Case Presentation - Pediatric Endourology kafka c.pdf · 2018-07-17 · Financial and Other...
Transcript of Case Presentation - Pediatric Endourology kafka c.pdf · 2018-07-17 · Financial and Other...
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Case Presentation - Pediatric Endourology
PA N E L :
E U G ENE M I N EV I C H , U S A | J O NAT H A N G L A S S , U K | R OY M O R AG , I S R A E L
YO R A M M O R , I S R A E L | P I N C H AS L I V N E , I S R A E L
M O D E R ATO R :
I L A N K A F KA , I S R A E L
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Financial and Other Disclosures
2
I have the following financial
interests or relationships to disclose: Disclosure code
No financial relationships N
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Case #1 10 y.o. male
VACTERL Association— ◦ Imperforated anus/ Megasigma
◦ Sacral Agenesis
◦ Lt. Renal Agenesis
End Colostomy + Partial Sigmoidectomy after birth
Age 3 ◦ Vesicostomy– Non contractile Bladder by FUDS
Age 7 ◦ Bladder Augmentation (Gastro–ileal) w/ Mitrofanoff- CIC by caregiver
◦ ACE (Malone procedure)
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CIC- 12 Fr----- 8Fr ----Trouble performing CIC ◦ Age 9- Underwent Revision of Mitrofanoff
Age 10 -Recurrent UTI’s ◦ Presents to ED with Rt. Flank Pain
◦ Finished Last course of oral Abx. one day prior
◦ US- Rt. Mild Hydroureteronephrosis , susp. 8 mm Stone distal ureter + 1 cm Bladder stone.
◦ Creat 0.7-1.2
◦ No Fever, Normal Signs
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Plan?
Ureteroscopy ◦ Access through Mitrofanoff
◦ Unable to ID Ureteral Orifice
Sub-Febrile, Normal white count, Cr. Still 1.2
Urine Culture- Pseudomonas Aeruginosa
What Now?
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IV Abx by sensitivities
Nephro-ureteral stent Placed by IR
UVJ narrowing with distended ureter- trouble working wire to bladder
Distal Ureteral Stone still ID by Fluoroscopy during placement
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Plan? ◦ Percutaneous Cistolithalopaxy
◦ 30 Fr Access Sheath
◦ Flexible URS + Laser Lithotripsy , basket extraction
◦ No Stricture seen UVJ, wide ureter
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Creatinine normalizes
Stone Analysis- Struvite 100%
Plan?
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Case #2 • 4 y.o Female
• Born Term 38 weeks
• Recurrent UTI’s from age 1-3
• VCUG –No Reflux / Normal repeat US
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Chronic Abdominal Pain
Lately - Recurrent Nausea + Vomiting
Urine – Leu+ Ery +++ Nit+
Urine Culture- Proteus Mirabilis
Normal Blood Work
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5 days on Abx according to sensitivities
No clinical improvement
US- Rt. Mild hydronephrosis, susp. 1.5 cm LP calculus
Plan?
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Plan?
Prone Mini PCNL
UP access
18Fr AS, Laser lithotripsy
Active Basket stone Retrieval
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Stone Analysis ◦ CaOxM 30%
◦ Struvite 40%
◦ CaPh. 30%
24hr. Collection ◦ Volume 1500 ml/24 hrs
◦ Normal Electrolytes
◦ Normal UA
◦ Normal Ox + Citr
◦ Neg. Cystein profile
◦ pH 7.8
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Case 3 4 yo male
Born Term, 38 weeks, C-Section d/t placenta previa
Parents- 1st degree cousins
Dx. Age 12 days- Microvillus inclusion disease - Home TPN through central line.
Recurrent line sepsis
Recurrent UTI’s- Proteus Mirabilis/ Klebsiella Pneumoniae
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24 months - Macroscopic Hematuria -Renal US- LT kidney – Small Calcifications of lower pole, no Hydronephrosis
-Urine Culture-
Klebsiella Pneumoniae
-Abx. treatment with
resolution of symptoms
-No urology Consult
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Age 27 months- Abdominal Pain ◦ Urine Culture - Proteus Mirabilis
◦ Renal US- ◦ LT KIDNEY unchanged from previous exam
◦ RT KIDNEY- Mild Hydronephrosis, multiple Calcifications, 6mm stone in UPJ
◦ No Urology Consult
◦ IV Abx. And D/C
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Age 29 months- Vomiting, Fever , Abdominal Pain
Severe Hyponatremia and Hypokalemia, Cr 0.77, HB 7.9
Hemodynamically Stable
Abdominal US – ◦ LT KIDNEY –Several larger Stones than in previous exam
◦ RT KIDNEY- Severe Hydronephrosis, multiple Calcifications, 6mm stone in UPJ
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PLAN?
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Bilateral Ureteral Drainage by DJS
Stabilized, Labs Normalize
PLAN?
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Recurrent line Sepsis + Recurrent Line Leaks
Anemia requiring Blood transfusions
Metabolic Imbalances
Recurrent UTI’s
Patient unfit for definitive stone clearance
PLAN?
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DJS exchange every 2 months
Age 36 months- Lt. encrusted stent- incomplete LT DJS Retrieval
PLAN?
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Percutaneous antegrade stent insertion by IR- Uneventful
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• Patient is D/C
• 3 weeks later- Massive hematuria
• Anemia- requiring transfusions
• Negative Urine cultures
• Abdominal US- Dense material in LT collecting system , Mild Hydronephrosis, Proximal Coils of DJS’s in place
• PLAN?
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• Angiography- Small Pseudo Aneurysm-Coil
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• Stabilizes Hemodinamically- D/C
• Cleared for definitive Stone Surgery after a few weeks
• Negative Urine Cultures
• Normal Labs
• PLAN?
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What’s next?
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• Bilateral Prone PCNL • 18 Fr Access- Laser Lithotripsy + Active basket stone retreival
• LT. Remnant proximal stent removal
• Bilateral antegrade ureteroscopies
• Bilateral 8 Fr Coop Nephrostomy ◦ Removal POD 2
◦ No post-op fever, Stable Hb/ Cr.
◦ D/C POD 3
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• Two Weeks later… • Gross Hematuria- HB drop 1.5 grams since d/c
• Rt. Flank Pain
• Negative Culture PLAN?
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Stone Analysis- Struvite 100%
Follow up- ◦ US 6 months- No evidence of nephrolithiasis
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Case 4 8 y.o male
12 hrs. before arrival - abdominal pain and difficulty urinating ◦ Urine Dipstick- Blood ++ Leu+
◦ Normal Labs.
◦ KUB- Susp. Urethral calcification
◦ Foley inserted at local hospital and D/C
Arrived to ED with 8Fr Foley catheter ◦ Normal Signs
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PLAN?
PLAN?
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Abdominal US ◦ Both Renal units normal, Catheter in bladder, no other findings
Negative Urine culture
Cystoscopy with Basket retrieval of stone
D/C Home
Nephrology FU- Idiopatic Hypercalciuria ◦ Thiazides + K- Citrate
Stone Analysis- CaOx Monohydrate 100%
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3 years later
Lt . Intermitent Flank Pain
US- LT. no hydro– 0.7 mm stone LP
No fever, normal labs Next Step?
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Failed LT ESWL
LT. Flexible ureteroscopy- laser lithotripsy and basket extraction
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Nephrology FU- No Change
Stone- CaOx Monohydrate 100%
3 years later ◦ Asymptomatic
◦ Urine General- Ery + Leu + pH 7
◦ Normal Labs
◦ US- Multiple calcifications in Lt. Kidney up to 7 mm size
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PLAN?
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Thank You!