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British ApprovedNames 1999incorporating Supplement Nos 1-4
British Pharmacopoeia Commission
Published on the recommendation of theMedicines Commission
London: The Stationery Office
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Introduction
This edition marks passing the 50th anniversary of the creation of the BritishApproved Names programme which began in 1948 and in celebration of thismilestone chemical graphic formulae have been added for the first time. Inconsequence, it has been necessary to increase the page size to accommodate adouble-column format. Graphic formulae have always been provided whennew names are first published in Supplements and it has been with reluctancethat hitherto the structures had to be omitted when the names were consoli-dated in the following edition. The 116 names published in Supplements Nos.1 to 4 to the 1997 edition brings the total to 2859.
Since publication of the 1997 edition, European Community Directive 92/27/EEC has been fully implemented in the UK and this has had a profound effecton the labelling of medicinal products in which the British Approved Name(BAN) of the active ingredient differs from the corresponding RecommendedInternational Nonproprietary Name (rINN). Similarly, in the veterinarysector, European Community Directive 81/851/EEC has been fully imple-mented. These Directives require that the rINN be used and in consequence ithas been necessary to change the BAN in such cases. In most instances thisconstitutes a minor spelling change (eg indomethacin to indometacin) but insome examples a totally different name has to be used in future (eg chloramineto tosylchloramide sodium). In a small number of cases (List I, given on page000), a system of dual labelling has been adopted by the United Kingdomauthorities. For these names a period of time of not less than 5 years is beingallowed during which manufacturers will be required to label products withboth the rINN and the former BAN. At the time of going to press the draftStatutory Instrument had not been finalised. If changes are made whichimpinge on this list, the necessary amendments will be included in the nextBritish Approved Names publication. Many of the names in List II are rela-tively old and many of the corresponding products have been withdrawn fromcommerce.
As a consequence of Directive 92/27/EEC, the names shown in this edition ofBritish Approved Names may be assumed to be the rINN except where other-wise stated. Where a BAN has been changed to an rINN that moves it to adifferent alphabetical location, a cross reference has been included (egDothiepin see Dosulepin) and in such cases the old name is shown in parenthe-ses alongside the new name (eg Dosulepin (dothiepin) ). Where a name is notan rINN, the letters ‘(BAN)’ follow the name. On account of these changes inpresentation, a guide for the occasional user, How to Use This Book, is given onthe inside of the front cover. The General Notices, page 000, have also beenamended to reflect these changes.
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General Notices
British Approved Names British Approved Names are devised or selected by the British Pharmaco-poeia Commission and published by the Health Ministers on therecommendation of the Medicines Commission to provide a list of names ofsubstances or articles referred to in section 100 of the Medicines Act 1968.British Approved Names are short, distinctive names selected in accordancewith the Guiding Principles given on page 000, for substances the systematicchemical or other scientific names of which are too complex for convenientgeneral use.
It is the intention that if any substance or article to which section 99 of theAct applies becomes the subject of a monograph in the British Pharmacopoeiaor other compendium prepared under that section, the British ApprovedName (BAN) should be suitable for placing at the head of the monograph.The issue of a British Approved Name does not imply that the substance orarticle will necessarily be included in the British Pharmacopoeia or othercompendium or that the British Pharmacopoeia Commission is prepared torecommend the use of the substance or article in medicine.
Recommended INN Unless otherwise indicated each name defined in this edition is the Englishlanguage form of a Recommended International Nonproprietary Name(rINN). In cases where no rINN exits, the letters ‘(BAN)’ have been added tofollow the name in question.
British Approved Names British Approved Names (Modified), developed as described below, have the(Modified) same status under the Medicines Act 1968 as the British Approved Names
from which they are derived.
Salts When a British Approved Name exists for an acid or base, the name of thecorresponding salt should be formed by following normal chemical practicewhenever possible; the resulting name is known as a British Approved Name(Modified) (BANM).
When naming the salt of an acid the British Approved Name of which ends in-ic acid, the name of the anion is formed by changing -ic acid to -ate; the nameis preceded by that of the cation, eg valproic acid giving sodium valproate. Whennaming the salts of other acids, the name of the anion is identical to that of theacid and is followed by the name of the cation, eg ampicillin giving ampicillinsodium.
For the salts of bases, the British Approved Name of the base is followed bythe conventional anion name, eg acebutolol giving acebutolol hydrochloride. TheBritish Approved Name of a quaternary salt includes the anion and may bemodified by substitution of a different anion.
Esters Modification of names following normal chemical practice has traditionallybeen employed to provide names for esters of steroid alcohols, egbetamethasone valerate. In other esters, the names adopted will depend uponwhether the biological activity lies in the acid or alcohol or within the esteritself and on whether a British Approved Name exists for the acid or alcohol inquestion. For further recommendations on the formation of British ApprovedNames (Modified), see Guiding Principles Nos B2 and B3.
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Pronunciation Each British Approved Name, except for those of abandoned ordiscontinued substances, is provided with an indication of its pronunciationgiven in phonetic terms defined below.
Nonproprietary names of A nonproprietary name for a medicinal product combines the Britishmedicinal products Approved Name of the substance with an appropriate term drawn from the
formulary of the British Pharmacopoeia or the British Pharmacopoeia(Veterinary) or with an officially recognised descriptive term (see BritishPharmacopoeia 1999, Supplementary Chapter II B).
In cases where the substance name is a British Approved Name (Modified),the modifying term is omitted from the nonproprietary name of the product,except where there exist two or more formulations containing different formsof the basic substance. In such cases the modifying term is retained. Tablets ofbenzhexol hydrochloride, for example, are known simply as benzhexol tabletssince tablets containing benzhexol are formulated only with its hydrochloride.Promethazine, however, is formulated as tablets containing either the hydro-chloride and the teoclate salts and the nonproprietary names of the two tabletforms are promethazine hydrochloride tablets and promethazine teoclate tabletsrespectively.
Chemical nomenclature Each British Approved Name is provided with (1) a systematic chemical namein accordance with the rules of the International Union of Pure and AppliedChemistry (IUPAC) or (2) a brief statement of its biological, biotechnologicalor botanical source. However, certain concessions to long-establishednomenclature terminology in pharmaceutical chemistry are made, details ofwhich are contained in the Appendix on Structures.
The structures of a large proportion of the substances defined contain one ormore chiral centres. The British Approved Name applies only to the specificisomer or racemate indicated by the systematic chemical name, eg zamifenacinrefers only to the (R) isomer of 3-benzhydryloxy-1-[2-(1,3-benzodioxol-5-yl)ethyl]piperidine.
Structural formulae and Many of the substances defined in this edition exist as a mixture of twostereochemistry enantiomeric forms or as a mixture of four or more stereoisomers. In drawing
the structures of a single chiral centre molecules, a convention has beenadopted whereby the ‘R’ isomer has been drawn and the words and enantiomeradded beneath. Where a molecule contains two or more chiral centres, eachcentre has been identified by an asterisk (*) and the words, for example,mixture of 4 stereoisomers added beneath. In some cases a polychiral substancemay exist as a pair of stereoisomers, in which case the site of epimerisation ismarked with an asterisk (*) and the words and epimer at C* added beneath.
To promote clarity in the structural formulae the following abbreviations arefrequently used:
Me: –CH3 Bus: –CH(CH3)CH2CH3
Et: –CH2CH3 Bun: –CH2CH2CH2CH3
Pri: –CH(CH3)2 But: –C(CH3)3
Prn: –CH2CH2CH3 Ph: –C6H5
Bui: –CH2CH(CH3)2 Ac: –COCH3
The 1-letter and 3-letter codes for amino acids that constitute peptide andpolypeptide chains are defined in Appendix A, section F1.
Appendix A: Structures, page 000, gives the basic skeletal structure of someimportant groups of substances of natural origin, such as steroids,cephalosporins, penicillins, prostaglandins and opioids, showing the
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numbering system and the normal stereochemistry of each group. It providesthe systematic chemical names of certain key substances, such as penicillanicacid and prostanoic acid, which have been used as convenient and familiarbases of chemical definitions.
Chemical Abstracts Service Chemical Abstracts Service (CAS) Registry Numberscorresponding to almost Registry Numbers every British Approved Name are included in order to provide easy access to
scientific literature on any particular substance through computer databases.They are printed in italic type.
Code designations Laboratory codes are often used to identify substances during the period ofinvestigation and may appear in the scientific literature. Such codes, whereknown, are included to facilitate relating a substance described by a code to aBritish Approved Name subsequently assigned to it.
Synonyms Proposed International Nonproprietary Names and United States AdoptedNames that differ significantly from the corresponding British Approved Nameare included and are followed by ‘(pINN) or ‘(USAN)’, as appropriate.Additionally, other nonproprietary names by which a substance has beenpreviously known may be given. None of these other names should beregarded as approved synonyms.
Trade marks The list includes some trade marks, printed in SMALL CAPITALS, which mayapply to the substances, salts or other derivatives of the substances, or theirpreparations. The names are largely confined to those used in the UnitedKingdom but carry no assurance that the products are commercially available.
Discontinued substances British Approved Names that have been published for substances that have and products either been abandoned during development or are no longer commercially
available in the UK are preceded by a ‘✧ ’ symbol.
Names of products that have been discontinued in the United Kingdom sincethe previous edition have been printed in ITALICISED SMALL CAPITALS.
Action and use The statements in italics indicating the pharmacological action and/ortherapeutic use are based largely on information supplied by the manufacturerand are expressed, wherever possible, in terms of the therapeutic classificationused in the British National Formulary. The British PharmacopoeiaCommission is not in a position to comment on the efficacy of the substancewith regard to the action claimed.
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Guiding Principles
A Recommended INN will be adopted as the BAN when necessary. In caseswhere no INN exists the guiding principles given below should be used indevising or selecting new BANs.
A1. Names should be distinctive in sound and spelling. They should not beinconveniently long and should not be liable to confusion with names incommon use. They should be free from conflict with trade marks andfrom misleading connotations.
A2. The name for a substance belonging to a group of therapeutically orpharmacologically related substances should, where appropriate, showthis relationship. Names that are likely to cause alarm or expectations inpatients through an anatomical, physiological, pathological or therapeuticsuggestion should be avoided.
These primary principles are implemented by using the following secondaryprinciples:
B1. In devising the name of the first substance in a new pharmacologicalgroup, consideration should first be given to the opportunity for devisingfurther suitable names for related substances belonging to the new groupby means of a common stem (see Guiding Principle B7).
B2. In devising names for therapeutically active acids one-word names arepreferred; their salts should be named without modifying the acid name,eg, fenoprofen and fenoprofen calcium, naproxen and naproxen sodium.
B3. Names for substances that are used as salts should in general apply to theactive base or the active acid. Names for different salts of the same activesubstance should differ only in respect of the name of the inactivecounter-ion. For quaternary ammonium substances, the cation and anionshould be named as separate components.
B4. The use of an isolated letter or number should be avoided; hyphenatedconstruction is also undesirable except in the prefix co- used in names forsubstance-combinations.
B5. To facilitate the acceptance and pronunciation of British ApprovedNames in other countries, f should normally be used instead of ph, tinstead of th, i instead of y and names beginning with h should beavoided.
B6. Provided that the names suggested are in accordance with these princi-ples, names proposed by the company discovering or first developing andmarketing a pharmaceutical preparation should receive preferentialconsideration.
B7. Group relationships in British Approved Names (see Guiding PrincipleA2) should if possible be shown by using a common stem. The stemshould only be used for substances of the appropriate group. Thefollowing list contains examples of stems for groups of substances. Wherea stem is shown without any hyphens it may be used any where in thename.
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A full list of common stems is contained in Document PHARM S/NOM 15available from the the World Health Organization.
Examples:-adol analgesics
-anserin serotonin receptor antagonists (mostly 5HT2) used asantihypertensives
-ast antiasthmatics, antiallergics when not acting primarily asantihistamines
-astine antihistamines, not otherwise classifiable-azepam substances of the diazepam group
-cain- anti-arrhythmic agents with local anaesthetic activity-caine local anaesthetics
cef- antibiotics, derivatives of cephalosporanic acid-cillin antibiotics, derivatives of 6-aminopenicillanic acid
-conazole systemic antifungals of the miconazole group-dipine calcium ion channel antagonists-fibrate substances of the clofibrate group
-floxacin fluorine-containing antibacterial agents of the quinolone groupgest steroids, progestogensgli sulphonamide hypoglycaemics
-grel platelet aggregation inhibitorsio- iodine-containing contrast media
-kalim potassium channel activators-mab monoclonal antibodies:
-amab rat origin-emab hamster origin-imab primate origin-lim- lymphocyte-omab mouse origin
-bacamab bacterial-colomab colon-govomab ovary (tumours)-limomab lymphocyte-ciromab cardiovascular-lesomab infectious legions-promab prostate (tumour)-tumomab tumour (miscellaneous)-umab human origin-bacumab bacterial-tumumab tumour-virumab viral-ximab chimerical origin-ciximab cardiovascular-limimab immunomodulator
-metacin anti-inflammatory substances of the indomethacin group-mycin antibiotics produced by Streptomyces strains
-nidazole antiprotozoal substances of the metronidazole group-olol beta adrenoceptor antagonists
-oxacin antibacterial agents of the quinolone group
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-pafant platelet-activating factor antagonists-pramine substances of the imipramine group
-pride substances of the sulpiride group-pril inhibitors of angiotensin-converting enzyme
-prilat inhibitors of angiotensin-converting enzyme-profen anti-inflammatory substances of the ibuprofen group
prost prostaglandins-racetam substances of the piracetam group
-relin hypophyseal hormone release-stimulating peptides-sartan angiotensin II receptor antagonists-setron serotonin receptor antagonists (5HT3) used as hypertensives
-stat enzyme inhibitors-steine substances of the acetylcysteine group-tidine H2-receptor antagonists of the cimetidine group
-triptan 5HT1D-serotonin receptor agonists-verine spasmolytics with a papaverine-like action
-vastatin HMG CoA reductase inhibitors-vir antivirals
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List IThe following names habe been changed but for these particular names a systemof dual labelling for human medicines has been adopted by the United Kingdomauthorities. Both names are to be used for the purposes of labelling in accordancewith the relevant Statutory Instrument.
Entry in RecommendedBritish Approved Names 1997 International Nonproprietary Nameacrosoxacin rosoxacinadrenaline epinephrineamethocaine tetracainebendrofluazide bendroflumethiazidebenzhexol trihexyphenidylchlorpheniramine chlorphenaminedicyclomine dicycloverinedothiepin dosulepineformoterol formoterolflurandrenolone fludroxycortidefrusemide furosemidehydroxyurea hydroxycarbamidelignocaine lidocainemethotrimeprazine levomepromazinemethylene blue methylthioninium chloridemitozantrone mitoxantronemustine chlormethinenicoumalone acenocoumarolnoradrenaline norepinephrineoxpentifylline pentoxifyllineprocaine penicillin procaine benzylpenicillinsalcatonin calcitonin (salmon)stilboestrol diethylstilbestrolthymoxamine moxisylytethyroxine sodium levothyroxine sodiumtrimeprazine alimemazine
List II The following names are changed.
Change: To:acepifylline acefylline piperazineacinitrazole aminitrozoleallyloestrenol allylestrenolaloxidone allomethadionealphadolone alfadolonealphaxalone alfaxaloneaminacrine aminoacridineamoxycillin amoxicillinamphetamine amfetamineamylobarbitone amobarbitalamylobarbitone sodium amobarbital sodiumangiotensin amide angiotensinamideazetepa azatepabalipramine depraminebarbitone barbitalbeclomethasone beclometasone
Changes of Name
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Change: To:benorylate benorilatebenzathine penicillin benzathine benzylpenicillinbenzphetamine benzfetaminebenztropine benzatropinebethanidine betanidine1
bismuth glycollylarsanilate glycobiarsolbromocyclen bromociclenbromodiphenhydramine bromazinebuniodyl bunamiodylbupropion amfebutamonebusulphan busulfanbutamyrate butamiratebutethamate butetamatebuthalitone sodium buthalital sodiumbutobarbitone butobarbital2
butoxamine butaxaminecarbiphene carbifenecarbolonium bromide hexcarbacholine bromidecarbophenothion carbofenotioncarphenazine carfenazinecarticaine articainecellacephate cellacefatecephalexin cefalexin1
cephaloglycin cefaloglycin1
cephalonium cefalonium2
cephaloram cefaloram1
cephaloridine cefaloridine1
cephalothin cefalotin1
cephamandole cefamandole1
cephamandole nafate cefamandole nafate2
cephazolin cefazolin1
cephoxazole cefoxazolecephradine cefradinechlophedianol clofedanolchloral betaine cloral betainechloramine tosylchloramide sodiumchlorbutol chlorobutanolchlordantoin clodantoinchlorfenvinphos clofenvinfoschlorhexadol chloralodolchlormethiazole clomethiazolechlorthalidone chlortalidonechlorthenoxazin chlorthenoxazinecholecalciferol colecalciferolcholestyramine colestyramineclamoxyquin clamoxyquineclomiphene clomifeneclorgyline clorgilineclothiapine clotiapine
1these names are only proposed INNs but the changes have beenmade for conformity with other names in the relevant series2these names are not INNs but the changes have been made forconformity with other names in the respective series
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Change: To:co-carboxylase cocarboxylasecolistin sulphomethate sodium colistimethate sodiumcorticotrophin corticotropincoumaphos coumafoscromoglycic acid cromoglicic acidcrotethamide crotetamidecumetharol coumetarolcyacetazide cyacetacidecyclobarbitone calcium cyclobarbital calciumcycloprolol cicloprololcysteamine mercaptaminedanthron dantrondeoxycortone desoxycortonedesoxymethasone desoximetasonedexamphetamine dexamfetamine3
diamphenethide diamfenetidediatrizoic acid amidotrizoic aciddiazinon dimpylatedibromopropamidine dibrompropamidinedichlorphenamide diclofenamidedienoestrol dienestroldimethicone(s) dimeticonedimethindene dimetindenedimethisoquin quinisocainedimethothiazine dimetotiazinedimethyl sulphoxide dimethyl sulfoxidedioxathion dioxationdipenine bromide diponium bromidediphenidol difenidoldisulphamide disulfamidedoxybetasol doxibetasoldoxycycline hydrochloride (hemihydrate hemiethanolate) doxycycline hyclatedyclocaine dyclonineepioestriol epiestriolepithiazide epitizideetenzamide ethenzamideethacrynic acid etacrynic acidethamivan etamivanethamsylate etamsylateethebenecid etebenecidethinyloestradiol ethinylestradiolethoglucid etoglucidethopropazine profenamineethosalamide etosalamideethybenztropine etybenzatropineethyloestrenol ethylestrenolethynodiol etynodiol3
etifoxin etifoxinefanthridone fantridone
3this name is only a proposed INN but the change has been madefor conformity with other names in the relevant series
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Change: To:fenclorphos fenchlofosfenethylline fenetyllinefetoxylate fetoxilateflumethasone flumetasonefluopromazine triflupromazineflupenthixol flupentixolflurothyl flurotylgestronol gestonoroneglycalox glucaloxguaiphenesin guaifenesinhalethazole haletazolehalopyramine chloropyramineheptabarbitone heptabarbhexachlorophane hexachlorophenehexamine hippurate methenamine hippuratehexobarbitone hexobarbitalhydroxamethocaine hydroxytetracainehydroxyamphetamine hydroxyamfetaminehydroxyprogesterone hexanoate hydroxyprogesterone caproateindomethacin indometacinicomethasone enbutate icometasone enbutateiodipamide adipiodoneiophendylate iofendylateiothalamic acid iotalamic acidisobuzole glysobuzoleisoetharine isoetarineisometamidium isometamidium chloridelevamphetamine levamfetaminelynoestrenol lynestrenollysuride lisuridemalethamer maletamermeprothixol meprotixolmethadyl acetate acetylmethadolmethallenoestrol methallenestrilmethallibure metalliburemethamphazone metamfazonemetharbitone metharbitalmethenolone metenolonemethetoin metetoinmethimazole thiamazolemethindizate metindizatemethisazone metisazonemethixene metixenemethohexitone methohexitalmethoin mephenytoinmethsuximide mesuximidemethyl cysteine mecysteinemethylphenobarbitone methylphenobarbitalmethyprylone methyprylonmetriphonate metrifonatemetyzoline metizolinemonosulfiram sulfiramnaphthalophos naftalofosnealbarbitone nealbarbital
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Change: To:nitroxynil nitroxinilnorbutrine norbudrinenorethynodrel noretynodrelnoxiptyline noxiptilinenoxythiolin noxytiolinnylestriol nilestrioloctacosactrin tosactideoctaphonium chloride octafonium chlorideoestradiol estradioloestriol estriol5
oestriol sodium succinate estriol sodium succinate5
oestriol succinate estriol succinateoestrone estroneoxethazaine oxetacaineoxyphenisatin oxyphenisatineoxypurinol oxipurinolpentaerythritol tetranitrate pentaerithrityl tetranitratepentobarbitone pentobarbitalpentolinium tartrate pentolonium tartratephanquone phanquinonephenbenicillin fenbenicillinphenbutrazate fenbutrazatephenethicillin pheneticillinphenobarbitone phenobarbitalphenoxypropazine fenoxypropazinephenyl aminosalicylate fenamisalphenyramidol fenyramidolphthalylsulphathiazole phthalylsulfathiazolepipazethate pipazetatepipothiazine pipotiazinepolyhexanide polihexanidepolymixin polymixin Bpotassium clorazepate dipotassium clorazepatepotassium menaphthosulphate menadiol potassium sulfatepramoxine pramocainepromethoestrol methestrolpromoxolan promoxolanepronethalol pronetalolproquamezine aminopromazineprothionamide protionamidepsilocybin psilocybinepyrithidium bromide pyritidium bromidequinalbarbitone secobarbitalriboflavine riboflavinrolicypram rolicyprinesalazosulphadimidine salazosulfadimidinesecbutobarbitone secbutobarbitalsissomicin sisomicinsodium calciumedetate sodium calcium edetatesodium cromoglycate sodium cromoglicatesodium diatrizoate sodium amidotrizoatesodium ipodate sodium iopodatesodium ironedetate sodium feredetatesodium picosulphate sodium picosulfate
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Change: To:sorbitan mono-oleate sorbitan oleatesorbitan monolaurate sorbitan lauratesorbitan monopalmitate sorbitan palmitatesorbitan monostearate sorbitan stearatestanolone androstanolonestibocaptate sodium stibocaptatestreptonicozid streptoniazidsuccinylsulphathiazole succinylsulfathiazolesulglycotide sulglicotidesulphacetamide sulfacetamidesulphachlorpyridazine sulfachlorpyridazinesulphadiazine sulfadiazinesulphadimethoxine sulfadimethoxinesulphadimidine sulfadimidinesulphaethidole sulfaethidolesulphaguanidine sulfaguanidinesulphaloxic acid sulfaloxic acidsulphamethizole sulfamethizolesulphamethoxazole sulfamethoxazolesulphamethoxydiazine sulfamethoxydiazinesulphamethoxypyridazine sulfamethoxypyridazinesulphamoxole sulfamoxolesulphaphenazole sulfaphenazolesulphaproxyline sulfaproxylinesulphapyridine sulfapyridinesulphasalazine sulfasalazinesulphasomidine sulfisomidinesulphasomizole sulfasomizolesulphathiazole sulfathiazolesulphathiourea sulfathioureasulphatolamide sulfatolamidesulphaurea sulfacarbamidesulphinpyrazone sulfinpyrazonesulphomyxin sodium sulfomyxin sodiumsulthiame sultiametetracosactrin tetracosactidetetrahydrozoline tetryzolinethiabendazole tiabendazolethiacetazone thioacetazonethialbarbitone thialbarbitalthiazesim tiazesimthiocarlide tiocarlidethioguanine tioguaninethiomesterone tiomesteronethiopentone thiopentalthiothixene tiotixenethioxolone tioxolonetriacetyloleandomycin troleandomycintrimustine trichlormethinetroxidone trimethadionetyformin tiforminurofollitrophin urofollitropinvinbarbitone vinbarbitalvinylbitone vinylbital
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Change: To:viprynium embonate pyrvinium pamoatexanthinol nicotinate xantinol nicotinatexanthocillin xantocillin
List III The following changes apply to names for radical and groups.
Change: To:besylate besilatecamsylate camsilateclosylate closilatecypionate cipionateedisylate edisilateenanthate enantateesylate esilateethylsulphate etilsulfateisethionate isetionatemesylate mesilatemethylsulphate metilsulfatenapadisylate napadisilatenapsylate napsilatetheoclate teoclatetosylate tosilate
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Key to Pronunciation
1. Consonants are given their usual values with the following restrictions:g as in goodh as in hard except in the following combinations:
ch as in childth as in thick
j as in job
2. Vowels are given their usual short values with the exception of thefollowing:
ä as in tame ö as in no
á as in malt ôl as in hole
ar as in far oo as in moon
ë as in seen or as in more
er as in herd ú as in full
eer as in beer ü as in cute
ï as in site ûr as in pure
îr as in fire
3. Stressed syllables are in italics.
Symbols and Abbreviations
� Subject of a monograph in the British or European Pharmacopoeias▼ Subject of a monograph in the British Pharmacopoeia (Veterinary)* Contains additional active constituents¨ For use in veterinary medicine only✧ Discontinued or abandoned substance© Available only on a named-patient basis
BSI British Standards Institution Common NameISO International Standards Organization Common Name
pINN Proposed International Nonproprietary NamerINN Recommended International Nonproprietary NameUSAN United States Adopted Name
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1-1
British Approved Names
Abacavir a·ba·ka·veer{(1S,4R)-4-[2-Amino-6-(cyclopropylamino)-9H-purin-9-yl]cyclopent-2-enyl}methanol; C14H18N6O; 168146-84-7; 1592U89Abacavir Sulphate (2:1)Antiviral
N
N
NH
H2N
N
N
OH
Abafungin a·ba·fun·ginHexahydropyrimidin-2-ylidene{4-[2-(2,4-xylyloxy)phenyl]-1,3-thiazol-2-yl}amine; C21H22N4OS; 129639-79-8; Bay w 6341Antifungal; antibacterial
N
NH S
N N
O
CH3
CH3
H
Abanoquil a·ba·nö·kwil6,7-Dimethoxy-2-(1,2,3,4-tetrahydro-6,7-dimethoxyisoquinolin-2-yl)quinolin-4-ylamine; C22H25N3O4; 90402-40-7Abanoquil Mesilate 118931-00-3; UK-52,046-27Alpha1-adrenoceptor antagonist
N N
NH2
OMe
OMeMeO
MeO
Abciximab ab·siks·i·mabImmunoglobulin G (human-mouse monoclonal c7E3 clone p7E3VHhCg4 Fabfragment anti-human platelet glycoprotein IIb/IIIa complex), disulfide with human-mouse monoclonal c7E3 clone p7E3VkhCk light chain; C2101H3229N551O673S15;143653-53-6; c7E3; REOPRO
Antithrombotic
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1-2Abiraterone a·bi·ra·te·rön
17-(3-Pyridyl)androsta-5,16-dien-3b-ol; C24H31NO; 154229-19-3; CB 7598Abiraterone Acetate CB 7630Suppression of androgen production by inhibition of the 17a-hydroxylase/C17-20 lyase enzymecomplex; treatment of prostatic carcinoma
N
Me
HO
Me
H
H
H
Acadesine a·ka·de·sën5-Amino-1-(b-D-ribofuranosyl)imidazole-4-carboxamide; C9H14N4O5;2627-69-2; GP-1-110-0Platelet aggregation inhibitor
N
N NH2
CONH2
HOCH2
HO OH
O
Acamprosate a·kam·prö·sät3-Acetamidopropane-1-sulfonic acid; C5H11NO4S; 77337-76-9Acamprosate Calcium CAMPRAL
Treatment of alcoholism
N SMe
O
OH
O
OH
Acarbose a·kar·bösO-{4-Amino-4,6-dideoxy-N-[(1S)-(1,4,6/5)-4,5,6-trihydroxy-3-hydroxy-methylcyclohex-2-enyl]-a-D-glucopyranosyl}(1® 4)-O-a-D-glucopyranosyl-(1® 4)-D-glucopyranose; C25H43NO18; 56180-94-0; GLUCOBAYAlpha-glucosidase inhibitor
OO O
N O O
OH OH OH OHOH
CH2OHCH2OHCH3CH2OH
HO
OH OH OHOH
H
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1-3Acebutolol a·së·bü·to·lol
(2RS)-3¢-Acetyl-4¢-(2-hydroxy-3-isopropylaminopropoxy)butyranilide;C18H28N2O4; 37517-30-9�Acebutolol Hydrochloride 34381-68-5; SECADREX*; SECTRALBeta-adrenoceptor antagonist
O NHPr iOHH
O
CH3NH
H3C
O
and enantiomer
Aceclofenac a·së·klö·fe·nak[2-(2,6-Dichloroanilino)phenyl]acetoxyacetic acid; C16H13Cl2NO4;89796-99-6; PRESERVEXAnalgesic; anti-inflammatory
HN
Cl
Cl O
O
COOH
Acedapsone a·së·dap·sönBis(4-acetamidophenyl) sulfone; C16H16N2O4S; 77-46-3; CI 556Antileprotic
SOO
AcHN NHAc
Acefluranol a·së·flûr·ra·nol(1) (1RS,2SR)-4,4¢-Diacetoxy-5,5¢-difluoro-(1-ethyl-2-methylethylene)di-m-phenylene diacetate; (2) (aRS,a¢SR)-a-ethyl-5,5¢-difluoro-a¢-methylbibenzyl-3,3¢,4,4¢-tetrayl tetra-acetate; C25H26F2O8; 80595-73-9; BX 591Antioestrogen
MeH
H Et
F
OAc
OAc
F
AcO
AcO
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1-4Acefylline Piperazine (acepifylline) a·si·fi·lën pi·pe·ra·zën
Piperazine bis(theophyllin-7-ylacetate); (C9H10N4O4)2·C4H10N2; 18428-63-2Bronchodilator
,HN NHMeN
N
N
N
O
O
Me
COOH
2
Acemetacin a·së·me·ta·sinO-(1-p-Chlorobenzoyl-5-methoxy-2-methylindol-3-ylacetyl)glycollic acid;C21H18ClNO6; 53164-05-9; EMFLEXAnalgesic; anti-inflammatory
N
O
Cl
OMe
Me
O COOH
O
�Acenocoumarol / Nicoumalone a·së·nö·koo·ma·rol/nï·koo·ma·lön4-Hydroxy-3-(1-p-nitrophenyl-3-oxobutyl)coumarin; C19H15NO6; 152-72-7;SINTHROMEAnticoagulant
O
OH
NO2
CH3
O
H
O
and enantiomer
Acepifylline see Acefylline Piperazine
Acepromazine a·së·prö·ma·zën10-(3-Dimethylaminopropyl)phenothiazin-2-yl methyl ketone; C19H22N2OS; 61-00-7; ACP; ¨̈̈̈̈BK ACE�Acepromazine Maleate 3598-37-6; ¨̈̈̈̈BERKACE; ¨̈̈̈̈BK ACE; ¨̈̈̈̈ORALJECTSEDAZINE; ¨ ¨ ¨ ¨ ¨IMMOBILON*Antipsychotic
N
S
NMe2
O
CH3
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1-5Acesulfame a·së·sul·fäm
6-Methyl-1,2,3-oxathiazin-4(3H)-one 2,2-dioxide; C4H5NO4S; 33665-90-6;Acesulfame Potassium HOE 095K; H73 3293Sweetening agent
NH
SO2O
O
Me
�Acetarsol3-Acetamido-4-hydroxyphenylarsonic acid; C8H10AsNO5; 97-44-9
OH
NHAc
AsO(OH)2
�Acetazolamide a·së·ta·zo·la·mïdN-(5-Sulfamoyl-1,3,4-thiadiazol-2-yl)acetamide; C4H6N4O3S2; 59-66-5; DIAMOX
Carbonic anhydrase inhibitor
N N
S NHAcSOO
H2N
Acetohexamide a·së·tö·heks·a·mïd 1-(4-Acetylphenylsulfonyl)-3-cyclohexylurea;C15H20N2O4S; 968-81-0Hypoglycaemic
SN N
H3C
O
OOO
H H
Acetomenaphthone a·së·tö·me·naf·thön2-Methyl-1,4-naphthylene diacetate; C15H14O4; 573-20-6; KETOVITE*Vitamin K analogue
OAc
Me
OAc
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1-6�Acetorphine
(1) (-)-(5R,6R,7R,14R)-4,5-Epoxy-7-[(1R)-1-hydroxy-1-methylbutyl]-6-methoxy-9a-methyl-6,14-ethenomorphinan-3-yl acetate; (2)(6R,7R,14R)-3-O-acetyl-7,8-dihydro-7-[(1R)-1-hydroxy-1-methylbutyl]-6-O-methyl-6,14-endo-ethenomorphine; C27H35NO5; 25333-77-1
NMe
O
AcO
MeOHMe
HO CH3
H
Acetylcholine Chloride a·së·tïl·kö·lën2-Acetoxyethyltrimethylammonium chloride; C7H16ClNO2; 60-31-1; MIOCHOL*Cholinergic
�Acetylcysteine a·së·tïl·sis·tänN-Acetyl-L-cysteine; C5H9NO3S; 616-91-1; ILUBE*; PARVOLEX
Mucolytic; antidote to paracetamol poisoning
COOH
NHAcH
HS
Acetylmethadol (methadyl acetate) a.cë.tïl.me.tha.dol4-Dimethylamino-1-ethyl-2,2-diphenylpentyl acetate; C23H31NO2; 509-74-0Opioid analgesic
NMe2
H Me
H3COAcH
mixture of stereoisomers
* *
Acexamic Acid a·seks·a·mik a·sid6-Acetamidohexanoic acid; C8H15NO3; 57-08-9�Zinc Acexamate 70020-71-2Treatment of peptic ulcers
H3C N COOH
O
H
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1-7�Aciclovir ä·sï·klö·veer
(1) 2-Amino-9-(2-hydroxyethoxymethyl)-9H-purin-6(1H)-one;(2) 9-(2-hydroxyethoxymethyl)guanine; acyclovir; C8H11N5O3; 59277-89-3;HERPETAD; VIROVIR; ZOVIRAXAntiviral
N
N
N
O
HN
H2N
OOH
Acinitrazole see Aminitrozole
Acipimox ä·sï·pi·moks5-Methylpyrazine-2-carboxylic acid 4-oxide; C6H6N2O3; 51037-30-0; OLBETAMHypolipidaemic
N
N
o
COOH
Me
Acitretin ä·si·tre·tin(1) (2E,4E,6E,8E)-9-(4-Methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetraenoic acid; (2) 3-methoxy-15-j-caroten-15-oic acid; C21H26O3; 55079-83-9; NEOTIGASON
Antipsoriatic
COOH
Me
Me
MeMeO
Me Me
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1-8Aclarubicin a·kla·roo·bi·sin
Methyl (1R,2R,4S)-4-(O-{2,6-dideoxy-4-O-[(2R,6S)-tetrahydro-6-methyl-5-oxopyran-2-yl}a-L-lyxo-hexopyranosyl}(1® 4)-2,3,6-trideoxy-3-dimethylamino-L-lyxo-hexopyranosyloxy)-2-ethyl-1,2,3,4,6,11-hexahydro-2,5,7-trihydroxy-6,11-dioxonaphthacene-1-carboxylate; C42H53NO15;57576-44-0Aclarubicin Hydrochloride ACLACINCytotoxic
O
MeO
O
OOH OH
Et
H
COOMe
OH
O
NMe2
OMe
O
O
OHO
Me
Aclatonium Napadisilate ak·la·tö·në·um na·pa·dï·si·lätBis[2-(O-acetyllactoyloxy)ethyltrimethylammonium naphthalene-1,5-disulfonate; C30H46N2O14S2; 55077-30-0; SKF 100916-JCholinergic
Me3NO
O Me
O
Me O
+
SO3_
SO3_
2
Acrivastine a·kri·vas·tën(E)-3-{6-[(E)-3-Pyrrolidin-1-yl-1-p-tolylprop-1-enyl]-2-pyridyl}acrylic acid;C22H24N2O2; 87848-99-5; SEMPREXHistamine H1-receptor antagonist
N
H
N
H3C
COOH
Acrosoxacin see Rosoxacin
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1-9�Actaplanin
Glycopeptide antibiotic obtained from cultures of Actinoplanes strain ATCC 23342,or the same substance produced by any other means; 37305-75-2
Actinomycin ak·ti·nö·mï·sinAntimicrobial chromopeptolides with antitumour activity produced by Streptomycesantibioticus and S· chrysomallus; cactinomycin (rINN; USAN) is actinomycin C;8052-16-2; dactinomycin (rINN; USAN) is actinomycin D; 50-76-0; COSMEGENLYOVACCytotoxic
Activated Prothrombin Complex (BAN)A preparation from human plasma containing factor VIII inhibitorby-passing activity
Adapalene a·da·pa·lën(1) 6-[4-Methoxy-3-(tricyclo[3.3.1.13,7]dec-1-yl)phenyl-2-naphthoic acid; (2) 6-[3-(1-adamantyl)-4-methoxyphenyl]-2-naphthoic acid; C28H28O3; 106685-40-9;DIFFERINTreatment of acne
COOH
MeO
Adefovir a·de·fö·veer[2-(6-Amino-9H-purin-9-yl)ethoxymethyl]phosphonic acid; C8H12N5O4P; 106941-25-7Adefovir Dipivoxil 142340-99-6Antiviral
N
N
N
N
NH2
O P
O
OH
OH
Adenosine (BAN) a·den·ö·sën(R)-1-(6-Amino-9H-purin-9-yl)-1-deoxy-D-ribofuranose; C10H13N5O4;58-61-7; ADENOCOR; ADENOSCAN; VIVIOPTAL
Antiarrhythmic
O
OH OH
HO
N
NN
N
NH2
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1-10�Adenosine Phosphate
Adenosine 5¢-(dihydrogen phosphate); C10H14N5O7P; 61-19-8; adenosinemonophosphate; AMPNutrient
O
N
NN
N
OH OH
NH2
OHO
OH
O
P
�Adicillin(6R)-6-(D-5-Amino-5-carboxyvaleramido)penicillanic acid; penicillin N;C14H21N3O6S; 525-94-0
HN
NOO
S
H COOH
Me
Me
H HHOOC
NH2H
Adinazolam a·di·nä·zö·lam8-Chloro-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]benzodiazepin-1-ylmethyldimethylamine; C19H18ClN5; 37115-32-5; U-41123Adinazolam Mesilate 57938-82-6; U-41123FAntidepressant
N
N
NN
Me2N
Cl
Adipiodone (iodipamide) a·di·pï·ö·dön3,3¢-Adipoyldiaminobis(2,4,6-tri-iodobenzoic acid); C20H14I6N2O6; 606-17-7Adipiodone Meglumine 3521-84-4; BILIGRAFIN; ENDOGRAFINContrast medium
COOH
I
I
I
NH
O
[CH2]4
COOH
I
I
I
NH
O
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1-11�Adrenaline/Epinephrine a·dre·na·lën/e·pi·ne·frën
(R)-1-(3,4-Dihydroxyphenyl)-2-methylaminoethanol; C9H13NO3; 51-43-4;ACCUSITE*; EPIFRIN; EPPY; GANDA*; ISOPTO EPINAL; EPIPEN; MARCAINE WITHADRENALINE*; MEDIHALER-EPI; SIMPLENE; ¨̈̈̈̈WILLCAIN*; XYLOCAINE*�Adrenaline Acid Tartrate/Epinephrine Acid Tartrate epinephrine bitartrate(USP); 51-42-3; MEDIHALER EPI; ¨̈̈̈̈LOCOVETIC*Alpha- and beta-adrenoceptor agonist
NHMeOHH
HO
HO
Aklomide ak·lö·mïd2-Chloro-4-nitrobenzamide; C7H5ClN2O3; 3011-89-0Coccidiostat
CONH2
Cl
NO2
Alafosfalin a·la·fos·fa·lin(1R)-L-(l-Alaninamido)ethylphosphonic acid; C5H13N2O4P; 60668-24-8;Ro 03-7008Antibacterial
P
O
OH
OHHN
H2NHMeO
MeH
Albendazole al·ben·da·zôlMethyl 5-propylthio-1H-benzimidazol-2-ylcarbamate; C12H15N3O2S;54965-21-8; ¨̈̈̈̈ALLVERM; ESKAZOLE; ¨̈̈̈̈PROFTRIL; ¨̈̈̈̈VALBAZENAnthelmintic
N
N NHCOOMe
SH3C
H
Albendazole OxideMethyl 5-(propylsulfinyl)benzimidazol-2-ylcarbamate; albendazole sulfoxide;C12H15N3O3S; 54029-12-8; ̈̈̈̈̈ BENTALAnthelmintic (veterinary)
N
HN NHCOOMe
SH3C
O
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1-12Alclofenac al·klö·fe·nak
(4-Allyloxy-3-chlorophenyl)acetic acid; C11H11ClO3; 22131-79-9Analgesic; anti-inflammatory
COOHCl
OH2C
Alclometasone al·klö·me·ta·sön7a-Chloro-11b,17a,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione;C28H37ClO7; 67452-97-5Alclometasone Dipropionate 66734-13-2; ¨MODRASONECorticosteroid
O
Me
H
HO
H
H
Me
Me OHO
OH
Cl
�Alcuronium Chloride al·kûr·rö·në·umN,N-Diallyldinortoxiferinium dichloride; C44H50Cl2N4O2; 15180-03-7Neuromuscular blocker
N
N
N
NH2C
CH2
HH
HH
HH
HO
OH
+
+
2Cl_
Aldesleukin al·des·loo·kinDes-alanyl-1, serine-125 human interleukin-2; recombinant interleukin-2;C690H1115N177O203S6; 110942-02-4; PROLEUKINTreatment of metastatic renal cell carcinoma
aldesleukin has the following amino acid sequence:
PTSSSTKKTG LQLEHLLLDL QMILNGINNY
KNPKLTRMLT FKFYMPKKAT ELKHLQCLEE
ELKPLEEVLN LAQSKNFHLR PRDLISNINV
IVLELKGSET TFMCEYADET ATIVEFLNRW
ITFSQSIIST LT
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1-13Aldosterone al·dö·steer·rön
11,18-Hemiacetal of 11b,21-dihydroxy-3,20-dioxopregn-4-en-18-al; C21H28O5; 52-39-1Corticosteroid
O
Me
H
H
H
OHO
OH
O
Alemtuzumab a·lem·tü·zü·mabImmunoglobulin G1 (human-rat monoclonal CAMPATH-1H g1-chain anti-humanantigen CD52), disulfide with human-rat monoclonal CAMPATH-1H light chaindimer; 216503-57-0Immunomodulator
Alendronic Acid a·len·dro·nik4-Amino-1-hydroxybutane-1,1-diylbis(phosphonic acid); C4H13NO7P2;66376-36-1Alendronate Sodium 121268-17-5; FOSAMAXInhibition of bone resorption
P
O
OH
OHP
O
OH
HO C
OH
NH2
Alexitol Sodium a·leks·i·tolSodium poly(hydroxyaluminium) carbonate—hexitol complex 66813-51-2; ACTALAntacid
�Alfacalcidol al·fa·kal·si·dol9,10-Secocholesta-5,7,10(19)-triene-1a,3b-diol; 1a-hydroxycholecalciferol;1a-hydroxyvitamin D3; 1a-OHD3; C27H44O2; 41294-56-8; ALFA-D;ONE-ALPHA; ¨̈̈̈̈ VETALPHAVitamin D analogue
Me
Me
H
HO
H
HMe
MeH
HO H2C
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1-14Alfadolone (alphadolone) al·fa·do·lön
3a,21-Dihydroxy-5a-pregnane-11,20-dione; C21H32O4; 14107-37-0�Alfadolone Acetate 23930-37-2; ¨̈̈̈̈ SAFFAN*Anaesthetic
Me
HMe
OOH
HO
HOH
HH
Alfaprostol al·fa·pros·tolMethyl (Z)-7-{(1R,2S,3R,5S)-2-[(3S)-5-cyclohexyl-3-hydroxypent-1-ynyl]-3,5-dihydroxycyclopentyl}hept-5-enoate; C24H38O5; 74176-31-1;¨̈̈̈̈ ALPHACEPTProstanoid luteolytic (veterinary)
HO
HO
COOMe
H OH
H
H
�Alfaxalone (alphaxalone) al·faks·a·lön3a-Hydroxy-5a-pregnane-11,20-dione; C21H32O3; 23930-19-0; ¨̈̈̈̈ SAFFAN*Anaesthetic
Me
HMe
H H
CH3O
H
H
O
HHO
Alfentanil al·fen·ta·nilN-{1-[2-(4-Ethyl-5-oxo-2-tetrazolin-1-yl)ethyl]-4-(methoxymethyl)-4-piperidyl}propionanilide; C21H32N6O3; 71195-58-9Alfentanil Hydrochloride 70879-28-6; 69049-06-5; RAPIFENOpioid analgesic
N
NN
N
OMe
O N
NH3C O
Et
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1-15Alfuzosin al·fü·zö·sin
N-{3-[4-Amino-6,7-dimethoxyquinazolin-2-yl(methyl)amino]propyl}tetrahydro-2-furamide; C19H27N5O4; 81403-80-7; SL 77 499-10�Alfuzosin Hydrochloride 81403-68-1; XATRALAlpha-adrenoceptor antagonist
O
O
HN
Me
N
NH2
MeO
MeO
N
N
Algestone Acetonide (INNM) al·jes·tön a·se·to·nïd16a,17a-Isopropylidenedioxypregn-4-ene-3,20-dione; C24H34O4;595-77-7Progestogen
O
O Me
Me
O
Me
MeCH3O
HH
H
�Alginic Acid al·ji·nikA polyuronic acid composed of residues of D-mannuronic and L-guluronic acidsobtained chiefly by extraction of algae belonging to the Phaeophyceae; mainlyspecies of Laminaria; 9005-32-7; ALGITEC*; GASTROCOTE*; GAVISCON*;PYROGASTRONE*; TOPAL*Pharmaceutical aid
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1-16Alglucerase al·gloo·se·räs
Macrophage-targeted b-glucocerebrosidase; monomeric glycoprotein of497 amino acids with glycosylation making up about 6% of the molecule;143003-46-7; CEREDASEUsed in treatment of Gaucher's disease (enzyme replacement; b-glucocerebrosidase)
alglucerase has the following amino acid sequence:
ARPCIPKSFG YSSVVCVCNA TYCDSFDPPT
FPALGTFSRY ESTRSGRRME LSMGPIQANH
TGTGLLLTLQ PEQKFQKVKG FGGAMTDAAA
LNILALSPPA QNLLLKSYFS EEGIGYNIIR
VPMASCDFSI RTYTYADTPD DFQLHNFSLP
EEDTKLKIPL IHRALQLAQR PVSLLASPWT
SPTWLKTNGA VNGKGSLKGQ PGDIYHQTWA
RYFVKFLDAY AEHKLQFWAV TAENEPSAGL
LSGYPFQCLG FTPEHQRDFI ARDLGPTLAN
STHHNVRLLM LDDQRLLLPH WAKVVLTDPE
AAKYVHGIAV HWYLDFLAPA KATLGETHRL
FPNTMLFASE ACVGSKFWEQ SVRLGSWDRG
MQYSHSIITN LLYHVVGWTD WNLALNPEGG
PNWVRNFVDS PIIVDITKDT FYKQPMFYHL
GHFSKFIPEG SGRVGLVASQ KNDLDAVALM
HPDGSAVVVV LNRSSKDVPL TIKDPAVGFL
EYISPGYSIH TYLWRRQ
Alimemazine / Trimeprazine a·li·mem·a·zën/trï·me·pra·zënDimethyl(2-methyl-3-phenothiazin-10-ylpropyl)amine; (C18H22N2S)2; 84-96-8�Alimemazine Tartrate / Trimeprazine Tartrate 4330-99-8; VALLERGANHistamine H1-receptor antagonist
N
S
NMe2H Me
and enantiomer
Alinidine a·li·ni·dënN-Allyl-2,6-dichloro-N-(2-imidazolin-2-yl)aniline; C12H13Cl2N3;33178-86-8Alinidine Hydrobromide St-567-BRAntiarrhythmic
ClNH
NN
ClH2C
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1-17Alipamide a·li·pa·mïd
4-Chloro-N¢,N¢-dimethyl-3-sulfamoylbenzohydrazide; C9H12ClN3O3S;3184-59-6; CI-546Diuretic
Cl
SO2NH2
NNMe2
O
H
Alitretinoin a·li·tre·ti·nö·in(2E,4E,6Z,8E)-3,7-Dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenoic acid; 9-cis-retinoic acid; C20H28O2; 5300-03-8Antineoplasti
COOH
Me Me
Me
Me
Me
�Allantoin (BAN) a·lan·tö·in2,5-Dioxoimidazolidin-4-ylurea; C4H6N4O3; 97-59-6; ACTINAC*; ALPHOSYL*; ALPHOSYL
HC*; DERMALEX*Treatment of skin disorders
NH
N O
O
NH2N
O
HH
�Alletorphine(1) (2R)-2-[(-)-(5R,6R,7R,14R)-17-Allyl-4,5-epoxy-3-hydroxy-6-methoxy-6,14-ethenomorphinan-7-yl]pentan-2-ol; (2) (6R,7R,14R)-17-allyl-7,8-dihydro-7-[(1R)-1-hydroxy-1-methylbutyl]-6-O-methyl-6,14-etheno-17-normorphine; N-allylnoretorphine; C27H35NO4; 23758-80-7
N
O
HO
MeOHMe
HO CH3
CH2
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1-18Allomethadione (aloxidone) a·loks·i·dön
(±)-3-Allyl-5-methyl-1,3-oxazolidine-2,4-dione; C7H9NO3; 526-35-2Anticonvulsant
NO
O
CH2
OMe
and enantiomer
*
�Allopurinol a·lö·pûr·ri·nol1H-Pyrazolo[3,4-d]pyrimidin-4-ol; C5H4N4O; 315-30-0; CAPLENAL; COSURIC;LEDERPUR; ZYLORICPrevention and treatment of gout
N NN
HN
O
N
N NN
OH
HH
�Allylestrenol (allyloestrenol) a·lïl·ës·tre·nol17a-Allylestr-4-en-17b-ol; C21H32O; 432-60-0Progestogen
OHH
H H
CH2Me
Allylprodine a·lïl·prö·dën(3S,4R)-3-Allyl-1-methyl-4-phenyl-4-piperidyl propionate; C18H25NO2; 25384-17-2Opioid analgesic
N
OCOEt
Me
CH2
Almagate al·ma·gätAluminium trimagnesium carbonate heptahydroxide dihydrate;(AlMg3(CO3)(OH)7,2H2O; 66827-12-1Antacid
�Almasilate al·ma·si·lätAluminium magnesium silicate hydrate (artificial); Al2O3·MgO·2SiO2,xH2O; 50958-44-6Antacid
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1-19Almitrine al·mi·trën
N,N¢-Diallyl-6-[4-(4,4¢-difluorobenzhydryl)piperazin-1-yl]-1,3,5-triazine-2,4-diyldiamine; C26H29F2O7; 27469-53-0Respiratory stimulant
N NN
NN
NCH2
HNCH2
F
F
H
Almotriptan al·mo·trip·tanDimethyl{2-[5-(pyrrolidin-1-ylsulfonylmethyl)indol-3-yl]ethyl}amine;C17H25N3O2S; 154323-57-6; LAS 31416 5HT1D-Serotonin receptor agonist
HN
NS
OO
NMe2
Almurtide al·mür·tidN2-[(2-Acetamido-2-deoxy-D-glucopyranos-3-O-yl)acetyl-L-alanyl]-D-glutamic acid 1-amide; C18H30N4O11; NorMDPAlmurtide Sodium 60355-77-3Immunostimulant
O
CH2OH
NHCOMe
O
HN
NH
COOH
O Me H
O CONH2H
HOOH
Alniditan al·ni·di·tan(R)-N-Chroman-2-ylmethyl-N¢-(1,4,5,6-tetrahydropyrimidin-2-yl)propane-1,3-diamine; C17H26N4O; 152317-89-0; R91274Alniditan Dihydrochloride5HT1D-receptor agonist
ON N
H
N
HN
H H
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1-20�Aloin (BAN) a·lö·in
10-b-D-Glucopyranosyl-1,8-dihydroxy-3-hydroxymethyl-9(10H)-anthrone;barbaloin; C21H22O9; 5133-19-7; ALOPHEN
Laxative
O
OHHO
HO
OH
OH O OH
CH2OH
Alosetron a·lö·se·tron2,3,4,5-Tetrahydro-5-methyl-2-(5-methylimidazol-4-ylmethyl)-pyrido[4,3-b]indol-1-one; C17H18N4O; 122852-42-0; GR 68755XAlosetron Hydrochloride 122852-69-1; GR 68755CSerotonin 5HT3-receptor antagonist
MeO
Me
NHN
N
N
Aloxidone see Allomethadione
�Aloxiprin a·loks·i·prinPolymeric condensation product of aluminium oxide and O-acetylsalicylic acid;9014-67-9; PALAPRINAnalgesic; anti-inflammatory
Alphacetylmethadol al·fa·së·tïl·me·tha·dol(1R,4R)-4-Dimethylamino-1-ethyl-2,2-diphenylpentyl acetate; C23H31NO2; 17199-58-5Opioid analgesic
HMe2N
H3CH OAc
CH3
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1-21Alpha-Cypermethrin� (BAN) al·fa·sï·per·më·thrin
(SR)-a-Cyano-3-phenoxybenzyl (1RS,3RS)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; C22H19Cl2NO3; 67375-30-8;¨̈̈̈̈DY-SECT; ¨̈̈̈̈RENEGADEInsecticide
and enantiomer
H CN
O
O
Me
Me
H
Cl
Cl
H H
O
Alphadolone see Alfadolone
Alphameprodine al·fa·me·prö·dën(3S,4R)-3-Ethyl-1-methyl-4-phenyl-4-piperidyl propionate; C17H25NO2;468-51-9Opioid analgesic
NMe
OOCEt
HEt
Alphamethadol al·fa·me·tha·dol(3R,6R)-6-Dimethylamino-4,4-diphenylheptan-3-ol; C21H29NO;17199-54-1Opioid analgesic
HMe2N
H3CH OH
CH3
�Alphaprodine al·fa·prö·dën(3S,4R)-1,3-Dimethyl-4-phenyl-4-piperidyl propionate; C16H23NO2;77-20-3Alphaprodine Hydrochloride 14405-05-1Opioid analgesic
NMe
OOCEt
HMe
Alphaxalone see Alfaxalone
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1-22�Alpidem al·pi·dem
2-(6-Chloro-2-p-chlorophenylimidazo[1,2-a]pyridin-3-yl)-N,N-dipropylacetamide;C21H23Cl2N3O; 82626-01-5; SL 80·0342-00Anxiolytic
Cl
Cl
N
N
NPrn2O
Alprazolam al·prä·zö·lam8-Chloro-1-methyl-6-phenyl-4H-[1,2,4]triazolo[4,3-a][1,4]-benzodiazepine;C17H13ClN4; 28981-97-7; XANAXAlprazolam Mesilate 57938-82-6; U-41,123Anxiolytic
N
NCl
NNMe
Alprenolol al·pre·no·lol1-(2-Allylphenoxy)-3-isopropylaminopropan-2-ol; C15H23NO2; 13655-52-2�Alprenolol Benzoate�Alprenolol Hydrochloride 13707-88-5Beta-adrenoceptor antagonist
O NHPri
OHH
CH2
and enantiomer
Alprostadil al·prost·a·dil(1) 7-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl}heptanoic acid; (2) (13E)-(11R,15S)-11,15-dihydroxy-9-oxoprost-13-enoic acid; C20H34O5; 745-65-3; ¨̈̈̈̈CAVERJECT; MUSE; PROSTIN VRProstanoid vasodilator
HO H
COOHO
CH3
H OH
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1-23Alprostadil Alfadex (INNM) al·prost·a·dil al·fa·deks
(1) a-Cyclodextrin¾ 7-{(1R,2R,3R)-3-hydroxy-2-[(E)-(3S)-3-hydroxyoct-1-enyl]-5-oxo-cyclopentyl}heptanoic acid; (2) cyclomaltohexaose¾ (13E)-(11R,15S)-11,15-dihydroxy-9-oxoprost-13-enoic acid; C20H34O5·x[C36H60O30];PGE1 a-CD; VIRIDALVasodilator
Alteplase al·te·pläsRecombinant tissue-type plasminogen activator produced by a Chinese hamsterovary (CHO) cell line transformed with the human t-PA gene;a glycosylated protein of 527 residues having the amino acid sequence of humantissue plasminogen activator; C2736H4174N914O824S45 (non-glycosylated protein);105857-23-6; ACTILYSE
Fibrinolytic
For labelling purposes the name carries an approved code, in parentheses and inlower case letters, indicative of the method of production·The following code is approved:
(rch) produced from genetically engineered Chinese hamster ovary cells
Alteplase has the following amino acid sequence:
SYQVICRDEK TQMIYQQHQS WLRPVLRSNR
VEYCWCNSGR AQCHSVPVKS CSEPRCFNGG
TCQQALYFSD FVCQCPEGFA GKCCEIDTRA
TCYEDQGISY RGTWSTAESG AECTNWNSSA
LAQKPYSGRR PDAIRLGLGN HNYCRNPDRD
SKPWCYVFKA GKYSSEFCST PACSEGNSDC
YFGNGSAYRG THSLTESGAS CLPWNSMILI
GKVYTAQNPS AQALGLGKHN YCRNPDGDAK
PWCHVLKNRR LTWEYCDVPS CSTCGLRQYS
QPQFR
IKGGLFADIA SHPWQAAIFA KHRRSPGERF
LCGGILISSC WILSAAHCFQ ERFPPHHLTV
ILGRTYRVVP GEEEQKFEVE KYIVHKEFDD
DTYDNDIALL QLKSDSSRCA QESSVVRTVC
LPPADLQLPD WTECELSGYG KHEALSPFYS
ERLKEAHVRL YPSSRCTSQH LLNRTVTDNM
LCAGDTRSGG PQANLHDACQ GDSGGPLVCL
NDGRMTLVGI ISWGLGCGQK DVPGVYTKVT
NYLDWIRDNM RP
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1-24Altrenogest al·tre·nö·jest
(1) 17a-Allyl-17b-hydroxy-19-norandrosta-4,9,11-trien-3-one;(2)17b-hydroxy-19,21,24-trinorchola-4,9,11,22-tetraen-3-one; C21H26O2;850-52-2; ̈ REGUMATEProgestogen
O
MeOH
CH2
Altretamine al·tre·ta·mënN2,N2,N4,N4,N6,N6-Hexamethyl-1,3,5-triazine-2,4,6-triamine; C9Hl8N6;645-05-6; NSC-13875Antineoplastic
N
N
N
Me2N NMe2
NMe2
Aluminium Clofibrate klö·fi·brätBis[2-(4-chlorophenoxy)-2-methylpropionato]hydroxoaluminium; C20H21AlCl2O7;14613-01-5Treatment of arterioscleroris
Cl
OO
Me Me
O
Al
OH
OO
O
Me MeCl
Alverine al·ve·rënEthylbis(3-phenylpropyl)amine; C20H27N; 150-59-4Alverine Citrate 5560-59-8; ALVERCOL; SPASMONALAntispasmodic
N
Et
Amafolone a·ma·fo·lön3a-Amino-2b-hydroxy-5a-androstan-17-one; C19H31NO2; 50588-47-1Amafolone Hydrochloride Org 6001Antiarrhythmic
H H
HMe
Me O
H2N
HO
H
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1-25Amantadine a·man·ta·dën
Tricyclo[3.3.1.1.3,7]dec-1-ylamine; 1-adamantanamine; C10H17N;768-94-5�Amantadine Hydrochloride 665-66-7; SYMMETRELDopaminergic
NH2
Ambazone am·ba·zön6-Amidinohydrazonocyclohexa-1,4-dien-3-one thiosemicarbazone; C8H11N7S;6011-12-7Anti-infective
NNH
N
HN
NH2
H2N
S
NH
Ambenonium Chloride am·be·nö·në·umN,N¢-Oxalylbis(N-2-aminoethyl-N-2-chlorobenzyldiethylammonium) dichloride;C28H42Cl4N4O2; 115-79-7Anticholinesterase
H
HN
NN
N
O
O EtEt
EtEt Cl
Cl2Cl −+
+
Ambenoxan am·be·noks·an2,3 Dihydro-1,4-benzodioxin-2-ylmethyl[2-(2-methoxyethoxy)ethyl]amine;C14H21NO4; 2455-84-7Muscle relaxant
ON
OOMe
OH
Ambicromil am·bï·krö·mil4,6-Dioxo-10-propyl-4H,6H-pyrano[3,2-g]chromene-2,8-dicarboxylic acid;C17H12O8; 58805-38-2Ambicromil Calcium probicromil calcium (USAN); 71144-97-3Prophylaxis of allergic conditions
O O
O
Prn
O
COOHHOOC
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1-26Ambucetamide am·bü·se·ta·mïd
(±)-2-Dibutylamino-2-(4-methoxyphenyl)acetamide; C17H28N2O2; 519-88-0Antispasmodic
MeO
CONH2
NBun2H
and enantiomer
Ambuside am·bü·sïd5-Allylsulfamoyl-2-chloro-4-(3-hydroxybut-2-enylideneamino)benzenesulfonamide;C13H16ClN3O5S; 3754-19-6Diuretic
H3C
HOCHCH N
CH2
Cl
SO2NH2
SO2NHCH2CH
Ambutonium Bromide����� am·bü·tö·në·um(3-Carbamoyl-3,3-diphenylpropyl)ethyldimethylammonium bromide;C20H27BrN2O;115-51-5; ALUDROX SA*Anticholinergic
NMe2
EtCONH2
Br−+
Amcinonide am·si·no·nïd16a,17a-Cyclopentylidenedioxy-9a-fluoro-11b-hydroxy-3,20-dioxopregna-1,4-dien-21-yl acetate; C28H35FO7; 51022-69-6; CL 34699Corticosteroid
O
HO
F H
HMe
Me
O
O
OAcO
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1-27Ameltolide a·mel·to·lïd
4-Aminobenzo-2¢,6¢-xylidide; C15H16N2O; 787-93-9; LY201116Anticonvulsant
N
H2N
O
Me
Me
H
Ametazole a·me·ta·zôl2-(Pyrazol-3-yl)ethylamine; betazole (pINN); C5H9N3; 105-20-4Ametazole Hydrochloride 138-92-1Diagnostic aid
NN
NH2
H
Amethocaine see Tetracaine
Amfebutamone (bupropion) am·fë·bü·ta·mön2-(tert-Butylamino)-3¢-chloropropiophenone; C13H18ClNO; 34911-55-2Amfebutamone Hydrochloride 31677-93-7; BW 323Antidepressant
CH3
O
H NHBut
Cl
and enantiomer
Amfecloral am·fe·klor·rala-Methylphenethyl(2,2,2-trichloroethylidene)amine; C11H12Cl3N;5581-35-1Appetite suppressant
NCHCCl3
H Me
and enantiomer
Amfenac am·fe·nak(2-Amino-3-benzoylphenyl)acetic acid; C15H13NO3; 51579-82-9Amfenac Sodium 61618-27-7; AHR 5850Analgesic; anti-inflammatory
O NH2
COOH
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1-28Amfetamine (amphetamine) am·fe·ta·mën
(R,S)-a-Methylphenethylamine; C9H13N; 300-62-9�Amfetamine Sulphate 60-13-9Central nervous system stimulant
NH2
MeH
and enantiomer
Amfonelic Acid am·fö·ne·lik7-Benzyl-1-ethyl-1,4-dihydro-4-oxo-1,8-naphthyridine-3-carboxylic acid;C18H16N2O3; 15180-02-6Central nervous system stimulant
N N
O
Et
COOH
Amicarbalide a·mi·kar·ba·lïd(1) 1,3-Bis(3-amidinophenyl)urea; (2) 3,3¢-diamidinocarbanilide; C15H16N6O; 3459-96-9Amicarbalide Isethionate 3671-72-5Antiprotozoan
N NNH
NH2
HN
NH2
O
HH
Amidantel a·mi·dan·tel4¢-(1-Dimethylaminoethylideneamino)-2-methoxyacetanilide; C13H19N3O2; 49745-00-8Amidantel Hydrochloride BAY d 8815Anthelmintic
NMe2
CH3N
NMeO
O
H
Amidephrine a·mï·de·frën(±)-3¢-(1-Hydroxy-2-methylaminoethyl)methanesulfonanilide; C10H16N2O3S; 1421-68-7Vasoconstrictor; nasal decongestant
SOO
H3CHN NHMe
H OH
and enantiomer
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1-29�Amidotrizoic Acid (diatrizoic acid) a·mï·dö·trï·zö·ik
3,5-Diacetamido-2,4,6-tri-iodobenzoic acid; ; C11H9I3N2O4; 117-96-4MeglumineAmidotrizoate 131-49-7; ANGIOGRAFIN*; GASTROGRAFIN*;UROGRAFIN*�Sodium Amidotrizoate 737-31-5; GASTROGRAFIN*; HYPAQUE; UROGRAFIN*;UROVISION*Contrast medium
COOH
I
I
I
NHAcAcHN
Amifloxacin a·mi·floks·a·sin6-Fluoro-1,4-dihydro-1-methylamino-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid; C16H19FN4O3; 86393-37-5;WIN 49375Amifloxacin Mesilate 88036-80-0; WIN 49375-3Antibacterial
NMe
F
NHMe
COOH
O
NN
Amifostine a·mi·fos·tënS-[2-(3-Aminopropylamino)ethyl] dihydrogen phosphorothioate; C5H15N2O3PS;20537-88-6; ETHYOLChemoprotective and radioprotective agent
P
O
OH
SNH2N
OH
H
�Amikacin a·mi·kä·sin6-O-(3-Amino-3-deoxy-a-D-glucopyranosyl)-4-O-(6-amino-6-deoxy-a-D-glucopyranosyl)-N1-[(2S)-4-amino-2-hydroxybutyryl]-2-deoxy-D-streptamine;C22H43N5O13; 37517-28-5�Amikacin Sulphate 39831-55-5; AMIKINAntibacterial
NH2NH
OH
O
O
HO
NH2O
OH
OH
HO
NH2
O
O
H OH
H2N
HO
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1-30Amiloride a·mi·lor·rïd
N-Amidino-3,5-diamino-6-chloropyrazine-2-carboxamide; C6H8ClN7O; 2609-46-3�Amiloride Hydrochloride 17440-83-4 (dihydrate); 2016-88-8 (anhydrous); AMIL-CO*; BURINEX A*; FRU-CO*; FRUMIL*; FRUSEMEK*; KALTEN*; LASORIDE*;MODUCREN*; MODURET*; MODURETIC*; NAVISPARE*; SYNURETIC*Diuretic
N
N
NH2H2N
ClN NH2
O NH
H
Aminacrine see Aminoacridine
Aminitrozole (acinitrozole) a·mi·nï·tra·zôlN-(5-Nitro-1,3-thiazol-2-yl)acetamide; nithiamide (USAN); C5H5N3O3S; 140-40-9Antiprotozoan
N
SO2N NHAc
Aminoacridine (aminacrine) a·mï·nö·a·kri·dënAcridin-9-ylamine; C13H10N2; 90-45-9Aminoacridine Hydrochloride 134-50-9Anti-infective
N
NH2
Aminocaproic Acid a·mï·nö·ka·prö·ik6-Aminohexanoic acid; C6H13NO2; 60-32-2Inhibitor of fibrinolytic activity
H2N COOH
�Aminoglutethimide a·mï·nö·gloo·te·thi·mïd2-(4-Aminophenyl)-2-ethylglutarimide; C13H16N2O2; 125-84-8; ORIMETENInhibitor of adrenal corticosteroid synthesis
HN
NH2
EtO
O
Aminometradine a·mï·nö·me·tra·dën1-Allyl-6-amino-3-ethylpyrimidine-2,4(1H,3H)-dione; C9H13N3O2;642-44-4Diuretic
N
N OH2N
O
CH2
Et
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1-31�Aminophylline a·mi·no·fi·lën
3,7-Dihydro-1,3-dimethylpurine-2,6(1H)-dione—ethylenediamine(2:1);C16H24N10O4; 317-34-0; AMNIVENT; PECRAM; PHYLLOCONTIN CONTINUSBronchodilator
NMe
Me
O
O
N
N
N
H
NH2
NH2
.
