Centre for Microscopy, Characterisation and Analysis...Centre for Microscopy, Characterisation and...

Centre for Microscopy, Characterisation and Analysis

CMCA | 2011 – 2012

CRICOS Provider Code: 00126G UniPrint 96944

Centre for Microscopy, Characterisation and AnalysisThe University of Western AustraliaM010, 35 Stirling HighwayCrawley WA 6009Tel: +61 8 6488 2770Fax: +61 8 6488 1087Email: [email protected]

COVER IMAGE / FALSE COLOURED SCANNING

ELECTRON MICROGRAPH OF A TRYPANOSOME

TRYPOMASTIGOTE ON A DYING CELL.

COURTESY: ADRIANA BOTERO AND PETA CLODE.

From the Director p01

Affiliations p02

Techniques p04

Feature Story p06

Research Highlights p07

Biomedical Sciences p08

IMAGE / PROJECT INVOLVED INVESTIGATING DROUGHT

RESISTANCE MECHANISMS OF A NEW PERENNIAL

HERBACEOUS PASTURE LEGUME. 100UM THICK

SECTIONS OF STEM WERE PREPARED ON A VIBRATOME

AND IMAGES TAKEN ON ZEISS AXIOSKOP OPTICAL

MICROSCOPE. IMAGES PETA CLODE, PROJECT: KEVIN

FOSTER.

IMAGE /THIS ELECTRON - MICROSCOPY IMAGE

SHOWS STRUCTURES FORMED BY SELF-ASSEMBLY

OF MAGNETIC IRON-OXIDE NANOPARTICLES. A SMALL

WATER DROPLET CONTAINING OVER A TRILLION NANO-

PARTICLES WAS ALLOWED TO DRY ON FILM. THE HIGH

SURFACE-TENSION OF THE WATER DROPLET DREW

PARTICLES TOGETHER AS IT DRIED, RESULTING IN

THESE LARGE SINGLE-LAYER STRUCTURES. TAKEN BY

RAHI VARSANI, PHD STUDENT AT CMCA.

pressure on our workhorse Zeiss SEM with a new high-performance imaging instrument. Our team, led by CMCA’s Deputy Director Martin Saunders, will exhaustively survey the available offerings – travelling to The Netherlands, Singapore and Japan to view and operate the instruments, testing samples brought from Australia, and finally select the best performing instrument that meets the needs of the UWA and WA research communities.

So why is CMCA so successful? One reason is how CMCA determines what capabilities to acquire. It begins by being plugged in to the research community. As a hub for more than 400 researchers, we have a lot of opportunity to learn what is required, by listening and talking to people, but also by doing. CMCA’s academic and technical staff are continually interacting with users and potential users in myriad ways. From conducting new user meetings, an initial step in our User Pathway, to running training courses, to responding to industry enquiries, we are continuously absorbing feedback on what is required and where we should be going next.

And that’s not all; CMCA’s Technique Group Leaders are an important conduit as well, complemented by Applications Group Leaders, who cut across techniques to bring a whole-of-area perspective on our portfolio of capabilities. And intelligence is gathered through our national linkages, as nodes of the National

IMAGE / CMCA DIRECTOR – WINTHROP

PROFESSOR DAVID SAMPSON.

Imaging Facility and the Australian Microscopy and Microanalysis Research Facility, and through our international academic networks. We learn what is working elsewhere, what is not, and what our friends are planning for next.

The next year will be an exciting time at the CMCA, as we bed down our engagement with the International Atomic Energy Agency, as the first university in their network, and get on with the job of measuring samples, and as we plan for the long-awaited move into purpose-designed integrated facilities in the WAIMR North building on the QEII Campus, and install our state-of-the-art preclinical Bruker 9.4T/310mm micro-MRI.

In this 50th anniversary year, CMCA’s long-standing culture of excellence will come together with renewal of our facilities to ensure we are well placed to offer excellence at world-class levels for the next 50 years – Top 50 by 2050!!

The University of Western Australia | 01

Earth Sciences p12

Physical Sciences p15

Research training, teaching and usage p17

Industry and Impact p18


Centre Highlights p21

Staff p26

Conferences and Visits p30

Journal Papers p33

From the DirectorThe first electron microscope arrived at UWA in 1963. So, the CMCA celebrates its 50th Anniversary in 2013, in the University’s Centenary Year: fifty years of conceptualising, winning funds for, and installing and operating cutting-edge instruments to advance leading-edge research at UWA.

In 2012, we were again very successful in winning funds from the Australian Research Council for new platforms - in transmission electron microscopy, scanning electron microscopy, flow cytometry and atomic force microscopy. Two of our four successes were supported by a strategic alliance of the four publicly funded universities: the transmission electron microscopy bid led by CMCA and the atomic force microscopy bid led by our Curtin University colleagues. The combined value of our successes was $4.46 million, with ARC funding of $2.28 million – making the CMCA one of the most successful infrastructure organisations in the country in winning Australian Research Council infrastructure grants. Since 2008, the CMCA has achieved a 100% success rate on ten such grants.

Our ten-year old flagship transmission electron microscope – the JEOL 3000, will finally be replaced with the latest generation of a capability undergoing continuous evolution, and we will finally relieve the

AffiliationsThe CMCA is a focus for microscopy and microanalysis activities across Western Australia and, through strong links and collaborations, has both a national and international reputation.

Established in 1963 as a science infrastructure facility within The University of Western Australia to support research activity, the Centre has a long and distinguished record of collaboration with researchers, industry and government agencies in the provision of research expertise and technology.

Its world-class facilities, with a replacement cost of $45M, comprise an extensive range of microscopy, microanalysis and imaging instruments across six sites.

Nanoscale Characterisation Centre WA (NCC) and the Western Australian Centre for Microscopy (WACM)On 30 June 2012, the Nanoscale Characterisation Centre WA (NCC), a State Government funded Centre of Excellence for which CMCA was the lead node, completed its funding term. NCC’s focus was on providing infrastructure and expertise to maximise benefits to the Western Australian community from institutional and industry research and development in WA. The primary objective of the NCC was to provide continuity in major equipment acquisitions to ensure that the State’s researchers and industry have access to state-of-the-art technology. During it’s five-year program, NCC significantly exceeded its original targets for instrument acquisitions and the delivery of characterisation training, research support and industry engagement.

The NCC was founded upon a collaborative agreement between the four publicly funded universities in Western Australia, which together form the Western Australian Centre for Microscopy (WACM). The WACM agreement between the partner institutions continues to operate, with CMCA continuing to act as the hub for microscopy activities in the State, and strong cross-institutional support for infrastructure acquisition and management.

Australian Microscopy and Microanalysis Research Facility (AMMRF)Established under the Commonwealth Government’s National Collaborative Research Infrastructure Strategy (NCRIS), AMMRF is Australia’s peak research facility for the characterisation of materials through advanced microscopy and microanalysis. The AMMRF facilitates access for all Australian researchers to world-class equipment, instrumentation and expertise through a national grid of nodes with varying microscopy capabilities and an array of flagship instrument platforms at the international cutting edge.

The CMCA is the West Australian node of the AMMRF and features the flagship ion probe capabilities, which consist of the NanoSIMS50 and IMS 1280. Each of these instruments is unique to the Southern Hemisphere.

The CMCA also collaborates with the John de Laeter Centre, which enjoys linked laboratory status in the AMMRF, in the management and operation of Western Australia’s ion probe facilities.

02 | cmca.uwa.edu.au

IMAGE / CULTURED ALVEOLUS TAKEN ON THE

NIKON FLUORESCENT CONFOCAL MICROSCOPE AT

CMCA TAKEN BY FIONA PIXLEY.

National Imaging Facility (NIF)Established under NCRIS, the Bioimaging Facility focuses on provision of state-of-the-art magnetic resonance, molecular and allied imaging technologies for application to animals, plants and materials for the Australian research community.

A successful 2009 LIEF grant saw the CMCA become the Western Australian node of the facility, the first organisation in the country to host two NCRIS capabilities. The facility features new capabilities for Western Australia: in vivo micro-CT and multispectral imaging, with the instruments commissioned in 2011. To these instruments will be added micro magnetic resonance imaging (micro MRI) to coincide with completion of the new WAIMR building at QEII where the Facility will be housed.

AuScopeAuScope is a characterisation capability funded through the National Collaborative Research Infrastructure Strategy (NCRIS) with a focus on establishing world-class research infrastructure to characterise the structure and evolution of the Australian continent in a global context from surface to core in space and time.

In partnership with the AMMRF, the Government of Western Australia and UWA, AuScope enabled the establishment of the world-class ion microprobe facility at CMCA, for the benefit of all Australian researchers.

Australian National Fabrication Facility (ANFF)Established under NCRIS, the Australian National Fabrication Facility (ANFF) provides researchers and industry with access to state-of-the-art fabrication facilities.

The capability provided by ANFF enables users to process hard materials (metals, composites and ceramics) and soft materials (polymers and polymer-biological moieties) and transform these into structures that have application in sensors, medical devices, nanophotonics and nanoelectronics.

The CMCA houses the Panalytical Empyrean powder diffractometer.



X-ray DiffractionÌÌ Charge density measurement ÌÌ Powder X-ray diffraction ÌÌ Small molecule structure determinationÌÌ Thin film analysis, XRD phase analysis, rocking curve analysis

Scanning Electron MicrosopyÌÌ Secondary and backscattered electron imagingÌÌ Environmental SEMÌÌ X-ray microanalysis

Nuclear Magnetic Resonance SpectroscopyÌÌ Multi dimensional spectra ÌÌ Multinuclear spectraÌÌ Solid state spectra

AMMRF Flagship Ion Probe FacilityÌÌ Nanoscale mass spectrometryÌÌ High-precision isotope ratios

Scanning Probe MicroscopyÌÌ Atomic force microscopyÌÌ Magnetic force microscopyÌÌ Nanoindentation

Transmission Electron MicroscopyÌÌ Analytical spectroscopyÌÌ DiffractionÌÌ Element mappingÌÌ ImagingÌÌ Tomography


NEW Optical-Confocal InstrumentIn 2012 CMCA purchased a new Nikon A1R confocal and multiphoton microscope. This new instrument is being housed in the Large Animal Facility on Crawley Campus.

The system is capable of simultaneous or sequential image collection using galvanometer and resonant scanners and four photomultiplier fluorescence detectors and a DIC transmission detector. The multiphoton components comprise a Coherent Chameleon II pulsed laser (700nm – 1000nm), NDD detectors, and the Nikon Apo 25 x WMP dipping objective. An objective inverter will allow an effective upright configuration for the Nikon Ti E (inverted) microscope which is suitable for in-vivo animal imaging.


Biological Mass Spectrometry ÌÌ Electron and chemical ionisationÌÌ Fast atom bombardment

Bioimaging FacilityÌÌ Multi spectral imagingÌÌ X-ray micro-computed tomography

Specimen PreparationÌÌ Biological sciencesÌÌ Cryogenic preparationÌÌ Physical sciences

Visualisation and SimulationÌÌ Data analysisÌÌ Image processing and reconstruction

Flow CytometryÌÌ Cell sortingÌÌ Population analysis

Optical and Confocal MicroscopyÌÌ Confocal, multiphoton and fluoresence microscopyÌÌ Laser microdissectionÌÌ Live cell imagingÌÌ Automated digital histology


TechniquesThe CMCA provides the capabilities to characterise the continuum from atoms to small animals.


On 23 October 2012 The University of Western Australia became the first university in the world to join the United Nations international nuclear verification program, using UWA’s advanced ion microprobe technology to help monitor global nuclear safeguards. A high-level delegation from the International Atomic Energy Agency (IAEA), including the Deputy Director General of the IAEA, Mr Herman Nackaerts, the Section Head, Department of Safeguards (IAEA) Mr John Patten, and Dr Robert Floyd, Director General, Australian Safeguards & Non-Proliferation Office (ASNO), took part in a signing ceremony at the University. The IAEA maintains a network of analytical labs that monitor samples from areas suspected of undisclosed use of nuclear materials from the nuclear fuel cycle.

The accreditation followed stringent testing and certification of UWA’s IMS 1280 ion microprobe at the University’s world-class Centre for Microscopy, Characterisation and Analysis (CMCA). The IMS 1280 ion probe is a flagship capability of the Australian Microscopy & Microanalysis Research Facility (AMMRF), and supported also by AuScope and the WA Government.

The instrument will be used to analyse micron-sized environmental particles collected by IAEA inspectors

Feature StoryUWA expertise to aid international nuclear inspections

from nuclear facilities around the world to search for evidence of undeclared uranium enrichment activities.

The primary purpose of testing is to police the UN nuclear non-proliferation treaty and monitor nuclear capabilities by testing for signs of potentially illicit uranium enrichment facilities or weapons development programs.

Material collected for analysis at UWA will be dust-sized particles containing minute amounts of uranium – less than in a bottle of spring water – and not classified as nuclear or radioactive material under international convention. The samples require no special shielding and will be screened for radiation by the IAEA before being sent for testing. UWA will not receive any samples considered to be radioactive.

UWA is the first university in the world to gain accreditation to the Agency’s Network of Analytical Laboratories, which consists of members from six countries, the European Union, and the UN.

MR HERMAN NACKAERTS (IAEA) AND PROFESSOR PAUL JOHNSON (UWA VICE-CHANCELLOR).

IMAGE / CAMECA IMS 1280 ION PROBE.


Biomedical sciences p8

Earth sciences p12

Physical sciences p15

Research Highlights

IMAGE: NEUROMUSCULAR JUNCTION FROM

THE FORELIMB (TRICEPS) OF A NEONATAL (P0)

WESTERN GREY KANGAROO, TAKEN ON NIKON A1SI

SPECTRAL DETECTOR CONFOCAL SYSTEM AT QEII.

IMAGE BY IVAN HONG, MURDOCH UNIVERSITY.

Biomedical sciences

The magnetic sense Understanding how animals navigate over both short and long distances is central to defining the behaviour and ecology of species and underpins our ability to test cognition, memory and communication.

Pigeons are famous for their navigational abilities, relying on a range of stimuli to find their way home, often in conditions with minimal visual information. For many years, researchers have demonstrated that these birds, and many other animal species, are able to utilise the Earth’s magnetic field as a navigational aid, but exactly how this is achieved remains one of the great unsolved mysteries in biology.

A report from a German research group in 2003, that rapidly became dogma, suggested that iron-containing cells found in the upper beaks of pigeons were the proposed magnetoreceptors. However, an international team lead by Australian Dr David Keays at the Institute of Molecular Pathology in Vienna showed conclusively that this is not the case. Dr Jeremy Shaw and Prof. Martin Saunders from the CMCA assisted with the study, using a range of analytical TEM methods to re-examine these cells, and concluded that the iron minerals present were inconsistent with that needed for magnetoreception and were in fact common macrophages (a type of immune cell).

The new study, published in the journal Nature, reset thinking in the field of magnetoreception and calls for the revision of a significant body of research based on the original findings from 2003. While the pigeon’s ability to magnetorecept remains valid, the exact anatomical location and neurological basis of the sense remains an open question.

C.D. Treiber, M.C. Salzer, J. Riegler, N.Edelman, C.Sugar, M. Breuss, P. Pichler, H. Cadiou, M. Saunders, M. Lythgoe, J. Shaw, D.A. Keays, “Clusters of iron-rich cells in the upper beak of pigeons are macrophages not magnetosensitive neurons”, Nature 484 (7394) 367-370, 2012


Stem cells in breast milk

The mammary gland is a very unique organ in the human body, and of great interest in stem cell research, because it is one of few that can undergo repeated cycles of development and regression in a mature adult. When a woman becomes pregnant, the simple network of ducts that makes up the non-lactating mammary gland start to branch and elongate, and form milk-secreting ‘alveoli’ at their ends. The result is an organ that, when stimulated by infant suckling, can produce all the components required to nourish a growing baby on demand – pretty amazing! After breastfeeding is stopped, the body clears the lactating cells and the gland returns to its simple network of ducts.

Researchers at the School of Biomedical, Biomolecular and Chemical Sciences and the Centre for Microscopy, Characterisation and Analysis at The University of Western Australia have shown that this dramatic change in size and architecture of the gland is fuelled by proliferation of epithelial stem

cells within the gland that evolve into different functional types of cells. The different cells that arise work together to communicate signals from the outside of the gland, like the bloodstream or nervous system, to control milk production and ejection.

Researchers grew the milk-secreting structures from stem cells harvested from expressed breast milk. It is thought that these stem cells are exfoliated from the alveoli and ducts by the stretching and contraction forces as milk fills and empties from the gland. They showed that when a single one of these stem cells is grown in specialized soft agar they form alveoli that look almost identical to the milk-producing alveoli in a breast feeding woman.

The Image shown here is of a single cultured alveolus taken on the Nikon fluorescent confocal microscope at CMCA@QEII. This particular image is a cross section through the middle of a whole alveolus, showing a perimeter of stem cells (red) surrounding a forming layer of milk-secreting functional cells (green).

Flow cytometry also performed at CMCA@QEII was used to detect cell surface marker expression and characterize changes in the cell phenotype over time in culture.

Analyzing the structures this way has helped elucidate the process of alveolus formation and to investigate the factors that drive their development from a single stem cell. This work is published in the peer-reviewed journal Stem Cells, on which CMCA’s Tracey Lee-Pullen and Assoc Prof Paul Rigby are co-authors.

E. Thomas, T. Lee-Pullen, P. Rigby, P. Hartman, J. Xu, N. Reps: “Receptor activator of NF-Κb Ligand promotes proliferation of a putative mammary stem cell unique to the lactating epithelium”, Stem Cells, 11 (6), 1255-1264, 2012.

IMAGE / SINGLE CULTURED ALVEOLUS TAKEN ON THE

NIKON FLUORESCENT CONFOCAL MICROSCOPE AT

CMCA AT QEII.


Understanding how cancer spreadsMost cancer deaths are caused by spread of the primary tumour to other parts of the body in a process known as metastasis. Therapeutic strategies which could limit metastasis represent an exciting potential approach to preventing cancer associated morbidity and mortality.

One of the mechanisms by which tumour cells can become mobile and metastasize is by subverting the ability of the host immune macrophages to invade tissue. In response to a cancer growth, macrophages will invade the tumour

and attempt to destroy it. However, tumour cells express a molecule called colony stimulating factor-1 (CSF-1), which binds to a receptor (CSF-1R) on the macrophage surface. Once this receptor is bound, the host macrophages undergo specific changes in motility and phenotype to become Tumour Associated Macrophages (TAMs). TAMs assist tumour spread by secreting epidermal growth factor (EGF) which helps the tumour and TAF move to a nearby blood vessels where they can spread through the blood stream, seeding cancers elsewhere in the host. Without the macrophage, the ability of the cancer to spread would be greatly reduced.

Associate Professor Fiona Pixley and collaborators from the School of Pharmacology and the Centre for Microscopy, Characterisation and Analysis at The University of Western Australia combined broad range of cytometry techniques at CMCA, including time lapse, confocal and TIRF immunofluorescence, transmission and scanning electron microscopy, to characterise the specific changes in morphology and motility of CSF-1 stimulated macrophages.

By using specifically targeted point mutations, the researchers were able to pinpoint specific signalling events which lead to this characteristic morphology as invading macrophages proliferate and become TAFs. By specifically switching off these signalling events, the researchers were able to both prevent TAM motility and limit tumour cell invasion.

This breakthrough research has both contributed to the fundamental understanding of immune cell signalling and motility, as well as uncovering potential new therapeutic targets in the treatment and prevention of metastatic cancer.

These highly important breakthroughs have been published in the Journal of Biological Chemistry and Cell Science 124, 2021-2031, 2011.

THE CELL IS A GROWTH FACTOR STIMULATED

MACROPHAGE SHOWN SPREADING ON A

FIBRONECTIN COATED COVERSLIP. IMAGE

DEMONSTRATES NON-MUSCLE MYOSIN

CONTRACTION (GREEN - PMLC) ASSOCIATED WITH

THE F-ACTIN CYTOSKELETON (RED). NUCLEAR

STAINING IS DAPI.

A BONE MARROW-DERIVED MACROPHAGE SEEDED

ON ALEXA568-LABELLED FIBRONECTIN AND

GELATIN, FIXED AND STAINED FOR F-ACTIN WITH

ALEXA488 PHALLOIDIN. THE IMAGE SHOWS THE

MACROPHAGE DEGRADING THE UNDERLYING

EXTRACELLULAR MATRIX THROUGH FORMATION

OF PODOSOMAL ROSETTES.


The work used the CMCA’s NMR facility in the Bayliss building managed by Associate Professor Lindsay Byrne, to confirm the structures of the synthetic intermediates and drug candidates, and featured on the ABC’s 7:30 WA on 25th May 2012.

Johnston, T.H., Millar, Z., Huot, P., Wagg, K., Thiele, S., Salomonczyk, D., Yong-Kee, C.J., Gandy, M.N., McIldowie, M., Lewis, K.D., Gomez-Ramirez, J., Lee, J., Fox, S.H., Martin-Iverson, M., Nash, J.E., Piggott, M.J., Brotchie, J.M., A novel MDMA analogue, UWA-101, that lacks psychoactivity and cytotoxicity, enhances L-DOPA benefit in parkinsonian primates, FASEB Journal, 26, 2154-2163, 2012

Associate Professor Matthew Piggott’s research group, in the School of Chemistry and Biochemistry, has synthesized a number of MDMA analogues (new compounds with a similar chemical structure to MDMA) with the aim of retaining the beneficial effects of MDMA, but removing its undesirable attributes. The work has been carried out in conjunction with Parkinson’s disease experts in Toronto, and the group of psychopharmacologist Professor Mathew Martin-Iverson at UWA. The most promising analogue, UWA-101, is even more effective than MDMA at enhancing the quality of levodopa therapy. In the best animal model of Parkinson’s disease, UWA-101 lengthened the therapeutic duration by up to 30%. More importantly, UWA-101 increased the proportion of on-time that was of good quality (i.e. without disabling dyskinesia) by 178%. If translated to a medicine, this would mean that Parkinson’s patients could take their medication less frequently and get a better quality result from it.

