Case 1: Acute Post Streptococcal Glomerulonephritis

LO 13: Explain and summarize the prognosis of post streptococcal acute nephritic syndrome

Overall, the prognosis is good, with permanent renal failure being very uncommon. Complete recovery occurs in >95% of children with APSGN (Acute Post

Streptococcal Glomerulonephritis) Recurrences are extremely rare. Early death is rare in children but does occur in elderly. Mortality in the acute stage can be avoided by appropriate management of acute

renal failure, cardiac failure, and hypertension. Infrequently, the acute phase is severe and leads to glomerulosclerosis and chronic

renal disease in <2% of affected children. Complete resolution of hematuria and proteinuria in the majority of children occurs

within 3-6 weeks of the onset of nephritis. 3-10% of children may have persistent microscopic, hematuria, nonnephrotic

proteinuria, or hypertension.

Source: - Nelson Textbook of Pediatrics 19th edition- Harrison’s Principles of Internal Medicine 19th edition