2
Aminopromazine (proquamezine) a·mi·no·pro·ma·zënTetramethyl(1-phenothiazin-10-ylmethyl)ethylenediamine; C19H25N3S; 58-37-7Aminopromazine Fumarate 3688-62-8; ¨MYSPAMOLAntispasmodic
N
S
NMe2H NMe2
and enantiomer
Aminopterin Sodium a·mi·nö·te·rinSodium 4-aminopteroylglutamate; C19H18N8Na2O5; 58602-66-7Cytotoxic
N
N
N
HN
HN
HN
COONa
H2N
O H COONa
NH2
Aminorex a·mi·nor·reks(±)-4,5-Dihydro-5-phenyl-1,3-oxazol-2-ylamine; C9H10N2O; 2207-50-3Appetite suppressant
N
O NH2
and enantiomer
*
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1-32Amiodarone a·mï·ö·da·rön
2-Butylbenzofuran-3-yl 4-(2-diethylaminoethoxy)-3,5-di-iodophenyl ketone;C25H29I2NO3; 1951-25-3�Amiodarone Hydrochloride 19774-82-4; CORDARONE XAntiarrhythmic
O
O
ONEt2
I
I
Bun
Amiphenazole a·mi·fen·a·zôl5-Phenyl-1,3-thiazole-2,4-diyldiamine; C9H9N3S; 490-55-1Central nervous system stimulant
N
S NH2
H2N
Amisometradine a·mï·sö·me·tra·dën6-Amino-3-methyl-1-(2-methylallyl)pyrimidine-2,4(1H,3H)-dione; C9H13N3O2; 550-28-7Diuretic
NMe
NH2N O
CH2
Me
O
Amisulpride a·mi·sul·prïd(RS)-4-Amino-N-[(1-ethylpyrrolidin-2-yl)methyl]-5-(ethylsulfonyl)-o-anisamide;C17H27N3O4S; 71675-85-9; DAN-216; SOLIAN
Dopamine D2/D3-receptor antagonist; treatment of schizophrenia
H
S CH3O O
NH2NEt
O
N
MeO
H
and enantiomer
�Amitraz a·mi·trazMethylbis(2,4-xylyliminomethyl)amine; C19H23N3; 33089-61-1; ¨̈̈̈̈ALUDEX;¨̈̈̈̈TAKTIC; ¨̈̈̈̈TOPLINEAcaricide
N
N
Me
N
Me
Me
Me
Me
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1-33Amitriptyline a·mi·trip·ti·lën
3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)propyldimethylamine;C20H23N; 50-48-6Amitriptyline Embonate 17086-03-2; TRYPTIZOL SYRUP�Amitriptyline Hydrochloride 549-18-8; DOMICAL; ELAVIL; LENTIZOL;TRIPTAFEN*; TRYPTIZOLAntidepressant
NMe2
Amlexanox am·leks·a·noks2-Amino-7-isopropyl-5-oxo-5H-[1]benzopyrano[2,3-b]pyridine-3-carboxylic acid;C16H14N2O4;68302-57-8Anti-allergic
O N NH2
COOHPr i
O
Amlodipine am·lö·di·pën(±)-3-Ethyl 5-methyl 2-(2-aminoethoxymethyl)-4-(2-chlorophenyl)-1,4-dihydro-6-methylpyridine-3,5-dicarboxylate; C20H25ClN2O5; 88150-42-9Amlodipine Maleate 88150-47-4; UK-48340-11Amlodipine Besilate 111470-99-6; ISTINCalcium antagonist
ONH2
Cl
MeOOC COOEt
Me NH
*
and enantiomer
�Amobarbital (amylobarbitone) a·mï·lö·bar·bi·tal5-Ethyl-5-isopentylbarbituric acid; C11H18N2O3; 57-43-2; AMYTAL�Amobarbital Sodium 64-43-7; SODIUM AMYTAL; TUINAL*Hypnotic
NH
N
EtMe
Me O
OOH
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1-34Amodiaquine a·mö·dï·a·kwën
4-(7-Chloro-4-quinolylamino)-2-(diethylaminomethyl)phenol; C20H22ClN3O; 86-42-0Amodiaquine Hydrochloride 6398-98-7Antimalarial
NEt2
OH
N
N
ClH
Amorolfine a·mo·rol·fëncis-4-{(RS)-3-[4-(1,1-Dimethylpropyl)phenyl]-2-methylpropyl}-2,6-dimethylmorpholine; C21H35NO; 78613-35-1Amorolfine Hydrochloride 78613-38-4; LOCERYLAntifungal
O
NH Me
CH3
MeMeMeH
HMe *
and epimer at C*
Amoxapine a·moks·a·pën2-Chloro-11-(piperazin-1-yl)dibenz[b,f][1,4]oxazepine; C17H16ClN3O; 14028-44-5;ASENDISAntidepressant
N
O
N
HN
Cl
Amoxicillin (amoxycillin) a·moks·i·si·lin(6R)-6-(a-D-p-Hydroxyphenylglycylamino)penicillanic acid; C16H19N3O5S; 26787-78-0�Amoxicillin Sodium 34642-77-8; ALMODAN; AMOXIL INJECTION; AUGMENTININTRAVENOUS*�Amoxicillin Trihydrate 61336-70-7; AMORAM; AMOXIDIN; ¨̈̈̈̈AMOXINSOL;AMOXIL; ̈; ̈; ̈; ̈; ̈ AMOXYPEN; AUGMENTIN*; ¨̈̈̈̈BETAMOX; ¨̈̈̈̈ BIMOXYL; ¨̈̈̈̈CLAMOXYL;¨̈̈̈̈DUPHAMOX; FLEMOXIN; GALENAMOX; ¨ ¨ ¨ ¨ ¨MICROMOX; ¨̈̈̈̈QUALAMOX;¨̈̈̈̈ SYNULOX*; ¨̈̈̈̈TRIOXYL; ¨̈̈̈̈ULTRAMOX; ¨̈̈̈̈ VETREMOX; ¨̈̈̈̈ VETRIMOXIN;¨̈̈̈̈VIDAMOXAntibacterial
HO
N
NO
H2N H
O
S
H COOH
Me
Me
H HH
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1-35Amperozide am·pe·rö·zïd
4-[4,4-Bis(4-fluorophenyl)butyl]-N-ethylpiperazine-1-carboxamide; C23H29F2N3O;75558-90-6Amperozide Hydrochloride 75529-73-6Tranquilliser (veterinary)
F
F
N
N NHEt
O
Amphetamine see Amfetamine�Amphomycin
A polypeptide antibiotic produced by Streptomyces canus; 1402-82-0; amfomycin(pINN)
�Amphotericin am·fö·te·ri·sinA mixture of antifungal polyenes produced by certain strains of Streptomyces nodosusAmphotericin B: (3R,5R,8R,9R,11S,13R,15S,16R,17S,19R,34S, 35R, 36R,37S)-19-(3-amino-3,6-dideoxy-b-D-mannopyranosyloxy)-16-carboxy-3,5,8,9,11,13,15,35-octahydroxy-34,36-dimethyl-13,17-epoxyoctatriaconta-20,22,24,26,28,30,32-heptaen-37-olide; C47H73NO17; 1397-89-3; ABELCET;AMBISOME; AMPHOCIL; FUNGILIN; FUNGIZONE; ¨̈̈̈̈NEOAMFO*Antifungal
O
OHOHOHOH
O
OH
OHO O
Me
H H H H
H
HCOOH
H
HHO
H H
Me
OH
Me
H
H
H
O
Me
H
NH2OH
�Ampicillin am·pi·si·lin(6R)-6-(a-D-Phenylglycylamino)penicillanic acid; C16H19N3O4S; 69-53-4; AMFIPEN;¨̈̈̈̈AMPICAPS; ¨̈̈̈̈ LACTACLOX*; ¨̈̈̈̈ LATACILLIN; ¨̈̈̈̈ VIDOCILLIN�Ampicillin Sodium 69-52-3; AMPICLOX*; ¨̈̈̈̈EMBACILLIN-C; MAGNAPEN*;PENBRITIN (injection)�Ampicillin Trihydrate 7177-48-2; ¨̈̈̈̈COMPROPEN;¨̈̈̈̈ DUPHACILLIN;¨̈̈̈̈EMBACILLIN; ¨̈̈̈̈NOROBRITTIN ; PENBRITIN (oral); ¨̈̈̈̈VIDOCILLIN; VIDOPENAntibacterial
N
NO
H2N H
O
S
H COOH
Me
Me
H HH
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1-36Ampiroxicam am·pi·roks·i·kam
4-[1-(Ethoxycarbonyloxy)ethoxy]-2-methyl-N -(2-pyridyl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide; C20H21N3O7S; 99464-64-9;CP-65703Anti-inflammatory
HNMe
O H Me
O
N
N
OO
OOEtO
S
and enantiomer
Amprenavir am·pren·a·veer(3S)-Tetrahydro-3-furyl [(1S,2R)-1-benzyl-2-hydroxy-3-(N1-isobutylsulfanilamido)propyl]carbamate; C25H35N3O6S; 161814-49-9HIV protease inhibitor; antiviral
O NH
NS
OO
HOHH
NH2
O OH
Bu i
Amprolium am·prö·lë·um1-(4-Amino-2-propylpyrimidin-5-ylmethyl)-2-methylpyridinium chloride;C14H19ClN4; 121-25-5�Amprolium Hydrochloride 137-88-2; ¨̈̈̈̈AMPROL-PLUS*; ¨̈̈̈̈COXOIDCoccidiostat
Cl− N
N
N
NH2Me
Prn
+
�Amrinone5-Amino-3,4¢-bipyridyl-6(1H)-one; C10H9N3O; 60719-84-8
N
N
O
H2N
H
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1-37Amsacrine am·sa·krën
4¢-(Acridin-9-ylamino)methanesulfon-m-anisidide; C21H19N3O3S;51264-14-3Amsacrine Lactate AMSIDINECytotoxic
N
HN
MeO NHSO2CH3
�Amylmetacresol ä·mïl·me·ta·krë·sol6-Pentyl-m-cresol; C12H18O; 1300-94-3; STREPSILS*Anti-infective
OH
Me
CH3
Amylobarbitone see Amobarbital
Amylocaine� (BAN) a·mï·lö·kän(RS)-1-(Dimethylaminomethyl)-1-methylpropyl benzoate; C14H21NO2; 644-26-8Local anaesthetic
OCH3
ONMe2
Me
and enantiomer
Anagrelide a·na·gre·lïd6,7-Dichloro-1,5-dihydroimidazol[2,1-b]quinazolin-2(3H)-one; C10H7Cl2N3O;68475-42-3Cyclic nucleotide phosphodiesterase inhibitor; antithrombotic
N
N
NO
Cl
Cl
H
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1-38Anakinra a·na·kin·ra
N2-l-Methionylinterleukin 1 receptor antagonist (human isoform x reduced);C759H1186N208O232S10; 143090-92-0Immunomodulator
anakinra has the following amino acid sequence:M RPSGRKSSKM QAFRIWDVNQ KTFYLRNNQL VAGYLQGPNV NLEEKIDVVP IEPHALFLGI HGGKMCLSCV KSGDLTRLQL EAVNITDLSE
NRKQDKRFAF IRSDSGPTTS FESAACPGWF
LCTAMEADQP VSLTNMPDEG VMVTKFYFQE
DE
Anaritide a·na·ri·tïdN-L-arginyl-[8-L-methionine-21a-L-phenylalanine-21b-L-arginine-2lc-L-tyrosine]-atriopeptin-21 (rat); C112H175N39O35S3; 95896-08-5; Wy 47663Anaritide Acetate 104595-79-1Antihypertensive; diuretic
Arg_Ser_Ser_Cys_Phe_Gly_Gly_Arg_
Met_Asp_Arg_Ile_Gly_AlaVGln_Ser_
Gly_Leu_Gly_Cys_Asn_Ser_Phe_Arg_
Tyr
Anastrozole a·nas·tro·zôl2,2¢-Dimethyl-2,2¢-[5-(1H-1,2,4-triazol-1-ylmethyl)-1,3-phenylene]-bis(propiononitrile); C17H19N5; 120511-73-1; ARIMIDEX
Aromatase inhibitor; antineoplastic
N
N
N
CNNC
Me MeMeMe
Ancrod an·krodAn enzyme obtained from the venom of the Malayan pit-viper, Calloselasmarhodostoma Boie, 1827, formerly Agkistrodon rhodostoma, acting specifically onfibrinogen by the release of fibrinopeptide A; 9046-56-4; ARVINAnticoagulant
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1-39�Angiotensinamide (angiotensin amide) an·jë·ö·ten·sin·a·mïd
[1-Asparagine,5-valine]angiotensin II; C49H70N14O11; 53-73-6
Asn-Arg-Val-Tyr-Val-His-Pro-Phe
Anidoxime a·ni·doks·ëm3-Diethylaminopropiophenone O-(p-methoxyphenylcarbamoyl)oxime;C21H27N3O3; 34297-34-2; BRL 11870; E-142Analgesic
N
Et2N
O N
OOMe
H
Anileridine a·ni·le·ri·dënEthyl 1-(4-aminophenethyl)-4-phenylpiperidine-4-carboxylate; C22H28N2O3; 144-14-9Opioid analgesic
N
NH2
COOEt
�Anisindione a·ni·sin·dï·ön2-(4-Methoxyphenyl)indan-1,3-dione; C16H12O3; 117-37-3Anticoagulant
O
O
OMe
Anistreplase a·ni·stre·pläzp-Anisoylated (human) lys-plasminogen streptokinase activator complex(1:1);81669-57-0; APSAC; EMINASEFibrinolytic
Antazoline an·tä·zö·lënN-Benzyl-N-(2-imidazolin-2-ylmethyl)aniline; C17H19N3; 91-75-8�Antazoline Hydrochloride 2508-72-7; RBCAntazoline Phosphate 154-68-7Antazoline Sulphate 24359-81-7; OTRIVINE-ANTISTIN*Histamine H1-receptor antagonist
N
N
NH
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1-40�Antilymphocyte Immunoglobulin (Horse) (BAN)
A preparation of horse immunoglobulins containing antibodies to humanlymphocytesImmunosuppressant
Antithrombin III an·ti·throm·binThe glycoprotein antithrombin obtained from human plasma;antithrombin III human; AT III; 52014-67-2Anticoagulant
Apaflurane ä·pa·flûr·rän1,1,1,2,3,3,3-Heptafluoropropane; C3HF7; 431-89-0Pharmaceutical aid (propellant)
F3C CF3
F
Apomorphine (BAN) ä·pö·mor·fën6ab-Aporphine-10,11-diol; C17H17NO2; 58-00-4�Apomorphine Hydrochloride 314-19-2 (anhydrous);41372-20-7 (hemihydrate); BRITAJECT
Emetic; dopamine-receptor agonist
NMe
HO
HOH
Apraclonidine a·pra·klo·ni·dën2,6-Dichloro-N1-imidazolidin-2-ylidene-p-phenylenediamine; C9H10Cl2N4; 66711-21-5; AL02145Apraclonidine Hydrochloride 73218-79-8; IOPIDINEAlpha2-adrenoceptor agonist
ClN
NN
Cl
NH2
H
H
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1-41Apramycin ä·pra·mï·sin
An antimicrobial base produced by Streptomyces tenebrarius;4-O-[(2S,3R,4aS,6R,7S,8R,8aR)-3-Amino-6-(4-amino-4-deoxy-a-D-glucopyranosyloxy)-8-hydroxy-7-methylaminoperhydro-pyrano[3,2-b]pyran-2-yl]-2-deoxy-D-streptamine; C21H41N5O11; 37321-09-8�Apramycin Sulphate ¨̈̈̈̈APRALANAntibiotic
NH2
NH2HO
HO
HO
H2N
HOOH
NHMe OH
NH2
O
O
O
OO
Aprindine a·prin·dënN-(3-Diethylaminopropyl)-N-indan-2-ylaniline; C22H30N2; 37640-71-4; 99170Antiarrhythmic
N
NEt2
�Aprotinin a·prö·tï·ninA polypeptide proteinase inhibitor; C284H432N84O79S7; 9004-04-0; TRASYLOLEnzyme inhibitor (proteinase)
RPDFCLEPPY TGPCKARIIR YFYNAKAGLC
QTFVYGGCRA KRNNFKSAED CMRTCGGA
Aptocaine ap·tö·kän2-Pyrrolidin-1-ylpropiono-o-toluidide; C14H20N2O; 19281-29-9Local anaesthetic
NN
H Me
O
MeH
and enantiomer
Arbutamine ar·bü·ta·mën(R)-4-(1-Hydroxy-2-[4-(4-hydroxyphenyl)butylamino]ethyl)pyrocatechol;C18H23NO4Arbutamine Hydrochloride 125251-66-3; GENESADetection and evaluation of coronary artery disease
N
HO
H OH
OH
OHH
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1-42Ardacin ar·da·sin
A mixture of aridicin A, aridicin B, aridicin C and aridicin C2; glycopeptide antibiot-ics derived from the species Kibdelosporangium aridium, strain ATCC 39323; aridicin;C81H82Cl4N8O30(A); 117742-13-9; AAD 216; SK&F 100814Feed additive (veterinary)
HH
OH
OHOH
OH
H
O
N
NHMe
H
O
HO
OHO
Cl
ON NH
OH
H
O
OO
O
COOH
OHOH
RCOHN
Cl
ClHO
H
NHO
MeH
O
O
OH
N
O
NO
HH
Cl
HH
A: R = C9
B: R = iso C10
C: R = iso C11
Argatroban ar·ga·trö·ban(2R,4R)-4-Methyl-1-{N2-{[(3RS)-1,2,3,4-tetrahydro-3-methyl-8-quinolyl]sulfonyl}-L-arginyl}piperidine-2-carboxylic acid; C23H36N6O5S; 74863-84-6(anhydrous); 141396-28-3 (monohydrate); MCI-9038; MD-805; DK-7419; GN1600Thrombin inhibitor; anticoagulant
HN
SNH
NNH
HN
NH2 O COOHH
H
OO Me
H
MeH
and epimer at C*
*
Arginine Glutamate ar·ji·nën gloo·ta·mätL-Arginine salt of L-glutamic acid; C6H14N4O2·C5H9NO4; 74-79-3Nutrient
H2N COOH
NH H NH2
, HOOC COOH
H NH2
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1-43Argipressin ar·ji·pres·sin
[8-Arginine]vasopressin; C46H65N15O12S2; 113-79-1; PITRESSINAntidiuretic hormone
Cys_Tyr_Phe_Gln_Pro_Cys_Pro_
Arg_Gly_NH2
Arofylline a·ro·fi·lën3-(4-Chlorophenyl)-1-propylxanthine; C14H13ClN4O2; 136145-07-8;LAS 31025Phosphodiesterase inhibitor; bronchodilator
N
N
Cl
O
O
Prn
N
NH
Arprinocid ar·pri·nö·sid9-(2-Chloro-6-fluorobenzyl)adenine; C12H9ClFN5; 55779-18-5Coccidiostat
N
NN
N
Cl
F
NH2
�Arsanilic Acid ar·sa·ni·lik4-Aminophenylarsonic acid; C6H8AsNO3; 98-50-0; 110Sodium Arsanilate 127-85-5Antibacterial
As
H2N
HO
OH
O
Artemether ar·te·më·ther(3R,5aS,6R,8aS,9R,10S,12R,12aR)-Decahydro-10-methoxy-3,6,9-trimethyl-3,12-epoxy-12H-pyrano[4,3-j][1,2]benzodioxepin; C16H26O5; 71963-77-4Antimalarial
OO
O
O
Me
H
H
MeH
MeHH
H
OMe
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1-44Articaine (carticaine) ar·ti·kän
Methyl 4-methyl-3-(2-propylaminopropionamido)thiophene-2-carboxylate;C13H20N2O3S; 23964-58-1Local anaesthetic
S
Me
COOMe
NNHPrn
O
H MeH
and enantiomer
�Ascorbic Acid as·kor·bikL-ascorbic acid; vitamin C; C6H8O6; 50-81-7; ROSCORBIC; component in manyproprietary preparationsVitamin
O
OHHO
HCOH
CH2OH
O
Ascorbyl Gamolenate a·skor·bïl ga·mö·lë·nät6-O-[(6Z,9Z,12Z)-Octadeca-6,9,12-trienoyl]-L-threo-hex-2-enono-1,4-lactone;C24H36O7; 109791-32-4; SC103Treatment of diabetic neuropathy
O
OHOH
O
OH
O
O
H
Asobamast a·só·ba·mast2-Ethoxyethyl [4-(3-methyl-1,2-oxazol-5-yl)1,3-thiazol-2-yl]oxamate;C13H15N3O5S; 104777-03-9Histamine H1-receptor antagonist; antiallergic; antiasthmatic; antianaphylactic
S
NON
Me
NO
O
O
O
CH3H
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1-45�Aspartame as·par·täm
(1) (3S)-3-Amino-N-[(aS)-(a-methoxycarbonylphenethyl)]succinamic acid; (2)methyl L-aspartyl-L-phenylalaninate; C14H18N2O5; 53906-69-7; CANDERELSweetening agent
HOOC NHH2N
O H COOMe
H
�Aspirin (BAN) as·pi·rinO-Acetylsalicylic acid; C9H8O4; 50-78-2; ANGETTES; ASPAV*; CAPRIN; DISPRIN CV;EQUAGESIC*; NU-SEALS ASPIRIN; MIGRAVESS*; PLATET; RADIAN B*; ̈ RHEUMATINE; ROBAXISAL*;SOLPRIN; component in many proprietary preparationsAnalgesic; antipyretic
COOH
O CH3
O
�Astemizole as·te·mi·zôl1-(4-Fluorobenzyl)benzimidazol-2-yl[1-(4-methoxyphenethyl)-4-piperidyl]amine; C28H31FN4O; 68844-77-9; HISMANALHistamine H1-receptor antagonist
N
N
F
N
N
OMe
H
Asulacrine (BAN) a·sü·la·krën9-[2-Methoxy-4-(methylsulfonylamino)anilino]-N,5-dimethylacridine-4-carboxamide; C24H24N4O4S; 80841-47-0; CI-921; NSC 343499Inhibitor of DNA topoisomerase II; antineoplastic
N
HN
NHSO2MeMeO
CONHMeMe
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1-46�Atenolol a·ten·o·lol
(RS)-4-(2-Hydroxy-3-isopropylaminopropoxy)phenylacetamide; C14H22N2O3;29122-68-7; ANTIPRESSAN; BETA-ADALAT*; KALTEN*; TENIF*; TENORET*;TENORETIC*; TENORMIN; TOTAMOLBeta-adrenoceptor antagonist
H2N
O NHPriO
OHH
and enantiomer
Atipamezole a·ti·pa·me·zôl4-(2-Ethylindan-2-yl)imidazole; C14H16N2; 104054-27-5Atipamezole Hydrochloride 104075-48-1; ¨̈̈̈̈ANTISEDANAlpha2-adrenoceptor antagonist
NNH
Et
Atorvastatin a·tor·va·sta·tin(3R,5R)7-[2-(4-Fluorophenyl)-5-isopropyl-3-phenyl-4-(phenylcarbamoyl)pyrrol-1-yl]-3,5-dihydroxyheptanoic acid; C33H35FN2O5;134523-00-5Atorvastatin Calcium 134523-03-8; LIPITORHMG Co-A reductase inhibitor; hypolipidaemic
COOHN
F
PriHHHO OH
N
O
H
Atosiban a·tö·si·ban[1-(3-Sulfanylpropanoyl),2-(4-O-ethyltyrosine),4-L-threonine-8-L-ornithine]oxytocin; C43H67N11O12S2; 90779-69-4Oxytocin antagonist
Ile–Thr–Asn–Cys–Pro–Orn–GlyNH2NH
OEt
HO
OS
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1-47Atovaquone a·tö·va·kwön
2-[trans-4-(4-Chlorophenyl)cyclohexyl]-3-hydroxy-1,4-naphthoquinone;C22H19ClO3; 95233-18-4; MALARONE*; WELLVONEAntiparasitic
Cl
O
O
OH
H
Atracurium Besilate a·tra·kûr·rë·um be·si·lät2,2¢-(3,11-Dioxo-4,10-dioxatridecamethylene)bis(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinolinium) di(benzenesulfonate);C65H82N2O18S2; 64228-81-5; 33A74; TRACRIUMNeuromuscular blocker
N O
OMeO
MeO
MeOMeO
Me
+
OMeOMe
OMe
OMeO
NOMe
[ CH2] 5
SO
OO
-
2
mixture of stereoisomers
+
Atropine (BAN) a·trö·pën(1R,3r,5S)-Tropan-3-yl (RS)-tropate; C17H23NO3; 51-55-8�Atropine Methobromide 2870-71-5�Atropine Methonitrate 52-88-0; BROVON*�Atropine Sulphate 5908-89-6; ̈ ATROCARE; ISOPTO ATROPINE*; LOMOTIL*; MINIMS
ATROPINE; TROPERGEN*Anticholinergic
NMe
O
O
OH
H
H
and enantiomer at C*
*
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1-48Auranofin or·ra·nö·fin
S-(Triethylphosphoranediylaurio)-1-thio-b-D-glucopyranose 2,3,4,6-tetra-acetate;C20H34AuO9PS; 34031-32-8; RIDAURATreatment of rheumatoid arthritis
O
OAc
OAc
OAcS
Au
AcO
PEt3
Avilamycin a·vi·la·mï·sinAn antibiotic obtained from cultures of Streptomyces viridochromogenes, or the samesubstance produced by any other means; consists mainly of avilamycin A; 11051-71-1; ¨̈̈̈̈MAXUS
Avilamycin A: O-(1R)-4-C-acetyl-6-deoxy-2,3-O-methylene-D-galacto-pyranosylidene-(1® 3-4)-2-O-isobutyryl-a-L-lyxopyranosyl O-2,6-dideoxy-4-O-(3,5-dichloro-4-hydroxy-6-methyl-o-anisoyl)-b-D-arabino-hexopyranosyl-(1® 4)-O-2,6-dideoxy-D-arabino-hexopyranosylidene-(1® 3-4)-O-2,6-dideoxy-3-C-methyl-D-arabino-hexopyranosyl-(1® 3)-O-6-deoxy-4-O-methyl-b-D-galactopyranosyl-(1® 4)-2,6-di-O-methyl-b-D-mannopyranoside; C61H88Cl2O32;69787-79-7
Avilamycin C: 69787-80-0Antibacterial
O
OCl
HO
Cl
OMe
Me
O
Me
OMe
OOH
Me
O
OOH
Me
O
O
MeO
Me
O
OH
O
O
OMe
OHMeO
O
ORO
O
OO
O
Me
OH
Me R1
R2O
R R1 + R2
Avilamycin A: –CO–CHMe2 =O
Avilamycin C: –CO–CHMe2 –H + –OH
Aviptadil a·vip·ta·dilVasoactive intestinal polypeptide; C147H238N44O42S; 40077-57-4Treatment of erectile dysfunction
H2N-His-Ser-Asp-Ala-Val-Phe-Thr-Asp-Asn-Tyr-
Thr-Arg-Leu-Arg-Lys-Gln-Met-Ala-Val-Lys-Lys-
Tyr-Leu-Asn-Ser-Ile-Leu-Asn-NH
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1-49Avizafone a·vï·za·fön
L-Lysyl-(2¢-benzoyl-4¢-chloro-N¢-methyl)glycinanilide; C22H27ClN4O3; 65617-86-9;Ro 03-7355/000Avizafone Hydrochloride 60067-16-5; Ro 03-7355/002Anxiolytic; anticonvulsant
O NNMe
O
O
H NH2
NH2
Cl
H
Avoparcin ä·vö·par·sinA glycopeptide antibiotic obtained from cultures of Streptomycescandidus or the samesubstance obtained by any other means; 37332-99-3; ¨̈̈̈̈AVOTANAntibacterial
Azacyclonol ä·za·sï·klö·nola-Phenyl-a-4-piperidylbenzyl alcohol; C18H21NO; 115-46-8Anxiolytic
NHOH
Azalomycin a·zä·lö·mï·sinA mixture of related macrolide antibiotics produced by Streptomyces hygroscopicusvar· azalomyceticus; 54182-65-9Antibiotic
Azamethiphos (BAN) ä·za·me·thi·fosS-[(6-Chloro-2,3-dihydro-2-oxo-[1,3]oxazolo[4,5-b]pyridin-3-yl)methyl] O,O-dimethyl phosphorothioate; C9H10ClN2O5PS; 35575-96-3; CGA 18809; OMS No1825Insecticide; cholinesterase inhibitor
Cl
O
N
O
S
N
POMe
OMe
O
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1-50Azamethonium Bromide ä·za·me·thö·në·um
2,2¢-Methyliminobis(diethyldimethylammonium) dibromide; C13H33Br2N3; 306-53-6Ganglion blocker
Me2NN
NMe2
Et
Me
Et
+ +2Br
_
Azanidazole ä·za·nï·da·zôl4-[(E)-2-(1-Methyl-5-nitroimidazol-2-yl)vinyl]pyrimidin-2-ylamine; C10H10N6O2;62973-76-6Antiprotozoan
N
NO2N N
N
NH2
H
H
Me
�Azaperone ä·za·pe·rön4¢-Fluoro-4-[4-(2-pyridyl)piperazin-1-yl]butyrophenone; C19H22FN3O;1649-18-9; ¨̈̈̈̈ STRESNILTranquilliser (veterinary)
N
N N
F
O
Azapetine (BAN) ä·za·pe·tën6-Allyl-6,7-dihydro-5H-dibenz[c,e]azepine; C17H17N; 146-36-1Azapetine Phosphate 130-83-6Alpha-adrenoceptor agonist
NCH2
�Azapropazone ä·za·prö·pa·zön5-Dimethylamino-9-methyl-2-propylpyrazolo[1,2-a][1,2,4]benzotriazine-1,3(2H)-dione; apazone (USAN); C16H20N4O2; 13539-59-8; RHEUMOXAnalgesic; anti-inflammatory
NN
N
O
OMe
Prn
NMe2
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1-51Azaribine ä·za·ri·bën
(1) 2-b-D-Ribofuranosyl-1,2,4-triazine-3,5(2H,4H)-dione-2¢,3¢,5¢-triacetate; (2) 6-azauridine 2¢,3¢,5¢-triacetate; C14H17N3O9; 2169-64-4Cytotoxic
HN
NN
O
O
OAcO
AcO OAc
Azatadine ä·za·ta·dën6,11-Dihydro-11-(1-methyl-4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; C20H22N2; 3964-81-6Azatadine Maleate 3978-86-7; OPTIMINEHistamine H1-receptor antagonist
N
N
Me
Azatepa (azetepa) ä·za·të·paP,P-Bis(aziridin-1-yl)-N-ethyl-N-1,3,4-thiadiazol-2-ylphosphinamide; C8H14N5OPS;125-45-1Cytotoxic
N N
S N
Et
P O
N
N
�Azathioprine ä·za·thï·ö·prën6-(1-Methyl-4-nitroimidazol-5-ylthio)purine; C9H7N7O2S; 446-86-6; AZAMUNE;IMURANCytotoxic
HN
N
N
N
S
N
N
NO2
Me
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1-52Azelastine ä·ze·las·tën
(RS)-4-(4-Chlorobenzyl)-2-(1-methylazepan-4-yl)phthalazin-1(2H)-one;C22H24ClN3O; 58581-89-8Azelastine Hydrochloride 79307-93-0; OPTILAST; RHINOLASTProphylaxis of allergic conditions
N
N
NMeO
Cl
H
and enantiomer
Azepexole ä·ze·peks·ôl6-Ethyl-5,6,7,8-tetrahydro-4H-[1,3]oxazolo[4,5-d]azepin-2-ylamine; C9H15N3O;36067-73-9Azepexole Dihydrochloride BHT 933Alpha-adrenoceptor agonist
NEtO
NH2N
Azetepa see Azatepa
Azidamfenicol a·zï·dam·fe·ni·kol2-Azido-N-[(aR,bR)-b-hydroxy-a-hydroxymethyl-4-nitrophenethyl]acetamide;C11H13N5O5; 13838-08-9Antibacterial
N
OHH
O2N
N3
OH
OH
H
Azidocillin a·zï·dö·si·lin(6R)-6-(D-2-Azido-2-phenylacetamido)penicillanic acid; C16H17N5O4S; 17243-38-8;BRL 2534; SPC 297DAntibacterial
N
NO
N3 H
O
S
H COOH
Me
Me
H HH
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1-53Azimilide a·zim·i·lïd
(E)-{1-{[5-(4-Chlorophenyl)furfurylidene]amino}-3-[4-(4-methylpiperazin-1-yl)butyl]imidazolidine-2,4-dione; C23H28ClN5O3; 149908-53-2; NE-10064Azimilide Hydrochloride (2HCl); 149888-94-8Antiarrhythmic
NN
O
O
N
NMe
O
Cl
N
Azithromycin a·zi·thrö·mï·sin(2R,3S,4R,5R,8R,10R,11R,12S,13S,14R)-13-(2,6-Dideoxy-3-C,3-O-dimethyl-a-L-ribo-hexopyranosyloxy)-2-ethyl-3,4,10-trihydroxy-3,5,6,8,10,12,14-heptamethyl-11-(3,4,6-trideoxy-3-dimethylamino-b-D-xylohexopyranosyloxy)-1-oxa-6-azacyclopentadecan-15-one; C38H72N2O12;83905-01-5; ZITHROMAXAntibacterial
N
O
EtMe
HO
HO
Me
O
Me OHMe
Me
Me
O
NMe2
Me
OH
O
O
HO
Me
OMe
Me
O
Me
Azlocillin az·lö·si·lin(6R)-6-[N-(2-Oxoimidazolidin-1-ylcarbonyl)-D-phenylglycylamino]penicillanicacid; C20H23N5O6S; 37091-66-0�Azlocillin Sodium 37091-65-9; SECUROPENAntibacterial
H
NH
N
OH
NHHH
Me
Me
COOHH
S
ON
N
O
O
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1-54Azovan Blue (BAN) ä·zö·van
Tetrasodium 1,1¢-diamino-8,8¢-dihydroxy-7,7¢-(2,2¢-dimethylbiphenyl-4,4¢-diylbisdiazo)di(naphthalene-2,4-disulfonate); Evans Blue (USP);C34H24N6Na4O14S4; 6968-33-8Diagnostic aid
N N
OHNH2
SO3Na
NaO3S
Me2
Aztreonam az·trë·ö·nam(Z)-2-{2-Amino-1,3-thiazol-4-yl-[(2S,3S)-2-methyl-4-oxo-1-sulfoazetidin-3-ylcarbamoyl]methyleneamino-oxy}-2-methylpropionic acid; C13H17N5O8S2;78110-38-0; AZACTAMAntibacterial
S
N N
NO SO3H
Me
HH
O
NO
COOHMe
Me
H2N
H
Azuresin (BAN) a·zûr·re·sin7-Aminophenothiazin-3-ylidene(dimethyl)ammonium chloride; 8050-34-8;C14H14ClN3S; DIAGNEX BLUE
Diagnostic aid
S
N
Me2N NH2
Cl_
+
Bacampicillin ba·kam·pi·si·lin1-(Ethoxycarbonyloxy)ethyl (6R)-6-(a-D-phenylglycylamino)penicillanate;C21H27N3O7S; 50972-17-3�Bacampicillin Hydrochloride 37661-08-8; AMBAXINAntibiotic
N
S
O
NHH
O
HH2N
O OH
O
OMeH
O
CH3
MeMe
H
and enantiomer at C*
*
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1-55�Bacitracin ba·si·trä·sin
One or more antimicrobial polypeptides produced by certain strains of Bacilluslicheniformis and B· subtilis var· Tracy; 1405-87-4�Bacitracin Zinc 1405-89-6; ¨̈̈̈̈ALBAC; CICATRIN*; POLYFAX*; TYROZETS*Antibacterial
�Baclofen ba·klö·fen4-Amino-3-(4-chlorophenyl)butyric acid; C10H12ClNO2; 1134-47-0; LIORESALSkeletal muscle relaxant
Cl
COOHCH2NH2H
and enantiomer
Balipramine ba·li·pra·mën5H-3-(Dibenz[b,f]azepin-5-yl)propyldimethylamine; depramine (pINN); C19H22N2;303-54-8; GP 31406Antiparkinsonian
N
NMe2
Balsalazide bal·sal·a·zïd(E)-5-[4-(2-Carboxyethylcarbamoyl)phenylazo]-2-hydroxybenzoic acid;C17H15N3O6;80573-04-2Balsalazide Sodium 150399-21-6 (disodium, dihydrate); COLAZIDE
Anti-inflammatory
NN
OH
COOH
NHOOC
O
H
Bambermycin bam·ber·mï·sinAn antibiotic complex containing mainly moenomycins A and C obtained fromcultures of Streptomyces bambergiensis or the same substance obtained by any othermeans; bambermycins (USAN); 11015-37-5; ¨̈̈̈̈FLAVOMYCINAntibiotic (veterinary)
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1-56Bambuterol bam·bü·ter·ol
(RS)-5-(2-tert-Butylamino-l-hydroxyethyl)-m-phenylene bis(dimethylcarbamate);C18H29N3O5; 81732-65-2�Bambuterol Hydrochloride BAMBECBeta2-adrenoceptor agonist; bronchodilator
NHButH OH
OMe2N
OMe2N
O
O
and enantiomer
Bamethan ba·me·than2-Butylamino-1-(4-hydroxyphenyl)ethanol; C12H9NO2; 3703-79-5Bamethan Sulphate 5716-20-1;Vasodilator
NHBunH OH
HO
and enantiomer
Bamifylline ba·mi·fi·lën8-Benzyl-7-[2-(N-ethyl-2-hydroxyethylamino)ethyl]theophylline; C20H27N5O3;2016-63-9Bronchodilator
N
N
N
N
NOH
Et
Me
O
O
Me
Bamipine ba·mi·pënN-Benzyl-N-(1-methyl-4-piperidyl)aniline; C19H24N2; 4945-47-5Histamine H1-receptor antagonist
N
NMe
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1-57Baquiloprim ba·kwi·lö·prim
5-(8-Dimethylamino-7-methyl-5-quinolylmethyl)pyrimidin-2,4-diyldiamine;C17H20N6; 102280-35-3; ¨̈̈̈̈QUILIZINE; ¨̈̈̈̈ZAQUILAN*Antibacterial (veterinary)
N
N
N
NH2
NH2
Me
Me2N
�Barbital (barbitone) bar·bi·tal5,5-Diethylbarbituric acid; C8H12N2O3; 57-44-3Barbital Sodium 144-02-5Hypnotic
NH
N OO
EtEt
O
H
Basiliximab ba·si·liks·i·mabImmunoglobulin G 1 (human–mouse monoclonal CHI621 heavy chain anti-humaninterleukin 2 receptor), disulfide with human-mouse monoclonal CHI621 lightchain, dimer; 179045-86-4Immunomodulator
Batimastat ba·ti·ma·stat(2S,3R)-N1-Hydroxy-3-isobutyl-N4-[(S)-a-(methylcarbamoyl)phenethyl]-2-(2-thienylthiomethyl)succinamide; C23H31N3O4S2; 130370-60-4; BB-94Inhibitor of matrix metalloproteinases
HNHMe
O
S
SH
HMe
Me
HO
NH
NHOH
O
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1-58Becaplermin be×ka×pler×min
Recombinant human platelet-derived growth factor B; a recombinant proteinproduced by genetically engineered Saccharomyces cerevisiae cells that is similar inamino acid composition and biological activity to the endogenous human PDGF-BB homodimer; RWJ 60235Treatment of chronic dermal ulcers
For labelling purposes the following three-letter code, to indicate the method ofproduction is approved:
(rys) produced by fermentation using Saccharomyces cerevisiae containinga recombinant plasmid
Becaplermin has the following glycosylated amino acid sequence:
SLGSLTIAEP AMIAECKTRT EVFEISRRLI
DRTNANFLVW PPCVEVQRCS GCCNNRNVQC
RPTQVQLRPV QVRKIEIVRK KPIFKKATVT
LEDHLACKCE TVAAARPVT
dimer
Beclamide be·kla·mïdN-Benzyl-3-chloropropionamide; C10H12ClNO; 501-68-8Anticonvulsant
N Cl
O
H
Beclobrate be·klö·brätEthyl 2-(4-p-Chlorobenzylphenoxy)-2-methylbutyrate; C20H23ClO3;55937-99-0Hypolipidaemic
OCH3
Me COOEt
Cl
and enantiomer
Beclometasone (beclomethasone) be·klö·me·ta·sön9a-Chloro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione;C28H37ClO7; 4419-39-0�Beclometasone Dipropionate 5534-09-8; AEROBEC; BECLAZONE;BECLOFORTE; BECODISKS; BECONASE; BECOTIDE; BDP SPACEHALER; FILAIR;NASOBEC; PROPADERM; VENTIDE*; ZONIVENTCorticosteroid
O
Me
Cl
HO
H
H
Me
Me OHO
OH
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1-59Bemegride be·me·grïd
3-Ethyl-3-methylglutarimide; C8H13NO2; 64-65-3Central nervous system stimulant
N OO
Me Et
H
Bemetizide be·me·ti·zïd6-Chloro-3,4-dihydro-3-(1-phenylethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; C15H16ClN3O4S2; 1824-52-8Diuretic
O O
Cl
H2NSO2
NH
SNH
H Me
and enantiomer
Benactyzine be·nak·tï·zën2-Diethylaminoethyl benzilate; C20H25NO3; 302-40-9Anxiolytic
HOO
O
NEt2
�Benapryzine (BAN)2-(N-Ethylpropylamino)ethyl benzilate; C21H27NO3; 22487-42-9
ON
O
Prn
Et
HO
Benazepril be·nä·ze·pril{(3S)-3-[(1S)-1-Ethoxycarbonyl-3-phenylpropylamino]-2,3,4,5-tetrahydro-2-oxo-1H-1-benzazepin-1-yl}acetic acid; C24H28N2O5 ;86541-75-5Benazepril Hydrochloride 86541-74-4; ¨̈̈̈̈FORTEKORAngiotensin-converting enzyme inhibitor
H
NEtOOC
HN
O
H
COOH
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1-60Bendazac ben·da·zak
(1-Benzylindazol-3-yloxy)acetic acid; C16H14N2O3; 20187-55-7Analgesic; anti-inflammatoryBendazac Lysine 81919-14-4; AF 1934Treatment of cataracts
NN
O COOH
�Bendroflumethiazide/Bendrofluazide ben·drö·floo·a·zï/ben·drö·floo·me·thï·a·zïd3-Benzyl-3,4-dihydro-6-trifluoromethyl-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; C15H14F3N3O4S2; 73-48-3; APRINOX; BERKOZIDE;CORGARETIC*; INDERETIC*; INDEREX*; MEROCAINE*; NEO-NACLEX; PRESTIM*Diuretic
SNH
N
OO
F3C
H2NSO2
H
�Benethamine Penicillin be·ne·tha·mënBenzyl(phenethyl)ammonium (6R)-6-(2-phenylacetamido)penicillanate;C16H17N2O4S.C15H18N; 751-84-8Antibacterial
H
H2N
Ph
Ph
N
S
OH COO
_
MeMe
N HH
O+
�Benorilate (benorylate) be·no·ri·lät4-Acetamidophenyl O-acetylsalicylate; C17H15NO5; 5003-48-5; BENORALAnalgesic; anti-inflammatory
O
OOAcNHAc
�Benoxaprofen2-(2-p-Chlorophenyl-1,3-benzoxazol-5-yl)propionic acid; C16H12ClNO3; 51234-28-7
N
O
COOH
H Me
Cl
and enantiomer
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1-61Benperidol ben·pe·ri·dol
1-{1-[3-(4-Fluorobenzoyl)propyl]-4-piperidyl}benzimidazolin-2-one;C22H24FN3O2; 2062-84-2; ANQUILAntipsychotic
H
N
N
F
O
ON
Benserazide ben·se·ra·zïd2-Amino-3-hydroxy-2¢-(2,3,4-trihydroxybenzyl)propionohydrazide; C10H15N3O5;322-35-0Benserazide Hydrochloride 14046-64-1; MADOPAR*Dopa-decarboxylase inhibitor
NN
O
H NH2OH
HO OH
OH
H
H
and enantiomer
Bensuldazic Acid ben·sul·dä·zik(5-Benzyl-6-thioxo-1,3,5-thiadiazin-3-yl)acetic acid; C12H14N2O2S2;1219-77-8Sodium Bensuldazate 1950-15-8 ¨̈̈̈̈DEFUNGITAntifungal
N
S
N
S
COOH
Bentiromide ben·ti·rö·mïd4-(N-Benzoyl-L-tyrosylamino)benzoic acid; C23H20N2O5; 37106-97-1;Ro 11-7891Diagnostic aid (determination of pancreatic function)
N
NH
O
HO
H
O
COOH
H
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1-62�Benzalkonium Chloride ben·zal·kö·në·um
Alkylbenzyldimethylammonium chlorides; 8001-54-5; ¨̈̈̈̈AGRICLENS; BRADOSOL;CONOTRANE*; DERMOL 500*; DRAPOLENE*; EMULSIDERM*; IONAX SCRUB; IONILT*; ¨̈̈̈̈MARINOL; OILATUM PLUS*; ¨̈̈̈̈OPTHAIN*; ¨̈̈̈̈ SLIPJEL; TIMODINE*;TORBETOL*;Anti-infective
�Benzathine Benzylpenicillin (benzathine penicillin) ben·za·thënN,N¢-Dibenzylethylenediammonium bis[(6R)-6-(2-phenylacetamido)penicillanate];penicillin G benzathine (USP); (C16H17N2O4)2.C16H22N2; 1538-09-6; ̈̈̈̈̈ DEPOPEN-P*;¨̈̈̈̈DUPHAPEN*; ¨̈̈̈̈DUPLOCILLIN*; ¨̈̈̈̈ETHACILIN; ¨̈̈̈̈LENTRAX*; ¨̈̈̈̈NOVOCILLIN;¨̈̈̈̈ PENILLIN; ¨̈̈̈̈ PROPEN*Antibiotic
NH2
H2N Ph
PhH
N
S
OH COO
_
MeMe
N HH
O
+
+
2
Benzatropine (benztropine) ben·za·trö·pën(1R,3r,5S)-3-Benzhydryloxytropane; C21H25NO;86-13-5�Benzatropine Mesilate 132-17-2; COGENTINAnticholinergic
NMe
O
Benzbromarone benz·brö·ma·rön3,5-Dibromo-4-hydroxyphenyl 2-ethylbenzofuran-3-yl ketone; C17H12Br2O3; 3562-84-3Uricosuric
O Et
O
Br
OH
Br
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1-63Benzestrol benz·ës·trol
4,4¢-(1,2-Diethyl-3-methyltrimethylene)diphenol; C20H26O2; 85-95-0Oestrogen
Et H
EtH
H Me
OHHO
mixture of 8 stereoisomers
�BenzethidineEthyl 1-(2-benzyloxyethyl)-4-phenylpiperidine-4-carboxylate; C23H29NO3; 3691-78-9
ON
COOEt
�Benzethonium Chloride ben·ze·thö·në·umBenzyldimethyl-2-{2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethoxy}-ethylammonium chloride; C27H42ClNO2; 121-54-0; EMKO*Anti-infective
OO
NMeMe
MeMe
MeMe
MeCl−
+
Benzfetamine (benzphetamine) benz·fet·a·mën(+)-N-Benzyl-N,a-dimethylphenethylamine; C17H21N; 156-08-1Appetite suppressant
N
Me
Me
Benzhexol see Trihexyphenidyl
Benzilonium Bromide ben·zi·lö·në·um3-Benziloyloxy-1,1-diethylpyrrolidinium bromide; C22H28BrNO3;1050-48-2Anticholinergic
NEt2
O
HO
O+
Br_
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1-64Benziodarone ben·zï·ö·da·rön
2-Ethylbenzofuran-3-yl 4-hydroxy-3,5-di-iodophenyl ketone; C17H12I2O3;68-90-6Vasodilator
O Et
O
I
OH
I
�Benzocaine ben·zö·känEthyl 4-aminobenzoate; C9H11NO2; 94-09-7; component in many proprietarypreparationsLocal anaesthetic
COOEt
H2N
�Benzoctamine ben·zok·ta·mën9,10-Dihydro-9,10-ethanoanthracen-9-ylmethyl(methyl)amine; C18H19N; 17243-39-9Benzoctamine Hydrochloride 10085-81-1Anxiolytic
CH2NHMe
Benzonatate ben·zö·na·tät3,6,9,12,15,18,21,24,27-Nonaoxaoctacosyl 4-butylaminobenzoate; C30H53NO11;104-31-4Antitussive
O
BunHN
O
CH2CH2O CH39
Benzphetamine see Benzfetamine
Benzquinamide benz·kwi·na·mïd3-Diethylcarbamoyl-1,3,4,6,7,11b-hexahydro-9,10-dimethoxy-2H-benzo[a]quinolizin-2-yl acetate; C22H32N2O5; 63-12-7Antiemetic
NMeO
MeO
OAc
CONEt2
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1-65Benzthiazide benz·thï·a·zïd
3-Benzylthiomethyl-6-chloro-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide; C15H14ClN3O4S3; 91-33-8; DYTIDE*Diuretic
S
O O
Cl
H2NSO2
N
SNH
Benztropine see Benzatropine
Benzydamine ben·zï·da·mën3-(1-Benzylindazol-3-yloxy)propyldimethylamine; C19H23N3O; 642-72-8Benzydamine Hydrochloride 132-69-4; DIFFLAMAnalgesic; anti-inflammatory
O NMe2
NN
Benzylpenicillin ben·zïl·pe·ni·si·lin(6R)-6-(2-Phenylacetamido)penicillanic acid; C16H18N2O4S; 61-33-6�Benzylpenicillin Potassium 113-98-4�Benzylpenicillin Sodium 69-57-8; BICILLIN*; CRYSTAPENAntibacterial
N
NOO
S
H COOH
Me
Me
H HH
Bephenium Hydroxynaphthoate be·fë·në·um hï·droks·ë·naf·thö·ätBenzyldimethyl-2-phenoxyethylammonium 3-hydroxy-2-naphthoate; C28H29NO4;3818-50-6; ¨̈̈̈̈FRANTIN*Anthelmintic
+
COO−
OH
ONMe2
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1-66Bepridil be·pri·dil
N-Benzyl-N-(3-isobutoxy-2-pyrrolidin-1-ylpropyl)aniline; C24H34N2O; 64706-54-3Bepridil Hydrochloride 74764-40-2; Org 5730Calcium antagonist
N
NOMe
HMe
and enantiomer
Beractant (BAN) be·rak·tantA modified bovine lung extract containing mostly phospholipids, modified by theaddition of dipalmitoylphosphatidyl choline (DPPC), palmitic acid and tripalmitin;108778-82-1; SURVANTA
Lung surfactant; treatment of respiratory distress syndrome
Betacetylmethadol bë·ta·së·tïl·meth·a·dol4-Dimethylamino-1-ethyl-2,2-diphenylpentyl acetate (b-form); C23H31NO2; 17199-59-6Opioid analgesic
HMe2N
H3CH OAc
CH3
Betahistine bë·ta·his·tënMethyl-2-(2-pyridyl)ethylamine; C8H12N2; 5638-76-6Betahistine Dihydrochloride 5579-84-0; SERC�Betahistune MesilateVasodilator
N NHMe
Betameprodine bë·ta·me·prö·dën(3S,4S)-3-Ethyl-1-methyl-4-phenyl-4-piperidyl propionate; C17H25NO2;468-50-8Opioid analgesic
NMe
OOCEt
HEt
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1-67Betamethadol bë·ta·me·tha·dol
6-Dimethylamino-4,4-diphenylheptan-3-ol (b-form); C21H29NO;17199-55-2Opioid analgesic
HMe2N
H3CH OH
CH3
