Potent & Multi-healing power

of

Calotropis procera ….Panacea on the globe

Presented by

Dr. Sudhakar Kokate

Director PPRC, India

Panacea

Lord Hanuman

Lord Hanuman

is

worshipped

by

offering

Calotropis

leaves & flowers

Description

ᴥPlant: Calotropis procera (Ait) R. Br.

ᴥFamily: Asclepidaceae

ᴥTropical plant growing in warm climate

upto an altitude of 1050 meters

PPRC/INDIA 04

Geographical distribution

PPRC/INDIA 05

ᴥ India: abundant in Rajasthan

ᴥ Africa

ᴥ Australia

ᴥ Central and South America

PPRC/INDIA 06

ᴥ Mexico

ᴥ Caribbean islands

ᴥ Many Pacific islands

PPRC/INDIA 07

Medicinal parts of

Calotropis procera

PPRC/INDIA 08

Calotropis plant

PPRC/INDIA 09

ᴥ small shrub

ᴥ covered with cottony tomentum

PPRC/INDIA 11

Calotropis fruit

PPRC/INDIA 12

ᴥ grey - green

ᴥ inflated

ᴥ 8 – 12 cm long

PPRC/INDIA 14

Calotropis bark

PPRC/INDIA 15

ᴥ soft

ᴥ corky

ᴥ light grey

PPRC/INDIA 17

Calotropis flower

PPRC/INDIA 18

ᴥ white to pink

ᴥ spotted purple

PPRC/INDIA 20

Calotropis latex

PPRC/INDIA 21

ᴥ milky sap

ᴥ present in aerial parts

PPRC/INDIA 23

Calotropis leaf

PPRC/INDIA 24

ᴥ opposite, sub-sessile

ᴥ oblong, obviate

ᴥ short pointed, blunt at apex

ᴥ slightly leathery

ᴥ length: 7-18 cm, breadth: 5-13 cm

PPRC/INDIA 26

Calotropis root

PPRC/INDIA 27

ᴥ brown in colour

ᴥ rough on outer side

PPRC/INDIA 29

Calotropis seeds

PPRC/INDIA 30

ᴥ flat

ᴥ brown

ᴥ tuft of white hair at one end

PPRC/INDIA 32

Calotropis buds

PPRC/INDIA 33

ᴥ Flowering season: Dec – July

ᴥ blue to violet in colour

PPRC/INDIA 35

Biological & pharmacological properties

PPRC/INDIA 36

ᴥ Proteolytic

ᴥ Anti-microbial

ᴥ Larvicidal

ᴥ Nematocidal

ᴥ Anti-cancer / cytotoxic

PPRC/INDIA 37

ᴥ Anti-pyretic

ᴥ Analgesic

ᴥ Anti-inflammatory

ᴥ Anti-diarrhoeal

ᴥ Anti-fertility

PPRC/INDIA 38

ᴥ Wound-healing

ᴥ Anti-coagulant

ᴥ Hepato-protectant

ᴥ Anti-ulcer

ᴥ Anti-oxidant

PPRC/INDIA 39

ᴥ Anthelmintic

ᴥ Molluscicidal

ᴥ Pesticidal

ᴥ Insecticidal

ᴥ Schizonticidal

PPRC/INDIA 40

ᴥ Anti-microbial

ᴥ Anti-fungal

ᴥ Pro-inflammatory

ᴥ Diuretic

ᴥ Hypotensive

PPRC/INDIA 41

Chemical constituents

PPRC/INDIA 42

Whole plant:

ᴥ alkaloids ᴥ flavanoids ᴥ cardiac glycosides ᴥ sterol ᴥ uscharin

PPRC/INDIA 43

Root and root bark:

ᴥ benzoyllineolone ᴥ benzoylisolineolone ᴥ calotropterpenyl ester ᴥ calotroparsenyl acetate

PPRC/INDIA 44

Root and root bark:

ᴥ calotropfriedelenyl acetate ᴥ a-amyrin,13-amyrin ᴥ taraxasterol & its isomers

PPRC/INDIA 45

Leaves:

ᴥ Mudarine….principal active constituent ᴥ calotropin, calotropagenin ᴥ cardenolidens ᴥ stigmasterol ᴥ β-sitosterol ᴥ triterpenoid

PPRC/INDIA 46

Latex:

ᴥ sp. gravity: 1.021, contain 14.8% solids ᴥ calotropain: 2-3% ᴥ cardiac glycosides ᴥ calotropin ᴥ calactir ᴥ calotoxin

PPRC/INDIA 47

Latex:

ᴥ uscharin ᴥ uscharidin ᴥ voruscharin ᴥ triterpene ᴥ uzarigenin ᴥ syriogenin

PPRC/INDIA 48

Latex:

ᴥ proceroside ᴥ quercetin-3-rutinoside ᴥ lupeol ᴥ β-amyrin ᴥ α & β-calotropeol ᴥ 3-epimoretenol

PPRC/INDIA 49

Latex:

ᴥ procerain ᴥ histamine ᴥ trypsin

PPRC/INDIA 50

Medicinal uses

PPRC/INDIA 51

ᴥ anaemia ᴥ asthma ᴥ constipation ᴥ cough

ᴥ snake-bite ᴥ tonsillitis ᴥ purgative ᴥ leprosy

Root:

PPRC/INDIA 52

ᴥ ascites ᴥ rheumatism ᴥ diarrhoea ᴥ dysentery ᴥ dyspepsia ᴥ eczema

ᴥ elephantiasis ᴥ skin diseases ᴥ typhoid ᴥ syphilis ᴥ intestinal worms

Root bark:

PPRC/INDIA 53

ᴥ asthma ᴥ body pain ᴥ catarrh ᴥ convulsions ᴥ earache ᴥ gout

ᴥ headache ᴥ joint pain ᴥ malaria ᴥ pneumonia ᴥ rheumatic pain ᴥ swelling

Leaves:

PPRC/INDIA 54

ᴥ paralysis ᴥ typhoid ᴥ wound healing ᴥ snake bite ᴥ sores

Leaves:

PPRC/INDIA 55

ᴥ asthma ᴥ dog-bite

Leaf dust:

PPRC/INDIA 56

ᴥ asthma ᴥ cold ᴥ catarrh ᴥ cough

ᴥ dog-bite ᴥ eczema ᴥ fits ᴥ indigestion

Flowers:

PPRC/INDIA 57

ᴥ malaria ᴥ pneumonia ᴥ typhoid

Flower buds:

PPRC/INDIA 58

ᴥ tuberculosis (T.B.)

Ovary:

PPRC/INDIA 59

ᴥ aphrodisiac ᴥ carminative ᴥ lactogogue ᴥ stomachic

Bark:

PPRC/INDIA 60

ᴥ asthma ᴥ conjunctivitis ᴥ gonorrhoea ᴥ head-ache ᴥ tooth infection

ᴥ dog-bite ᴥ migraine ᴥ skin infections ᴥ snake bite ᴥ tooth-ache

Latex:

PPRC/INDIA 61

Toxic properties

PPRC/INDIA 62

After prolonged / chronic use:

ᴥ vomiting ᴥ diarrhoea ᴥ bradycardia ᴥ convulsions ᴥ allergic contact - dermatitis

PPRC/INDIA 63

After prolonged / chronic use:

ᴥ testicular necrosis ᴥ iridocyclitis ᴥ corneal oedema ᴥ congestion of eyes ᴥ frequent urination

PPRC/INDIA 64

Thank you!!

“BE WITH US”