Seeking to improve quality of life for parkinson’s sufferersParkinson’s patients have a great deal of difficulty moving without medication. The drug levodopa restores their movement, but with prolonged use side-effects often develop. These include a reduction in therapeutic duration (‘on-time’) and jerky, involuntary movements known as dyskinesia. Dyskinesia is often confused as a symptom of Parkinson’s disease, when in fact it is a side-effect of the treatment. It has been known for some time that the drug most commonly known as ‘ecstasy’, methylenedioxymethamphetamine (MDMA), ameliorates the side-effects of levodopa therapy. MDMA has no therapeutic potential because it makes users ‘high’ and there is also evidence that MDMA may be neurotoxic, or at least responsible for long-term, deleterious changes in brain chemistry.

ASSOCIATE PROFESSOR PIGGOTT DISCUSSES POSSIBLE MODIFICATIONS TO THE MDMA SCAFFOLD WITH PHD CANDIDATE MICHAEL GANDY

(A MEMBER OF HIS RESEARCH GROUP).


Earth sciences

A discovery at The University of Western Australia may aid Curiosity Rover on MarsThe discovery that microbes helped shape rare spheres of iron-oxide on Earth may aid the recent Curiosity rover in its search for signs of extra - terrestrial life in similar rocks on Mars.

Spherical iron-oxide concretions – dubbed “blueberries”, due to their size and shape – were first found on the red planet in 2004 by an earlier NASA robotic probe – Opportunity – providing some of the first evidence for liquid water on Mars. Earth-based analogues for these “blueberries” are found in the Jurassic Navajo Sandstone near the Colorado River, Utah, where the concretions range in size from small marbles to cannonballs and consist of a hard shell of iron oxide surrounding a softer sandy interior.

Dr David Wacey and Assoc. Professor Matt Kilburn, in collaboration with scientists from the University of Nebraska, used the Cameca NanoSIMS 50 to show a clear relationship between microbe-like forms and concentrations of biological elements such as carbon and nitrogen in the terrestrial iron-oxide concretions. Their findings feature on the front cover of the August 2012 issue of the journal Geology.

Previous theories suggested these concretions were formed by simple, non-biological chemical reactions. However, the new data show clear evidence that microbes were essential in their formation. This raises the possibility that Martian “blueberries” may not only reveal that water was present on Mars – but also life too.

Throughout time, microbes have adapted to survive in some unlikely, and potentially hostile, environments, scavenging nutrients and deriving energy from the meagre sources available. These microbes used Siderite, an iron carbonate mineral, as an energy and carbon source. Over geological time scales, most biological signatures (e.g., DNA or organic biomarker molecules) are lost, but the presence of biological elements and the carbon isotope signature should be preserved, assuming that no extraneous forces were at work to remove or alter them (e.g., geological metamorphism, or weathering). If the surface of Mars has been largely inactive for the past 4 billion years, then the ‘blueberries’ may represent the intact fossilised remains of microbial activity.

K. A. Weber, T. L. Spanbauer, D. Wacey, M. Kilburn, D.B. Loope, R.M. Kettler “Biosignatures link microorganisms to iron mineralization in a paleoaquifer” Geology, 40 (8) 747-750, 2012

IMAGE RIGHT PAGE (L-R) / PLANE-POLARISED

LIGHT IMAGE OF FRERE GRANULAR IRON

FORMATION.

GLOBAL DEPOSITION OF IRON FORMATIONS TO

MANTLE SUPERPLUME VOLCANISM.

PLANE POLARISED LIGHT IMAGE OF EUHEDRAL

ZIRCON CRYSTAL IN CHLORITISED TUFF.


A new study published in the journal Nature in April, 2012, provides a possible explanation for the puzzling reappearance of major iron formations long after the rise in atmospheric oxygen about 2.4 billion years ago, which should have ended their deposition.

Iron formations are unique sedimentary rocks with no modern analogue. Most iron formations were deposited in the oceans before free oxygen first accumulated in Earth’s atmosphere about 2.4 billion years ago (the so-called Great Oxidation Event), and are characterized by interlayering of iron and silica-rich bands. However, after a gap of about 500 million years, major iron formations re-emerged, although the younger iron formations are mostly composed of iron-rich granules and silica. The re-occurrence of major iron formations has been an enduring enigma because the buildup of oxygen in the atmosphere and hydrosphere after the Great Oxidation Event should have prevented iron formations from developing.

Major iron formations about 1.9-1.8 billion years old are found in both North America and Australia. The North American deposits have been accurately dated to 1.88 billion years, however, the Australian iron formations, the Frere Formation in the Earaheedy Basin, were thought to be significantly younger, i.e., about 1.84 billion years. Therefore, it was uncertain whether the younger, post-oxidation iron formations provided information about the composition of the global ocean or conditions in restricted or closed basins.

Researchers from Curtin University, the University of Manitoba, CMCA at The University of Western Australia and the Geological Survey of Western Australia, led by Prof. Birger Rasmussen, discovered cm-thick beds of volcanic ash in drill cores from the Frere Formation. They were able to date zircon crystals in the ash beds, using the Sensitive High-Resolution Ion Micro Probes (SHRIMPs) at Curtin University, to show that the Frere Formation was deposited at the same time as the iron formations in North America. Therefore, the deposition of iron formations on two different continents was synchronous 1.9 billion years ago and probably reflects the composition of the global ocean.

The deposition of iron formations requires seawater that is rich in dissolved iron but contains little or no oxygen below the surface water layer. (This is why iron formations are not deposited from modern oxygenated seawater.) The deposition of major iron formations at about 1.9 billion years ago shows a remarkable correlation in time with a short-lived but intense interval of global basaltic igneous activity, a possible mantle superplume event. The researchers propose that extensive, plume-related basaltic magmatism on land and in the ocean basins released vast volumes of iron into the global ocean, overwhelming the supply of oxygen and promoting the deposition of iron formations across the world. If correct, this means that processes deep within the Earth radically changed the chemistry of the global ocean, although the atmosphere was not affected.

The equally dramatic disappearance of iron formations some 40 million years later can be explained as a consequence of rapidly waning igneous activity that allowed the ocean to become dominated by seawater oxidants once more, such that iron formations could no longer be deposited. These findings not only explain the sudden appearance and disappearance of major iron formations about 1.9 billion years ago, but also provide an explanation for the preservation of an oxygen-rich atmosphere above an oxygen-poor ocean at this time.

The interactions between deep Earth processes and the surface environment leave subtle clues in the chemistry of sedimentary and volcanic rocks. Precise geochronology is the key to deciphering these clues and understanding the relationships between the chemistry of the hydrosphere and atmosphere, and the deep Earth, which can provide insights into significant changes in the evolution of the Earth.

This study was funded by the Australian Research Council and the West Australian Government through the Exploration Incentive (Royalties for Regions) scheme.

B. Rasmussen, I.R. Fletcher, A. Bekker, J.R. Muhling, C. J. Gregory, A.M. Thorne. Published as a Letter, Nature, 484, 498-501 April 26, 2012

What a difference a date makes: global deposition of iron formations in response to mantle superplume volcanism


Mobilization of Ti, Zr and Th in a laterite profile, Jarrahdale, Western AustraliaThe elements titanium, zirconium and thorium are commonly considered to be immobile in most geological environments. Because of their supposed immobility, they are used as references to evaluate the movement of other elements in studies of chemical fluxes in Earth materials. However, their mobility during weathering is not well understood, and therefore it is important to understand more about their behaviour in surface settings so that element mobility in soil profiles, for example, can be evaluated. To this end, PhD student Xin Du, under the supervision of Assoc. Prof. Andrew Rate and Dr Mary Gee from the School of Earth and Environment at The University of Western Australia, has completed a study of the mode of occurrence and mobility of Ti, Zr and Th in a laterite profile developed over granite at Jarrahdale, Western Australia. (Laterite is a residuum of intense surface weathering of primary rocks. Characteristically red in colour, it is composed of secondary oxides of iron and aluminium, as well as quartz and kaolinite.)

The mobility of Ti, Zr and Th has been assessed at both the mineral and profile scales and the mode of occurrence has been investigated through the combined use of geochemical data from bulk samples, and in-situ data determined by scanning electron microscopy (SEM), electron probe microanalysis (EPMA) at CMCA, and synchrotron X-ray powder diffraction (SXRD).

In the parent rock, Ti is located in titanite (CaTiSiO5) and ilmenite (FeTiO3), Zr is predominantly hosted by zircon (ZrSiO4) and thorite

(ThSiO4), the main host for Th, also contains ~10% Zr. In addition to the main hosts, a range of other accessory minerals contain minor to trace amounts of Ti, Zr and Th.

In the laterite, titanite is not seen and Ti is located in ilmenite and the TiO2 polymorphs rutile and anatase. Zircon remains the main host of Zr, but Zr was also found in a poorly crystalline phase associated with Ce forming a rim and coating around Al-Fe matrix in pores in the laterite. Thorite is altered in the laterite, and released Th is precipitated in secondary Rare Earth Element phosphates such as florencite and rhabdophane. In addition, up to 5% Th was incorporated in neoformed, poorly crystalline phases in the laterite, demonstrating the mobilization and redistribution of Th on the sample scale.

Xin is now at the School of Environmental Studies, China University of Geosciences. Her study shows that the stability of the primary minerals during weathering is the main control on the mobility and redistribution of Ti, Zr and Th. It demonstrates that Ti, Zr and Th are mobile on a variety of scales in the laterite profile, and this needs to be considered when evaluating the fluxes of other elements during intense weathering. Outcomes from this research have been published in Chemical Geology*.

X. Du, A.W. Rate, M.A.M. Gee. “Redistribution and mobilization of titanium, zirconium and thorium in an intensely weathered lateritic profile in Western Australia”, Chemical Geology, 330-331, 101-115, 2012

IMAGE / X-RAY ELEMENT MAPS FROM THE CMCA

MICROPROBE SHOWING THE DISTRIBUTION OF

ZR, AL, CE AND FE IN NEWLY FORMED, POORLY

CRYSTALLINE MINERALS IN LATERITE.


Physical sciences

The world thinnest materialGraphene is a wonder material that promises to transform the future. Graphene is made of carbon atoms arranged in a honeycomb structure. It is the world’s thinnest, strongest and most conductive material, and promises a range of diverse applications; from smartphones and ultrafast broadband to drug delivery and computer chips.

Two Russian-émigré scientists at the University of Manchester who won their joint Nobel prize in physics for graphene discovery in 2010, used sticky Scotch tape to peel off one atom thick layer of graphene from graphite block. Currently, the synthesis of large-scale graphene involves either epitaxial deposition

on silicon carbide or deposition on nickel with followed chemical exfoliation (separation) of graphene. This exfoliation necessity triggered chemical researchers to find more efficient/practical ways to produce graphene sheets.

UWA Prof. Raston’s research team is focusing on chemical engineering and has developed a method for graphene sheets separation that reduced chances of defects formation and chemical degradation in graphene. Their investigations using transmission electron microscope (TEM) at CMCA revealed the size, shape and crystal structure of the separated graphene sheets produced by the new method. The work has been published in high-impact journal

Chemical Communications of Royal Society of Chemistry.

Xianjue Chen et al. Chem. Commun. 48, 3703–3705, 2012

How to build an artificial nose Micro-Electro-Mechanical Systems, or MEMS, is a technology that can be defined as miniaturised electro-mechanical devices and structures that are made using microfabrication. The physical dimensions of MEMS chips can vary from well below one micron all the way to several millimeters. The types of MEMS devices can vary from relatively simple structures having no moving elements, to extremely complex electromechanical systems with multiple moving elements under the control of integrated microelectronics. MEMS technology is enabling new discoveries in many sciences such as biotechnology, medicine, and communications.

The PhD research project of Gino Putrino from the School of Electrical, Electronic and Computer Engineering, is aimed at helping to build biological and chemical sensors. The project is focused on micro-electro-mechanical (MEMS) sensors that can detect spoiled fruit, explosives in your suitcase, or even lung cancer. In his two-minute cartoon which can be seen

IMAGE / TEM IMAGES OF FULLY SEPARATED AND PARTIALLY SEPARATED GRAPHENE SHEETS WITH CORRESPONDING DIFFRACTION PATTERN AND AFM IMAGE OF GRAPHENE.


Tissue engineering for bones repairsTissue/organ repair has been the ultimate goal of surgery from ancient times to the present. A revolutionary shift is taking place in medicine from using synthetic implants to a tissue engineering approach that uses degradable porous material scaffolds integrated with biological cells or molecules to regenerate tissues. This new approach requires scaffolds that balance mechanical function with cell transport to aid biological delivery and tissue regeneration.

Professor Xiaozhi Hu from the School of Mechanical Engineering at UWA is exploring possible material systems for tissue engineering, driven by potential applications such as orthopedic and dental applications. This research requires the capability to grow coatings with a targeted structure and determine the structure of the coatings in the scanning electron microscope. The research

on YouTube PhD TV Gino called the MEMS sensor “artificial nose”. Gino was one of 12 winners of a world-wide competition for researchers to reduce their work to simple visual ideas that can be understood by everybody.

Plasma enhanced chemical vapour deposition (PECVD) silicon nitride was used as the structural material to fabricate MEMS chips for ‘artificial nose’. The structural integrity of the MEMS components determines primary functionality of the sensor. The power of scanning electron microscopy in these studies is twofold. Firstly, SEM can examine the complex structure and visualise the functional components of “artificial nose” device. Secondly, it can measure local composition at high resolution. The work was published in the Photonics Technology Letters Journal.

Putrino et al.,IEEE Photonics Technology Letters, 24 (24) 2243-2246, 2012

has found that bending strengths of the micro-porous hydroxyapatite-based coatings could match those of surrounding natural bones. Potentially, the composite can be used for bone replacement implants. The work has been published in Journal of American Ceramic Society.

R Sultana et al., Journal of American Ceramic Society, 95 (4). 1212–1215, 2012

IMAGE / SEM IMAGES OF SURFACE MORPHOLOGIES OF HYDROXYAPATITE-BASED COATINGS BEFORE (A) AND (B) AFTER THE

BIOLOGICAL CELLS GROWTH.

(A) (B)


Research training, teaching and usageThe CMCA expanded its training programme in 2012 to reflect the incorporation of the facilities in CMCA@Bayliss and the addition of the ANFF-funded XRD in CMCA@Physics. Attendance of the Centre’s training courses remained steady compared to 2011 numbers at 328 participants. The number of participants in advanced electron microscopy workshops was 48.

Demand for CMCA facilities continued to grow with a ~10% increase in usage for the main facilities at CMCA@Physics and CMCA@QEII. The first full year of reporting of usage at the newly-incorporated CMCA@Bayliss site resulted in almost twenty seven thousand hours being recorded. This brought the total usage figure for 2012 to more than fifty four thousand hours.

EELS Electron Energy-Loss Spectroscopy 15

EFTEM Energy-filtered TEM 13

HRTEM High resolution TEM 9

SAD Selected area diffraction 11

1 to 1 One-on-one teaching MS Mass Spectrometry

CONF/OPT Confocal/Optical Microscopy SEM Scanning Electron Microscopy

EDS Energy-Dispersive X-ray Spectroscopy TEM Transmission Electron Microscopy

FLOW Flow Cytometry XRD X-ray Diffraction

NMR Nuclear Magnetic Ressonace BIF Bioimaging Facility

2011 trainingTotal1 TO 1 111

CONF/OPT 60

EDS 40

FLOW 53

SEM 55

TEM 51

2012 training Total1 TO 1 76

CONF/OPT 52

EDS 46

FLOW 52

MS 6

SEM 86

TEM 37

XRD 49

2011 instrument usage in hours: 33,907 2012 instrument usage in hours: 54,484

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Industry and ImpactCMCA has a long history of partnering with industry from small scale analysis, instrument hire and training of individuals, to large scale consulting and complex research contracts worth hundreds of thousands of dollars.

Access is tailored to the needs of your organisation or project and we welcome queries on how we can apply our expertise and world class instrumentation to your problem solving initiatives.

Woodside Energy– applied research for improved sub-sea engineering designWoodside Energy is one company looking at ways in which they can better inform the current design approach to sub-sea electrical connectors, which are crucial components to offshore operations.

Work at the CMCA was critical to understanding the potential of problems such as biofilm build-up in these harsh environments. The outcomes of this research has better informed the direction of the design team in terms of how to engineer the build of future components.

The CMCA was suited to this type of applied research due to the ability of the Centre to utilise its academic research expertise and compare results across a number of imaging techniques, including SEM and Optical/ Confocal. An additional bonus was the ability to call on expert research knowledge from within The University of Western Australia which gave unique insights into the ideas under scrutiny.

Energy and MineralsÌÌ Alcoa World AluminaÌÌ ALS AmmtecÌÌ Atlas IronÌÌ AusQuestÌÌ BHP BillitonÌÌ Crossland ResourcesÌÌ CSIRO Earth Science & Resource

EngineeringÌÌ Fortescue Metals GroupÌÌ Geological Survey of WAÌÌ Geological Survey NTÌÌ Goldfields Mine ManagementÌÌ Manhattan CorporationÌÌ Oilfield Production TechnologiesÌÌ Paladin ResourcesÌÌ PterodiaÌÌ Thundelarra ExplorationÌÌ United States Geological Service

Environmental and EngineeringÌÌ Analytical Reference LaboratoriesÌÌ Botanic Gardens and Parks

AuthorityÌÌ Department of Agriculture

and FoodÌÌ Envirolab ServicesÌÌ Matrix Composites and

EngineeringÌÌ Orbital EngineeringÌÌ PIHAÌÌ Site Environmental and

Remediation ServicesÌÌ SLR Consulting AustraliaÌÌ TSW AnalyticalÌÌ Woodside Energy ÌÌ Biomedical and MiscellaneousÌÌ AntariaÌÌ Fertility Specialists of WAÌÌ National Measurement InstituteÌÌ PhylogicaÌÌ PivetÌÌ Proteomics International ÌÌ Western Australian Museum

InternationalÌÌ International Atomic Energy

Agency (IAEA)


Grants success

p20

Research Highlights

IMAGE / CULTURED ALVEOLUS TAKEN ON THE NIKON

FLUORESCENT CONFOCAL MICROSCPE

AT CMCA TAKEN BY FIONA PIXLEY.


Grants successARC LIEFThe CMCA has been particularly successful in 2012, receiving $2.68m of funding through four ARC LIEF grant applications. In addition to the four grants, Jeremy Shaw was awarded a DECRA and Peta Clode received a Discovery grant. This was a great result for the CMCA as well as for the individuals concerned.

We acknowledge the leadership of Kathy Heel, Martin Saunders and Peta Clode in preparing the CMCA applications. Curtin University’s Mark Ogden and Marius Martyniuk from School of Electrical, Electronic and Computer Engineering at The University of Western Australia also deserve a mention for their valuable input into the successful outcome for the Atomic Force Microscope suite.

A fifth ARC LIEF success was achieved with Matt Kilburn and Brendan Griffin as CI’s on the Curtin Aztec EBSD bid, led by Steve Reddy.

NHMRC Project GrantPaul Rigby from CMCA will be working with Dr Anthony Kicic and Professors Stephen Stick and Daryl Knight, looking at ‘Defective cell migration as a mechanism of dysregulated asthmatic airway repair’. The team was successful in obtaining a NHMRC Project grant of $595,430.

CMCA researchers David Wacey, Matt Kilburn, John Cliff and Martin Saunders were co-authors of a Nature Geoscience paper published in August 2011. The paper entitled ‘Microfossils of sulfur-metabolizing cells in 3.4 billion-year-old rocks of Western Australia’ described the discovery of Earth’s oldest convincing microfossils. It was picked up by much of the world’s media with around 10,000 articles covering the story in the first few weeks after publication. This has been followed up with inclusion in several new textbooks and popular science books in 2012, including ‘The Wonders of

Top press picksFollowing on from CMCA’s 2010 report, the Royal Society of Biological Sciences paper on the preservation of ancient DNA in fossil eggshells has come up trumps as one of the top 10 downloaded articles for the journal from 2010.

C.L. Oskam, J. Haile, E. McLay, P. Rigby, M.E. Allentoft, M.E. Olsen, C. Bengtsson, G.H. Miller, J-L. Schwenninger, C. Jacomb, R. Walter, A. Baynes, J. Dortch, M. Parker-Pearson, M. Thomas P. Gilbert, R.N. Holdaway, E. Willerslev and M. Bunce , Fossil avian eggshell preserves ancient DNA, Proceedings of the Royal Society of Biological Sciences 1471-2954, March 2010.

Life’ accompanying a major BBC TV series. It was also selected as the August highlight for the 12 most important science & nature events of 2011 by the BBC, alongside events such as the Japan tsunami and the first glimpse of the Higgs-boson www.bbc.co.uk/news/science-environment-15531040.


Staff p26

Centre Highlights

IMAGE / MOUSE HIPPOCAMPUS TAKEN BY ELEANOR

DRUMMOND ON LEICA MPCC CMCA.


CMCA ReviewAs part of the University’s regular cyclical review process, the Centre for Microscopy, Characterisation and Analysis underwent a rigorous review process culminating in a three-day series of interviews conducted by the Review Panel in October 2012.

The panellists provided much positive feedback during the review. The final recommendations are due as we go to press.

