Carpal Tunnel Syndrome

People with MPS I (mucopolysaccharidosis) sometimes experience pain and loss of feeling in the fingertips as a result of carpal tunnel syndrome.

The wrist, or carpus, consists of eight small bones known as the carpals, which are joined by bands called ligaments.

A nerve called the median nerve passes through the space between the carpal bones and the ligaments in the wrists.

Thickening of the ligaments causes pressure on the median nerve, and this can cause irreversible nerve damage.

The nerve damage will cause the muscle at the base of the thumb to waste away and will make it hard for the person with MPS I to use his or her thumb for grasping objects.

Surgical treatment

EXERCISES