Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith...

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Career Career Development Development Grants Grants American College of Epidemiology American College of Epidemiology Annual Meeting Annual Meeting September 17, 2007 September 17, 2007 Faith Davis, PhD, University of Faith Davis, PhD, University of Illinois at Chicago Illinois at Chicago Jennifer Peel, PhD, Colorado State Jennifer Peel, PhD, Colorado State University University

Transcript of Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith...

Page 1: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Career Career Development Development

GrantsGrantsAmerican College of Epidemiology Annual American College of Epidemiology Annual

MeetingMeetingSeptember 17, 2007September 17, 2007

Faith Davis, PhD, University of Illinois at Faith Davis, PhD, University of Illinois at ChicagoChicago

Jennifer Peel, PhD, Colorado State UniversityJennifer Peel, PhD, Colorado State University

Page 2: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Career Development Career Development AwardsAwards

This presentation will focus on NIH This presentation will focus on NIH awardsawards

Many other organizations have Many other organizations have similar awards, e.g.,similar awards, e.g.,

American Cancer SocietyAmerican Cancer Society American Lung AssociationAmerican Lung Association American Heart AssociationAmerican Heart Association Centers for Disease Control and PreventionCenters for Disease Control and Prevention And likely many more…And likely many more…

Page 3: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

2828thth Annual American College of Epidemiology Annual American College of Epidemiology Meeting Meeting

Marriott Harbor Beach ResortMarriott Harbor Beach ResortFt. Lauderdale, FL.Ft. Lauderdale, FL.September 17, 2007September 17, 2007

NIH Support For Research NIH Support For Research Training And Career Training And Career

Development in Epidemiology Development in Epidemiology

NCI Cancer Training BranchNCI Cancer Training BranchLester S. Gorelic, Ph.D.Lester S. Gorelic, Ph.D.

Program Director, Clinical/Prevention SciencesProgram Director, Clinical/Prevention [email protected]@mail.nih.gov

Page 4: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Interim Branch ChiefInterim Branch Chief::

J. Carl Oberholtzer J. Carl Oberholtzer [email protected]@mail.nih.gov

Program DirectorsProgram Directors::

Lester Gorelic Lester Gorelic [email protected] [email protected] Sonia JakowlewSonia Jakowlew [email protected]@mail.nih.govShannon LemrowShannon Lemrow [email protected]@mail.nih.govNancy Lohrey Nancy Lohrey [email protected]@mail.nih.govDorkina Myrick Dorkina Myrick [email protected]@mail.nih.gov

National Cancer Institute Cancer National Cancer Institute Cancer Training Branch (CTB)Training Branch (CTB)

**

*:cancer.gov/researchandfunding/training

Page 5: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Learning ObjectivesLearning Objectives

Where to find informationWhere to find information

What is availableWhat is available

What is providedWhat is provided

How to choose the support that best How to choose the support that best

meets your needs meets your needs

Page 6: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Organization Of PresentationOrganization Of Presentation

OverviewOverview

Institutional programsInstitutional programs

Individual awardsIndividual awards

Administrative supplementsAdministrative supplements

Putting it all togetherPutting it all together

Page 7: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

ConventionsConventions

NIH funding mechanisms used in place of NIH funding mechanisms used in place of program namesprogram names

BlueBlue: NCI-specific programs: NCI-specific programs RedRed:: Clinicians onlyClinicians only Caveat: Will discuss only those programs Caveat: Will discuss only those programs

that conceivably can be used for training that conceivably can be used for training and CD in epidemiology. To be sure, and CD in epidemiology. To be sure, contact the component NIH institutecontact the component NIH institute

Page 8: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

OverviewOverview

Page 9: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Where To Find InformationWhere To Find Information

Office of Extramural Research: Office of Extramural Research: Funding:Funding: http://grants.nih.gov/training/index.htmhttp://grants.nih.gov/training/index.htm ExtramuralExtramural (Outside of NIH): (Outside of NIH):

Ruth L. Kirchstein National Research Ruth L. Kirchstein National Research Service Awards (NRSA)Service Awards (NRSA)

Career Development (K) AwardsCareer Development (K) Awards Relevant linksRelevant links

hhttp://grants.nih.gov/training/extramural.htm ttp://grants.nih.gov/training/extramural.htm http://grants.nih.gov/training/nrsa.htm http://grants.nih.gov/training/nrsa.htm http://grants.nih.gov/training/careerdevelopmentahttp://grants.nih.gov/training/careerdevelopmentawards.htmwards.htm