Lotterywest “Wake”In the late 1990s, The Centre for Microscopy, Characterisation and Analysis (CMCA) received a substantial grant from Lotterywest. The funds were used to purchase state-of-the-art microscopes to enable researchers to carry out

medical research on cells, the building blocks of the human body. On 8 August 2012, CMCA held a function to retire those instruments, and celebrate the fantastic results achieved by researchers over the years. Lotterywest CEO Jan Stewart and Board Members Andrea Hall and Gary Trinder attended to find out first hand just what had been achieved.

Professor David Sampson, Director of the CMCA, introduced researchers Nathan Pavlos and Ruth Thornton, who spoke about their work. Dr Ruth Thornton used the confocal microscope to investigate middle-ear infections (otitis media). This major health problem in Indigenous communities can lead to permanent hearing loss. Indigenous Australian children account for the highest

prevalence of chronic suppurative otitis media in the world (70 per cent in some remote communities). Dr Thornton’s ongoing research in devising a strategy to make antibiotics effective is set to save almost $3 million every year in lowered treatment costs. This will lead to healthier Australians – particularly Aboriginal children.

On a completely different subject, but no less important in the scientific world, a team led by Murdoch University’s Dr Michael Bunce and including UWA’s Associate Professor Paul Rigby was able to extract enough DNA from 19,000-year old fossilised eggshells to help unravel the puzzle of evolution and link genetic information to changes in the environments in which birds live. Their work even raises the possibility of one day bringing extinct species back to life!

These and many other exciting and important research projects (leading to numerous scientific articles published by Western Australian researchers over the last few years) would not have been possible without Lotterywest’s original grant. Beyond attracting and supporting some of the world’s best scientists and medical researchers, the grant has enabled the CMCA to support researchers right across the scientific frontier on everything from climate change, to coral reefs and the hydrogen economy.

IMAGE / FOSSIL AVIAN EGGSHELL STAINED FOR DNA TAKEN BY PAUL RIGBY, USING THE BIO-RAD MRC.


Why did scientists from Nebraska choose to work with UWA? Karrie A. Weber, Assistant Professor in the School of Biological Sciences, Department of Earth and Atmospheric Sciences at the University of Nebraska, spent quite a bit of time in choosing a facility in which to work.

Her decision to come to The University of Western Australia was made based on the CMCA’s Dave Wacey and his demonstrated experience and success using NanoSIMS to identify microbial fossils.

In Karrie’s experience, working with living or preserved living specimens associated with a mineral matrix is different from working with a fossil. “The basic tools may be similar but I envisioned that there would be other challenges that would likely present”, said Karrie. “I thought NanoSIMS would be a great tool to apply to our research”.

This was Karrie’s first step into the paleo world and she knew she had a learning curve ahead of her. Thus, she decided to contact a facility with demonstrated success in identifying microbial fossils. After much searching, Karrie selected the CMCA at The University of Western Australia as the facility and collaborators that she would most likely identify with.

The collaboration was certainly a success and Karrie was thankful to everyone for their contribution and assistance.

Images of DistinctionAssociate Professor Paul Rigby was awarded an “Image of Distinction” in the Nikon Small World 2012 competition. His image was placed in the top 100 places in the competition. Small World is regarded as the leading forum for showcasing the beauty and complexity of life as seen through the light microscope. The Photomicrography Competition is open to anyone with an interest in microscopy and photography.

Best Materials Science ImageAn award in an AMMRF-sponsored micrograph competition, with over 100 submissions, was won by Chee Ling Tong, a student at UWA. Chee Ling's materials science image, taken at CMCA, for a transmission electron micrograph of a micro-mesoporous silica composite won her the award, which was presented to her by Professor David Sampson at the joint Australian Conference on Microscopy and Microanalysis (ACMM22), Asia-Pacific Microscopy Conference (APMC10) and 2012 International Conference on Nanoscience and Nantechnology (ICONN2012) in February 2012.

IMAGE / CAPEWEED (ARCTOTHECA CALENDULA) –

FLOWER STAMEN AND POLLEN.

IMAGE / TRANSMISSION ELECTRON MICROGRAPH OF A MICRO-MESOPOROUS SILICA COMPOSITE. TAKEN BY

CHEE LING TONG.


Associate Professor Andy Johnson puts his image on a stamp - CystallographyAssociate Professor Andrew Johnson from the CMCA was honoured to have one of his images, a false-colour convergent beam electron diffraction pattern from strontium titanate (SrTiO3) near the 001 Zone Axis, selected to be used in a commemorative stamp issue to celebrate 100 Years of X-Ray Crystallography.

November 2012 marks the centenary of the founding of X-ray crystallography by Lawrence Bragg, a field in which he and his father, William Henry Bragg, made pre-eminent contributions that were recognised by the award of the Nobel Prize for Physics in 1915.

IMAGE / FALSE-COLOUR CONVERGENT BEAM

ELECTRON DIFFRACTION PATTERN FROM STRONTIUM

TITANATE (SRTIO3) NEAR THE 001 ZONE AXIS.


On tour with Incredible Inner SpaceVenture into the micro world of human anatomy and animals with teeth reinforced with iron, scales that reflect light and velvet ‘fingers’ on their skin captured by scientists from the Australian Microscopy and Microanalysis Research Facility.

After its successful three-month display at Questacon, where over 92,000 people saw it, the touring exhibition ‘Incredible Inner Space’ was then viewed by more than 40,000 visitors at Scitech in Perth between January and August 2012. Ms Alison Fowler, Scitech’s Science Programs Coordinator, organised several Meet the Scientist events with CMCA staff.

Hands-on activities allowed scientists to engage Western Australians with cutting-edge science relevant to their lives. The CMCA’s Dr Jeremy Shaw and Assistant Professor Lecia Khor spent time on the Meet the Scientist desk answering queries from the public.

Part of the ‘Incredible Inner Space’ exhibition is also shown online at the ABC Science website.

PhD student Adriana Botero wins best poster awardPhD student Adriana Botero, who is based at Murdoch University, won best poster in the ‘Understanding disease’ category at the 2012 Murdoch Poster Day and received $250. Adriana is supervised by the CMCA’s Associate Professor Peta Clode.

Lights, Camera, Action!Movie making came to CMCA in December when CMCA was chosen to appear in the University’s Centenary advertisement, aired on TV in early 2013. Members of the CMCA’s ion probe facility were filmed in the lab working on the CAMECA IMS 1280 ion probe.

DR JEREMY SHAW AND ASSISTANT PROFESSOR LECIA KHOR MANNING THE STAND AT MEET THE SCIENTIST.


Associate Professor Matthew LindenMatthew started with CMCA in September 2012, returning to UWA where his

research career began with a PhD in Pathology in 2003. He comes from RMIT University in Melbourne where he served as an academic in the School of Medical Sciences. Matthew founded and led the RMIT University flow cytometry core facility, which grew to support more than 60 users with 4 instruments over 2 campuses and more than 1000 hours of beam time booked each year. At RMIT he also led work integrated learning programs in the biopharmaceutical sciences and taught courses on haematology, drug development, drug regulation and clinical trials. Prior to RMIT, Matt was a postdoc and then instructor at The Centre for Platelet Function Studies at University of Massachusetts Medical School, which became the Centre for Platelet Research at Harvard Medical School.

Matthew’s research interest is in the field of thrombosis. It includes using flow cytometry of platelets to guide therapy in diabetes and heart disease, developing new and emerging anti-platelet strategies, and understanding the role of the interaction of platelet with other cells in the development of heart disease. Dr Linden leads funded projects which focus on this, but also collaborates on a diverse range of other projects involving flow cytometry.

Dr Rong LiuGraduating in Physics from the National University of Singapore, Rong has 26 years’ experience

on SIMS analysis of various types of materials. He has co-authored 67 published journal papers, and 67 conference presentations.

In 1984 Rong joined Tianjin Electronic Materials Research Institute working on application aspects of SIMS in microelectonic materials and related fields then in 1996 he was a Senior Visiting Scholar at Laval University, Canada. From 1998-2005, he had been with the Surface Science Lab of the National University of Singapore.

His research activities concentrate on application of SIMS in physics, chemistry, materials, and related fields. From 2005-2010, he worked as SIMS lab manager at University of Manitoba and had concentrated his effort on SIMS isotope ratio measurements for research projects in geological, archaeological and environmental sciences. Over the past few years Rong’s interests have turned to SIMS imaging application in metals and biomedical materials.

Assistant Professor Laure MartinLaure completed her PhD in Nancy at the Centre de Recherche

Pétrographique et Géochimique (CRPG, France) on the significance of zircon U-Pb ages in the metamorphic rocks from Naxos and Ikaria (Greece), after graduating in Earth Sciences at the University Paris XI in France. This gave the opportunity for Laure to work on the SIMS Cameca 1270 to perform U-Pb dating in zircon as well as oxygen isotopes in zircon and garnet.

She has mainly worked in experimental petrology, first at Macquarie University and then at the ANU, covering topics related to element cycling in subduction zones. Laure continued to work on natural rocks with the study of eclogites from various localities to understand fluid history in these rocks.

Laure has a broad geology background, but her speciality is in metamorphic petrology. She tries to combine fine textural analysis of minerals with in-situ chemical andisotopic analysis to reconstruct rock histories and answer questions such as element transfer in subduction zones, ore deposit formation and mountain belt evolutions.

Staff


Mr Francesc TintoFrancesc successfully completed a B.Sc. of Physics at the University

of Barcelona in Spain followed by an Engineering degree at the National School of Higher Education in Physics of Strasbourg (ENSPS), Louis Pasteur University, France. He completed his studies with the Master of Space Studies at the International Space University in Strasbourg, France.

During the last nine years Francesc has worked on various types of optical instruments in the Optical Instrumentation Department at the French Space Agency (CNES) in Toulouse, France. He was appointed as Camera Manager for the Venµs satellite project seven years ago, commencing with the preliminary design phase. Since then he has carried out the technical follow-up of the camera development which is now in the late integration and test phase. His responsibilities included the technical management of the camera with a team of CNES experts in coordination with the industrial prime contractor. The Venµs camera is an imaging super-spectral radiometer in the visible and near IR, Francesc was previously involved in the final testing and in-orbit commissioning of the Infrared Imaging Radiometer (IIR), an uncooled thermal IR radiometer onboard the Calipso satellite, as well as the development of a breadboard for a Static Fourier Transform spectrometer.

Ms Alysia BuckleyAlysia studied at UWA, graduating with a Bachelor of Science (Biomedical

Science) with Honours in Pharmacology (2007), where her study focused on the role of guidance cues in the developing retina. During this period, Alysia was first exposed to the CMCA, working on the BioRad UV Confocal microscope. Following this, she worked as a Graduate Research Assistant in the Spinal Cord Research Laboratory, within the School of Anatomy, Physiology and Human Biology from 2008 to 2012, where her interest was on the use of human bone marrow stromal cells in spinal cord injury repair.

Alysia started at the CMCA in July 2012 to provide assistance in the Optical and Confocal imaging area, and to provide backup support in Flow Cytometry. She is also fractionally appointed on an NHMRC research grant examining the role of epithelial integrity in asthma which will involve extensive immunolabelling and ex-vivo whole mount confocal and multiphoton microscopy.

IMAGE (L-R) / 100UM-THICK SECTIONS OF A NEW

PERENNIAL HERBACEOUS PASTURE LEGUME.

STEMS WERE PREPARED ON A VIBRATOME AND

IMAGES TAKEN ON THE ZEISS AXIOSKOP OPTICAL

MICROSCOPE. IMAGES: PETA CLODE.

THREE SEBACEOUS GLANDS SURROUND THE

HAIR FOLLICLE AND WILL EMPTY THEIR GREASY

GLOBULES (WHITE) ONTO THE HAIR BY PAUL RIGBY.

NANOFIBRES OF CHITOSAN, DERIVED FROM

CRUSTACEAN EXOSKELETONS. IMAGE BY MICHAEL

BRADSHAW.

TEETH OF CHITON, A PRIMITIVE MARINE MOLLUSC

THAT EATS ALGAE OFF THE ROCKS. IMAGE BY

JEREMY SHAW.

ANTARTIC 'HAIR GRASS' ROOT CROSS-SECTION,

SHOWING THE ARRANGEMENT OF CELLS. IMAGE

BY PETA CLODE.


Ms Elizabeth AlbertLiz joined CMCA as Executive Assistant to the Director in June 2011. She has

had a varied career working in senior administrative positions both in the UK and in Australia. Since coming to Perth Liz has held Executive Assistant/Personal Assistant positions in a range of industries, including gaming and hospitality, community aged care, community disability care and three universities in Perth. Liz has proven to be a valuable asset in the Centre through supporting the Director’s office and also fulfilling a key role in the administration team.

Dr Tamara AbelDr Tamara Abel was successful in her application for the position of Senior Research Officer, and is

looking forward to continuing to build her expertise in pre-clinical imaging to enhance bioimaging research at UWA. Tamara joined CMCA in 2010 on a contract basis to provide academic support and manage the microscopy and bioimaging facilities at CMCA@QEII. During this time, she has been instrumental in setting up WA’s first bioimaging facility to support interdisciplinary and multi-modal imaging of small animals using X-ray CT, MRI and multispectral optica imaging.

Tamara received her PhD with the Centre for Orthopaedic Research at The University of Western Australia in 2008, studying the molecular mechanisms underlying bone remodelling. She continued post-doctoral training at the centre focusing on studies to identify the molecular pathways regulating bone biology utilising animal models of bone disease. In 2010, she joined the Centre for Microscopy, Characterisation and Analysis. Tamara has extensive experience in imaging techniques, animal handling, sample preparation, data processing and analysis.

Staff ChangesSean WebbSean is the Centre Manager of the Centre for Microscopy, Characterisation and Analysis.

His career has progressed in business development, project and administration management roles through industries such as Aircraft Leasing and Operations, Finance and the Tertiary Education and Research Sector. Previously, he managed the WA Geothermal Centre of Excellence at UWA which was a collaborative Centre partnering with the CSIRO and Curtin University, supported by the WA Dept. of Commerce. Sean has gained over 18 years of experience through these roles and enjoys the challenge of understanding both the strategic and administrative aspects of an industry/ project which can then be used to achieve high performance.

Besides his commercial experience, he holds a BBS(Hons) degree, is a graduate of the Australian Institute of Company Directors, a Fellow of Finsia and an MBA graduate from UWA. He is also Chair of the SEA Board, the peak body for sustainable energy in Western Australia.


Staff Awards

Fellow of the Optical SocietyWinthrop Professor David Sampson, Director of the CMCA, was recently elected a fellow of the prestigious Optical Society of America (OSA). This was in recognition of his exceptional contributions to the development and applications of wave-guide optics for in-situ biomedical imaging.

This announcement coincides with the OSA’s annual publication of the Best of the Best global research in optics for the year. Research by Prof. Sampson’s team was featured in the publication and a related video, as one of the top three research articles. The research described the development and application of a microscope being put inside a standard hypodermic needle to enable 3-D scanning of tissue in-situ. This will be useful in diagnostics, research and surgery.

Professor Sampson’s commitment to the field of optics has helped UWA achieve the top ranking of five in Optical Physics in the Excellence in Research for Australia (ERA) results announced in December 2012.

Fellow of the UK Institute of PhysicsProfessor Martin Saunders has been awarded the title of Fellow of the UK Institute of Physics.

The Institute of Physics has a worldwide membership of around 40,000 comprising physicists from all sectors, as well as those with an interest in physics. It works to advance physics research, application and education; and engages with policy makers and the public to develop awareness and understanding of physics. Its publishing company, IOP Publishing, is a world leader in professional scientific communications.

AMMRF leadership in Australian microscopyIn October 2012, the Presidency of the Australian Microscopy and Microanalysis Society (AMMS) passed from Prof. Tim White (former Australian National University node director) to Prof. Martin Saunders, Deputy Director of the AMMRF at The University of Western Australia

Staff ListÌÌ W/Prof. David Sampson

(Director)ÌÌ Prof. Martin Saunders (Deputy

Director)ÌÌ Sean Webb (Centre Manager)ÌÌ Steve Parry (Laboratory

Manager)ÌÌ Dr Tamara AbelÌÌ David AdamsÌÌ Liz AlbertÌÌ Alysia BuckleyÌÌ Dr Lindsay ByrneÌÌ Asst/Prof. John CliffÌÌ Assoc/Prof. Peta ClodeÌÌ Dana Crisan

ÌÌ Peter DuncanÌÌ Dr Monica Gagliano (joint

appointment with UWA School of Animal Biology)

ÌÌ Francesc Tinto Garcia-Moreno (Technical Operations Manager)

ÌÌ Prof. Brendan GriffinÌÌ Jeanette HatchÌÌ Assoc/Prof. Andrew Johnson

(Honorary)ÌÌ Asst/Prof. Lecia KhorÌÌ Assoc/Prof. Matt KilburnÌÌ Lyn KirilakÌÌ Prof. John Kuo (Honorary)ÌÌ Tracey Lee-PullenÌÌ Assoc/Prof. Matthew Linden

ÌÌ Dr Rong LiuÌÌ Asst/Prof. Laure MartinÌÌ Asst/Prof. Janet MuhlingÌÌ John MurphyÌÌ Tracey O’KeefeÌÌ Dr Anthony ReederÌÌ Assoc/Prof. Paul RigbyÌÌ Asst/Prof. Michael StatÌÌ Dr Jeremy ShawÌÌ Dr Brian SkeltonÌÌ Asst/Prof. Alexandra SuvorovaÌÌ Dr David Wacey (joint appointment

with UWA School of Earth and Environment)

(UWA). Prof. Saunders heads electron microscopy at UWA and previously acted as Editor of the AMMS newsletter for almost ten years. The continued close affiliation between AMMS, Australia’s peak scientific body representing microscopy, and the AMMRF, its core microscopy infrastructure provider, will further the promotion of microscopy on the national stage.


Conferences and visits


IMAGE / 100UM-THICK SECTIONS OF A NEW PERENNIAL

HERBACEOUS PASTURE LEGUME.STEMS WERE PREPARED ON

A VIBRATOME AND IMAGES TAKEN ON THE ZEISS AXIOSKOP

OPTICAL MICROSCOPE. IMAGES: PETA CLODE.

IMAGE / HUMAN OPTIC NERVE IMAGE BY

ALISON JENNINGS, ACQUIRED AT CMCA.


Perth hosts the largest microscopy and nanotechnology event ever held in AustraliaMore than 1100 specialists from around the world convened at the Perth Convention and Exhibition Centre earlier this year for a combined congress comprising the 1Oth Asia-Pacific Microscopy Conference, the 2012 International Conference on Nanoscience and Nanotechnology, and the 22nd Australian Conference on Microscopy and Microanalysis.

Delegates had exposure to cutting edge tools and technology at the

concurrent 100 booth exhibition, which covered two enormous pavilions at the PCEC, or around 6000 square metres. Co-chairman of the organising committee was CMCA’s Professor Brendan Griffin. Brendan said this was a truly unique science and technology forum, combining for the first time three events into one mega congress. It was also the first time in the 40 year history of the Asia Pacific Microscopy Conference that it’s been hosted in Australia, and more than 1100 people from around the globe chose to attend, including some of the world’s best scientists. It provided an exceptional opportunity to showcase

Australia’s expertise in the field. Of the 200 eminent scientists invited to speak, around one third were from our local scientific community.

With around 870 papers presented in nine parallel sessions over five days, Professor Griffin said the sheer breadth of the conference reflected the wide range of disciplines and lightning pace of progress in the field.

The official opening address was delivered by the Governor of Western Australia, His Excellency Mr Malcolm James McCusker AO CVO QC, reinforcing the significance of the event to the state.

32 | cmca.uwa.edu.au The University of Western Australia | 32

Overseas VisitorsVisitors to CMCA January 2012 – China delegationA party of delegates from China attending the Australia – China Joint Centre and Alliance for Energy and Mining, and the 1st Technical Workshop, were given a tour of the CMCA.

July 2012 – Worldwide Universities Network A former UWA graduate, Dr Nicole Hondow from the University of Leeds, visited the Centre for six weeks through a Worldwide Universities Network mobility grant. Dr Hondow worked on the development of specimen preparation protocols and miscroscopy techniques for analysing the structure of nanoparticle assemblies for use in nano medicine.

The Centre’s Deputy Director, Professor Martin Saunders, said it was likely a PhD student exchange program would be set up between the CMCA and the Leeds electron microscopy group.

From the University of York, Dr Roland Kroeger and Ms Renee van der Locht are spending four weeks at the Centre to research coral biomineralisation with Winthrop Professor Malcolm McCulloch of UWA’s Ocean Institute. They are at UWA until 4 July thanks to a York scheme to promote collaborations with Worldwide Universities Network partners.

The CMCA supports research across the University, the Australian community and internationally in natural, agricultural, physical, life and biomedical sciences and engineering.

Research in the biosciences involves understanding the structural, immunological and compositional properties of cells and tissues. In Earth and environmental sciences, analysing and characterising the minerals and microstructures of rocks and soils increases knowledge of the planet’s past and guides the sustainable development of resources. In physical science, research involves the characterisation of the structure, composition and chemistry of materials down to the nano or atomic scales.

Through its Research Mobility Program, Worldwide Universities Network supports personal and academic growth, enabling postgraduate students and staff to work at member universities. The Network enhances learning and internationalises curricula through the development of e-learning theory, practice and programs and organises regular online seminars delivered by leading Worldwide Universities Network academics with themes and topics ranging across the research spectrum.

UWA will encourage its researchers to benefit from the association with Worldwide Universities Network by providing funding on a competitive basis to support staff and postgraduate students to initiate, expand and maintain collaborative research projects with Network partners.

Worldwide Universities Network currently consists of the Universities of Alberta; Bergen; Bristol; California, San Diego; Illinois, Urbana-Champaign; Leeds, Nanjing, Pennsylvania State; Sheffield; Southampton; Sydney; Utrecht; Washington, Seattle; Wisconsin, Madison; York; Zhejiang and UWA.

