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THE BIOTECHNOLOGY

DIRECTORY

THE INTERNATIONAL BIOTECHNOLOGY

DIRECTORY

Products,Companies, Research and Organizations

J. COOMBS & Y. R. ALSTON

M MACMILLAN PUBLISHERS

© Macmillan Publishers Ud, 1989

All rights reserved. No reproduction, copy or transmission of this publication may be made without written permission.

No paragraph of this publication may be reproduced copied, or transmitted save with written permission or in accordance with the provisions of the Copyright Act 1956 (as amended).

Any person who does any unauthorised act in relation to this publication may be liable to criminal prosecution and civil claims for damages.

Published in the United Kingdom by MACMILLAN PUBLISHERS LTD (Journals Division), 1989

Distributed by Globe Book Services Ltd Brunel Road, Houndmills Basingstoke, Hants RG21 2XS

British Library Cataloguing in Publication Data

The International biotechnology directory products, companies, research and organisations. - 1990 1. Biotechnology - Serials 660'.6'05

ISBN 978-1-349-11002-5 ISBN 978-1-349-11000-1 (eBook) DOI 10.1007/978-1-349-11000-1 ISSN 0265-3877

Published in the United States and Canada by STOCKTON PRESS, 1989 15 East 26th Street NEW YORK, NY 10010, USA

ISBN 978-0-935859-79-9

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today or request a free sampie copy

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I

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Australasia Government Departments Societies and Associations

Austria Government Departments Societies and Associations

Belgium Government Departments Societies and Associations

Brazil Government Departments Societies and Associations

Canada Government Departments Societies and Associations

Denmark Government Departments Societies and Associations

Finland Government Departments Societies and Associations

France Government Departments Societies and Associations

FR Germany Government Departments Societies and Associations

Greece Government Departments Societies and Associations

Ireland Government Departments Societies and Associa lions

CONTENTS

Preface How to Use this Directory Introduction

xv xvii xix

Part I INTERNATIONAL ORGANIZATIONS AND INFORMATION SERVICES

InternationalOrganizations International Organizations Classification Index I nformation Services

Database and Abstracting Services Journals Newsletters

Information Services Classification Index

3 8

11 11 16 33 39

Part 11 GOVERNMENT ORGANIZATIONS, ASSOCIATIONS AND SOCIETIES

Israel 49 Government Departments 49 Societies and Associations

Italy 50 Government Departments 50 Societies and Associa tions

Japan 51 Government Departments 51 Societies and Associations

Netherlands 52 Government Departments 52 Societies and Associations

Norway 53 Government Departments 56 Societies and Associations

Portugal 57 Government Departments 57 Societies and Associations

Spain 59 Government Departments 59 Societies and Associations

Sweden 60 Government Departments 61 Societies and Associations

Switzerland 64 Government Departments 65 Societies and Associations

United Kingdom 66 Government Departments 66 Societies and Associations

United States of America 67 Government Departments 67 Socielies and Associations

68 68

69 69

70 70

72 72

73 73

74 74

75 75

76 76

77 77

78 80

83 84

xiii

Australasia

Austria

Belgium

Brazil

Canada

Denmark

Finland

France

FR Germany

Greece

Ireland

xiv

Part III COMPANIES AND ORGANIZATIONS: Products and areas of research

89 Israel

100 Italy

104 Japan

112 Nctherlands

121 Norway

140 Portugal

146 Spain

150 Swedcn

175 Switzerland

201 United Kingdom

203 United States of America

INDEXES

Alphabeticallndex to Part 1Il Buyers' Guide Alphabetical Index Products, Research and Services Buyers' Guide Buyers' Guide Classification Index

MOTORIZED FILTER CHANGER for FURA-2

and other multi-wavelength applications

AI e _ .. ___ _

-•

Features: • Controlled manually or via user's computer and software

• Electronic heat-resistant shutter • Six 1" dia. filter positions • Attaches between lamp & microscope • Changes to adjacent filter< 0.5 sec.