Page 10: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Where To Find Information, cont’dWhere To Find Information, cont’d

Office of Extramural Research: Office of Extramural Research: Funding:Funding: ExtramuralExtramural, cont’d:, cont’d:

Selected programs for special Selected programs for special populations: Research supplements to populations: Research supplements to promote diversity in health-related promote diversity in health-related research: research: http://grants.nih.gov/grants/guide/pa-http://grants.nih.gov/grants/guide/pa-files/PA-05-015.htmlfiles/PA-05-015.html

IntramuralIntramural (within NIH) (within NIH) http://www.training.nih.gov/http://www.training.nih.gov/

Individual NIH institute websitesIndividual NIH institute websites

Page 11: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Where To Find Information, cont’dWhere To Find Information, cont’d

NIH Wide Initiatives: NIH Wide Initiatives: Roadmap for Roadmap for Biomedical ResearchBiomedical Research Provides a framework of the priorities the NIH Provides a framework of the priorities the NIH

must address in order to optimize its entire must address in order to optimize its entire research portfolioresearch portfolio

Focus:Focus: New pathways to discoveryNew pathways to discovery Research teams of the futureResearch teams of the future Re-engineering the clinical research enterpriseRe-engineering the clinical research enterprise

Relevant link: Relevant link: http://nihroadmap.nih.gov/http://nihroadmap.nih.gov/

Page 12: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Where To Find Information, Where To Find Information, cont’dcont’d

NIH Wide Initiatives: NIH Wide Initiatives: Roadmap for Roadmap for Biomedical Research, cont’dBiomedical Research, cont’d Multidisciplinary Clinical Research Multidisciplinary Clinical Research

Career Development programsCareer Development programs Training an Interdisciplinary WorkforceTraining an Interdisciplinary Workforce Relevant links Relevant links

http://nihroadmap.nih.gov/ http://nihroadmap.nih.gov/ http://nihroadmap.nih.gov/clinicalresearch/clinicaltraininhttp://nihroadmap.nih.gov/clinicalresearch/clinicaltraining/futureleaders.aspg/futureleaders.asp http://grants.nih.gov/training/T_Table.htmhttp://grants.nih.gov/training/T_Table.htm

Page 13: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Institutional ProgramsInstitutional Programs

Page 14: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Institutional ProgramsInstitutional Programs

GenerallyGenerally for individuals with a limited number for individuals with a limited number of publications (if consistent with program of publications (if consistent with program selection criteria) or unable to obtain a strong selection criteria) or unable to obtain a strong institutional commitment to career development institutional commitment to career development (pre, postdoc)(pre, postdoc)

Individuals apply to an ongoing program for a Individuals apply to an ongoing program for a “slot”“slot”

Prepares an individual to apply for an individual Prepares an individual to apply for an individual research career (K) award; if appointed as a research career (K) award; if appointed as a predoc, a postdoc fellowship (F32); or an R-grantpredoc, a postdoc fellowship (F32); or an R-grant

Provides a training experience in biomedical Provides a training experience in biomedical research research

Page 15: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Institutional Programs, cont’dInstitutional Programs, cont’d

NRSANRSA T32 & T90 T32 & T90 Training experience in biomedical research Training experience in biomedical research

(T32) or interdisciplinary research (T90)(T32) or interdisciplinary research (T90) NCI supports ca. 170 T32 programs, 11 focus NCI supports ca. 170 T32 programs, 11 focus

specifically on epidemiologyspecifically on epidemiology K12K12 programs programs

““Physician scientist” career development Physician scientist” career development programsprograms

Roadmap initiativeRoadmap initiative NCINCI R25TR25T programs programs

NCI supports 40 R25T programsNCI supports 40 R25T programs 4 of the R25T’s specifically focus on 4 of the R25T’s specifically focus on

epidemiologyepidemiology

Page 16: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Institutional ProgramsInstitutional Programs

Basic provisions & requirementsBasic provisions & requirements

Page 17: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

T32 & T90 ProgramsT32 & T90 Programs

PI is an established investigatorPI is an established investigator

Trainees (predoc, postdoc) must be US Trainees (predoc, postdoc) must be US citizens or permanent residents (not for citizens or permanent residents (not for an NIH T90)an NIH T90)

