROUP,

LTD, which is a well known organization serving Latin America and the

Caribbean in the area of health care and medicine. Further, the facility is not

an offshore clinic for foreign patients. It is and was created for Dominicans

with an emphasis on "Chronic Degenerative Disease"(CDD) .

PROGRESSIVE THERAPY FOR CHRON1C DEGENERATIVE DISEASE

International Institute of Medical Science Hospital and Clinics of Santo

Domingo is one of the most progressive and innovative facilities in the

world. International Institute of Medical Science integrates successful and

proven therapies from around the world in an individualized manner to

effectively treat the patient as a person. International Institute of Medical

Science has incorporated into the philosophy of the institution the thought ,

"WHERE THERE IS LIFE , THERE IS HOPE!".

International Institute of Medical Science is an affiliate of and a entity within

"CENTRO MEDICO GAZCUE" and therefore has acce ss to progressive

research, 24 hour on call physicians and all of the ancillary services ...

All out-patients are housed at variou s hotel s sitting on the Caribbean with

every amenity available . Patients are cared for either as ambulatory

(outpatients) or admitted to the hospital depending on the need (s) of each .

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I\'TER~.AT :tO: VA L ]~ST IT'L;~r·E OF ) lED]C'/\L SC:IE.'\'C'E HOSPITAL AN ][) CIL,H'\':IC0

STATE OF THE ART DIAGNOSTICS

General Radiology

Laborato,y Services

I nternational Institute of Medical Science firmly believes that every patient program begins with a complete evaluation as to the, "eliology" (cause) of their disease. Therefore. the clinic maintains state of the art facilities:

- Complete Laboratory - SMAC/CBC - Immunology laborator y - Tumor Market Si11dies for Cancer - Endocrinology Evaluation ( Hormones) - Phase contrast Microscopy (Medical Microscopy)

innovative method for screening for 59 different disease entities and monitoring a patient 's progress daily. Futhe1; Dark Field Microscopy is utilized regularly.

- Complete Non-Invasive Vascular laboratory -D-1/R Computerized Scanner for complete 3-D scans of the entire human body.

PROGRESSIVE THERAPIES

After a patient is completely evaluated. they are placed on an individualized program to address their specific needs. All programs are directed by our staff physicians.

Therapy, as stared, is an individualized approach with the utilization of the major four approved therapies (cancer) being: ( 1) Surgery, (2) Chemotherapy (low dose/ fractionated dose), (3) Radiation (low dose), and (4) Immunotherapy.

Protocols following ASCO (American Society of Clinical Oncology) are observed with modification(s).

Further, in conjunction with new data from NCI (National Cancer Institute / USA) and the international comunity, it is realized that proper diet and emotional factors (stress, anxiety, etc. ) play vital roles in patients. Therefore, these factors are addressed with each patient.

The general emphasis therapeutically for most "CDD's" in the Oncology Department is that of lmmunotherapy. Since the late 70's the founders have been utilizing what is now a proven successful group of "Biological Medicines" and a protocol known as: lmmuStirir" I CAP Immu nological Protoco l. This medicine and protocol have proven to be very successful and with little or no adverse effects.

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U "TER~AT IO~AL I\'ST:IT'l:TE OF YlEDICr\ L SClENCE H DSP'IT.i\ L AND CL IN :ICo

The various protocols and medicines used, to name a few, are:

P - C Immunotherapy Protocol (lmmuStinl'1/CAP Immunological Protocol) one of the more success ful cancer immunotherapies utilizing proven immunological medications.

ImmuStinf ·!. a successfu l non-toxic "Biological Medicine" prepared specifically for the needs of the patient. Used in cancer, HIV / AIDS, M. S. EBY. arthritis and most if not all Chronic Degenerative Diseases which normally have as a causal factor an Immunological deficiency.