AZI

431 469 477 588

209

212

223

244

255

257

259

265

273

284

342

Preface to the Sixth Edition This sixth edition of the Biotechnology Directory reflects the continuing need to update the activities of the industry. So once again numerous additons and revision have been made - there are over 700 completely new entries in Part 111, while a further 4000 entries have been updated and 85 companies deleted. The significant rise in the number of new products and procedures includes genetically engineered biologically active intermediates and medications which have gained regulatory approval and are now commercially available. As a result new product catgories have been added to the Buyers' Guide and the number of company products listed has been substantially increased.

Every year the volume of new and amended information is considerable and almost daunting. Once again the use of computerised data-handling has been increased and the firmer editorial control maintained, which we hope will be reflected in continued improvement in quality as weil as quantity. The sheer volume of material scanned, means that the next edition must be started as soon as the previous one has gone to press. It is therefore all the more important that our readers help keep us informed of changes and additions in their organizations. We continue to welcome all comments, which will be used in compiling the seventh edition. We encourage you, therefore, to send us promotional literature for specific products or services as weil as company or annual reports and to complete and return the questionnaire which now appears in the directory.

J Coombs and Y R Alston

September 1989

xv

Introduction

This Directory covers biotechnology in western Europe, North America, Brazil, Australasia and Japan. It provides both an overview of the extent of the present interest in this subject and a catalogue whereby suppJiers of materials and services as weil as major research activities can be identified.

In compiling this information a rather broad view of those areas of science and technology which can be regarded as being part of what is now established as biotechnology has been taken. In spite of the fact that the concept of biotechnology has now been with us for a decade or so there is still no universal agreement as to what exactly is meant by the term and a number of different concepts have evolved as folIows:

(I) Biotechnology has been used as an alternative term for industrial microbiology. It has been taken to inc1ude those aspects of biology, chemistry and engineering which have to be combined in order to develop an industrial process aimed at conversion of suitable raw materials (generally of a biological origin) to a commercially viable end product where the catalyst consists of or is derived from Jiving cells (microorganisms or cell cultures from higher organisms). In this case biotechnology covers reactor design, production of the biological catalysts, preparation of the feedstock and recovery of the desired product.

(2) Biotechnology has been used in such a way as to become synonymous with novel techniques based on recombinant DNA (genetic engineering), the formation of hybridomas and generation of monoc1onal antibodies, the molecular biology of protein synthesis, cell and tissue culture and the use of other in vitro techniques wh ich permit manipulation of biological organisms in such a way that they may be induced to produce totally new products, or to produce known compounds but in much greater quantities than normal.

(3)In a wider context biotechnology has been taken not only to inc1ude manufacturing processes, both traditional and new, but also to embrace aspects of animal and human health care, waste and pollution management, advanced plant breeding, enhanced oil recovery, mineral leaching, diagnostics and analytical equipment, biosensors, bioe1ectronics, biomass energy systems and so on.

In selecting entries for this Directory all three interpretations have been taken into account, inc1uding both the older established manufacturing processes based on fermentation to produce antibiotics, organic acids, bakers' yeast and alcoholic beverages and the new concepts such as biomass energy and genetic engineering.

Thc book is divided into three parts: I International Organizations and Information Services 11 Government Organizations, Associations and Societies 111 Companics, Research Institutes and University Departments

The third part is extended to inc1ude a detailed 'buyers' guide which lists many of the major products and/or areas of research covered by those concerns listed in part three in addition to aseries of indexes which i) lists the names of all the part 111 entries in alphabeticalorder, ii) lists all the product c1assifications in alphabetical order and iii) lists the major c1assifications under group headings such as agriculture, food and feed or waste treatment.

