Brendan M. Duggan, Ph.D.Research Interests

• Applications of NMR• Natural products structure elucidation

• Obtaining structurally useful information• Increasing throughput

• Biomolecular structure and dynamics• Solution structure determination• Quantifying dynamics, e.g. folding, diffusion• Increasing throughput

• Molecular dynamics simulations• Integrating experimental NMR data with MD

Core Expertise

• Two 600 MHz (14.1 Tesla) Avance III Bruker Spectrometers• Two cryoprobes – 5mm and 1.7mm• Sample changer – 60 samples

• Protein and small molecule NMR• NMR experimental design• NMR data processing and analysis

• Amber MD simulations• Bioinformatic sequence analysis

Proposed Collaborations with SSPPS Faculty

• Bill Gerwick• Reducing NMR data acquisition time

• Ted Molinski• Increasing sensitivity

• Brad Moore• Extracting additional structurally useful information

sopnmr.ucsd.edu

sopnmr@ucsd.edu