Requires full-time (40 hr/week) Requires full-time (40 hr/week) commitmentcommitment

Page 18: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

T32 & T90 Programs, T32 & T90 Programs, cont’dcont’d

Up to 5 years of predoc, 3 years Up to 5 years of predoc, 3 years postdoc support is possiblepostdoc support is possible

Legislated stipend levelsLegislated stipend levels

No support for researchNo support for research

Institutional allowance for training Institutional allowance for training expenses expenses

Page 19: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Two types: Clinicians only. Clinicians & Two types: Clinicians only. Clinicians &

postdoctoral Ph.D.’spostdoctoral Ph.D.’s Provides salary and research supportProvides salary and research support Requires ≥ 75% effort commitmentRequires ≥ 75% effort commitment May have core didactic requirementsMay have core didactic requirements May require multiple mentorsMay require multiple mentors May have a specific research focus May have a specific research focus §§ Must contact sponsoring NIH institute for Must contact sponsoring NIH institute for

specificsspecifics

K12K12 ProgramsPrograms

Page 20: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

The The NCI R25TNCI R25T ProgramProgram

Curriculum-based predoc/postdoc/Jr. faculty Curriculum-based predoc/postdoc/Jr. faculty program with required didactic and program with required didactic and “laboratory” requirements“laboratory” requirements

Requires multiple mentors for each Requires multiple mentors for each appointeeappointee

Does not require 75% percent or full-time Does not require 75% percent or full-time effort commitmenteffort commitment

Support for curriculum development, Support for curriculum development, implementation, evaluation, PI salaryimplementation, evaluation, PI salary

Salary and research support for appointeesSalary and research support for appointees

Page 21: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Individual AwardsIndividual Awards

Page 22: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Individual AwardsIndividual Awards

Fellowships (F’s) and Career Awards (K’s)Fellowships (F’s) and Career Awards (K’s) Mentored ((K01, Mentored ((K01, K08)K08), , K07K07,, K23 K23, F31, F32), F31, F32) ““Transitioning” or “Cross” (K99/R00, K22’s) Transitioning” or “Cross” (K99/R00, K22’s)

awardaward Unmentored K’s (New (K22’s) & Established)Unmentored K’s (New (K22’s) & Established)

Page 23: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Individual (K&F) AwardsIndividual (K&F) Awards

Not R grantsNot R grants K & F’ s are for individuals who can demonstrate K & F’ s are for individuals who can demonstrate

the need for additional training/career the need for additional training/career development before they are fully independentdevelopment before they are fully independent

R grants are for independent investigators R grants are for independent investigators K & F’s focus on training or career K & F’s focus on training or career

development development R-grant focus is on researchR-grant focus is on research

Page 24: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Individual (K&F) AwardsIndividual (K&F) Awards

Not R grants, cont’dNot R grants, cont’d Multiple interconnected elementsMultiple interconnected elements

PI, sponsor (mentor), mentor’s statement PI, sponsor (mentor), mentor’s statement §§, , training/career development plan (K’s), research training/career development plan (K’s), research plan, institutional commitment, environmentplan, institutional commitment, environment

R grants:R grants: PI, research, environment PI, research, environment K’s generally reviewed at the institute level K’s generally reviewed at the institute level

(not F’s) (not F’s) Unsolicited R-grants (and F’s) Unsolicited R-grants (and F’s) are reviewed at CSR are reviewed at CSR

§§

Page 25: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Individual AwardsIndividual Awards

Support a research career Support a research career development experience (K’s) or development experience (K’s) or research training experience (F’s)research training experience (F’s)

Prepare an F32 awardee to apply for Prepare an F32 awardee to apply for a K-award/R-grant or a K-awardee to a K-award/R-grant or a K-awardee to apply for an R-grantapply for an R-grant

Page 26: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

FellowshipsFellowships

F’s can be used to support up to 3 years F’s can be used to support up to 3 years of mentored postdoc (F32) or up to 5 of mentored postdoc (F32) or up to 5 years (F31) of mentored predoc years (F31) of mentored predoc research trainingresearch training

Generally applicable to any area of Generally applicable to any area of biomedical researchbiomedical research

Purpose of the F-program could be to Purpose of the F-program could be to increase the diversity of the biomedical increase the diversity of the biomedical research work force (NCI F31)research work force (NCI F31)