Part I International Organizations and Information Services

The potential of biotechnology is such that it will have dramatic effects in most areas of our Jives within the next decade: it will influence changes in raw material use, as weil as patterns of labour, health, energy, agriculture and food production. To realize this potential will require cooperation between nations with the international organizations playing an important role in such areas as the safety aspects of genetic engineering and establishment of uniform guidelines for release of manipulated organisms, patent protection, establishment of culture collections, seed banks and germplasm collections, regulation of food supplies, aspects of world and community health, and the promotion of information exchange and technology transfer as weil as encouraging joint research projects. In many of these areas existing organizations have taken on the responsibility of dealing with specific problems or needs arising from biotechnology. In addition, more specialized bodies (such as the European Federation of Biotechnology) have been set up. Within the European Community biotechnology has been identified as one of the key areas for research within the 'Framework' programme which will encompass and extend the previous activities under FAST, the Concertation Unit for Biotechnology and the Bioengineering Programme of DG XII. The United Nations has supported the establishment of a significant number of microbial research centres (MIRCEN) around the world as weil as the formation of the International Centre for Genetic Engineering and Biotechnology with facilities in New Delhi (India) and Trieste (Italy).

The rate of growth of biotechnology is such that it is impossible to assimilate all information available from primary sources. This has led to a proliferation of abstracting services, on-line databases and newsletters. As with all areas of biotechnology some have already ceased publication. However, the continued existence of others indicates that, although relatively expensive, they meet the needs of those wishing for a rapid and concise overview of what is happening with an emphasis on commercial aspects.

These publications, with contents not subjected to any type of peer review, are in addition to the many new titles which have emerged from the publishers of established scientific journals. Some of these apparently new journals are in fact derived simply by changing the name of an existing series whereas others are completely new, reflecting the emphasis of research in a particular direction.

In this Directory both types of source material are Iisted. In general, the periodicals listed are those published in the English language or with English summaries and inc1ude both journals dedicated to biotechnology and those w hich contain some articles of re1evance within the wider framework of biology, agriculture or medicine. The reason for this is that a number of the older, well-established publications attract the most important papers in a variety of fields, inc1uding biotechnology, whereas the proliferation of new journals has led to a deficiency in reports of high-quality original research. A furt her factor which is detracting from the biotechnology literature at present relates to the question of patents and prior disc1osure. In the past the primary objective of much academic research has been publication in a reputable journal. In some areas this is no longer the case, and the first indication of an important breakthrough may now be

xvii

found in snippets of sometimes unattributed information presented in the newsletlers.

To further aid the reader, the international organizations and information services each have an index listing the entries alphabetically under general categories of interest: agriculture, analytical systems and diagnostics, biological products, chemicals, consultancy services, energy and minerals, enzymes, equipment and chemicals to facilitate biotechnology, fermentation, foodjfeedstuffs, genetics, health care, horne and commercial products and waste treatment.

Part 11 Go,ernment Organizations, Associations and Societies

Part 11 presents entries which cover, alphabetically by country, central government organizations, learned societies, professional institutes and trade associations. Where the government department or ministry provides specific services or is responsible for various research facilities, these are also listed in the third part of the Directory in order that their services may be determined by reference to the products index or Buyers' Guide.

Part 111 Companies, Research Institutes and Uni,ersity Departments

Entries in part 111 comprise companies, research institutes and university departments wh ich have been arranged in alphabeticalorder by country. This edition continues the form adopted in the last year in that all entries in this part are combined for each country. This practice has been adopted due to the difficulty in reaching a satisfactory c1assification for some organizations as more universities and research institutes establish commercial activities or, as is now happening in the UK in particular, public sector research is sold off to the private sector.

Entries for universities and research institutes include not only designated centres for biotechnology but also institutes and departments with relevant activities in molecular biology, medicine, agriculture, waste treatment and biomass energy.

xviii

The companies have been selected from three groups of activity: (I) The well-established manufacturers of specific products, the consultancy firms and the engineering contractors etc, where activities can be fairly weil defined.

(2) The new biotechnology companies. Some of these as yet have no commercial products, have published little factual information about their activities and vary greatly in size and facilities from a few people with one room of their own, through ventures supported through the backup of extensive university or institutional research capabilities, to major undertakings with purpose built laboratories funded through vcnture capital funds and share offerings.