Amino Acid Hyperalimentation - I.Y. amino acid therapy

Progressive Pharmacology - The clepai1ment/clinic maintains an advanced pharmacy and their own pharmaceutical company. Products used include: (New products/Biologicals are in development.) lmmu Stim Tabs - a proven immunological medication which stimulates T cells, B cells and NK cells. Fractionated Dose Chemotherapy - a low dose approach to cancer chemotherapy.

Interferon - immunotherapy for some cancers Interleukin - one of the most effective immunological drugs utilized for cancer, HIV/ AIDS. Hepat itis C, etc.

Other treatment methods include whole body hyperthermia, multiple wave oscillation (MWO) therapy, Radio Lazer therapy (medium range lazer for tumors), Radiation therapy (low dose - Linear accelerator) surgery as needed and nutritional adjunctive therapy. These are only a few of the many unique products and services utilized.

FACILITY

International Institute of Med ical Science Hospital and Clinics is unique in that the .. ambience" or atmosphere is one of comfort and quality with a sense of home. Therefore, the patient feels more relaxed without the sense of being in a hospital.

International Institute of Medical Science maintains an ultra modern facility with ICU, modern surgical suite. outpatient IV therapy suite andl00+ private rooms with space for a companion to sleep.

Futher the Hospital / Clinic is constantly expanding and building to better serve the needs of patients.

Med ical Micros copy Administration

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.11\l'l'ER:2\fATJO:\'AL .l:"~TJTC'TE OF ~'1ED:I C.r\ !L :SCIE~CE 'HOSP IT.-\l. A.YD l'L IN :ICS

AFFILIATE(S)

International Institute of Medical Science Hospital and Clinics maintains strong relations with some or the "top" medical facilities, hospitals and doctors throughout the world. To name a few they include:

I. CIMEQ - the leader in scientific/ medical developments in Latin America. (located in Havana Cuba)

2. Sussex General Hospital / Sussex Medical Centre - a leader in the area of immunology in Europe (England - UK/ consultation facility - group).

3. Internat ional Institutes of Health - which is an International Institute patterned after the NIH of the USA. The primary function of the IIH is to gather, evalute and disseminate medical information related to CDD 's and new innovative treatments.

Further, the department/c linic is continually building relationships with physicians and cl inical facilities worldwide to better treat the patient.

INTERNATIONAL STAFF Di : Ramon Feliz, Chief of Oncological Surgery

Each patient is assigned a team of physicians, nurses, therapists and periphera l health care professionals from "literally" every discipline as needed. The Department has a staff of nationally and internat ionally known physicians.

The department is under the directio n of a leading pioneer in immuno-onco logy holding both clinical (M,.D.) and research (D.Sc.) degrees in medicine.

Patient in Treatment

7

All of the treating physicians are licensed to practice medicine in the Dominican Republic and hold Board Certifications in the Dom inican Republ ic, USA or Europe. They also serve key positions in various medical schools and are active in research in CD D's.

The staff utilizes the team approach with each patient. Prior to the start of intens ive therapy, a team of physicians carefu lly rev iews the diagnostic data and formulates the best approach to therapy to rece ive for maximum results.

FEES

il 1TE,:R::'\.i\T ilON.-\L :l 1ST:l1r'l.;'TE OF }115:D:tCA L SC:UE:1 'C E Fl OSP:11L-\L A~D CL:lNllCS

No rmal treatm ent ma y be either in hospita l or out patient. Plea se note the followin g fees: (apro ximat e and may change without not ice) . Futh er, a depos it of U. S. ( va riabl e and to be deter mined according to history and progno sis) is requ ired pr ior to arriva l (this depends upon pre-arr iva l rev iew of reco rds and medica l history ). The fees wi ll be subtra cted from the depos it. In the eve nt a ref und is du e, it is issued upon dischar ge .

Each pat ient need s to plan an initi al visit of up to thi rty days (plu s).

