Cell Biology 2011 Spring
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Transcript of Cell Biology 2011 Spring
![Page 1: Cell Biology 2011 Spring](https://reader030.fdocuments.us/reader030/viewer/2022032721/55cf98d5550346d03399f49b/html5/thumbnails/1.jpg)
Figure 13-3 Molecular Biology of the Cell (© Garland Science 2008)
Intracellular Vesicular Traffic
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Figure 13-1 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-2 Molecular Biology of the Cell (© Garland Science 2008)
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The Molecular Mechanisms of Membrane Transport and the
Maintenance of Compartmental Diversity
There Are Various Types of Coated Vesicles
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Figure 13-5 Molecular Biology of the Cell (© Garland Science 2008)
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The Assembly of a Clathrin Coat Drives Vesicle Formation
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Figure 13-7a, b Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-7c, d Molecular Biology of the Cell (© Garland Science 2008)
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Both The Pinching-off and Uncoating of Coated Vesicles Are
Regulated Processes
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A current model of COPII-coated vesicle formation
Monomeric GTPases Control Coat Assembly
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SNARE Proteins and Targeting GTPases Guide Membrane
Transport
The postulated role of SNAREs in guiding vesicular transport
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The structure of paired SNAREs
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Interacting SNAREs Need To Be Pried Apart Before They
Can Function Again
Dissociation of SNARE pairs by NSF after a membrane fusion cycle is
completed
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Rab Proteins Help Ensure the Specificity of Vesicle Docking
A postulated role of Rab proteins in facilitating the docking of transport vesicles
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Table 13-1 Molecular Biology of the Cell (© Garland Science 2008)
Rab Proteins Help Ensure the Specificity of Vesicle Docking
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Figure 13-19a Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-19b Molecular Biology of the Cell (© Garland Science 2008)
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Transport from the ER through the Golgi
Apparatus
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Proteins Leave the ER in COPII-coated Transport Vesicles
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Only Proteins That Are Properly Folded and Assembled Can
Leave the ER
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Transport from the ER to the Golgi Apparatus Is Mediated
by Vesicular Tubular Clusters
Homotypic membrane fusion
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Vesicular tubular clusters
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The Retrieval Pathway to the ER Uses Sorting Signals
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A model for the retrieval of ER resident proteins
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Two possible models explaining the organization of the Golgi apparatus
and the transport of proteins from one cisterna to the next
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Transport from the Trans Golgi Network to Lysosomes
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Figure 13-37 Molecular Biology of the Cell (© Garland Science 2008)
Lysosomes Are Heterogeneous
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Figure 13-38 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-39 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-41 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-42 Molecular Biology of the Cell (© Garland Science 2008)
Multiple Pathways Deliver Materials to Lysosomes
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Figure 13-42a Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-42b Molecular Biology of the Cell (© Garland Science 2008)
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A Mannose 6-Phosphate Receptor Recognizes Lysosomal
Proteins in the TransGolgi Network
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Figure 13-44 Molecular Biology of the Cell (© Garland Science 2008)
The transport of newly synthesized lysosomal hydrolases to lysosomes
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Figure 13-45 Molecular Biology of the Cell (© Garland Science 2008)
The recognition of a lysosomal hydrolase
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Page 799 Molecular Biology of the Cell (© Garland Science 2008)
Transport from the TransGolgi Network to the Cell
Exterior: Exocytosis
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Figure 13-63 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-64 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-65a Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-65b Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-66a Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-66b Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-71 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-72 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-72a Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-72b Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-73 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 13-74 Molecular Biology of the Cell (© Garland Science 2008)
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Page 721 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 12-30 Molecular Biology of the Cell (© Garland Science 2008)
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Figure 12-32a Molecular Biology of the Cell (© Garland Science 2008)
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Figure 12-32b Molecular Biology of the Cell (© Garland Science 2008)
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Figure 12-33 Molecular Biology of the Cell (© Garland Science 2008)
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