Cappiello 2014. Antigens- red blood cell surface molecules which react with antibodies Antibodies-...

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Blood Types Cappiello 2014

Transcript of Cappiello 2014. Antigens- red blood cell surface molecules which react with antibodies Antibodies-...

Page 1: Cappiello 2014.  Antigens- red blood cell surface molecules which react with antibodies  Antibodies- carried in blood plasma.

Blood Types Cappiello

2014

Page 2: Cappiello 2014.  Antigens- red blood cell surface molecules which react with antibodies  Antibodies- carried in blood plasma.

Blood Groups and Transfusions

Page 3: Cappiello 2014.  Antigens- red blood cell surface molecules which react with antibodies  Antibodies- carried in blood plasma.

Antigens- red blood cell surface molecules which react with antibodies

Antibodies- carried in blood plasma

Antigen vs. Antibodies

Page 4: Cappiello 2014.  Antigens- red blood cell surface molecules which react with antibodies  Antibodies- carried in blood plasma.

Occur for many reasons.. Possible side effects

◦ Aggutination: clumping of red blood cells following a transfusion

◦ Cyanosis◦ Difficulty breathing

Transfusion

Page 5: Cappiello 2014.  Antigens- red blood cell surface molecules which react with antibodies  Antibodies- carried in blood plasma.

Determining Blood Type Blood Type Antigen Antibody

A A Anti-B

B B Anti-A

AB A and B Neither Anti A/B

O Neither A or B Both Anti A/B

For example, a person with only antigen A has type A blood. A person with only Antigen B has type B Blood. A person that has AB blood has both antigens A and B and a person with neither antigen A or B has O type blood.

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Blood Type of Recipient

Preferred Blood Type of Donor

Permissible Blood Type of Donor (in emergencies)

A A O

B B O

AB AB A, B, O

O O No alternatives

Blood Donations

Who is a universal donor? Why?

Who is a universal recipient? Why?

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Named after the Rhesus Monkey Considered “Antigen D”

◦ If the Rh Antigen is present on the blood cell membranes the blood is said to be Rh-positive

◦ If the Rh Antigen is absent the blood is called Rh-negative

Only 15% of the US population is Rh negative

Can be given different Rh factor

Rh Blood Group

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Blood Type Commonalities