Brain Tumors of Childhood

8/3/2019 Brain Tumors of Childhood

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@rnei Zulmrs mg Bdekjdmmj@rnei Zulmrs mg Bdekjdmmj

Nijrfw J. Geif, L. J.Nijrfw J. Geif, L. J.


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f ntr b rn i ulmrsf ntr b rn i ulmrs


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u ts ni rfiu ts ni rfi

NjuktsNjukts BdekjrfiBdekjrfi lfjukkm`knstmlnlfjukkm`knstmln

LftLft

nstrmbytmlnnstrmbytmln

nstrmbytmlnnstrmbytmln

lfjukkm`knstmlnlfjukkm`knstmln

:td vfitrebkf:td vfitrebkf :td vfitrebkf:td vfitrebkf

fpfijylmlnfpfijylmln

bdmrmej pnpekkmlnbdmrmej pnpekkmln

fpfijylmlnfpfijylmln

bdmrmej pnpekkmlnbdmrmej pnpekkmln

lfieiaemlnlfieiaemln


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i bn rfsfitnt mii bn rfsfitnt mi

EignitsEignits

inusfn nij vmleteiainusfn nij vmleteia

ns n`mvf nijns n`mvf nij

fn nb fsfn nb fs gmbnk jfgebetsgmbnk jfgebets

vfrleni syijrmlf / dflebfrf`fkknr syijrmlfvfrleni syijrmlf / dflebfrf`fkknr syijrmlf

dfnj tektdfnj tekt


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p fl m mayp fl m may

>6>6--0?% mg nkk prelnry `rnei tulmrs0?% mg nkk prelnry `rnei tulmrs

mvfrnkk suprntfitmrenk < eigrntfitmrenkmvfrnkk suprntfitmrenk < eigrntfitmrenk -- yrsyrs

22-->? yrs>? yrs

mvfr >? yrsmvfr >? yrs


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f u m nstmlnf u m nstmln


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Bkeiebnk gfnturfsBkeiebnk gfnturfs

bfrf`fkknr luteslbfrf`fkknr lutesl -- pmstpmst--mp nij trnisefit ei >2%mp nij trnisefit ei >2%

--

Ntypebnk prfsfitntemisNtypebnk prfsfitntemis

lfieiaeteslfieiaetes lfjukkm`knstmln bfkks bmigusfj wetd kylpdmbytfslfjukkm`knstmln bfkks bmigusfj wetd kylpdmbytfs

pmstfremr gmssn dflmrrdnafpmstfremr gmssn dflmrrdnaf

lny am tm `miflny am tm `mif -- usunkky kytebusunkky kyteb


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_ntdmkmay_ntdmkmay

rmsfttfsrmsfttfs

pfrevnsbuknr psfujmrmsfttfpfrevnsbuknr psfujmrmsfttf


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f u m nstmlnf u m nstmln -- s nbtmrss nbtmrs

Bmkkeis KnwBmkkeis Knw (Naf nt jenaimses + 5 lmitds)(Naf nt jenaimses + 5 lmitds)

fxtfit mg rfsfbtemi kfss seaiegebnitfxtfit mg rfsfbtemi kfss seaiegebnit--4?% rfsfbtemi4?% rfsfbtemi

jessfleintemijessfleintemi-- lmst seaiegebnit gnbtmrlmst seaiegebnit gnbtmr -- ,,

prfprf--mp LPE nij K_mp LPE nij K_

nafnaf-- mkjfr es `fttfrmkjfr es `fttfr

destmkmaydestmkmay

jfslmpknsteb +/jfslmpknsteb +/--

fit n f bf ifs a n , ifurmin , fpfi ylnfit n f bf ifs a n , ifurmin , fpfi yln


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ntnntn

surafry nij brniemspeink errnjentemisurafry nij brniemspeink errnjentemi

6 yr jesfnsf grff survevnk 6?6 yr jesfnsf grff survevnk 6?--1?%1?%

pmmr resc armuppmmr resc armup-- 27% 6yr survevnk27% 6yr survevnk

-- --


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Bmaietevf fggfbts mg PZ nrf nafBmaietevf fggfbts mg PZ nrf naf--jfpfijnitjfpfijnit

lfnsurn`kf jfbkeiflfnsurn`kf jfbkeif


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Lfjukkm`knstmlnLfjukkm`knstmln


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PnjemarnpdsPnjemarnpds

nresfs grml vfrles 16%nresfs grml vfrles 16%

bnkbegebntemi >6%bnkbegebntemi >6%

fidnibfsfidnibfs


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Bfrf`fkknr NstrmbytmlnBfrf`fkknr Nstrmbytmln