** GENERAL SCHEDU LE (Ca nce r - HIV /A IDS )

VISIT / CYCLE DURATION (DAYS) TIME BETWEEN (DAYS)

# 1 21- 30 30

# 2 5 - 14 30

# 3 5 - 10 30

# 4 5 -7 60

# 5 7 90

#6 7 120

# 7 MAINTENANCE THERAPY

** The noted schedule is based upon an average pati ent. Furt her, the pro gra m(s) at the Institute are conside rably less expe nsive than other ava ilable programs. At tim es the Inst itutes fees are 70 % less . All fees noted are for the standard ambulat ory pro gram .

AL L PRICES ARE SUBJECT TO CHANGE WITHO UT NOTICE!

FINANCES An initi a l deposit of (VAR IABL E) is due prio r to arri ving at the fac ility.

Thi s is done via bank wire.

Therea fter, each Frida y the responsible party will be prese nted a bill of the bala nce to be paid in full with ce 1tified US funds. Personal check(s) canno t and will not be acce pted. At tim es the facility is ab le to accep t cred it card paym ents .

The fees includ e the entir e progra m exce pt med ications (for take hom e) and additio nal analys is if needed , which are a ll very reaso nab le . Howeve r, the prim ary Immu Stim med ica tions are inc luded as indicated in the fina ncia l le tter.

INSURANCE We do not accep t insurance direct ly in most cases. However, a ll rece ipts are coded with the acce pted US /Europea n codes for re imbur sement. Ma ny compan ies do reimburse However , we wo rk in conjunc tion with an Int ernatio nally recog nized insurance c learing hou se and our ow n insurance depa1tment which recove rs up to 90 % of cla ims. Further , they may be able to pre­approve yo ur trea tment.

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lNTER:\f A.Tl[ 01\'.,\l , I\fST IT'lJTE OF ~\1:E:D:I CAL SC:IK "'CE !l~IOSP:n ~I\I., AND CLIIN lC'S

STAFF Each patient is evaluated by a team of physicians headed by our internationally renowned oncologist/immunologist Dr. Caplinger.

Once again, the hospital maintains a complete staff of physicians covering all specialties from the Dominican Republic and throughout the world.

DISCHARGE Each patient is discharged with a complete program consisting of:

I. Diet 2. Medication(s) 3. Special Treatment(s) 4. Exercise 5. Follow-up Directions

As stated, many times we coordinate with your local physician and other doctors in your area. Further, as stated, we are not an offshore treatment facility. Patients choose our facility from other countries because we have proven treatment programs that combine approved therapies from around, the world.

Further, we are now in the process of setting up a network of worldwide physicians for patient follow up and treatment.

ADMISSIONS

Admissions may be arranged by your physician or yourself. For admission arrangements and information (fees, programs, insurance info, etc.) please contact us at: (Physicians inquires welcomed)

INTERNATIONAL INSTITUTE OF MEDICAL SCIENCE HOSPITAL AND CLINICS C/O Centro Medico Gazcue Ave. Bolivar No. 357 Santo Domingo, Dominican Republic (809) 685 - 6198 / (809) 685-3354

ADMISSIONS PROCEDURE One must first undergo an interview with one of the intake doctors or counselors. This involves the following: (depending upon the illness). Further, fill out completely the enclosed form and fax.

( ) I. Contact made via telephone. ( ) 2. Fax all pertinent records, i.e.

( ) A. Recent bloodwork ( ) B. X-Ray, CT, MRI reports ( ) C. Biopsy reports ( ) D. History/Physical examinations ( ) E. Treatment records, to include current medications ( ) F. Diagnosis

( 3. Fill out information sheet and fax (included here in) ( ) 4. Pre-Admjssion Exam with consulting doctor where indicated. ( ) 5. Final interview with administrator ( ) 6. Appointment elate

After all arrangements are made - all travel. etc. is coordinated through ourAdmin istration and North American office of Patient Affairs.