�Betamethasone bë·ta·me·tha·sön9a-Fluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione; C22H29FO5; 378-44-9; BETNELAN; ¨̈̈̈̈BETSOLAN; ¨̈̈̈̈DUPHACORT;¨̈̈̈̈NORBET�Betamethasone Acetate 987-24-6Betamethasone Adamantoate 40242-27-1; ¨̈̈̈̈BETSOVET*�Bethamethasone Dipropionate 5593-20-4; ¨̈̈̈̈CANISONE; DIPROSALIC*;DIPROSONE; LOTRIDERM*�Bethamethasone Sodium Phosphate 151-73-5; BETNESOL; ¨̈̈̈̈BETSOLANSOLUBLE; ¨̈̈̈̈BETSOVET*; ¨̈̈̈̈OTERNA*; ¨̈̈̈̈ STREPTOVIN*; VISTA-METHASONE�Betamethasone Valerate 2152-44-5; BETACAP; BETNOVATE; BETTAMOUSSE;BEXTASOL; FUCIBET*; ¨̈̈̈̈ VETSOVATECorticosteroid
O
Me
HO
F H
H
Me
Me
OOH
OH
Betamethasone Acibutate a·së·bü·tät9a-Fluoro-11b-hydroxy-16b-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl 21-acetate 17-isobutyrate; C28H37FO7; 5534-05-4Corticosteroid
O
Me
HO
F H
H
Me
Me
OOAc
OCOPr i
Betanidine (bethanidine) be·ta·ni·dën2-Benzyl-1,3-dimethylguanidine; C10H15N3; 55-73-2�Betanidine Sulphate 114-85-2; BENDOGENAdrenergic neurone blocker
N NHMe
NMe
H
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1-68Betaprodine bë·ta·prö·dën
(3S,4S)-1,3-Dimethyl-4-phenyl-4-piperidyl propionate; C16H23NO2;468-59-7Opioid analgesic
MeNOCOEt
MeH
Betaxolol bë·taks·o·lol1-[4-(2-Cyclopropylmethoxyethyl)phenoxyl-3-isopropylaminopropan-2-ol; C18H29NO3; 63659-18-7�Betaxolol Hydrochloride 63659-19-8; BETOPTIC; KERLONEBeta-adrenoceptor antagonist
O NHPriH OH
O
and enantiomer
Bethanechol Chloride (BAN) be·tha·ne·kol2-Carbamoyloxypropyltrimethylammonium chloride; C7H17ClN2O2;590-63-6; MYOTONINE
Cholinergic
H2N ONMe3
MeHO+
Cl_
and enantiomer
Bethanidine see Betanidine
Betiatide bë·tï·a·tïd[(Benzoylthio)acetyl]glycylglycylglycine; C15H17N3O6S; 103725-47-9; TECHNESCANRadiodiagnostic aid to renal scintigraphy
SN
NH
O
O
O
NH
O
HOOC
H
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1-69Bevantolol be·van·to·lol
1-(3,4-Dimethoxyphenethylamino)-3-m-tolyloxypropan-2-ol; C20H27NO4; 59170-23-9Bevantolol Hydrochloride 42864-78-8; CI 775Beta-adrenoceptor antagonist
O N
Me
H OHOMe
OMe
H
and enantiomer
Bevonium Metilsulfate be·vö·në·um më·thïl·sul·fät2-Benziloyloxymethyl-1,1-dimethylpiperidinium methylsulfate, C23H31NO7S; 5205-82-3Anticholinergic
CH3SO4NMe2
O
O
OH
+_
Bexarotene beks·a·rö·tën4-[1-(5,6,7,8-Tetrahydro-3,5,5,8,8-pentamethyl-2-naphthyl)vinyl]benzoic acid;C24H28O2; 153559-49-0Antineoplastic; antidiabetic
Me Me
MeMeMe
CH2
COOH
Bezafibrate bë·za·fï·brät2-[4-(2-p-Chlorobenzamidoethyl)phenoxy]-2-methylpropionic acid; C19H20ClNO4;41859-67-0; BEZALIPHypolipidaemic
O COOH
Me MeN
O
Cl
H
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1-70Bezitramide be·zi·tra·mïd
4-[4-(2,3-Dihydro-2-oxo-3-propionyl-1H-benzimidazol-l-yl)piperidino]-2,2-diphenylbutyronitrile; C31H32N4O2; 15301-48-1Opioid analgesic
N
N O
CN
N
OCH3
Bialamicol bï·a·la·mi·kol3,3¢-Diallyl-5,5¢-bis(diethylaminomethyl)biphenyl-4,4¢-diol; C28H40N2O2; 493-75-4Antiprotozoan
H2C
HO
CH2
OHNEt2Et2N
Bibapcitide bï·bap·si·tïdS13,S13¢-[Oxybis(methylene)(2,5-dioxopyrrolidin-1,3-diyl)]bis[N1,S5-(1-oxoethano)-D-tyrosyl-S-(3-aminopropyl)-L-cysteinylglycyl-L-a-aspartyl-L-cysteinylglycylglycyl-S-(acetamidomethyl)-L-cysteinylglycyl-S-(acetamidomethyl)-L-cysteinylglycylglycyl-L-cysteinamide; C112H162N36O43S10; 153507-46-1Diagnostic agent
D-Tyr_Cys_Gly_Asp_Cys_Gly_Gly_
NH2
N
O
O
ONHAcNHAc
Cys_Gly_Cys_Gly_Gly_Cys_NH2H2C
O
2
s s s
s
Bibenzonium Bromide bï·ben·zö·në·um2-(1,2-Diphenylethoxy)ethyltrimethylammonium bromide; C19H26BrNO; 15585-70-3Antitussive
and enantiomer
ONMe3 Br
H
+ _
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1-71Bicalutamide bï·ka·loo·ta·mïd
(RS)-4¢-Cyano-a¢,a¢,a¢-trifluoro-3-(4-fluorophenylsulfonyl)-2-hydroxy-2-methylpropiono-m-toluidide; C18H14F4N2O4S; 90357-06-5; CASODEXAnti-androgen
and enantiomer
O OS
F
MeHN
ONC
CF3
HO
Biciromab bï·si·rö·mabMouse T2Gls cell anti-human fibrin II b-chain monoclonal immunoglobulin G Fab¢fragment; FIBRISCINTDiagnostic agent
Bidimazium Iodide bi·di·mä·zë·um4-(Biphenyl-4-yl)-2-(4-dimethylaminostyryl)-3-methyl-1,3-thiazolium iodide;C26H25IN2S; 21817-73-2; 65-318Anthelmintic
NMe
S CH CH
NMe2+ I_
Bifluranol bï·flûr·ra·nol(1R,2S)-4,4¢-(1-Methyl-2-ethylethylene)bis(3-fluorophenol); C17H18F2O2; 34633-34-6; BX 341Treatment of benign hypertrophy of the prostate
OH
F
F
HO
H Me
H Et
Bifonazole bï·fo·na·zôl1-(a-Biphenyl-4-ylbenzyl)imidazole; C22H18N2; 60628-96-8; BAY h 4502Antifungal
NN
PhH
and enantiomer
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1-72Bile Salts (BAN)
The sodium salts of glycocholic and taurocholic acids, concerned with the digestionand absorption of fats; OPOBYL*
Bioallethrin (BAN) bï·ö·a·lë·thrin(RS)-3-Allyl-2-methyl-4-oxocyclopent-2-enyl (1R,3R)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate; C19H26O3; 584-79-2;28434-00-6 (S-isomer)Pyrethroid insecticide
and epimer at C*
Me
Me
H
Me
Me
H
Me
O
CH2
O
OH
*
Biperiden bï·pe·ri·den1-(Bicyclo[2.2.1]hept-2-en-5-yl)-1-phenyl-3-piperidinopropan-1-ol; C21H29NO;514-65-8�Biperiden Hydrochloride 1235-82-1; AKINETONBiperiden Lactate 7085-45-2; AKINETON INJECTIONAnticholinergic
N
OH
and enatiomer
�Biphasic Insulin Injection (BAN)A sterile suspension of beef insulin in a solution of pork insulin;8063-29-4; RAPITARD MC
Hypoglycaemic�Biphasic Isophane Insulin Injection (BAN)
A sterile suspension of beef insulin complexed with protamine in a solution of porkinsulin or a sterile suspension of human insulin complexed with protamine in asolution of human insulin; 8063-29-4; HUMAN ACTRAPHANE; HUMAN INITARD; HUMAN
MIXTARD; HUMULINS M1-M5; MIXTARD; PENMIX; PORK MIXTARD; PUR-IN MIX
Hypoglycaemic
�Bisacodyl bi·sa·kö·dïl4,4¢-(2-Pyridylmethylene)di(phenyl acetate); C22H19NO4; 603-50-9; DULCOLAXLaxative
N
HOAcAcO
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1-73Bismuth Glycollylarsanilate see Glycobiarsol
Bisoprolol bï·so·pro·lol1-[4-(2-Isopropoxyethoxymethyl)phenoxy]-3-isopropylaminopropan-2-ol;C18H31NO4; 66722-44-9Bisoprolol Fumarate 66722-45-0; EMCOR; MONOCOR; MONOZIDE*Beta-adrenoceptor antagonist
and enantiomer
OOMe
MeO
OHHNHPri
Bisoxatin bi·soks·a·tin2,2-Bis(4-hydroxyphenyl)-2H-1,4-benzoxazin-3(4H)-one; C20H15NO4; 17692-24-9Laxative
O
NH
O
OH
OH
Bithionol bï·thï·o·nol2,2¢-Thiobis(4,6-dichlorophenol); C12H6Cl4O2S; 97-18-7Anti-infective
OH
Cl
Cl
S
OH
Cl
Cl
Bitolterol bï·tol·te·rol4-[2-(tert-Butylamino)-1-hydroxyethyl]-o-phenylene di-p-toluate; C28H31NO5;30392-40-6Bitolterol Mesilate 30392-41-7; WIN 32784Beta-adrenoceptor agonist
O O
Me Me
O O
NHButHOH
and enantiomer
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1-74Bivalirudin bï·va·li·roo·din
D-Phe–Pro–Arg–Pro–Gly–Gly–Gly–Gly–
Asn–Gly–Asp–Phe–Glu–Glu–Ile–Pro–
Glu–Glu–Tyr–Leu
C98H138N24O33; 128270-60-0; BG8967Direct thrombin inhibitor; anticoagulant
Bleomycin blë·ö·mï·sinA mixture of glycopeptide antibiotics produced by Streptomyces verticillus; 11056-06-7�Bleomycin Sulphate 9041-93-4; BLEOMYCIN LUNDBECKCytotoxic
H
H
H
A2: R = _NH[CH2]3SMe2
+
B2: R = _NH[CH2]4NH
C
NH
NH2O
OHO
OH
OH
N N
HNMe
OO HO
N MeO
N
HO Me
NH N
S
H2N
Me OH
H
NS
O RN
NH2
NH2
ONH2H
O
H
O N
NHO
OHO
CONH2
OH
OH
H
�Boldenone bol·de·nön17b-Hydroxyandrosta-1,4-dien-3-one; C30H44O3; 846-48-0Boldenone Undecenoate 13103-34-9Anabolic steroid; androgen
O
OH
Me
Me
H H
H
Bolmantalate bol·man·ta·lät3-Oxoestr-4-en-17b-yl adamantane-1-carboxylate; C29H40O3; 1491-81-2Anabolic steroid; androgen
H
HH
Me
H
O
O
O
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1-75Bornaprine bor·na·prën
3-Diethylaminopropyl 2-phenylbicyclo[2.2.1]heptane-2-carboxylate; sormodren;C21H31NO2; 20448-86-6Anticholinergic
O NEt2
O
Bovactant (BAN) bö·vak·tantAn extract of bovine lung containing about 92% of phospholipids, 3·2% ofcholesterol, 0·6% of surfactant-associated hydrophobic proteins and 0·4% of freefatty acid; mean relative molecular mass of phospholipids, about 760;SF-Rl 1Surfactant replacement therapy
Bovine Fibrin (BAN)An insoluble plasma protein obtained by the action of bovine thrombin on bovinefibrinogen; HEMOFIBRINE
Dental resorbable haemostatic
Bretylium Tosilate bre·ti·lë·um2-Bromobenzyl-N-ethyldimethylammonium p-toluenesulfonate; C18H24BrNO3S; 61-75-6; BRETYLATE; ¨̈̈̈̈MIN-I-JET BRETYLIUM TOSYLATEAdrenergic neurone blocker
NMe2
Et
Br
Me
SO3+_
Brimonidine brï·mo·ni·dën5-Bromoquinoxalin-6-yl(2-imidazolin-2-yl)amine; C11H10BrN5; 59803-98-4; UK-14304-18Brimonidine Tartrate 79570-19-7; ALPHAGANAlpha2-adrenoceptor agonist; antihypertensive
NH
NHN N
N
Br
Brinzolamide brin·zol·a·mïd(R)-4-(Ethylamino)-3,4-dihydro-2-(3-methoxypropyl)-2H-thieno[3,2-e][1,2]thiazine-6-sulfonamide1,1-dioxide; C12H21N3O5S3; 138890-62-7Vasodilator; antihypertensive
NS S S
OO
MeO
NHEtH
NH2
O O
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1-76Brocresine brö·kre·sën
a-Amino-oxy-6-bromo-m-cresol; C7H8BrNO2; 555-65-7Histidine decarboxylase inhibitor
ONH2HO
Br
Brofezil brö·fe·zil2-(4-p-Bromophenyl-1,3-thiazol-2-yl)propionic acid; C12H10BrNO2S;17969-45-8Brofezil Sodium ICI 54594Analgesic; anti-inflammatory
N
S
Br
COOH
H Me
and enantiomer
�Bromazepam brö·mä·ze·pam7-Bromo-1,3-dihydro-5-(2-pyridyl)-1,4-benzodiazepin-2-one; C14H10BrN3O; 1812-30-2; LEXOTANAnxiolytic
N
N
N
Br
OH
Bromazine (bromodiphenhydramine) brö·ma·zën2-(4-Bromobenzhydryloxy)ethyldimethylamine; C17H20BrNO; 118-23-0Histamine H1-receptor antagonist
ONMe2
Br
H
and enantiomer
Bromebric Acid brö·me·brik(E)-3-p-Anisoyl-3-bromoacrylic acid; C11H9BrO4; 5711-40-0Sodium BromebrateCytotoxic
H
MeO
O
Br
COOH
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1-77Bromelains brö·me·läns
A concentrate of proteolytic enzymes derived from Ananas comosus Merr·; 9001-00-7Enzyme
Bromhexine brom·heks·ën2-Amino-3,5-dibromobenzyl(cyclohexyl)methylamine; C14H20Br2N2;3572-43-8�Bromhexine Hydrochloride 611-75-6; ¨̈̈̈̈BISOLVON; ¨̈̈̈̈BISOLVOMYCIN*;¨̈̈̈̈ORALJECT MUCOLYSEExpectorant
N
Me
NH2
Br
Br
Bromindione brö·min·dï·ön2-(4-Bromophenyl)indan-1,3-dione; C15H9BrO2; 1146-98-1Anticoagulant
O
O
Br
�Bromociclen (bromocyclen) brö·mö·sï·klen5-Bromomethyl-1,2,3,4,7,7-hexachloronorborn-2-ene; C8H5BrCl6;1715-40-8Insecticide; acaricide
Cl Cl
Cl
Cl
Cl
Br Cl
Bromocriptine brö·mö·krip·tën(1) 5¢S)-2-Bromo-12¢-hydroxy-2¢-isopropyl-5¢-isobutylergotaman-3¢,6¢,18-trione;(2) 2-bromo-a-ergocryptine; C32H40BrN5O5; 25614-03-3�Bromocriptine Mesilate 22260-51-1; PARLODELDopamine-receptor agonist
NO
N
Me
OO
OH
H
H
Me
Pri
NH
O
HN
NBrH
Me
H
Bromocyclen see Bromociclen
Bromodiphenhydramine see Bromazine
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1-78Bromperidol brom·pe·ri·dol
4-(4-p-Bromophenyl-4-hydroxypiperidino)-4¢-fluorobutyrophenone;C21H23BrFNO2; 10457-90-6; R 11333Bromperidol Decanoate 75067-66-2; R 46541Antipsychotic
N
F
OHO
Br
Brompheniramine brom·fe·nï·ra·mën3-(4-Bromophenyl)-3-(2-pyridyl)propyldimethylamine; C16H19BrN2;86-22-6�Brompheniramine Maleate 980-71-2; DIMOTANE; DIMOTANE PLUS*; DIMOTAPPP*;Histamine H1-receptor antagonist
and enantiomer
N
Br
NMe2H
�Bronopol brö·nö·pol2-Bromo-2-nitropropane-1,3-diol; C3H6BrNO4; 52-51-7Anti-infective
HO OHNO2Br
Bropirimine brö·pi·ri·mën2-Amino-5-bromo-6-phenylpyrimidin-4(3H)-one; C10H8BrN3O;056741-95-8; U54,461S; U-54,461Antineoplastic
NH
N NH2
O
Br
Brotianide brö·tï·a·nïd2-Bromo-6-(4-bromophenylthiocarbamoyl)-4-chlorophenyl acetate;C15H10Br2ClNO2S; 23233-88-7Anthelmintic
N
OAc
SBr
Br
Cl
H
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1-79Brotizolam brö·tï·zö·lam
2-Bromo-4-(2-chlorophenyl)-9-methyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine; C15H10BrClN4S; 57801-81-7; We 941-BSHypnotic
N
NNN
S
Cl
Me
Br
Bucetin bü·së·tin3-Hydroxybutyro-p-phenetidine; C12H17NO3; 1083-57-4Analgesic
EtO
N CH3
O H OH
Hand enantiomer
Bucindolol bü·sin·do·lol2-{2-Hydroxy-3-[2-(indol-3-yl)-1,1-dimethylethylamino]propoxy}benzonitrile;C22H25N3O2; 71119-11-4Bucindolol Hydrochloride 70369-47-0; MJ 13105-1Beta-adrenoceptor antagonist
HO N
CN
H OH
Me MeNH
and enantiomer
Buclizine bü·kli·zën(RS)-1-(4-tert-Butylbenzyl)-4-(4-chlorobenzhydryl)piperazine; C28H33ClN2; 82-95-1�Buclizine Hydrochloride 129-74-8; MIGRALEVE*Antiemetic
NN
HBut
Cl
and enantiomer
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1-80Buclosamide bü·klö·za·mïd
N-Butyl-4-chlorosalicylamide; C11H14ClNO2; 575-74-6Antifungal
CONHBun
OHCl
�Budesonide bü·de·so·nïd16a,17a-Butylidenedioxy-11b,21-dihydroxypregna-1,4-diene-3,20-dione;C25H34O6; 51333-22-3; BUDENOFALK; ENTOCORT; PREFERID; PULMICORT;RHINOCORTCorticosteroid
O
O
HH
HCH3
O
CH3
O
H
H
CH3HO
H
OH
and epimer at C*
*
�Bufexamac bü·feks·a·mak2-(4-Butoxyphenyl)acetohydroxamic acid; C12H17NO3; 2438-72-4Analgesic; anti-inflammatory
N
OH3CO
OH
H
Buflomedil bü·flö·me·dil2¢,4¢,6¢-Trimethoxy-4-(pyrrolidin-1-yl)butyrophenone; C17H25NO4;55837-25-7Buflomedil Hydrochloride 35543-24-9Vasodilator
N
O
OMeMeO
OMe
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1-81Bufrolin bü·fro·lin
6-Butyl-1,4,7,10-tetrahydro-4,10-dioxo-1,7-phenanthroline-2,8-dicarboxylic acid; C18H16N2O6; 54867-56-0Bufrolin Sodium ICI 74917Anti-allergic
N
HNO
HOOC
O
COOH
BunH
Bufuralol bü·fûr·ra·lol2-tert-Butylamino-1-(7-ethylbenzofuran-2-yl)ethanol; C16H23NO2;54340-62-4Bufuralol Hydrochloride Ro 03-4787Beta adrenoceptor antagonist
O NHBu tH OHEt
and enantiomer
Bufylline (BAN) bü·fi·lënTheophylline salt of 2-amino-2-methylpropan-1-ol (1:1); ambuphylline (USAN);C7H8N4O2.C4H11NO; 5634-34-4Bronchodilator
MeN
N
N
N
O
O
Me
H
H2N
Me MeOH
Bumetanide bü·me·ta·nïd3-Butylamino-4-phenoxy-5-sulfamoylbenzoic acid; C17H20N2O5S;28395-03-01; BURINEXDiuretic
SNH2
BunHNOO
COOH
O
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1-82Bunamidine bü·na·mi·dën
N1,N1-Dibutyl-4-hexyloxy-1-naphthamidine; C25H38N2O; 3748-77-4�Bunamidine Hydrochloride 1055-55-6; ¨̈̈̈̈COOPER¢S HEAD TO TAIL;Anthelmintic
NBun2HN
O CH3
Bunamiodyl (buniodyl) bü·na·mï·ö·dïl3-Butyramido-a-ethyl-2,4,6-tri-iodocinnamic acid; C15H16I3NO3; 1233-53-0Contrast medium
COOH
CH3I
II
PrnCONH
Buniodyl see Bunamiodyl
Buparvaquone bü·par·va·kwöntrans-2-(4-tert-Butylcyclohexylmethyl)-3-hydroxy-1,4-naphthoquinone; C21H26O3;88426-33-9; BW 720CTheilericide (veterinary)
O
O
OH But
Buphenine bü·fe·nën1-(4-Hydroxyphenyl)-2-(1-methyl-3-phenylpropylamino)propan-1-ol; nylidrin(USAN); C19H25NO2; 447-41-6Vasodilator
N
HO
H OH
Me H H Me
H
mixture of isomers
* * *
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1-83Bupivacaine bü·pi·va·kän
1-Butyl-2-piperidylformo-2¢,6¢-xylidide; C18H28N2O; 2180-92-9�Bupivacaine Hydrochloride 14252-80-3 (monohydrate); 18010-40-7 (anhydrous);MARCAINLocal anaesthetic
NN
Me
Me
OBun
H H
and enantiomer
Buprenorphine bü·pre·nor·fën(1) (2S)-2-[(-)-(5R,6R,7R,14S)-9a-Cyclopropylmethyl-4,5-epoxy-3-hydroxy-6-methoxy-6,14-ethanomorphinan-7-yl]-3,3-dimethylbutan-2-ol;(2) (6R,7R,14S)-17-cyclopropylmethyl-7,8-dihydro-7-[(1S)-1-hydroxy-1,2,2-trimethylpropyl]-6-O-methyl-6,14-ethano-17-normorphine; C29H41NO4;52485-79-7Buprenorhine Hydrochloride 53152-21-9; SUBUTEX; TEMGESIC; ¨̈̈̈̈VETERGESICOpioid analgesic
N
O
HO
MeOHMe
HO But
Bupropion see Amfebutamone
Buquineran bü·kwi·ner·ran1-Butyl-3-[1-(6,7-dimethoxyquinazolin-4-yl)-4-piperidyl]urea; C20H29N5O3; 59184-78-0; UK-14275Cardiac stimulant
N N
N
NH
NHBunMeO
OMe
O
�Buserelin bü·se·re·linC60H86N16O13; 57982-77-1Buserelin Acetate 68630-75-1; ¨RECEPTAL; SUPREFACT; SUPRECURGonadorelin analogue; pituitary gonadotrophin liberator
5-oxoPro–His–Trp–Ser–Tyr–D-Ser(tert-Bu)–
Leu–Arg–Pro–NHEt
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1-84Buspirone bü·spi·rön
8-{4-[4-(Pyrimidin-2-yl)piperazin-1-yl]butyl}-8-azaspiro[4.5]decane-7,9-dione; C21H31N5O2; 36505-84-7Buspirone Hydrochloride 33386-08-2; BUSPARAnxiolytic
N
ON
N
N
N
O
�Busulfan (busulphan) bü·sul·fanTetramethylene di(methanesulfonate); C6H14O6S2; 55-98-1; MYLERANCytotoxic
H3CS
O[CH2]4
OO
OS
CH3
O O
Butacaine bü·ta·kän3-(Dibutylaminopropyl 4-aminobenzoate; C18H30N2O2; 149-16-6Butacaine Sulphate 149-15-5Local anaesthetic
H2N
O NBun2
O
Butafosfan bü·ta·fos·fan1-Butylamino-1-methylethylphosphinic acid; C7H18NO2P; 17316-67-5; ¨̈̈̈̈COFORTAPhosphorus source
P
O
H
C
Me
Me
BunHN OH
Butalamine bü·ta·la·mën2-(3-Phenyl-1,2,4-oxadiazol-5-ylamino)ethyldibutylamine; C18H28N4O; 22131-35-7Butalamine Hydrochloride LA 1221Vasodilator
N O
N NNBun
2
H
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1-85Butamirate (butamyrate) bü·ta·mi·rät
2-(2-Diethylaminoethoxy)ethyl 2-phenylbutyrate; C18H29NO3;18109-80-3Antitussive
H3C OO
O
NEt2H
and enantiomer
Butanilicaine bü·ta·ni·li·kän2-Butylamino-6¢-chloroaceto-o-toluidide; C13H19ClN2O; 3785-21-5Butanilicaine Phosphate HOSTACAIN*Local anaesthetic
NNHBun
Cl
Me
O
H
Butaprost bü·ta·prost(1) Methyl (E)-(11R,16R)-11,16-dihydroxy-9-oxo-16-(1-propylcyclobutyl)-17,18,19,20-tetranorprost-13-enoate; (2) methyl 7-{(1R,2R,3R)-3-hydroxy-2-[(1E,4R)-4-hydroxy-4-(1-propylcyclobutyl)but-1-enyl]-5-oxocyclopentyl)}heptanoate; C24H40O5; 69648-38-0; BAY q 4218Bronchodilator
COOMeO
HO
HHOCH3
H
H
Butaxamine (butoxamine) bü·taks·a·mën(±)-erythro-1-(2,5-Dimethoxyphenyl)-2-tert-butylaminopropan-1-ol; C15H25NO3;2922-20-5Inhibitor of fatty acid mobilisation
NHBut
MeO
OMe
H OH
H Me
and enantiomer
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1-86Butenafine bü·ten·a·fën
4-tert-Butylbenzyl(methyl)(1-naphthalenemethyl)amine; C23H27N;101828-21-1Butenafine Hydrochloride 101827-46-7; KP-363Antifungal
N
Bu tMe
Butetamate (butethamate) bü·te·ta·mät2-Diethylaminoethyl 2-phenylbutyrate; C16H25NO2; 14007-64-8Butetamate Citrate C·A·M·*Antispasmodic
H3C ONEt2
H
O
and enantiomer
�Buthalital Sodium (buthalitone sodium) bü·thal·i·tal sö·dë·umA mixture of 100 parts by weight of the monosodium derivative of 5-allyl-5-isobutyl-2-thiobarbituric acid and 6 parts by weight of dried sodium carbonate;510-90-7
Butikacin bü·tik·kä·sin6-O-(3-Amino-3-deoxy-a-D-glucopyranosyl)-4-O-(6-amino-6-deoxy-a-D-glucopyranosyl)-N1-[(2S)-4-amino-2-hydroxybutyl]-2-deoxy-D-streptamine;C22H45N5O12; 59733-86-7Antibacterial
NH2NH
OH
O
O
HO
NH2O
OH
OH
HO
NH2
O
H OH
H2N
HO
HO
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1-87Butirosin Sulphate (INNM) bü·ti·rö·sin
A mixture of the (1:2) sulfates of the A and B components of an antibioticproduced by Bacillus circularis; C21H41N5O12,2H2SO4; 12772-35-9Component A: 1-N-[(S)-4-Amino-2-hydroxybutyryl]-2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl)-5-O-(b-D-xylofuranosyl)streptamineComponent B: 1-N-[(S)-4-Amino-2-hydroxybutyryl]-2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl)-5-O-(b-D-ribofuranosyl)streptamine
NH2NH
OR
OH2N
OH
HO
NH2
O
O
H OH
H2N
HO
R =
OHOH
OHO
OH
OHO
OH
form A
form B
�Butobarbital (butobarbitone) bü·tö·bar·bi·tal5-Butyl-5-ethylbarbituric acid; C10H16N2O3; 77-28-1; SONERYLHypnotic
NH
N OO
O
EtBun
H
Butoconazole bü·tö·kon·a·zôl1-[4-(4-Chlorophenyl)-2-(2,6-dichlorophenylthio)butyl]imidazole; C19H17Cl3N2S;64872-76-0Butoconazole Nitrate 64872-77-1; RS-35887-00-10-3Antifungal
S
Cl
ClN
H
N
Cl
and enantiomer
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1-88Butorphanol bü·tor·fa·nol
(-)-9a-(Cyclobutylmethyl)morphinan-3,14-diol; C21H29NO2; 42408-82-2Butorphanol Tartrate 58786-99-5; ¨̈̈̈̈TORBUTROLOpioid analgesic
N
HO
HHO
Butoxamine see Butaxamine�Butriptyline bü·trip·ti·lën
3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-yl)-2-methylpropyl-dimethylamine; C21H27N; 15686-37-0Butriptyline Hydrochloride 5585-73-9Antidepressant
NMe2H Me
and enantiomer
�Butylated Hydroxyanisole (BAN) hï·droks·ë·a·ni·sôl2-tert-Butyl-4-methoxyphenol; C11H16O2; 25013-16-5Antioxidant
MeO
OHBut
�Butylated Hydroxytoluene (BAN) hï·droks·ë·tol·ü·ën2,6-Di-tert-butyl-p-cresol; C15H24O; 128-37-0Antioxidant
OHBut
ButMe
Cabergoline ka·ber·gö·lën(8R)-6-Allyl-N-[3-(dimethylamino)propyl]-N-(ethylcarbamoyl)ergoline-8-carboxamide; C26H37N5O2; 81409-90-7; CABASER; DOSTINEXDopamine D2-receptor agonist
HN
N
N NHEt
H
HCH2
O O
NMe2
H
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1-89Cadexomer¾¾¾¾¾ Iodine (INNM) ka·deks·o·mer
2-Hydroxytrimethylene cross-linked (1® 4)-a-D-glucan carboxymethylethercontaining iodine within the helix-structure; IODOSORBPromoter of wound healing
Cadralazine ka·dra·la·zënEthyl 3-{6-[ethyl(2-hydroxypropyl)amino]pyridazin-3-yl}carbazate; C12H21N5O3;64241-34-5; CGP 18684/E; ISF 2469Vasodilator
NN
NNHCOOEt
NH3C
EtHHO
H
and enantiomer
Cafedrine ka·fe·drën7-[2-(b-Hydroxy-a-methylphenethylamino)ethyl]theophylline; C18H23N5O3; 58166-83-9Analeptic
MeN
NN
N
NH
H Me
H OHO
O
Me
* *
mixture of 4 stereoisomers
�Caffeine (BAN) ka·fën3,7-Dihydro-1,3,7-trimethylpurine-2,6(1H)-dione; C8H10N4O2; 58-08-2;component in many proprietary preparationsCentral nervous system stimulant
N
N
N
O
O
Me
MeN
Me
�Calcifediol kal·si·fe·dï·ol(5Z,7E)-(3S)-9,10-Secocholesta-5,7,10(19)-triene-3,25-diol; calcidiol; C27H44O2;19356-17-3Vitamin D analogue
MeCH2
Me
HHO
MeH
Me
OHH
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1-90Calcipotriol kal·si·pö·trï·ol
(5Z,7E,22E)-(lS,3R,24S)-26,27-Cyclo-9,10-secocholesta-5,7,10(19),22-tetraene-1,3,24-triol; calcipotriene (USAN); C27H40O3; 112828-00-9; DOVONEXTreatment of psoriasis
OH
HO
MeH
MeH OHH
CH2
H
Calcitonin kal·si·tö·ninA polypeptide hormone of ultimobranchial origin, extractable from the thyroidgland of mammalian species or the ultimobranchial gland of non-mammals, thatlowers the calcium concentration in plasma of mammals; thyrocalcitonin;C145H240N44O48S2; 9007-12-9�Calcitonin (Pork) CALCITARE�Calcitonin (Salmon) / Salcatonin kal·si·tö·nin/sal·ka·tö·ninA component of natural salmon calcitonin produced synthetically;C145H240N44O48S2; 47931-85-1; CALSYNAR; MIACALCICCalcitonin analogueHypocalcaemic hormonecalcitonin (salmon) / salcatonin has the following amino acid sequence:
Cys_Ser_Asn_Leu_Ser_Thr_Cys_Val_
Leu_Gly_Lys_Leu_Ser_Gln_Glu_Leu_
His_Lys_Leu_Gln_Thr_Tyr_Pro_Arg_
Thr_Asn_Thr_Gly_Ser_Gly_Thr_Pro_NH2
�Calcitriol kal·si·trï·ol(1) (5Z,7E)-9,10-Secocholesta-5,7,10(19)-triene-1a,3b,25-triol;(2) 1a,25-dihydroxycholecalciferol; C27H44O3; 32222-06-3; CALCIJEX; ROCALTROLVitamin D analogue
OH
HO
MeH
MeH
CH2Me
Me
OH
H
�Calcium Benzamidosalicylate ben·za·mï·dö·sa·li·si·lätCalcium 4-benzamidosalicylate; benzoylpas calcium (USAN); C28H20CaN2O8; 528-96-1Antitubercular
N
OCOO
OHH
2
Ca
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1-91Calcium Folinate see Folinic Acid
Calcium Levofolinate kal·cë·um lë·vö·fö·li·nätCalcium N-{4-[(6S)-2-amino-5-formyl-1,4,5,6,7,8-hexahydro-4-oxopteridin-6-ylmethyl)amino]benzoyl}-L-glutamate; levoleucovorin calcium (USAN);C20H21CaN7O7; 80433-71-2; ISOVORIN
Antidote to folic acid antagonists; antineoplastic
Ca2+
N
N N
NN
N COO
H2N
CHO
O H COO
H
O
H
H
–
–
H H
Calcium Levulinate kal·së·um le·vü·li·nätCalcium 4-oxopentanoate; C10H14CaO6; 5743-49-7Calcium source
H3C COO_
O
Ca2+
2
Calcium Trisodium Pentetate pen·te·tätCalcium trisodium nitrilodiethylenedinitrilopenta-acetate; C14H18CaN3Na3O10 ;1317-31-3Chelating agent
NNCa
O OO O
NaOOCN COONa
COONa
Caldiamide Sodium (INNM) kal·dï·a·mïdSodium [6-carboxylatomethyl-3,9-bis(methylcarbamoylmethyl)-3,6,9-triazaundecanedioato-k3-N 3,N6,N 9-k3-O1,O6,O11(3-)calciate(II)];C16H26CaN5NaO8,xH2O; 122760-91-2Excipient in imaging enhancing agents
Na+.xH2O-
- -
NHMeO
MeHN
O O
O N
O ON NCa
O
O
2+
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1-92Calfactant (BAN) cal·fak·tant
An unmodified calf lung lavage extract mostly phospholipids and surfactant specificproteins (SP-B & SP-C)Treatment of respiratory distress syndrome
Calteridol Calcium (INNM) kal·te·ri·dolCalcium (RS)-bis{[10-(2-hydroxypropyl-kO)-1,4,7,10-tetra-azacyclododecane-1,4,7-triyltriacetato-O1,O4,O7,N1,N4,N7,N10(3-)]calciate(II)}; C34H58Ca3N8O14;121915-83-1; PROHANCE*Free radical scavenger
N N
N N
Ca
COO__
OOC
_OOC
CH3
OHH
2 +
and enantiomer
2
Ca2 +
Cambendazole kam·ben·da·zôlIsopropyl [2-(1,3-thiazol-4-yl)benzimidazol-5-yl]carbamate; C14H14N4O2S; 26097-80-3; ¨̈̈̈̈ASCAPILLA;Anthelmintic
S
NN
N
Ni PrO
OH
H
Candesartan kan·des·ar·tan2-Ethoxy-1-[2¢-(1H-tetrazol-5-yl)biphenyl-4-ylmethyl]-1H-benzimidazole-7-carboxylic acid; C24H20N6O3; 139481-59-7Candesartan Cilexetil 145040-37-5; AMIAS
Angiotensin-II receptor antagonist; antihypertensive
N
NN
HN
COOH
N
N O
H3C
Candicidin kan·di·sï·dinA mixture of heptaenes produced byStreptomyces griseus and other species ofStreptomyces; 1403-17-4 Antifungal
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1-93Candoxatril kan·doks·a·tril
cis-4-{1-[(S)-2-(Indan-5-yloxycarbonyl)-3-(2-methoxyethoxy)propyl]-cyclopentylcarbonylamino}cyclohexanecarboxylic acid; C29H41NO7;118785-03-8; UK-79,300Antihypertensive
HO
O
H
MeOO N H
H COOH
O
Candoxatrilat kan·doxs·a·tri·latcis-4-{1-[(S)-2-Carboxy-3-(2-methoxyethoxy)propyl]cyclopentylcarbonyl-amino}cyclohexanecarboxylic acid; C20H33NO7; 118783-94-1; UK-73,967Antihypertensive
HH
MeOO N H
H COOH
O
HOOC
Cangrelor kan·gre·lorN-6-[2-(Methylsulfanyl)ethyl]-2-[(3,3,3-trifluoro)propylsulfanyl)]adenosine 5´-b,g-µ-dichloromethylenetriphosphate; C17H25N5Cl2F3O12P3S2; AR-C69931XXADP receptor antagonist (P2T -receptor antagonist); antithrombotic
ON
NN
NOP
O
OPP
HOCl Cl
OO OHHO
OH OH
SCF3
HNS
CH3
OH
Cannabinol ka·na·bi·nol6,6,9-Trimethyl-3-pentyl-6H-dibenzo[b,d]pyran-1-ol; C21H26O2; 521-35-7
O
Me Me
HO
Me
CH3
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1-94Canrenoic Acid kan·re·nö·ik
17b-Hydroxy-3-oxo-17a-pregna-4,6-diene-21-carboxylic acid; C22H29KO4; 4138-96-9Potassium Canrenoate 2181-04-6; SPIROCTAN-MDiuretic
O
Me
H H
HOH
COOHMe
Capecitabine ka·pe·sï·ta·bën(1) Pentyl 1-[(5-deoxy-b-D-ribofuranosyl)-5-fluoro-2-oxo-1,2-dihydropyrimidin-4-yl]carbamate;(2) 5-fluoro-N4-(pentyloxycarbonyl)-5´-deoxycytosine; C15H22FNO6; 154361-50-9Antineoplastic
OMe
N
OH OH
NF
O
HN O
O
CH3
Capreomycin kap·rë·ö·mï·sinA mixture of antimicrobial peptides produced by Streptomyces capreolus; 11003-38-6�Capreomycin Sulphate 1405-37-4; CAPASTAT
Antibacterial
H
H
H
NH
NH
N
NH
ONH2
O
N
NO
NHO
N
OO
NH2
HN
H2N O
NH2
HH
R
H
NH2
H
Capreomycin R
OH1A
1B H
Capromab ka·prö·mabImmunoglobulin G1, anti-(human B lymphoma cell) (mouse monoclonal 7E11-C5.3g1-chain), disulfide with mouse monoclonal 7E11-C5.3 light chain, dimer; 151763-64-3Capromab Pendetide 145464-28-4Diagnostic
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1-95�Caproxamine
(E)-3¢-Amino-4¢-methylhexanophenone O-(2-aminoethyl)oxime; C15H25N3O;24047-16-3
H3C N
Me
NH2
ONH2
Captodiame kap·tö·dï·äm2-(4-Butylthiobenzhydrylthio)ethyldimethylamine; C21H29NS2; 486-17-9Anxiolytic
SNMe2
H
nBuS
and enantiomer
�Captopril kap·tö·pril1-[(2S)-3-Mercapto-2-methylpropionyl]-L-proline; C9H15NO3S;62571-86-2; SQ14225; ACEPRIL; ACEZIDE*; CAPOTEN; CAPOZIDE*Angiotensin-converting enzyme inhibitor
O
MeH
COOHH
NHS
Carabersat ka·ra·ber·satN-[(3R,4S)-6-Acetyl-3-hydroxy-2,2-dimethylchroman-4-yl]-4-fluorobenzamide;C20H20FNO4; 185122-82-1; SB-204269-EOAnticonvulsant; treatment of epilepsy
O
OHH
Me
Me
O NH
F
H
H3C
O
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1-96Caramiphen ka·ra·mi·fen
2-Diethylaminoethyl 1-phenylcyclopentane-1-carboxylate; C18H27NO2;77-22-5Anticholinergic
ONEt2
O
Carazolol ka·ra·zo·lol1-(Carbazol-4-yloxy)-3-isopropylaminopropan-2-ol; C18H22N2O2;57775-29-8; BM 51052Beta-adrenoceptor antagonist
HN
O NHPr iOHH
and enantiomer
Carbachol kar·ba·kol2-Carbamoyloxyethyltrimethylammonium chloride; C6H15ClN2O2;51-83-2; ISOPTO CARBACHOL*Cholinergic
NMe3OH2N
O
Cl+ _
Carbadox kar·ba·doksMethyl 3-(quinoxalin-2-ylmethylene)carbazate 1,4-dioxide; C11H10N4O4;6804-07-5Antibacterial
N
NO
CH NNHCOOMeO
�Carbamazepine kar·ba·mä·ze·pën5H-Dibenz[b,f]azepine-5-carboxamide; C15H12N2O; 298-46-4; TEGRETOLAnticonvulsant
N
CONH2
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1-97�Carbaryl (BAN) kar·ba·rïl
1-Naphthyl methylcarbamate; C12H11NO2; 63-25-2; CARYLDERM; CLINICIDE; ̈ DERASECT;DERBAC-C; ̈ FLEACARE; SULEO-C
Insecticide
O NHMe
O
Carbasalate Calcium kar·ba·sa·lät kal·së·umCalcium bis[2-(acetoxy)benzoate]—urea; carbaspirin calcium (USAN);C19H18CaN2O9; 5749-67-7Analgesic; anti-inflammatory; antipyretic
COO_
OAc
2H2N NH2
O.Ca2+
Carbenicillin kar·be·ni·si·lin(6R)-6-(2-Carboxy-2-phenylacetamido)penicillanic acid; C17H18N2O6S;4697-36-3�Carbenicillin Sodium 4800-94-6Antibacterial
N
NO
NaOOC H
O
S
H COONa
Me
Me
H HH
and enantiomer at C*
*
Carbenoxolone kar·be·noks·o·lön3b-(3-Carboxypropionyloxy)-11-oxo-olean-12-en-30-oic acid; C34H50O7; 5697-56-3�Carbenoxolone Sodium 7421-40-1; BIOPLEX; BIORAL; PYROGASTRONE*Treatment of peptic ulcer
H
Me
Me
Me Me
Me COOH
H
O
OO
COOH
HMeMe
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1-98Carbetocin kar·bë·tö·sin
2,1-Desamino-4,1-desthio-O4·2-methyl[1-homocysteine]oxytocin ;C45H69N11O12S; 37025-55-1Oxytocic
CH2•CH2•CH2•CO-Tyr(Me)-Ile-Gln-
Asn-Cys-Pro-Leu-Gly-NH2
�Carbidopa kar·bi·dö·pa(S)-3-(3,4-Dihydroxyphenyl)-2-hydrazino-2-methylpropionic acid; C10H14N2O4;28860-95-9; SINEMET*Dopa-decarboxylase inhibitor
HO
HO COOH
NHNH2Me
Carbifene (carbiphene) kar·bi·fën2-Ethoxy-N-methyl-N-[2-(N-methyl-N-phenethylamino)ethyl]-2,2-diphenyl-acetamide; C18H34N2O2; 15687-16-8Analgesic
N
EtO
O
Me
N
Me
�Carbimazole kar·bi·ma·zôlEthyl 3-methyl-2-thioxo-4-imidazoline-1-carboxylate; C7H10N2O2S;22232-54-8; NEO-MERCAZOLEAntithyroid
N
N
COOEt
S
Me
�Carbinoxamine kar·bi·noks·a·mën2-[4-Chloro-a-(2-pyridyl)benzyloxy]ethyldimethylamine; C16H19ClN2O;486-16-8Carbinoxamine Maleate 3505-38-2Histamine H1-receptor antagonist
N
ONMe2
Cl
H
and enantiomer
Carbiphene see Carbifene
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1-99�Carbocisteine kar·bö·sis·tän
S-Carboxymethyl-L-cysteine; C5H9NO4S; 2387-59-9; MUCODYNEMucolytic
SCOOH
HOOCNH2H
Carbocloral kar·bö·klor·ralEthyl (2,2,2-trichloro-1-hydroxyethyl)carbamate; C5H8Cl3NO3; 541-79-7Hypnotic
Cl3C NHCOOEt
H OH
and enantiomer
Carbofenotion (carbophenothion) kar·bö·fë·nö·tï·onS-4-Chlorophenylthiomethyl O,O-diethyl phosphorodithioate; C11H16ClO2PS3;786-19-6Insecticide
P
S
OEt
SS
Cl
OEt
Carbolonium Bromide see Hexcarbacholine
�Carbomer kar·bo·merA polymer of acrylic acid cross-linked with allyl sucrose; 54182-57-9; CARBOPOL934; GELTEARS; CARBOMIXPharmaceutical aid
Carbophenothion see Carbofenotion
�Carboplatin kar·bö·pla·tincis-Diammine(cyclobutane-1,1-dicarboxylato)platinum; C6H12N2O4Pt; 41575-94-4;PARAPLATINCytotoxic
PtO
OO
O
NH3
NH3
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1-100Carboprost kar·bö·prost
(1) (Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-(3S)-3-hydroxy-3-methyloct-1-enyl]cyclopentyl}hept-5-enoic acid; (2) (5Z,13E)-(9S,11R,15S)-9,11,15-trihydroxy-15-methylprosta-5,13-dienoic acid; C21H36O5; 35700-23-3Carboprost Trometamol 58551-69-2; HEMABATEInducer of uterine muscle contraction
CH3
HO
HO
COOH
OHMe
Carbromal kar·brö·mal(2-Bromo-2-ethylbutyryl)urea; C7H13BrN2O2; 77-65-6Hypnotic
H2N N
O O
CH3
CH3
Br
H
Carbutamide kar·bü·ta·mïd1-Butyl-3-sulfanilylurea; C11H17N3O3S; 339-43-5Hypoglycaemic
H2N
SN NHBun
OO O
H
Carbuterol kar·bü·te·rol[5-(2-tert-Butylamino-1-hydroxyethyl)-2-hydroxyphenyl]urea; C13H21N3O3; 34866-47-2Carbuterol Hydrochloride 34866-46-1; SK&F 40383-ABeta-adrenoceptor agonist
HO
NHH2N
O
NHBu tH OH
and enantiomer
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1-101�Carfecillin kar·fe·si·lin
(6R)-6-(2-Phenoxycarbonyl-2-phenylacetamido)penicillanic acid; C23H22N2O6S;27025-49-6Carfecillin Sodium carbenicillin phenyl sodium (USAN); 21649-57-0Antibacterial
N
NO
PhOOC H
O
S
H COOH
Me
Me
H HH
and enantiomer at C*
*
Carfenazine (carphenazine) kar·fe·na·zën1-(10-{3-[4-(2-Hydroxyethyl)piperazin-1-yl]propyl}phenothiazin-2-yl)propan-1-one; C24H31N3O2S; 2622-30-2Carfenazine Maleate 2975-34-0Antipsychotic
N
S
N
NOH
COEt
Carindacillin ka·rin·da·si·lin(6R)-6-(2-Indan-5-yloxycarbonyl-2-phenylacetamido)penicillanic acid;C26H26N2O6S; 35531-88-5Carindacillin Sodium carbenicillin indanyl sodium (USAN);26605-69-6; CP-15464-2Antibacterial
HO N
NO
Ph H
O
S
H COOH
Me
Me
H H
O
and enantiomer at C*
*
Carisoprodol ka·rï·sö·prö·dol2-Methyl-2-propyltrimethylene carbamate isopropylcarbamate; C12H24N2O4; 78-44-4; CARISOMASkeletal muscle relaxant
iPrHN O
O
OMe Prn
NH2
O
and enantiomer
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1-102�Carmellose kar·me·lös
A poly(carboxymethyl) ether of cellulose; carboxymethylcellulose; 9000-11-7;GLANDOSANE; LUBORANT�Carmellose Sodium 9004-32-4 ; ORABASE; ORAHESIVE�Carmellose Calcium 9050-04-8Pharmaceutical aid
Carmustine kar·mus·tën1,3-Bis(2-chloroethyl)-1-nitrosourea; C5H9Cl2N3O2; 154-93-8; BiCNUCytotoxic
ClN N
Cl
O
N OH
Carnidazole kar·nï·da·zôlO-Methyl [2-(2-methyl-5-nitroimidazol-1-yl)ethyl]thiocarbamate; C8H12N4O3S;42116-76-7; ¨̈̈̈̈ SPARTRIXAntiprotozoan (veterinary)
N
N
Me
HN OMe
S
NO2
Carperidine kar·pe·ri·dënEthyl 1-(2-carbamoylethyl)-4-phenylpiperidine-4-carboxylate; C17H24N2O3; 7528-13-4Antitussive
N
COOEt
CONH2
Carphenazine see Carfenazine
Carprofen kar·prö·fen2-(6-Chlorocarbazol-2-yl)propionic acid; C15H12ClNO2; 53716-49-7; ¨̈̈̈̈ZENECARPAnalgesic; anti-inflammatory
NCOOH
H Me
Cl
H
and enantiomer
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1-103Carsalam kar·sa·lam
(1) 1,3-Benzoxazine-2,4(3H)-dione; (2) O-carbamoylsalicylic acid lactam;C8H5NO3; 2037-95-8Analgesic
O
NH
O
O
�Carteolol kar·të·o·lol5-(3-tert-Butylamino-2-hydroxypropoxy)-3,4-dihydroquinolin-2(1H)-one;C16H24N2O3; 51781-06-7lCarteolol Hydrochloride 51781-21-6; TEOPTIC
Beta-adrenoceptor antagonist
and enantiomer
N
O
O
NHBut
H OH
H
Carticaine see Articaine
Carumonam ka·roo·mo·nam(Z)-(2-Amino-1,3-thiazol-4-yl){[(2S,3S)-2-carbamoyloxymethyl-4-oxo-1-sulfoazetidin-3-yl]carbamoyl}methyleneamino-oxyacetic acid; C12H14N6O10S2;87638-04-8; AMA 1080Carumonam Sodium 86832-68-0; AMA 1080(2Na)Antibacterial
H
S
N
N
O
N
N O COOH
O H
OCONH2HHO3S
H2N
Carvedilol kar·ve·di·lol1-Carbazol-4-yloxy-3-[2-(2-methoxyphenoxy)ethylamino]propan-2-ol;C24H26N2O4; 72956-09-3; EUCARDIC
Beta-adrenoceptor antagonist; vasodilator
NH
ONO
OHH
OMe
H
and enantiomer
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1-104Cefacetrile ke·fas·e·trïl