(3) The multinational companies. In some cases their activities may be difficult to fit into the framework based on country and product; activities in a given country may be restricted to the manufacture of only a few products (not necessarily employing biotechnology) plus distribution facilities for a much wider range of products. Other multinationals may be distinguished by the fact that they do not, as yet, have a significant product range based on biotechnology but are making large investments through donations to universities, joint ventures with research institutes or other companies, or acquisition of smaller companies. For the sake of consistency subsidiaries and agents for such companies are included in the lists for individual companies. Independent agents supplying goods or services on behalf of established biotechnology companies are also listed.

The Products, Services and Areas of Research Buyers' Guide consists of a listing of the products and services supplied andjor researched by the companies and other organizations listed in Part I" of the Directory. It is arranged in alphabetical order by product and each product heading is followed by a list of relevant companies, research institutes and university departments including their country of origin.

All the organizations mentioned in Part 1/1 are listed in an alphabetical index. The various products and services are detailed with complete cross referencing in the Buyers' Guide alphabetical index and further categorized in the Classification Index on the basis of their relevance to the following areas of activity: agriculture, analytical systems and diagnostics, biological products, chemicals, consultancy services, energy and minerals, enzymes, equipment and chemicals to facilitate biotechnology, fermentation, foodjfeedstuffs, genetics, health care, horne and commercial products and waste treatment. Since a given product may fall into several c1assification categories some duplication will be found in these lists.

How to use tbis directory

The directory is divided into three Parts; Part I is arranged in alphabeticalorder, and Parts II and III alphabetically by country.

Part I International Organizations and Information Senices International Organizations: The entries are arranged alphabetically. As many of the organizations are listed under acronyms, the International Organizations Classification Index at the end of the section (pp 8-10) groups the organizations under the following subject headings to make the entries easier to find. - Agriculture - Analytical Systems and Diagnostics - Biological Products - Chemicals - Consultancy Services - Energy and Minerals -Enzymes

Equipment and Chemicals to Facilitate Biotechnology - Fermentation - Food/Feedstuffs - Genetics - Health Care - Horne and Commercial Products - Waste Treatment Information Services: The entries are arranged alphabetically under the following headings: - Databases and abstracting services - Journals - N ewsletters

The Information Services Classification Index (pp 39-45) groups the entries under the same subject headings as the International Organizations Classification Index. The types of entry are indicated by codes (D - databases and abstracting services, J - journals, N - Newsletters).

Part 11 Government Organizations and Societies Entries covering government departments, learned societies, professional institutes and trade associations are listed country by country. Each country is subdivided into Government Departments and Societies and Associations. Many research organizations and university departments are also listed in Part III, and their research or services identified in the Buyers' Guide to Part 111.

Part III Companies and Organizations, Products and Areas of Research This section (and the associated Buyers' Guide) constitutes the main core of the book. Individual companies, research institutes and university departments are listed alphabetically by country and described in terms of products and research activities. In the United States section the entries are listed alphabetically by state. The Alphabetical Index to Part BI (pp 431-468) lists all the entries in alphabetical order, and indicates the country (and for the US, the state) under which the entry appears. Non- commercial organizations appear in italics to distinguish them from companies.

Indexes Alphabetical Index to Part III: Lists all the entries in Part BI as detailed above.

Buyers' Guide Alphabetical Index: Provides a summary of all the headings appearing in the Buyers' Guide. Sub­categories are cross-referred to the main headings.

Products. Research and Buyers' Guide: Many of you will find this section the most useful since all the products, research and services provided by the companies and research groups in Part BI are presented here.

The Buyers' Guide consists of just over 500 main categories in alphabeticalorder. Under each of these categories those companies, research institutes or university departments which provide the relevant products or services are listed. As in the Alphabetical Index to Part III the country (and for the US, the state) where the entry appears is shown, and non-commercial organizations are indicated by italics.

Many of the main categories have subcategories; thus, Fermentation Processes includes 17 subcategories such as Air Lift, Chemostats and Multi-stage - each of which has its own alphabetic code letter. The code letters also appear after the entry names to indicate the areas in which the various organizations are active. The absence of a code implies that the organization is involved in all the activities associated with the main category.

Ruyers' Guide Classification Index: Lists all the main categories of the Buyers' Guide with their subcategories under the same areas of interest as the Classification Indexes to Part I detailed above.

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