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Lejkeif smkej vfrleni lnssLejkeif smkej vfrleni lnss

kntfrnk bysteb lnsskntfrnk bysteb lnss

--

Vsunkky jmfs imt fidnibfVsunkky jmfs imt fidnibf

lny ei nrfnslny ei nrfns lurnk imjukflurnk imjukf

nrfns mg bnkbegebnteminrfns mg bnkbegebntemi


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frf f nr strmbytmlnfrf f nr strmbytmln

Bkeiebnk prfsfitntemiBkeiebnk prfsfitntemi

Zrfntfj gmr AE jesfnsf gmr n kmia telfZrfntfj gmr AE jesfnsf gmr n kmia telf

Ntnxen ei 56%Ntnxen ei 56%

ifurmpntdyifurmpntdy


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FpejflemkmayFpejflemkmay --

>/2 mg pfjentreb pmstfremr gmssn `rnei tulmrs>/2 mg pfjentreb pmstfremr gmssn `rnei tulmrs

typebnk pntefit es 6typebnk pntefit es 6-->6 yrs mkj, lny mbbur nt niy>6 yrs mkj, lny mbbur nt niy


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_ntdmkmay_ntdmkmay

@rnei stfl eivnsemi ei 4% lebrmsbmpeb@rnei stfl eivnsemi ei 4% lebrmsbmpeb

`epdnseb pnttfri`epdnseb pnttfri pekmbytebpekmbyteb

kmmsf stfkkntf nstrmbytfskmmsf stfkkntf nstrmbytfs

Pmsfitdnk `mjefsPmsfitdnk `mjefs bytmpknsleb naarfantfs mg akenk geknlfitsbytmpknsleb naarfantfs mg akenk geknlfits


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MutbmlfMutbmlf 0? yr survevnk 9 4?% es rfpmrtfj0? yr survevnk 9 4?% es rfpmrtfj

kmw rfburrfibf rntf ngtfr tmtnk fxbesemikmw rfburrfibf rntf ngtfr tmtnk fxbesemi

0.6% ei armss tmtnk fxbesemi0.6% ei armss tmtnk fxbesemi

26% ei su`tmtnk rflmvnk26% ei su`tmtnk rflmvnk

PnjentemiPnjentemi

eietenk rnjentemi jej imt nggfbt tdf rntf mg rfburrfibfeietenk rnjentemi jej imt nggfbt tdf rntf mg rfburrfibf

rnjentemi es usfj gmr lnkeainit destmkmayrnjentemi es usfj gmr lnkeainit destmkmay

mr rfburrfibf wdfrf surafry imt gfnse`kfmr rfburrfibf wdfrf surafry imt gfnse`kf

BdflmtdfrnpyBdflmtdfrnpy

rfsfrvfj gmr lnkeainiby imt rfspmisevf tm rnjentemirfsfrvfj gmr lnkeainiby imt rfspmisevf tm rnjentemi

`rnei stfl eivnsemi nij lnkeainit destmkmay eijebntf kfss`rnei stfl eivnsemi nij lnkeainit destmkmay eijebntf kfss

gnvmrn`kf prmaimsesgnvmrn`kf prmaimses


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pfi ylmlnpfi ylmln


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pfi ylmlnpfi ylmln

>?% mg nkk bdekjdmmj tulmrs>?% mg nkk bdekjdmmj tulmrs

prfsfit wetd dfnjnbdfs, vmleteia, jepkmpen,prfsfit wetd dfnjnbdfs, vmleteia, jepkmpen,

nij net ntnxennij net ntnxen

tdrmuad gmrnleintdrmuad gmrnlein

su`nrrnbdimej sffjei ei 2%su`nrrnbdimej sffjei ei 2%


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pfi ylmlnpfi ylmln

_ntdmkmay_ntdmkmay

pfrevnsbuknr rmsfttfspfrevnsbuknr rmsfttfs


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pfi ylmlnpfi ylmln

ZrfntlfitZrfntlfit

rnjentemi gmr rfsejunk tulmr eg mkj fimuadrnjentemi gmr rfsejunk tulmr eg mkj fimuad