3-(Acetyloxy)methyl)-7-[(cyanoacetyl)amino]-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; C13H13N3O6S; 10206-21-0Cefacetrile Sodium 23239-41-0Antibacterial (veterinary)
N
S
OAc
COOH
H HN
O
NC
O
H
�Cefaclor (pINN) ke·fa·klor3-Chloro-7-(a-D-phenylglycylamino)-3-cephem-4-carboxylic acid; C15H14ClN3O4S;53994-73-3; DISTACLOR; KEFTIDAntibacterial
OO
N
NHH
S
Cl
COOH
H2N H H
�Cefadroxil (pINN) ke·fa·droks·il7-[a-D-(p-Hydroxyphenyl)glycylamino]-3-methyl-3-cephem-4-carboxylic acid;C16H17N3O5S; 50370-12-2; BAXAN; ¨̈̈̈̈CEFA-TABSAntibacterial
H2N H
Me
COOH
S
O
N NN
ON
HO
H
�Cefalexin (pINN) (cephalexin) ke·fa·leks·in3-Methyl-7-(a-D-phenylglycylamino)-3-cephem-4-carboxylic acid; C16H17N3O4S;15686-71-2 (anhydrous); 23325-78-2 (monohydrate); CEPOREX; KEFLEXAntibacterial
H2N
MeCOOH
S
O
H HNH
ON
H
Cefaloglycin (pINN) (cephaloglycin) ke·fa·lö·glï·sin7-(a-D-Phenylglycylamino)cephalosporanic acid; C18H19N3O6S;3577-01-3Antibacterial
H2N
COOH
S
O
H HNH
ON
H
OAc
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1-105Cefalonium (pINN) (cephalonium) ke·fa·lö·në·um
3-(4-Carbamoyl-1-pyridiniomethyl)-7-[(2-thienyl)acetamido]-3-cephem-4-carboxylate; C20H18N4O5S2; 5575-21-3; ¨̈̈̈̈CEPRAVIN; ¨̈̈̈̈CEPRAVIN DRY COW VAntibacterial
SHH
O
CONH2
COO
O
N
N
S
N
_
+
H
�Cefaloram (pINN) (cephaloram)7-(2-Phenylacetamido)cephalosporanic acid; C18H18N2O6S; 859-07-4
H
COOH
S
O
H HN
ON OAc
�Cefaloridine (pINN) (cephaloridine) ke·fa·lor·ri·dën3-(1-Pyridiniomethyl)-7-[(2-thienyl)acetamido]-3-cephem-4-carboxylate;C19H17N3O4S2; 50-59-9Antibacterial
NS
COO
SH H
N
NO
O+
H
_
Cefalotin (pINN) (cephalothin) ke·fa·lö·tin7-[(2-Thienyl)acetamido]cephalosporanic acid; C16H15N2NaO6S2; 153-61-7�Cefalotin Sodium 58-71-9Antibacterial
S
CH2OAc
COOH
NO
NHH
S
O
H
Cefamandole (pINN) (cephamandole) ke·fa·man·dôl7-D-Mandelamido-3-[(1-methyltetrazol-5-yl)thiomethyl]-3-cephem-4-carboxylic acid; C18H18N6O5S2; 34444-01-4Antibacterial
HN
O
HO H
Me
COOH
ON
HHS
NN
NN
S
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1-106Cefamandole Nafate (cephamandole nafate) ke·fa·man·dôl na·fät
Sodium 7-[(aR)-a-formyloxy(phenyl)acetamido]-3-[(1-methyltetrazol-5-yl)thiomethyl]-3-cephem-4-carboxylate; C19H17N6NaO6S2; 42540-40-9; KEFADOLAntibacterial
HN
O
Me
COONa
ON
HHS
NN
NN
S
OOH
Cefapirin (pINN) ke·fa·pi·rin7-[2-(4-Pyridylthio)acetamido]cephalosporanic acid; C17H17N3O6S2;21593-23-7Cefapirin Sodium 24356-60-3; BL-P1322Antibacterial
SH H
N
NO
O
COOH
OAc
S
NH
Cefatrizine (pINN) ke·fa·trï·zën7-[a-D-(p-Hydroxyphenyl)glycylamino]-3-(1H-1,2,3-triazol-4-ylthiomethyl)-3-cephem-4-carboxylic acid; C18H18N6O5S2; 51627-14-6; BL-S640Antibacterial
H
S
NH
NN
SH
N
NO
O
COOH
HO
H2N H H
Cefazedone ke·fä·ze·dön7-[2-(3,5-Dichloro-4-oxo-1-pyridyl)acetamido]-3-(5-methyl-1,3,4-thiadiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acid; C18H15Cl2N5O5S3;56187-47-4Cefazedone Sodium EMD 30087Antibacterial
H
S
S
NN
SH
N
NO
O
COOHMe
N
Cl
O
ClH
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1-107Cefazolin (pINN) (cephazolin) ke·fä·zö·lin
3-[(5-Methyl-1,3,4-thiadiazol-2-yl)thiomethyl]-7-(tetrazol-1-ylacetamido)-3-cephem-4-carboxylic acid; C14H14N8O4S3; 25953-19-9�Cefazolin Sodium 27164-46-1; KEFZOLAntibacterial
O
NH
OS
COOH
HHS
N S
NN Me
N
NNN
Cefdinir kef·di·neer7-{(2-Amino-1,3-thiazol-4-yl)-2-[(Z)-hydroxyimino]acetamido}-3-vinylcephem-4-carboxylic acid; C14H13N5O5S2; 91832-40-5; C1-983; FK 482Antibacterial
O
NH
OCOOH
HHS
NS
N
CH2
NOH
H2N
Cefempidone ke·fem·pi·dön7-[2-(2-Amino-1,3-thiazol-5-yl)-2-[(Z)-2-oxopyrrolidin-3-yloxyimino)]acetamido]-3-pyridiniomethyl-3-cephem-4-carboxylate; C22H21N7O6S2; 103238-57-9; GR50692; TA 5901Antibacterial
H
NH
NSN
ON
COO
SH H
N
NO
O
H2N
O
+
_
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1-108Cefepime kef·e·pëm
7-{(2-Amino-1,3-thiazol-4-yl)-2-[(Z)-methoxyimino]acetamido}-3-(1-methylpyrrolidiniomethyl)-3-cephem-4-carboxylate; C19H24N6O5S2;88040-23-7; BMY-28142Cefepime Hydrochloride (1:1); 123171-59-5 (monohydrate);BMY-28142 2HCl.H2OAntibacterial
N
S
O
H H
NMe
COO_
N
S
H2N
N
OMeN
O
H
+
�Cefetecol7-{2-(2-Amino-1,3-thiazol-4-yl)-2-[(Z)-(S)-a-carboxy-3,4-dihydroxy-benzyloxyimino]acetamido}-3-cephem-4-carboxylic acid; C20H17N5O9S2; 117211-03-7
NS
ON
SH H
NH
NO
O
H2N
OH
OH
HOOC
COOH
Cefixime ke·fiks·ëm7-{2-(2-Amino-1,3-thiazol-4-yl)-2-[(Z)-carboxymethoxyimino)]acetamido}-3-vinyl-3-cephem-4-carboxylic acid; C16H15N5O7S2; 79350-37-1; SUPRAXAntibacterial
O
NH
OCOOH
HHS
NS
N
CH2
NO
H2N
COOH
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1-109Cefodizime ke·fö·di·zëm
7-{2-(2-Amino-1,3-thiazol-4-yl)-2-[(Z)-methoxyimino]acetamido}-3-(5-carboxymethyl-4-methyl-1,3-thiazol-2-ylthiomethyl)-3-cephem-4-carboxylic acid; C20H20N6O7S4; 69739-16-8Cefodizime Sodium 86329-79-5 (2Na); TIMECEFAntibacterial
S
N
SCOOH
Me
NS
OMeN
SH H
N
NO
O
H2N COOH
H
Cefonicid ke·fo·ni·sid7-[(R)-Mandelamido]-3-(1-sulfomethyl-1H-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid; C18H18N6O8S3; 61270-58-4Cefonicid Sodium 61270-78-8; SK&F D-75073-Z2Antibacterial
S
N N
NN
SH H
N
NO
O
COOH
SO3HH OH H
Cefoperazone ke·fö·pe·ra·zön7-[N-(4-Ethyl-2,3-dioxopiperazin-1-ylcarbonyl)-L-2-(4-hydroxyphenyl)-glycylamino]-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid; C25H27N9O8S2; 62893-19-0; T-15 51; CP-52640(anhydrous); CP-52640-3 (dihydrate)Cefoperazone Sodium 62893-20-3; ¨̈̈̈̈PATHOCEFAntibacterial
S
N N
NN
SH H
N
NO
O
COOH
HN
OH
H
N O
EtNO
O
Me
H
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1-110Ceforanide ke·for·ra·nïd
7-[2-(a-Amino-o-tolyl)acetamido]-3-(1-carboxymethyl-1H-tetrazol-5-ylthiomethyl)-3-cephem-4-carboxylic acid; C20H21N7O6S2; 60925-61-3; BL-S786Antibacterial
H
S
N N
NN
SH H
N
NO
O
COOH
COOH
NH2
Cefotaxime ke·fö·taks·ëm(Z)-7-[2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]cephalosporanicacid; C16H17N5O7S2; 60846-21-1�Cefotaxime Sodium 64485-93-4; CLAFORANAntibacterial
S
N N
O
S
NO
NOMe
H2N
COOH
OAc
HHH
Cefotetan ke·fö·të·tan2-{4-[4-Carboxy-7-methoxy-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-3-cephem-7-ylcarbamoyl]-1,3-dithietan-2-ylidene}malonamic acid; C17H17N7O8S4;69712-56-7; YM 09330; ICI 156,834Antibacterial
H
S
N N
NN
SH
N
NO
O
COOH
Me
S
S
CONH2
HOOC OMe
Cefotiam ke·fö·tï·am7-[2-(2-Amino-1,3-thiazol-4-yl)acetamido]-3-[1-(2-dimethylaminoethyl)-1H-tetrazol-5-ylthiomethyl]-3-cephem-4-carboxylic acid; C18H23N9O4S3;61622-34-2; CGP 14221ECefotiam Hydrochloride 66309-69-1; SCE 963Antibacterial
H
S
N N
O
S
NOH2N
COOH
HH
NN
NN
S
NMe2
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1-111Cefoxazole (cephoxazole) ke·foks·a·zôl
7-(3-o-Chlorophenyl-5-methyl-1,2-oxazol-4-ylcarboxamido)cephalosporanic acid;C21H18ClN3O7S; 36920-48-6; ¨̈̈̈̈CEPOXILLIN CERATE*Antibacterial
O
NH
ON
Cl
Me
OOAc
COOH
HHS
N
Cefoxitin ke·foks·i·tin3-Carbamoyloxymethyl-7-methoxy-7-[2-(2-thienyl)acetamido]-3-cephem-4-carboxylic acid; C16H17N3O7S2; 35607-66-0�Cefoxitin Sodium 33564-30-6; MEFOXINAntibacterial
S
N
O
S
NO
COOH
O
HNH2O
OMeH
Cefpirome kef·pi·röm(Z)-7-[2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(6,7-dihydro-5H-cyclopenta[b]pyridiniomethyl)-3-cephem-4-carboxylate;C22H22N6O5S2; 84957-29-9Cefpirome Sulphate 98753-19-6; CEFROMAntibacterial
H
N
H2N
OO
N
NHH
S
COO
NOMe
SN
_
+
Cefpodoxime kef·pö·doks·ëm7-[(Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-methoxymethyl-3-cephem-4-carboxylic acid; C15H17N5O6S2; 80210-62-4Cefpodoxime Proxetil 87239-81-4; ORELOXAntibacterial
H
NS
OMeN
SH H
N
NO
O
H2N COOH
OMe
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1-112Cefprozil kef·prö·zil
7-(D-4-Hydroxyphenylglycylamino)-3-(prop-1-enyl)cephem-4-carboxylic acid;C18H19N3O5S; 121123-17-9; BMY-28100-03-800Antibacterial
HN
O
HH2N
HON
H H
O
S
COOH
CH3
Cefquinome kef·kwi·nöm7-[(Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(5,6,7,8-tetrahydroquinoliniomethyl)-3-cephem-4-carboxylate; C23H24N6O5S2;84957-30-2Cefquinome Sulphate 123766-80-3Antibacterial
N
H2N
OO
N
NHH
S
COO
NOMe
SN
H
+
_
�Cefradine (cephradine) kef·ra·dën7-(a-D-Cyclohexa-1,4-dienylglycylamino)-3-methyl-3-cephem-4-carboxylic acid;C16H19N3O4S; 38821-53-3; VELOSEFAntibacterial
O
N
O Me
COOH
HHS
N
H2N H H
�Cefsulodin kef·sü·lö·din3-(4-Carbamoylpyridiniomethyl)-7-[(2R)-2-phenyl-2-sulfoacetamido]-3-cephem-4-carboxylate; C22H20N4O8S2; 62587-73-9Cefsulodin Sodium 52152-93-9Antibacterial
NOO
N
NHH
S
COO
CONH2HHO3S H
+
_
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1-113Ceftazidime kef·ta·zi·dëm
7-[(Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(1-carboxy-1-methylethoxyimino)-acetamido]-3-(1-pyridiniomethyl)-3-cephem-4-carboxylate; C22H22N6O7S2; 72558-82-8; GR 20263; FORTUM; KEFADIMAntibacterial
NS
ON
SH H
N
NO
O
H2N COO
COOH
N
Me
Me
H
+
_
Ceftibuten kef·ti·bü·ten7-[2-(2-Amino-1,3-thiazol-4-yl)-4-carboxyisocrotonamido]-3-cephem-4-carboxylic acid; C15H14N4O6S2; 97519-39-6; CEDAXAntibacterial
NS
SH H
N
NO
O
H2N COOH
COOH
H
H
Ceftiofur kef·tï·ö·fûr7-[(Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-(2-furoylthiomethyl)-3-cephem-4-carboxylic acid; C19H17N5O7S3;80370-57-6; CM 31,916Ceftiofur Hydrochloride 103980-44-5; U-64279ACeftiofur Sodium 104010-37-9; U-64279EAntibacterial (veterinary)
H
O
O
SNS
OMeN
COOH
SH H
N
NO
O
H2N
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1-114�Ceftizoxime kef·ti·zoks·ëm
7-[(Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-cephem-4-carboxylic acid; C13H13N5O5S2; 68401-81-0Ceftizoxime Sodium 68401-82-1Antibacterial
O
N
OCOOH
HHS
NS
N
NOMe
H2N
Ceftriaxone kef·trï·aks·ön7-[(Z)-2-(2-Amino-1,3-thiazol-4-yl)-2-(methoxyimino)acetamido]-3-[(2,5-dihydro-6-hydroxy-2-methyl-5-oxo-1,2,4-triazin-3-yl)thiomethyl]-3-cephem-4-carboxylic acid; C18H18N8O7S3; 73384-59-5Ceftriaxone Sodium 104376-79-6; ROCEPHINAntibacterial
O
N
OCOOH
HHS
NS
N
NOMe
H2NS N
N
N
O
OH
Me
Cefuracetime ke·fûr·ra·se·tëm7-[(Z)-2-(2-Furyl)-2-(methoxyimino)acetamido]cephalosporanic acid;C17H17N3O8S; 39685-31-9; 640/1Antibacterial
O
N
OCOOH
HHS
NO
NOMe
OAc
H
Cefuroxime ke·fûr·roks·ëm3-Carbamoyloxymethyl-7-[(Z)-2-(2-furyl)-2-(methoxyimino)acetamido]-3-cephem-4-carboxylic acid; C16H16N4O8S; 55268-75-2�Cefuroxime Axetil 64544-07-6; ZINNATCefuroxime Pivoxetil 100680-33-9Cefuroxime Sodium 56238-63-2; ¨̈̈̈̈ SPECTRAZOL; ZINACEFAntibacterial
O
N
OCOOH
HHS
NO
NOMe
O NH2
O
H
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1-115Celecoxib se·lë·koks·ib
4-[5-p-Tolyl-3-(trifluoromethyl)pyrazol-1-yl]benzenesulfonamide; C17H14F3N3O2S;169590-42-5Cyclo-oxygenase-2 inhibitor
N
N
NH2S
OO
Me
CF3
Celiprolol se·li·pro·lol(RS)-3-{3-Acetyl-4-[3-(tert-butylamino)-2-hydroxypropoxy]phenyl}-1,1-diethylurea; C20H33N3O4; 56980-93-9Celiprolol Hydrochloride 57470-78-7; CELECTOLBeta-adrenoceptor antagonist
O
NEt2NCH3
O
O
H OHNHBu t
H
and enantiomer
�Cellacefate (cellacephate) se·la·së·fätAn approximately 75% esterified cellulose containing acetate and hydrogenphthalate groups in the ratio of 2:1; cellulose acetate phthalate (USP);9004-38-0Enteric coating
Celucloral se·lü·klor·ralHydroxyethylcellulose reaction product with chloral; ML 1034Hypnotic; anxiolytic
Cephalexin see Cefalexin
Cephaloglycin see Cefaloglycin
Cephalonium see Cefalonium
Cephaloram see Cefaloram
Cephaloridine see Cefaloridine
Cephalosporin C (BAN) ke·fa·lö·spor·rin7-(5-Amino-5-carboxypentanamido)cephalosporanic acid; C16H21N3O8S; 61-24-5Antibiotic
COOH
SH H
NH
NO
O OAc
H2N
H COOH
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1-116Cephalothin see Cefalothin
Cephamandole see Cefamandole
Cephamandole Nafate see Cefamandole Nafate
Cephazolin see Cefazolin
Cephoxazole see Cefoxazole
Cephradine see Cefradine
Cerivastatin se·ri·va·sta·tin(E)-(3R,5S)-7-[4-(4-Fluorophenyl)-2,6-di-isopropyl-5-methoxymethyl-3-pyridyl]-3,5-dihydroxyhept-6-enoic acid; C26H34FNO5Cerivastatin Sodium 143201-11-0; LIPOBAY
HMG-CoA reductase inhibitor; antihypercholesterolaemic
N
F
Pr i Pr i
HO HCOOH
H OH
MeO
Certoparin Sodium (certoparin) ser·to·pa·rinSodium salt of depolymerised heparin obtained by isoamyl nitrite-degradation ofheparin from pork intestinal mucosa; the majority of the components have a 2-O-sulfo-a-L-idopyranosuronic acid structure at the non-reducing end and a 6-O-sulfo-2,5-anhydro-D-mannose moiety at the reducing end of their chain; the molecularweight of 70% of the components is less than 10,000 and the average molecularweight is about 6000; the degree of sulfation is about 2 to 2·5 per disaccharideunit; ALPHAPARINAnticoagulant
Ceruletide se·roo·le·tïdC58H73N13O21S2; 17650-98-5Ceruletide Diethylamine 71247-25-1Diagnostic aid with cholecystokinin activity
5-oxoPro-Gln-Asp-Tyr-Thr-Gly-Trp-
Met-Asp-Phe-NH2
SO3H
Cetalkonium Chloride së·tal·kö·në·umBenzyl(hexadecyl)dimethylammonium chloride; C25H46ClN; 122-18-9; BONJELA*;TEEJEL*Anti-infective
NCH2
Me Me
CH2 CH314Cl+
_
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1-117Cetirizine se·ti·ri·zën
(RS)-2-[4-(4-Chlorobenzhydryl)piperazine-1-yl]ethoxyacetic acid; C21H25ClN2O3;83881-51-0�Cetirizine Hydrochloride (2HCl); 83881-52-1; ZIRTEKHistamine H1-receptor antagonist
N
NCl O COOH
H
and enantiomer
Cetomacrogol 1000 së·tö·ma·krö·golPolyethylene glycol 1000 monocetyl ether; polyoxyethylene glycol 1000 monocetylether; 9004-95-9Non-ionic surfactant
Cetoxime së·toks·ëm2-(N-Benzylanilino)acetamide oxime; C15H17N3O; 25394-78-9Histamine H1-receptor antagonist
NN
NH2
OH
�Cetrimide se·tri·mïdTrimethyl(tetradecyl)ammonium bromide together with smaller amounts ofdodecyl- and hexadecyl-trimethylammonium bromides; 8044-71-1; ¨̈̈̈̈CAPRITECT;CETAVLEX; ¨̈̈̈̈CETRIAD; CRADOCAP; ¨̈̈̈̈ STARCARE; ¨̈̈̈̈VANODINE; component inmany other proprietary preparationsAnti-infective
Cetrimonium Chloride (INNM) se·tri·mö·në·umHexadecyltrimethylammonium chloride; C19H42ClN; 57-09-0Anti-infective
H3C CH2 NMe315 Br+ _
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1-118Cetrorelix së·trö·rë·liks
[N-Acetyl-3-(2-naphthyl)]-D-alanyl-4-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-N5-carbamoyl-D-ornithyl-L-leucyl-L-arginyl-L-prolyl-D-alaninamide;C70H92ClN17O14; 120287-85-6Luteinising hormone-releasing hormone inhibitor;
N
H3CHN N
H
HN N
H
HN N
H
HN N
HO
O
O
OOH
O
O
O
NH
NH2O
O
H
Me Me
NH
NHHN
NH
NH2
O
O
H Me
H
H HO
H
H
OH
H
N
H
H
Cl
�Cetylpyridinium Chloride së·tïl·pi·ri·di·në·um1-Hexadecylpyridinium chloride; C21H38ClN; 123-03-5 (anhydrous);6004-24-6 (monohydrate); CALGEL*; MEROCAINE*; MEROCET; MEROTHOL;RIKOSPRAY; RINSTEAD*Anti-infective
CH2 CH314NCH2+
Cl_
Chenodeoxycholic Acid kë·nö·dë·oks·ë·kö·lik3a,7a-Dihydroxy-5b-cholan-24-oic acid; chenodiol (USAN); C24H40O4;474-25-9; CHENDOL; CHENOFALK; COMBIDOL*; LITHOFALKDissolution of cholesterol gallstones
HOH
H H
Me
Me
H
COOH
H
MeH
OH
Chlophedianol see Clofedanol
Chloral Betaine see Cloral Betaine
�Chloral Hydrate (BAN) klor·ral2,2,2-Trichloroethane-1,1-diol; C2H3Cl3O2; 302-17-0; NOCTEC; WELLDORM
Hypnotic
Cl
ClCl H
OH
OH
�Chloralodol (chlorhexadol) klor·ral·ö·dol2-Methyl-4-(2,2,2-trichloro-1-hydroxyethoxy)pentan-2-ol; C8H15Cl3O3; 3563-58-4Hypnotic
Cl3C O Me
MeOHMeHHHO
* *
mixture of 4 stereoisomers
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1-119�Chlorambucil klor·ram·bü·sil
4-{4-Bis(2-chloroethyl)amino]phenyl}butyric acid; C14H19Cl2NO2; 305-03-3;LEUKERANCytotoxic
COOH
NCl
Cl
Chloramine see Tosylchloramide Sodium
�Chloramphenicol klor·ram·fe·ni·kol2,2-Dichloro-N-[(aR,bR)-b-hydroxy-a-hydroxymethyl-4-nitrophenethyl]-acetamide;C11H12Cl2N2O5; 56-75-7; ACTINAC*; CHLOROMYCETIN;¨̈̈̈̈ INTRAMYCETIN; MINIMS CHLORAMPHENICOL; ¨̈̈̈̈OPTHAURAL*; ¨̈̈̈̈REOCETIN;¨̈̈̈̈ SENSICOL; SNO PHENICOL;�Chloramphenicol Palmitate 530-43-8; present as a component in many veteri-nary anti-infective preparations�Chloramphenicol Sodium Succinate 982-57-0; KEMICETINEAntibiotic
N
OHH
O2N
Cl
O
Cl
H
OH
H
Chlorbetamide klor·bë·ta·mïd2,2-Dichloro-N-(2,4-dichlorobenzyl)-N-(2-hydroxyethyl)acetamide;C11H11Cl4NO2; 97-27-8Antiprotozoan
N
Cl CHCl2
Cl
O
OH
Chlorbutol see Chlorobutanol
Chlorcyclizine klor·sï·kli·zën(RS)-1-(4-Chlorobenzhydryl)-4-methylpiperazine; C18H21ClN2; 82-93-9�Chlorcyclizine Hydrochloride 1620-21-9Histamine H1-receptor antagonist
N
NMeH
Cl
and enantiomer
Chlordantoin see Clordantoin
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1-120�Chlordiazepoxide klor·dï·ä·ze·poks·ïd
7-Chloro-2-methylamino-5-phenyl-3H-1,4-benzodiazepine 4-oxide; C16H14ClN3O;58-25-3; LIBRIUM�Chlordiazepoxide Hydrochloride 438-41-5
N
N
NHMe
ClO
Chlorfenvinphos see Clorfenvinfos
Chlorhexadol see Chloralodol
Chlorhexidine klor·heks·i·dën5,5¢-Bis(4-chlorophenyl)-1,1¢-hexamethylenebiguanide; C22H30Cl2N10;55-56-1; ¨̈̈̈̈NOLVASAN; ¨̈̈̈̈ SAVLON VETERINARY; ¨̈̈̈̈VETASEPT; salts of chlorhexidineare components of a large number of proprietary preparations�Chlorhexidine Acetate 56-95-1;�Chlorhexidine Gluconate 18472-51-0�Chlorhexidine Hydrochloride 3697-42-5Antibacterial
H H
Cl
N N
NH NH
NH
[CH2]4
H H
Cl
N N
NH NH
NH
Chlorisondamine Chloride klor·ï·son·da·mën4,5,6,7-Tetrachloro-2-methyl-2-(2-trimethylammonioethyl)isoindoliniumdichloride; C14H20Cl6N2; 69-27-2Hypotensive
2ClMe
N
Cl
Cl
Cl
Cl
NMe3+
+
_
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1-121Chlormadinone klor·mad·i·nön
6-Chloro-17a-hydroxypregna-4,6-diene-3,20-dione; C23H29ClO4;1961-77-9Chlormadinone AcetateProgestogen
O
Cl
Me
Me
H H
H
CH3O
OH
Chlormerodrin klor·me·rö·drin(RS)-Chloro(2-methoxy-3-ureidopropyl)mercury; C5H11ClHgN2O2;10375-56-1Diuretic
ClHg N NH2
MeO H
O
H
and enantiomer
Chlormethine / Mustine klor·me·thën / mus·tënBis(2-chloroethyl)methylamine; mechlorethamine (USAN); C5H11Cl2N; 51-75-2�Chlormethine Hydrochloride / Mustine Hydrochloride 55-86-7Cytotoxic
ClN
Cl
Me
Chlormethiazole see Clomethiazole
�Chlormezanone klor·me·za·nön2-(4-Chlorophenyl)-3-methyl-1,3-thiazinan-4-one 1,1-dioxide; C11H12ClNO3S; 80-77-3Anxiolytic
S
MeN
Cl
O
O O
�Chlormidazole1-(4-Chlorobenzyl)-2-methylbenzimidazole; C15H13ClN2; 3689-76-7
N
NMeCl
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1-122�Chlorobutanol (chlorbutol) klor·rö·bü·ta·nol
1,1,1-Trichloro-2-methylpropan-2-ol; C4H7Cl3O; 57-15-8 (anhydrous);6001-64-5 (hemihydrate); CERUMOL*; ELUDRIL MOUTHWASH*; FRADOL*;MONPHYTOL*Antimicrobial preservative
Cl3C OH
MeMe
Chloropyramine (halopyramine) hä·lö·pi·ra·mën2-[4-Chlorobenzyl(2-pyridyl)amino]ethyldimethylamine; C16H26ClN3; 59-32-5Histamine H1-receptor antagonist
NNMe2
NCl
Chloropyrilene klor·rö·pi·ri·lën2-[(5-Chloro-2-thenyl)(2-pyridyl)amino]ethyldimethylamine; C14H18ClN3S; 148-65-2Histamine H1-receptor antagonist
SN
N
NMe2Cl
Chloroquine klor·rö·kwën(RS)-4-(7-Chloro-4-quinolylamino)pentyldiethylamine; C18H26ClN3; 54-05-7�Chloroquine Phosphate 50-63-5; AVLOCHLOR�Chloroquine Sulphate 132-73-0; NIVAQUINEAntimalarial
NCl
HN
H MeNEt2
and enantiomer
�Chlorothiazide klor·rö·thï·a·zïd6-Chloro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; C7H6ClN3O4S2;58-94-6; SALURICDiuretic
SNH
N
OOS
H2N
OO
Cl
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1-123Chlorotrianisene klor·rö·trï·a·ni·sën
Chlorotris(4-methoxyphenyl)ethylene; C23H21ClO3; 569-57-3Oestrogen
Cl
OMeMeO
OMe
�Chloroxylenol klor·ro·zï·le·nol4-Chloro-3,5-xylenol; C8H9ClO; 88-04-0; DETTOL; RINSTEAD; ¨ ̈¨ ¨ ¨RYCOVETROXENTOL; ZEASORB*Antiseptic
OH
Cl
MeMe
�Chlorphenesin klor·fen·ë·sin(RS)-3-(4-Chlorophenoxy)propane-1,2-diol; C10H12ClNO4; 104-29-0Antifungal
O OH
Cl
H OH
and enantiomer
Chlorphenamine/Chlorpheniramine klor·fen·a·mën/klor·fe·ni·ra·mën(RS)-3-(4-Chlorophenyl)-3-(2-pyridyl)propyldimethylamine; C16H19ClN2; 132-22-9�Chlorphenamine Maleate/Chlorpheniramine Maleate 113-92-8; EXPULIN*;GALPSEUD PLUS*; HAYMINE*; PIRITON; ¨̈̈̈̈TELODRONHistamine H1-receptor antagonist
and enantiomer
N
Cl
NMe2H
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1-124Chlorphenoctium Amsonate klor·fe·nok·të·um
Bis[2,4-dichlorophenoxymethyldimethyl(octyl)ammonium]4,4¢-diaminostilbene-2,2¢-disulfonate; C31H41Cl2N3O5S2; 7168-18-5Antifungal
+
CH CH NH2H2N
SO3_ _
O3S
ClCl
O N [CH2]7 CH3
2
Me Me
Chlorphenoxamine klor·fe·noks·a·mën(RS)-2-[1-(4-Chlorophenyl)-1-phenylethoxy]ethyldimethylamine; C18H22ClNO;77-38-3Anticholinergic
ONMe2
Me
Cl
and enantiomer
Chlorphentermine klor·fen·ter·mën4-Chloro-a,a-dimethylphenethylamine; C10H14ClN; 461-78-9Appetite suppressant
Cl
Me
H2N Me
�Chlorproguanil klor·prö·gwa·nil1-(3,4-Dichlorophenyl)-5-isopropylbiguanide; C11H15Cl2N5; 537-21-3Antimalarial
Cl
Cl
N NMe
NH NH
H MeH H
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1-125�Chlorpromazine klor·prö·ma·zën
3-(2-Chlorophenothiazin-10-yl)propyldimethylamine; C17H19ClN2S;50-53-3�Chlorpromazine Hydrochloride 69-09-0; CHLORACTIL; LARGACTILAntipsychotic
N
S
Cl
NMe2
�Chlorpropamide klor·prö·pa·mïd1-(4-Chlorophenylsulfonyl)-3-propylurea; C10H13ClN2O3S; 94-20-2; DIABINESEHypoglycaemic
SN
OOO
Cl
NHPrn
H
Chlorprothixene klor·prö·thiks·ën(Z)-3-[2-Chloro(thioxanthen-9-ylidene)]propyldimethylamine; C18H18ClNS; 113-59-7�Chlorprothixene Hydrochloride 6469-93-8Antipsychotic
S
Cl
H NMe2
Chlorpyrifos (BAN) klor·pi·ri·fosO,O-Diethyl O-3,5,6-trichloro-2-pyridyl phosphorothioate; C9H11Cl3NO3PS; 2921-88-2Insecticide
P
S
OEt
O
N
Cl
Cl
Cl
OEt
Chlorquinaldol klor·kwi·nal·dol5,7-Dichloro-2-methylquinolin-8-ol; C10H7Cl2NO; 72-80-0; LOCOID C*Anti-infective
N Me
OH
Cl
Cl
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1-126�Chlortalidone (chlorthalidone) klor·ta·li·dön
(RS)-2-Chloro-5-(1-hydroxy-3-oxoisoindolin-1-yl)benzenesulfonamide;C14H11ClN2O4S; 77-36-1; HYGROTON; KALSPARE*; TENORET*; TENORETIC*Diuretic
and enantiomer
NH
SO2NH2
Cl
OH
O
Chlortetracycline klor·te·tra·sï·klën(4S,4aS,5aS,6S,12aS)-7-Chloro-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide; 7-chlorotetracycline; C22H23ClN2O8; 57-62-5�Chlortetracycline Hydrochloride 64-72-2; AUREOCORT*; ¨̈̈̈̈AUREOGRAN;AUREOMYCIN; ¨̈̈̈̈AUREOSUP; ¨̈̈̈̈AUROFAC; ¨̈̈̈̈AUROMIX; ¨̈̈̈̈CHLORSOL; ¨̈̈̈̈CYFAC*;DETECLO*; ¨̈̈̈̈MICROFAC*; ¨̈̈̈̈OMNISOL; ¨̈̈̈̈ P·E·P*·; ¨̈̈̈̈TARGOT*Antibacterial
OH O HO O
CONH2
OH
NMe2HH
MeHO
OH
Cl
Chlorthalidone see Chlortalidone
Chlorthenoxazine (chlorthenoxazin) klor·the·noks·a·zën2-(2-Chloroethyl)-2,3-dihydro-1,3-benzoxazin-4-one; C10H10ClNO2;132-89-8Analgesic; anti-inflammatory
O
NH
O
Cl
Chlorzoxazone klor·zoks·a·zön5-Chloro-1,3-benzoxazol-2(3H)-one; C7H4ClNO2; 95-25-0Skeletal muscle relaxant
O
NCl
O
H
Cholecalciferol see Colecalciferol
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1-127�Cholesterol (BAN) kö·le·ste·rol
Cholest-5-en-3b-ol; C27H46O; 57-88-5Pharmaceutical aid
Me
Me
HOH
H
HMe
MeH
HMe
Cholestyramine see Colestyramine
�Choline Salicylate kö·lën sa·li·si·lätCholine salt of salicylic acid; C12H19NO4; 2016-36-6; AUDAX; BONJELA; TEEJEL*Analgesic; antipyretic
OH
COO
HONMe3
+
_
�Choline Theophyllinate kö·lën thë·o·fi·li·nätCholine 1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-ide; oxtriphylline(USP); C12H21N5O3; 4499-40-5; CHOLEDYLBronchodilator
MeN
N
N_
O
O
Me
Me3NOH+
Choriogonadotropin Alfa ko·ri·ö·go·na·do·trö·pinHuman chorionic gonadotropin (protein moiety reduced), glycoform a, sub-units aand b; C437H682N122O134S13 (a sub-unit); C668H1090N196O203S13 (b sub-unit); 177073-44-8; 56832-30-5 (a sub-unit); 56832-34-9 (b sub-unit)Gonadotrophic hormone
APDVQDCPEC TLQENPFFSQ PGAPILQCMGCCFSRAYPTP LRSKKTMLVQ KNVTSESTCCVAKSYNRVTV MGGFKVENHT ACHCSTCYYHKS
SKEPLRPRCR PINATLAVEK EGCPVCITVNTTICAGYCPT MTRVLQGVLP ALPQVVCNYRDVRFESIRLP GCPRGVNPVV SYAVALSCQCALCRRSTTDC GGPKDHPLTC DDPRFQDSSSSKAPPPSLPS PSRLPGPSDT PILPQ
�-sub-unit
�-sub-unit
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1-128�Chorionic Gonadotrophin ko·ri·o·nik gon·a·dö·trö·fin
A preparation of a glycoprotein fraction secreted by the placenta and obtainedfrom the urine of pregnant women, having the action of the pituitary luteinisinghormone; 9002-61-3; ¨̈̈̈̈CHORULON; GONADOTRAPHON LH; HUMEGON; LH 1500;¨̈̈̈̈NYMFALON*; ¨̈̈̈̈ P·G· 600*; PROFASIGonadotrophic hormone
Chymopapain kï·mö·pa·pänA proteolytic enzyme isolated from papaya latex, differing from papainin electro-phoretic mobility, solubility and substrate specificity. The approximate molecularweight is 27,000; 9001-09-6Proteolytic enzyme
�Chymotrypsin kï·mö·trip·sinAn enzyme obtained from chymotrypsinogen by activation with trypsin;a-chymotrypsin; 9004-07-3; ZONULYSINProteolytic enzyme
Ciamexon sï·a·meks·on(RS)-1-(2-Methoxy-6-methyl-3-pyridylmethyl)aziridine-2-carbonitrile; C11H13N3O;75985-31-8; BM 41·332Immunoregulator
N
N
OMeMe
H
CN
and enantiomer
Cibenzoline sï·ben·zö·lën2-(2,2-Diphenylcyclopropyl)-2-imidazoline; cifenline (USAN); C18H18N2; 53267-01-9Cibenzoline Succinate cifenline succinate (USAN); 100678-32-8Antiarrhythmic
N
NH
�Ciclacillin sï·kla·si·lin(6R)-6-(1-Aminocyclohexanecarboxamido)penicillanic acid; C15H23N3O4S; 3485-14-1
NH
N
S
O
H H
OMe
Me
H COOH
H2N
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1-129Ciclazindol sï·kla·zin·dol
(RS)-10-(m-Chlorophenyl)-2,3,4,10-tetrahydropyrimido[1,2-a]indol-10-ol;C17H15ClN2O; 37751-39-6Ciclazindol Hydrochloride 37647-52-2; Wy 23409Antidepressant
N
NHO
Cl
and enantiomer
Cicletanine sï·kle·ta·nën(RS)-3-p-Chlorophenyl-1,3-dihydro-6-methylfuro[3,4-c]pyridin-7-ol;C14H12ClNO2; 89943-82-8Cicletanine Hydrochloride 82747-56-6Antihypertensive
O
N
OH
Me
Cl
H
and enantiomer
Ciclobendazole sï·klö·ben·da·zôlMethyl 5-(cyclopropylcarbonyl)benzimidazol-2-ylcarbamate; C13H13N3O3; 31431-43-3Anthelmintic
N
NNHCOOMe
O
H
Ciclopirox sï·klö·pï·roks6-Cyclohexyl-1-hydroxy-4-methyl-2-pyridone; C12H17NO2; 29342-05-0�Ciclopirox Olamine 41621-49-2Antifungal
N
OH
O
Me
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1-130Cicloprofen sï·klö·prö·fen
(RS)-2-(Fluoren-2-yl)propionic acid; C16H14O2; 36950-96-6; SQ 20824Analgesic; anti-inflammatory
COOH
H Me
and enantiomer
Cicloprolol (cycloprolol) sï·klö·prö·lol1-{4-[2-(Cyclopropylmethoxy)ethoxy]phenoxy}-3-(isopropylamino)propan-2-ol; C18H29NO4; 63659-12-1; SL 75 177-10Cicloprolol Hydrochloride 63686-79-3Beta-adrenoceptor antagonist
OO
O NHPriH OH
and enantiomer
Ciclosidomine sï·klö·si·do·mënN-Cyclohexylcarbonyl-3-morpholinosydnone imine; C13H20N4O3;66564-16-7Ciclosidomine Hydrochloride PR-G 138-CLVasodilator
N
N O
N N
O
O
+
_
Ciclotizolam sï·klö·tï·zö·lam2-Bromo-4-(2-chlorophenyl)-9-cyclohexyl-6H-thieno[3,2-f][1,2,4]triazolo[4,3-a][1,4]diazepine; C20H18BrClN4S; 58765-21-2; We 973-BSAnxiolytic
N
N
SBr
Cl
NN
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1-131Cicloxolone sï·kloks·o·lön
3b-(cis-2-Carboxycyclohexylcarbonyloxy)-11-oxo-18b-olean-12-en-30-oic acid;C38H56O7; 52247-86-6Treatment of gastric ulcers
H
Me
Me
Me Me
Me COOH
H
O
HMeMe
O
HOOC
O
* *
and epimer at C*
Cidofovir sï·dö·fo·veer1-[(S)-3-Hydroxy-2-(phosphonomethoxy)propyl]cytosine; C8H14N3O6P; 149394-66-1; VISTIDE
Antiviral
P
O
OH
OHO
OHH
NN
O
H2N
Ciladopa sï·la·dö·pa(S)-2-[4-(b-Hydroxy-3,4-dimethoxyphenethyl)piperazin-l-yl]cycloheptatrienone;C21H26N2O4; 80109-27-9Ciladopa Hydrochloride 83529-09-3; AY-27110Dopamine-receptor agonist
N
NOHH
OMe
OMe
O
Cilastatin sï·la·sta·tinS-{(Z)-6-Carboxy-6-[(S)-2,2-dimethylcyclopropanecarboxamido]hex-5-enyl}-L-cysteine; C16H26N2O5S; 82009-34-5Cilastatin Sodium 81129-83-1; PRIMAXIN*Dehydropeptidase inhibitor
Me
Me
OHNNH2H
COOHS
HOOC
H
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1-132Cilazapril sï·lä·za·pril
(1S,9S)-9-[(S)-1-Ethoxycarbonyl-3-phenylpropylamino]-10-oxoperhydropyridazino[1,2-a][1,2]diazepine-1-carboxylic acid; C22H31N3O5;88768-40-5; VASCASEAngiotensin-converting enzyme inhibitor
N
N
COOEtH
NHH
O H COOH
Cilazaprilat sï·lä·za·pri·latN-[1S,9S)-1-Carboxy-10-oxoperhydropyridazino[1,2-a][1,2]diazepin-9-yl]-4-phenyl-L-homoalanine; C20H27N3O5; 90139-06-3Angiotensin-converting enzyme inhibitor
N
N
COOHH
NHH
O H COOH
Cimetidine sï·me·ti·dën2-Cyano-1-methyl-3-[2-(5-methylimidazol-4-ylmethylthio)ethyl]guanidine;C10H16N6S; 51481-61-9; ALGITEC*; DYSPAMET; GALENAMET; PEPTIMAX;TAGAMET; ZITAHistamine H2-receptor antagonist
H
HN
NS
N
NCN
NHMe
Me
Cinchocaine sin·kö·kän2-Butoxy-N-(2-diethylaminoethyl)quinoline-4-carboxamide; C20H29N3O2; 85-79-0�Cinchocaine Hydrochloride 61-12-1; NUPERCAINAL; PROCTOSEDYL*;SCHERIPROCT*; ¨̈̈̈̈TERMINEZE*; ULTRAPROCT*; UNIROID*Local anaesthetic
N
NONEt2
OBun
H
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1-133Cinchophen sin·kö·fen
2-Phenylquinoline-4-carboxylic acid; C16H11NO2; 132-60-5;¨̈̈̈̈BUTA-LEUCOTROPIN*; ¨̈̈̈̈LEUCOTROPIN*; ¨̈̈̈̈ PREDNO-LEUCOTROPIN*Analgesic; anti-inflammatory
N
COOH
Cinepazet sï·ne·pä·zetEthyl 4-(3,4,5-trimethoxycinnamoyl)piperazin-1-ylacetate; C20H28N2O6; 23887-41-4Cinepazet Maleate 50679-07-7Vasodilator
N
N COOEt
O
OMe
MeO
MeO
Cinepazide sï·ne·pä·zïd1-(Pyrrolidin-1-ylcarbonylmethyl)-4-(3,4,5-trimethoxycinnamoyl)piperazine;C22H31N3O5; 23887-46-9Vasodilator
N
N
O
OMe
MeO
MeO
N
O
Cinfenoac sin·fe·nö·ak4-[2-(4-Carboxymethoxybenzoyl)vinyl]benzoic acid; C18H14O6;66984-59-6Cinfenoac Sodium BX 568AAnalgesic; anti-inflammatory
O
HOOC
O COOH
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1-134�Cinnarizine si·na·ri·zën
1-Benzhydryl-4-cinnamylpiperazine; C26H28N2; 298-57-7; STUGERONHistamine H1-receptor antagonist
N
N
H
H
Cinoxacin si·noks·a·sin1-Ethyl-1,4-dihydro-4-oxo-[1,3]dioxolo[4,5-g]cinnoline-3-carboxylic acid;C12H10N2O5; 28657-80-9; CINOBACAntibacterial
NN
O
O
O
COOH
Et
Cinoxolone si·noks·o·lönCinnamyl 3b-acetoxy-11-oxo-18b-olean-12-en-30-oate; C41H56O5;31581-02-9; BX 311Treatment of gastric ulcers
H
Me
Me
Me Me
Me
H
O
MeCOOH
MeMe
O
O
Ciprofibrate sï·prö·fi·brät2-[4-(2,2-Dichlorocyclopropyl)phenoxy]-2-methylpropionic acid; C13H14Cl2O3;52214-84-3; MODALIMHypolipidaemic
ClMeMe
COOHO
Cl
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1-135�Ciprofloxacin sï·prö·floks·a·sin
1-Cyclopropyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid; C17H18FN3O3; 85721-33-1�Ciprofloxacin Hydrochloride 86483-48-9; CILOXAN; CIPROXINCiprofloxacin Lactate CIPROXIN INFUSIONAntibacterial
HNN N
F COOH
O
�Cisapride sis·a·prïdcis-4-Amino-5-chloro-N-{1-[3-(4-fluorophenoxy)propyl]-3-methoxy-4-piperidyl}2-methoxybenzamide; C23H29ClFN3O4; 81098-60-4; ALIMIX; PREPULSIDIncrease of gastro-intestinal motility
NH
N O
O
F
OMe
Cl
H2N
H OMeH
and enantiomer
Cisatracurium Besilate sis·a·tra·kür·rë·um(1R,1¢R,2R,2¢R)-2,2¢-(3,11-Dioxo-4,10-dioxatridecamethylene)bis=(1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-1-veratrylisoquinolinium)dibenzenesulfonate; C65H82N2O18S2; 96946-42-8; NIMBEX
Non-depolarising neuromuscular blocker; muscle relaxant
MeN O
OMeO
MeO
MeOMeO
H
OMeOMe
OMe
OMeO
NOMe H
[ CH2] 5
SO3_
2
+ +
�Cisplatin sis·pla·tincis-Diamminedichloroplatinum; Cl2H6N2Pt; 15663-27-1Cytotoxic
PtCl
Cl
NH3
NH3
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1-136Citalopram sï·ta·lö·pram
1-(3-Dimethylaminopropyl)-1-(4-fluorophenyl)-1,3-dihydroisobenzofuran-5-carbonitrile; C20H21FN2O; 59729-33-8Citalopram Hydrobromide 59729-32-7; CIPRAMILAntidepressant
NCO
NMe2
Fand enantiomer
Cladribine kla·dri·bën2-Chloro-2¢-deoxyadenosine; C10H12ClN5O3; 4291-63-8; LEUSTAT
Antineoplastic
N
N
N
N
HO
OH
O
NH2
Cl
Clamidoxic Acid kla·mi·doks·ik[2-(3,4-Dichlorobenzamido)phenoxy]acetic acid; C15H11Cl2NO4;6170-69-0; SNR 1804Antirheumatic
N
O
ClO COOH
Cl
H
Clamoxyquine (clamoxyquin) kla·moks·ë·kwën5-Chloro-7-(3-diethylaminopropylaminomethyl)quinolin-8-ol; C17H24ClN3O; 2545-39-3Clamoxyquine Hydrochloride 4724-59-8; CI 443Antipotozoan
HEt2N N
NOH
Cl
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1-137Clarithromycin kla·ri·thrö·mï·sin
(2R,3S,4S,5R,6R,8R,10R,11R,12S,13R)-3-(2,6-Dideoxy-3-C,3-O-dimethyl-a-L-ribo-hexopyranosyloxy)-11,12-dihydroxy-6-methoxy-2,4,6,8,10,12-hexamethyl-9-oxo-5-(3,4,6-trideoxy-3-dimethylamino-b-D-xylo-hexopyranosyloxy)pentadecan-13-olide; C38H69NO13; 81103-11-9; KLARICIDAntibiotic
O
O
Me
OMe
Me
HO
O
O
OH
Me
NMe2
O
Me
Me
MeOMe
O
Me
HO
HOMe
Et
O
Me
Clavulanic Acid kla·vü·la·nik(Z)-(2R,5R)-3-(2-Hydroxyethylidene)-7-oxo-4-oxa-1-azabicyclo[3.2.0]heptane-2-carboxylic acid; C8H9NO5; 58001-44-8Potassium Clavulanate AUGMENTIN*; ¨̈̈̈̈ SYNULOX*; TIMENTIN*Beta-lactamase inhibitor
N
O
OH COOH
H
H
CH2OH
Clazuril kla·zûr·ril(RS)-4-Chlorophenyl[2-chloro-4-(2,3,4,5-tetrahydro-3,5-dioxo-1,2,4-triazin-2-yl)phenyl]acetonitrile; C17H10Cl2N4O2; 101831-36-1; ¨̈̈̈̈APPERTEXCoccidiostat
N
N
NHCl
CNH Cl
O
Oand enantiomer
Clebopride kle·bö·prïd4-Amino-N-(1-benzylpiperidin-4-yl)-5-chloro-2-methoxybenzamide; C20H24ClN3O2;55905-53-8Anti-emetic
NH
NO
OMe
Cl
H2N
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1-138Clefamide kle·fa·mïd
2,2-Dichloro-N-(2-hydroxyethyl)-N-[4-(4-nitrophenoxy)benzyl]acetamide;C17H16Cl2N2O5; 3576-64-5Antiprotozoan
O
Cl
OCl
OHN
O2N
Clemastine kle·mas·tën(2R)-2-{2-[(R)-4-Chloro-a-methylbenzhydryloxy]ethyl}1-methylpyrrolidine;C21H26ClNO; 15686-51-8�Clemastine Fumarate 14976-57-9; ALLER-EZE; TAVEGILHistamine H1-receptor antagonist
O
MeMeN
H
Cl
Clemeprol kle·me·prol1-(3-Chlorophenyl)-3-dimethylamino-l-phenylpropan-2-ol; C17H20ClNO; 71827-56-0Clemeprol Hydrochloride BRL 14342Antidepressant
Cl
NMe2H
HO
H*
*
mixture of 4 stereoisomers
�Clemizole kle·mi·zôl1-(4-Chlorobenzyl)-2-(pyrrolidin-1-ylmethyl)benzimidazole; C19H20ClN3;442-52-4Histamine H1-receptor antagonist
N
NN
Cl
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1-139�Clemizole Penicillin
1-(1-p-Chlorobenzylbenzimidazol-2-ylmethyl)pyrrolidinium (6R)-6-(2-phenylacetamido)penicillanate; C19H21ClN3·C16H17N2O4S; 6011-39-8Antibacterial
N
N HN
Cl
COO_
CH3
CH3
O
HHS
NO
NH+
Clenbuterol klen·bü·te·rol1-(4-Amino-3,5-dichlorophenyl)-2-tert-butylaminoethanol; C12H18Cl2N2O; 37148-27-9Clenbuterol Hydrochloride 21898-19-1; ¨̈̈̈̈ PLANIPART; ¨̈̈̈̈VENTIPULMINBeta-adrenoceptor agonist
H2N
Cl
ClH OH
NHBu t
and enantiomer
Clenpyrin (BAN) klen·pï·rinN-(1-Butylpyrrolidin-2-ylidene)-3,4-dichloroaniline; C14H18Cl2N2;27050-41-5Insecticide
N N
Bun
Cl
Cl
Cletoquine kle·tö·kwën2-{N-[4-(7-Chloro-4-quinolylamino)pentyl]amino}ethanol; C16H22ClN3O; 4298-15-1Analgesic; anti-inflammatory
and enantiomer
N MeH
OH
HN
Cl
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1-140Clidinium Bromide klï·di·në·um
3-Benziloyloxy-1-methylquinuclidinium bromide; C22H26BrNO3;3485-62-9;Anticholinergic