May 2012 – Cancer Council Western AustraliaIn May 2012 a group from the Cancer Council WA visited CMCA@QEII. The visit was organised by Assoc. Professor Fiona Pixley from the Pharmacology, Pharmacy and Anaesthesiology Unit of the School of Medicine and Pharmacology. Assoc. Professor Pixley combines a broad range of cytometry techniques at CMCA to further her research into understanding how cancer spreads.

September 2012 – The Hon Martin FergusonThe Hon Martin Ferguson, MP, Minister for Resources and Energy, Minister for Tourism visited the CMCA in September 2012 as part of a visit to the University. He showed a particular interest in the CAMECA ion probe instruments.

November 2012 – Professor Geoffrey Laurent, Centre for Cell Therapy and Regenerative MedicineProfessor Geoffrey Laurent from the Centre for Cell Therapy and Regenerative Medicine Toured CMCA@QEII in November 2012. Professor Laurent has recently been recruited from University College London where he led a world recognized research and training centre. His appointment will assist in attracting young rising stars as well as other world leaders who will strengthen WA’s science base and help foster global collaborative networks.

2010 p25

2011 p30

2011 p34

2012 p39

IMAGE / MB-10 MARBLE BAR CHERT

TAKEN AT CMCA BY DR JANET MUHLING.


Journal Papers

Top cited papers 2008 - 2012Highly cited papers from CMCA“High citations of a publication are a key indicator of the relative importance of a work in science. For CMCA the following table captures publications with a greater than ten cites per annum, and includes CMCA staff (2008 to 2012) and CMCA User publications (2008-2012).”

ÌÌ B.J. Wood, J. Wade and M.R. Kilburn, Core formation and the oxidation state of the Earth: Additional constraints from Nb, V and Cr partitioning. Geochimica et Cosmochimica Acta 72(5): 1415-1426, 2008.

ÌÌ J. Hamzah, M. Jugold, F. Kiessling, P.J. Rigby, M. Manzur, H.H. Marti, T. Rabie, S. Kaden, H.J. Gröne, G.J. Hämmerling, B. Arnold and R. Ganss, Vascular normalization in Rgs5-deficient tumours promotes immune destruction, Nature, 453: 410-454, 2008.

ÌÌ B. Rasmussen, I.R. Fletcher, J. Brocks and M.R. Kilburn, Reassessing the first appearance of eukaryotes and cyanobacteria, Nature, 455: 1101-1104, 2008.

ÌÌ H.R. Chinnery, E. Pearlman and P.G. McMenamin, Cutting edge: membrane nanotubes in vivo: a feature of MHC class II+ cells in the mouse cornea, The Journal of Immunology, 180: 5779-5783, 2008.

ÌÌ P. Salama, M. Phillips, F. Grieu, M. Morris, N. Zeps, D. Joseph, C. Platell and B. Lacopetta, Tumour-infiltrating FOXP3+ T regulatory cells show strong prognostic significance in colorectal cancer, Journal of Clinical Oncology, 27(2): 186-192, 2009.

ÌÌ W.M. Khairul, M.A. Fox, N.N. Zaitseva, M. Gaudio, D.S. Yufit, B.W. Skelton, A.H. White, J.A.K. Howard, M.I. Bruce and P.J. Low, Transition metal alkynyl complexes by transmetallation from Au(Cë_CAr)(PPh3) (Ar = C6H5 or C 6H4Me-4), Dalton Transactions 4: 610-620, 2009.

ÌÌ M. Paskevicius, D.A. Sheppard and C.E. Buckley, Thermodynamic changes in mechanochemically synthesized magnesium hydride nanoparticles, Journal of the American Chemical Society, 132: 5077-5083, 2010.

ÌÌ P. Che, J.D. Bussell, W. Zhou, G.M. Estavillo, B.J. Pogson and S.M. Smith, Signaling from the endoplasmic reticulum activates brassinosteroid signaling and promotes acclimation to stress in Arabidopsis, Science Signaling, 3(141):ra69, 2010.

ÌÌ W.L. Zhu, G.A. Gaetani, F. Fusseis, L.G.J. Montesi, and F. De Carlo, Microtomography of partially molten rocks: Three-dimensional melt distribution in mantle peridotite, Science, 332: 88-91, 2011.

ÌÌ D. Wacey, M.R. Kilburn, M. Saunders, J Cliff and M.D. Brasier, Microfossils of sulphur-metabolizing cells in 3.4-billion-year-old rocks of Western Australia, Nature Geoscience, 4(10): 698-702, 2011.

ÌÌ J.P. Williamson, R.A. McLaughlin, W.J. Noffsinger, A.L. James, V.A. Baker, A. Curatolo, J.J. Armstrong, A. Regli, K.L. Shepherd, G.B. Marks, D.D. Sampson, D.R. Hillman and P.R. Eastwood, Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography, American Journal of Respiratory and Critical Care Medicine, 183(5): 612-619, 2011.

2011Journal Publications1. C.W. Evans, M.Fitzgerald, T.D. Clemons,

M.J. House, B.S. Padman, J.A. Shaw, M. Saunders, A.R. Harvey, B. Zdyrko, I.A. Luzinov, G.A. Silva, S.A. Dunlop and K.S. Iyer, Multimodal analysis of PEI-mediated endocytosis of nanoparticles in neural cells, ACS Nano, 5(11): 8640-8648, 2011.

2. A.P. Roberts, G. Grayson, V.J. Challis, L.C. Zhang, J.F. Grotowski, G.B.Schaffer and T.B. Sercombe, Elastic moduli of sintered powders with application to components fabricated using selective laser melting, Acta Materialia, 59: 5257-5265, 2011.

3. X. Xu, H. Yang, Y. Liu, Y. Zheng, L. Li, Y. Ji and X. Han, Formation mechanism of novel two-dimensional single crystalline dendritic copper plates in an aqueous environment, Acta Materialia, 59: 7177-7188, 2011.

4. M. K. Abdul Hamid and G.W. Stachowiak, The effects of grit particle size on frictional characteristics of automotive braking system, Advanced Materials Research, 189-193: 3511-3516, 2011.

5. R. Sultana, J. Yang and X. Hu, Processing of Layered Hydroxyapatite Ceramic Composites, Advanced Materials Research, 275: 143-146, 2011.

6. R.M. Duff, V. Tay, P. Hackman, G. Ravenscroft, C. McLean, P. Kennedy, A. Steinbach, W. Schöffler, P.F.M. Van Der Ven, D.O. Fürst, J. Song, K. Djinović-Carugo, S. Penttilä, O. Raheem, K. Reardon, A. Malandrini, S. Gambelli, M. Villanova, K.J. Nowak, D.R. Williams, J.E. Landers, R.H. Brown Jr, B. Udd and N.G. Laing, Mutations in the N-terminal actin-binding domain of filamin C cause a distal myopathy, American Journal of Human Genetics, 88(6): 729-740, 2011.

7. A.J. Lee, V.A. Lambermont, J.J. Pillow, G.R. Polglase, I. Nitsos, J.P. Newnham, M.W. Beilharz, S.G. Kallapur, A.H. Jobe and B.W. Kramer, Fetal responses to lipopolysaccharide-induced chorioamnionitis alter immune and airway responses in 7-week-old sheep, American Journal of Obstetrics and Gynecology, 204(364): e17-24, 2011.

8. S.G. Kallapur, B.W. Kramer, I. Initso, J.J. Pillow, J.J.P. Collins, G.R. Polglase, J.P. Newnham and A.H. Jobe, Pulmonary and systemic inflammatory responses to intra-amniotic IL-1{alpha} in fetal sheep, American Journal of Physiology Lung Cellular Molecular Physiology, 301(3): L285-295, 2011.

9. J.P. Williamson, R.A. McLaughlin, W.J. Noffsinger, A.L. James, V.A. Baker, A. Curatolo, J.J. Armstrong, A. Regli, K.L. Shepherd, G.B. Marks, D D. Sampson, D.R. Hillman and P.R. Eastwood, Elastic properties of the central airways in obstructive lung diseases measured using anatomical optical coherence tomography, American Journal of Respiratory and Critical Care Medicine, 183: 612-619, 2011.

10. R. Gulliver, S. Baltic, N.L. Misso, C.M. Bertram, P.J. Thompson and M. Fogel-Petrovic, Lys-des[Arg 9]-bradykinin alters migration and production of interleukin-12 in monocyte-derived dendritic cells, American Journal of Respiratory Cell and Molecular Biology, 45(3): 542-549, 2011.

11. L. Balaguera-Cortes, K.E. Wallman, T.J. Fairchild and K.J. Guelfi, Energy intake and appetite-related hormones following acute aerobic and resistance exercise, Applied Physiology Nutrition and Metabolism, 36: 958-966, 2011.

12. S. Lo, J. Steer and D.A. Joyce, Tumor necrosis factor-alpha promotes survival in methotrexate-exposed macrophages by an NF-kappaB-dependent pathway, Arthritis Research and Therapy, 13(1): R24, 2011.

13. M.D. Brasier, R. Matthewman, S. McMahon and D. Wacey, Pumice as a remarkable substrate for the origin of life, Astrobiology, 11(7): 725-735, 2011.

14. L.E. Wedlock and S.J. Berners-Price, Recent advances in mapping the sub-cellular distribution of metal-based anticancer drugs, Australian Journal Chemistry, 64 : 692-704, 2011.


32. N. McLouhglin, D. Wacey, C. Kruber, M.R. Kilburn, I.H. Thorseth and R.B. Pedersen, A combined TEM and NanoSIMS study of endolithic microfossils in altered seafloor basalt, Chemical Geology, 289: 154-162, 2011.

33. V.M. Pinto, L.A. Hartmann, J.O.S. Santos, N.J. McNaughton and W. Wildner, Zircon U–Pb geochronology from the Paraná bimodal volcanic province support a brief eruptive cycle at ~135 Ma, Chemical Geology, 281: 93-102, 2011.

34. A. Cornejo, L. Gao, W. Zhang, R.R. Varsani, M. Saunders, K.S. Iyer, R. Francis, C.L. Raston and H.T. Chua, Methane to zero emission hydrogen with carbon captured as pure spheroidal nanomaterials, Chemistry: A European Journal, 17: 9188-9192, 2011.

35. B. Rasmussen, I.R. Fletcher and J.R. Muhling, Response of xenotime to prograde metamorphism, Contributions to Mineralogy and Petrology, 162: 1259-1277, 2011.

36. N.L. Patten, A.S.J. Wyatt, R.J. Lowe and A.M. Waite, Uptake of picophytoplankton, bacterioplankton and virioplankton by a fringing coral reef community (Ningaloo Reef, Australia), Coral Reefs, 30/3: 555-567, 2011.

37. P.L. Clode, K. Lema, M. Saunders and S. Weiner, Skeletal mineralogy of newly setting Acropora millepora (Scleractinia) coral recruits, Coral Reefs, 30: 1-8, 2011.

38. C. Bullen, P. Zijlstra, E. Bakker, M. Gu and C. Raston, Chemical kinetics of gold nanorod growth in aqueous CTAB solutions, Crystal Growth & Design, 11: 3375-3380, 2011.

39. A. Baynton, T. Radomirovic,a M.I. Ogden, C.L. Raston, W. R. Richmond and F. Jones, Small molecules induce mesocrystal formation: nanoparticle aggregation directed by self-assembling calixarenes, CrystEngComm, 13: 109-112, 2011.

40. D.H. Brown and B.W. Skelton, Nickel complexes of a bis(benzimidazolin-2-ylidene)pyridine pincer ligand with four- and five-coordinate geometries, Dalton Transactions, 40: 8849-8858, 2011.

41. J. Fang, G. Yanglong, L. Guanzhong, C.L. Raston and K. Swaminathan Iyer, Enhancement of quantum yield of LaPO4: Ce3+: Tb3+ nanocrystals by carbon nanotube induced suppression of the 1-dimensional growth, Dalton Transactions, 40: 3122-3124, 2011.

42. L.A. Casson, S. Muzzioli, P. Ralteri, B.W. Skelton, S. Stagni, M. Massi and D.H. Brown, N-Heterocyclic carbenes as p*-acceptors in luminescent Re(I) triscarbonyl complexes, Dalton Transactions, 40: 11960-11967, 2011.

15. J. Miyazaki, B.H. Tan, S.G. Errington and J.J.S. Kuo, Bacterial endophyte in Macropidia fuliginosa :its localisation and eradication from in vitro cultured basal-stem callus, Australian Journal of Botany, 59: 363-368, 2011.

16. M. Landers, M. Grafe, R.J. Gilkes, M. Saunders and M. Wells, Nickel distribution and speciation in rapidly dehydroxylated goethite in oxide-type lateritic nickel ores: XAS and TEM spectroscopic (EELS and EFTEM) investigation, Australian Journal of Earth Sciences, 58(7): 645-765, 2011.

17. A.L. Magno, E. Ingley, S.J. Brown, A.D. Conigrave, T. Ratajczak and B.K.Ward, Testin, a novel binding partner of the calcium-sensing receptor, enhances receptor-mediated Rho-kinase signalling, Biochemical and Biophysical Research Communications, 412 (4): 584-589, 2011.

18. J.F.V. Della Vergiliana, S. Lansley, A.L. Tan, J. Creaney, Y.C.G. Lee and G.A Stewart, Mesothelial cells activate the plasma kallikrein-kinin system during pleural inflammation, Biological Chemistry, 392: 633-642, 2011.

19. R.B. Thornton, P.J. Rigby, S.P. Wiertsema, P. Filion, J. Langlands, H.J. Coates, S. Vijayasekaran, A.D. Keil and P.C. Richmond, Multi-species Bacterial Biofilm and Intracellular Infection in Otitis Media, BMC Pediatrics, 11(94): 1-10, 2011.

20. C. Balaratnasingam, S.J. Cringle, N. Fatehee, W.H. Morgan and D.Y. Yu, Comparison of fluctuating and sustained neural pressure perturbations on axonal transport processes in the optic nerve, Brain Research, 1417: 67-76, 2011.

21. F.M. Wood, N. Giles, A. Stevenson, S. Rea and M. Fear, Characterisation of the cell suspension harvested from the dermal epidermal junction using a ReCell(®) kit, Burns, 38(1): 44-51, 2012.

22. C. Jackaman and D.J. Nelson, Intratumoral interleukin-2/agonist CD40 anitbody drives CD4+-independent resolution of treated tumors and CD4+-dependent systemic and memory responses, Cancer Immunol Immunother, 61: 549-560, 2011.

23. S. Lo, J. Steer and D.A Joyce, TNF-α renders macrophages resistant to a range of cancer chemotherapeutic agents through NF-κB-mediated antagonism of apoptosis signalling, Cancer Letters, 307: 80-92, 2011.

24. E. Thomas, N. Zeps, M. Cregan, P. Hartman and T. Martin, 14-3-3s (sigma) regulates proliferation and differentiation of multipotent p63-positive cells isolated from human breastmilk, Cell Cycle, 10(2): 278-84, 2011.

25. E. Thomas, N. Zeps, P. Rigby and P. Hartmann, Reactive oxygen species initiate luminal but not basal cell death in cultured human mammary alveolar structures: a potential regulator of involution, Cell Death & Disease, 2: e189, 2011.

26. A.D. Martin and C.L. Raston, Multifunctional p-phosphonated calixarenes, Chemical Communications, 47: 9764-9772, 2011.

27. J. Fang, R. Pillai, M. Saunders, J. Zou, D. Lorenser, D.D. Sampson, Y. Guo, G. Lu, and K. Swaminathan Iyer, Room temperature synthesis of upconversion fluorescent nanocrystals, Chemical Communications, 47(36): 10043-10045, 2011.

28. J. Zou, A.D. Martin, B. Zdyrko, I. Luzinov, C. L. Raston and K. Swaminathan Iyer, Pd-induced ordering of 2D Pt nanoarrays on phosphonated calix[4]arenes stabilised graphenes, Chemical Communications, 47: 5193-5195, 2011.

29. J. Zou, S.G. Stewart, C.L. Raston and K. Swaminathan Iyer, Surface oxygen triggered size change of palladium nano-crystals impedes catalytic efficacy, Chemical Communications, 47: 1803-1805, 2011.

30. M. Bradshaw, J. Zou, L. Byrne, K. Swaminathan Iyer, S.G. Stewart and C.L. Raston, Pd(II) conjugated chitosan nanofibre mats for application in Heck cross-coupling reactions, Chemical Communications, 47: 12292-12294, 2011.

31. C. Bullen, M.J. Latter, N. J. D’Alonzo, G. J. Willis and C.L. Raston, A seedless approach to continuous flow synthesis of gold nanorods, Chemical Communications, 47: 4123-4125, 2011.

Total 152

Biological/biomedical sciences 75

Physical sciences 55

Environmental/geosciences 22

2011 Journal Papers


43. S. Rubanov and A. Suvorova, Ion implantation in diamond using 30 keV Ga+ focused ion beam, Diamond and Related Materials, 20: 1160-1164, 2011.

44. D. Wacey, M. Saunders, M.D. Brasier and M.R. Kilburn, Earliest microbially mediated pyrite oxidation in ~3.4 billion-year-old sediments, Earth and Planetary Science Letters, 301: 393-402, 2011.

45. B. Godel, Z. Seat, W. Maier and S-J. Barnes, The Nebo-Babel Ni-Cu-PGE Sulfide Deposit (West Musgrave Block, Australia): Pt. 2. Constraints on Parental Magma and Processes, with Implications for Mineral Exploration, Economic Geology, 106: 557-584, 2011.

46. J.L. Mair, G.L. Farmer, D.I. Groves, C.J.R. Hart and R.J. Goldfarb, Petrogenesis of postcollisional magmatism at Scheelite Dome, Yukon, Canada: Evidence for a lithospheric mantle source for magmas associated with intrusion-related gold systems, Economic Geology, 106: 451-480, 2011.

47. Z. Seat, M.A.M. Gee, B.A. Grguric, S.W. Beresford and N.V. Grassineau, The Nebo-Babel Ni-Cu-PGE Sulfide Deposit (West Musgrave, Australia): Pt. 1. U/Pb Zircon Ages, Whole-Rock and Mineral Chemistry, and O-Sr-Nd Isotope Compositions of the Intrusion, with Constraints on Petrogenesis, Economic Geology, 106: 527-556, 2011.

48. M. Wang, H. Yang and Y. Liu, Current oscillations during potentiostatic anodisation of tine in alkaline electrolytes, Electrochimica Acta, 56: 7051-7057, 2011.

49. M. Wang, Y. Liu, D. Xue, D. Zhang and H. Yang, Preparation of nanoporous tin oxide by electrochemical anodization in alkaline electrolytes, Electrochimica Acta, 56(24): 8797-8801, 2011.

50. H. Li, X. Ge, S. Han, K. Sivasithamparam and M.J. Barbetti, Histological responses of host and non-host plants to Hyaloperonospora parasitica, European Journal of Plant Pathology, 129: 221-232, 2011.

51. G.W. Plant, A.R. Harvey, S.G. Leaver and S.V. Lee, Olfactory ensheathing glia: Repairing injury to the mammalian visual system, Experimental Neurology, 229: 99-108, 2011.

52. E.S.M. Ang, X. Yang, H. Chen, Q. Liu, M.H. Zheng and J. Xu, Naringin abrogates osteoclastogenesis and bone resorption via the inhibition of RANKL-induced NH-ΚB and ERK activation, FEBS Letters, 585(17): 2755-2762, 2011.

53. O. Rackham, A-M.J. Shearwood, R. Thyer, E. McNamara, S.M.K. Davies, B.A. Callus, A. Miranda-Vizuete, S.J. Berners-Price, Q. Heng, E.S.J. Arnér and A. Filipovska, Substrate and inhibitor specificities differ between human cytosolic and mitochondrial thioredoxin reductases: Implications for development of specific inhibitors, Free Radical Biology & Medicine, 50(6): 689-99, 2011.

54. R. Chen, M. Wilson, Y.K. Leong, P. Bryant, H. Yang and D.K. Zhang, Preparation and rheology of biochar, lignite char and coal slurry fuels, Fuel, 90: 1689-0695, 2011.

55. A.A. Nemchin, M.J. Whitehouse, M.L. Grange and J.R.Muhling, On the elusive isotopic composition of lunar Pb, Geochimica et Cosmochimica Acta, 75: 2940-2964, 2011.

56. B. Rasmussen, I.R. Fletcher, J.R. Muhling, C.J. Gregory and S.A. Wilde, Metamorphic replacement of mineral inclusions in detrital zircon from Jack Hills, Australia: Implications for the Hadean Earth, Geology, 39: 1143-1146, 2011.

57. J. Fang, G. Yanglong, L. Guanzhong, C.L. Raston and K. Swaminathan Iyer, Instantaneous crystallization of ultrathin one-dimensional fluorescent rhabdophane nanowires at room temperature, Green Chemistry, 13: 817-819, 2011.

58. P. Salama, M. Phillips, C. Platell and B. Iacopetta, Low expression of Granzyme B in colorectal cancer is associated with signs of early metastastic invasion, Histopathology, 59: 207-215, 2011.

59. D.D. Sampson, Optical Bioimaging 2010: Seeing more, deeper, faster, IEEE Photonics Journal, 3(2): 278-283, 2011.

60. C. Jackaman, S. Cornwall, P.T. Graham and D.J. Nelson, CD-40 activated B cells contribute to mesothelioma tumor regression, Immunology and Cell Biology, 89: 255-267, 2011.

61. J.S. Croser, M.M. Lulsdorf, R.K. Grewal, K.M. Usher and K.H.M. Siddique, Isolated microspore culture of chickpea (Cicer arientinum L.): inductino of adrogenesis and cytological analysis of early haploid divsions, In Vitro Cellular and Developmental Biology: Plant, 47: 357-368, 2011.

