Breastfeeding Sick and Vulnerable Newborns, Why Invest in Research?: Mary Renfrew

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BREASTFEEDING FOR INFANTS BORN TOO SOON OR TOO SMALL Why invest in research? Professor Mary J Renfrew FRSE Director, Mother and Infant Research Unit University of Dundee, Scotland [email protected]

Transcript of Breastfeeding Sick and Vulnerable Newborns, Why Invest in Research?: Mary Renfrew

Page 1: Breastfeeding Sick and Vulnerable Newborns, Why Invest in Research?: Mary Renfrew

BREASTFEEDING FOR INFANTS BORN TOO SOON OR TOO

SMALL

Why invest in research?

Professor Mary J Renfrew FRSEDirector, Mother and Infant Research Unit

University of Dundee, [email protected]

Page 2: Breastfeeding Sick and Vulnerable Newborns, Why Invest in Research?: Mary Renfrew

The challenge of infant feeding Nutritional, immunological, developmental inferiority of

breastmilk substitutes Small, preterm, sick babies and their mothers most

vulnerable – special protection needed Yet denied rights accepted unconditionally for healthy

term infants and mothers Routine practices in neonatal units contribute to

environment antagonistic to breastfeeding Limitations in current research are important barrier to

enabling breastfeeding for these babies & mothers Concerted action long overdue

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Problems with current evidence Mainly from high income settings These babies and mothers often excluded Usual methodological problems compounded

eg measurement of exposure, randomisation, confounding factors

Relatively small numbers of infants Diverse feeding modalities, changing over time – content

and methods Routine care practices interfere Long term outcomes seldom measured RCTs of breasmilk substitutes look more ‘scientific’ Knowledge needed on how to change entrenched practices

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What do we know? Increased sepsis, necrotising enterocolitis,

mortality, cognitive deficit associated with breastmilk substitutes

Reduced procedural pain when breastfed Reduced mortality, length of stay, improved

growth, attachment with kangaroo mother care including breastfeeding support

Related economic impact

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What steps are needed? Include in surveys, routine data collection: report separately Definitions of diverse feeding modalities: content & method High quality studies addressing methodological challenges

where staff confident, parents involved, barriers removed Longer term follow up

clinical, psycho-social, economic outcomes Identify ways of implementing WHO Code in neonatal

environment Basic science to explore mechanisms

immunology, endocrinology, neurology, epigenetics, psychology Ways of creating transformative, sustainable change Multidisciplinary teams, substantive long term funding

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Thank you! and key references Renfrew MJ 2016 Enabling breastfeeding for infants born

too soon or too small: a new research agenda is needed http://www.healthynewbornnetwork.org/blog/enabling-breastfeeding-infants-born-soon-small-new-research-agenda-needed/

Renfrew MJ, Craig D, Dyson L et al. Breastfeeding promotion for infants in neonatal units: a systematic review and economic analysis. Health Technol Assess 2009;13(40) http://www.journalslibrary.nihr.ac.uk/__data/assets/pdf_file/0008/64718/FullReport-hta13400.pdf

[email protected]