O
Me
N
HO
OBr
+ _
Climbazole klim·ba·zôl1-(4-Chlorophenoxy)-1-(imidazol-1-yl)-3,3-dimethylbutan-2-one; C15H17ClN2O2;38083-17-9; BAY e 6975; MEB 6401Antifungal; treatment of seborrhoea
N
N
CMe3O
Cl
H
O
and enantiomer
Clindamycin klin·da·mï·sinMethyl 7-chloro-6,7,8-trideoxy-6-[(2S,4R)-1-methyl-4-propylprolylamino]-1-thio-L-threo-D-galacto-octopyranoside; (7S)-chloro-7-deoxylincomycin; C18H33ClN2O5S;�Clindamycin Hydrochloride 21462-39-5; ¨̈̈̈̈ANTIROBE; DALACIN C�Clindamycin Palmitate Hydrochloride 25507-04-4; DALACIN CPAEDIATRIC�Clindamycin Phosphate 24729-96-2; DALACIN C PHOSPHATEAntibacterial
OHOHO
SMe
CONHCH
HCCl
CH3
OH
N
H
H
Me
Prn
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1-141�Clioquinol klï·ö·kwi·nol
5-Chloro-7-iodoquinolin-8-ol; iodochlorhydroxyquin; C9H5ClINO;130-26-7; BETNOVATE-C*; C*; LOCORTEN-VIOFORM*; QUINABAND*; SYNALAR C*;VIOFORM-HYDROCORTISONE*Antibacterial; antiprotozoan
N
OH
Cl
I
Clioxanide klï·oks·a·nïd2-(4-Chlorophenylcarbamoyl)-4,6-di-iodophenyl acetate; C15H10ClI2NO3; 14437-41-3Anthelmintic
N
ClO
OAc
I
I
H
�Clobazam klö·ba·zam7-Chloro-1,5-dihydro-1-methyl-5-phenyl-1,5-benzodiazepine-2,4(3H)-dione;C16H13ClN2O2; 22316-47-8; FRISIUMAnxiolytic; anticonvulsant
N
NCl
OMe
O
Clobetasol klö·bë·ta·sol21-Chloro-9a-fluoro-11b,17a-dihydroxy-16b-methylpregna-1,4-diene-3,20-dione; C22H28ClFO4; 25122-41-2�Clobetasol Propionate 25122-46-7; DERMOVATE; DERMOVATE-NN*Corticosteroid
O
Me
F H
H
HOMe
MeOH
ClO
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1-142Clobetasone klö·bë·ta·sön
21-Chloro-9a-fluoro-17a-hydroxy-16b-methylpregna-1,4-diene-3,11,20-trione; C22H26ClFO4; 54063-32-0�Clobetasone Butyrate 25122-57-0; CLOBURATE; EUMOVATE; TRIMOVATE*Corticosteroid
O
Me
F H
H
OMe
MeOH
ClO
Clobuzarit klö·bü·za·rit2-(4¢-Chlorobiphenyl-4-ylmethoxy)-2-methylpropionic acid; C17H17ClO3; 22494-47-9; ICI 55897Antirheumatic
O COOH
Cl
Me Me
Clociguanil klö·si·gwa·nil1-(3,4-Dichlorobenzyloxy)-1,2-dihydro-2,2-dimethyl-1,3,5-triazine-4,6-diyldiamine; C12H15Cl2N5O; 3378-93-6Antimalarial
N
N
NO
Cl
Cl
H2N
NH2
MeMe
Clodantoin (chlordantoin) klö·dan·tö·in5-(1-Ethylpentyl)-3-(trichloromethylthio)hydantoin; C11H17Cl3N2O2S;5588-20-5Antifungal
N
HNH3C
H EtO
SCCl3
O
**
mixture of 4 stereoisomers
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1-143Clodronic Acid klö·dro·nik
(Dichloromethylene)bisphosphonic acid; CH4Cl2O6P2; 10596-23-3Sodium Clodronate (2Na) 22560-50-5; BONEFOS; LORONAntiosteoclastic
P
O
OH
OHP
O
OH
HO C
Cl
Cl
�Clofazimine klö·fa·zi·mën3-(4-Chloroanilino)-10-(4-chlorophenyl)-2,10-dihydrophenazin-2-ylideneisopropylamine; C27H22Cl2N4; 2030-63-9; LAMPRENEAntileprotic
N
N N
Cl
Cl
NPri
H
Clofedanol (chlophedianol) klö·fe·da·nola-Chlorophenyl-a-(2-dimethylaminoethyl)benzyl alcohol; C17H20ClNO; 791-35-5Clofedanol HydrochlorideAntitussive
NMe2
Cl
OH
and enantiomer
Clofenvinfos (chlorfenvinphos) klö·fen·vin·fos2-Chloro-1-(2,4-dichlorophenyl)vinyl diethyl phosphate; C12H14Cl3O4P;470-90-6; ̈ COOPER'S MD POWDER DIP; ̈ POWERPACK; ̈ FLY DIP
Insecticide
OEt
Cl
Cl
Cl
O
OEt
O
P
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1-144�Clofibrate klö·fib·rät
Ethyl 2-(4-chlorophenoxy)-2-methylpropionate; C12H15ClO3; 637-07-0; ATROMID-SHypolipidaemic
Cl
O COOEt
Me Me
Clofluperol klö·floo·pe·rol4-[4-(4-Chloro-3-trifluoromethylphenyl)-4-hydroxypiperidino)]-4¢-fluorobutyrophenone; seperidol (USAN); C22H22ClF4NO2; 10457-91-7Antipsychotic
N
Cl
F3CHO
F
O
Clogestone klö·jes·tön6-Chloro-3b,17a-dihydroxypregna-4,6-diene-20-one; C25H33ClO5;20047-75-0Progestogen
Me
Me
H
H H
HO
Cl
MeO
OH
Cloguanamile (BAN) klö·gwa·na·mïl1-Amidino-3-(3-chloro-4-cyanophenyl)urea; C9H8ClN5O; 21702-93-2Antimalarial
HN
HN NH2
Cl
NCO NH
Clomacran klö·ma·kran3-(2-Chloro-9,10-dihydroacridin-9-yl)propyldimethylamine; C18H21ClN2; 5310-55-4Tranquilliser
HN
NMe2
H
Cl
and enantiomer
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1-145�Clomethiazole (chlormethiazole) klö·me·thï·a·zôl
5-(2-Chloroethyl)-4-methyl-1,3-thiazole; C6H8ClNS; 533-45-9; HEMINEVRINCAPSULESClomethiazole Edisilate 1867-58-9; HEMINEVRINHypnotic
N
S
Me
Cl
Clomifene (clomiphene) klö·mi·fën2-[p-(2-Chloro-1,2-diphenylvinyl)phenoxy]diethylamine; C26H28ClNO;911-45-5�Clomifene Citrate 50-41-9; CLOMID; SEROPHENEOestrogen-receptor antagonist
OCl NEt2
Clomipramine klö·mi·pra·mën3-(3-Chloro-10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)propyldimethylamine;C19H23ClN2; 303-49-1�Clomipramine Hydrochloride 17321-77-6; ANAFRANILAntidepressant
N
NMe2
Cl
�Clomocycline klö·mö·sï·klën(1) (4S,4aS,5aS ,6S,12aS)-7-Chloro-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-N-hydroxymethyl-6-methyl-1,11-dioxonaphthacene-2-carboxamide; (2) 7-chloro-2-N-(hydroxymethyl)tetracycline;C23H25ClN2O9; 1181-54-0Antibacterial
OH O HO O
OH
NMe2HH
MeHO
OH
Cl
N
O OH
H
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1-146�Clonazepam klö·nä·ze·pam
5-(2-Chlorophenyl)-1,3-dihydro-7-nitro-1,4-benzodiazepin-2-one; C15H10ClN3O3;1622-61-3; RIVOTRILAnticonvulsant
N
NO2N
O
Cl
H
Clonidine klo·ni·dën2,6-Dichloro-N-imidazolidin-2-ylideneaniline; C9H9Cl2N3; 4205-90-7�Clonidine Hydrochloride 4205-91-8 CATAPRES; DIXARITAlpha2-adrenoreceptor agonist
NH
NN
Cl
Cl
H
Clonitazene klö·nï·ta·zën2-(2-p-Chlorobenzyl-5-nitrobenzimidazol-1-yl)ethyldiethylamine; C20H23ClN4O2;3861-76-5Opioid analgesic
N
N
O2N
NEt2
Cl
Clopamide klö·pa·mïd4-Chloro-N-(cis-2,6-dimethylpiperidino)-3-sulfamoylbenzamide; C14H20ClN3O3S;636-54-5; VISKALDIX*Diuretic
NN
Cl
H2 NO2 S
OMe
H
H MeH
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1-147Clopenthixol klö·pen·thiks·ol
2-{4-[3-(2-Chloro-10H-dibenzo[b,e]thiin-10-ylidene)propyl]piperazin-1-yl}ethanol; C22H25ClN2OS; 982-24-1Antipsychotic
N
NOH
Cl
S
Clopidogrel klö·pi·dö·grelMethyl (S)-2-chlorophenyl(4,5,6,7-tetrahydrothieno[3,2-c]pyridin-5-yl)acetate; C16H16ClNO2S; 94188-84-8; SR 25990 CClopidogrel Sulphate PLAVIXPlatelet aggregation inhibitor
N
S
Cl H COOMe
Clopidol klö·pi·dol3,5-Dichloro-2,6-dimethylpyridin-4-ol; C7H7Cl2NO; 2971-90-6; ¨̈̈̈̈COYDENAntiprotozoan
N Me
Cl
OH
Cl
Me
Clopirac klö·pi·rak(1-p-Chlorophenyl-2,5-dimethylpyrrol-3-yl)acetic acid; C14H14ClNO2; 42779-82-8Analgesic; anti-inflammatory
N
Cl
Me
COOH
Me
Cloponone klö·po·nön(RS)-2,2-Dichloro-N-[4-chloro-a-(chloromethyl)phenacyl]acetamide;C11H9Cl4NO2; 15301-50-5Anti-infective
Cl
HN
Cl
O
Cl
HO
Cl
and enantiomer
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1-148Cloprednol klö·pred·nol
6-Chloro-11b,17a,21-trihydroxypregna-1,4,6-triene-3,20-dione; C21H25ClO5; 5251-34-3; RS 4691Corticosteroid
H
Me
H
HO
Me
H
Cl
O
O
OH
OH
Cloprostenol klö·prost·e·nol(1) (±)-(Z)-7-{(1R,2R,3R,5S)-2-[(E)-(3R)-4-(3-Chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl}hept-5-enoic acid;(2) (±)-(5Z, 13E)-(9S,11R,15R)-16-(3-chlorophenoxy)-9,11,15-trihydroxy-w-tetranorprosta-5,13-dienoic acid; C22H29ClO6; 40665-92-7�Cloprostenol Sodium 55028-72-3; ¨̈̈̈̈ESTRUMATE; ¨̈̈̈̈PLANATEProstanoid luteolytic
O
H
H OHHHO
COOH
HO
Cl
and enantiomer
Cloquinate klö·kwi·nätChloroquine bis(8-hydroxy-7-iodoquinoline-5-sulfonate);C18H26ClN3·(C9H6INO4S)2; 7270-12-4; COMPOSITUM*Antiprotozoan
N
OH
SO3H
INCl
HN
H MeNEt2
and enantiomer
2
,
Cloral Betaine (chloral betaine) klor·ral bë·tänChloral hydrate—betaine adduct; C7H14Cl3NO4; 2218-68-0; SOMILANHypnotic
Cl
ClCl H
OH
OHMeN COO
+ _
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1-149Clorazepic Acid (BAN) klor·ra·zë·pik
7-Chloro-2,3-dihydro-2-oxo-5-phenyl-1H-1,4-benzodiazepine-3-carboxylic acid;C16H11ClN2O3; 20432-69-3�Dipotassium Clorazepate (potassium clorazepate) 7109-90-7; TRANXENE
Hypnotic; anxiolytic
N
NCl
O
COOH
H
*
and enantiomer
�Clorexolone klor·reks·o·lön6-Chloro-2-cyclohexyl-3-oxoisoindoline-5-sulfonamide; C14H17ClN2O3S; 2127-01-7Diuretic
N
H2 NO2 S
Cl
O
Clorgiline (clorgyline) klor·jï·lën3-(2,4-Dichlorophenoxy)propyl(methyl)(prop-2-ynyl)amine; C13H15Cl2NO; 17780-72-2Monoamine oxidase inhibitor
N
MeCH
O
Cl
Cl
Clorindione klor·in·dï·ön2-(4-Chlorophenyl)indan-1,3-dione; C15H9ClO2; 1146-99-2Anticoagulant
ClO
O
Clorprenaline klor·pren·a·lën1-(2-Chlorophenyl)-2-isopropylaminoethanol; C11H16ClNO; 3811-25-4Beta adrenoceptor agonist
NHPr iH OH
Cl
and enantiomer
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1-150Clorsulon klor·sü·lon
4-Amino-6-(trichlorovinyl)benzene-1,3-disulfonamide; C8H8Cl3N3O4S2; 60200-06-8;¨ IVOMEC-F*Antiparasitic; fasciolicide
SO2NH2
SO2NH2
NH2
Cl
Cl
Cl
Closantel klö·san·tel5¢-Chloro-4¢-(4-chloro-a-cyanobenzyl)-3,5-di-iodosalicyl-o-toluidide;C22H14Cl2I2N2O2; 57808-65-8Closantel Sodium 61438-64-0; ¨̈̈̈̈FLUKIVER; ¨̈̈̈̈ SUPAVERM*Anthelmintic (veterinary)
N
CNH
O
Cl
Cl
MeOH
I
I
H
and enantiomer
Clostebol Acetate (INNM) klo·ste·bol a·së·tät4-Chloro-3-oxoandrost-4-en-17b-yl acetate; C19H27ClO2; 1093-58-9Anabolic steroid; androgen
O
Cl
Me
H
H
H
MeOAc
H
Clotiapine (clothiapine) klö·tï·a·pën2-Chloro-11-(4-methylpiperazin-1-yl)dibenzo[b,f][1,4]thiazepine; C18H18ClN3S;2058-52-8Antipsychotic
N
S
Cl
N
NMe
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1-151Cloticasone klö·tï·ka·sön
S-Chloromethyl 6a,9a-difluoro-11b,17a-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17b-carbothioate; C25H31ClF2O5S; 87556-66-9Cloticasone Propionate 80486-69-7; CCl 18773Corticosteroid
HF
Me
HMe
O
HO
O S
Me
F
OH
Cl
�Clotrimazole klö·tri·ma·zôl1-(2-Chlorotrityl)imidazole; C22H17ClN2; 23593-75-1; CANESTEN; LOTRIDERM*;MASNODERMAntifungal
N
N
Cl
Cloxacillin kloks·a·si·lin(6R)-6-(3-o-Chlorophenyl-5-methyl-1,2-oxazole-4-carboxamido)penicillanic acid;C19H18ClN3O5S; 61-72-3; ¨̈̈̈̈LACTACLOX*; ¨̈̈̈̈NOROCLOX�Cloxacillin Benzathine 32222-55-2; ¨̈̈̈̈EMBACLOX DC; ¨̈̈̈̈KLOXERATE;¨̈̈̈̈OPTICLOX�Cloxacillin Sodium 7081-44-9; AMPICLOX*; ORBENINAntibiotic
NO Me
Cl
N
NOO
S
H COOH
Me
Me
H HH
Clozapine klö·za·pën8-Chloro-11-(4-methylpiperazin-1-yl)-5H-dibenzo[b,e][1,4]diazepine; C18H19ClN4;5786-21-0; CLOZARILAntipsychotic
NH
NN
NMe
Cl
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1-152�Co-amilofruse (BAN) see page 000�Co-amilozide (BAN) see page 000�Co-amoxiclav (BAN) see page 000Co-beneldopa (BAN) see page 000�Cocaine (BAN) kö·kän
(1R,2R,3S,5S)-2-Methyoxycarbonyltropan-3-yl benzoate; C17H21NO4;50-36-2�Cocaine Hydrochloride 53-21-4Local anaesthetic
NMe
COOMe
O
O
�Cocarboxylase (co-carboxylase) kö·kar·boks·i·läz3-(4-Amino-2-methylpyrimidin-5-ylmethyl)-5-{2-[dihydroxyphosphinyloxy-(hydroxy)phosphinyloxy]ethyl}-4-methyl-1,3-thiazolium hydroxide;diphosphothiamine; C12H20N4O8P2S; 154-87-0Co-enzyme
P
O
OH
O O P
O
OH
OH
N SN
N Me
NH2
Me
+
OH_
�Co-careldopa (BAN) see page 000�Co-codamol (BAN) see page 000�Co-codaprin (BAN) see page 000Co-cyprindiol (BAN) see page 000
�Cod-liver OilThe oil obtained from the fresh liver of the cod Gadus callarius L· and other speciesof Gadus refined and clarified by filtration at about 0°; MORHULIN*; NORATEX*;THOVALINE*Source of vitamins A and D
Codactide kö·dak·tïd[1-D-Serine,17,18-lysine]corticotrophin-(1-18)-octadecapeptide amideCorticotrophic peptide
D-Ser–Tyr–Ser–Met–Glu–His–Phe–Arg–
Trp–Gly–Lys–Pro–Val–Gly–Lys–Lys–
Lys–Lys–NH2�Co-danthramer (BAN) see page 000�Co-danthrusate (BAN) see page 000
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1-153
�Codeine (BAN) kö·dën7,8-Didehydro-4,5-epoxy-3-methoxy-9a-methylmorphinan-6-ol; C18H21NO3; 76-57-3�Codeine Hydrochloride 1422-07-7; ASPAV*�Codeine Phosphate 52-28-8 (anhydrous); 41444-62-6 (hemihydrate) GALCODINE;component in many proprietary preparationsAnalgesic
NMe
O
MeO
H
HO
�Co-dergocrine Mesilate kö-der·gö·krën me·si·lätEqual mass proportions of the methanesulfonates of (a) dihydroergocornine, (b)dihydroergocristine and (c) a- and b-dihydroergocryptine in the ratio 2:1;dihydroergotoxine mesilate; ergoloid mesilates (USAN); HYDERGINEUsed in treatment of impaired mental function in the elderly
�Co-dydramol (BAN) see page 000Co-fluampicil (BAN) see page 000Co-flumactone (BAN) see page 000�Colaspase (BAN)
L-Asparagine amidohydrolase obtained from selected strains of Escherichia coli, suchas ATCC 9637; asparaginase (USAN); 9015-68-3
�Colecalciferol (cholecalciferol) kö·lë·kal·si·fe·rol(5Z,7E)-(3S)-9,10-Secocholesta-5,7,10(19)-trien-3-ol; vitamin D3; C27H44O; 67-97-0; CACIT D3*; CALCEOS*; CALCICHEW D3*; ¨̈̈̈̈DUPHAFROLVitamin D analogue
HO
MeH
MeH
CH2
H
Me
Me
H
Colestipol kö·lest·i·polCo-polymer of diethylenetriamine and 1-chloro-2,3-epoxypropane;50925-79-6Colestipol Hydrochloride 37296-80-3; COLESTIDHypolipidaemic
�Colestyramine (cholestyramine) kö·lë·stï·ra·mënA styryl–divinylbenzene copolymer (about 2% divinylbenzene)containing quater-nary ammonium groups; 11041-12-6Colestyramine Chloride QUESTRANAnion exchange resin
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1-154Colfosceril Palmitate kol·fo·ser·ril parl·mi·tät
1,2-Dipalmitoyl-sn-glycero(3)phosphocholine; C40H80NO8P; 63-89-8; EXOSURFSurfactant replacement therapy
H3C[ CH2] 14CO C H
CH2OC[ CH2] 14CH3
O
CH2O P CH2CH2NMe3
O
O_
+
Colistimethate (colistin sulphomethate) ko·li·sti·me·thätAn antibiotic obtained from colistin sulphate by sulfomethylation with formalde-hyde and sodium bisulfite; 30387-39-4�Colistimethate Sodium 8068-28-8; COLOMYCIN INJECTIONAntibacterial
Colistin ko·lis·tinA mixture of antimicrobial peptides produced by a strain of Bacillus polymyxa var·colistinus; 1066-17-7�Colistin Sulphate 1264-7-8; COLOMYCINAntibacterial
Colistin Sulphomethate see ColistimethateCo-magaldrox (BAN) see page 000Co-methiamol (BAN) see page 000Co-phenotrope (BAN) see page 000�Copovidone (BAN) kö·po·vi·dön
A co-polymer of 1-vinylpyrrolidone and vinyl acetate in the massproportions 3:2Pharmaceutical aid
Copovithane (BAN) kö·po·vi·thänCopolymer of 2-methylenetrimethylene bis(methylcarbamate) and 1-vinyl-2-pyrrolidone in the approximate ratio of 1 part to 4 parts respectively;68045-74-9; BAY i 7433Tumour inhibitor
Copper Tetramibi Tetrafluoroborate (BAN)Tetrakis(2-methoxy-2-methylpropyl isocyanide-kN-copper(I) tetrafluoroborate;C24H44BCuF4N4O4Active ingredient in radiodiagnostic agent
Co-prenozide (BAN) see page 000�Co-proxamol (BAN) see page 000
Corticotropin (corticotrophin) kor·ti·kö·tro·pinThe peptide hormone from the anterior lobe of the pituitary which increases therate at which corticoid hormones are secreted by the adrenal gland; adrenocortico-trophin; ACTH; 9002-60-2; ACTHARAdrenocorticotrophic hormone
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1-155Cortisone kor·ti·sön
17a,21-Dihydroxypregn-4-ene-3,11,20-trione; C23H30O6; 53-06-5�Cortisone Acetate 50-04-4; CORTISYLCorticosteroid
Me
H
HMe
O
O
OHO
H
OH
Cortodoxone kor·tö·doks·ön17a,21-Dihydroxypregn-4-ene-3,20-dione; C21H30O4; 152-58-9Corticosteroid
Me
H
HMe
O
O
OH
H
OH
Co-simalcite (BAN) see page 000�Co-tenidone (BAN) see page 000Co-tetroxazine (BAN) see page 000�Co-triamterzide (BAN) see page 000Co-trifamole (BAN) see page 000�Co-trimazine (BAN) see page 000�Co-trimoxazole (BAN) see page 000Co-zidocapt (BAN) see page 000
Coumafos (coumaphos) kü·ma·fosO-3-Chloro-4-methylcoumarin-7-yl O,O-diethyl phosphorothioate; C14H16ClO5PS;56-72-4; ¨̈̈̈̈NEGASUNT*; ¨̈̈̈̈ PERIZINInsecticide
P
S
OEt
OOO
Me
Cl
OEt
�Coumetarol (cumetharol) kü·me·tha·rol4,4¢-Dihydroxy-3,3¢-(2-methoxyethylidene)dicoumarin; C21H16O7;4366-18-1Anticoagulant
O
OH
O
OH
O O
OMeH
Crisantaspase (BAN) kri·san·ta·späzL-Asparagine amidohydrolase obtained from cultures of Erwinia chrysanthemi (syn·E· carotovora); 9015-68-3; ̈ ERWINASE
Cytotoxic
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1-156Cromakalim krö·ma·ka·lim
(±)-trans-3-Hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)chroman-6-carbonitrile; C16H18N2O3; 94470-67-4; BRL 34915Antihypertensive
N
O
NC
MeMe
H
OH
OH
and enantiomer
Cromoglicic Acid (cromoglycic acid) krö·mö·glï·sik4,4¢-Dioxo-5,5¢-(2-hydroxytrimethylenedioxy)di(4H-chromene-2-carboxylic acid);C23H16O11; 16110-51-3�Sodium Cromoglicate cromolyn sodium (USAN); 15826-37-6; AEROCROM*;¨̈̈̈̈CROMOVET; INTAL; INTAL COMPOUND*; LOMUSOL; NALCROM; OPTICROM;RYNACROMProphylaxis of allergic conditions
O COOH
OOOO
HOOC O
H OH
Cropropamide krö·prö·pa·mïdN-[1-(Dimethylcarbamoyl)propyl]-N-propylcrotonamide; C13H24N2O2;633-47-6; ¨̈̈̈̈RESPIROT*Central nervous system stimulant
H3C N
CH3
CH3
NMe2O
HOH
H
and enantiomer
Croscarmellose kros·kar·me·lösA cross-linked, partly O-carboxymethylated cellulose�Croscarmellose SodiumPharmaceutical aid
�Crospovidone kros·po·vi·dönA cross-linked homopolymer of 1-vinyl-2-pyrrolidone; 9003-39-8Pharmaceutical aid
�Crotamiton krö·ta·mi·tonN-Ethylcrotono-o-toluidide; C13H17NO; 483-63-6; EURAXAnti-infective
N CH3
O H
HEtMe
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1-157Crotetamide (crotethamide) krö·te·ta·mïd
N-[1-(Dimethylcarbamoyl)propyl]-N-ethylcrotonamide; C12H22N2O2;6168-76-9; ¨̈̈̈̈RESPIROT*Central nervous system stimulant
H3C N
CH3
CH3
NMe2O
HOH
H
and enantiomer
Crotoxyfos (BAN) krö·toks·i·fos1-Phenylethyl-3-(dimethoxyphosphinyloxy)isocrotonate; C14H19O6P; 7700-17-6; FLY
REPELLENT
Insecticide
OMeP
O
OMe
OO
Me
H
OH Me
and enantiomer
Crufomate kroo·fö·mät4-tert-Butyl-2-chlorophenyl methyl methylphosphoramidate; C12H19ClNO3P; 299-86-5Insecticide; anthelmintic
OMeP
O
NHMe
O
Cl
Bu t
Cumetharol see Coumetarol
Cuproxoline kü·proks·o·lënCopper(II)bis(5,7-disulfo-8-quinolyl oxide)—diethylamine (1:4);C18H12CuN2O14S4; 13007-93-7; ̈̈̈̈̈ CUJECTreatment of copper deficiency
N
Cu OO
N SO3H
SO3HSO3H
HO3S4NHEt 2
Cyacetacide (cyacetazide) sï·a·se·ta·sïd2-Cyanoacetohydrazide; C3H5N3O; 140-87-4Anthelmintic
H2NN
ON
H
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1-158�Cyanocobalamin sï·a·nö·kö·ba·la·min
Coa-[(5,6-Dimethylbenzimidazolyl]-Cob-cyanocobamide; vitamin B12;C63H88CoN14O14P; 68-19-9; ¨̈̈̈̈ANIVIT B12; BC 500*; CYTACON; CYTAMEN;¨̈̈̈̈ FERROMAX; ¨̈̈̈̈ INTRAVIT 12; KETOVITE LIQUID*; ¨̈̈̈̈MULTIVET B12; OCTOVIT*;SOLIVITO N*; ¨̈̈̈̈VI-SORBIN*; ¨̈̈̈̈VITBEEVitamin B12 analogue
CN
H2N
OMe
H2N
O
H
Me
OO
HO
H
OHHHP
O
O_
ONH H Me
O O
HNH2
Me
Me
MeMe
O
H2N
Me
O
NH2 O
NH2
Me
N
N
Co
N
N
N
N Me
Me
H
H
H
H
+
Cyclamic Acid (BAN) sï·kla·mikN-Cyclohexylsulfamic acid; hexamic acid; C6H13NO3S; 100-88-9Sweetening agent
NHSO3H
�Cyclandelate sï·klan·de·lät3,3,5-Trimethylcyclohexyl mandelate; C17H24O3; 456-59-7Vasodilator
O
O
Me
Me
Me
OH
*
*
*
mixture of 8 stereoisomers
�CyclarbamateCyclopentane-1,1-diyldimethyl bis(phenylcarbamate); C21H24N2O4; 5779-54-4
OO NN
OO
H H
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1-159�Cyclizine sï·kli·zën
1-Benzhydryl-4-methylpiperazine; C18H22N2; 82-92-8�Cyclizine Hydrochloride 303-25-3; DICONAL*; FEMIGRAINE*; MIGRIL*; VALOIDCyclizine Lactate 5897-19-8; VALOIDCyclizine Tartrate CYCLIMORPH*Histamine H1-receptor antagonist
NNMe
Cyclobarbital (cyclobarbitone)sï·klö·bar·bi·tal5-(Cyclohex-1-enyl)-5-ethylbarbituric acid; C12H16N2O3; 52-31-3�Cyclobarbital Calcium 5897-20-1Hypnotic
N
NO
Et
OH
O
H
Cyclocoumarol sï·klö·kü·ma·rol3,4-Dihydro-2-methoxy-2-methyl-4-phenyl-2H-pyrano[3,2-c]chromen-5-one;C20H18O4; 518-20-7Anticoagulant
O
O
O
Me OMe
*
*
mixture of 4 stereoisomers
Cyclofenil sï·klö·fe·nil4,4¢-Cyclohexylidenemethanediyldi(phenyl acetate); C23H24O4; 2624-43-3Treatment of infertility
OAcAcO
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1-160Cycloguanil Embonate sï·klö·gwa·nil em·bo·nät
Bis(6-amino-1-p-chlorophenyl-1,2-dihydro-2,2-dimethyl-1,3,5-triazin-4-ylammonium) 3,3¢-dihydroxy-4,4¢-methylenedi-(2-naphthoate);(C11H15ClN5)2.C23H14O6; 609-78-9Antimalarial
MeMe
H3N
ClNH2
N
N
N CH2
COO_
OH
OH
COO_
2
+
Cyclomethycaine sï·klö·meth·ë·kän3-(2-Methylpiperidino)propyl 4-cyclohexyloxybenzoate; C22H33NO3;139-62-8Cyclomethycaine Sulphate 50978-10-4Local anaesthetic
O
O N
O Me
Cyclopentamine sï·klö·pen·ta·mën2-Cyclopentyl-1-methylethyl(methyl)amine; C9H19N; 102-45-4Cyclopentamine HydrochlorideSympathomimetic
CH3
H NHMe
and enantiomer
�Cyclopenthiazide sï·klö·pen·thï·a·zïd(RS)-6-Chloro-3-cyclopentylmethyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; C13H18ClN3O4S2; 742-20-1; NAVIDREX; NAVISPARE*;TRASIDREX*Diuretic
SNH
NH
OOS
H2N
OO
ClH
and enantiomer
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1-161Cyclopentolate sï·klö·pen·to·lät
2-Dimethylaminoethyl 2-(1-hydroxycyclopentyl)-2-phenylacetate; C17H25NO3; 512-15-2�Cyclopentolate Hydrochloride 5870-29-1; MINIMS CYCLOPENTOLATE;MYDRILATEAnticholinergic
O
NMe2O
HO
�Cyclophosphamide sï·klö·fos·fa·mïd2-Bis(2-chloroethyl)aminoperhydro-1,3,2-oxazaphosphorinane 2-oxide;C7H15Cl2N2O2P; 50-18-0 (anhydrous); 6055-19-2 (monohydrate); ENDOXANACytotoxic
NH
PO O
N
Cl
Cl
Cycloprolol see Cicloprolol�Cycloserine sï·klö·seer·rën
(R)-4-Amino-1,2-oxazolidin-3-one; C3H6N2O2; 68-41-7Antitubercular
NHO
OH2N
H
�Cyclosporin sï·klö·spor·rinCyclo[-[(R)-4-(E)-but-2-enyl-N,4-dimethyl-L-threonyl]-L-homoalanyl-(N-methylglycyl)-(N-methyl-L-leucyl)-L-valyl-(N-methyl-L-leucyl)-L-alanyl-D-alanyl-(N-methyl-L-leucyl)-(N-methyl-L-leucyl)-(N-methyl-L-valyl)-]; cyclosporinA; C62H111N11O12; 59865-13-3; ciclosporin (pINN); NEORAL; B12OPTIMMUNE;SANDIMMUNImmunosuppressant
Me
Ala_D_Ala_MeLeu_MeLeu_MeVal_N_C_CO_Abu_MeGly_MeLeu_Val_MeLeu
H
Me OHMeH
H
H
H
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1-162Cyclothiazide sï·klö·thï·a·zïd
6-Chloro-3,4-dihydro-3-(norborn-5-en-2-yl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; C14H16ClN3O4S2; 2259-96-3Diuretic
N
NHSH2 NO2 S
Cl
OO
H
mixture of stereoisomers
�Cycrimine1-Cyclopentyl-1-phenyl-3-piperidinopropan-1-ol; C19H29NO; 77-39-4
N
OH
and enantiomer
Cyfluthrin (BAN) sï·floo·thrin(RS)-a-Cyano-4-fluoro-3-phenoxybenzyl (1RS,3RS; 1RS,3SR)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; C22H18Cl2FNO3;68359-37-5; Bay Vl 1704Insecticide (veterinary)
H CN
O
O
Me
Me
H
Cl
Cl
H H
O
F
1S,3S-isomer
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2-1Cyhalothrin (BAN) sï·hä·lö·thrin
(RS)-a-Cyano-3-phenoxybenzyl *(Z)-(1RS,3RS)-3-(2-chloro-3,3,3-trifluoropropenyl)-2,2-dimethylcyclopropanecarboxylate; C23H19ClF3NO3; 68085-85-8; PP 563Insecticide*alternative designation: (1RS)-cis-3-(Z-2-chloro…
*
and enantiomer plus epimer at C*
H CN
O
O
Me
Me
H
Cl
F3C
H H
O
�Cypenamine2-Phenylcyclopentylamine; C11H15N; 15302-54-9
NH2
**
mixture of isomers
Cypermethrin (BAN) sï·per·më·thrin(RS)-a-Cyano-3-phenoxybenzyl *(1RS,3RS)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; C21H19Cl2NO3; 52315-07-8;BARRICADE; ¨̈̈̈̈CROVECT; ¨̈̈̈̈CYPOR; ¨̈̈̈̈DEOSECT; ¨̈̈̈̈EQUIVITE; ¨̈̈̈̈ FLECTRON;¨̈̈̈̈ PARASOL; ¨̈̈̈̈ROBUSTInsecticide*alternative designation: (1RS)-cis-3-(2,2 dichloro…
H CN
O
O
Me
Me
H
Cl
Cl
H H
O
and enantiomer plus epimer at C*
*
�Cyprenorphine(1) 2-[(-)-(5R,6R,7R,14R)-9a-Cyclopropylmethyl-4,5-epoxy-3-hydroxy-6-methoxy-6,14-ethenomorphinan-7-yl]propan-2-ol (2) (6R,7R,14R)-17-cyclopropylmethyl-7,8-dihydro-7-(1-hydroxy-1-methylethyl)-6-O-methyl-6,14-etheno-17-normorphine; C26H33NO4; 4406-22-8
N
O
HO
MeOHMe
HO Me
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2-2Cyproheptadine sï·prö·hep·ta·dën
5-(1-Methylpiperidin-4-ylidene)-5H-dibenzo[a,d]cycloheptene; C21H21N; 129-03-3�Cyproheptadine Hydrochloride 969-33-5; PERIACTINHistamine H1-receptor antagonist
N
Me
Cyproterone sï·prö·te·rön6-Chloro-1b,2b-dihydro-17a-hydroxy-3H-cyclopropa[1,2]pregna-4,6-diene-3,20-dione; C24H29ClO4; 2098-66-0�Cyproterone Acetate 427-51-0; ANDROCUR; CYPROSTAT; DIANETTE*Antiandrogen
Cl
O
CH3O
OH
H H
HMe
Me
Cyromazine sï·rö·ma·zënN-Cyclopropyl-1,3,5-triazine-2,4,6-triamine; C6H10N6; 66215-27-8; ¨̈̈̈̈VETRAZINInsecticide (veterinary)
N N
N N
NH2
H2NH
Cysteamine see Mercaptamine
�Cytarabine sï·ta·ra·bën1-b-D-Arabinofuranosylcytosine; C9H13N3O5; 147-94-4; CYTOSARCytotoxic
HO
N
NH2
OHO
OH
O
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2-3Cythioate (BAN) sï·thï·ö·ät
O,O-Dimethyl O-(4-sulfamoylphenyl) phosphorothioate; C8H12NO5PS2; 115-93-5Parasiticide
P
S
OMe
O
H2NO2S
OMe
�Dacarbazine da·kar·ba·zën5-(3,3-Dimethyltriazeno)imidazole-4-carboxamide; C6H10N6O; 4342-03-4; DTIC-DOMECytotoxic
N
N N
CONH2
N NMe2
H
Daclizumab da·kli·zü·mabImmunogloblin G1 (human-mouse monoclonal clone 1H4-gamma-chain anti-human interleukin 2 receptor), disulphide with human-mouse monoclonal clone1H4 light chain, dimer; 152923-56-3Immunosupressant; prophylaxis of acute organ rejection
Dactinomycin dak·ti·nö·mï·sinN2·1N2¢·1¢-(2-Amino-4,6-dimethyl-3-oxo-3H-phenoxazine-1,9-diyldicarbonyl)bis[threonyl-D-valylprolyl(N-methylglycyl)(N-methylvaline)-1.5-3.1-lactone]; actinomycin D; C62H86N12O16; 50-76-0; COSMEGEN LYOVACAntineoplastic
NO
Me
Me
O NH2
C
C
O
O
Thr–DVal–Pro–MeGly–MeVal
Thr–DVal–Pro–MeGly–MeVal
Dacuronium Bromide da·kûr·rö·në·um1,1¢-(3a-Acetoxy-17b-hydroxy-5a-androstan-2b,16b-diyl)bis(1-methylpiperidinium) dibromide; C33H58Br2N2O3; 27115-86-2Neuromuscular blocking agent
N
N
Me Me
OHMe
H
H
HMe
AcO
2Br+
+
_
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2-4Dalfopristin dal·fö·pris·tin
(5E,10E,12E,)-(3R,4R,14S,26R,26aS)-26-{[2-(Diethylamino)ethyl]sulfonyl}-8,9,14,15,24,25,26,26a-octahydro-14-hydroxy-3-isopropyl-4,12-dimethyl-3H-21,18-azeno-1H,22H-pyrrolo[2,1-c][1,8,4,19]dioxadiazacyclotetracosene-1,7,16,22(4H,17H)-tetrone; C34H50N4O9S; 112362-50-2Antibacterial
i Pr
O
NEt2
H
OS
O
HOH
H
H
HMe
O
NO
O
N
O
Me
N
O
H
Dalteparin Sodium dal·te·pa·rinSodium salt of depolymerised heparin obtained by nitrous acid degradation ofheparin from pork intestinal mucosa; the majority of the components have a 6-O-sulfo-2,5-anhydro-D-mannitol structure at the reducing end of their chain; themolecular weight of 90% of the components is between 2000 and 9000 and theaverage molecular weight is about 5000; the sulfur content is about 11%; FRAGMINAntithrombotic
�Danaparoid Sodium da·na·pa·roidA low-molecular-weight heparinoid consisting of a mixture of the sodium salts ofheparan sulfate (approximately 84%), dermatan sulfate (approximately 12%), andchondroitin-4-and 6-sulfates (approximately 4%); it is derived from pig intestinalmucosa; average molecular weight about 5500; 83513-48-8Anticoagulant
Danazol da·na·zol[1,2]Oxazolo[4¢,5¢:2,3]-17a-pregn-4-en-20-yn-17b-ol; C22H27NO2;17230-88-5; DANOLInhibitor of pituitary gonadotrophin secretion
NO
H
H
H
Me
Me OH
CH
Daniquidone da·ni·kwi·dön8-Aminoisoindolo[1,2-b]quinazolin-12(10H)-one; C15H11N3O;67199-66-0; BAY h 2049Cytotoxic
N
N
O
H2N
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2-5Danofloxacin da·nö·floks·a·sin
1-Cyclopropyl-6-fluoro-1,4-dihydro-7-{(1S,4S)-5-methyl-2,5-diazabicyclo[2.2.l]hept-2-yl}-4-oxoquinoline-3-carboxylic acid; C19H20FN3O3;112398-08-0Danofloxacin Mesilate 119478-55-6; CP-76,136-27Antibacterial (veterinary)
N
F COOH
O
N
MeN
Danthron see Dantron
Dantrolene dan·trö·lën1-(5-p-Nitrophenylfurfurylideneamino)hydantoin; C14H10N4O5;7261-97-4Dantrolene Sodium 14663-23-1; DANTRIUMMuscle relaxant
N
N
NO
O O
O2N
H
�Dantron (danthron) dan·tron1,8-Dihydroxyanthraquinone; C14H8O4; 117-10-2; AILAX*; CAPSUVAC*; CODALAX*;NORMAX*Laxative
O
O OHOH
�Dapsone dap·sönBis(4-aminophenyl) sulfone; C12H12N2O2S; 80-08-0; MALOPRIM*Antileprotic
O OS
H2N NH2
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2-6Daptomycin dap·tö·mï·sin
N-Decanoyl-L-tryptophyl-L-asparaginyl-L-aspartyl-L-threonylglycyl-L-ornithyl-L-aspartyl-D-alanyl-L-aspartylglycyl-D-seryl-threo-3-methyl-L-glutamyl-3-anthraniloyl-L-alanine 1.13-3.4-lactone; C72H101N17O26; 103060-53-3; Ly 146032Antibiotic
CH3[CH2]8CO_Trp_Asn_Asp_Thr_Gly_Orn_Asp_
D-Ala_Asp_Gly_D-Ser_threo(3_Me)Glu_Kyn
[Kyn = kynurenine = 3-anthraniloylalanine]
Darbepoetin Alfa dar·be·pö·e·tin al·fa[30-L-Asparagine, 32-L-threonine, 87-L-valine, 88-L-asparagine, 90-L-threonine]erythropoietin (human); C800H1300N228O255S5; 209810-58-2; NESPTreatment of anaemia
darbepoetin alfa has the following amino acid sequence:
APPRLICDSR VLERYLLEAK EAENITTGCN
ETCSLNENIT VPDTKVNFYA WKRMEVGQQA
VEVWQGLALL SEAVLRGQAL LVNSSQVNET
LQLHVDKAVS GLRSLTTLLR ALGAQKEAIS
PPDAASAAPL RTITADTFRK LFRVYSNFLR
GKLKLYTGEA CRTGD
Darifenacin da·ri·fe·na·sin(S)-2-{1-[2-(2,3-Dihydrobenzo[b]furan-5-yl)ethyl]pyrrolidin-3-yl}-2,2-diphenylacetamide; C28H30N2O2; 133099-04-4; UK-88,525Darifenacin Hydrobromide 133099-07-7; UK-88,525-04M3-Selective muscarinic receptor antagonist
N
H2NOC
O
H
Daunorubicin dor·nö·roo·bi·sinAn anthracycline antibiotic produced by Streptomyces peuceticus andS. coeruleorubidus; (1S,3S)-3-acetyl-1,2,3,4,6,11-hexahydro-3,5,12-trihydroxy-10-methoxy-6,11-dioxonaphthacen-1-yl 3-amino-2,3,6-trideoxy-a-L-lyxo-pyranoside;C27H29NO10; 20830-81-3�Daunorubicin Hydrochloride 23541-50-6; CEUBIDIN; DAUNOXOMECytotoxic
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2-7
O
OOMe
OH
OH
CH3
O
H
HO
O
NH2
HOMe
O
Dazmegrel daz·me·grel3-(3-Imidazol-l-ylmethyl-2-methylindol-l-yl)propionic acid; C16H17N3O2; 76894-77-4;UK-38485Thromboxane-synthetase inhibitor
N Me
N
N
COOH
Dazoxiben da·zoks·i·ben4-(2-Imidazol-l-ylethoxy)benzoic acid; C12H12N2O3; 78218-09-4;UK-37248Dazoxiben Hydrochloride 74226-22-5; UK-37248-01Thromboxane-synthetase inhibitor
COOH
ON
N
Deanol dë·a·nol2-Dimethylaminoethanol; C4H11NO; 3342-61-8Central nervous system stimulant
HONMe2
Debrisoquine de·brï·sö·kwën1,2,3,4-Tetrahydroisoquinoline-2-carboxamidine; C10H13N3; 1131-64-2�Debrisoquine Sulphate 581-88-4; DECLINAXAdrenergic neurone blocker
N NH2
NH
Debropol de·brö·pol(RS)-2-Bromo-2-nitropropan-l-ol; C3H6BrNO3; 24403-04-1; BTS 7706Antiseptic; preservative
H3C
Br NO2OH
and enantiomer
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2-8�Decamethonium Iodide (INNM)
N,N¢-Decamethylenebis(trimethylammonium) di-iodide; C16H38I2N2;541-22-0
Me3N[CH2] 10NMe3
+ +2I
_
Decitabine dë·sï·ta·bën4-Amino-1-(2-deoxy-b-D-erythro-pentofuranosyl)-1,3,5-triazin-2(1H)-one;C8H12N4O4; 2353-33-5; NSC 127716Cytotoxic
O
OH
HO
N
N
N
NH2
O
�Decoquinate de·kö·kwi·nätEthyl 6-decyloxy-7-ethoxy-4-hydroxyquinoline-3-carboxylate; C24H35NO5; 18507-89-6; ¨DECCOXAntiprotozoan
NEtO
CH3 [CH2 ]9 O
OH
COOEt
Deferiprone de·fe·ri·prön3-Hydroxy-1,2-dimethyl-4-pyridone; C7H9NO2; 30652-11-0; LlChelating agent
N
Me
Me
OH
O
Defibrotide dë·fi·brö·tïdPolydeoxyribonucleotides from bovine lung; the molecular weights range between45,000 and 55,000Antithrombotic; fibrinolytic
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2-9Deflazacort dë·flä·za·kort
11b-Hydroxy-2¢-methyl-3,20-dioxo[1,3]oxazolo[5¢,4¢:16,17]pregn-4-en-21-ylacetate; C25H31NO6; 14484-47-0; CALCORTCorticosteroid
O
Me
O
NMeHO
Me
O
OAc
�Dehydrocholic Acid dë·hï·drö·kö·lik3,7,12-Trioxo-5b-cholan-24-oic acid; C24H34O5; 81-23-2Laxative
O
Me
Me
Me
O
O
H H
H
COOH
H
H
Dehydroemetine dë·hï·drö·e·me·tën(S)-3-Ethyl-1,6,7,11b-tetrahydro-9,10-dimethoxy-2-[(R)-(1,2,3,4-tetrahydro-6,7-dimethoxy-1-isoquinolylmethyl)]-4H-benzo[a]quinolizine; 2,3-dehydroemetine;C29H38N2O4; 4914-30-1Antiprotozoan
N
H
Et
HN
MeO
MeO
H
OMe
OMe
Delmadinone del·ma·di·nön6-Chloro-17a-hydroxypregna-1,4,6-triene-3,20-dione; C21H25ClO3;15262-77-8Delmadinone Acetate 13698-49-2; ¨TARDAKProgestogen
O
Cl
O CH3
OHMe
Me
H H
H
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2-10Delprostenate del·pros·te·nät
(1) Methyl (2E,5Z)-7-{(1R,2R,3R,5S)-2-[(E)-(3R)-4-(3-chlorophenoxy)-3-hydroxybut-1-enyl]-3,5-dihydroxycyclopentyl}hepta-2,5-dienoate;(2) methyl (2E,5Z,13E)-(9S,11R,15R)-16-(3-chlorophenoxy)-9,11,15-trihydroxy-w-tetranorprosta-2,5,13-trienoate; C23H29ClO6;62524-99-6; ONO 1052Prostanoid luteolytic (veterinary)
O
H
H OHHHO
HO
Cl
COOMe
Deltamethrin (BAN) del·ta·më·thrin(S)-a-Cyano-3-phenoxybenzyl (1R,3S)-3-(2,2-dibromovinyl)-2,2-dimethylcyclopropanecarboxylate; C22H19Br2NO3; 52918-63-5Ectoparasiticide (veterinary)
O
H CN
O
O
Me
Me
H
Br
Br
H H
�Demecarium Bromide de·me·kä·rë·umN,N¢-Decamethylenebis(N,N,N-trimethyl-3-methylcarbamoyloxyanilinium)dibromide; C32H52Br2N4O4; 56-94-0Anticholinesterase
+NMe3
O N
O
Me
[ CH2] 10
+
_
NMe3
ON
O
Me
2Br
Dembrexine dem·breks·ëntrans-4-(3,5-Dibromo-2-hydroxybenzylamino)cyclohexanol; C13H17Br2NO2; 83200-09-3; ¨ SPUTOLOSINTreatment of respiratory diseases (veterinary)
HN
OH
Br
Br
H
OHH
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2-11Demeclocycline de·më·klö·sï·klën
(1) (4S,4aS,5aS,6S,12aS)-7-Chloro-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-1,11-dioxonaphthacene-2-carboxamide;(2) 7-chloro-6-demethyl-tetracycline; C21H21ClN2O8;127-33-3�Demeclocycline Hydrochloride 64-73-3; DETECLO*; LEDERMYCINAntibacterial
OH O HO O
CONH2
OH
NMe2HH
HHO
OH
Cl
Demecolcine de·më·kol·sën(RS)-6,7-Dihydro-1,2,3,10-tetramethoxy-7-methylamino-5H-benzo[a]heptalen-9-one; C21H25NO5; 477-30-5Antimitotic
MeO
MeO
MeO
NHMe
O
OMe
H
and enantiomer
Denatonium Benzoate de·na·tö·në·umBenzyldiethyl(2,6-xylylcarbamoylmethyl)ammonium benzoate; C28H34N2O3; 3734-33-6; BITREXAlcohol denaturant
NN
O EtEtMe
MeH
COO+_
Denbufylline den·bü·fi·lën1,3-Dibutyl-3,7-dihydro-7-acetonylpurine-2,6(1H)-dione; C16H24N4O3; 57076-71-8;BRL 30892Phosphodiesterase inhibitor
NBun
O
O
N
N
N
Bun
CH3
O
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2-12Deoxycortone see Desoxycortone
Depramine (balipramine) de·pra·mën5H-3-Dibenz[b,f]azepin-5-ylpropyldimethylamine; C19H22N2; 303-54-8; GP 31406Antiparkinsonian
N
NMe2
Deprodone de·prö·dön11b,17a-Dihydroxypregna-1,4-diene-3,20-dione; C21H28O4; 20423-99-8Deprodone Propionate 20424-00-4Corticosteroid
O
Me
H H
H
MeHO
CH3O
OH
Deptropine dep·trö·pën(1R,3r,5S)-3-(10,11-Dihydrodibenzo[a,d]cycloheptadien-5-yloxy)tropane;C23H27NO; 604-51-3�Deptropine Citrate 2169-75-7Anticholinergic; histamine H1-receptor antagonist
O
MeN
�Dequalinium Chloride de·kwa·li·në·umN,N-Decamethylenebis(4-amino-2-methylquinolinium chloride); C30H40Cl2N4; 522-51-0; DEQUACAINE*; DEQUADIN; LABOSEPTAnti-infective
N
MeH2N
N
Me NH2
CH2[ CH2] 8CH2+ +
2Cl_
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2-13Deserpidine dë·ser·pi·dën
Methyl 11-demethoxy-O-(3,4,5-trimethoxybenzoyl)reserpate; C32H38N2O8; 131-01-1Antipsychotic; antihypertensive
NN
OOC
H
H
H
CH3OOC
OMe
OMe
OMe
OMe
H
Desferrioxamine (BAN) dez·fe·rë·oks·a·mën30-Amino-3,14,25-trihydroxy-3,9,14,20,25-penta-azatriacontane-2,10,13,21,24-pentaone; deferoxamine (pINN); C25H48N6O8; 70-51-9�Desferrioxamine Mesilate 138-14-7; DESFERALChelating agent