62. Z. Liu, Z. Wu, H. Yang, Y. Liu, W. Wang, X. Ma and G. Wu, Martensitic transformation and magnetic propertiesin ferromagnetic shape memory alloy Ni43Mn46Sn11-xSix, Intermetallics, 19: 1605-1611, 2011.

63. Z. Wu, Z. Liu, H. Yang, Y. Liu, Z. Wu and R.C. Woodward, Metallurgical origin of the effect of Fe dopig on the martensitic and magnetic transformation behaviours of Ni50Mn40-xSn10Fex magnetic shape memory alloys, Intermetallics, 19: 445-452, 2011.

64. H.Y. Tian, C.E. Buckley, M. Paskevicius, D.A. Sheppard, S.B. Wang, C.J. Webb, E.M. Gray, Nanoscale cobalt doped carbon aerogel: microstructure and isosteric heat of hydrogen adsorption, International Jounal of Hydrogen Energy, 36: 10855-10860, 2011.

65. Z. Lin, K.L. Solomon, X. Zhang, N.J. Pavlos, T. Abel, C. Willers, K.Dai, J. Xu, Q. Zheng and M. Zheng, In vitro evaluation of natural mirine sponge callagen as a scaffold for bone tissue engineering, International Journal of Biological Sciences, 7(7): 968-977, 2011.

66. M.P. Pitt, M. Paskevicius, C.J. Webb, M.H. Sorby, S. Delleda, T.R. Jensen,B.C. Hauback, C.E. Buckley and E. MacA. Gray, Nanoscopic Al1-xCex phases in the NaH + Al + 0.02CeCl3 system, International Journal of Hydrogen Energy, 36: 8403-8411, 2011.

67. P.M.L. Hedberg, P. Peres, J.B. Cliff, F. Rabemananjara, S. Littmann, H. Thiele, C. Vincent and N. Albert, Improved particle location and isotopic screening measurements of sub-micron sized particles by secondary ion mass spectrometry, Journal of Analytical Atomic Spectrometry, 26: 406-413, 2011.

68. E. Chan, D. Cadosch, O.P., Gautischi, K., Sprengel and L. Filgueira, Influence of metal ions on human lymphocytes and the generation of titanium-specific T-lymphocytes, Journal of Applied Biomaterials and Biomechanics, 9(2): 137-143, 2011.

69. C.F. Maitland, C.E. Buckley, B.H. O’Connor, P.D. Butler and R.D. Hart, Characterization of the pore structure of metakaolin-derived geopolymers by neutron scattering and electron microscopy, Journal of Applied Crystallography, 44: 694-707, 2011.

70. P.S.S. Rama Krishnan, M. Arredondo, M. Saunders, Q.M. Ramasse, N. Valanoor and P. Munroe, Microstructural analysis of ferromagnetic-multiferroic epitaxial heterostructure interfaces, Journal of Applied Physics, 109: art. No. 034103, 2011.

71. M.B. Dalrymple, W.C. Jaeger, K.A. Eidne and K.D. Pfleger, Temporal profiling of orexin receptor-arrestin-ubiquitin complexes reveals differences between receptor subtypes, Journal of Biological Chemistry, 286(19): 16726-16733, 2011.


93. S.M. Paterson, J. Clark, K.A. Stubbs, T.V. Chirila and M.V. Baker, Carbohydrate-Based Crosslinking Agents: Potential Use in Hydrogels, Journal of Polymer Science Part A: Polymer Chemistry, 49(20): 4312-4315, 2011.

94. T.J. Aitcheson, M. Ginic-Markovic, M. Saunders, P. Fredericks, S. Valiyaveettil, J.G. Matisons and G.P. Simon, Polymer Brushes on Multi-Walled Carbon Nanotubes by Activators Regenerated by Electron Transfer for Atom Transfer Radical Polymerization, Journal of Polymer Science Part A; Polymer Chemistry, 49(10): 4283-4291, 2011.

95. C.J. Chernicoff, E.O. Zappettini, J.O.S. Santos, E. Belousova and N.J. McNaughton, Hf isotope study of Palaeozoic metaigneous rocks of La pampa province and implications for the occurrence of juvenile early Neoproterozoic (Tonian) magmatism in south-central Argentina, Journal of South American Earth Sciences, 32: 477-484, 2011.

96. M.P.S. Zuquim, R.A.J. Trouw, C.C. Trouw and E. Tohver, Structural evolution and UePb SHRIMP zircon ages of the Neoproterozoic Maria da Fé shear zone, central Ribeira Belt - SE Brazil, Journal of South American Earth Sciences, 31: 199-213, 2011.

97. P. Saxena, O.M. Shaw, N.L. Misso, A. Naran, J. Shehatha, M.A. Newman, Y. d’Udekem, P.J. Thompson and I.E. Konstantinov, Remote ischemic preconditioning stimulus decreases the expression of kinin receptors in human neutrophils, Journal of Surgical Research, 171: 311-316, 2011.

98. Z. Liu, S. Shao, X. Hu and X. Wang, Surface Modification and Microstructure Design of Alumina Ceramics, Journal of the American Ceramic Society, 94(9): 2764-2766, 2011.

99. J.-Z. Yang, R. Sultana, X.-Z. Hua and Z.-H. Huangb, Porous hydroxyapatite coating on strong ceramic substrate fabricated by low density slip coating-deposition and coating-substrate co-sintering, Journal of the European Ceramic Society, 31: 2065-2071, 2011.

100. S. Dev, K.S. Iyer and C.L. Raston, Nanosized drug formulations under microfluidic continuous flow, Lab on a Chip, 11: 3214, 2011.

101. E-J. Teh, Y-K. Leong and Y. Liu, Isomerism and solubility of benzene mono- and dicarboxylic acid: its effect on alumina dispersions, Langmuir, 27(1): 49-58, 2011.

102. J. Scott, J. Muhling, I. Fletcher, M. Billia, J.M. Palin, T. Elliot and C. Gunter, The relationship of Palaeozoic metamorphism and S-type magmatism on the paleo-Pacific Gondwana margin, Lithos, 127: 522-534, 2011.

82. M. Gagliano, A.K. Lema, M. Depczynski and S. Whalan, Use it and lose it: lipofuscin accumulation in the midbrain of a coral reef fish, Journal of Fish Biology, 78: 659-666, 2011.

83. Y. Liu, N. Jehanathan and J. Dell, Thermally induced damages of PECVD SiNx thin films, Journal of Materials Research, 26(19): 2552-2557, 2011.

84. M. Lai, G. Parish, Y. Liu, J.M. Dell and A.J. Keating, Development of an alkaline-compatible porous-silicon photolithographic process, Journal of Microelectromechanical Systems, 20(2): 418-422, 2011.

85. P.L. Santa Maria, S.L. Redmond, M.D. Atlas and R. Ghassemifar, Keratinocyte growth factor 1, fibroblast growth factor 2 and 10 in the healing tympanic membrane following perforation in rats, Journal of Molecular Histology, 42(1): 47-58, 2011.

86. R.J. Marano and S.L. Redmond, In vitro cultured primary cells from a human utricle explant possesses hair cell like characteristics, Journal of Molecular Histology, 42: 365-370, 2011.

87. S.L. Redmond, B. Levin, K.A. Heel, M.D. Atlas and R.J. Marano, Phenotypic and genotypic profile of human tympanic membrane derived cultured cells, Journal of Molecular Histology, 42(1): 15-25, 2011.

88. A. Dodd and M. Saunders, Synthesis of rare earth hydroxide nanorods by room temperature reaction of oxide precursors with water, Journal of Nanoparticle Research, 13(6): 2633-2639, 2011.

89. M.I. Bruce, J.C. Morris, C.R. Parker and B.W. Skelton, Nucleophilic properties of Ru(CΚCH)(dppe)Cp*: Synthesis and structureof Ru{c=C]CArC(O)C(O)O}(dppe)Cp* [Ar = 2,4-(NO2)2C6H3], Journal of Organometallic Chemistry, 696: 3292-3295, 2011.

90. M.I. Bruce, N. Scoleri and B.W. Skelton, Lithiation of diynyl-ruthenium complexes: Routes to novel metallated functional diynes, Journal of Organometallic Chemistry, 696: 3473-3482, 2011.

91. M. Paskevicius, H-Y. Tian, D.A. Sheppard, C.J. Webb, M.P. Pitt, E.M. Gray, N.M. Kirby and C.E. Buckley, Magnesium Hydride Formation within Carbon Aerogel, Journal of Physical Chemistry C, 115: 1757-1766, 2011.

92. S.J. Purdy, J.D. Bussell, D.C. Nelson, D. Villadsen and S.M. Smith, A nuclear-localized protein, KOLD SENSITIV-1, affects the expression of cold-responsive genes during prolonged chilling in Arabidopsis, Journal of Plant Physiology, 168(3): 263-269, 2011.

72. B.C. Quirk, R.A. McLaughlin, A. Curatolo, R.W. Kirk, P.B. Noble and D.D. Sampson, In situ imaging of lung alveoli with an OCT needle probe, Journal of Biomedical Optics, 16(3): art. 036009 (4pp, 2011.

73. B.F. Kennedy, A. Curatolo, T.R. Hillman, C.M. Saunders and D.D. Sampson, Speckle reduction in optical coherence tomography images using tissue viscoelasticity, Journal of Biomedical Optics, 16 (2): 020506-1-3, 2011.

74. B.R. Klyen, T. Shavlakadze, H.D. Radley-Crabb, M.D. Grounds and D.D. Sampson, Identification of muscle necrosis in the mdx mouse model of Duchenne muscular dystrophy using three-dimensional optical coherence tomography, Journal of Biomedical Optics, 16(7): art. 076013 (9pp), 2011.

75. Y.M. Liew, R.A. McLaughlin, F.M.Wood and D.D. Sampson, Reduction of image artifacts in three-dimensional optical coherence tomography of skin in vivo, Journal of Biomedical Optics, 16(11): 116018, 2011.

76. K.E. Mackie, Z. Zhou, P. Robbins, M. Bulsara and M.H. Zheng, Histopathology of femoral head donations: A retrospective review of 6161 cases, Journal of Bone and Joint Surgery-Series A, 93(16): 1500-1509, 2011.

77. N.G. Sampaio, W. Yu, D. Cox, J. Wyckoff, J. Condeeli, E.R. Stanley and F.J. Pixley, Phosphorylation of CSF-1R Y721 mediates its association with PI3K to regulate macrophage motility and enhancement of tumor cell invasion, Journal of Cell Science, 124(12): 2021-2031, 2011.

78. S.M. Lansley, R.G. Searles, A. Hoi, C. Thomas, H. Moneta, S.E. Herrick, P.J. Thompson, M. Newman, G.F. Sterrett, C.M. Prêle and S.E. Mutsaers, Mesothelial cell differentiation into osteoblast- and adipocyte-like cells, Journal of Cellular and Molecular Medicine, 15(10): 2095-2105, 2011.

79. E. Ang, Q. Liu, M. Qi, H.G. Liu, X. Yang, H. Chen, M.H. Zheng and J. Xu, Mangiferin attenuates osteoclastogenesis, bone resorption, and RANKL-induced activation of NF-ΚB and ERK, Journal of Cellular Biochemistry, 112(1): 89-97, 2011.

80. C. Kong and Y-K. Leong, On the Flocculation and Agglomeration of Ceria Dispersion, Journal of Dispersion Science and Technology, 32(9): 1235-1238, 2011.

81. O. Pedersen, C. Pulido, S.M. Rich and T.D. Colmer, In situ O2 dynamics in submerged Isoetes australia: varied leaf gas permeability influences underwater photosynthesis and internal O2, Journal of Experimental Botany, 62(13): 4691-4700, 2011.


103. S.Y. Yeung, S. Kampmann, K.A. Stubbs, B.W. Skelton, B.J. Kaskow, L.J. Abraham and S.G. Stewart, Novel thalidomide analogues with potent NFkB and TNF expression inhibition, MedChemComm, 2: 1073-1078, 2011.

104. R.E. Halse, K.E. Wallman and K.J. Guelfi, Postexercise water immersion increases short-term food intake in trained men, Medicine and Science in Sports and Exercise, 42(4): 632-8, 2011.

105. L.E. Wedlock, M.R. Kilburn, J.B. Cliff, L. Filgueira, M. Saunders and S.J. Berners-Price, Visualizing Gold Inside Tumor Cells Following Treatment with an Antitumor Gold(I) Complex, Metallomics, 3(9): 917-925, 2011.

106. D.C. Joy and B.J. Griffin, Is microanalysis possible in the helium ion microscope?, Microscopy and Microanalysis, 17 (4): 643-649, 2011.

107. M. Saunders, C. Kong, J.A. Shaw and P.L. Clode, Matrix-mediated biomineralization in marine mollusks: A combined transmission electron microscopy and focused ion beam approach, Microscopy and Microanalysis, 17(2): 220-225, 2011.

108. S. Sarma, I.R. Fletcher, B. Rasmussen, N.J. McNaughton, M.R. Mohan and D.I. Groves, Archaean gold mineralization synchronous with late cratonization of the Western Dharwar Craton, India: 2.52 Ga U–Pb ages of hydrothermal monazite and xenotime in gold deposits, Miner Deposita, 46: 273-288, 2011.

109. N.J. Pavlos, T.S. Cheng, A. Qin, P.Y. Ng, H.T. Feng, E.S.M. Ang, A. Carreloo, C.H. Sung, R. Jah, M.H. Zheng and J. Xu, TCTEX-1, A Novel Interaction partner of Rab3D is required for osteoclastic bone resorption, Molecular and Cellular Biology, 31(7): 1551-1564, 2011.

110. L.V. Blomster, J. Vukovic, D.A.E. Hendrickx, S. Jung, A.R. Harvey, L. Filgueira and M.J. Ruitenberg, CX3CR1 deficiency exacerbates neuronal loss and impairs early regenerative responses in the target-ablated olfactory epithelium, Molecular and Cellular Neuroscience, 48: 236-245, 2011.

111. M. Hellstrom, J. Muhling, E.M. Ehlert, J. Verhaaagen, M.A. Pollett, Y. Hu and A.R. Harvey, Negative impact of rAAV2 mediated expression of SOCS3 on the regeneration of adult retinal ganglion cell axons, Molecular and Cellular Neuroscience, 46: 507-515, 2011.

112. D. Ho, M. Fitzgerald, C.A. Bartlett, B. Zdyrko, I.A. Luzinov, S.A. Dunlop and K. Swaminathan Iyer, The effects of concentration-dependent morphology of self-assembling RADA16 nanoscaffolds on mixed retinal cultures, Nanoscale, 3: 907-910, 2011.

113. T.D. Clemons, C.W. Evans, B. Zdyrko, I. Luzinov, M. Fitzgerald, S.A. Dunlop, A.R. Harvey, K. Swaminathan Iyer and K.A Stubbs, Multifunctional nanoadditives for the thermodynamic and kinetic stabilization of enzymes, Nanoscale, 3: 4085-4087, 2011.

114. M.R.J. Carrol, P.P. Huffstetler, W.C. Miles, J.D. Goff, R.M. Davis, J.S. Riffle, M.J. House, R.C. Woodward and T.G. St Pierre, The effect of polymer coatings on proton transverse relaxivities of aqueous suspensions of magnetic nanoparticles, Nanotechnology, 22: 325702 (7pp), 2011.

115. D. Wacey, M.R. Kilburn, M. Saunders, J. Cliff and M.D. Brasier, Microfossils of sulphur-metabolizing cells in 3.4-billion-year-old rocks of Western Australia, Nature Geoscience, 4: 698-702, 2011.

116. M. Werner and L.W. Simmons, Ultrastructure of spermatozoa of Onthophagus taurus (Coleoptera, Scarabaeidae) exhibits heritable variation, Naturwissenschaften, 98(3): 213-223, 2011.

117. C. Balaratnasingam, W.H. Morgan, L. Bass, M. Kang, S.J. Cringle, D.Y. Yu, Axotomy-induced cytoskeleton changes in unmyelinated mammalian central nervous system axons, Neuroscience, 177: 269-282, 2011.

118. J. Zou, K. Swaminathan Iyer, S.G. Stewart and C.L. Raston, Scalable synthesis of catalysts for the Mizoroki–Heck cross coupling reaction: palladium nanoparticles assembled in a polymeric nanospherew, New Journal of Chemistry, 35: 854-860, 2011.

119. N.L. Teakle, J. Armstrong, E.G. Barrett-Lennard and T.D. Colmer, Aerenchymatous phellem in hypocotyl and roots enables O2 transport in Melilotus siculus, New Phytologist, 190: 340-350, 2011.

120. S.M. Rich, M. Ludwig, O. Pedersen and T.D Colmer, Aquatic adventitious roots of the wetland plant Meinoectes brownii can photosynthesize: implications for root function during flooding, New Phytologist, 190: 311-319, 2011.

121. A. Curatolo, B. F. Kennedy, D. D. Sampson, Structured three-dimensional optical phantoms for optical coherence tomography, Optics Express, 19(20): 19480-1948, 2011.

122. B.F. Kennedy, X. Liang, S.G Adie, D.K. Gerstmann, B.C. Quirk, S.A. Boppart, D.D. Sampson, In vivo three-dimensional optical coherence elastography, Optics Express, 19(7): 6623-6634, 2011.

123. R.S. Pillai, D. Lorenser, D.D. Sampson, Deep-tissue access with confocal fluorescence microendoscopy through hypodermic needles, Optics Express, 19(8): 7213-7221, 2011.

124. D. Lorenser, X. Yang, R.W. Kirk, B.C. Quirk, R.A. McLaughlin, D.D. Sampson, Ultra-thin side-viewing needle probe for optical coherence tomography, Optics Letters, 36(19): 3894-3896, 2011.

125. R.M. Hough, R.R.P. Noble and M. Reich, Natural gold nanoparticles, Ore Geology Reviews, 42: 55-61, 2011.

126. D.J. Armitt, M.I. Bruce, J.C. Morris, B.K. Nicholson, C.R. Parker, B.W. Skelton and N.N. Zaitseva, Bis(metallaethynyl) ketones: synthesis and structure of {(Ph3P) Au-CΚC}2CO and attempted transmetalation: formation and structure of [1,3-{Ru(dppe)Cp}2{c-COC(OMe)CHCCH}]PF6, Organometallics, 30: 5452-5456, 2011.

127. D D. Sampson, Staying coherent after Kent: From optical communications to biomedical optics, Photonic Sensors, 1(4): 323-350, 2011.

128. M. Lai, G. Parish, J. Dell, Y. Liu and A. Keating, Chemical resistance of porous silicon: Photolithographic applications, Physica Status Solidi (c), 8(6): 1847-1850, 2011.

129. H.J. Clarke, M. Kumari, T.N. Khan and K.H.M Siddique, Poorly formed chloroplasts are barriers to successful interspecific hybridization in chickpea following in vitro embro rescue, Plant Cell, Tissue and Organ Culture, 106: 465-473, 2011.

130. J. Takahira, A.Cousin, M.N. Nelson and W.A. Cowling, Improvement in efficiency of microspore culture to produce doubled haploid canola (Brassica napus L.) by flow cytometry, Plant Cell, Tissue and Organ Culture, 104: 51-59, 2011.

131. S. Shabala, L. Bækgaard, L. Shabala, A. Fuglsang, O. Babourina, M.G. Palmgren, T.A. Cuin, Z. Rengel and L.G. Nemchinov, Plasma membrane Ca2+ transporters mediate virus-induced acquired resistance to oxidative stress, Plant, Cell and Environment, 34(3): 406-417, 2011.

132. A. Qin, T.S. Cheng, Z. Lin, N.J. Pavlos, Q. Jiang, J. Xu, K.R. Dai and M.H. Zheng, Versatile roles of V-ATPases accessory subunit Ac45 in osteoclast formation and function, PLoS One, 6(11): e27155, 2011.

133. G. Ravenscroft, C. Jackaman, C.A. Sewry, E. McNamara, S.E. Squire, A.C. Potter, J. Papadimitriou, L.M. Griffiths, A.J. Bakker, k.E. Davies, N.G. Laing, K.J. Nowak, Actin nemaline myopathy mouse reproduces disease, suggests other actin disease phenotypes and provides cautionary note on muscle transgene expression, PLoS One, 6(12): e28699, 2011.


134. A. Chew, P. Salama, A. Robbshaw, B. Klopcic, N. Zeps, C. Platell and I.C. Lawrance, SPARC, FOXP3, CD8 and CD45 correlation with disease recurrence and long-term disease-free survival in colorectal cancer, PLoS One, 6(7): e22047, 2011.

135. R.J. Chai, J. Vukovic, S. Dunlop, M.D. Grounds and T. Shavlakadze, Striking Denervation of Neuromuscular Junctions without Lumbar Motoneuron Loss in Geriatric Mouse Muscle, PLoS One, 6(12): e28090, 2011.

136. E-J. Teh, Y.-K. Leong and Y. Liu, The effect of adsorbed fumaric acid on dispersions of rough titania particles, Powder Technology, 223: 110-115, 2011.

137. S.P. Johnson, S. Sheppard, B. Rasmussen, M.T.D. Wingate, C.L. Kirkland, J.R. Muhling, I.R. Fletcher and E.A. Belousova, Two collisions, two sutures: punctuated pre-1950 Ma assembly of the West Australian Craton during the Ophthalmian and Glenburgh Orogenies, Precambrian Research, 189: 239-262, 2011.

138. T.S. Blake, E. Rothery, J.R. Muhling, J.A.P. Drake-Brockman, L.C. Sprigg, S.E. Ho, B. Rasmussen and I.R. Fletcher, Two episodes of regional-scale Precambrian hydrothermal alteration in the eastern Pilbara, Western Australia, Precambrian Research, 188: 73-103, 2011.