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:11 ''TER.~ .. ~:r1o~AL L\TSTITl"TE OF 2'1ED1Ci\L scrn::\TCE HOSPrrAL .A 1:D CL ]NilCS

ACCREDITATION / REGISTRATION

Centro Medico Gazcue, S. A. is a fully approved private clinjc and hospital from both the Dominican goverment and the well respected British West Indies Health Confederat ion.

REFERENCE(S) / TESTIMONIAL(S)

In maintaining a high professional standard, the department has on file patient testimonials. While these in and of themselves do not attest to the credibility, they do indeed attest to our genera l approach to health care. However, these are not routinely published.

Further, we do maintain a current list of persons willing to freely discuss International Institute of Medical Science with interested persons. (upon request)

In conclusion, we at Internationa l Institute of Medical Science Hospital and Clinics want to be of service to you in any way possible. Please feel encouraged to contact us if we can be of further asistance. However, due to the enormous volume of telephone calls and inquiries your request will be addressed ASAP but telephone calls will be returned collect and you must make a telephone appointment.

May your Health Be Prosperous,

THE STAFF

* COMPARATIVE FEES (USD)

TREATMENT YEAR YEAR LIFETIME 1 5 (YEARLY)

up TO $15,000 CHEMOTHERAPY $35 0 , 000

RADIOTHERAPY DEPENDS ON SITE AND FREQUENCY!

ALTERNATIVE $90,000 ??? $ 10,000 THERAPY PLUS

* The data was taken from information printed and distributed by the National Cancer Jnstirute (NCI). American Cancer Society (ACS) and various hospitals in the USA and Europe. Data on Alternative Therapies was gotten via inquiries to alternative physicians, clinics and the office for alternative Medicine at the National Institutes of Health (NIH) U.S.A. This data is believed to be co1Tect as of December 1997.

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:INTE:RN/\TI ON 1\L I '.'.-nTTT'J"I •: OF Y\K[)] CX L SCJ '.~:J\T E 'HD0PIT 1\L i\~D CLL\'.IC'o

PRE ADMISSION INFORMATION ( Fax to (809) 685-3354)

I.Name _ __ _ Age _ _ _ Sex __ _ _

Add ress

Home Tel.: ( Fax Tel.: ( )

Type of Employment _ _ _ _ _

Tel.: ( Fax Tel. : (

II. MEDICAL INFORMATION

A. Diagnos is ____ _ Ca ncer / Type

Location ___ _ ____ _ 0 HIV /AIDS

0 M.S. D Arth riti s D Lupus 0 EBY D Diabe tes

D Oth er _ __ _ _

B. Symptoms: (L ist the top 4)

I.---- - -- - ---

2. ------- - -- -

3. ---------- -

4. - - -- - - - - ---

C. Energy Leve l (on a Sca le of l -10 with 10 being goo d norm al energy) ______ _

D. Date o f Diagno sis _ _ ____ _

E. Describe all treatment you have done to date (include surge ,y, chemotherapy, vitamins etc .) :

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F. List all current med icati ons with dose and strength - includ e all natural products:

G. Current Physician: --- - --- - ---

Specialty _____________ _ Tel.: ( ) _________ _

Fax.: ( ) - - - - - - - - -- - --

III.INSURANCE

Company _____________ _ Tel.: ( ) _________ _

Fax.: ( ) ___ _ ________ _ Type of Policy _ _ __ _ _ _ __ _

(include a copy of yo ur insura nce card )

IV. EXPLAIN IN YOUR OWN WORDS HOW YOU FEEL:

V. INCLUDE WITH THIS INFORMATION THE FOLLOWING:

1. Laboratory report( s) - blood work 2. Official diagnosis - path ology report or laborat ory report 3. Most recent CT, MRI other radiology repo rts .

PATIENT SIG. DATE

WHERE THERE IS LIFE THERE IS HOPE!

Av. Bolivar# 357 Santo Domingo, Dominican Republic

Tels.: (809) 685-6198 • 685-3807 Fax: (809) 685-3354

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