H
NN
O
NOH
NNH3CO
O
O
OHH2N
O
HOH
Desipramine de·zi·pra·mën3-(10,11-Dihydro-5H-dibenz[b,f]azepin-5-yl)propyl(methyl)amine; C18H22N2; 50-47-5�Desipramine Hydrochloride 58-28-6; PERTOFRANAntidepressant
N
NHMe
Desirudin de·si·roo·din63-Desulfohirudin (hirudin isoform HV2); C287H440N80O110S6; 120993-53-5; CGP-39393; REVASC
Anticoagulant
VVYTDCTESG QNLCLCEGSN VCGQGNKCIL
GSDGEKNQCV TGEGTPKPQS HNDGDFEEIP
EEYLQ
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2-14�Deslanoside dez·lan·o·sïd
3b-[(O-b-D-Glucopyranosyl-(1® 4)-O-2,6-dideoxy-b-D-ribo-hexopyranosyl-(1® 4)-O-2,6-dideoxy-b-D-ribo-hexopyranosyl-(1® 4)-O-2,6-dideoxy-b-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-5b,12b-card-20(22)-enolide; deacetyl-lanatoside C; C47H74O19; 17598-6 5-1Cardiac glycoside
O
OHHO
OH
HO
Me
H
H
H
OH
MeOH
OO
O
O
OH
Me
O3
Desloratadine des·lor·ra·ta·dën8-Chloro-6,11-dihydro-11-(4-piperidylidene)-5H-benzo[5,6]cyclohepta[1,2-b]pyridine; C19H19ClN2; 100643-71-8; SCH 34117H1-receptor antagonist; treatment of allergic rhinitis
N
NH
Cl
�Deslorelin dez·lö·re·linC64H83N17O12; 57773-65-6Gonadorelin analogue
<Glu–His–Trp–Ser–Tyr–D-Trp–Leu–
Arg–Pro–NHEt
�Desmopressin des·mö·pres·sin[1-Deamino,8-D-arginine]vasopressin; C46H64N14O12S2; 16679-58-6; DDAVP;DESMOSPRAY; DESMOTABSAntidiuretic hormone
SCH2CH2CO_Tyr_Phe_Gln_Asn_Cys_Pro_
D-Arg_Gly_NH2
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2-15�Desogestrel de·zö·jes·trel
13b-Ethyl-11-methylene-18,19-dinor-17a-pregn-4-en-20-yn-17b-ol; C22H30O;54024-22-5; MARVELON*; MERCILON*Progestogen
H
H
H
Et OH
CHH
H2C
Desomorphine de·zö·mor·fën(1) (-)-(5S)-4,5-Epoxy-9a-methylmorphinan-3-ol; (2) 6-deoxy-7,8-dihydromorphine; C17H21NO2; 427-00-9Opioid analgesic
NMe
O
HO
H
�Desonide de·zö·nïd11b,21-Dihydroxy-16a,17a-isopropylidenedioxypregna-1,4-diene-3,20-dione;C24H32O6; 638-94-8
O
H
H
H
MeHO
O CH2OH
O
OMe
Me
Me
Desoximetasone (desoxymethasone) de·zoks·ë·me·ta·sön9a-Fluoro-11b,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione; C22H29FO4;382-67-2; STIEDEXCorticosteroid
O
Me
HO
F H
H
Me
Me
OOH
H
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2-16Desoxycortone (deoxycortone) dëz·oks·ë·kor·tön
21-Hydroxypregn-4-ene-3,20-dione; (rINN); C21H30O2; 64-85-7Desoxycortone Acetate desoxycorticosterone acetate (USAN); 56-47-3;Desoxycortone Pivalate 808-48-0Corticosteroid
Me
H
HMe
O
O
H
OH
Desoxymethasone see Desoximetasone
Detomidine de·to·mi·dën4-(2,3-Dimethylbenzyl)imidazole; C12H14N2; 76631-46-4Detomidine Hydrochloride 90038-01-0; ¨DOMOSEDANTranquilliser (veterinary)
N
NH
Me
Me
�Dexamethasone deks·a·me·tha·sön9a-Fluoro-11b,17a,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione;C22H29FO5; 50-02-2; ¨AZIUM; ¨DEXAMYCIN*; ¨DEXAZONE; MAXIDREX*;MAXITROL*; ¨OPTICORTEN; ORADEXON; OTOMIZE*; SOFRADEX*; ¨̈̈̈̈ SOLUDEX�Dexamethasone Acetate 55812-90-3; ¨DUPHACORT*Dexamethasone Isonicotinate 2265-67-7; ¨VOREN; DEXA-RHINASPRAY*Dexamethasone Phenylpropionate 1879-72-7; ¨DEXAFORT*Dexamethasone Phosphate 312-93-6; DECADRONDexamethasone Pivalate 1926-94-9; ¨OPTICORTENOL-S*�Dexamethasone Sodium Phosphate 2392-39-4; ¨COLVSONE; DECADRON;¨DEXADRESON; ¨DEXAFORT*; ¨DUPHACORT Q; DUPHA-DUOCORT*; ORADEXON;¨OXYCOMPLEX*Corticosteroid
O
Me
HO
F H
H
Me
Me
OOH
OH
Dexamfetamine (dexamphetamine) deks·am·fe·ta·mën(S)-a-Methylphenethylamine; (+)-amphetamine; dextroamphetamine (USAN);C9H13N; 51-64-9�Dexamfetamine Sulphate 51-63-8; DEXEDRINECentral nervous system stimulant
NH2
MeH
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2-17Dexbrompheniramine deks·brom·fen·ï·ra·mën
(R)-3-(4-Bromophenyl)-3-(2-pyridyl)propyldimethylamine; C16H19BrN2; 132-21-8Dexbrompheniramine Maleate 2391-03-9Histamine H1-receptor antagonist
N
NMe2
Br
H
Dexchlorpheniramine deks·klor·fen·î·ra·mën(S)-[3-(4-Chlorophenyl)-3-(2-pyridyl)propyl]dimethylamine; C16H19ClN2; 25523-97-1Histamine H1-receptor antagonist
N
NMe2H
Cl
Dexetimide deks·e·ti·mïd(S)-2-(1-Benzyl-4-piperidyl)-2-phenylglutarimide; C23H26N2O2;21888-98-2Anticholinergic
O
O
NH
N
Dexfenfluramine deks·fen·flûr·ra·mën(S)-N-Ethyl-a-methyl-3-trifluoromethylphenethylamine; C12H16F3N;3239-44-9; ADIFAXAppetite suppressant
CH3
H NHMe
F3C
Dexibuprofen deks·ï·bü·prö·fen(S)-2-(4-Isobutylphenyl)propionic acid; C13H18O2; 51146-56-6Analgesic; anti-inflammatory
Bui
COOH
MeH
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2-18Dexketoprofen deks·kë·tö·prö·fen
(S)-2-(3-Benzoylphenyl)propionic acid; C16H14O3; 22161-81-5Dexketoprofen Trometamol KERAL
Analgesic
O
COOH
H Me
Dexmedetomidine deks·me·de·to·mi·dën(S)-4-[1-(2,3-Xylyl)ethyl]imidazole; C13H16N2; 113775-47-6; MPV-1440Alpha2-adrenoceptor antagonist
HN
NH Me Me
Me
Dexpanthenol deks·pan·the·nol(R)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide; C9H19NO4; 81-13-0; CONCAVIT*Analogue of pantothenic acid
HON OH
Me Me
H OH
O
H
Dexpropranolol deks·prö·pra·no·lol(R)-1-Isopropylamino-3-(1-naphthyloxy)propan-2-ol; C16H21NO2;5051-22-9Antiarrhythmic
O NHPr iOHH
Dexrazoxane deks·ra·zoks·än(S)-4,4¢-Propylenedi(piperazine-2,6-dione); C11H16N4O4; 24584-09-6;ICRF-187Dexrazoxane HydrochloridePrevention of anthracycline-induced cardiotoxicity
HN
NN
NH
MeH
O
OO
O
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2-19Dextran deks·tran
Polyanhydroglucose produced by the action of Leuconostoc mesenteroides on sucroseand subsequent controlled hydrolysis and fractionation of the high molecularweight dextran thus formed, or the same substance obtained by any other means.The weight-average molecular weight is referred to by a specifying number: egdextran 40, 45, 70, 110, 150. The number multiplied by 1000 corresponds to theapproximate weight-average molecular weight, eg dextran 40 has a weight-averagemolecular weight of about 40,000;9004-54-0; DEXTRAVEN; GENTRAN; LOMODEX; MACRODEX; RHEOMACRODEX;TEARS NATURALE*Plasma volume expander
Dextranomer deks·tra·no·merDextran cross-linked with 1-chloro-2,3-epoxypropane; 56087-11-7; DEBRISANPromoter of wound healing
OH OH OH
HO
OH
HCOH
CH2
O
HO OOH OH
OO
O
OHOHO
O
CH2
O
OOH OH
OO
OOH
O
OOH
HO
OH
n
Dextriferron deks·tri·fe·ronA colloidal solution of iron(III) hydroxide in complex with partially hydrolyseddextrin; 8063-26-1Treatment of iron-deficiency anaemia
�Dextrin (BAN) deks·trinMaize or potato starch partially hydrolysed by heat with or without the aid ofsuitable acids or buffers; 9004-53-9Pharmaceutical aid
Dextromethorphan deks·trö·me·thor·fan(1) (+)-3-Methoxy-9a-methylmorphinan; (2) (9S,13S,14S)-6,18-dideoxy-7,8-dihydro-3-O-methylmorphine; C18H25NO; 125-71-3; FRANOLYN SED; TUSANA*�Dextromethorphan Hydrobromide 6700-34-1 (monohydrate);125-69-9 (anhydrous); CONTAC COUGHCAPS; component of many other proprietarypreparationsAntitussive
H
MeO
NMe
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2-20Dextromoramide deks·trö·mo·ra·mïd
(S)-1-(3-Methyl-4-morpholino-2,2-diphenylbutyryl)pyrrolidine; C25H32N2O2; 357-56-2�Dextromoramide Tartrate 2922-44-3; PALFIUMOpioid analgesic
NN
OO H Me
Dextropropoxyphene deks·trö·prö·poks·ë·fën(1S,2R)-1-Benzyl-3-dimethylamino-2-methyl-1-phenylpropyl propionate;C22H29NO2; 469-62-5�Dextropropoxyphene Hydrochloride propoxyphene hydrochloride (USAN);1639-60-7; COSALGESIC*; DISTALGESIC*�Dextropropoxyphene Napsilate 26570-10-5; DOLOXENEOpioid analgesic
NMe2
OCH3
O
Ph
MeH
Dextrorphan deks·tror·fan(+)-9a-Methylmorphinan-3-ol; C17H23NO; 125-73-5Opioid antitussive
H
HO
NMe
Dextrothyroxine deks·trö·thï·roks·ën4-O-(4-Hydroxy-3,5-di-iodophenyl)-3,5-di-iodo-D-tyrosine; C15H10I4NO4; 137-53-1Dextrothyroxine Sodium 7054-08-2 (hydrate); 137-53-1 (anhydrous)Treatment of hypercholesterolaemia
O
I
I
I
HO COOH
H NH2
I
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2-21Diacetamate dï·a·se·ta·mät
4-Acetamidophenyl acetate; C10H11NO3; 2623-33-8Analgesic
OAc
AcHN
Diacetolol dï·a·se·to·lol3¢-Acetyl-4¢-(2-hydroxy-3-isopropylaminopropoxy)acetanilide; C16H24N2O4; 28197-69-5Diacetolol Hydrochloride 69796-04-9; M&B 16942ABeta-adrenoceptor antagonist
AcHN
O NHPri
CH3
O
H OH
and enantiomer
Diacetylnalorphine (BAN) dï·a·së·tïl·na·lor·fën(1) (-)-(5R,6S)-9a-Allyl-4,5-epoxymorphin-7-en-3,6-diyl diacetate;(2) 3,6-di-O-acetyl-17-allyl-17-normorphine; C23H27NO5; 2748-74-5Opioid analgesic
N
O
AcO
H
AcO
CH2
Diamocaine dï·a·mö·kän2-[1-(2-Anilinoethyl)-4-phenyl-4-piperidyloxy]ethyldiethylamine; C25H37N3O;27112-37-4Local anaesthetic
NN
O
NEt2H
Diamorphine (BAN) dï·a·mor·fën4,5-Epoxy-17-methylmorphinan-3,6-diyl diacetate; C21H23NO5; 561-27-3�Diamorphine Hydrochloride 1502-95-0; DIAGESILOpioid analgesic
NMe
O
AcO
H
AcO
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2-22�Diamfenetide (diamphenethide) dï·am·fe·ne·tïd
b,b¢-Oxydi(aceto-p-phenetidide); C20H24N2O5; 36141-82-9; ̈ CORIBANAnthelmintic
OO
O
NHAcAcHN
Diampromide dï·am·prö·mïdN-[2-(N-Methylphenethylamino)propyl]propionanilide; C21H28N2O;552-25-0Analgesic
NN
H Me
Me
CH3O
and enantiomer
�Diamthazole (BAN) dï·am·tha·zôl2-(2-Dimethylamino-1,3-benzothiazol-5-yloxy)ethyldiethylamine; dimazole(pINN); C15H23N3OS; 95-27-2Antifungal
S
NNMe2
OEt2N
Diatrizoic Acid see Amidotrizoic Acid
�Diaveridine dï·a·ve·ri·dën5-Veratrylpyrimidine-2,4-diyldiamine; C13H16N4O2; 5355-16-8; ¨ SAQUADIL*Antiprotozoan
N
N
OMe
OMeNH2H2N
�Diazepam dï·ä·ze·pam7-Chloro-1,3-dihydro-1-methyl-5-phenyl-1,4-benzodiazepin-2-one; C16H13ClN2O;439-14-5; ATENSINE; DIAZEMULS; STESOLID; TENSIUM; VALCLAIR; VALIUMHypnotic; anxiolytic
N
NCl
OMe
Diazinon see Dimpylate
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2-23�Diazoxide dï·a·zoks·ïd
7-Chloro-3-methyl-2H-1,2,4-benzothiadiazine 1,1-dioxide; C8H7ClN2O2S; 364-98-7; EUDEMINETreatment of hypotension and endogenous hyperinsulinism
Me
O OCl
N
SNH
Dibekacin dï·be·ka·sin6-O-(3-Amino-3-deoxy-a-D-glucopyranosyl)-2-deoxy-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-a-D-erythro-hexopyranosyl)-D-streptamine; 3¢,4¢-dideoxykanamycin B;C18H37N5O8; 34493-98-6Dibekacin Sulphate 58580-55-5Antibacterial
O
O
NH2
NH2
HO
OH2NCH2
NH2
O
OH
HOCH2
HOH2N
�Dibenzepin dï·ben·ze·pin10-(2-Dimethylaminoethyl)-5,10-dihydro-5-methyldibenzo[b,e][1,4]diazepin-11-one; C18H21N3O; 4498-32-2Antidepressant
N
N
O
Me
Me2N
Dibrompropamidine (dibromopropamidine) dï·brom·prö·pa·mi·dën3,3¢-Dibromo-4,4¢-trimethylenedioxydibenzamidine; C17H18Br2N4O2; 496-00-4�Dibrompropamidine Isetionate 614-87-9; BROLENE OINTMENT; GOLDEN EYEOINTMENT; ̈ OTORYL*Anti-infective
O
Br
NH
NH2H2N
NH
Br
O
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2-24�Dibupyrone
Sodium 2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl-(isobutyl)-aminomethanesulfonate; C16H22N3NaO4S; 1046-17-9
NSNaO
Bu iO O O
N
NMe Me
�Dichlofenthion (BAN) dï·klö·fen·thï·onO-2,4-Dichlorophenyl O,O-diethyl phosphorothioate; C10H13Cl2O3PS;97-17-6; V-C 13Insecticide
P
S
OEt
O
Cl
Cl
OEt
�Dichloralphenazone (BAN) dï·klor·ral·fen·a·zönA 2:1 complex of chloral hydrate and phenazone; C4H6Cl6O4.C11H13N2O; 480-30-8Hypnotic
ClOH
OH
ClCl
N NMe
Me
O
2
�Dichlorophen dï·klor·rö·fen2,2¢-Methylenebis(4-chlorophenol); C13H10Cl2O2; 97-23-4; ¨̈̈̈̈CANOVELTAPEWORMER; ¨̈̈̈̈CATOVEL TAPEWORMER; ¨̈̈̈̈COMPANION; ¨̈̈̈̈EASY TAPE; ¨̈̈̈̈RUBYAnthelmintic
OH
Cl
OH
Cl
Dichlorophenarsine dï·klor·rö·fe·nar·sën3-Amino-4-hydroxyphenyldichloroarsine; C6H6AsCl2NO; 455-83-4Antifungal
AsCl2
NH2
HO
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2-25Dichloroxylenol dï·klor·rö·zï·le·nol
2,4-Dichloro-3,5-xylenol; C8H8Cl2O; 133-53-9Antiseptic
OH
Cl
Me
Cl
Me
Dichlorphenamide see Diclofenamide
Dichlorvos dï·klor·vos2,2-Dichlorovinyl dimethyl phosphate; C4H7Cl2O4P; 62-73-7; ¨̈̈̈̈AQUAGARD;¨ATGARD; ¨NUVAN STAYKIL*; ¨NUVAN TOP*; ¨TASK; ¨VAPONAAnthelmintic; insecticide
P
O
OMe
OCl
Cl
OMe
Dichromium Trioxide (BAN) dï·krö·më·um trï·oks·ïdChromium(III) sesquioxide; Cr2O3; 1308-38-9Diagnostic aid
Diclazuril dï·klaz·ûr·ril(±)-4-Chlorophenyl[2,6-dichloro-4-(2,3,4,5-tetrahydro-3,5-dioxo-1,2,4-triazin-2-yl)phenyl]acetonitrile; C17H9Cl3N4O2; 101831-37-2; ¨̈̈̈̈CLINACOXCoccidiostat
N
N
NH
H CN Cl
ClCl
O
O
and enantiomer
Diclofenac dï·klö·fe·nak[2-(2,6-Dichloroanilino)phenyl]acetic acid; C14H11Cl2NO2; 15307-86-5; VOLTAROL�Diclofenac Diethylamine VOLTAROL EMULGELDiclofenac Potassium 15307-81-0; CATAFLAM�Diclofenac Sodium 15307-79-6; DICOLFLEX; DICLOMAX; DICLOTARD;DICLOZIP; DIGENAC; FLAMRASE; ISCLOFEN; LOFENSAID; MOTIFENE;RHUMALGAN; RUMAFEN; SLOFENAC; VOLRAMAN; VOLSAID; VOLTAROLAnalgesic; anti-inflammatory
N
Cl
Cl COOHH
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2-26�Diclofenamide (dichlorphenamide) dï·klö·fe·na·mïd
4,5-Dichlorobenzene-1,3-disulfonamide; C6H6Cl2N2O4S2; 120-97-8Carbonic anhydrase inhibitor
SO2NH2
Cl
Cl
H2NO2S
Dicloxacillin dï·kloks·a·si·lin(6R)-6-[3-(2,6-Dichlorophenyl)-5-methyl-1,2-oxazole-4-carboxamido]penicillanicacid; C19H17Cl2N3O5S; 3116-76-5; BRL-1702; R-13423�Dicloxacillin Sodium 13412-64-1 (monohydrate); 343-55-5 (anhydrous)Antibacterial
NO Me
Cl
N
NOO
S
H COOH
Me
Me
H H
Cl
H
�Dicobalt EdetateCobalt [ethylenediaminetetra-acetato(4-)-N,N¢,O,O¢]cobalt(II); C10H12Co2N2O8;36499-65-7Cyanide antidote
O
Co
N
OO
OOO
O
N
O_
__
_
2+Co 2+
Dicyclomine see Dicycloverine
Dicycloverine (dicyclomine) dï·sï·klö·ver·rën2-Diethylaminoethyl bicyclohexyl-1-carboxylate; C19H35NO2; 77-19-0�Dicycloverine Hydrochloride 67-92-5; DIARREST*; KOLANTICON*;MERBENTYLAnticholinergic
ONEt2
O
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2-27Didanosine dï·da·nö·sën
2¢,3¢-Dideoxy-1,9-dihydro-9-b-D-ribofuranosyl-6H-purine-6-one;2¢,3¢-dideoxyinosine; DDI; C10H12N4O3; VIDEXAntiviral
O
HO
N
NN
HN
O
�DieldrinProduct containing 85 per cent of (1R,4S,4aS,5S,6S,7R,8R,8aR)-1,2,3,4,10,10-hexachloro-6,7-epoxy-1,4,4a,5,6,7,8,8a-octahydro-1,4:5,8-dimethanonaphthalene; C12H8Cl6O; 60-57-1
85%
ClO
Cl
Cl
Cl
ClH
H
H
H
Cl
�Dienestrol (dienoestrol) dï·ën·ë·strol4,4¢-{Bis[(E)-ethylidene]ethylene}diphenol; C18H18O2; 84-17-3Oestrogen
HO
OHH Me
Me H
�Diethadione5,5-Diethyl-1,3-oxazinane-2,4-dione; C8H13NO3; 702-54-5
NH
O O
Et
EtO
Diethazine dï·eth·a·zën2-(Phenothiazin-10-yl)ethyldiethylamine; C18H22N2S; 60-91-3Anticholinergic
S
NNEt2
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2-28Diethylcarbamazine dï·ë·thïl·kar·ba·ma·zën
N,N-Diethyl-4-methylpiperazine-1-carboxamide; C10H21N3O; 90-89-1�Diethylcarbamazine Citrate 1642-54-2Anthelmintic
N
N
Me
CONEt2
Diethylpropion dï·ë·thïl·prö·pë·ona-Diethylaminopropiophenone; amfepramone (pINN); C13H19NO;90-84-6�Diethylpropion Hydrochloride 134-80-5; APISTATE*; TENUATE DOSPANAppetite suppressant
NEt2
O
H Me
and enantiomer
Diethylstilbestrol (stilboestrol) dï·ëthïl·stil·bë·strol(E)-4,4´-(1,2-Diethylvinylene)diphenol; C18H20O2;56-53-1; TAMPOVAGAN
Oestrogen
Et
Et
HO
OH
Diethylthiambutene dï·ë·thïl·thï·am·bú·tënDiethyl[3,3-di-(2-thienyl)-1-methylprop-2-enyl]amine; C16H21NS2;86-14-6Diethylthiambutene HydrochlorideOpioid analgesic
S
S
NH2
MeH
and enantiomer
Diethyltoluamide dï·ë·thïl·tol·ü·a·mïdN,N-Diethyl-m-toluamide; C12H17NO; 134-62-3; AUTANInsect repellent
CONEt2Me
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2-29Difenidol (diphenidol) dï·fe·ni·dol
1,1-Diphenyl-4-piperidinobutan-1-ol; C21H27NO; 972-02-1Antiemetic
N
OH
Difenoxin dï·fen·oks·in1-(3-Cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylic acid;C28H28N2O2; 28782-42-5Antidiarrhoeal
NCN COOH
Difetarsone dï·fe·tar·sönN,N¢-Ethylenebis(4-aminophenylarsonic acid); C14H18As2N2O6;3639-19-18Antiprotozoan
NN
As
As
OH
OH
O
O
OH
OH H
H
Diflorasone dï·flo·ra·sön6a,9a-Difluoro-11b,17a,21-trihydroxy-16b-methylpregna-1,4-diene-3,20-dione;C22H28F2O5; 2557-49-5Diflorasone Diacetate 33564-31-7; U-34865Corticosteroid
O
Me
HO
F H
H
Me
Me
OOH
H
F
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2-30Diflucortolone dï·floo·kor·to·lön
6a,9a-Difluoro-11b,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione;C22H28F2O4; 2607-06-9�Diflucortolone Valerate 59198-70-8; NERISONECorticosteroid
O
Me
HO
F H
H
Me
Me
OOH
H
F
Diflumidone dï·floo·mi·dön3¢-Benzoyldifluoromethanesulfonanilide; C14H11F2NO3S; 22736-85-2Anti-inflammatory
N
O
CHF2S
OO
H
�Diflunisal dï·floo·ni·sal5-(2,4-Difluorophenyl)salicylic acid; C13H8F2O3; 22494-42-4; DOLOBIDAnalgesic; anti-inflammatory
COOH
OHF
F
�Digitoxin di·ji·toks·in3b-[(O-2,6-Dideoxy-b-D-ribo-hexopyranosyl-(1® 4)-O-2,6-dideoxy-b-D-ribo-hexopyranosyl-(1® 4)-2,6-dideoxy-b-D-ribo-hexopyranosyl)oxy]-14b-hydroxy-5b-card-20(22)-enolide; C41H64O13; 71-63-6; ¨CARDIO-TABSCardiac glycoside
Me
H
H
H
OH
Me
OO
O
O
OH
Me
OH3
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2-31�Digoxin di·joks·in
3b-[O-2,6-dideoxy-b-D-ribo-hexopyranosyl-(1® 4)-O-2,6-dideoxy-b-D-ribo-hexopyranosyl-(1® 4)-2,6-dideoxy-b-D-ribo-hexopyranosyl)oxy]-12b,14b-dihydroxy-5b-card-20(22)-enolide; C41H64O14; 20830-75-5; LANOXINCardiac glycoside
Me
H
H
H
OH
MeOH
OO
O
O
OH
Me
OH3
Dihydralazine dï·hï·dra·la·zënPhthalazine-1,4-diyldihydrazine; C8H10N6; 484-23-1�Dihydralazine Sulphate 7327-87-9Vasodilator
NH
NH
NNH2
NNH2
Dihydrocodeine dï·hï·drö·kö·dën4,5-Epoxy-3-methoxy-17-methylmorphinan-6-ol; C18H23NO3; 125-28-0�Dihydrocodeine Tartrate 5965-13-9; DF 118; DHC-COTINUS; GALAKE*;PARAMOL*; REMEDEINE*Opioid analgesic
NMe
O
MeO
H
HO
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2-32Dihydroergocristine dï·hï·drö·er·gö·kris·tën
(1) (2´R,5´S)-5´-benzyl-9,10-dihydro-12´-hydroxy-2´-isopropyl-18-oxoergotaman-3´,6´-dione;(2) (6aR,9R,10aR)-N-[(2R,5S,10aS,10bS)-5-benzyl-10b-hydroxy-2-isopropyl-3,6-dioxooctahydro-8H-[1,3]oxazolo[3,2-a]pyrrolo[2,1-c]pyrazin-2-yl]-7-methyl-4,6,6a,7,8,9,10,10a-octahydroindolo[4,3-fg]quinoline-9-carboxamide;C35H34N5O5; 17479-19-5Dihydroergocristine Mesilate 24730-10-7Used in treatment of impaired mental function in the elderly
N
N
O
HN
NMe
NH
H
H
HO
Pri
O
OH
H
OH
Dihydroergotamine dï·hï·drö·er·go·ta·mën(5¢S,8R)-5¢-Benzyl-9,10-dihydro-12¢-hydroxy-2¢-methyl-3¢,6¢,18-trioxoergotaman;C33H37N5O5; 511-12-6�Dihydroergotamine Mesilate 6190-39-2�Dihydroergotamine Tartrate 5989-77-5Vasoconstrictor
NO
NOO
OH
H
H
Me
NH
OH
HN
NH
Me
H
Dihydrostreptomycin dï·hï·drö·strep·tö·mï·sinO-2-Deoxy-2-methylamino-a-L-glucopyranosyl-(1® 2)-O-5-deoxy-3-C-hydroxymethyl-a-L-lyxofuranosyl-(1® 4)-N 1,N 3-diamidino-D-streptamine;C21H41N7O12; 128-46-1�Dihydrostreptomycin Sulphate 5490-27-7; ¨̈̈̈̈DEVOMYCIN-D*Antibiotic (veterinary)
O
H3C
OH
OOH
HOOH
NH
H2N NH
NH
NH2HN
O
O NHMe
OHHO
OH
CH2OH
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2-33Dihydrotachysterol dï·hï·drö·ta·kis·ste·rol
(5Z,7E)-(3S,10S)-9,10-Secoergosta-5,7,22-trien-3-ol; C28H46O; 67-96-9; A.T.10Vitamin D analogue
Me
Me
H
HO
H
HMe
MeH H Me
Me
Di-iodohydroxyquinoline dï·ï·ö·dö·hï·droks·ë·kwi·no·lën5,7-Di-iodoquinolin-8-ol; iodoquinol (USAN); C9H5I2NO; 83-73-8Antiprotozoan
N
OH
I
I
Dilevalol dï·le·va·lol5-{(R)-1-Hydroxy-2-[(R)-1-methyl-3-phenylpropylamino]ethyl}salicylamide;C19H24N2O3; 75659-07-3; R,R-labetalolDilevalol Hydrochloride 75659-08-4; Sch 19927Beta-adrenoceptor antagonist
N
MeH
OHHCONH2
OH
H
Diloxanide dï·loks·a·nïd2,2-Dichloro-4¢-hydroxy-N-methylacetanilide; C9H9Cl2NO2; 579-38-4�Diloxanide Furoate 3736-81-0; FURAMIDEAntiprotozoan
HO
NCl
Me
O
Cl
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2-34Diltiazem dil·tï·a·zem
(2S,3S)-5-(2-Dimethylaminoethyl)-2,3,4,5-tetrahydro-2-(4-methoxyphenyl)-4-oxo-1,5-benzothiazepin-3-yl acetate; C22H26N2O4S; 42399-41-7�Diltiazem Hydrochloride 33286-22-5; ADIZEM; ANGIOZEM; ANGITIL;BRITIAZEM; CALAZEM; CALCICARD; DILZEM; SLOZEM; TAZILDIL; TILDIEM;ZEMTARDCalcium antagonist
S
N
H
OMe
OMe2N
OAc
H
�Dimefline dï·mef·lën8-Dimethylaminomethyl-7-methoxy-3-methyl-2-phenylchromen-4-one; C20H21NO3;1165-48-6Central nervous system stimulant
O
O
Me
MeO
NMe2
�Dimenhydrinate dï·men·hï·dri·nät2-Benzhydryloxyethyldimethylammonium 8-chloro-1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-ide; C17H21NO.C7H7ClN4O2;523-87-5; DRAMAMINE;Histamine H1-receptor antagonist
ONMe2
N
N
N
NCl
O
O
Me
MeH
,
Dimenoxadole dï·men·oks·a·dôl2-Dimethylaminoethyl 2-ethoxy-2,2-diphenylacetate; C20H25NO3;509-78-4Opioid analgesic
ONMe2
O
EtO
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2-35Dimepheptanol dï·me·fep·ta·nol
6-Dimethylamino-4,4-diphenylheptan-3-ol; C21H29NO; 545-90-4Opioid analgesic
NMe2H
CH3
HOH3C
H
mixture of isomers
Dimepregnen dï·me·preg·nen3b-Hydroxy-6a,16a-dimethylpregn-4-en-20-one; C23H36O2; 21208-26-4Antioestrogen
HO
Me
Me
Me
Me
CH3O
H
H
H
Dimepropion dï·me·prö·pë·ona-Dimethylaminopropiophenone; metamfepramone (pINN); C11H15NO; 15351-09-4Appetite suppressant
CH3
O
NMe2H
and enantiomer
�Dimercaprol dï·mer·ka·prol2,3-Dimercaptopropan-1-ol; BAL·; C3H8OS2; 59-52-9Chelating agent
HO SHH SH
and enantiomer
Dimesone dï·me·sön9a-Fluoro-11b,21-dihydroxy-16a,17a-dimethylpregna-1,4-diene-3,20-dione;C23H31FO4; 25092-07-3Anti-inflammatory
O
Me
Me
Me
O
F
H
H
HOOH
Me
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2-36Dimethisoquin see Quinisocaine
Dimethisterone dï·me·thi·ste·rön17b-Hydroxy-6a,21-dimethyl-17a-pregn-4-en-20-yn-3-one; C17H24N2O;79-64-1;Progestogen
O
Me
Me
H
H
H
Me
OH
CH3
Dimethothiazine see Dimetotiazine
Dimethoxanate dï·me·thoks·a·nät2-(2-Dimethylaminoethoxy)ethyl phenothiazine-10-carboxylate; C19H22N2O3S; 477-93-0Antitussive
S
N OO
NMe2
O
�Dimethyl Sulfoxide dï·më·thïl sul·foks·ïdDimethyl sulfoxide; DMSO; C2H6OS; 67-68-5; HERPID*; IDURIDIN*;RIMSO-50; VIRUDOX*Pharmaceutical aid
SH3C CH3
O
Dimethylthiambutene dï·më·thïl·thï·am·bú·tënDimethyl[3,3-di-(2-thienyl)-1-methylprop-2-enyl]amine; C14H17NS2;524-84-5Opioid analgesic
SSNMe2
H Me
and enantiomer
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2-37Dimethyltubocurarine dï·më·thïl·tü·bö·kûr·rar·rën
Dimethyl ether of (+)-tubocurarine; C39H46N2O6; 33335-58-9Neuromuscular blocker
ONMe
O
Me2N
CH2
MeO
OMe
OMe
Me
H
H+
(cation)
�Dimeticone (dimethicone) dï·me·ti·könPoly(dimethylsiloxane); each dimeticone name is followed by a number referring tothe viscosity of the substance: eg dimeticone 20 (viscosity of 17·0 to 23·0centistokes) dimeticone 200 (viscosity of 190 to 210 centistokes) 9006-65-9; ¨̈̈̈̈BIRP;component in many proprietary preparationsAntifoaming agent; water repellent
Si
Me
Me
MeSi
Me
Me
Me O
n
�Dimetindene (dimethindene) dï·me·tin·dënDimethyl(2-{3-[1-(2-pyridyl)ethyl]-1H-inden-2-yl}ethyl)amine; C20H24N2; 5636-83-9Histamine H1-receptor antagonist
N
NMe2
CH3H
and enantiomer
�Dimetotiazine (dimethothiazine)N,N-Dimethyl-10-(2-dimethylaminopropyl)phenothiazine-2-sulfonamide; fonazinemesylate (USAN); C19H25N3O2S2; 7456-24-8
and enantiomer
O OS
NMe2
H Me
Me2N
S
N
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2-38�Dimetridazole dï·me·tri·da·zôl
1,2-Dimethyl-5-nitroimidazole; C5H7N3O2; 551-92-8; ̈ EMTRYL; ¨̈̈̈̈HARKANKER-SOLUBLEAntiprotozoan
N
NNO2
Me Me
Diminazene dï·mi·na·zën1,3-Bis(4-amidinophenyl)triazene; C14H15N7; 536-71-0Diminazene Aceturate 908-53-4; ¨BERENILAntiprotozoan
NN
N
NH2H2N
NHNH
H
Dimpylate (diazinon) dim·pi·lätO,O-Diethyl O-(2-isopropyl-6-methylpyrimidin-4-yl) phosphorothioate;C12H21N2O3PS; 333-41-5; ¨̈̈̈̈ALL SEASONS; ¨̈̈̈̈CANOVEL (collars); ¨̈̈̈̈CATOVEL(collars); ¨̈̈̈̈DERASECT; ¨DIAZADIP; ¨̈̈̈̈DROPLIX; ¨̈̈̈̈GOLD FLEECE; ¨̈̈̈̈NEOCIDOL;¨̈̈̈̈ PARACIDE PLUS; ¨̈̈̈̈ PREVENDER; ¨̈̈̈̈ PREVENTEF; ¨̈̈̈̈ SUMMER FLYInsecticide
P
S
OEt
O
N
N
Me
Pr i OEt
�Dinitolmide dï·nï·tol·mïd3,5-Dinitro-o-toluamide; C8H7N3O5; 148-01-6; ¨ SALCOSTATCoccidiostat
CONH2
Me
NO2O2N
Dinoprost dï·nö·prost(1) (Z)-7-{1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-(3S)-3-hydroxyoct-1-enyl]cyclopentyl}hept-5-enoic acid; (2) (5Z,13E)-(9S,11R,15S)-9,11,15-trihydroxyprosta-5,13-dienoic acid; prostaglandin F2a; C20H34O5; 537-11-1�Dinoprost Trometamol 38562-01-5; PROSTIN F2; ¨LUTALYSEInducer of uterine muscle contraction
CH3
H
H OHHHO
HO
COOH
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2-39�Dinoprostone dï·nö·pros·tön
(1) (Z)-7-{(1R,2R,3R)-3-Hydroxy-2-[(E)-(3S)-3-hydroxyoct-1-enyl]-5-oxocyclopentyl}hept-5-enoic acid; (2) (5Z,13E)-11R,15S-dihydroxy-9-oxoprosta-5,13-dienoic acid; prostaglandin E2; C20H32O5; 363-24-6; PREPIDIL; PROPESS;PROSTIN E2Inducer of uterine muscle contraction
CH3
H
H OHHHO
COOH
O
Dioxamate dï·oks·a·mät2-Methyl-2-nonyl-1,3-dioxolan-4-ylmethyl carbamate; C15H29NO4;3567-40-6Antiarkinsonian
O
O
OH2N
O
Me
CH3
**
mixture of 4 isomers
Dioxaphetyl Butyrate dï·oks·a·fë·tïl bú·ti·rätEthyl 4-morpholino-2,2-diphenylbutyrate; C22H27NO3; 467-86-7Opioid analgesic
N
OCOOEt
Dioxation (dioxathion) dï·oks·a·tï·onA mixture consisting essentially of cis-and trans-S,S¢-1,4-dioxan-2,3-diyl bis(O,O-diethyl phosphorodithioate); 78-34-2; C12H26O6P2S4Insecticide; acaricide
P
S
OEt
S OEt
P
S
OEt
S OEtO
O
*
*
mixture of 4 stereoisomers
Dipenine Bromide see Diponium Bromide
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2-40Diperodon dï·pe·rö·don
3-Piperidinopropylene bis(phenylcarbamate); C22H27N3O4; 101-08-6Local anaesthetic
HN O
O N
ON
H
O
H
and enantiomer
Diphemanil Metilsulfate dï·fe·ma·nil4-Benzhydrylidene-1,1-dimethylpiperidinium methylsulfate; C21H27NO4S; 62-97-5Anticholinergic
NMe2
CH3SO4
+
_
Diphenadione dï·fe·na·dï·ön2-Diphenylacetylindan-1,3-dione; C23H16O3; 82-66-6Anticoagulant
O O
O
Diphenhydramine dï·fen·hï·dra·mën2-Benzhydryloxyethyldimethylamine; C17H21NO; 58-73-1�Diphenhydramine Hydrochloride 147-24-0; BENYLIN*; CALADRYL*;GUANOR*; HISTALIX*; MEDINEX; NORADRAN*; NYTOL; PROPAIN*; UNIFLU*Histamine H1-receptor antagonist
ONMe2
Diphenidol see Difenidol
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2-41Diphenoxylate dï·fe·noks·i·lät
Ethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate;C30H32N2O2; 915-30-0�Diphenoxylate Hydrochloride 3810-80-8; LOMOTIL*; REASEC*; TROPERGEN*Antidiarrhoeal
NCN COOEt
Diphenylpyraline dï·fë·nïl·pi·ra·lën4-Benzhydryloxy-1-methylpiperidine; C19H23NO; 147-20-6�Diphenylpyraline Hydrochloride 132-18-3; ESKORNADE*Histamine H1-receptor antagonist
O
NMe
Dipipanone dï·pi·pa·nön4,4-Diphenyl-6-piperidinoheptan-3-one; C24H31NO; 467-83-4�Dipipanone Hydrochloride 856-87-1; DICONAL*Opioid analgesic
and enantiomer
CH3O
MeH
N
Dipivefrine dï·pi·ve·frën(RS)-4-[1-Hydroxy-2-(methylamino)ethyl]-o-phenylene dipivalate; dipivefrin;C19H29NO5; 52365-63-6Dipivefrine Hydrochloride 64019-93-8; PROPINESympathomimetic
and enantiomer
NHMeH OH
Me3CCOO
Me3CCOO
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2-42Diponium Bromide (dipenine bromide) dï·pö·në·um brö·mïd
2-(Dicyclopentylacetoxy)ethyltriethylammonium bromide; C20H38BrNO2; 2001-81-2Anticholinergic
ONEt3
O
Br_+
Diprenorphine dï·pre·nor·fën(1) 2-[(-)-(5R,6R,7R,14S)-9a-Cyclopropylmethyl-4,5-epoxy-3-hydroxy-6-methoxy-6,14-ethanomorphinan-7-yl]propan-2-ol; (2) (6R,7R,14S)-17-cyclopropylmethyl-7,8-dihydro-7-(1-hydroxy-1-methylethyl)-6-O-methyl-6,14-ethano-17-normorphine; C26H35NO4; 14357-78-9�Diprenorphine Hydrochloride 16808-86-9; ¨REVIVONAntagonist to opioid analgesics
N
O
HO
MeOH
OHMe Me
Diprobutine dï·prö·bú·tën1,1-Dipropylbutylamine; C10H23N; 61822-36-4Antiparkinsonian
CH3 CH2 CH2
CH3 CH2 CH2 C
CH3 CH2 CH2
NH2
�Diprophylline dï·prö·fi·lën7-(2,3-Dihydroxypropyl)theophylline; C10H14N4O4; 479-18-5; ¨THEOCARDINBronchodilator
NMe
Me
O
O
N
N
N
H OHOH
and enantiomer
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2-43Diproteverine dï·prö·te·ver·rën
1-(3,4-Diethoxybenzyl)-3,4-dihydro-6,7-di-isopropoxyisoquinoline; C26H35NO4;69373-95-1; BRL 40015Diproteverine Hydrochloride 69373-88-2; BRL 40015AAnti-anginal
N
OEt
OPr i
Pr i O
OEt
�Dipyridamole dï·pi·ri·da·môl2,2¢,2¢¢,2¢¢¢-{[4,8-Dipiperidinopyrimido[5,4-d]pyrimidine-2,6-diyl]dinitrilo}tetraethanol; C24H40N8O4; 58-32-2; MODAPLATE; PERSANTINVasodilator
N
N
N
N
N
N
N
OH
N
HO
OH
HO
Dipyrone (BAN) dï·pï·rönSodium (2,3-dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)(methyl)amino-methanesulfonate; noramidopyrine methanesulfonate sodium (pINN);methampyrone; metamizole sodium; C13H16N3NaO4S; 68-89-3; ¨BUSCOPANCOMPOSITUM*; ¨ ISAVERIN*Analgesic
NN
N SO3NaO
Me
Me
Me
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2-44�Dirithromycin di·ri·thrö·mï·cin
(1R,2R,3R,6R,7S,8S,9R,10R,12R,13S,15R,17S)-7-(2,6-Dideoxy-3-C,3-O-dimethyl-a-L-ribo-hexopyranosyloxy)-3-ethyl-2,10-dihydroxy-15-(2-methoxyethoxymethyl)-2,6,8,10,12,17-hexamethyl-9-(3,4,6-trideoxy-3-dimethylamino-b-L-xylo-hexopyranosyloxy)-4,16-dioxa-14-azabicyclo[11.3.1]heptadecan-5-one; C42H78N2O14; 62013-04-1; LY237216Antibacterial
OMeO
HN
O
O
Me
OMe
Me
HO
O
O
OH
Me
NMe2
O
Me
Me
MeOH
OHOMe
Et
O
MeH
Disodium Edetate see EdeticAcid
�Disofenin dï·sö·fe·nin(2,6-Di-isopropylphenylcarbamoylmethylimino)di(acetic acid); C18H26N2O5; 65717-97-7Diagnostic aid
NN
OCOOH
COOH
Pr i
Pr iH
�Disopyramide dï·sö·pi·ra·mïd4-Di-isopropylamino-2-phenyl-2-(2-pyridyl)butyramide; C21H29N3O;3737-09-5; RYTHMODAN�Disopyramide Phosphate 22059-60-5; DIRYTHMINAntiarrhythmic
N
NPr i2
CONH2
and enantiomer
�Dispersible Cellulose (BAN)Microcrystalline cellulose containing about 10% of carmellose sodium; AVICEL RCPharmaceutical aid
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2-45Distigmine Bromide dï·stig·mën
3,3¢-[N,N¢-Hexamethylenebis(methylcarbamoyloxy)]bis(1-methylpyridiniumbromide); C22H32Br2N4O4; 15876-67-2; UBRETIDAnticholinesterase
+ +N
O N
Me
O
Me
[CH2]6 N O
N
Me
O
Me
2Br_
Disulfamide (disulphamide) dï·sul·fa·mïd5-Chlorotoluene-2,4-disulfonamide; C7H9ClN2O4S; 671-88-5Diuretic
Cl
SO2NH2H2NO2S
Me
�Disulfiram dï·sul·fi·ramTetraethylthiuram disulfide; C10H20N2S4; 97-77-8; ANTABUSETreatment of alcoholism
Et2N SS NEt2
S
S
Disulphamide see Disulfamide
Dithiazanine dï·thï·a·za·nën3-Ethyl-2-[5-(3-ethyl-1,3-benzothiazol-2-ylidene)penta-1,3-dienyl]-1,3-benzothiazolium (cation); C23H23N2S2; 514-73-8Anthelmintic
N
S
N
S
Et Et +
(cation)
�Dithranol di·thra·nol1,8-Dihydroxyanthrone; dioxyanthranol; anthralin (USAN); C14H10O3;1143-38-0; 480-22-8; ALPHODITH; ANTRANOL*; ANTRADERM; DITHROCREAM;DITHROLAN*; MICANOL; PSORADATE*; PSORIN*Dithranol Triacetate 16203-97-7Treatment of psoriasis
OH O OH
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2-46Ditophal dï·tö·fal
S,S¢-Diethyl dithioisophthalate; C12H14O2S2; 584-69-0Antileprotic
EtS SEt
O O
Dobutamine dö·bú·ta·mën(±)-4-[2-(3-p-Hydroxyphenyl-1-methylpropylamino)ethyl]pyrocatechol;C18H23NO3; 34368-04-2Dobutamine Hydrochloride 49745-95-1; DOBUTREX; POSIJECTCardiac stimulant
N
H Me
OH
HO
OH
H
and enantiomer
Docetaxel dö·së·taks·eltert-Butyl {(1S,2R)-2-[(2S,5R,7S,10R,13S)-4-acetoxy-2-benzoyloxy-1,7,10-trihydroxy-9-oxo-5,20-epoxytax-11-en-13-yloxycarbonyl]-2-hydroxy-1-phenylethyl}carbamate; C43H53NO14; 114977-28-5; TAXOTERE
Antineoplastic
HHN
O OMe
Me
Me
OHHO
Me
Me
PhO
O OAcO
H OH
OMe
O
MeO
OH
�Docusate Sodium do·kü·sät sö·dë·umSodium 1,4-bis(2-ethylhexyl) sulfosuccinate; dioctyl sodium sulfosuccinate;C20H37NaO7S; 577-11-7; CAPSUVAC*; DIOCTYL; FLETCHER’S ENEMETTE;MOLCER; NORGALAX; NORMAX*; WAXSOLLaxative
O
O
SO3Na
O
OH3C
H3CHEt
EtH
*
*
mixture of stereoisomers
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2-47Dodicin (BAN) dö·di·sin
3,6,9-Triazahenicosanoic acid; C18H39N3O2; 6843-97-6Surface active agent
H
H
HN
NN COOHH3C [CH2]11
Dofamium Chloride dö·fä·më·um2-(N-Dodecanoyl-N-methylamino)ethyldimethyl(phenylcarbamoylmethyl)-ammonium chloride; C25H44ClN3O2; 54063-35-3Anti-infective
NN
N
O
Me
CH2
O
CH3H 10
Cl+_
Me Me
Dofetilide dö·fe·ti·lïd4¢-(2-{Methyl[4-(methylsulfonylamino)phenethyl]amino}ethoxy)methane-sulfonanilide; C19H27N3O5S2; 115256-11-6; UK-68798Antiarrhythmic
O O
Me
O OS
NH
ON
Me
HN Me
S
Dolasetron do·la·së·tron(6R,8r,9aS)-3-Oxoperhydro-2H-2,6-methanoquinolizin-8-yl indole-3-carboxylate;C19H20N2O3; 115956-12-2Dolasetron Mesilate 115956-13-3 (monohydrate); MDL73,147EFSerotonin 5HT3-receptor antagonist
H
O
N
O
H
H
O
HH
N
�Domiphen Bromide dö·mi·fenDodecyldimethyl-2-phenoxyethylammonium bromide; C22H40BrNO;538-71-6; BRADOSOLAnti-infective
ONMe2
[CH2]11CH3
Br_+
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2-48�Domperidone dom·pe·ri·dön
5-Chloro-1-{1-[3-(2,3-dihydro-2-oxobenzimidazol-1-yl)propyl]-4-piperidyl}-1,3-dihydrobenzimidazol-2-one; C22H24ClN5O2; 57808-66-9; MOTILIUM�Domperidone Maleate MOTILIUM TABLETSAntiemetic
H
N
NO
Cl
O
N
N
N
H
Donepezil dö·ne·pe·zil(RS)-2-[(1-Benzyl-4-piperidyl)methyl]-5,6-dimethoxyindan-1-one; C24H29NO3;142057-79-2Donepezil Hydrochloride 142057-77-0; ARICEPT
Acetylcholinesterase inhibitor; treatment of dementia
N
O
MeO
MeO
H
and enantiomer
Donetidine do·ne·ti·dën5-(1,2-Dihydro-2-oxo-4-pyridylmethyl)-2-{2-[5-(dimethylaminomethyl)-furfurylthio]ethylamino}pyrimidin-4(1H)-one; C20H25N5O3S;99248-32-5; SK&F 93574Histamine H2-receptor antagonist
HO
HN
N
N NS
CH2NMe2
O
OH
Dopamine dö·pa·mën4-(2-Aminoethyl)pyrocatechol; C8H11NO2; 51-61-6�Dopamine Hydrochloride 62-31-7Sympathomimetic
NH2HO
HO
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2-49Dopexamine dö·peks·a·mën
4-{2-[6-(Phenethylamino)hexylamino]ethyl}pyrocatechol; C22H32N2O2; 86197-47-9Dopexamine Hydrochloride 86484-91-5; DOPACARDCardiac stimulant
NCH2NHO
HO
H H6
Doramectin dor·ra·mek·tin(l0E,14E,16E)-(lR,4S,5¢S,6S,6¢R,8R,12S,13S,20R,21R,24S)-6¢-Cyclohexyl-5¢,6¢-dihydro-21,24-dihydroxy-5¢,11,13,22-tetramethyl-2-oxo-3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentacosa-10,14,16,22-tetraene-6-spiro-2¢(2H-pyran)-12-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside; C50H74O14; 117704-25-3;¨̈̈̈̈DECTOMAXAntiparasitic (veterinary)
O
O
OOO
OO
O O
HO
Me
OH
H
OMe
MeH
HMe
H
OH
OMe
MeH
Me
Me
Dornase Alfa dor·näs al·faRecombinant human deoxyribonuclease I, derived from cloned human pancreaticDNase I and having the same amino acid sequence and glycosylation pattern ashuman deoxyribonuclease I. It is capable of enzymatic digestion of high molecularweight, leukocyte-derived, extracellular DNA; C1321H1995N339O396S9; 143831-71-4;PULMOZYMEEnzyme (reduction of mucus viscosity)
For labelling purposes, the following three letter code, to indicate the method ofproduction, is approved:
(rch) produced from genetically engineered Chinese hamster ovary cells.