139. D.M. Collinson, K.M. Usher, P.D. Nichols and H.R. Watling, Habituation of Sulfobacillus thermosulfidooxidans to 4-nonylphenol in ferrous ion growth medium, Process Biochemistry, 46: 108-115, 2011.

140. B.J. Griffin, A Comparison of Conventional Everhart-Thornley Style and In-Lens Secondary Electron Detectors—A Further Variable in Scanning Electron Microscopy, Scanning, 33: 162-173, 2011.

141. L. Zhu, G.A. Gaetani, F. Fusseis, L.G.J. Montesi, and F. De Carlo, Microtomography of partially molten rocks: Three-dimensional melt distribution in mantle peridotite, Science, 332: 88-91, 2011.

142. L.C. Zhang, D. Klemm, J. Eckert, Y.L. Hao and T.B. Sercombe, Manufacture by selective laser melting and mechanical behavior of a biomedical Ti-24Nb-4Zr-8Sn alloy, Scripta Materialia, 65: 21-24, 2011.

143. Q. Meng, Y. Liu, H. Yang and T. Nam, Laser annealing of functionally graded NiTi thin plate, Scripta Materialia, 65: 1109-1112, 2011.

144. M. Myers, J. Cooper, B. Pejcic, M. Baker, B. Raguse and L. Wieczorek, Functionalized graphene as an aqueous phase chemiresistor sensing material, Sensors and Actuators B: Chemical, 155: 154-158, 2011.

145. P.C. Wu, T-H. Kim, A. Suvorova, M. Giangregorio, M. Saunders, G. Bruno, A.S. Brown and M. Losurdo, GaMg Alloy Nanoparticles for Broadly Tunable Plasmonics, Small, 7(6): 751-756, 2011.

146. M. Kocan, F. Recht, G.A. Umana-Membreno, M.R. Kilburn, B.D. Nener, U.K. Mishra and G. Parish, Implantation angle periphery effects on non-alloyed Si-implanted ohmic contacts for AlGaN/GaN high electron mobility transistors, Solid State Electronics, 56: 56-59, 2011.

147. S.G. Kallapur, B.W. Kramer, C.L. Know, C.A. Berry, J.J.P. Collins, M.W. Kemp, I. Nitsos, G.R. Polglase, J. Robinson, N.H. Hillman, J.P. Newnham, C. Chougne, and A.H.Jobe, Chronic fetal exposure to Ureaplasma parvum suppresses innate immune responses in sheep, The Journal of Immunology, 187(5): 2688-2695, 2011.

148. V.S. Fear, J.T. Burchell, S.P. Lai, M.E. Wikstrom, F. Blank, C. Von Garnier, D.J. Turner, P.D. Sly, P.G. Holt, D.S. Strickland and P.A. Stumbles, Restricted aeroallergen access to airway mucosal dendritic cells in vivo limits allergen-specific CD4+ T cell proliferation during the induction of inhalation tolerance, The Journal of Immunology, 187: 4561-4570, 2011.

149. J. Chen, Q. Yu, B. Wu, Z. Lin, N.J. Pavlos, I. Xu, H. Ouyang, A. Wang and M.-H.Zheng, Autologous tenocyte therapy for experimental achilles tendinopathy in a rabbit model, Tissue Engineering: Part A, 17(15-16): 2037-2048, 2011.

150. M.G. Thomas, L. Stone, L. Evill, S. Ong, M. Ziman and L. Hool, Bone marrow stromal cells as replacement cells for Parkinson’s disease: generation of an anatomical but not functional neuronal phenotype, Translational Research, 157(2): 56-63, 2011.

151. R.K. Brundavanam, Z-T. Jiang, P. Chapman, X-T. Le, N. Mondinos, D. Fawcett and G.E.J. Poinern, Effect of dilute gelatine on the ultrasonic thermally assisted synthesis of nano hydroxyapatite, Ultrasonics Sonochemistry, 18: 697-703, 2011.

152. M. Salasi, G.B. Stachowiak and G.W. Stackowiak, Three-body tribocorrosion of high-chromium cast irons in neutral and alkaline environments, Wear, 271: 1385-1396, 2011.

2012Book Chapters

1. D. Wacey, In situ, high spatial resolution techniques in the search for the origin of life, In: Seckbach, J. (Ed.) Genesis – In the Beginning. Precursors of Life, Chemical Models and Early Biological Evolution. Cellular Origin, Life in Extreme Habitats and Astrobiology v22, (804 pages), Part 2: 391-411, 2012.

2. J. Cliff, Elemental Signatures for Microbial Forensics, In: Cliff, J.B., Kreuzer, H.W., Ehrhyardt, C.J. and Wunschel, D.S. (Eds.) Chemical and Physical Signatures for Microbial Forensics, (138 pages), Chapter 6: 71-88, 2012.

3. L.R. Brooker and J. Shaw, Chiton Radula: A Unique Model for Biomineralisation Studies, In: Seto, J. Advanced Topics in Biomineralization, (164 pages), Chapter 4: 65-84, 2012.

4. M. Stat, A.C. Baker, D.G. Baker, D.G. Bourne, A.M.S. Correa, Z. Forsman, M.J. Huggett, X. Pochon, D. Skillings, R.J. Toonen, M.J.H. van Oppen and R.D. Gates, Molecular delineation of species in the coral holobiont, In: Lesser, M.P. (Ed.) Advances in Marine Biology, v63 (253 pages), Chapter 1: 1-46, 2012.

Journal Publications1. T. Alam, P.J. Felfera, M. Chaturvedi,

L.T. Stephenson, M.R. Kilburn and J.M. Cairney, Segregation of B, P and C in the Ni-based superalloy, Inconel 718, Metallurgical and Materials Transactions A, 43: 2183-2191, 2012.

2. T. Angerer, S.G. Hagemann and L.V. Danyushevsky, Geochemical Evolution of the Banded Iron Formation-Hosted High-Grade Iron Ore System in the Koolyanobbing Greenstone Belt, Western Australia, Economic Geology, 107: 599-644, 2012.

3. E.S.M. Ang, N.J. Pavlos, S.M. Chim, H.T. Feng, R.M. Scaife, J.H. Steer, M.H. Zheng and J. Xu, Paclitaxel Inhibits Osteoclast Formation and Bone Resorption Via Influencing Mitotic Cell Cycle Arrest and RANKL-Induced Activation of NF-kB and ERK, Journal of Cellular Biochemistry: 113, 946-955, 2012.

4. A. Arulpragasam, A.L. Magno, E. Ingley, S.J. Brown, A.D. Conigrave, T. Ratajczak and B.K. Ward, The adaptor protein 14-3-3 binds to the calcium-sensing receptor and attenuates receptor-mediated Rho kinase signalling, Biochemical Journal, 441: 995-1006, 2012.


13. M. D. Brown, R. van der Most, J.B. Vivian, R.A. Lake, I. Larma, B.W. Robinson and A.J. Currie, Loss of antigen cross-presentation after complete tumor resection is associated with the generation of protective tumor-specific CD8(+) T-cell immunity, OncoImmunology, 1:1(7): 1084-1094, 2012.

14. M.I. Bruce, A. Burgun, G. Grelaud, C. Lapinte, B.W. Skelton and N.N. Zaitseva, Reactions of 7,7,8,8-Tetracyanoquinodimethane (TCNQ) with Alkynyl-Iron- and -Ruthenium Complexes: Synthesis of Ru{CΚCC(CN)=C6H4=C(CN)2}(PPh3)2Cp, a New Donor-Acceptor Molecular Array, Australian Journal of Chemistry, 65: 763-772, 2012.

15. M.I. Bruce, N.N. Zaitseva, B.W. Skelton, Reactions of Ru(CΚCPh)(PPh3)2Cp with silver(I): Molecular structure of [Ag{h2-PhC2[Ru(PPh3)2Cp]}2]PF6 and synthesis of a bis(vinylidene) complex, Journal of Organometallic Chemistry, 716: 281-284, 2012.

16. M.I. Bruce, A. Burgun, B.K. Nicholson, C.R. Parker, B.W. Skelton and A.H. White, Polarized complexes obtained by regiospecific substitution of a CN group in Ru{CCC(CN)=C(CN)2}(dppe)Cp* (Cp* = -C5Me5), Organometallics, 31: 4174-4181, 2012.

17. M.I. Bruce, A. Burgun, G. Grelaud, C. Lapinte, C.R. Parker, T. Roisnel, B.W. Skelton and N.N. Zaitseva, Reactions of 7,7,8,8-Tetracyanoquinodimethane with poly-ynyl ruthenium and iron complexes, Organometallics, 31: 6623-6634, 2012.

18. M.I. Bruce, B.W. Skelton and N.N. Zaitseva, A Ruthenated [3]Dendralene from Phenylethyne and an n3-Butadienyl−Ruthenium Complex, Organometallics, 31: 5034-5038, 2012.

19. M.I. Bruce, M.A. Fox, P.J. Low, B.K. Nicholson, C.R. Parker, W.C. Patalinghug, B.W. Skelton and A.H. White, Substitution of tetracyanoethene by ethynyl−metal complexes gives tricyanovinylethynyl (Tricyanobutenynyl) derivatives: syntheses, protonation, and addition of metal−ligand fragments, Organometallics, 31: 2639-2657, 2012.


5. J.-P. Bacik, G.E. Whitworth, K.A. Stubbs, D.J. Vocadlo and B.L. Mark , Active site plasticity within the glycoside hydrolase NagZ underlies a dynamic mechanism of substrate distortion, Chemistry and Biology, 19(11): 1471-1482, 2012.

6. K.A. Bates, V.W. Clark, B.P. Meloni, S.A. Dunlop and J. Rodger, Short-term low intensity PMF does not improve functional or histological outcomes in a rat model of transient focal cerebral ischemia, Brain Research, 1458: 76-85, 2012.

7. R.J. Betts, T.S. Mann and P.J. Henry, Inhibitory influence of the hexapeptidic sequence SLIGRL on influenza A virus infection in mice, The Journal of Pharmacology and Experimental Therapeutics, 343: 725-735, 2012.

8. B. Bohman, l. Jeffares, G. Flematti, L.T. Byrne, B.W. Skelton, R.D. Phillips, K.W. Dixon, R. Peakall and R.A. Barrow, Discovery of tetrasubstituted pyrazines as semiochemicals in a sexually deceptive orchid, Journal of Natural Products, 75(9): 1589-1594, 2012.

9. B. Bohman, L. Jeffares, G. Flematti, R.D. Phillips, K.W. Dixon, R. Peakall and R.A. Barrow, The discovery of 2-Hydroxymethyl-3-(3-methylbutyl)-5-methylpyrazine: A semiochemical in orchid pollination, Organic Letters, 14: 2576-2578, 2012.

10. J.H. Bowie, M.I. Bruce, M.A. Buntine, A.S. Gentleman, D.C. Graham, P.J. Low, G.F. Metha, C. Mitchell, C.R. Parker, B.W. Skelton and A.H. White, Facile decarboxylation of propiolic acid on a ruthenium center and related chemistry, Organometallics, 31: 5262-5273, 2012.

11. G.A. Bowmaker, J.V. Hanna, R.D. Hart, P.C. Healy, S.P. King, F. Marchetti, C. Pettinari, B.W. Skelton, A. Tabacaruf and A.H. Whitec, Mechanochemical and solution synthesis, X-ray structure and IR and 31P solid state NMR spectroscopic studies of copper(I) thiocyanate adducts with bulky monodentate tertiary phosphine ligands, Dalton Transactions, 41: 7513-7525, 2012.

12. M.D. Brasier and D. Wacey, Fossils and astrobiology: new protocols for cell evolution in deep time, International Journal of Astrobiology, 11(4): 217-228, 2012.

20. E.A. Buvaylo, V.N. Kokozay, O.Yu. Vassilyeva and B.W. Skelton, [2-(Dimethylamino)ethanol-k2N,O][2-(dimethylamino)-ethanolatok2N,O]iodidocopper(II), Acta Crystallographic Section E, E68: m419-m420, 2012.

21. O.V. Kozachuk, V.N. Kokozay, O.Y. Vassilyeva and B.W. Skelton, Bis[(cyanido- C)bis(1,10-phenanthroline- 2N,N)copper(II)] pentakis(cyanido- C)nitrosoferrate(II) dimethylformamide monosolvate, Acta Crystallographic Section E, E68: m1218-m1219, 2012.

22. E.A. Buvaylo, O.V. Nesterova, V.N. Kokozay, O.Yu. Vassilyeva, B.W. Skelton, R. BocΚa and D.S. Nesterov, Discussion of planarity of molecular structures using novel pentanuclear Cu/Ni complexes as an example, Crystal Growth and Design, 12: 3200-3208, 2012.

23. B.C.Y. Chan, X. Wang, L.K.W. Lam, J.M. Gordon, D. Feuermann, C.L. Raston and H.T. Chua, Light-driven high-temperature continuous-flow synthesis of TiO2 nano-anatase, Chemical Engineering Journal, 211-212: 195-199, 2012.

24. J.C. Clements, J. Wilson, M.W. Sweetingham, J. Quealy and G. Francis, Male sterility in three crop Lupinus species, Plant Breeding, 131(1): 155-163, 2012.

25. X.Chen, R.A. Boulos, P.K. Eggers and C.L. Raston, p-Phosphonic acid calix[8]arene assisted exfoliation and 2D materials in waterstabilization of, Chemical Communications, 48: 11407-11409, 2012.

26. X. Chen, J.F. Dobson and C.L Raston, Vortex fluidic exfoliation of graphite and boron nitride, Chemical Communications, 48(31): 3703-3705, 2012.

27. C.J. Chernicoff, E.O. Zappettini, J.O.S. Santos, M.C. Godeas, E. Belousova and N.J. McNaughton, Identification and isotopic studies of early Cambrian magmatism (El Carancho Igneous Complex) at the boundary between Pampia terrane and the Río de la Plata craton, La Pampa province, Argentina, Gondwana Research, 21: 378-393, 2012.

28. H.R. Chinnery, S. McLenachan, N. Binz, Y. Sun, J.V. Forrester, M.A. Degli-Esposti, E. Pearlman and P.G. McMenamin, TLR9 Ligand CpG-ODN Applied to the Injured Mouse Cornea Elicits Retinal Inflammation, American Journal of Pathology, 180(1): 209-220, 2012.

29. H.R. Chinnery, S. McLenachan, T. Humphries, J.M. Kezic, X. Chen, M.J. Ruitenberg and P.G. McMenamin, Accumulation of murine subretinal macrophages: effects of age, pigmentation and CX3CR1, Neurobiology of Aging, 33(8): 1769-1776, 2012.

2012 Journal Papers

Total 152

Biological/biomedical sciences 100

Physical sciences 63

Environmental/geosciences 40


30. P.A. Christin, M.J. Wallace, H. Clayton, E.J. Edwards, R.T. Furbank, P.W. Hattersley, R.F. Sage, T.D. MacFarlane and M. Ludwig, Multiple photosynthetic transitions, polyploidy, and lateral gene transfer in the grass subtribe Neurachninae, Journal of Experimental Botany, 63(17): 6267-6308, 2012.

31. J.E. Collins, S.J. Barnes, S.G. Hagemann, T.C. McCuaig and K.M. Frost, Postmagmatic Variability in ore composition and mineralogy in the T4 and T5 ore shoots at the high-grade Flying Fox Ni-Cu-PGE Deposit, Yilgarn Craton, Western Australia, Economic Geology, 107: 859–879, 2012.

32. A. Curatolo, R.A. McLaughlin, B.C. Quirk, R.W. Kirk, A.G. Bourke, B.A. Wood, P. Robbins, C.M. Saunders and D.D. Sampson, Ultrasound-guided optical coherence tomography needle probe for the assessment of breast cancer tumor margins, American Journal of Roentgenology, 199(4): 520-522, 2012.

33. D. D’Alessio, L.E. Karagiannidis, B.W. Skelton, M. Massi and M.I. Ogden, Hydrated lanthanoid complexes of 5-(2’-Pyridyl)tetrazole formed in the presence of Dimethyl Sulfoxide*, Australian Journal of Chemistry, 65: 819-822, 2012.

34. D.D. D’Alessio, S. Muzzzioli, B.W. Skelton, S. Stagni, M. Massi and M.I. Ogden, Luminescent lanthanoid complexes of a tetrazole-functionalised calix[4]arene, Dalton Transactions, 41: 4736-4739, 2012.

35. T. Darunsontaya, A. Suddhiprakarn, I. Kheoruenromne, N. Prakongkep and R.J. Gilkes, The forms and availability to plants of soil potassium as related to mineralogy for upland Oxisols and Ultisols from Thailand, Geoderma, 170: 11-24, 2012.

36. D. De Santis, B. Foley, C.S. Witt and F.T. Christiansen, The detection of NK cell alloreactivity by flow cytometric CD107a assay, Methods in Molecular Biology, 882: 477-489, 2012.

37. A.W. Debowski , C. Carnoy, P. Verbrugghe, H.O. Nilsson, J.C. Gauntlett, A. Fulurija, T. Camilleri, D.E. Berg, B.J. Marshall and M. Benghezal, Xer recombinase and genome integrity in Helicobacter pylori, a pathogen without topoisomerase IV, PLoS ONE, 7(4): e33310, 2012.

38. R.D. Delima, A.C. Chua, J.E. Tirnitz-Parker, E.K. Gan, K.D. Croft, R.M. Graham, J.K. Olynyk and D. Trinder, Disruption of hemochromatosis protein and transferrin receptor 2 causes iron-induced liver injury in mice, Hepatology, 56(2): 585-93, 2012.

39. S. Dev, P. Prabhakaran, L. Filgueira, K.S. Iyer and C.L. Raston, Microfluidic fabrication of cationic curcumin nanoparticles as an anti-cancer agent, Nanoscale, 4(8): 2575-2579, 2012.

40. E.S. Drummond, R.N. Martins, D.J. Handelsman and A.R. Harvey, Altered expression of alzheimers disease relation proteins in male hypogonadal mice, Neuroendocrinology, 153(6): 2789-2799, 2012.

41. X. Du, A.W. Rate and M.A.M. Gee, Redistribution and mobilization of titanium, zirconium and thorium in an intenselyweathered lateritic profile in Western Australia, Chemical Geology, 330-331: 101-115, 2012.

42. D’Vaz N, Meldrum SJ, Dunstan JA, Lee-Pullen TF, Metcalfe J, Holt BJ, et al. 16. , Fish oil supplementation in early infancy modulates developing infant immune responses, Clinical and Experimental Allergy, 42(8): 1206-1216, 2012.

43. N. D’Vaz, Y. Ma, J.A. Dunstan, T.F. Lee-Pullen, C. Hii, S. Meldrum, G. Zhang, J. Metcalfe, A. Ferrante and S.L. Prescott, Neonatal protein kinase C zeta expression determines the neonatal T-Cell cytokine phenotype and predicts the development and severity of infant allergic disease, Allergy: European Journal of Allergy and Clinical Immunology, 67(12): 1511-1518, 2012.

44. L.G. Dyer, K.W. Chapman, P. English, M. Saunders and W.R. Richmond, Insights into the crystal and aggregate structure of Fe3+ oxide/silica co-precipitates, American Mineralogist, 97: 63-69, 2012.

45. H. Edwards, R.C.A. Thompson, W.H. Koh and P.L. Clode, Labeling surface epitopes to identify Cryptosporidium life stages using a scanning electron microscopy-based immunogold approach, Molecular and Cellular Probes, 26: 21-28, 2012.

46. P.K. Eggers, T. Becker, M.K. Melvin, R.A. Boulos, E. James, N. Morellini, A.R. Harvey, S.A. Dunlop, M. Fitzgerald, K.A. Stubbs and C.L. Raston, Composite fluorescent vesicles based on ionic and cationic ampiphilic calix[4]arenes, RSC Advances, 2(15): 6250-6257, 2012.

47. E. Eroglu, V. Agarwal, M. Bradshaw, X. Chen, S.M. Smith, C.L. Raston and K.S. Iyer, Nitrate removal from liquid effluents using microalgae immobilized on chitosan nanofiber mats, Green Chemistry, 14(10): 2682-2685, 2012.

48. S. Etemad, R.M. Zamin, M.J. Ruitenberg and L. Filgueira, A novel in vitro human microglia model: characterization of human monocyte-derived microglia, Journal of Neuroscience Methods, 30; 209(1): 79-89, 2012.

49. C. Evans, M.J. Latter, D. Ho, S.A.M.A. Peerzade, T.D. Clemons, M. Fitzgerald, S.A. Dunlop and K.S. Iyer, Multimodal and multifunctional stealth polymer nanospheres for sustained drug delivery, New Journal of Chemistry, 36: 1457-1462, 2012.

50. N.S. Fabina, H.M. Putnam, E.C. Franklin, M. Stat and R.D. Gates, Transmission mode predicts specificity and interaction patterns in coral-Symbiodinium networks, PLoS ONE, 7(9): e44970., 2012.

51. A.S. Fogliata, M.A. Baez, S.G. Hagemann, J.O. Santos and F. Sardi, Post-orogenic, Carboniferous granite-hosted Sn–W mineralization in the Sierras Pampeanas Orogen, Northwestern Argentina, Ore Geology Reviews, 45: 16-32, 2012.

52. B. Fu, B. Paul, J. Cliff, M. Brooker and F. Bulle, O-Hf isotope constraints on the origin of zircon in high-pressure melange blocks and associated matrix rocks from Tinos and Syros, Greece, European Journal of Mineralogy, 24: 277-287, 2012.

53. M. Gagliano, M. Renton, N. Duvdevani, M. Timmins and S. Mancuso, Out of sight but not out of mind: Alternative means of communication in plants, PLoS ONE, 7(5): e37382, 2012.

