Case 7a

Smear for interpretation

Case 7a

1. Leukemic Infiltration2. NHL- T cell Lymphoma3. Lymphoma/Leukemic Infiltration4. Adult T cell Lymphoma

DIAGNOSIS

LYMPHOMA/LEUKEMIC INFILTRATION

Case 7b

53y/M, presented with altered sensorium

CSF cytology

Case 7b

1. Seizary Syndrome2. Mets- Duct Ca breast/AML – M73. AML – M5/M74. Mets – NHL, Anaplastic5. AML,HCL6. Hematolymphoid Malignancy7. Multiple Myeloma

53y/M, Endoscopic biopsy – Adenoca, signet ring type, Gr III with H/O distal gastrectomy(HPE 7492/13 ) – Adenocarcinoma Gr-III

L V emboli +, 7/16 LNs mets.+ , Extranodal spread +

Post – Op. CT given

Now presenting with CNS symptoms

DIAGNOSIS

Carcinomatous Meningitis

Case 8

17y/F presented with h/o

hemiparesis, altered sensorium.

CSF Cytology

DIAGNOSIS

Case 8

1. 1. Cryptococcal Meningitis2. Myeloid Precursors – S/o Leukemoid reaction3. Positive - ? ALL, ? AML4. AML with CNS Involvement5. ?ALL , ?Lymphoma6. AML – M77. Viral Encephelitis

Reactive Lymphoid Cells

Detection of Leukemic Lymphoblasts in CSFIs Instrument-DependentAlison R. Huppmann, MD,1Susan R.Rheingold,MD,2L. Charles Bailey, MD,2 Marybeth Helfrich,BSMT, ASCP,1 and John K. Choi, MD, PhD1,3

Wescor Cytopro showed a 5- to 9-fold increasein the number of cells retrieved compared withthe equivalent slide from the Shandon CytoSpin

Am J Clin Pathol 2012;137:795-799