Page 27: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

K-AwardsK-Awards

Can be used to support up to 5 years of Can be used to support up to 5 years of mentored research career development mentored research career development leading to independent investigator status leading to independent investigator status (K01, NCI (K01, NCI K07K07; ; K08, K23K08, K23) )

Can be used to provide protected Can be used to provide protected (unmentored) time to “new” investigators (unmentored) time to “new” investigators to initiate their first independent research to initiate their first independent research program (program (K22K22))

Page 28: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

K-Awards, cont’dK-Awards, cont’d

Can be used to support a mentored Can be used to support a mentored research experience followed by a research experience followed by a transition to and support during an transition to and support during an independent position (K99/R00, K22)independent position (K99/R00, K22)

Individual K’s generally applicable to a Individual K’s generally applicable to a specific aspect of biomedical research specific aspect of biomedical research (viz., basic science, patient-oriented (viz., basic science, patient-oriented research) and research career stageresearch) and research career stage

Page 29: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Individual AwardsIndividual Awards

BasicBasic Provisions & RequirementsProvisions & Requirements

Page 30: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Mentored Individual AwardsMentored Individual Awards

FellowshipsFellowships: F31,F32: F31,F32 Need a sponsor Need a sponsor Need publications (not an F31)Need publications (not an F31) Do not need institutional commitmentDo not need institutional commitment

K-AwardsK-Awards:: K01,K01,K07K07, , K08, K23K08, K23 Postdoctoral (fellows) to junior facultyPostdoctoral (fellows) to junior faculty Need a mentorNeed a mentor Need publications Need publications Need strong institutional commitmentNeed strong institutional commitment

Page 31: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Mentored Individual Awards, Mentored Individual Awards, General ProvisionsGeneral Provisions

Three (F32) to five year (F31, K’s) non-Three (F32) to five year (F31, K’s) non-renewablerenewable

US Citizen or permanent residentUS Citizen or permanent resident Require full-time (F31, F32) or at least 75% Require full-time (F31, F32) or at least 75%

effort commitments (K’s)effort commitments (K’s) MentorsMentors Provide stipends (F31, F32) or salaries (K’s)Provide stipends (F31, F32) or salaries (K’s) Provide research support (K’s)Provide research support (K’s)

Page 32: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

““Cross” Or Cross” Or “Transitioning”Awards“Transitioning”Awards

K22’sK22’s Pathway to Independence Award (K99/R00)*Pathway to Independence Award (K99/R00)*

http://grants.nih.gov/grants/new_investigators/http://grants.nih.gov/grants/new_investigators/pathway_independence.htm;pathway_independence.htm;http://grants.nih.gov/grants/guide/pa-files/PA-07-297.htmlhttp://grants.nih.gov/grants/guide/pa-files/PA-07-297.html Facilitate a “seamless” transition of Facilitate a “seamless” transition of

individuals from postdoc to independent individuals from postdoc to independent investigatorinvestigator

Supports up to 1-2 years of mentored Supports up to 1-2 years of mentored postdoctoral training (K99) postdoctoral training (K99) followed byfollowed by

Support of up to 3 years for protected time as Support of up to 3 years for protected time as an independent investigator to initiate first an independent investigator to initiate first independent research program (R00)independent research program (R00)

*NCI limits use to basic science *NCI limits use to basic science research in human cancerresearch in human cancer

Page 33: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Individual Awards: IndependentIndividual Awards: Independent

NCI Transition Career Development Awards (NCI Transition Career Development Awards (K22K22)) Provides protected time (up to 3 years) to newly Provides protected time (up to 3 years) to newly

independent* investigators to initiate their first independent* investigators to initiate their first independent research programindependent research program

NCI limits award to POR, CPCBPS;and basic NCI limits award to POR, CPCBPS;and basic science PhD’s (working in human cancer systems) science PhD’s (working in human cancer systems) in Federal intramural settingsin Federal intramural settings

Do not need a sponsoring institution at the time Do not need a sponsoring institution at the time of applicationof application

*: Moving from a postdoc position including a mentored K-grant to a first independent research position or

≤ 2 yrs in 1st independent position

Page 34: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Administrative Supplements To Administrative Supplements To Enhance Diversity In Biomedical Enhance Diversity In Biomedical

ResearchResearch NIH:NIH:

Supplements to research project grants (RPG’s)Supplements to research project grants (RPG’s) All stages in career developmentAll stages in career development