54. M. Gagliano, M. Renton, N. Duvdevani, M. Timms and S. Mancuso, Acoustic and magnetic communication in plants Is it possible?, Plant Signaling & Behaviour, 7(10): 1-3, 2012.

55. M. Gagliano, S. Mancuso and D. Robert, Towards understanding plant bioacoustics, Trends in Plant Science, 17(6): 323-25, 2012.

56. M.M. Giangregorio, G.V. Bianco, P. Capezzuto, G. Bruno, M.Losurdo, A.A. Suvorova and M. Saunders, Optical properties of silicon semiconductor-supported gold nanoparticles and nanopolyedrons obtained by sputtering, Journal of Nanoscience and Nanotechnology, 12: 8224-8229, 2012.

57. S. Grabowdky, P.M. Dean, B.W. Skelton, A.N. Sobolev, M.A. Spackman and A.H. White, Crystal packing in the 2-R,4-oxo-[1,3-a/b]-naphthodioxanes – Hirshfeld surface analysis and melting point correlation, CrystEngComm, 14: 1083-1093, 2012.

58. C.S. Griffith and G.A.Koutsantonis, The chemistry of transition metal ethyne-1,2-diyl complexes, Australian Journal of Chemistry, 65: 7, 2012.

59. K.J. Guelfi, C.E. Donges and R. Duffield, Beneficial effects of 12 weeks of aerobic compared with resistance exercise training on perceived appetite in previously sedentary overweight and obese men, Metabolism: Clinical and Experimental, 62(2): 235-243, 2012.


60. B.S. Gully, J. Zou, G. Cadby, D.M. Passon, K. Swaminathan Iyer and C.S. Bond, Colloidal graphenes as heterogeneous additives to enhance protein crystal yield, Nanoscale, 4(17): 5321-5324, 2012.

61. C. Jackaman and D.J. Nelson, Intratumoral interleukin-2/agonist CD40 antibody drives CD4 +-independent resolution of treated-tumors and CD4 +-dependent systemic and memory responses, Cancer, Immunology, Immunotherapy, 61(4): 549-60, 2012.

62. D.W. Hait and E. McCartain, Intraspecific variation in Triassic Ophthalmidiid Foraminifera from Timor, Revue de micropaleontologie, 55: 39-52, 2012.

63. K.A. Hammer and K.A. Heel, Use of multiparameter flow cytometry to determine the effects of monoterpenoids and phenylpropanoids on membrane polarity and permeability in staphylococci and enterococci, International Journal of Antimicrobial Agents, 40: 239-245, 2012.

64. J. Harrison, C.A Bartlett, G. Cowin, P.K. Nicholls, C.W. Evans, T.D. Clemons, B. Zdyrko, I.A. Luzinov, A.R. Harvey, K. Swaminathan Iyer, S.A. Dunlop and M. Fitzgerald, In vivo Imaging and biodistribution of multimodal polymeric nanoparticles delivered to the optic nerve, Small, 8(10): 1579-1589, 2012.

65. F. Hassiotou, A. Beltran, E. Chetwynd, A.M. Stuebe, A.J. Twigger, P. Metzger, N. Trengove, C.T. Lai, L. Filgueira, P. Blancafort and P.E. Hartmann, Breastmilk is a novel source of stem cells with multilineage differentiation potential., Stem Cells, 30(10): 2164-74, 2012.

66. M. Hattie, A.W. Debowski and K.A. Stubbs, Development of Tools to Study Lacto-N-Biosidase: An Important Enzyme Involved in the Breakdown of Human Milk Oligosaccharides, ChemBioChem, 13(8): 1128-1131, 2012.

67. H. He, T.M. Bleby, E.J. Vencklaas, H. Lambers and J. Kuo, Morphologies and elemental compositions of calcium crystals in and branchlets of Acacia robeorum (Leguminosae: Mimosoideae) phyllodes, Annals of Botany, 109: 887-896, 2012.

68. H. He, T.M. Bleby, E.J. Veneklaas, H. Lambers and J. Kuo, Precipitation of calcium, magnesium, strontium and barium in tissues of four acacia species (leguminosae: Mimosoideae), PLoS ONE, 7(7): e41563, 2012.

69. J.N. Herwig, M. Depczynski, J.D. Roberts, J.M. Semmens, M. Gagliano and A.J. Heyward, Using Age-Based Life History Data to Investigate the Life Cycle and Vulnerability of Octopus cyanea, PLoS ONE, 7(8): e43679, 2012.

70. N. Hondow, J. Harrowfield, G. Koutsantonis, G. Nealon and M. Saunders, Metallosurfactants in the preparation of mesoporous silicas, Microporous and Mesoporous Materials, 151: 264-270, 2012.

71. H. Husin, Y-K. Leong and J. Liu, The effects of benzoic acid compounds in -Al2O3 dispersions: Additional attractive forces of particle bridging and precipitate bridging, Colloids and Surfaces A: Physicochemical and Engineering Aspects, 402: 159-167, 2012.

72. P.G. Hutton, Z. Durmic, E.L. Ghisalberti, G. R. Flematti, R.M. Duncan, C.F. Carson, T.V. Riley and P.E. Vercoe, Inhibition of ruminal bacteria involved in lactic acid metabolism by extracts from Australian plants, Animal Feed Science Technology, 176: 170-177, 2012.

73. D.J. Ireland, H.T. Kissick and M.W. Beilharz, The Role of Regulatory T Cells in Mesothelioma, Cancer Microenvironment, 5: 165-172, 2012.

74. D.J. Ireland, S.J. Greay, C.M. Hooper, H.T. Kissick, P. Filion, T.V. Riley and M.W. Beilharz, Topically applied Melaleuca alternifolia (tea tree) oil causes direct anti-cancer cytotoxicity in subcutaneous tumour bearing mice, J Dermatol Sci, 67(2): 120-9, 2012.

75. C. Jackaman, S. Lansley, J.E. Allan, B.W. Robinson and D.J. Nelson, IL-2/CD40-driven NK cells install and maintain potency in the anti-mesothelioma effector/memory phase, International Immunology, 24(6): 357-68, 2012.

76. F. Jiang, Y.K. Leong, M. Saunders, M. Martyniuk, L. Faraone, A. Keating and J.M. Dell, Uniform Dispersion of Lanthanum Hexaboride Nanoparticles in a Silica Thin Film: Synthesis and Optical Properties, ACS Applied Materials and Interfaces, 4(11): 5833-5838, 2012.

77. F. Jiang, A. Keating, M. Martyniuk, K. Prasad, L. Faraone and J.M. Dell, Characterization of low-temperature bulk micromachining of silicon using an SF6/O2 inductively coupled plasma, Journal of Micromechanics and Microengineering, 22(9): art. No 095005, 2012.

78. J.M. Kabete, M.J. McNaughton, D.I. Groves and A.H. Mruma, Reconnaissance SHRIMP U–Pb zircon geochronology of the Tanzania Craton: Evidence for Neoarchean granitoid–greenstone belts in the Central Tanzania Region and the Southern East African Orogen, Precambrian Research, 216-219: 232-266, 2012.

79. P.J. Kelly, K.J. Guelfi, K.E. Wallman and T.J. Fairchild, Mild dehydration does not reduce postexercise appetite or energy intake, Medicine & Science in Sports & Exercise, 44(3): 516-524, 2012.

80. B. F. Kennedy, M. Wojtkowski, M. Szkulmowski, K.M. Kennedy, K. Karnowski and D.D. Sampson, Improved measurement of vibration amplitude in dynamic optical coherence elastography, Biomedical Optics Express, 3(12): 3138-3152, 2012.

81. B.F. Kennedy, S.H. Koh, R.A. McLaughlin, K.M. Kennedy, P.R.T. Munro and D.D. Sampson, Strain estimation in phase-sensitive optical coherence elastography, Biomedical Optics Express, 3(8): 1865-1879, 2012.

82. K.M. Kennedy, B.F. Kennedy, R.A. McLaughlin and D.D. Sampson, Needle optical coherence elastography for tissue boundary detection, Optics Letters, 37(12): 2310-2312, 2012.

83. H.T. Kissick, D.J. Ireland, S. Krishnan, M. Madondo and M.W. Beilharz, Tumour eradication and induction of memory against murine mesothelioma by combined immunotherapy, Immunol Cell Biology, 90(8): 822-6, 2012.

84. S. Kwang and P.V. Abbott, Bacterial contamination of the fitting surfaces of restorations in teeth with pulp and periapical disease: a scanning electron microscopy study, Australian Dental Journal, 57(4): 421-428, 2012.

85. M. Lai, G. Parish, Y. Liu and A.J. Keating, Surface Morphology Control of Passivated Porous Silicon Using Reactive Ion Etching, Journal of Microelectromechanical Systems, 21(3): 756-761, 2012.

86. M. Lai, G.M. Sridharan, G. Parish, S. Bhattacharya and A. Keating, Multilayer porous silicon diffraction gratings operating in the infrared, Nanoscale Research Letters, 7: 645-653, 2012.

87 H. Lambers, G.R. Cawthray, P. Giavalisco, J. Kuo, E. Laliberté, S.J. Pearse, W. Scheible, M. Stitt, F. Teste and B. Turner, Proteaceae from severely phosphorus-impoverished soils extensively replace phospholipids with galactolipids and sulfolipids during leaf development to achieve a high photosynthetic phosphorus-use-efficiency, New Phytologist, 196(4): 1098-1108, 2012.

88. G. Lamouche, B.F. Kennedy, K.M. Kennedy, C-E. Bisaillon, A. Curatolo, G. Campbell, V. Pazos and D.D. Sampson, Review of tissue simulating phantoms with controllable optical, mechanical and structural properties for use in optical coherence tomography, Biomedical Optics Express, 3(6): 1381-1398, 2012.

89. Z-W. Lan and Z-Q. Chen, New xenotime ages obtained from the Paleoproterozoic Kimberley Group, NW Australia: implications for regional hydrothermal events, Australian Journal of Earth Sciences; An International Geoscience Journal of the Geological Society of Australia, 59(1): 119-133, 2012.


90. Z-W. Lan and Z-Q. Chen, Scanning electron microscopic imaging and nano-secondary ion microprobe analyses of bacteria-like nanoball structures in oncoids from the Ediacaran Boonall Dolomite of Kimberley, northwestern Australia: testing their biogenicity, Carbonates Evaporites, 27: 33-41, 2012.

91. Z-W. Lan and Z-Q. Chen, Exceptionally preserved microbially induced sedimentary structures from the Ediacaran post-glacial successions in the Kimberley region, northwestern Australia, Precambrian Research, 200-203: 1-25, 2012.

92. S.R. Law, R. Narsai, N.L. Taylor, E. Delannoy, C. Carrie, E. Giraud, A.H. Millar, I. Small and J. Whelan, Nucleotide and RNA metabolism prime translational initiation in the earliest events of mitochondrial biogenesis during arabidopsis germination, Plant Physiology, 158(4): 1610-1627, 2012.

93. Y-K. Leonga, J. Teo, E. Teha, J. Smith, J. Widjaja, J-X. Lee, A. Fourieb, M. Faheyb and R. Chenc, Controlling attractive interparticle forces via small anionic and cationic additives in kaolin clay slurries, Chemical Engineering Research and Design, 90: 658-666, 2012.

94. Y.M. Liew, R.A. McLaughlin, F.M. Wood and D.D. Sampson, Motion correction of in vivo three-dimensional optical coherence tomography of human skin using a fiducial marker, Biomedical Optics Express, 3(8): 1774-1786, 2012.

95. M.D. Linden and H.A. Tran, Overcoming aspirin treatment failure in diabetes, Critical Reviews in Clinical Laboratory Sciences, 49(5-6): 183-198, 2012.

96. I. Ling, Y. Alias, M.S.A. Rahim, B.W. Skelton, L.T. Byrne and C.L. Raston, Axially aligned confinement of 1,4-Bis (triethylammoniomethyl)benzene by two p-Sulfonatocalix[4]arenes, Australian Journal of Chemistry, 65(7): 755-762, 2012.

97. I. Ling, Y. Alias, B.W. Skelton and C.L Raston, Conformationally flexible p-sulfonated calix[5]arene binding with large bis-phosphonium cations, Crystal Growth and Design, 12(3): 1564-1570, 2012.

98. I. Ling, K.S. Iyer, C.S. Bond, A.N. Sobolev, Y. Alias and C.L. Raston, Sodium ion association via bridging water molecules for different charged p-phosphonated calix[4]arene bilayers, CrystEngComm, 14(24): 8541-8546, 2012.

99. I. Ling, Y. Alias, B.W. Skelton and C.L. Raston, Inclusion controlled lanthanide–imidazolium functionalised carboxylate complexation, Dalton Transactions, 41: 4884-4889, 2012.

100. S. Lionetto, A. Little, G. Moriceau, D. Heymann, M. Decurtins, M. Plecko, L. Filgueira and D. Cadosch, Pharmacological blocking of the osteoclastic biocorrosion of surgical stainless steel in vitro, Journal of Biomedical Materials Research Part A, 101(4): 991-997, 2012.

101. J.W. Loh, M. Saunders and L-Y. Lim, Cytotoxicity of monodispersed chitosan nanoparticles against the Caco-2 cells, Toxicology and Applied Pharmacology, 262: 273-282, 2012.

102. D. Lorenser, X. Yang and D.D. Sampson, Ultrathin fiber probes with extended depth of focus for optical coherence tomography, Optics Letters, 37(10): 1616-1618, 2012.

103. Y-J. Lu, R. Kerrich, P.A. Cawood, T.C McCuaig, C.J.R. Hart, Z-X. Li, Z-Q. Hou and L. Bagas, Zircon SHRIMP U–Pb geochronology of potassic felsic intrusions in western Yunnan, SW China: Constraints on the relationship of magmatism to the Jinsha suture, Gondwana Research, 22: 737-747, 2012.

104. M.S. Macauley, J. Chan, W.F. Zandberg, Y. He, G.E. Whitworth, K.A. Stubbs, S.A. Yuzwa, A.J. Bennet, A. Varki, G.J. Davies and D.J. Vocadlo, Metabolism of vertebrate amino sugars with N-glycolyl groups: Intracellular Î²-O-linked N-glycolylglucosamine (GlcNGc), UDP-GlcNGc,and the biochemical and structural rationale for the substrate tolerance of Î²-O-linked & beta;-N-acetylglucosaminidase, Journal of Biological Chemistry, 287(34): 28917-28931, 2012.

105. K.D.M. MaGee, G. Travers, B.W. Skelton, M. Massi, A.D. Payne and D.H. Brown, Synthesis, solid-state structures, solution behaviour and catalysis studies of nickel complexes of Bis(benzimidazolin-2-ylidene)pyridine pincer ligands*, Australian Journal of Chemistry, 65: 823-833, 2012.

106. S. Mahoney, F. Arfuso, P. Rogers, S. Hisheh, D. Brown, M. Millward and A. Dharmarajan, Cytotoxic effects of the novel isoflavone, phenoxodiol, on prostate cancer cell lines, Journal of Biosciences, 37(1): 73-84, 2012.

107. A.D. Martin, E. Houlihan, N. Morellini, P.K. Eggers, E. James, K.A. Stubbs, A.R. Harvey, M. Fitzgerald, C.L. Raston and S.A. Dunlop, Synthesis and toxicology of p-phosphonic acid calixarenes and o-alkylated analogues as potential calixarene-based phospholipids, ChemPlusChem, 77(4): 308-313, 2012.

108. M. Martyniuk, G. Parish, H. Marchand, P.T. Fini, S.P. DenBaars and L. Faraone, Nanoidentation of laterally overgrown epitazial gallium nitride, Electronic Materials Letters, 8(2): 111-115, 2012.

109. I.W. Masa Tenaya, K. Heel, P.A. Stumbles, G.E. Wilcox, Flow cytometric analysis of lymphocyte subset kinetics in Bali cattle experimentally infected with Jembrana disease virus, Veterinary Immunology and Immunopathology, 149(3-4): 167-176, 2012.

110. A.S. Mason, G. Yan, W.A. Cowling and M.N. Nelson, A new method for producing allohexaploid Brassica through unreduced gametes, Euphytica: 186, 277-287, 2012.

111. M.J. McCoy, R.A. Lake, R.G. van der Most, I.M. Dick and A.K. Nowak, Post-chemotherapy T-cell recovery is a marker of improved survival in patients with advanced thoracic malignancies., British Journal of Cancer, 25; 107(7): 1107-15, 2012.

112. A.M. McDonnell, A.J. Currie, M. Brown, K. Kania, B. Wylie, A. Cleaver, R. Lake and B.W. Robinson, Tumor cells, rather than dendritic cells, deliver antigen to the lymph node for cross-presentation, OncoImmunology, 1:1(6): 840-846, 2012.

113. R.A. McLaughlin, B.C. Quirk, A. Curatolo, R.W. Kirk, L. Scolaro, P. Robbins, B.A. Wood, C.M. Saunders and D.D. Sampson, Imaging of breast cancer with optical coherence tomography needle probes: Feasibility and initial results, IEEE J. Selected Topics in Quantum Electronics, 18(3): 1184-1191, 2012.

114. R.A. McLaughlin, X. Yang, B.C. Quirk, D. Lorenser, R.W. Kirk, P.B. Noble and D.D. Sampson, Static and dynamic imaging of alveoli using optical coherence tomography needle probes, Journal of Applied Physiology, 113(6): 967-974, 2012.

115. N. McLoughlin, D. Wacey, C. Kruber, M.R. Kilburn, I.H. Thorseth and R.B. Pedersen, Sulfur isotope evidence for a Paleoarchean sub-seafloor biosphere, Barberton, South Africa, Geology, 40(11): 1031-1034, 2012.

116. Q. Meng, Y. Liu, H. Yang, B.S. Shariat and T-H. Namb, Functionally graded NiTi strips prepared by laser surface anneal, Acta Materialia, 60: 1658-1668, 2012.

117. D.R. Mole, M.L. Fiorentini, N. Thebaud, T.C. McCuaig, K.F. Cassidy, C.L. Kirkland , M.T.D. Wingate, S.S. Romano, M.P. Doublier and E.A. Belousova, Spatio-temporal constraints on lithospheric development in the southwest–central Yilgarn Craton, Western Australia, Australian Journal of Earth Sciences: An International Geoscience Journal of the Geological Society of Australia, 59(5): 625-656, 2012.

118. N.M. Morellini, M.W. Fear, S. Rea, A.K. West, F.M. Wood and S.A. Dunlop, Reinnervation and nociception after burn injury, Wound Repair Regeneration, 20(3): 367-77, 2012.


119. A.G. Mueller, L.M. Lawrance, J. Muhling and G.D Pooley, Mineralogy and PTX relationships of the Archean Hannan South Au-Cu (Co-Bi) deposit, Kalgoorlie, Western Australia: Thermodynamic constraints on the formation of a zoned intrusion-related skarn, Economic Geology, 107: 1-23, 2012.

120. J.R. Muhling, I.R. Fletcher and B. Rassmussen, Dating fluid flow and Mississippi Valley type base-metal mineralization in the Paleoproterozoic Earaheedy Basin, Western Australia, Precambrian Research, 212-213: 75-90, 2012.

121. S. Mukai, G.R. Flematti, L.T. Byrne, P.G. Besant, P.V. Attwood and M.J. Piggott, Stable triazolylphosphonate analogues of phosphohistadine, Amino Acids, 43(2): 857-874, 2012.

122. P.P. Murmu, J. Kennedy, B.J. Ruck, G.V.M. Williams, A. Markwitz, S. Rubanov and A.A. Suvorova, Effect of annealing on the structural, electrical and magnetic properties of Gd-implanted ZnO thin films, Journal Material Science, 47: 1119-1126, 2012.

123. S. Mustafa, H.B. See, R.M. Seeber, S.P. Armstrong, C.W. White, S. Ventura, M.A. Ayoub and K.D.G. Pfleger, Identification and profiling of nove a1A-Adrenoceptor-CXC chemokine receptor 2 heteromer, The Journal of Biological Chemistry, 287(16): 12952-12965, 2012.

124. R.J. O’Donoghue, D.A. Knight, C.D. Richards, C.M. Prêle, H.L. Lau, A.G. Jarnicki, J. Jones, S. Bozinovski, R. Vlahos, S. Thiem, B.S. McKenzie, B. Wang, P. Stumbles, G.J. Laurent, R.J. McAnulty, S. Rose-John, H.J Zhu, G.P. Anderson, M.R. Ernst and S.E. Mutsaers, Genetic partitioning of interleukin-6 signalling in mice dissociates Stat3 from Smad3-mediated lung fibrosis, EMBO Molecular Medicine, 4(9): 939-51, 2012.

125. B.C. Ong and Y.K. Leong, Yield stress of oxide dispersions-intermolecular forces of adsorbed small ionic additives and particle surface roughness, The Canadian Journal of Chemical Engineering, 90: 1484-1493, 2012.

126. F.H.C. Ong, P.J. Henry and P.C. Burcham, Prior exposure to acrolein accelerates pulmonary inflammation in influenza A-infected mice, Toxicology Letters, 212(3): 241-251, 2012.

127. M. Pacton, D. Ariztegui, D. Wacey, M.R. Kilburn, C. Rollion-Bard, R. Farah and C. Vasconcelos, Going nano: A new step towards understanding the processes governing freshwater ooid formation , Geology, 40: 547-550, 2012.

128. J.L. Padilla-Gamino, K.M. Hanson, M. Stat and R.D. Gates, Phenotypic plasticity of the coral Porites rus: Acclimatization responses to a turbid environment, Journal of Experimental Marine Biology and Ecology, 434-435: 71-80, 2012.

129. L.G. Parkinson, S.M. Rea, A.W. Stevenson, F.M. Wood and M.W. Fear, The effect of nano-scale topography on keratinocyte phenotype and wound healing following burn injury, Tissue Engineering: Part A, 18(7-8): 703-14, 2012.