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2-50
LKIAAFNIQT FGETKMSNAT LVSYIVQILS
RYDIALVQEV RDSHLTAVGK LLDNLNQDAP
DTYHYVVSEP LGRNSYKERY LFVYRPDQVS
AVDSYYYDDG CEPCGNDTFN REPAIVRFFS
RFTEVREFAI VPLHAAPGDA VAEIDALYDV
YLDVQEKWGL EDVMLMGDFN AGCSYVRPSQ
WSSIRLWTSP TFQWLIPDSA DTTATPTHCA
YDRIVVAGML LRGAVVPDSA LPFNFQAAYG
LSDQLAQAIS DHYPVEVMLK
Dorzolamide dor·zol·a·mïd(4S,6S)-4-Ethylamino-5,6-dihydro-6-methyl-4H-thieno[2,3-b]thiopyran-2-sulfonamide 7,7-dioxide; C10H16N2O4S3; 120279-96-1Dorzolamide Hydrochloride 130693-82-2; TRUSOPTCarbonic anhydrase inhibitor; treatment of glaucoma and ocular hypertension
O OS SMe
NHEt
SO2NH2
Dosulepin (dothiepin) dö·sü·le·pin(E)-3-(Dibenzo[b,e]thiepin-11-ylidene)propyldimethylamine; C19H21NS; 113-53-1�Dosulepin Hydrochloride 897-15-4 (monohydrate); PROTHIADENAntidepressant
S
HMe2HN
Dothiepin see Dosulepin
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2-51Doxacurium Chloride doks·a·kur¢·rë·um
A mixture of the (1R,1¢S,2S,2¢R), (1R,1¢R,2S,2¢S) and (1S,1¢S,2R,2¢R)stereoisomers (a meso isomer and two enantiomers respectively) of 1,1¢,2,2¢,3,3¢,4,4¢-octahydro-6,6¢,7,7¢,8,8¢-hexamethoxy-2,2¢-dimethyl-1,1¢-bis(3,4,5-trimethoxybenzyl)-2,2¢-[butanedioylbis(oxytrimethylene)]di-isoquinoliniumdichloride, each isomer being in a trans configuration at the 1 and 2 positions of theisoquinolinium rings; C56H78Cl2N2O16; 83348-52-1 (total racemate); 106819-53-8(meso-isomer); BW A938USkeletal muscle relaxant
2Cl
N
CH2
O
MeO
OMe
OMe
OMe
OMe
OMe
Me+ +
_
mixture of stereoisomers
CH2CH2
MeN
CH2
O
OMe
OMe
MeO
OMe
MeO
MeO
O O
Doxapram doks·a·pram(RS)-1-Ethyl-4-(2-morpholinoethyl)-3,3-diphenyl-2-pyrrolidone; C24H30N2O2; 309-29-5�Doxapram Hydrochloride 7081-53-0; 113-07-5 (anhydrous); DOPRAMCentral nervous system stimulant
NO
Et
N
O
H
and enantiomer
Doxazosin doks·ä·zö·sin2-[4-(2,3-Dihydro-1,4-benzodioxin-2-ylcarbonyl)piperazin-l-yl]-6,7-dimethoxyquinazolin-4-ylamine; C23H25N5O5; 74191-85-8Doxazosin Mesilate 77883-43-3; CARDURAVasodilator
N
N
N
N
O
O
O
NH2
MeO
MeO
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2-52Doxepin doks·ë·pin
(E)-3-(Dibenz[b,e]oxepin-11-ylidene)propyldimethylamine; C19H21NO;1668-19-5�Doxepin Hydrochloride 1229-29-4; SINEQUANAntidepressant
O
NMe2
Doxibetasol (doxybetasol) doks·ë·bë·ta·sol9a-Fluoro-11b,17a-dihydroxy-16b-methylpregna-1,4-diene-3,20-dione;C22H29FO4; 1879-77-2Corticosteroid
O
Me
F
MeHO
MeOH
CH3O
H
H
Doxorubicin doks·ö·roo·bi·sinAn anthracycline antibiotic produced by Streptomyces coeruleorubidus or S. peucetiusvar. coesius; (8S,10S)-10-[(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyl)oxy]-8-hydroxyacetyl-6,8,11-trihydroxy-1-methoxy-7,8,9,10-tetrahydronaphthacene-5,12-dione; 3-hydroxyacetyldaunorubicin; C27H29NO11; 23214-92-8�Doxorubicin Hydrochloride 25316-40-9; CAELYXCytotoxic
O
OOMe
OH
OH
O
OH
H
HO
O
NH2
HOMe
O
Doxybetasol see Doxibetasol
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2-53Doxycycline doks·ë·sï·klën
(1) (4S,4aR,5S,5aR,6R,12aS)-4-Dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide; (2)6-deoxy-5b-hydroxytetracycline; C22H24N2O8;564-25-0�Doxycycline Hyclate Doxycycline hydrochloride hemiethanolate hemihydrate;24390-14-5; ¨̈̈̈̈ORNICURE; ¨RONAXAN; VIBRAMYCINAntibacterial
OH O HO O
CONH2
OH
NMe2HH
OH
Me OH
Doxycycline Fosfatex (BAN) doks·ë·sï·klën fos·fa·teks6-Deoxy-5b-hydroxytetracycline¾ metaphosphoric acid¾ sodium metaphosphate inthe ratio 3:3:1; (C22H24N2O8)3·NaPO3·(HPO3)3;83038-87-3; AB08Antibacterial
Doxylamine doks·ïl·a·mënDimethyl-2-[a-methyl-a-(2-pyridyl)benzyloxy]ethylamine; C17H22N2O;469-21-6Doxylamine Succinate 562-10-7; SYNDOL*, VICKS MEDINITEHistamine H1-receptor antagonist
N
ONMe2
Me
and enantiomer
Draflazine dra·fla·zën(+)-1-(4-Amino-2,6-dichlorocarbaniloylmethyl)-4-[5,5-bis(4-fluoro-phenyl)pentyl]piperazine-2-carboxamide; C30H33Cl2F2N5O2;120770-34-5; R75231Antianginal
N
N
CONH2
NO
Cl
Cl
NH2
FF
H
![Page 232: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/232.jpg)
2-54Droperidol drö·pe·ri·dol
1-{1-[3-(4-Fluorobenzoyl)propyl]-1,2,3,6-tetrahydro-4-pyridyl}benzimidazolin-2-one; C22H22FN3O2; 548-73-2; DROLEPTANAntipsychotic
H
N
N
F
O
ON
Dropropizine drö·prö·pi·zën3-(4-Phenylpiperazin-1-yl)propane-1,2-diol; C13H20N2O2; 17692-31-8Antitussive
N
N OHH OH
and enantiomer
Drostanolone drö·sta·no·lön17b-Hydroxy-2a-methyl-5a-androstan-3-one; dromostanolone; C20H32O2; 58-19-5Drostanolone Propionate 521-12-0Anabolic steroid; androgen
O
Me
H
Me
H H
MeOCOEt
H
H
Drotebanol drö·te·ba·nol3,4-Dimethoxy-9a-methylmorphinan-6,14-diol; C19H27NO4; 3176-03-2Opioid analgesic; antitussive
NMe
MeO
OH
HO
MeO
![Page 233: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/233.jpg)
2-55�Droxypropine
1-{1-[2-(2-Hydroxyethoxy)ethyl]-4-phenyl-4-piperidyl}propan-1-one; C18H27NO3;15599-26-5
NO
OH
H3C
O
Dutasteride dü·ta·ste·rïd3-Oxo-2¢,5¢-bis(trifluoromethyl)-4-aza-5a-androst-1-ene-17b-carboxanilide;C27H30F6N2O2; 164656-23-9; GI 198745XTestosterone reductase inhibitor
NH
OH
H H
HMe
MeNO
CF3
CF3
H
H
Dyclonine (dyclocaine) dï·klö·nën4¢-Butoxy-3-piperidinopropiophenone; C18H27NO2; 586-60-7Dyclonine Hydrochloride 536-43-6Local anaesthetic
OH3C
N
O
�Dydrogesterone dï·drö·jes·te·rön9b,10a-Pregna-4,6-diene-3,20-dione; C21H28O2; 152-62-5; DUPHASTON;FEMAPAK*; FEMOSTON*Progestogen
O
Me
H H
H
MeCH3O
H
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2-56Dyflos (BAN) dï·flos
Di-isopropyl phosphorofluoridate; C6H14FO3P; 55-91-4Anticholinesterase
Me O
Me
P
FMe
O Me
O
Ebastine e·ba·stën4¢-tert-Butyl-4-[4-(benzhydryloxy)piperidino]butyrophenone; C32H39NO2; 90729-43-4; LAS-W-090Histamine H1-receptor antagonist
But
O
N
O
Ecogramostim e·kö·gra·mos·timRecombinant methionyl human granulocyte macrophage colony-stimulating factor;123120-99-0Immunosuppressantecogramostim has the following amino acid sequence:
MAPARSPSPS TQPWEHVNAI QEARRLLNLS
RDTAAEMNET VEVISEMFDL QEPTCLQTRL
ELYKQGLRGS LTKLKGPLTM IASHYKQHCP
PTPETSCATQ IITFESFKEN LKDFLLVIPF
DCWEPVQE
Econazole ë·ko·na·zôl1-[2,4-Dichloro-b-(p-chlorobenzyloxy)phenethyl]imidazole; C18H15Cl3N2O; 27220-47-9�Econazole Nitrate 68797-31-9; ECONACORT*; ECOSTATIN;GYNO-PEVARYL; PEVARYL; PEVARYL TC*Antifungal
O
N
NCl
ClCl
H
and enantiomer
![Page 235: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/235.jpg)
2-57Ecothiopate Iodide e·kö·thï·ö·pät
(2-Diethoxyphosphinylthioethyl)trimethylammonium iodide; C9H23INO3PS; 513-10-0; PHOSPHOLINE IODIDEAnticholinesterase
P
O
OEt
SMe3N
OEt I_+
Ectylurea ek·tïl·ûr·rë·a(2-Ethylcrotonoyl)urea; C7H12N2O2; 95-04-5Hypnotic; anxiolytic
H N NH2
Et
CH3 O O
H
Edetic Acid e·dë·tikEthylenediaminetetra-acetic acid; C10H16N2O8; 60-00-4�Disodium Edetate 139-33-3; URIFLEX*; URO-TAINER*Chelating agent
N N
COOHHOOC
COOHHOOC
Edogestrone e·dö·jes·trön3,3-Ethylenedioxy-6-methyl-20-oxopregn-5-en-17a-yl acetate; C26H38O5; 809-01-8Progestogen
O
O
Me H
Me
H H
Me
CH3O
OAc
�Edrophonium Chloride e·drö·fö·në·umEthyl(3-hydroxyphenyl)dimethylammonium chloride; C10H16ClNO;116-38-1; ¨̈̈̈̈CAMSILONAnticholinesterase
NMe2
Et
HO+
Cl_
![Page 236: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/236.jpg)
2-58Efaroxan e·fa·roks·an
(±)-2-(2-Ethyl-2,3-dihydrobenzo[b]furan-2-yl)-2-imidazoline; C13H16N2O; 89197-32-0Efaroxan Hydrochloride 89197-00-2; RX 821037Alpha2-adrenoceptor antagonist
N
NH
OEt
and enantiomer
Efavirenz e·fa·vîr·renz(S)-6-Chloro-4-(cyclopropylethynyl)-1,4-dihydro-4-(trifluoromethyl)-3,1-benzoxazin-2-one; C14H9ClF3NO2; 154598-52-4; DMP 266; L-743; 5B706Antiviral
N
O
O
Cl
CF3
H
Eformoterol see Formoterol
Eflornithine ë·flor·ni·thën2-Difluoromethyl-DL-ornithine; C6H12F2N2O2; 67037-37-0; MDL 71782AAntiprotozoan
H2NCOOH
NH2F2HC
and enantiomer
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2-59Efrotomycin ë·frö·tö·mï·sin
An antibiotic produced by Streptomyces lactamdurans and comprising three compo-nents: efrotomycin A1, efrotomycin A2 (an isomer of A1) and efrotomycin B;C59H88N2O20; 56592-32-6; MK 621; L-628313-000CEfrotomycin A1: (R)-2-{(2R,3R,4R,6S)-4-[6-Deoxy-4-O-(6-deoxy-2,4-di-O-methyl-a-L-manno-hexopyranosyl)-3-O-methyl-b-D-allo-hexopyranosyloxy]-2,3-dihydroxy-5,5-dimethyl-6-[(1E,3Z)-penta-1,3-dienyl]perhydropyran-2-yl}N-[(2Z,4E)-(6S,7R)-7-{(2S,3S,4R,5R)-5-[(1E,3E,5E)-7-(1,2-dihydro-4-hydroxy-1-methyl-2-oxo-3-pyridyl)-6-methyl-7-oxohepta-1,3,5-trienyl]tetrahydro-3,4-dihydroxy-2-furyl}6-methoxy-5-methylocta-2,4-dienyl]butyramideEfrotomycin A2: As for efrotomycin A1, except that for ‘(1E,3E,5E)’ read‘(1E,3E,5Z)’Efrotomycin B: (R)-2-{(2R,3R,4R,6S)-4-[6-Deoxy-4-O-(6-deoxy-2,4-di-O-methyl-a-L-mannohexopyranosyl)-3-O-methyl-b-D-allo-hexopyranosyloxy]-2,3-dihydroxy-5,5-dimethyl-6-[(1E,3Z)-penta-1,3-dienyl]perhydropyran-2-yl}N-[(2Z,4E)-(6S,7R)-7-{(2S,3S,4R,5R)-5-[(1E,3E)-4-(3,4,5,6-tetrahydro-3,6-dimethyl-4,5-dioxo-2H-pyrano[3,2-c]pyridin-2-yl)buta-1,3-dienyl]tetrahydro-3,4-dihydroxy-2-furyl}6-methoxy-5-methylocta-2,4-dienyl]butyramideAntibiotic (veterinary)
R = R1 =
ORH O
Me
OMe
MeO
Et
OH
OH
Me
Me
CH3
NOR1
OH OH
OMe
OMe
OH
O
O
OMe
HO
MeOMe
NMe
O
O OH
Me
Eletriptan e·lë·trip·tan(R)-2-[3-(1-Methylpyrrolidin-2-ylmethyl)indol-5-yl]ethyl phenyl sulfone;C22H26N2O2S; 143322-58-1; UK-116,044Eletriptan Hydrobromide UK-116,044-045HT1D-Serotonin receptor agonist
O OS
NH
N
H
Me
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2-60Elliptinium Acetate e·lip·ti·në·um
9-Hydroxy-2,5,11-trimethyl-6H-pyrido[4,3-b]carbazolium acetate; C20H20N2O3;58337-35-2Cytotoxic
N
NMe
Me
Me
HO
H
OCOCH3
+_
Embramine em·bra·mën2-(4-Bromo-a-methylbenzhydryloxy)ethyldimethylamine; C18H22BrNO; 3565-72-8Histamine H1-receptor antagonist
ONMe2
BrMe
and enantiomer
Embutramide em·bú·tra·mïdN-(b,b-Diethyl-m-methoxyphenethyl)-4-hydroxybutyramide; C17H27NO3; 15687-14-6Opioid analgesic
NMeOEt Et
O
OH
H
Emedastine e·me·das·tën1-(2-Ethoxyethyl)-2-(4-methyl-1H-1,4-diazepan-1-yl)benzimidazole; C17H26N4O;87233-61-2Emedastine Fumarate (1:2) 87233-62-3; EMADINE
Histamine H1-receptor antagonist; antiallergic
N
N NMeN
O CH3
Emepronium Bromide e·me·prö·në·umEthyldimethyl(1-methyl-3,3-diphenylpropyl)ammonium bromide; C20H28BrN; 3614-30-0Anticholinergic
H Me
NMe2
Et
and enantiomer
Br_
+
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2-61Emepronium Carrageenate (BAN) e·me·prö·në·um ka·ra·gë·nät
The ethyldimethyl(1-methyl-3,3-diphenylpropyl)ammonium salt of carrageenan, alinear polysaccharide of sulfated galactose and 3,6-anhydrogalactose residuesexisting in two principal fractions (k-and l-carrageenan); CETIPRIN NOVUMAnticholinergic
Emetine (BAN) e·me·tën6¢,7¢,10,11-Tetramethyoxyemetan; C29H40N2O4; 483-18-1�Emetine Hydrochloride 316-42-7Antiprotozoan
N
H
Et
HN
MeO
MeO
H
H
OMe
OMe
H
Emiglitate ë·mig·li·tätEthyl 4-{2-[(2R,3R,4R,5S)-3,4,5-trihydroxy-2-(hydroxymethyl)-piperidino]ethoxy}benzoate; C17H25NO7; 80879-63-6; BAY o 1248Glucosidase inhibitor
O
OEt
O
HO
HO
OH
OH
N
Emylcamate e·mil·ka·mät1-Ethyl-1-methylpropyl carbamate; C7H15NO2; 78-28-4Tranquilliser; muscle relaxant
H2N O
Me EtCH3
O
Enalapril ë·na·la·prilN-{N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl}-L-proline; C20H28N2O5;75847-73-3Enalapril Maleate 76095-16-4; ¨̈̈̈̈CARDIOVET; INNOVACE; INNOZIDE*Angiotensin-converting enzyme inhibitor
HN
O
MeH
COOHH
NH
EtOOC
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2-62Enalaprilat ë·na·la·pri·lat
N-{N-[(S)-1-Carboxy-3-phenylpropyl]-L-alanyl}-L-proline; C18H24N2O5; 76420-72-9; MK-422Angiotensin-converting enzyme inhibitor
HN
O
MeH
COOHH
NH
HOOC
Enbucrilate en·bú·kri·lätButyl 2-cyanoacrylate; C8H11NO2; 6606-65-1; HISTOACRYLSurgical tissue adhesive
H2CO CH3
CN
O
Encainide en·kã·nïd2¢-[2-(1-Methyl-2-piperidyl)ethyl]-p-anisanilide; C22H28N2O2;37612-13-8; MJ 9067-1Antiarrhythmic
N
N
MeO
O
Me
H
Enciprazine en·si·pra·zën1-(4-o-Methoxyphenylpiperazin-1-yl)-3-(3,4,5-trimethoxyphenoxy)propan-2-ol;C23H32N2O6; 68576-86-3; Wy 48624Enciprazine Hydrochloride 68576-88-5Anxiolytic
O NH OH N
MeO
MeO
MeO
MeO
and enantiomer
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2-63Endralazine en·dra·la·zën
6-Benzoyl-5,6,7,8-tetrahydropyrido[4,3-c]pyridazin-3-ylhydrazine; C14H15N5O;39715-02-1; BQ 22-708Vasodilator
N
NN
O
NH NH2
Enflurane en·flûr·rän2-Chloro-1,1,2-trifluoroethyl difluoromethyl ether; C3H2ClF5O;13838-16-9; ALYRANE; ETHRANEAnaesthetic
F O
F F FCl
FH
and enantiomer
Enilconazole e·nil·ko·na·zôl(RS)-Allyl 1-(2,4-dichlorophenyl)-2-(imidazol-1-yl)ethyl ether;imazalil (BSI/ISO); C14H14Cl2N2O; 73790-28-0; 35554-44-0; ̈ IMAVEROLAntifungal (veterinary)
OCH2N
NCl
Cl
H
and enantiomer
Eniluracil e·nil·ûr·ra·sil5-Ethynylpyrimidine-2,4(1H,3H)-dione; C6H4N2O2; 59989-18-3Uracil reductase inhibitor; antineoplastic
NH
N O
OHC
H
Enoxacin e·noks·a·sin1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-(piperazin-1-yl)-1,8-naphthyridine-3-carboxylic acid; C15H17FN4O3; 74011-58-8; COMPRECINAntibacterial
HN
N N N
F
O
Et
COOH
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2-64�Enoxaparin Sodium ë·noks·a·pa·rin
A low-molecular-weight heparin, bearing at the non-reducing end of its chain a(3R,4S)-3,4-dihydro-4-hydroxy-6-(sodio-oxycarbonyl)-3-(sodio-oxysulfonyloxy)-2H-pyran-2-yl group; CLEXANEAnticoagulant
Enoximone e·noks·i·mön4-Methyl-5-[4-(methylthio)benzoyl]-4-imidazolin-2-one; C12H12N2O2S; 77671-31-9;PERFANCardiac stimulant
N
NO
MeMeS
OH
H
Enoxolone e·noks·o·lön3b-Hydroxy-11-oxo-olean-12-en-30-oic acid; C30H46O4; 471-53-4Treatment of skin diseases
MeH
MeMe
HO
O
H
Me
COOHMe
HMe Me
Enpiprazole en·pip·ra·zôl1-(2-Chlorophenyl)-4-[2-(1-methylpyrazol-4-yl)ethyl]piperazine; C16H21ClN4;31729-24-5Psychotropic
N NCl
N
N
Me
Enprostil en·pros·til(1) Methyl (E)-(11R,15R)-11,15-dihydroxy-9-oxo-16-phenoxy-17,18,19,20-tetranorprosta-4,5,13-trienoate; (2) methyl 7-{(E)-(1R*,2R*,3R*)-3-hydroxy-2-[(3R*)-3-hydroxy-4-phenoxybut-1-enyl]-5-oxocyclopentyl}hepta-4,5-dienoate;C23H28O6; 73121-56-9; RS 84135Gastric antisecretory
O
H
HOHHHO
C
OCOOH
and enantiomer
![Page 243: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/243.jpg)
2-65Enrofloxacin en·ro·floks·a·sin
1-Cyclopropyl-7-(4-ethylpiperazin-1-yl)-6-fluoro-1,4-dihydro-4-oxoquinoline-3-carboxylic acid; C19H22FN3O3; 93106-60-6; ̈ BAYTRILAntibacterial (veterinary)
NN
NEt
F
O
COOH
Entacapone en·ta·ka·pön(E)-2-Cyano-3-(3,4-dihydroxy-5-nitrophenyl)-N,N-diethylacrylamide; C14H15N3O5;130929-57-6; COMTESS
Antiparkinsonian
NEt2
H
CN
O
HO
OH
O2N
Epanolol e·pa·no·lol(RS)-N-[2-(3-o-Cyanophenoxy-2-hydroxypropylamino)ethyl]-2-(4-hydroxyphenyl)acetamide; C20H23N3O4; 86880-51-5; ICI 141,292Beta-adrenoceptor antagonist
NN
HOO H OH
O
NCH
H
and enantiomer
�Ephedrine (BAN) e·fe·drën(1R,2S)-2-Methylamino-1-phenylpropan-1-ol; C10H15NO;299-42-3 (anhydrous); 50906-05-3 (hemihydrate); FRANOL EXPECT*�Ephedrine Hydrochloride 50-98-6; CAM; component in many proprietarypreparationsEphedrine Sulphate 134-72-5; FRANOL PLUS*Sympathomimetic
NHMeH OH
H Me
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2-66Epicillin e·pi·si·lin
(6R)-6-(a-D-Cyclohexa-1,4-dienylglycylamino)penicillanic acid; C16H21N3O4S;26674-90-3Antibacterial
N
NO
H2N H
O
S
H COOH
Me
Me
H HH
Epiestriol (epioestriol) e·pë·ës·trë·olEstra-1,3,5(10)-triene-3,16b,17b-triol; C18H24O3; 547-81-9Oestrogen
HH
Me
H
HO
OH
OH
Epimestrol e·pi·mës·trol3-Methoxyestra-1,3,5(10)-triene-16a,17a-diol; C19H26O3; 7004-98-0;Org 817Oestrogen
HH
Me
H
MeO
OH
H
OH
Epioestriol see Epiestriol
Epirubicin e·pi·roo·bi·sin(8S,10S)-10-(3-Amino-2,3,6-trideoxy-a-L-arabino-hexopyranosyloxy)-8-glycolloyl-7,8,9,10-tetrahydro-6,8,11-trihydroxy-1-methoxynaphthacene-5,12-dione;C27H29NO11; 56420-45-2Epirubicin Hydrochloride 56390-09-1; PHARMORUBICINCytotoxic
O
OOMe
OH
OH
O
OH
H
HO
O
NH2
Me
OOH
![Page 245: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/245.jpg)
2-67Epitizide (epithiazide) e·pi·tï·zïd
6-Chloro-3,4-dihydro-3-(2,2,2-trifluoroethylthiomethyl)-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; C10H11ClF3N3O4S3; 1764-85-8Diuretic
H2N
O OS
O OS
ClCF3S
NH
NHH
and enantiomer
Epitumomab e·pi·tü·mö·mabMouse IgG 1 monoclonal antibody (HMFG1) that binds the human muc-1 geneproduct; 263547-71-3Antineoplastic
Epoetin Alfa e·pö·e·tin al·faRecombinant human erythropoietin derived from a cloned human erythropoietingene; C809H1301N229O240S5 (non-glycosylated protein); 113427-24-0; EPREXHaematopoietic growth factor
For labelling purposes, the following three letter code, to indicate the method ofproduction, is approved:
(rch) produced from genetically engineered Chinese hamster ovary cells
epoetin Alfa has the following glycosylated amino acid sequence:
APPRLICDSR VLERYLLEAK EAENITTGCA
EHCSLNENIT VPDTKVNFYA WKRMEVGQQA
VEVWQGLALL SEAVLRGQAL LVNSSQPWEP
LQLHVDKAVS GLRSLTTLLR ALGAQKEAIS
PPDAASAAPL RTITADTFRK LFRVYSNFLR
GKLKLYTGEA CRTGD
Epoetin Beta e·pö·e·tin bë·taRecombinant human erythropoietin, derived from a cloned human erythropoietingene, having the same amino acid sequence as epoetin alfa but differing in theglycosylation pattern; C809H1301N229O240S5 (non-glycosylated protein); 122312-54-3;RECORMONHaematopoietic growth factor
For labelling purposes, the following three letter code, to indicate the method ofproduction, is approved:
(rch) produced from genetically engineered Chinese hamster ovary cells
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2-68Epoetin Gamma e·pö·e·tin ga·ma
Recombinant human erythropoietin derived from a cloned human erythropoetingene and having the same amino acid sequence as epoetin alfa but differing in theglycosylation pattern; C809H1301N229O240S5 (non-glycosylated protein); 130455-76-4;BI 71·052Haematopoietic growth factor
For labelling purposes, the following three letter code, to indicate the method ofproduction, is approved:
(rch) produced from genetically engineered Chinese hamster ovary cells
Epoprostenol Sodium (INNM) e·pö·pros·te·nol(1) Sodium (Z)-5-{(3aR,4R,5R,6aS)-5-hydroxy-4-[(E)-(3S)-3-hydroxyoct-1-enyl]perhydrocyclopenta[b]furan-2-ylidene}valerate; (2) sodium (5Z,13E)-(9S,11R,15S)-6,9-epoxy-11,15-dihydroxyprosta-5,13-dienoate; prostacyclinsodium; C20H31NaO5; 61849-14-7; FLOLANProstanoid anticoagulant and vasodilator
CH3
H OHHHO
O
NaOOC H
HH
Epostane e·pö·stän4a,5a-Epoxy-3,17b-dihydroxy-4b,17a-dimethyl-5a-androst-2-ene-2-carbonitrile;C22H31NO3; 80471-63-2; WIN 32729Oxytocic
HH
Me
HMeNC
HOOMe
Me
OH
Epristeride ë·pris·te·rïd17b-(tert-Butylcarbamoyl)androsta-3,5-diene-3-carboxylic acid; C25H37NO3;119169-78-7; SK&F 1056575-Alpha-reductase inhibitor; treatment and control of benign prostate hypertrophy
HOOC
Me
Me
HH
HH
CONHBu t
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2-69Eprosartan e·prö·sar·tan
(E)-a-{2-Butyl-5-[2-carboxy-3-(2-thienyl)prop-1-enyl]-1H-imidazol-1-yl}-p-toluicacid; C23H24N2O4S; 133040-01-4; SK&F 108566Eprosartan Mesilate 133040-01-4; SK&F 108566-JAngiotensin II antagonist; antihypertensive
SH3C
N
N
COOH
COOH
Epsiprantel ep·si·pran·tel2-Cyclohexylcarbonyl-1,2,3,4,6,7,8,12b-octahydropyrazino-[2,1-a][2]benzazepin-4-one; C20H26N2O2; 98123-83-2; BRL 38705Anthelmintic
N
N
O
O
H
and enantiomer
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2-70Eptacog Alfa (Activated) ep·ta·kog al·fa
Blood-coagulation factor VII (human clone lHVII2463 protein moiety);C2621H4056N728O812S36; 102786-52-7; NOVOSEVEN
Haemostatic
eptacog alfa has the following amino acid sequence:
ANAFLγ γLRP GSLVRVCKVV QCSFVVARVI
FKDAVRTKLF WISYSDGDQC ASSPCQNGGS
CKβQLQSYIC FCLPAFEGRN CETHKDDQLI
CVNENGGCEQ YCSDHTGTKR SCRCHEGYSL
LAVGVSCTPT VEYPCGKIPI LEKRNASKPQ
GRIVGGKVCP KGECPWQVLL LVNGAQLCGG
TLINTIWVVS AAHCFDKIKN WRNLIAVLGE
HDLSEHDGDE QSRRVAQVII PSTYVPGTTN
HDIALLRLHQ PVVLTDHVVP LCLPERTFSE
RTLAFVRFSL VSGWGQLLDR GATALELMVL
NVPRLMTQDC LQQSRKVGDS PNITEYMFCA
GYSDGSKDSC KGDSGGPHAT HYRGTWYLTG
IVSWGQGCAT VGHFGVYTRV SQYIEWLQKL
MRSEPRPGVL LRAPFP
*
*
* = glycosylation siteb = b-hydroxyaspartic acidg = g-carboxyglutamic acid
Eptifibatide ep·ti·fi·ba·tïdS1,S6-Cyclo[N6-carbamimidoyl-N2-(3-sulfanylpropanoyl)-L-lysylglycyl-L-a-aspartyl-L-tryptophyl-L-prolyl-L-cysteinamide]; C35H49N11O9S2; 148031-34-9; 157630-07-4
N6Lys–Gly–Asp–Trp–Pro–Cys–NH2
HN NH2
O
S
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2-71Erbulozole er·bü·lo·zôl
Ethyl (2RS, 4RS)-4-[2-(imidazol-1-ylmethyl)-2-(4-methoxyphenyl)-1,3-dioxolan-4-ylmethylthio]carbanilate; C24H27N3O5S; 124784-31-2;R 55104Antineoplastic (radiosensitizer)
H
N
N
OO
OMe
NCOOEt
SH
and enantiomer
�Ergocalciferol er·gö·kal·si·fe·rol(5Z,7E)-(3S)-9,10-Secoergosta-5,7,10(19),22-tetraen-3-ol; vitamin D2; calciferol;C28H44O; 50-14-6; component in many proprietary preparationsVitamin D analogue
HO
MeH
MeH MeH
CH2
H
Me
Me
H
Ergometrine er·gö·me·trën(1) 9,10-Didehydro-N-[(S)-2-hydroxy-1-methylethyl]-6-methylergoline-8b-carboxamide; (2) N 8-(2-hydroxy-1-methylethyl)-D-lysergamide; C19H23N3O2; 60-79-7�Ergometrine Maleate ergonovine maleate (USAN); 129-51-1; SYNTOMETRINE*Oxytocic
MeH
N
HN NCH3
HO
OH
H
H
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2-72Ergotamine er·go·ta·mën
(5¢S)-5¢-Benzyl-9,10-dihydro-12¢-hydroxy-2¢-methyl-3¢,6¢,18-trioxoergotaman;C33H35N5O5; 113-15-5�Ergotamine Tartrate 379-79-3; CAFERGOT*; LINGRAINE; MEDIHALER-ERGOT-AMINE; MIGRIL*Vasoconstrictor
NO
NOO
OH
H
H
Me
NH
O
HN
NH
Me
H
�Erythromycin e·ri·thrö·mï·sinA mixture of macrolide antibiotics produced by a strain of Streptomyces erythreus.The major component is erythromycin A·Erythromycine A: (2R,3S,4S,5R,6R,8R, 10R,11R,12S,13R)-5-(3-amino-3,4,6-trideoxy-N,N-dimethyl-b-D-xylo-hexopyranosyloxy)-3-(2,6-dideoxy-3-C,3-O-dimethyl-a-L-ribo-hexopyranosyloxy)-13-ethyl-6,11,12-trihydroxy-2,4,6,8,10,12-hexamethyl-9-oxotridecan-13-olide; C37H67NO13; 114-07-8; BENZAMYCIN*;ERYCEN; ERYMAX; RETCIN; STIEMYCIN; TILORYTH; ZINERYT*�Erythromycin Ethyl Succinate 41342-53-4; ARPIMYCIN; ERYMIN;ERYTHROPED; ERYTHROCIN�Erythromycin Lactobionate 3847-29-8; ERYTHROCIN LACTOBIONATE�Erythromycin Stearate 643-22-1; ERYTHROCINErythromycin Thiocyanate 7704-67-8; ¨ERYTHROCIN PREMIX; ¨MYCOSAN-T*;Antibacterial
OO
EtMe
HO
HO
MeOH
Me
Me
Me
O
NMe2
Me
OH
O
O
Me
O
HO
Me
OMeOMe
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2-73�Erythromycin Estolate (INNM)
Erythromycin 2¢-propionate dodecyl sulfate; C40H71NO14·C12H26O4S;3521-62-8; ILOSONEAntibacterial
OO
EtMe
HO
HO
MeOH
Me
Me
Me
O
NMe2
Me
O
O
O
Me
O
CH3
OHO
Me
OMeOMe
•CH3[ CH2] 11OSO3H
�Erythropoetin see Epoetin Afa, Epoetin Beta and Epoetin Gamma
Esflurbiprofen es·flûr·bï·prö·fen(S)-2-(2-Fluorobiphenyl-4-yl)propionic acid; C15H13FO2; 51543-39-6;BTS 24332Analgesic; anti-inflammatory
COOH
H MeF
Esketamine es·ke·ta·mën(S)-2-(2-Chlorophenyl)-2-(methylamino)cyclohexanone; C13H16ClNO; 33643-46-8Anaesthetic
OCl
NHMe
Esmolol es·mo·lolMethyl 3-[4-(2-hydroxy-3-isopropylaminopropoxy)phenyl]propionate; C16H25NO4;84057-94-3; ASL-8052-001Esmolol Hydrochloride 81161-17-3; BREVIBLOCBeta-adrenoceptor antagonist
MeOOC
O NHPriH OH
and enantiomer
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2-74Espatropate es·pa·trö·pät
(R)-Quinuclidin-3-yl (R)-3-hydroxy-2-1H-(imidazol-1-yl)-2-phenylpropionate;C19H23N3O3; 132829-83-5; UK-88060Antimuscarinic; bronchodilator
N
OO
N
N
H
CH2OH
Estradiol (oestradiol) ë·stra·dï·olEstra-1,3,5(10)-triene-3,17b-diol; C18H24O2; 50-28-2; ELLEST DUET*; ELLESTSOLO; ESTRACOMBI*; ESTRADERM; ESTRAPAK*; ESTRING*; EVOREL; FEMAPAK*;FEMOSTON*; FEMSEVEN; HORMONIN*; ¨ IMPLIXA*; KLIOFEM*; MENOREST;OESTROGEL; TRISEQUENS*; VAGIFEM; ZUMENON�Estradiol Benzoate 50-50-0; BENZTRONE; ¨DELPLEX*; ¨MESALIN; ¨PRID*Estradiol Valerate 979-32-8; CLIMAGEST*; CLIMAVAL; CLIMESSE*; CYCLO-PROGYNOVA*; NUVELLE*; PROGYNOVA; TRIDESTRA*Oestrogen
HO
H
H
H
OH
HMe
Estramustine ës·tra·mus·tën17b-Hydroxyestra-1,3,5(10)-trien-3-yl 3-bis(2-chloroethyl)carbamate;C23H31Cl2NO3; 2998-57-4�Estramustine Sodium Phosphate 52205-73-9; ESTRACYTCytotoxic
H
H
H
Me OH
H
ON
O
Cl
Cl
Estriol (oestriol) ës·trë·olEstra-1,3,5(10)-triene-3,16a,17b-triol; C18H24O3;50-27-1; HORMONIN*; ORTHO-GYNEST; OVESTIN; TRISEQUENS*Oestrogen
HO
H
H
H
OH
HMe
OH
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2-75Estriol Sodium Succinate
Disodium 3-hydroxy-estra-1,3,5(10)-triene-16a,17b-diyl disuccinate; C26H30Na2O9;113-22-4Oestrogen
HO
H
H
H
HMe OCOCH2CH2COONa
OCOCH2CH2COONa
Estriol Succinate3-Hydroxy-estra-1,3,5(10)-triene-16a,17b-diyl di(hydrogen succinate); C26H32O9;514-68-1Oestrogen
HO
H
H
H
HMe OCOCH2CH2COOH
OCOCH2CH2COOH
Estrone (oestrone) ës·trön3b-Hydroxyestra-1,3,5(10)-trien-17-one; C18H22O2; 53-16-7; HORMONIN*Oestrogen
HO
H
H
H
Me O
Estropipate ës·trö·pi·pät17-Oxoestra-1,3,5-(10)-trien-3-yl hydrogen sulfate— piperazine (1:1); piperazineoestrone sulfate; C18H22O5S·C4H10N2; 7280-37-7; HARMOGEN; IMPROVERA
Oestrogen
N
NH
Me
H H
HO3SO
O H
H
+
�Etacrynic Acid (ethacrynic acid) e·ta·krï·nik[2,3-Dichloro-4-(2-ethylacryloyl)phenoxy]acetic acid; C13H12Cl2O4;58-54-8; EDECRINDiuretic
O COOH
H3C
O
CH2
Cl
Cl
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2-76�Etafedrine e·ta·fe·drën
2-(Ethylmethylamino)-1-phenylpropan-1-ol; C12H19NO; 7681-72-0
NEtHO H
H Me
Me
mixture of stereoisomers
Etamiphylline e·ta·mi·fi·lën7-(2-Diethylaminoethyl)theophylline; C13H21N5O2; 314-35-2�Etamiphylline Camsilate 19326-29-5; ¨DALOPHYLLINE; ¨̈̈̈̈MILLOPHYLLINE-VBronchodilator
NMe
Me
O
O
N
N
N
NEt2
Etamivan (ethamivan) e·ta·mi·vanN,N-Diethylvanillamide; C12H17NO3; 304-84-7; CLAIRVANCentral nervous system stimulant
CONEt2
HO
OMe
Etamsylate (ethamsylate) e·tam·si·lätDiethylammonium 2,5-dihydroxybenzenesulfonate; C6H6O5S·C4H11N;2624-44-4; DICYNENEHaemostatic
SO3
OH
HO
EtNH3+
_
Etebenecid (ethebenecid) et·ë·be·ne·sid4-Diethylsulfamoylbenzoic acid; C11H15NO4S; 1213-06-5Uricosuric
SO2NEt2
HOOC
Etenzamide see Ethenzamide
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2-77Etanercept e·tan·er·sept
1–235-Tumour necrosis factor receptor (human) fusion protein with 236–467-immunoglobulin G1 (human) g1-chain Fc fragment, dimer;C 2224H3472N618O701S36 (non-glycosylated protein monomer); 185243-69-0Immunomodulator
etanercept has the following amino acid sequence:LPAQVAFTPY APEPGSTCRL REYYDQTAQM
CCSKCSPGQH AKVFCTKTSD TVCDSCEDST
YTQLWNWVPE CLSCGSRCSS DQVETQACTR
EQNRICTCRP GWYCALSKQE GCRLCAPLRK
CRPGFGVARP GTETSDVVCK PCAPGTFSNT
TSSTDICRPH QICNVVAIPG NASMDAVCTS
TSPTRSMAPG AVHLPQPVST RSQHTQPTPE
PSTAPSTSFL LPMGPSPPAE GSTGDEPKSC
DKTHTCPPCP APELLGGPSV FLFPPKPKDT
LMISRTPEVT CVVVDVSHED PEVKFNWYVD
GVEVHNAKTK PREEQYNSTY RVVSVLTVLH
QDWLNGKEYK CKVSNKALPA PIEKTISKAK
GQPREPQVYT LPPSREEMTK NQVSLTCLVK
GFYPSDIAVE WESNGQPENN YKTTPPVLDS
DGSFFLYSKL TVDKSRWQQG NVFSCSVMHE
ALHNHYTQKS LSLSPGK 2
Eterobarb e·te·rö·barb5-Ethyl-1,3-bis(methoxymethyl)-5-phenylperhydropyrimidine-2,4,6-trione;C16H20N2O5; 27511-99-5Anticonvulsant
N
N
Et
O
OMe
O
OMe
O
Ethacrynic Acid see Etacrynic Acid
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2-78Ethambutol e·tham·bü·tol
(S,S)-N,N¢-Ethylenebis(2-aminobutan-1-ol); C10H24N2O2; 74-55-5�Ethambutol Hydrochloride 1070-11-7; MYAMBUTOLAntitubercular
H3CN
NCH3
OH
OH
H
H
H
H
Ethamivan see Etamivan
Ethamsylate see Etamsylate
Ethchlorvynol eth·klor·vï·nol1-Chloro-3-ethylpent-1-en-4-yn-3-ol; C7H9ClO; 118-18-8Hypnotic
CH3
HO
HC
Cl
and enantiomer
Ethebenecid see Etebenecid
Ethenzamide (etenzamide) e·then·za·mïd2-Ethoxybenzamide; C9H11NO2; 938-73-8Analgesic
CONH2
OEt
Ethiazide e·thï·a·zïd(RS)-6-Chloro-3-ethyl-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; C9H12ClN3O4S2; 1824-58-4Diuretic
H2N
O OS
O OS
NH
NH
Cl Et
H
and enantiomer
Ethinamate e·thi·na·mät1-Ethynylcyclohexyl carbamate; C9H13NO2; 126-52-3Hypnotic
O
NH2O
CH
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2-79�Ethinylestradiol (ethinyloestradiol) e·thi·nïl·ë·stra·dï·ol
19-Nor-17a-pregna-1,3,5(10)-trien-20-yne-3,17b-diol; C20H24O2;57-63-6; component in many proprietary preparationsOestrogen
HO
H
H
H
Me OH
CH
��Ethionamide2-Ethylpyridine-4-carbothioamide; C8H10N2S; 536-33-4
N
NH2
S
Et
Ethisterone e·thi·ste·rön17b-Hydroxy-17a-pregn-4-en-20-yn-3-one; C21H28O2; 434-03-7Progestogen
O
H
H
H
Me OH
CHMe
Ethoglucid see Etoglucid
Ethoheptazine e·thö·hep·ta·zënEthyl 1-methyl-4-phenylperhydroazepine-4-carboxylate; C16H23NO2;77-15-6Ethoheptazine Citrate 2085-42-9; EQUAGESIC*;Opioid analgesic
N
COOEt
Me
Ethomoxane e·thö·moks·än(RS)-Butyl(8-ethoxy-1,4-benzodioxan-2-ylmethyl)amine; C15H23NO3;16509-23-2Alpha-adrenoceptor antagonist
O
O
OEt
NHBunH
and enantiomer
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2-80�Ethopabate (BAN) e·thö·pa·bät
Methyl 4-acetamido-2-ethoxybenzoate; C12H15NO4; 59-06-3;¨AMPROLMIX-UK*; ¨AMPROL-PLUS*Coccidiostat
COOMe
OEtAcHN
Ethopropazine see Profenamine
Ethosalamide see Etosalamide
�Ethosuximide e·thö·suk·si·mïd(RS)-2-Ethyl-2-methylsuccinimide; C7H11NO2; 77-67-8; EMESIDE; ZARONTINAnticonvulsant
HNO O
MeEt
and enantiomer
�Ethotoin3-Ethyl-5-phenylhydantoin; C11H12N2O2; 86-35-1
HN
NO O
Et
H
and enantiomer
Ethybenztropine see Etybenzatropine
Ethyl Biscoumacetate bis·koo·ma·së·tätEthyl bis(4-hydroxy-2-oxo-2H-chromen-3-yl)acetate; C22H16O8;548-00-5Anticoagulant
OOOO
OH OHCOOEt
�Ethyl DibunateEthyl 3,6-di-tert-butylnaphthalene-1-sulfonate; C20H28O3S; 5560-69-0
SO3Et
Bu tBu t
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2-81Ethyl Pyrophosphate pï·rö·fos·fät
Tetraethyl pyrophosphate; TEPP; C8H20O7P2Treatment of myasthenia gravis
Ethylestrenol (ethyloestrenol) ë·thïl·ës·tre·nol19-Nor-17a-pregn-4-en-17b-ol; C20H32O; 965-90-2; ̈ NANDORALAnabolic steroid; androgen
HH
Me
HH
Et
OH
Ethylmethylthiambutene ë·thïl·më·thïl·thï·am·bü·tën[3,3-Di-(2-thienyl)-1-methylprop-2-enyl]ethylmethylamine; C15H19NS2;441-61-2Opioid analgesic
and enantiomer
MeH
Et
MeN
S S
Ethylmorphine (BAN) ë·thïl·mor·fën7,8-Didehydro-4,5-epoxy-3-ethoxy-17-methylmorphinan-6-ol; C19H23NO3; 76-58-4�Ethylmorphine Hydrochloride 125-30-4Opioid analgesic
NMe
O
EtO
H
HO
Ethyloestrenol see Ethylestrenol
Ethynodiol see Etynodiol�Etidocaine e·tï·dö·kän2-(N-Ethylpropylamino)butyro-2¢,6¢-xylidide; C17H28N2O; 36637-18-0Local anaesthetic
NN
Et
O Prn
H Et
Me
MeH
and enantiomer
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2-82Etidronic Acid e·ti·dron·ik
1-Hydroxyethylidenedi(phosphonic acid); C2H8N7P2; 2809-21-4Disodium Etidronate 7414-83-7; DIDRONELCalcification inhibitor; used in the treatment of Paget’s disease
P
O
OH
OHP
O
OH
HO C
OH
Me
Etifenin e·ti·fen·in2,6-Diethylphenylcarbamoylmethyliminodi(acetic acid); C16H22N2O5;63245-28-3; SOLCO HIDA; SOLCOSCINT HEPATOBIDA; TECHNETIUM (EHIDA)AGENTDiagnostic aid
NN
OMe
Me
COOH
COOH
H
�Etifoxine (etifoxin)(RS)-6-Chloro-4-methyl-4-phenyl-4H-3,1-benzoxazin-2-yl(ethyl)amine;C17H17ClN2O; 21715-46-8
N
O
MeCl
NHEt
and enantiomer
Etilefrine e·til·e·frën(RS)-2-Ethylamino-1-(3-hydroxyphenyl)ethanol; C10H15NO2 ; 709-55-7�Etilefrine Hydrochloride 943-17-9Sympathomimetic; antihypotensive
OH
NHEtH OH
and enantiomer
Etisazole e·tï·sa·zôl1,2-Benzothiazol-3-yl(ethyl)amine; C9H10N2S; 7716-60-1; ¨NETROSYLLAAntifungal
NS
NHEt
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2-83Etisomicin e·tï·sö·mï·sin
(1) 4-O-[(2S,3R)-cis-3-Amino-6-aminomethyl-3,4-dihydro-2H-pyran-2-yl]-2-deoxy-6-O-(3-deoxy-4-C-methyl-3-ethylamino-b-L-arabinopyranosyl)-D-streptamine; (2) 2-Deoxy-6-O-(3-deoxy-4-C-methyl-3-ethylamino-b-L-arabinopyranosyl)-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-a-D-glycero-hex-4-enopyranosyl)-D-streptamine; C20H39N5O7; 70639-484;BAY V1 4718Antitubercular
NH2
OH
O
O
H2N
OHO
O
NH2
HO
Me
NHEtH2N
�Etodolac e·tö·dö·lak1,8-Diethyl-1,3,4,9-tetrahydropyrano[3,4-b]indol-1-ylacetic acid; C17H21NO3;41340-25-4; LODINEAnalgesic; anti-inflammatory
NO
EtCOOH
EtH
Etofenamate e·tö·fe·na·mät2-(2-Hydroxyethoxy)ethyl N-(a,a,a-trifluoro-m-tolyl)anthranilate; C18H18F3NO4;30544-47-9Analgesic; anti-inflammatory
N
OO
OH
F3C
OH
�Etofylline e·to·fi·lën3,7-Dihydro-7-(2-hydroxyethyl)-1,3-dimethyl-1H-purine-2,6-dione; C9H12N4O3;519-37-9Bronchodilator
N
N
N
N
OHO
O
Me
Me
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2-84�Etoglucid (ethoglucid) et·ö·gloo·sid
1,2:15,16-Diepoxy-4,7,10,13-tetraoxahexadecane; C12H22O6; 1954-28-5
OO
OO O
O
Etomidate e·to·mi·dät(R)-Ethyl 1-(a-methylbenzyl)imidazole-5-carboxylate; C14H16N2O2;33125-97-2; HYPNOMIDATEHypnotic
N
N
COOEtMeH
Etonitazene e·tö·nï·ta·zën2-[2-(4-Ethoxybenzyl)-5-nitrobenzimidazol-1-yl]ethyldiethylamine; C22H28N4O3;911-65-9Opioid analgesic
N
N
OEtO2N
NEt2
Etonogestrel e·tö·nö·ges·trel17b-Hydroxy-11-methylene-18-homo-19-nor-17a-pregn-4-en-20-yn-3-one;C22H28O2; 54048-10-1; Org 3236Progestogen
O
H2C
H
H
OH
H
H
C CH
Et
Etoposide e·to·pö·sïd(5S,5aR,8aS,9S)-9-(4,6-O-Ethylidene-b-D-glucopyranosyloxy)-5,8,8a,9-tetrahydro-5-(4-hydroxy-3,5-dimethyoxyphenyl)isobenzofuro[5,6-f][1,3]benzodioxol-6(5aH)-one; C29H32O13; 33419-42-0; VP 16-213; VEPESIDCytotoxic
Me
H
O
O
OH
OH
O O
H
HH
H
O
OMe
OH
MeO
O
OO
`
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2-85Etorphine e·tor·fën
(1) (2R)-2-[(5R,6R,7R,14R)-4,5-Epoxy-3-hydroxy-6-methoxy-9a-methyl-6,14-ethenomorphinan-7-yl]pentan-2-ol; (2) (6R,7R,14R)-7,8-dihydro-7-[(1R)-1-hydroxy-1-methylbutyl]-6-O-methyl-6,14-ethenomorphine; C25H33NO4; 14521-96-1�Etorphine Hydrochloride 13764-49-3; ¨ IMMOBILON*Opioid analgesic
NMe
O
HO
HMe
HO
MeO
CH3
Etosalamide (ethosalamide) e·tö·sa·la·mïd2-(2-Ethoxyethoxy)benzamide; C11H15NO3; 15302-15-5Analgesic; antipyretic
OO CH3
CONH2
Etoxeridine e·toks·e·ri·dënEthyl 1-[2-(2-hydroxyethoxy)ethyl]-4-phenylpiperidine-4-carboxylate; C18H27NO4;469-82-9Opioid analgesic
NO
OH
COOEt
�Etretinate ë·tre·ti·nät(1) Ethyl 3-methoxy-15-apo-j-caroten-15-oate; (2) ethyl (all-trans)-9-(4-methoxy-2,3,6-trimethylphenyl)-3,7-dimethylnona-2,4,6,8-tetra-enoate; C23H30O3; 54350-48-0Treatment of psoriasis
COOEt
Me
Me
Me
MeO
Me Me
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2-86Etryptamine ë·trip·ta·mën
1-(Indol-3-ylmethyl)propylamine; a-ethyltryptamine; C12H16N2;2235-90-7Antidepressant
N
EtH NH2
H
and enantiomer
Etybenzatropine (ethybenztropine) e·të·ben·za·trö·pën(1R,3r,5S)-3-Benzhydryloxy-8-ethylnortropane; C22H27NO; 524-83-4Anticholinergic
NEt
O
Etynodiol (ethynodiol) ë·tï·nö·dï·ol19-Nor-17a-pregn-4-en-20-yne-3b,17b-diol; C20H28O2; 1231-93-2�Etynodiol Diacetate 297-76-7; FEMULEN*Progestogen
HH
Me
HH
HO
OH
CH
Eucatropine ü·ka·trö·pën1,2,2,6-Tetramethyl-4-piperidyl mandelate; C17H25NO3; 100-91-4Mydriatic
O
O
N
Me
MeMeMe
OH
* * *
mixture of 8 stereoisomers
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2-87Eufauserase ü·for·se·räs
A broad-spectrum, monocomponent serine-protease enzyme, extracted andpurified from Euphausia superba (Antarctic krill); PHM-101Debridement of necrotic tissue
eufauserase has the following amino acid sequence:
AVENCGPVAP RNK
IVGGMEVTPH AYPWQVGLFI DDMYFCGGSI
ISDEWVLTAH CMDGAGFVEV VMGAHSIHDE
TEATQVRATS TDFFTHENWN SFTLSNDLAL
IKMPAPIEFN DVIOPVCLPT YTDASDDFVG
ESVTLTGWGK PSDSAFGIAE QLREVDVTTI
TTADCQAYYG IVTDKILCID SEGGHGSCNG
DSGGPMNYVT GGVTQTRGIT SFGSSTGCET
GYPDGYTRVT SYLDWIESNT GIAIDP
Chain A
Chain B
Euphausia Extract ü·for·së·aA purified extract from Euphausia superba (Antarctic krill) containing water-extractable macromolecules, mainly proteins in the molecular weight range 10-60kDa; the main action is due to the serine-proteases present with a molecular weightrange of 20-40 kDa.Debridement of necrotic tissue