Supplements to T32 grantsSupplements to T32 grants NCI: CURE programNCI: CURE program

NCI:NCI: Supplements to R25T programs (CURE program)Supplements to R25T programs (CURE program)

Candidates contact the grant/program PICandidates contact the grant/program PI

Page 35: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Putting it all togetherPutting it all together

Page 36: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Continuum Of Opportunities Continuum Of Opportunities

PredoPredocc Post/Fellow Jr.Faculty Post/Fellow Jr.Faculty

Newly Newly IndependentIndependentMentoredMentored

T32T90/R00

R25T

F31

T32T90/R00

R25TK12

F32K07

R25TK12

K01K07

K08 K23

K22

Page 37: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Continuum Of Opportunities Continuum Of Opportunities

PredoPredocc Post/Fellow Jr.Faculty Post/Fellow Jr.Faculty

Newly Newly IndependentIndependentMentoredMentored

T32T90/R00

R25T

F31

T32T90/R00

R25TK12

F32K07

R25TK12

K01K07

K08 K23

K22 K22

K22

Page 38: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Continuum Of Opportunities Continuum Of Opportunities

PredoPredocc Post/Fellow Jr.Faculty Post/Fellow Jr.Faculty

Newly Newly IndependentIndependentMentoredMentored

T32T90/R00

R25T

F31

T32T90/R00

K22K99 R00

Page 39: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Resources For Success RatesResources For Success Rates

T32’s : 1996-2006:T32’s : 1996-2006: http://grants.nih.gov/grants/award/training/http://grants.nih.gov/grants/award/training/train9606.htmtrain9606.htm

K-awards: up to 2005:K-awards: up to 2005:

http://grant.nih.gov/training/data/rcpsucc.xlshttp://grant.nih.gov/training/data/rcpsucc.xls

Page 40: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

2828thth Annual American College of Epidemiology Annual American College of Epidemiology Meeting Meeting

Marriott Harbor Beach ResortMarriott Harbor Beach ResortFt. Lauderdale, FL.Ft. Lauderdale, FL.September 17, 2007September 17, 2007

NIH Support For Research NIH Support For Research Training And Career Training And Career

Development in Epidemiology Development in Epidemiology

NCI Cancer Training BranchNCI Cancer Training BranchLester S. Gorelic, Ph.D.Lester S. Gorelic, Ph.D.

Program Director, Clinical/Prevention SciencesProgram Director, Clinical/Prevention [email protected]@mail.nih.gov

Page 41: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Training and Career Training and Career Development Awards for Development Awards for Pre-Docs, Post-Docs and Pre-Docs, Post-Docs and

Junior FacultyJunior FacultyLynda LisabethLynda Lisabeth

University of MichiganUniversity of MichiganDepartments of Epidemiology and Departments of Epidemiology and

NeurologyNeurology

Page 42: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

BackgroundBackground

PhD in Epidemiology (2003)PhD in Epidemiology (2003) Joined neurology faculty in 2003 Joined neurology faculty in 2003 K23K23

National Institute for Neurologic National Institute for Neurologic Disorders and Stroke (NINDS)Disorders and Stroke (NINDS)

September 2005 – May 2010September 2005 – May 2010 Stroke populationStroke population

In-person interviewsIn-person interviews Blood drawsBlood draws

Page 43: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Feedback from ReviewersFeedback from Reviewers

Piggy backed on R01Piggy backed on R01 Mechanisms in placeMechanisms in place

Clear mentoring plan (frequency of Clear mentoring plan (frequency of meetings, information on past trainees, meetings, information on past trainees, etc.)etc.) Multiple mentorsMultiple mentors

Commitment to other projectsCommitment to other projects ≥≥75% effort75% effort

Overlap with ongoing studies – uniquenessOverlap with ongoing studies – uniqueness

Page 44: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Feedback from ReviewersFeedback from Reviewers

Travel – on-site research, scientific Travel – on-site research, scientific meetingsmeetings

Career development plan – mix Career development plan – mix theoretical, hands on experience and theoretical, hands on experience and coursework coursework

Support from Department ChairSupport from Department Chair Research space, start-up fundsResearch space, start-up funds

Page 45: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Lessons LearnedLessons Learned

High scientific interest, unique study High scientific interest, unique study population, need for well trained population, need for well trained researchersresearchers

