Case 1 45 y male Large ulcer on right leg----4-5 months ON examination An ulcer measuring 4x6 cm on...
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Case 1 45 y male Large ulcer on right leg----4-5 months ON examination An ulcer measuring 4x6 cm on medial Aspect of right leg just above the ankle joint. There is discharge of pus and blood from The ulcer.
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Transcript of Case 1 45 y male Large ulcer on right leg----4-5 months ON examination An ulcer measuring 4x6 cm on...
Case 1
45 y maleLarge ulcer on right leg----4-5 monthsON examinationAn ulcer measuring 4x6 cm on medial Aspect of right leg just above the ankle joint.There is discharge of pus and blood fromThe ulcer.
Case 1
Pathology: Squamous cell carcinomaLocal Radiology: no bone involvementMRI Leg: an ulcerated area of 4x4 cm Staging tests--?
Case 1
3 cycles of CF given.Remarkable response seen.Complete clearance of ulcerated wound
followed by re-epithelization and scab formation.
Case 1
Case 1
further treatment--?Surgery---?Radiotherapy--?Further cycles of chemotherapy----?
Case 2
50 y male Difficulty in passing stool----3-4 monthsColonoscopy—in sigmoid colon,circumferential mass with friable mucosa causing narrowing of lumen,scope passed with difficulty.Rectum,ascending and descending colon normal. Biopsy taken.
Case 2
Pathology—Moderately differentiated adenocarcinomaCT Scan Abdomen:there is focal area of diffuse Circumferential thickening in the sigmoid colonCausing luminal narrowing and pericolonic Infiltration.It is measuring 8cm in length and
2.4cm in maximum wall thickness.
Case 2
Surgery:Tumor site----sigmoid colonSize of tumor---7.5x3.5cmSpecimen dimension---22x6cmProcedure---abdominoperineal resectionSpecimen----sigmoid colon and rectum.Tumor configuration—exophytic polypoidal.
Case 2
margins:proximal margin---5 cmDistal margin---12 cmMesentreric---9cmPerineural invasion—absentLymphovascular invasion---absentAll 15 nodes---negative
Case 2
Stage---pT3N0.Further Treatment-----?