_rmaimses_rmaimses

ymuia naf n naims symuia naf n naims s `rnei stfl eivmkvflfit`rnei stfl eivmkvflfit

eibmlpkftf rfsfbtemieibmlpkftf rfsfbtemi


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rn i tfl mlnrn i tfl mln


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: bntfamrefs8 jeggusf, gmbnk, fxmpdyteb, nij: bntfamrefs8 jeggusf, gmbnk, fxmpdyteb, nij

jeggusfjeggusf-- lnkeainit nstrmbytmlnlnkeainit nstrmbytmln

--

rnpej prmarfssemi mg anet jysguibtemi nijrnpej prmarfssemi mg anet jysguibtemi nij

dypmeitfisf mi BZ nij Z> LPE, vnren`kfdypmeitfisf mi BZ nij Z> LPE, vnren`kf

surafry mg im `fifget mi survevnksurafry mg im `fifget mi survevnk


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@rnei Rtfl Akemln@rnei Rtfl Akemln

Gmbnk tulmrsGmbnk tulmrs ..

lny frupt nt niy surgnbflny frupt nt niy surgnbf

. .

I/W, pmmr wt anei, jepkmpen, dmnrsfifssI/W, pmmr wt anei, jepkmpen, dmnrsfifss

-- lnbrmbfpdnkylnbrmbfpdnky


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Fxmpdyteb tulmrsFxmpdyteb tulmrs

guiantf eitm tdf :td vfitrebkfguiantf eitm tdf :td vfitrebkf

bkeiebnk Dx kmiabkeiebnk Dx kmia

ntnxen nij iystnalus bmllmintnxen nij iystnalus bmllmi

eitrnbtn`kf vmleteiaeitrnbtn`kf vmleteia

dmlmafifmus fidnibflfitdmlmafifmus fidnibflfit


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frntmlnfrntmln


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frntmlnfrntmln

EignibyEigniby

nresf ei tdfnresf ei tdf lejkeiflejkeif ei tdf rfaemi mg tdf 2rjei tdf rfaemi mg tdf 2rj

vfitrebkfvfitrebkf

pmstfremr gmssn tfrntmlnspmstfremr gmssn tfrntmlns

ei tdf :td vfitrebkfei tdf :td vfitrebkf

_rfsfit wetd dyjrmbfpdnkus_rfsfit wetd dyjrmbfpdnkus


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frntmlnfrntmln

_ntdmkmay_ntdmkmay

wfkk jeggfrfitentfj mr ellnturfwfkk jeggfrfitentfj mr ellnturf

jeggfrfitentemijeggfrfitentemi


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uprntfitmr n ulmrsuprntfitmr n ulmrs

Zulmrs mg tdf bfrf`rnk dflespdfrfsZulmrs mg tdf bfrf`rnk dflespdfrfs

_eifnk rfaemi lnssfs_eifnk rfaemi lnssfs

Fxtrnpnrfibdylnk tulmrsFxtrnpnrfibdylnk tulmrs


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strmbytmlnsstrmbytmlns


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>/2 mg bdekjdmmj dflespdfrf tulmrs>/2 mg bdekjdmmj dflespdfrf tulmrs im sfx prfjekfbtemiim sfx prfjekfbtemi

pfnc eibejfibf 4pfnc eibejfibf 4-->0 yrs>0 yrs

7?7?--1?% kmia tfrl survevnk1?% kmia tfrl survevnk

-- ----

ninpknsteb nij A@L 0?ninpknsteb nij A@L 0?--2?%2?%

0?0?--:?% nij 6:?% nij 6-->6% 6 yr survevnk rfspfbtevfky>6% 6 yr survevnk rfspfbtevfky

kfptmlfieiafnk sprfnj ei >?%kfptmlfieiafnk sprfnj ei >?%


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strmbytmlnstrmbytmln

Zulmr bystZulmr byst --

keifj wetd ifmpknsteb bfkks ei 1?%keifj wetd ifmpknsteb bfkks ei 1?%

95?% rfsfbtemi95?% rfsfbtemi


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BytmrfjubtemiBytmrfjubtemi --

su`tmtnk rfsfbtemi WR. `empsy nij pnrtenksu`tmtnk rfsfbtemi WR. `empsy nij pnrtenk

rfsfbtemirfsfbtemi BBRABBRA-- rnjebnk rfsfbtemi mg lnkeainit akemlns (rnjebnk rfsfbtemi mg lnkeainit akemlns (

mvfr 5?% rfsfbtemi )mvfr 5?% rfsfbtemi )

survevnk njvnitnaf eijfpfijfit mg kmbntemi nijsurvevnk njvnitnaf eijfpfijfit mg kmbntemi nijnjhuvnit tdfrnpynjhuvnit tdfrnpy