Contact Project OfficerContact Project Officer Prior to submitting grantPrior to submitting grant Copy grant to PO at time of submission Copy grant to PO at time of submission

Review successful K grant applicationsReview successful K grant applications Preliminary dataPreliminary data

Feasibility of proposed researchFeasibility of proposed research

Page 46: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Lessons LearnedLessons Learned

Detailed career development planDetailed career development plan Discuss Reviewer comments with PO Discuss Reviewer comments with PO

(conference call), include mentor on (conference call), include mentor on callcall

Publication track recordPublication track record Number of publicationsNumber of publications Topic of K awardTopic of K award

Page 47: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Training and Training and Career Development Awards Career Development Awards

for Pre-Docs, Post-Docs for Pre-Docs, Post-Docs and Junior Facultyand Junior Faculty

Charlotte JoslinCharlotte JoslinUniversity of Illinois at ChicagoUniversity of Illinois at Chicago

Department Ophthalmology and Visual ScienceDepartment Ophthalmology and Visual ScienceDivision of Epidemiology, School of Public HealthDivision of Epidemiology, School of Public Health

Page 48: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

BackgroundBackground

K23 Award, National Eye Institute (NEI)K23 Award, National Eye Institute (NEI)– September 2004 – August 2009September 2004 – August 2009

Clinical research backgroundClinical research background– Mostly a clinician (70% time in clinic)Mostly a clinician (70% time in clinic)– NEI-sponsored prospective cohort study: institution Co-NEI-sponsored prospective cohort study: institution Co-

InvestigatorInvestigator– FDA clinical trials: institution PI and Co-InvestigatorFDA clinical trials: institution PI and Co-Investigator– Industry sponsored researchIndustry sponsored research

K23 AwardK23 Award– PhD in epidemiologyPhD in epidemiology– Determining corneal and intraocular lens power in post-LASIK Determining corneal and intraocular lens power in post-LASIK

eyes needing cataract surgery and intraocular lens implanteyes needing cataract surgery and intraocular lens implant

Page 49: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Feedback from ReviewersFeedback from Reviewers

1.1. Candidate and Career Development PlanCandidate and Career Development Plan– Demonstrate productivity and research Demonstrate productivity and research

potential: papers, collaborations, recent potential: papers, collaborations, recent activityactivity

– Career goals – Career goals – bebe specificspecific!!– Demonstrate aptitude and interest in goalsDemonstrate aptitude and interest in goals– Provide Provide specificspecific details about plans: details about plans:

coursework, seminars, meetings, travel, etc.coursework, seminars, meetings, travel, etc.

Page 50: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Feedback from ReviewersFeedback from Reviewers

2.2. Mentors and Institutional CommitmentMentors and Institutional Commitment– Highly qualified mentors with federal fundingHighly qualified mentors with federal funding– Diverse mentor expertiseDiverse mentor expertise– Meet training and research goals of projectMeet training and research goals of project– Institutional commitment releasing time for researchInstitutional commitment releasing time for research

3.3. Research PlanResearch Plan– ““Appropriate to primary goal . . . Appropriate to primary goal . . . a mentored a mentored

research experience which she can accomplish research experience which she can accomplish within the proposed time period and that builds on within the proposed time period and that builds on her current expertise while allowing her to expand her current expertise while allowing her to expand her skills in new areasher skills in new areas.”.”

Page 51: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Feedback from ReviewersFeedback from Reviewers

3.3. Research Plan (continued)Research Plan (continued)Well conceivedWell conceived

Important clinical problemImportant clinical problem

Include preliminary resultsInclude preliminary results

Be aware that it may be reviewed as R01!!Be aware that it may be reviewed as R01!!

Page 52: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Lessons LearnedLessons Learned

Career development proposal should build on Career development proposal should build on current expertise and develop skills in new areascurrent expertise and develop skills in new areas– Use caution too avoid research projects too similar to Use caution too avoid research projects too similar to

mentor’s existing research and interests mentor’s existing research and interests – Demonstrate independence in proposalDemonstrate independence in proposal

Mentor selection criticalMentor selection critical– Establish relationshipsEstablish relationships– Mentors selected are usually local; however, Mentors selected are usually local; however,

commuting relationships allowedcommuting relationships allowed

Page 53: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Lessons LearnedLessons Learned

Review successful career development proposalsReview successful career development proposals

Know and communicate with your project officer!!Know and communicate with your project officer!!