130. S.M. Paterson, D.H. Brown, J.A. Shaw, T.V. Vhirila and M.V. Baker, Synthesis of Poly(2-Hydroxyethyl Methacrylate) Sponges via Activators Regenerated by Electron-transfer Atom-transfer Radical Polymerization*, Australian Journal of Chemistry, 65(7): 931-934, 2012.

131. S.M. Paterson, A.M.A. Shadforth, D.H. Brown, P.W. Madden, T.V. Chirila and M.V. Baker, The sythesis and degradation of collagenase-degradable poly(2-hydroxyethyl methacrylate)-based hydrogels and sponges for potential applications as scaffolds in tissue engineering, Materials Science and Engineering C, 32(8): 2536-2544, 2012.

132. S.C. Payne, C. A Bartlett, A.R. Harvey, S.A. Dunlop and M. Fitzgerald, Myelin sheath decompaction, axon swelling and functional loss during chronic secondary degeneration in rat optic nerve, Investigative Ophthalmology and Visual Science, 53(10): 6093-6101, 2012.

133. G.J. Pinniger, T. Lavin and A.J. Bakker, Skeletal muscle weakness caused by carrageenan-induced inflammation, Muscle Nerve, 46: 413-420, 2012.

134. F.J. Pixley, Macrophage migration and its regulation by CSF-1, International Journal of Cell Biology, 501962: 1-12, 2012.

135. A. Podolska, S. Tham, R.D. Hart, R.M. Seeber, M. Kocan, U.K. Mishra, K.D.G. Pfleger, G. Parish and B.D. Nener, Biocompatibility of semiconducting AlGaN/GaN material with living cells, Sensors and Actuators B: Chemical, 169: 401-69, 2012.

136. N. Prakongkep, R.J. Gilkes, B. Singh and S. Wong, Pyrite and other sulphur minerals in giant aquic spodosols, Western Australia, Geoderma, 181-182: 78-90, 2012.

137. C.M. Prêle, M.E. Reichelt, S.E. Mutsaers, M. Davies, L.M. Delbridge, J.P. Headrick, N. Rosenthal, M.A. Bogoyevitch and M.D. Grounds, Insulin-like growth factor-1 overexpression in cardiomyocytes diminishes ex vivo heart functional recovery after acute ischemia, Cardiovascular Pathology, 21(1): 17-27, 2012.

138. D.L. Priebbenow, S.G. Stewart and F.M. Pfeffer, Asymmetric induction in domino Heck-aza-Michael reactions, Tetrahedron Letters, 53(12): 1468-1471, 2012.

139. H.M. Putnam, M. Stat, X. Pochon and R.D. Gates, Endosymbiotic flexibility associates with environmental sensitivity in scleractinian corals, Proceedings of The Royal Society B, 279: 4352-4361, 2012.

140. G. Putrino, A. Keating, M. Martyniuk, L. Faraone and J. Dell, Integrated resonant optical readout applicable to large arrays of MEMS beams, IEEE Photonics Technology Letters, 24(24): 2243-2246, 2012.

141. A. Qin, T.S. Cheng, Z. Lin, L. Cao, S.M. Chim, N.J. Palvos, M.H. Zheng and K.R. Dai, Prevention of Wear Particle-Induced Osteolysis by a Novel V-ATPase Inhibitor Saliphenylhalamide through Inhibition of Osteoclast Bone Resorption, PLoS ONE, 7(4): e34132, 2012.

142. S.C. Raftopoulos, J. George, M. Bourliere, E. Roosi, W.B. de Boer, G.P. Jeffrey, M. Bulsara, D.J. Speers, G. Mac Quillan, H.L.I. Ching, N. Kontorinis, W. Cheng, J. Flexman, S. Fermoyle, P. Rigby, L. Walsh, D. McLeod and L.A. Adams, Comparison of noninvasive models of fibrosis in chronic Hepatitis B, Hepatology International, 6(2): 457-467, 2012.

143. T. Raimondo, C. Clark, M. Hand, J. Cliff and C. Harris, High-resolution geochemical record of fluid-rock interactin in a mid-crustal shear zone: a comparative study of major element and oxygen isotope transport in garnet, Journal of Metamorphic Geology, 30(3): 255-280, 2012.

144. B. Rasmussen, I.R. Fletcher, A. Bekker, J.R. Muhling, C.J. Gregory and A.M. Thorne, Deposition of 1.88 Ga iron formations as a consequence of rapid crustal growth, Nature, 484: 498-501, 2012.

145. B. Rassmussen, I.R. Fletcher, C.J. Gregory, J.R. Muhling and A.A. Suvorova, Tranquillityite: The last lunar mineral comes down to earth, Geology, 40: 83-86, 2012.

146. J.E. Rixson, T. Chaloner, C.H. Heath, L.F. Tietze and S.G. Stewart, The development of domino reactions incorporating the Heck Reaction: The formation of N-Heterocycles, European Journal of Organic Chemistry, : 544-558, 2012.

147. G.J. Rizzotto and L.A. Hartmann, Geological and geochemical evolution of the Trincheira Complex, a Mesoproterozoic ophiolite in the southwestern Amazon craton, Brazil, Lithos, 148: 277-295, 2012.


148. L.M. Roger, A.J. Richardson, A.D. McKinnon, B. Knott, R. Matear and C. Scadding, Comparison of the shell structure of two tropical Thecosomata (Creseis acicula and Diacavolinia longirostris) from 1963 to 2009: potential implications of declining aragonite saturation, ICES Journal of Marine Science, 69(3): 465-474, 2012.

149. J. Rodger, E.S. Drummond, M. Hellstrom, D. Robertson and A.R. Harvey, Long-term gene therapy causes transgene-specific changes in the morphology of regenerating retinal ganglion cells, PLoS ONE, 7(2): e31061, 2012.

150. R.A. Ruhayel, J.S. Langner, M.J. Oke, S.J. Berners-Price, I. Zgani and N.P. Farrell, Chimeric platinum-polyamines and DNA binding. Kinetics of DNA interstrand cross-link formation by dinuclear platinum complexes with polyamine linkers, Journal of the American Chemical Society, 134(16): 7135-7146, 2012.

151. J. Li, H. Ru, H. Yang and Y. Liu, Liquid–solid reactions and microstructure of SiC-5120 steel composite brake material, Metallurgical and materials Transactions A, 43A: 658-664, 2012.

152. P. Salama, C. Stewart, C. Forrest, C. Platell and B. Lacopetta, FOXP3+ cell density in lymphoid follicles from histologically normal mucosa is a strong prognostic factor in early stage colon cancer , Cancer Immunology Immunotherapy, 61 (8): 1183-1190, 2012.

153. D.S. Sarma, N.J. McNaughton, E. Belusova, M.R. Mohan and I.R. Fletcher, Detrital zircon U–Pb ages and Hf-isotope systematics from the Gadag Greenstone Belt: Archean crustal growth in the western Dharwar Craton, India, Gondwana Research, 22: 843-854, 2012.

154. A. Scaffidi, M.T. Waters, C.S. Bond, K.W. Dixon, S.M. Smith, E.L. Ghisalberti and G.R. Flematti, Exploring the molecular mechanism of karrikins and strigolactones, Bioorganic and Medicinal Chemistry Letters, 22(11): 3743-3746, 2012.

155. A. Scaffidi, M.T. Waters, B.W. Skelton, C.S. Bond, A.N. Sobolev, R. Bythell-Douglas, A.J. McKinley, K.W. Dixon, E.L. Ghisalberti, S.M. Smith and G.R. Flematti, Solar irradiation of the seed germination stimulant karrikinolide produces two novel head-to-head cage dimers, Organic & Biomolecular Chemistry, 10: 4069-4073, 2012.

156. L. Scolaro, R.A. McLaughlin, B.R. Klyen, B.A. Wood, P.D. Robbins, C.M. Saunders, S.L. Jacques and D.D. Sampson, Parametric imaging of the local attenuation coefficient in human axillary lymph nodes assessed using optical coherence tomography, Biomedical Optics Express, 3(2): 366-379, 2012.

157. L. Scolaro, D. Lorenser, R.A. McLaughlin, B.C. Quirk, R.W. Kirk and D.D. Sampson, High-sensitivity anastigmatic imaging needle for optical coherence tomography, Optics Letters, 37(24): 5247-5249, 2012.

158. S. Sharma, H.A.E. Benson, T.K.S. Mukkur, P. Rigby and Y. Chen, Preliminary studies on the development of IgA-loaded chitosan-dextran sulphate nanoparticles as a potential nasal delivery system for protein antigens, Journal of Microencapsulation, : 1-12, 2012.

159. K. Shirai, K. Sowa, T. Watanabe, Y. Sano, T. Nakamura and P. Clode, Visualization of sub-daily skeletal growth patterns in massive Porites corals grown in Sr-enriched seawater, Journal of Structural Biology, 180: 47-56, 2012.

160. M.W. Simas, M. Guerra-Sommer, M. Cazzulo-Klepzig, R. Menegat, J.O.S. Santos, J.A.F. Ferreira and I. Degani-Schmidt, Geochronological correlation of the main coal interval in Brazilian Lower Permian: Radiometric dating of tonstein and calibration of biostratigraphic framework, Journal of South American Earth Sciences, 39: 1-15, 2012.

161. I. Sonntag, C. Laukamp and S.G. Hagemann, Low potassium hydrothermal alteration in low sulfidation epithermal systems as detected by IRS and XRD: An example from the Co–O mine, Eastern Mindanao, Philippines, Ore Geology Reviews, 45: 47-60, 2012.

162. S. Sood, I.A. Malecki, A. Tawang and G.B. Martin, Survival of emu (dromaius novaehollandiae) sperm preserved at subzero temperatures and different cryoprotectant concentrations, Theriogenology, 78(7): 1557-1569, 2012.

163. A.N. Sudjana, C.F. Carson, K.C. Carson, T.V. Riley and K.A. Hammer, Candida albicans adhesion to human epithelial cells and polystyrene and formation of biofilm is reduced by sub-inhibitory Melaleuca alternifolia (tea tree) essential oil, Medical Mycology, 87(8): 863-870, 2012.

164. R. Sultana, J. Yang and X. Hu, Deposition of micro-porous hydroxyapatite/tri-calcium phosphate coating on zirconia-based substrate, Rapid Communication of the American Ceramic Society, 95(4): 1212-1215, 2012.

165. Z. Sun, J. Jeyaraman, S. Sun, X. Hu and H. Chen, Carbon-fiber aluminum-foam sandwich with short aramid-fiber interfacial toughening, Composites Part A: Applied Science and Manufacturing, 43(11): 2059-2064, 2012.

166. A.A. Suvorova, S. Rubanov, A.V. Suvorov, Structural and compositional complexity of nitrogen implantation in silicon carbide, Nuclear instruments and Methods in Physics Research B, 272: 462-465, 2012.

167. Y.M. Syah and E.L. Ghisalberti, More phenolic derivatives with an irregular sesquiterpenyl side chain from Macaranga pruinosa, The Natural Products Journal, 2: 45-49, 2012.

168. S.J. Taylor, T.S. Mann and P.J. Henry, Influence of influenza A infection on capsaicin-induced responses in murine airways, The Journal of Pharmacology and Experimental Therapeutics, 340(2): 377-385, 2012.

169. E-J The, Y-K. Leong and Y. Liu, The effects of absorbed fumaric acid on dispersions of rough titania particles, Powder Technology, 223: 110-115, 2012.

170. E.C. Thomas, T. Lee-Pullen, P. Rigby, P.E. Hartmann, J. Xu and N. Zeps, Receptor activator of NF-KB ligand (RANKL) promotes proliferation of a putative mammary stem cell unique to the lactating epithelium, Stem Cells, 60(6): 1255-1264, 2012.

171. N.E. Timms, S.M. Reddy, J.D. Fitz Gerald, L. Green and J.R. Muhling, Inclusion-localised crystal-plasticity, dynamic porosity, and fast-diffusion pathway gereration in zircon, Journal of Structural Geology, 35: 78-89, 2012.

172. E. Tohver, C. Lana, P.A. Cawood, I.R. Fletcher, F. Jourdan, S. Sherlock, B. Rasmussen, R.I.F. Trindade, E. Yokoyama, C.R. Souza Filho and Y. Marangoni, Geochronological constraints on the age of a Permo–Triassic impact event: U–Pb and 40Ar/39Ar results for the 40 km Araguainha structure of central Brazil, Geochimica et Cosmochimica Acta, 86: 214-227, 2012.

173. J. Toster, C. Harnagea, K.S. Iyer, F. Rosei and C.L. Raston, Controlling anatase coating of diatom frustules by varying the binding layer, CrystEngComm, 14(10): 3446-3450, 2012.

174. C.D. Treiber, M Salzer, J. Riegler, N. Edelman, C. Sugar, M. Breuss, P. Pichler, H. Cadiou, T.C. Iancu, M.F. Lythgoe, M. Saunders, J. Shaw and D.A. Keays, Clusters of iron rich cells in the upper beak of the pigeon are macrophages not magnetosensitive neurons, Nature, 484(7394): 367-370, 2012.


175. N.N. Vagaja, H.R. Chinnery, N. Binz, J.M. Kezic, E.P. Rakoczy and P.G. McMenamin, Changes in Murine Hyalocytes Are Valuable Early Indicators of Ocular Disease, Investigative Opthamology and Visual Science, 53(3): 1445-1451, 2012.

176. D. Wacey, Earliest evidence for life on Earth: An Australian perspective, Australian Journal of Earth Sciences, 59: 153-166, 2012.

177. D. Wacey, S. Menon, L. Green, D. Gerstmann, C. Kong, N. Mcloughlin, M. Saunders and M. Brasier, Taphonomy of microfossils from the ~3400 Ma Strelley Pool Formation and ~1900 Ma Gunflint Formation: new insights using a focused ion beam, Precambrian Research, 220-221: 234-250, 2012.

178. M. Wang, Y. Liu and H. Yang, A unified thermodynamic theory for the formation of anodized metal oxide structures, Electrochimica Acta, 62: 424-432, 2012.

179. K. Wang, J. Wu, R.E. Day and T.B. Kirk, Utilizing confocal microscopy to measure refractive index of articular cartilage, Journal of Microscopy, 248(3): 281-291, 2012.

180. M. Wang, Y. Liu, D. Zhang and H. Yang, Anodization process of Sn in oxalic acid at low applied voltages, Electrochimica Acta, 59: 441-448, 2012.

181. K.A. Weber, T.L. Spanbauer, D. Wacey, M.R. Kilburn, D.B. Loope and R.M. Kettler, Biosignatures link microorganisms to iron mineralization in a paleoaquifer, Geology, 40(8): 747-750, 2012.

182. A. Weeden, K.J. Hartlieb and L.Y. Lim, Preparation and physicochemical characterization of a novel paclitaxel-loaded amphiphilic aminocalixarene nanoparticle platform for anticancer chemotherapy, Journal of Pharmacy and Pharmacology, 64(10): 1403-1411, 2012.

183. J. Wells, M.R. Kilburn J.A. Shaw, C.A. Bartlett, A.R. Harvey, S.A. Dunlop and M. Fitzgerald, Early in vivo changes in calcium ions, oxidative stress markers, and ion channel immunoreactivity following partial injury to the optic nerve, Journal of Neuroscience Research, 90: 606-618, 2012.

184. R.P.M. Wong, G.R. Flematti and T.M.E. Davis, Investigation of volatile organic biomarkers derived from Plasmodium falciparum in vitro, Malaria Journal, 11: 314, 2012.

185. F.M. Wood, N. Giles, A. Stevenson, S. Rea and M. Fear, Characterisation of the cell suspension harvested from the dermal epidermal junction using a ReCell® kit, Burns, 314(1): 44-51, 2012.

186. P.J. Wright, S. Muzzioli, M.V. Werrett, P. Raiteri, B.W. Skelton, D.S. Silvester, S. Stagni and M. Massi, Synthesis, photophysical and electrochemical investigation of dinuclear tetrazolato-bridged rhenium complexes, Organometallics, 31: 7566-7578, 2012.

187. X. Xu, H. Ynag and Y. Liu, Self-assembled structures of CuO primary crystals synthesized from Cu(CH3COO)2–NaOH aqueous systems, CrystEngComm, 14: 5289-5298, 2012.

188. F.M. Yasin, R.A. Boulos, B.Y. Hong, A. Cornejo, K.S. Iyer, L. Gao, H.T. Chua and C.L. Raston, Microfluidic size selective growth of palladium nano-particles on carbon nano-onions, Chemical Communications, 48(81): 10102-10104, 2012.

189. B.Y. Yeo, R.A. McLaughlin, R.W. Kirk and D.D. Sampson, Enabling freehand lateral scanning of optical coherence tomography needle probes with a magnetic tracking system, Biomedical Optics Express, 3(7): 1565-1578, 2012.

190. W. Yi, X. Hu, P. Ichim and X. Sun, Processing and properties of pressable ceramic with non-uniform reinforcement for selective-toughening, Materials Science and Engineering A, 558: 543-549, 2012.

191. E. Yusiharni and R. Gilkes, Rehydration of heated gibbsite, kaolinite and goethite: An assessment of properties and environmental significance, Applied Clay Science, 64: 61-71, 2012.

192. E. Yusiharni and R. Gilkes, Changes in the mineralogy and chemistry of a lateritic soil due to a bushfire at Wundowie, Darling Range, Western Australia, Geoderma, 191: 140-150, 2012.

193. E. Yusiharni and R. Gilkes, Minerals in the ash of Australian native plants, Geoderma, 189-190: 369-190, 2012.

194. E. Yusiharni and R. Gilkes, Short term effects of heating a lateritic podzolic soil on the availability to plants of native and added phosphate, Geoderma, 191: 132-139, 2012.

195. E.O. Zappettini, J. Chernicoff, J.O.S. Santos, M. Dalponte, E. Belousova and N. McNaughton, Retrowedge-related Carboniferous units and coeval magmatism in the northwestern Neuque´n province, Argentina, International Journal of Earth Science, 101: 2083-2104, 2012.

196. Q. Zeng, T.C. McCuaig, C.J.R. Hart, F. Jourdan, J. Muhling and L. Bagas, Structural and geochronological studies on the Liba goldfield of the West Qinling Orogen, Central China, Mineralium Deposita, 47: 799-816, 2012.

197. M. Zhang, H. Yang, Y. Liu, X. Sun, D. Zhang and D. Xue, Hydrophobic precipitation of carbonaceous spheres from fructose by a hydrothermal process, Carbon, 50: 2155-2161, 2012.

198. M. Zhang, H. Yang, Y. Liu, X. Sun, D. Zhang and D. Xue, First identification of primary nanoparticles in the aggregation of HMF, Nanaoscale Research Letters, 7(38): 1-5, 2012.

199. J-W. Zi, P.A. Cawood, W-M. Fan, E. Tohver, Y-J. Wang and T.C. McCuaig, Generation of Early Indosinian enriched mantle-derived granitoid pluton in the Sanjiang Orogen (SW China) in response to closure of the Paleo-Tethys, Lithos, 140-141: 166-182, 2012.

200. J-W. Zi, P.A. Cawood, W-M. Fan, Y-J. Wang, E. Tohver, T.C. McCuaig and T-P. Peng, Triassic collision in the Paleo-Tethys Ocean constrained by volcanic activity in SW China, Lithos, 144-145: 156-160, 2012.

201. J-W. Zi, P.A. Cawood, W-M. Fan, Y-J. Wang and E. Tohver, Contrasting rift and subduction-related plagiogranites in the Jinshajiang ophiolitic mélange, southwest China, and implications for the Paleo-Tethys, Tectonics, 31(2): 41639, 2012.

202. J. Zou, B. Zdyrko, I. Luzinov, C.L. Raston and K.S. Iyer, Regiospecific linear assembly of Pd nanocubes for hydrogen gas sensing, Chemical Communications, 48: 1033-1035, 2012.

203. J. Zou, K. Swaminathan Iyer and C.L. Raston, Pd-sodium carboxymethyl cellulose nanocomposites display a morphology dependent response to hydrogen gas, Green Chemistry, 14(4): 906-908, 2012.


Journal Cover

The cover of Geology: August 2012, Vol 40, No. 8Image: Scanning electron micrograph of microbial fossils (blue-green false color, against a false sepia color background) identifi ed in the iron-rich rind of concretions found in the Jurassic Navajo Sandstone of south-central Utah (United States). Microbial structures measure >0.5 mm wide and range from 2 to 5 mm long.

Article: “Biosignatures link microorganisms to iron mineralization in a paleoaquifer”. K. A. Weber, T. L. Spanbauer, D. Wacey, M. R. Kilburn, D. B. Loope, R. M. Kettler

IMAGE / 101917-3 COPPER SULPHIDES FROM THE

GOLDEN MILE.


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Techniques p04

Feature Story p06


Biomedical Sciences p08

IMAGE / PROJECT INVOLVED INVESTIGATING DROUGHT

RESISTANCE MECHANISMS OF A NEW PERENNIAL

HERBACEOUS PASTURE LEGUME. 100UM THICK

SECTIONS OF STEM WERE PREPARED ON A VIBRATOME

AND IMAGES TAKEN ON ZEISS AXIOSKOP OPTICAL

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FOSTER.

IMAGE /THIS ELECTRON - MICROSCOPY IMAGE

SHOWS STRUCTURES FORMED BY SELF-ASSEMBLY

OF MAGNETIC IRON-OXIDE NANOPARTICLES. A SMALL

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PARTICLES WAS ALLOWED TO DRY ON FILM. THE HIGH

SURFACE-TENSION OF THE WATER DROPLET DREW

PARTICLES TOGETHER AS IT DRIED, RESULTING IN

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