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strmbytmlnstrmbytmln

flmt frnpyflmt frnpy

Lnkeainit nstrmbytmlnLnkeainit nstrmbytmln

:2%):2%)

ietrmsmurfnietrmsmurfn--`nsfj rf elfi`nsfj rf elfi

ErrnjentemiErrnjentemi

qufstemi mg fggebnbyqufstemi mg fggebnby

6:??6:??--7??? bAy mggfr kmiafr survevnk tdni 6??? bAy7??? bAy mggfr kmiafr survevnk tdni 6??? bAy

gmbnk gefkj lmrf bmllmi tdni wdmkf `rneigmbnk gefkj lmrf bmllmi tdni wdmkf `rnei


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pfi ylmlnspfi ylmlns

0?0?--:?% mg bdekjdmmj fpfijylmlns:?% mg bdekjdmmj fpfijylmlns l 9 gl 9 g

pfnc eibejfibf >pfnc eibejfibf >--6 yrs mkj, dnkg ; 0yrs6 yrs mkj, dnkg ; 0yrs

lmst bmllmiky nssmbentfj wetd tdf grmitnk dmri,lmst bmllmiky nssmbentfj wetd tdf grmitnk dmri, `ut`ut

ejfitebnk destmkmay ns tdmsf mg tdf pmstfremr gmssnejfitebnk destmkmay ns tdmsf mg tdf pmstfremr gmssn

mvfrnkk 6 yr jesfnsf grff survevnk es :?mvfrnkk 6 yr jesfnsf grff survevnk es :?--7?%7?%

eg armss tmtnk rfsfbtemi, tdfi 46%eg armss tmtnk rfsfbtemi, tdfi 46% resc mg rfburrfibf8 su`tmtnk rfsfbtemi, naf ;2,resc mg rfburrfibf8 su`tmtnk rfsfbtemi, naf ;2,


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AniakemakemlnsAniakemakemlns

Lexfj tulmrLexfj tulmr

lfjenk tflpmrnk km`flfjenk tflpmrnk km`f

lnkf bdekjrfilnkf bdekjrfi

_rfsfit wetd sfezurfs_rfsfit wetd sfezurfs

wfkk jflnrbntfj, bysteb, wetdmut fjflnwfkk jflnrbntfj, bysteb, wetdmut fjfln

>? yr jesfnsf>? yr jesfnsf--grff survevnk 16grff survevnk 16--5?%5?%


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; 6% mg su rntfitmrenk tulmrs ei bdekjrfi; 6% mg su rntfitmrenk tulmrs ei bdekjrfi

Pnjebnk suraebnk rfsfbtemiPnjebnk suraebnk rfsfbtemi

armss tmtnk elprmvfj survevnkarmss tmtnk elprmvfj survevnk BRG jessfleintemi bmllmiBRG jessfleintemi bmllmi

Nj uvnit trfntlfitNj uvnit trfntlfit

brniemspeink errnjentemibrniemspeink errnjentemi

bdflmtdfrnpybdflmtdfrnpy

survevnksurvevnk

;2?% nt 6 yrs;2?% nt 6 yrs


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am fi rma mlnsam fi rma mlns

00--2% mg dflespdfreb pfjentreb tulmrs2% mg dflespdfreb pfjentreb tulmrs

pmpukntemi bmitneieia mkeamjfijrmakemlnpmpukntemi bmitneieia mkeamjfijrmakemln

pfnc eibejfibf ei bdekjdmmj 7pfnc eibejfibf ei bdekjdmmj 7-->0 yrs>0 yrs grmitnk km`fsgrmitnk km`fs

grefj faa , bnkbegebntemi, lebrmdflmrrdnafsgrefj faa , bnkbegebntemi, lebrmdflmrrdnafs

--

ninpknsteb tulmrs, njj _BW bdflmninpknsteb tulmrs, njj _BW bdflm


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@fieai@fieai

bdekjdmmj mr ymuia njuktsbdekjdmmj mr ymuia njukts

,,

lny frmjf tdf eiifr tn`kf mg tdf scukklny frmjf tdf eiifr tn`kf mg tdf scukk

nssmbentfj wetd bmrtebnk jyspknsennssmbentfj wetd bmrtebnk jyspknsen


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ftnstnsfsftnstnsfs

00--4% mg pfjentreb `rnei tulmrs4% mg pfjentreb `rnei tulmrs

bfrf`rnk lftbfrf`rnk lft

96?% wekk `f luktepkf96?% wekk `f luktepkf

ifurm`knstmlnifurm`knstmln

Qekls tulmrQekls tulmr

Brain Tumors of Childhood

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