Page 54: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Training and Career Development Training and Career Development Awards for Pre-Docs, Post-Docs, Awards for Pre-Docs, Post-Docs,

and Junior Facultyand Junior Faculty

Lisa Metsch, Ph.D.Lisa Metsch, Ph.D.University of Miami Miller University of Miami Miller

School of MedicineSchool of MedicineDepartment of Epidemiology Department of Epidemiology

and Public Healthand Public Health

Page 55: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Funding BackgroundFunding Background

HIV/AIDS Epidemiologic and Behavioral Research HIV/AIDS Epidemiologic and Behavioral Research – Focus on HIV prevention and access to care – Focus on HIV prevention and access to care issuesissues

Received K01 award, National Institute on Drug Received K01 award, National Institute on Drug Abuse, 1997 – 2004Abuse, 1997 – 2004

Received grant from Robert Wood Johnson Received grant from Robert Wood Johnson Foundation, 1998 - 2002Foundation, 1998 - 2002

Received Large CDC awards, 1999 - 2004Received Large CDC awards, 1999 - 2004Received Two R01 awards (NIDCR and NIDA), Received Two R01 awards (NIDCR and NIDA),

2004 – 2009, 2005 – 20102004 – 2009, 2005 – 2010Served on NIH CSR HIV/AIDS IRG, 1999 – presentServed on NIH CSR HIV/AIDS IRG, 1999 – present

Reviewed K-awardsReviewed K-awards

Page 56: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Top 10 ListTop 10 List

from a perspective of a reviewerfrom a perspective of a reviewer#10:#10: Sell yourself, but do not oversell -- Sell yourself, but do not oversell --

Make reviewers think that this is the Make reviewers think that this is the perfect time for you to have a K-awardperfect time for you to have a K-award

#9#9 Mentor Dilemma – Pick the right Mentor Dilemma – Pick the right mentor and show that they will have time mentor and show that they will have time for you and they have been successful for you and they have been successful with mentoring otherswith mentoring others

#8#8 Having more than one mentor should be Having more than one mentor should be consideredconsidered

Page 57: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Top 10 ListTop 10 List

#7#7 Career Plan should address skills that Career Plan should address skills that you are lacking, should be complete you are lacking, should be complete and should make senseand should make sense

#6#6 Career Plan should include evaluation Career Plan should include evaluation plan on how you will evaluate whether plan on how you will evaluate whether your careers goals have been met your careers goals have been met

#5#5 Letters from Mentors and Letters from Mentors and Department Chair/DeanDepartment Chair/Dean are critical are critical

Page 58: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Top 10 ListTop 10 List

#4#4 Research Project should be significant Research Project should be significant but feasible – sometimes “the more but feasible – sometimes “the more simple, the better.”simple, the better.”

#3#3 Background and significance should be Background and significance should be comprehensive, tell a compelling story and comprehensive, tell a compelling story and close to perfectclose to perfect

#2#2 Methods should be well-justified and Methods should be well-justified and rationale for all decisions should be rationale for all decisions should be providedprovided

Page 59: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Top 10 ListTop 10 List

#1#1 Ideally, career plan and Ideally, career plan and research project should research project should provide foundation for you to provide foundation for you to be competitive to obtain R01 be competitive to obtain R01 level fundinglevel funding

Page 60: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

In Conclusion…In Conclusion…

This top 10 list represents the views of This top 10 list represents the views of one reviewerone reviewer

Study sections will vary in how they Study sections will vary in how they evaluate K-awardsevaluate K-awards

Review other successful K-awards Review other successful K-awards Give time to have your K-award Give time to have your K-award

reviewed by senior investigators reviewed by senior investigators before submissionbefore submission

Best of Luck!Best of Luck!

Page 61: Career Development Grants American College of Epidemiology Annual Meeting September 17, 2007 Faith Davis, PhD, University of Illinois at Chicago Jennifer.

Take Home MessageTake Home Message Read the Institute websitesRead the Institute websites Call the targeted institute contactCall the targeted institute contact Explore private organization alternativesExplore private organization alternatives Develop niche training/research planDevelop niche training/research plan Find appropriate mentorsFind appropriate mentors Draft great lettersDraft great letters Get approval for any exceptions/changesGet approval for any exceptions/changes Document all changes for audit purposesDocument all changes for audit purposes