Evicromil (BAN) ë·vi·krö·mil8-Ethyl-5-hydroxy-4-oxo-6-vinyl-4H-chromene-2-carboxylic acid; C14H12O5; 62571-88-4Prophylaxis of allergic conditions
O
O
COOH
OH
Et
H2C
Exametazime eks·a·me·ta·zëm(RS,RS)-3,3¢-(2,2-Dimethyltrimethylenedi-imino)di(butan-2-one oxime); 100551-63-1; C13H28N4O2; dl-HM-PAORadiodiagnostic aid to brain scintigraphy
HNH HN
N N
OH OH
Me Me
Me Me
MeMeH
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2-88Exemestane eks·ë·mes·tän
6-Methyleneandrosta-1,4-diene-3,17-dione; C20H24O2; 107868-30-4Aromatase inhibitor; treatment of advanced breast cancer
O
CH2
Me
H
H
H
Me O
Factor VIII (rDNA) see Octacog Alfa
Factor IX Fraction (BAN)A preparation of human blood containing coagulating factors II, IX and XMONONINE; REPLENINEAntihaemophilic
Famciclovir fam·sï·klö·veer2-[2-(2-Amino-9H-purin-9-yl)ethyl]trimethylene diacetate; C14H19N5O4; 104227-87-4; FAMVIRAntiviral
N
NN
N
OAc
OAcH2N
�Famotidine fa·mö·ti·dën3-[2-(Diaminomethyleneamino)-1,3-thiazol-4-ylmethylthio]-N-sulfamoylpropionamidine; C8H15N7O2S3; 76824-35-6; PEPCIDHistamine H2-receptor antagonist
S
NN
NH2
S NSO2NH2
NH2
H2N
Famprofazone fam·prö·fa·zön(RS)-4-Isopropyl-2-methyl-3-[methyl(a-methylphenethyl)aminomethyl]-1-phenyl-3-pyrazolin-5-one; C24H31N3O; 22881-35-2Analgesic; antipyretic
N NN
H Me
MePr i
O
Me
and enantiomer
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2-89Fanetizole fa·ne·ti·zôl
Phenethyl(4-phenyl-1,3-thiazol-2-yl)amine; C17H16N2S; 79069-94-6Fanetizole Mesilate 79069-95-7; CP-48810-27Immunoregulant
N
S NH
Fanthridone see Fantridone
Fantofarone fan·to·fa·rön3,4-Dimethoxyphenethyl{3-[4-(2-isopropylindolizin-1-ylsulfonyl)-phenoxy]propyl}(methyl)amine; C31H38N2O5S; 114432-13-2; SR 33557Calcium antagonist
NPr i
OMe
OMe
O OS
Me
NO
Fantridone (fanthridone) fan·tri·dön5-(3-Dimethylaminopropyl)phenanthridin-6(5H)-one; C18H20N2O;17692-37-4Antidepressant
N
O
NMe2
�Fazadinium Bromide1,1¢-Azobis(3-methyl-2-phenylimidazol[1,2-a]pyridinium) dibromide; C28H24Br2N6;49564-56-9
+ NN
Me
N+
_2BrN
N
Me
N
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2-90Febantel fe·ban·tel
2¢-[2,3-Bis(methoxycarbonyl)guanidino]-5¢-phenylthio-2-methoxyacetanilide;C20H22N4O6S; 58306-30-2; ̈ BAYVERMAnthelmintic
S
NNHCOOMe
NHCOOMe
NH
OOMe
�Felbinac fel·bi·nakBiphenyl-4-ylacetic acid; C14H12O2; 5728-52-9; CL 83544; TRAXAMAnti-inflammatory
COOH
�Felodipine fe·lö·di·pënEthyl methyl 4-(2,3-dichlorophenyl)-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate; C18H19Cl2NO4; 72509-76-3; PLENDILVasodilator
HN
Cl
Cl
COOMeEtOOC
MeMe
Felypressin fe·lë·pres·sin2-L-Phenylalanine-8-L-lysine-vasopressin; C46H65N13O11S2; 56-59-7; CITANESTWITH OCTAPRESSIN*Vasoconstrictor
Cys-Phe-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2
Fenbendazole fen·ben·da·zôlMethyl 5-(phenylthio)-1H-benzimidazol-2-ylcarbamate; C15H13N3O2S; 43210-67-9;¨̈̈̈̈CURAZOLE; ¨̈̈̈̈ FENDAZOLE; ¨̈̈̈̈ FLEXADIN; ¨ PANACUR; ¨̈̈̈̈WORMALIC; ¨̈̈̈̈WORMEX;¨̈̈̈̈ ZEROFENAnthelmintic
N
HNS NHCOOMe
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2-91Fenbenicillin (phenbenicillin) fen·be·ni·si·lin
(6R)-6-(2-Phenoxy-2-phenylacetamido)penicillanic acid; a-phenoxy-benzylpenicillin; C22H22N2O5S; 1926-48-3Antibiotic
HN
NOO
S
H COOH
Me
Me
H H
O
H*
and enantiomer at C*
�Fenbufen fen·bü·fen4-(Biphenyl-4-yl)-4-oxobutyric acid; C16H14O3; 36330-85-5; LEDERFENAnalgesic; anti-inflammatory
COOH
O
Fenbutrazate (phenbutrazate) fen·bü·tra·zät2-(3-Methyl-2-phenylmorpholino)ethyl 2-phenylbutyrate; C23H29NO3; 4378-36-3Fenbutrazate Hydrochloride 8004-38-4Appetite supressant
O
NO
O
H Me
Me
�FencamfaminN-Ethyl-3-phenylbicyclo[2.2.1]hept-2-ylamine; C15H21N; 1209-98-9
NHEt
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2-92Fenclorfos (fenclorphos) fen·klor·fos
O,O-Dimethyl O-(2,4,5-trichlorophenyl) phosphorothioate; C8H8Cl3O3PS; 299-84-3Insecticide
P
S
OMe
O
ClCl
Cl OMe
Fenclofenac fen·klö·fe·nak[2-(2,4-Dichlorophenoxy)phenyl]acetic acid; C14H10Cl2O3; 34645-84-6Analgesic; anti-inflammatory
O
Cl
ClCOOH
�Fenclozic Acid2-(4-Chlorophenyl)-1,3-thiazol-4-ylacetic acid; C11H8ClNO2S;17969-20-9
S
N
COOH
Cl
Fendosal fen·dö·sal5-(4,5-Dihydro-2-phenyl-3H-benz[e]indol-3-yl)salicylic acid; C25H19NO3; 53597-27-6; HP 129; P71·0129Analgesic; anti-inflammatory
N
OH
COOH
�Fenetylline (fenethylline)7-[2-(a-Methylphenethylamino)ethyl]theophylline; C18H23N5O2;3736-08-1
N
NN
N
N
H Me
O
O
Me
Me H
and enantiomer
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2-93Fenfluramine fen·flûr·ra·mën
Ethyl(a-methyl-3-trifluoromethylphenethyl)amine; C12H16F3N; 458-24-2�Fenfluramine Hydrochloride 404-82-0; PONDERAXAppetite suppressant
CH3
H NHEt
F3C
and enantiomer
Fenfluthrin fen·floo·thrin2,3,4,5,6-Pentafluorobenzyl (1R,3S)-3-(2,2-dichlorovinyl)-2,2-dimethyl-cyclopropanecarboxylate; C15H11Cl2F5O2; 75867-00-4Ectoparasiticide (veterinary)
Me
Me
H
Cl
Cl
HF
F
F
F
F
O
OH
Fengabine fen·ga·bën(Z)-a-Butylimino-4-chloro-a-(2-chlorophenyl)-o-cresol; C17H17Cl2NO; 80018-06-0;SL 79·229-00Antidepressant
BunN ClOH
Cl
Fenimide fe·ni·mïd3-Ethyl-2-methyl-2-phenylsuccinimide; C13H15NO2; 60-45-7Tranquilliser
N
Me
OO
Et
H
Fenisorex fe·nï·sö·reks(RS)-cis-7-Fluoro-1-phenylisochroman-3-ylmethylamine; C16H16FNO;34887-52-0Appetite suppressant
OF
H
NH2H
and enantiomer
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2-94Fenitrothion (BAN) fe·nï·trö·thï·on
O,O-Dimethyl O-4-nitro-m-tolyl phosphorothioate; C9H12NO5PS;122-14-5; ̈ NUVAN TOP*Insecticide
P
S
OMe
O
O2N
Me OMe
Fenmetramide fen·me·tra·mïd5-Methyl-6-phenylmorpholin-3-one; C11H13NO2; 5588-29-4Antidepressant
O
NMe OH
**
mixture of 4 stereoisomers
�Fenofibrate fë·no·fi·brätIsopropyl 2-(4-p-chlorobenzoylphenoxy)-2-methylpropionate; C20H21ClO4; 49562-28-9; LIPANTILHypolipidaemic
O COOPr iCl
Me Me
O
Fenoldopam fë·nol·dö·pam6-Chloro-2,3,4,5-tetrahydro-l-p-hydroxyphenyl-lH-3-benzazepine-7,8-diol;C16H16ClNO3; 67227-56-9Fenoldopam Mesilate 67227-57-0; SK&F 82526-JVasodilator
NH
Cl
HO
HO
HO
H
and enantiomer
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2-95Fenoprofen fë·nö·prö·fen
2-(3-Phenoxyphenyl)propionic acid; C15H14O3; 31879-05-7�Fenoprofen Calcium 34957-40-5; FENOPRON; PROGESICAnalgesic; anti-inflammatory
OMeH
COOH
and enantiomer
Fenoterol fe·nö·te·rol1-(3,5-Dihydroxyphenyl)-2-(4-hydroxy-a-methylphenethylamino)ethanol;C17H21NO4; 13392-18-2�Fenoterol Hydrobromide 1944-12-3; BEROTEC; DUOVENT*Beta-adrenoceptor agonist
N
OH
HOH OH
H MeOH
H
* *
mixture of 4 stereoisomers
�Fenpipramide fen·pip·ra·mïd2,2-Diphenyl-4-piperidinobutyramide; C21H26N2O; 77-01-0Spasmolytic
NCONH2
�Fenpiprane fen·pi·prän1-(3,3-Diphenylpropyl)piperidine; C20H25N; 3540-95-2Spasmolytic
N
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2-96Fenprostalene fen·pros·ta·lën
(1) Methyl (±)-7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-(3R)-3-hydroxy-4-phenoxybut-1-enyl]cyclopentyl}hepta-4,5-dienoate; (2) methyl (13E)-(9S*,11R*,15R*)-16-phenoxy-9,11,15-trihydroxytetranorprosta-4,5,13-trienoate;C23H30O6; 69381-94-8; ̈ SYNCHROCEPTLuteolytic (veterinary)
O
H
HOHHHO
CCOOMe
HO
and enantiomer
Fentanyl fen·ta·nïlN-(1-Phenethyl-4-piperidyl)propionanilide; C22H28N2O; 437-38-7; DUROGESIC�Fentanyl Citrate 990-73-8; SUBLIMAZE; ¨HYPNORM*Opioid analgesic
H3CN
NO
�Fenthion fen·thï·onO,O-Dimethyl O-4-methylthio-m-tolyl phosphorothioate; C10H15O3PS2;55-38-9; ̈ TIGUVONInsecticide
P
S
OMe
O
MeS
Me OMe
Fentiazac fen·tï·a·zak4-(4-Chlorophenyl)-2-phenyl-1,3-thiazol-5-ylacetic acid; C17H12ClNO2S; 18046-21-4; Wy 21894; BR 700Analgesic; anti-inflammatory
S
N
COOH
Cl
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2-97Fenticlor fen·ti·klor
2,2¢-Thiobis(4-chlorophenol); C12H8Cl2O2S; 97-24-5; ¨HORSEGUARD*Anti-infective
S
OH OH
ClCl
Fenticonazole fen·ti·ko·na·zôl1-(2,4-Dichlorophenyl)-2-(imidazol-1-yl)ethyl 4-(phenylthio)benzyl ether;C24H20Cl2N2OS; 72479-26-6Fenticonazole Nitrate 73151-29-8; LOMEXINAntifungal
and enantiomer
S
O
Cl Cl
H
NN
Fenvalerate fen·val·er·rät(RS)-a-Cyano-3-phenoxybenzyl (RS)-2-(4-chlorophenyl)-3-methylbutyrate;C25H22ClNO3; 51630-58-1; FLYAWAY; SECTINE
Ectoparasiticide (veterinary)
OO
H CNOCl
Me Me
H
mixture of 4 stereoisomers
Fenyramidol (phenyramidol) fen·i·ra·mi·dol1-Phenyl-2-(2-pyridylamino)ethanol; C13H14N2O; 553-69-5Analgesic
NH OH
N
H
and enantiomer
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2-98Feprazone fe·pra·zön
4-(3-Methylbut-2-enyl)-1,2-diphenylpyrazolidine-3,5-dione; C20H20N2O2; 30748-29-9Analgesic; anti-inflammatory
NN O
OMe
Me
Ferristene fe·ris·tënIron ferrite with carrier particles of mono-sized spheres of cross-linkedpoly(ammonium styrenesulfonate); iron ferrite with carrier particles; 155773-56-1Diagnostic aid
Fertirelin fer·ti·re·lin
<Glu-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro(Et)
C55H76N16O12; 38234-21-8Fertirelin Acetate 106756-71-2; ̈ OVALYSEGonadotrophin releasing hormone
Ferucarbotran (BAN) fe·roo·kar·bö·tranA non-stoichiometric polycrystalline mixture of iron(II) and iron(III) oxides(magnetite Fe3O4 and maghemite-g Fe2O3) in which iron(II) oxide is specified to beless than 5%. It is a colloidal aqueous suspension of superparamagnetic iron oxideparticles coated with carboxydextran. By transmittance electron microscopy(TEM) the iron oxide core has a diameter of 3 to 5 nm. The hydrodynamicdiameter of the coated particles measured by photon correlation spectroscopy(PCS) is 45 to 65 nm. In the colloidal aqueous suspension, the carboxydextrancoat has a thickness of about 25 nm (calculated from PCS measurement).Diagnostic aid
Ferumoxides (BAN) fe·roo·moks·ïdsColloidal particles of non-stoichiometric magnetite; (Fe2O3)m (FeO)n;119683-68-0; AMI-25; ENDOREM
Diagnostic aid
Ferumoxsil (BAN) fe·roo·moks·ilColloidal particles of non-stoichiometric magnetite with a silicone polymer bondedto iron oxide; LUMIREM
Diagnostic aid
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2-99Fetoxilate (fetoxylate) fe·toks·i·lät
2-Phenoxyethyl 1-(3-cyano-3,3-diphenylpropyl)-4-phenylpiperidine-4-carboxylate;C36H36N2O3; 54063-45-5Antidiarrhoeal
N
OO
O
CN
Fexofenadine feks·ö·fen·a·dën(RS)-2-(4-{1-Hydroxy-4-[4-(a-hydroxybenzhydryl)piperidino]butyl}phenyl)-2-methylpropionic acid; C32H39NO4Fexofenadine Hydrochloride 138452-21-8; TELFASTHistamine H1-receptor antagonist; treatment of allergic rhinitis
COOH
Me Me
OHHN
OH
and enantiomer
Filgrastim fil·gras·timRecombinant methionyl human granulocyte colony stimulating factor expressed byE·coli; C845H1339N223O243S9; 121181-53-1; NEUPOGENImmunostimulant
filgrastim has the following amino acid sequence:
MTPLGPASSL PQSFLLKCLE QVRKIQGDGA
ALQEKLCATY KLCHPEELVL LGHSLGIPWA
PLSSCPSQAL QLAGCLSQLH SGLFLYQGLL
QALEGISPEL GPTLDTLQLD VADFATTIWQ
QMEELGMAPA LQPTQGAMPA FASAFQRRAG
GVLVASHLQS FLEVSYRVLR HLAQP
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2-100Finasteride fi·na·ster·rïd
N17-tert-Butyl-3-oxo-4-aza-5a-androst-1-ene-17b-carboxamide; C23H36N2O2; 98319-26-7; PROSCAR5-Alpha reductase inhibitor
HH
Me
HMe
NH
OH
NHButO
H
Fipronil fi·prö·nil(RS)-5-Amino-1-(2,6-dichloro-4-trifluoromethylphenyl)-4-(trifluoro-methylsulfinyl)pyrazole-3-carbonitrile; C12H4Cl2F6N4OS;120068-37-3; ¨ FRONTLINE Insecticide and acaricide (veterinary)
NN CN
H2N S
Cl
Cl
F3C
Oand enantiomer
CF3
Flavoxate fla·voks·ät2-Piperidinoethyl 3-methyl-4-oxo-2-phenyl-4H-chromene-8-carboxylate;C24H25NO4; 15301-69-6�Flavoxate Hydrochloride 3717-88-2; URISPASAnticholinergic
NO O
O
O
Me
Flazalone fla·za·lön4-Fluorophenyl 4-(4-fluorophenyl)-4-hydroxy-1-methyl-3-piperidyl ketone;C19H19F2NO2; 21221-18-1Anti-inflammatory
NMe
OF
HO
F
* *
mixture of 4 stereoisomers
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2-101Flecainide fle·kä·nïd
N-(2-Piperidylmethyl)-2,5-bis(2,2,2-trifluoroethoxy)benzamide; C17H20F6N2O3;54143-55-4�Flecainide Acetate 54143-55-4; TAMBOCORAntiarrhythmic
NH
HNOF3C
O
O
F
H
and enantiomer
Fleroxacin fle·roks·a·sin6,8-Difluoro-1-(2-fluoroethyl)-1,4-dihydro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid; C17H18F3N3O3; 79660-72-3;Ro 23-6240Antibacterial
MeN
N N
F
F
O
COOH
F
Fletazepam fle·tä·ze·pam7-Chloro-5-(2-fluorophenyl)-2,3-dihydro-1-(2,2,2-trifluoroethyl)-1H-1,4-benzodiazepine; C17H13ClF4N2; 34482-99-0; Sch 15698Muscle relaxant
N
N
F
Cl
CF3
Floctafenine flok·ta·fe·nën2,3-Dihydroxypropyl N-(8-trifluoromethyl-4-quinolyl)anthranilate; C20H17F3N2O4;23779-99-9Analgesic
H
N
N
OO OHH OH
F3C
and enantiomer
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2-102Florantyrone flor·ran·tï·rön
4-(Fluoranthen-8-yl)-4-oxobutyric acid; C20H14O3; 519-95-9Choleretic
COOH
O
Florfenicol flor·fe·ni·kol2,2-Dichloro-N-[(aS,bR)-a-(fluoromethyl)-b-hydroxy-4-methanesulfonyl-phenethyl]acetamide; C12H14Cl2FNO4S; 76639-94-6; ̈ NUFLORAntibacterial (veterinary)
Me
O OS
H
Cl
Cl
H OH HN
CH2FO
Flosequinan flö·së·kwi·nan7-Fluoro-1-methyl-3-methylsulfinyl-4-quinolone; C11H10FNO2S;76568-02-0; BTS 49465Antihypertensive
CH3
O
S
O
Me
F N
�Fluanisone floo·a·ni·sön4¢-Fluoro-4-[4-(2-methoxyphenyl)piperazin-l-yl]butyrophenone; C21H25FN2O2;1480-19-9; ̈ HYPNORM*Antipsychotic
N
F
O N
MeO
Flubendazole floo·ben·da·zôlMethyl 5-(4-fluorobenzoyl)-1H-benzimidazol-2-ylcarbamate; C16H12FN3O3; 31430-15-6; ¨FLUBENOLAnthelmintic
N
N
O
F
NHCOOMeH
![Page 281: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/281.jpg)
2-103�Fluclorolone Acetonide floo·klor·ro·lön
9a,11b-Dichloro-6a-fluoro-21-hydroxy-16a,17a-isopropylidenedioxypregna-1,4-diene-3,20-dione; flucloronide (USAN); C24H29Cl2FO5; 3693-39-8Corticosteroid
Me
MeO
O
OHO
Cl
F
O
Me H
Me
Cl H
Flucloxacillin floo·kloks·a·si·lin(6R)-6-[3-(2-Chloro-6-fluorophenyl)-5-methyl-1,2-oxazole-4-carboxamido]penicillanic acid; C19H17ClFN3O5S; 5250-39-5�Flucloxacillin Magnesium 58486-36-5; FLOXAPEN SYRUP�Flucloxacillin Sodium 1847-24-1; FLOXAPEN CAPSULES; FLOXAPEN INJECTION;LADROPEN; MAGNAPEN*; STAFOXILAntibacterial
NO Me
Cl
N
NOO
S
H COOH
Me
Me
H H
F
H
Fluconazole floo·ko·na·zôl2-(2,4-Difluorophenyl)-1,3-bis(1H-1,2,4-triazol-l-yl)propan-2-ol; C13H12F2N6O;86386-73-4; DIFLUCANAntifungal
N
NN
N
N
NF
F
OH
�Flucytosine floo·sï·tö·sën4-Amino-5-fluoropyrimidin-2(1H)-one; 5-fluorocytosine; C4H4FN3O;2022-85-7; ALCOBONAntifungal
N
N O
F
NH2
H
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2-104Fludarabine Phosphate (INNM) floo·da·ra·bën fos·fät
9-b-D-Arabinofuranosyl-2-fluoroadenine 5¢-(dihydrogen phosphate);C10Hl3FN5O7P; 75607-67-9; 21679-14-1 (fludarabine); FLUDARAAntineoplastic
HO
HO
OOP
O
HO
OH
N
N
N
N
NH2
F
Fludrocortisone floo·drö·kor·ti·sön9a-Fluoro-11b,17a,21-trihydroxypregn-4-ene-3,20-dione; C21H29FO5;127-31-1�Fludrocortisone Acetate 514-36-3; FLORINEFCorticosteroid
HF
Me
HMe
O
HO OH
OOH
Fludroxycortide (flurandrenolone) floo·droks·ë·kor·tïd6a-Fluoro-11b,21-dihydroxy-16a,17a-isopropylidenedioxypregn-4-ene-3,20-dione;flurandrenolide (USAN); C24H33FO6; 1524-88-5; HAELAN; HAELAN-C*; HAELAN-XCorticosteroid
HH
Me
HMe
O
F
HO O
O
Me
Me
OHO
Flufenamic Acid floo·fe·na·mikN-(a,a,a-Trifluoro-m-tolyl)anthranilic acid; C14H10F3NO2; 530-78-9Analgesic; anti-inflammatory
N
COOH
f3cH
![Page 283: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/283.jpg)
2-105Flugestone floo·jes·tön
9a-Fluoro-11b,17a-dihydroxypregn-4-ene-3,20-dione; C23H31FO5;337-03-1Flugestone Acetate Fluorogestone acetate (USAN); 2529-45-5; ¨CHRONOGESTProgestogen
HF
Me
HMe
O
HO OH
O CH3
�Flumazenil floo·ma·ze·nilEthyl 8-fluoro-5,6-dihydro-5-methyl-6-oxo-4H-imidazo[1,5-a][1,4]-benzodiazepine-3-carboxylate; C15H14FN3O3; 78755-81-4; ANEXATEBenzodiazepine receptor antagonist
N
N
N
F
O Me
COOEt
Flumedroxone floo·me·droks·ön17a-Hydroxy-6a-trifluoromethylpregn-4-ene-3,20-dione; C22H29F3O3; 15687-21-5Treatment of migraine
HH
Me
HMe
O
OH
O CH3
CF3
Flumequine floo·me·kwën(RS)-9-Fluoro-6,7-dihydro-5-methyl-1-oxo-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid; C14H12FNO3; 42835-25-6; R802Antimicrobial
N Me
O
COOH
F
H
and enantiomer
![Page 284: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/284.jpg)
2-106Flumeridone floo·me·ri·dön
5-Chloro-1-{4-[3-(5-fluoro-2,3-dihydro-2-oxobenzimidazol-1-yl)propyl]-piperidino}-1,3-dihydrobenzimidazol-2-one C22H23ClFN5O2; 75444-64-3; R45486Antiemetic
NH
N
NN
HN
O
O Cl
F
Flumetasone (flumethasone) floo·me·ta·sön6a,9a-Difluoro-11b,17a,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione;C22H28F2O5; 2135-17-3�Flumetasone Pivalate 2002-29-1; ¨ FLUVET; LOCORTEN-VIOFORM*Corticosteroid
Me
OH
OHO
HO
F
O
Me H
Me
F H
�Flumethiazide6-Trifluoromethyl-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide;C8H6F3N3O4S2; 148-56-10
H2N
O OS
O OS
F3C N
NH
Flumethrin (BAN) floo·më·thrina-Cyano-4-fluoro-3-phenoxybenzyl 3-(b,4-dichlorostyryl)-2,2-dimethylcyclopropanecarboxylate; C28H22Cl2FNO3; 69770-45-2; ¨BAYTICOL;¨ BAYVAROL; ¨KILTRIXInsecticide (veterinary)
Flumezapine floo·me·za·pën7-Fluoro-2-methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzo-diazepine; C17H19FN4S; 61325-80-2; LY 120363Antipsychotic
N
N
S
FN
NMe
MeH
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2-107Flunarizine floo·na·ri·zën
trans-1-Cinnamyl-4-(4,4¢-difluorobenzhydryl)piperazine; C26H26F2N2;52468-60-7Flunarizine Hydrochloride 30484-77-6; R 14590Calcium antagonist
N
NF
F
Flunisolide floo·ni·so·lïd6a-Fluoro-11b,21-dihydroxy-16a,17a-isopropylidenedioxypregna-1,4-diene-3,20-dione; C24H31FO6; 3385-03-3; SYNTARISCorticosteroid
HH
Me
HMe
O
F
HO O
O
Me
Me
OHO
�Flunitrazepam floo·nï·trä·ze·pam5-(2-Fluorophenyl)-1,3-dihydro-1-methyl-7-nitro-1,4-benzodiazepin-2-one;C16H12FN3O3; 1622-62-4; ROHYPNOLHypnotic
N
NO2N
OMe
F
Flunixin floo·niks·in2-(a3,a3,a3-Trifluoro-2,3-xylidino)nicotinic acid; C14H11F3N2O2;38677-85-9Flunixin Meglumine 42461-84-7; ¨ FINABIOTIC*; ¨ FINADYNE; ¨OXYCOMPLEX*Analgesic; anti-inflammatory
N
N
COOH
CF3
Me
H
![Page 286: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/286.jpg)
2-108Fluocinolone floo·ö·si·no·lön
6a,9a-Difluoro-11b,16a,17a,21-tetrahydroxypregna-1,4-diene-3,20-dione;C21H26F2O4; 807-38-5�Fluocinolone Acetonide 67-73-2; SYNALAR; SYNALAR C*; SYNALAR N*Corticosteroid
HF
Me
HMe
O
F
HO OH
OH
OHO
�Fluocinonide floo·ö·si·no·nïd6a,9a-Difluoro-11b-hydroxy-16a,17a-isopropylidenedioxy-3,20-dioxopregna-1,4-diene-21-yl acetate; C26H32F2O7; 356-12-7; METOSYNCorticosteroid
HF
Me
HMe
O
F
HO O
O
Me
Me
OAcO
Fluocortin Butyl (INNM) floo·ö·kor·tinButyl 6a-fluoro-11b-hydroxy-16a-methyl-3,20-dioxopregna-1,4-dien-21-oate;C26H35FO5; 33124-50-4Corticosteroid
HH
Me
HMe
O
F
HO
Me
COOBun
Fluocortolone floo·ö·kor·to·lön6a-Fluoro-11b,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione; C22H29FO4;152-97-6�Fluocortolone Hexanoate 303-40-2; ULTRALANUM; ULTRAPROCT*�Fluocortolone Pivalate 29205-06-9; ULTRAPROCT*Corticosteroid
HH
Me
HMe
O
F
HO
Me
OOH
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2-109Fluopromazine see Triflupromazine
Fluorescein (BAN) flûr·re·sën3¢6¢-Dihydroxyspiro[isobenzofuran-1(3H),9¢(9H)-xanthen]-3-one; C20H12O5; 2321-07-5�Fluorescein Sodium 518-47-8; ¨ FLUOROVETS; MINIMS FLUORESCEIN; MINIMSLIGNOCAINE AND FLUORESCEIN*Fluorescein Dilaurate PANCREALAURYL TESTDiagnostic aid
O
OHHO O
O
�Fluorometholone flûr·rö·me·tho·lön9a-Fluoro-11b,17a-dihydroxy-6a-methylpregna-1,4-diene-3,20-dione; C22H29FO4;426-13-1; FML; FML-NEO*Corticosteroid
HF
Me
HMe
O
Me
HO
CH3O
OH
�Fluorouracil flûr·rö·ûr·ra·sil(1) 5-Fluoropyrimidine-2,4(1H,3H)-dione; (2) 5-fluorouracil; C4H3FN2O2; 51-21-8; ACCUSITE*; EFUDIXCytotoxic
NH
N O
O
F
H
Fluoxetine floo·oks·e·tënN-Methyl-3-phenyl-3-(a,a,a-trifluoro-p-tolyloxy)propylamine; C17H18F3NO; 54910-89-3�Fluoxetine Hydrochloride 59333-67-4; PROZACAntidepressant
O
H
NHMe
F3C
and enantiomer
![Page 288: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/288.jpg)
2-110Fluoxymesterone floo·oks·ë·mes·te·rön
9a-Fluoro-11b,17b-dihydroxy-17a-methylandrost-4-en-3-one; C20H29FO3; 76-43-7Anabolic steroid; androgen
HF
Me
HMe
O
HOMe
OH
Fluparoxan floo·pa·roks·an(3aS,9aS)-5-Fluoro-2,3,3a,9a-tetrahydro-1H-[1,4]benzodioxino[2,3-c]pyrrole;C10H10FNO2; 101389-86-0Fluparoxan Hydrochloride 101389-87-1; GR 50360AAntidepressant
O
O
NH
F
Flupentixol (flupenthixol) floo·pen·tiks·ol(Z)-2-{4-[3-(2-Trifluoromethylthioxanthen-9-ylidene)propyl]piperazin-1-yl}ethanol; C23H25F3N2OS; 2709-56-0�Flupentixol Decanoate 30909-51-4; DEPIXOLFlupentixol Hydrochloride 2413-38-9; FLUANXOLAntipsychotic
CF3
SOH
N
N
H
Fluperolone floo·pe·ro·lön(21S)-9a-Fluoro-11b,17a,21-trihydroxy-21-methylpregna-1,4-diene-3,20-dione;C22H29FO6; 3841-11-0Corticosteroid
HF
Me
HMe
O
HO OH
OCH3
H OH
![Page 289: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/289.jpg)
2-111Fluphenazine floo·fe·na·zën
2-{4-[3-(2-Trifluoromethylphenothiazin-10-yl)propyl]piperazin-1-yl}ethanol;C22H26F3N3OS; 69-23-8�Fluphenazine Decanoate 5002-47-1; MODECATE�Fluphenazine Enanthate 2746-81-8; MODITEN ENANTHATE�Fluphenazine Hydrochloride 146-56-5; MODITEN; MOTIPRESS*; MOTIVAL*Antipsychotic
N
S
CF3
N
NOH
Flupirtine floo·per·tënEthyl 2-amino-6-(4-fluorobenzylamino)-3-pyridylcarbamate; C15H17FN4O2; 56995-20-1Flupirtine Maleate 75507-68-5; D 9998Analgesic
NH2
NHCOOEtN
NH
F
Fluprednidene floo·pred·ni·dën9a-Fluoro-11b,17a,21-trihydroxy-16-methylenepregna-1,4-diene-3,20-dione;C22H27FO5; 2193-87-5Corticosteroid
HF
Me
HMe
O
HO
O
OH
OH
CH2
Fluprednisolone floo·pred·ni·so·lön6a-Fluoro-11b,17a,21-trihydroxypregna-1,4-diene-3,20-dione; C21H27FO5; 53-34-9Corticosteroid
HH
Me
HMe
O
HO
O
OH
OH
F
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2-112Fluprofen floo·prö·fen
2-(3¢-Fluorobiphenyl-4-yl)propionic acid; C15H13FO2; 17692-38-5Analgesic; anti-inflammatory
H Me
COOH
F
and enantiomer
Fluproquazone floo·prö·kwa·zön4-(4-Fluorophenyl)-1-isopropyl-7-methylquinazolin-2(1H)-one; C18H17FN2O;40507-23-1; RF 46-790Analgesic; anti-inflammatory
NNPr i
O
F Me
Fluprostenol floo·pros·te·nol(1) (Z)-7-{(1R,2R,3R,5S)-2-[(E)-(3R)-3-Hydroxy-4-(3-tri-fluoromethylphenoxy)-but-1-enyl]-3,5-dihydroxycyclopentyl}hept-5-enoic acid;(2) ent-(5Z,13E)-(9S,11R,15R)-9,11,15-trihydroxy-16-(3-trifluoromethyl-phenoxy)-w-tetranorprosta-5,13-dienoic acid; C23H28F3O6; 40666-16-8Fluprostenol Sodium 55028-71-2Prostanoid; luteolytic
O
H
H OHHHO
COOH
HO
CF3
and enantiomer
Flurandrenolone see Fludroxycortide
Flurazepam flûr·rä·ze·pam7-Chloro-1-(2-diethylaminoethyl)-5-(2-fluorophenyl)-1,3-dihydro-1,4-benzodiazepin-2-one; C21H23ClFN3O; 17617-23-1Flurazepam Dihydrochloride 1172-18-5�Flurazepam Monohydrochloride 36105-20-1; DALMANEHypnotic
N
NCl
O
F
Et2N
![Page 291: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/291.jpg)
2-113�Flurbiprofen flûr·bï·prö·fen
2-(2-Fluorobiphenyl-4-yl)propionic acid; C15H13FO2; 5104-49-4; FROBEN�Flurbiprofen Sodium 56767-76-1; OCUFENAnalgesic; anti-inflammatory
H Me
COOHF
and enantiomer
Flurotyl (flurothyl) flûr·rö·tïlBis(2,2,2-trifluoroethyl) ether; C4H4F6O; 333-36-8Central nervous system stimulant
F3C O CF3
Flusoxolol floo·sok·so·lol(S)-1-{4-[2-(p-Fluorophenethyloxy)ethoxy]phenoxy}-3-isopropylaminopropan-2-ol; C22H30FNO4; 84057-96-5; Ro 31-1411Beta-adrenoceptor antagonist
O NHPr i
OO
H OH
F
�Fluspirilene floo·spi·ri·lën8-[4,4-Bis(4-fluorophenyl)butyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one;C29H31F2N3O; 1841-19-6Antipsychotic
NHN
N O
F
F
Flutamide floo·ta·mïda¢,a¢,a¢-Trifluoro-4¢-nitroisobutyro-m-toluidide; C11H11F3N2O3;13311-84-7; DROGENILAntiandrogen
N
O2N
CF3
O
Me
Me
H
![Page 292: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/292.jpg)
2-114Fluticasone floo·tï·ka·sön
S-Fluoromethyl 6a,9a-difluoro-11b,17a-dihydroxy-16a-methyl-3-oxoandrosta-1,4-diene-17b-carbothioate; C22H27F3O5S; 90566-53-3Fluticasone Propionate 80474-14-2; CUTIVATE; FLIXONASE; FLIXOTIDE;SERETIDE*Corticosteroid
HF
Me
HMe
O
HO
O S
Me
F
OH
F
Flutrimazole floo·trim·a·zôl(RS)-1-(2,4¢-difluorotrityl)imidazole; C22H16F2N2; 119006-77-8; UR-4056Topical antifungal
F
NN
F
and enantiomer
Fluvastatin floo·va·sta·tin(E)-(3RS,5SR)-7-[3-(4-Fluorophenyl)-1-isopropylindol-2-yl]-3,5-dihydroxyhept-6-enoic acid; C24H26FNO4; 93957-54-1Fluvastatin Sodium 93957-55-2; LESCOLHMG-CoA reductase inhibitor
N
F
Pr iCOOH
HO H H OH
and enantiomer
Fluvoxamine floo·voks·a·mën(E)-5-Methoxy-4¢-trifluoromethylvalerophenone O-2-aminoethyloxime;C15H21F3N2O2; 54739-18-3Fluvoxamine Maleate 61718-82-9; FAVERINAntidepressant
OMe
F3C
NO
NH2
![Page 293: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/293.jpg)
2-115�Folic Acid fö·lik
N-[4-(2-Amino-1,4-hydro-4-oxopteridin-6-ylmethylamino)benzoyl]-L-glutamicacid; C19H19N7O6; 59-30-3; LEXPEC; component of many proprietarypreparationsVitamin B component
N
N
N
HN
HN
NCOOH
O
H2N
O H COOH
H
Folinic Acid fö·lin·ik5-Formyltetrahydropteroylglutamic acid; leucovorin; C20H23N7O7�Calcium Folinate leucovorin calcium (USP); 1492-18-8; LEDERFOLIN;REFOLINON
Disodium Folinate SODIOFOLIN
Antidote to folic acid antagonists
N
N N
NN
N COOH
H2N
O CHO
O H COOH
H
H
H
H
![Page 294: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/294.jpg)
2-116Follitropin Alfa fo·li·trö·pin al·fa
Recombinant human follicle-stimulating hormone, alpha-glycoform; it consists oftwo subunits: human gonadotrophin a-subunit protein moiety reduced andhuman follicle-stimulating hormone clone l 15B b-subunit protein moietyreduced; 146479-72-3; GONAL-F
Stimulation of follicle maturation; treatment of infertility
the two subunits have the following amino acid sequences:
NSCELTNITI AIEKEECRFC ISINTTWCAG
YCYTRDLVYK DPARPKIQKT CTFKELVYET
VRVPGCAHHA DSLYTYPVAT QCHCGKCDSD
STDCTVRGLG PSYCSFGEMK E
APDVQDCPEC TLQENPFFSQ PGAPILQCMG
CCFSRAYPTP LRSKKTMLVQ KNVTSESTCC
VAKSYNRVTV MGGFKVENHT ACHCSTCYYH
KS
α-subunit:
β-subunit:
*
* *
*glycosylation sitesa-subunit: C437H682N122O134S13b-subunit: C538H833N145O171S13
Follitropin Beta fo·li·trö·pin bë·taRecombinant human follicle-stimulating hormone, beta-glycoform; it consists oftwo subunits: human gonadotrophin a-subunit protein moiety and human follicle-stimulating hormone b-subunit; the two subunits have the same amino acidsequences and molecular formulae as follitropin alfa; 169108-34-3; PUREGONStimulation of follicle maturation
Fomepizole fö·me·pi·zôl4-Methylpyrazole; C4H6N2; 7554-65-6Alcohol dehydrogenase inhibitor; alcohol antidote
NNH
Me
![Page 295: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/295.jpg)
2-117Fomidacillin fo·mï·da·si·lin
(6R)-6-[D-2-(3,4-Dihydroxyphenyl)-N2-(4-ethyl-2,3-dioxopiperazin-1-ylcarbonyl)glycylamino]-N¢-formylpenicillanic acid; C24H28N6O10S; 98048-07-8Fomidacillin Sodium 86117-56-8; BRL 36650AAntibacterial
HO
N
NOO
S
H COOH
Me
Me
H HHO
NHH
N
N
O
Et
O
O
O
Fomivirsen fö·mi·veer·sendGuoP(S)dCydP(S)dGuoP(S)dThdP(S)dThdP(S)dThdP(S)dGuoP(S)dCydP(S)dThdP(S)dCydP(S)dThdP(S)dThdP(S)dCydP(S)dThdP(S)dThdP(S)dCydP(S)dThdP(S)dThdP(S)dGuoP(S)dCydP(S)dGuo;C204H263N63O114P20S20; 144245-52-3Antiviral CIBA Vision
Fomocaine fö·mö·kän4-[3-(a-Phenoxy-p-tolyl)propyl]morpholine; C20H25NO2; 17692-39-6Local anaesthetic
O
N
O
Formebolone for·me·bo·lön11a,17b-Dihydroxy-17a-methyl-3-oxoandrosta-1,4-diene-2-carbaldehyde;C21H28O4; 2454-11-7Anabolic steroid; androgen
HH
Me
HMe
O
HOMe
OH
OHC
Formestane for·me·stän4-Hydroxyandrost-4-ene-3,17-dione; C19H26O3; 566-48-3; LENTARONAromatase inhibitor; hormonal treatment of advanced breast cancer
HH
Me
HMe
O
O
OH
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2-118Forminitrazole for·mi·nï·tra·zôl
N-(5-Nitro-1,3-thiazol-2-yl)formamide; C4H3N3O3S; 500-08-3Antiprotozoan
N
SO2NHN O
Formocortal for·mö·kor·tal3-(2-Chloroethoxy)-6-formyl-9a-fluoro-11b-hydroxy-16a,17a-isopropylidenedioxy-20-oxopregna-3,5-dien-21-yl acetate; C29H38ClFO8; 2825-60-7Corticosteroid
HF
Me
HMe
CHO
HO O
O
Me
Me
OAcO
Cl
Formoterol (eformoterol) for·mö·te·rol2¢-Hydroxy-5¢-{(RS)-1-hydroxy-2[(RS)-4-methoxy-a-methylphenethylamino]-ethyl}formanilide; C19H24N2O4; 73573-87-2Formoterol Fumarate 43229-80-7; ATOCK; FORADILBeta2-adrenoceptor agonist
N
HO
H OHNO
H MeOMe
H H
and enantiomer
�Fosazepam7-Chloro-1-dimethylphosphinoylmethyl-1,3-dihydro-5-phenyl-1,4-benzodiazepin-2-one; C18H18ClN2O2P; 35322-07-7
N
NCl
OP
OMe
Me
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2-119�Foscarnet Sodium fos·kar·net
Trisodium phosphonatoformate; CNa3O5P; 63585-09-1; FOSCAVIRTreatment of cytomegalovirus (CMV) retinitis
P
O
ONa
COONaNaO
Fosfestrol fos·fës·trol(E)-4,4¢-(1,2-Diethylvinylene)bis(phenyl dihydrogen orthophosphate); C18H22O8P2;522-40-7�Fosfestrol Sodium 23519-26-8; HONVANOestrogen
P
O
OH
OEt
EtO
OH
O
PHO
OH
Fosfluconazole fos·flü·kon·a·zôl1-(2,4-Difluorophenyl)-2-(1H-1,2,4-triazol-1-yl)-1-[(1H-1,2,4-triazol-1-yl)methyl]ethyl dihydrogen phosphate; C13H13F2N6O4P; UK-292,663Antifungal
N N
N
NN
N
O
P OHHO
O
F
F
Fosfomycin fos·fö·mï·sin(1R,2S)-1,2-Epoxypropylphosphonic acid; C3H7O4P; 23155-02-4�Fosfomycin Calcium�Fosfomycin SodiumFosfomycin Trometamol fosfomycin tromethamine (USAN);78964-85-9; MONURILAntibacterial
P(OH)2
O
O
HH
Me
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2-120Fosinopril fo·si·nö·pril
(4S)-4-Cyclohexyl-1-{[(RS)-2-methyl-1-(propionyloxy)propoxy]-(4-phenyl-butyl)phosphinylacetyl}-L-proline; C30H46NO7P; 97825-24-6;Fosinopril Sodium 88889-14-9; STARILAngiotensin-converting enzyme inhibitor
NP
O H COOH
H
O
OPri
OCOEtH
Fosphenytoin fos·fen·ë·tö·in2,5-Dioxo-4,4-diphenylimidazolidin-1-ylmethyl dihydrogen phosphate;C16H15N2O6P; 93390-81-9; CI-982Fosphenytoin Sodium (1:2) 92134-98-0(heptahydrate); PRO-EPANUTIN
Anticonvulsant
O
O
NHN O O
OH
OH
P
Fosquidone fos·kwi·dön(RS)-Benzyl 5,8,13,14-tetrahydro-14-methyl-8,13-dioxobenz[5,6]isoindolo[2,1-b]isoquinolin-9-yl hydrogen orthophosphate; C28H22NO6PFosquidone Sodium 114517-04-3; GR 63178ACytotoxic
P
O
OH
O
N
O
O
O
H Me
and enantiomer
Fotemustine fö·të·mus·tën(±)-Diethyl {1-[3-(2-chloroethyl)-3-nitrosoureido]ethyl}phosphonate;C9H19ClN3O5P; 92118-27-9; S 10036Cytotoxic
P
O
OEtNN
MeHO
NO
Cl OEt
H
and enantiomer
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2-121Framycetin fra·mi·së·tin
An antimicrobial base produced by certain strains of Streptomyces fradiae or S.decaris; 2-deoxy-4-O-(2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl)-5-O-[3-O-(2,6-diamino-2,6-dideoxy-b-L-idopyranosyl)-b-D-ribofuranosyl]-D-streptamine;neomycin B; C23H46N6O13; 119-04-0�Framycetin Sulphate 4146-30-9; ¨CANAURAL*; ¨FRAMOMYCIN; FRAMYCORT*;FRAMYGEN; ¨LEO RED DC*; ¨LEO YELLOW MC*; PROCTOSEDYL*; SOFRADEX*;SOFRAMYCIN*; SOFRA-TULLEAntibacterial
HO
NH2
O
OO
HO
OH
NH2
OH
HO
NH2
O
H2NOH
H2N
CH2NH2OH
Frentizole fren·ti·zôl1-(6-Methoxy-1,3-benzothiazol-2-yl)-3-phenylurea; C15H13N3O2S;26130-02-9Immunoregulant
N
SHN
HN
O
MeO
Frovatriptan frö·va·trip·tan(6R)-5,6,7,8-Tetrahydro-6-methylaminocarbazole-3-carboxamide; C14H17N3O;158747-02-5; SB 209509-AX; VML 251Frovatriptan Succinate 158930-17-7 (monohydrate)5HT1D-Serotonin receptor agonist; treatment of migraine
N
O
H2NNHMe
H
H
Frusemide see Furosemide
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2-122Fulvestrant fúl·vës·trant
7a-[9-(4,4,5,5,5-Pentafluoropentylsulfinyl)nonyl]estra-1,3,5(10)-triene-3,17b-diol; C32H47F5O3S; 129453-61-8; ICI 182,780Anti-oestrogen
SHO
C2F5
Me OH
H
H H
H
H
O
Fumagillin fü·ma·ji·linAn alicyclic antibiotic produced by certain strains of Aspergillus fumigatis; 4-(1,2-epoxy-1,5-dimethylhex-4-enyl)-5-methoxy-1-oxaspiro[2.5]oct-6-yl hydrogen deca-2,4,6,8-tetraenedioate; C26H34O7; 23110-15-8; ¨FUMIDIL B
[ CH=CH] 4HOOC
O
O
MeO
O
O
H CMe2
HMe
Furacrinic Acid fûr·ra·krï·nik6-Methyl-5-(2-ethylacryloyl)benzofuran-2-carboxylic acid; C15H14O4;23580-33-8Diuretic
O COOH
H3C
O
CH2
Me
Furaltadone fûr·ral·ta·dön(RS)-5-Morpholinomethyl-3-(5-nitrofurfurylideneamino)-2-oxazolidone;139-91-3; C13H16N4O6; 139-91-3; ̈ FURASOLAntibacterial
O
N
N
O
NO2 NO
OH
and enantiomer
�Furazolidone fûr·ra·zo·li·dön3-(5-Nitrofurfurylideneamino)-2-oxazolidone; C8H7N3O5; 67-45-8; ¨CORYZIUM;¨ ENTEROLYTE-CF*; FUROXONE; ¨METRIJET*; ¨NEFTIN; ¨NEODIAR*;¨NIFULIDONE; ¨UNIDONEAntibacterial; antifungal; antiprotozoan
N
O
NO2 NO
O
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2-123�Furethidine
Ethyl 4-phenyl-1-[2-(tetrahydrofurfuryloxy)ethyl]piperidine-4-carboxylate;C21H31NO4; 2385-81-10
OO
NCOOEt
Furomine fûr·ro·mën(Z,Z)-2,2,2¢,2¢,5,5,5¢,5¢-Octamethyl-4,4¢-[ethane-1,2-diylbis(iminomethylidyne)]bis(tetrahydrofuran-3-one); C20H32N2O4;142996-66-5Diagnostic agent
HN
O
NH
O OO
Me
MeMe
Me
Me Me MeMe
�Furosemide (frusemide) fûr·rö·se·mïd4-Chloro-N-furfuryl-5-sulfamoylanthranilic acid; (rINN); C12H11ClN2O5S; 54-31-9;ARIDIL*; DIUMIDE-K*; ¨DIURIDE; DRYPTAL; FROOP 40*; FRU-CO*; FRUMIL*;FRUSEMEK*; FRUSENE*; FRUSID; HYDROLED; LASIKAL*; LASILACTONE*; LASIX;LASORIDE*Diuretic
H
O OS
NH2
Cl
HOOC
N
O
Fusafungine fü·sa·fun·jënA depsipeptide antibiotic produced by Fusarium lateritium 437; 1393-87-9;LOCABIOTALAntibiotic
�Fusidic Acid fü·si·dikAn antibiotic produced by a strain of Fusidium; (17Z)-ent-16a-acetoxy-3b,11b-dihydroxy-4b,8b,14a-trimethyl-18-nor-5b,10a-cholesta-17(20),24-dien-21-oicacid; C31H48O6; 6990-06-3�Sodium Fusidate 751-94-0; FUCIBET*; FUCIDIN; FUCITHALMICAntibacterial
Me2CCOOH
HO
Me
HO
Me
Me
OAc
H
H
Me
H
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2-124Fuzlocillin füz·lö·si·lin
6-{[(E)-N-(3-Furfurylideneamino-2-oxoimidazolidin-l-ylcarbonyl)-D-2-(4-hydroxyphenyl)glycyl]amino}penicillanic acid; C25H26N6O8S;66327-51-3; BAY Vk 4999Antibacterial
H
O
HO
N
N
NOO
S
H COOH
Me
Me
H HNH
HO
N
N
HO
Gabapentin ga·ba·pen·tin[1-(Aminomethyl)cyclohexyl]acetic acid; C9H17NO2; 60142-96-3; NEURONTINAnticonvulsant
COOH
NH2
Gadobenic Acid ga·dö·bë·nik[2-(Benzyloxymethyl)-6-(carboxylatomethyl-kO)-3,9-bis(carboxymethyl-kO)-3,6,9-triazaundecanedioato-k3N3,6,9k2O1,11] gadolinium(III); C22H28GdN3O11; 113662-23-0;B19036; Gd-BOPTAParamagnetic contrast medium for magnetic resonance imaging
Gd
HO
O
O
O
ON
O
N
N
O O
OHO O
3 + __
_
Gadodiamide ga·dö·dï·a·mïdAqua[6-carboxylatomethyl-3,9-bis(methylcarbamoylmethyl-k-O)-3,6,9-triazaundecanedioato-k3-N3,N6,N9-k3-O1,O6,O11(3-)gadolinium(III)]; C16H28GdN5O9,xH2O; 122795-43-1; S-041Imaging enhancing agent; paramagnetic contrast agent
O_
HNMeO
MeHN
Gd
O N
_O O
_N N
H2O
O O
O
3+
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2-125Gadopentetic Acid ga·dö·pen·te·tik
{N¢,N¢-Bis(carboxymethyl)-N¢,N¢-[(acetato)iminodiethylene]diglycinato-O,O¢,O¢,N,N¢N¢}gadolinium(3+); C14H20GdN3O10; 80529-93-7Meglumine Gadopentetate 86050-77-3; MAGNEVISTContrast medium
Gd
N
NNCOOH
COO_
COO_
HOOC
_OOC
3+
Gadoteric Acid ga·do·te·rikHydrogen [1,4,7,10-tetrakis(carboxylatomethyl)-1,4,7,10-tetra-azacyclododecane-k4N]gadolinate(1-); C16H25GdN4O8; 72573-82-1Diagnostic aid
NN
NN
Gd
_OOC COO
_
COO_
HOOC
3+
Gadoteridol ga·dö·te·ri·dol[10-(2-Hydroxypropyl-kO)-1,4,7,10-tetra-azacyclododecane-1,4,7-triyltriacetato-O1,O4,O7,N1,N4,N7,N10(3-)]gadolinium(III); C17H29GdN4O7; 120066-54-8;PROHANCE*Imaging enhancement agent
N
O
Gd
N
O
OO
O
O
N
O
N
MeH_
_ _
3+
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2-126Gadoversetamide ga·dö·ver·se·ta·mïd
[N,N-Bis(2-{[(carboxymethyl)[(2-methoxyethyl)-carbamoyl]methyl}aminoethyl)glycinato(3-)]gadolinium; C20H34GdN5O10; 131069-91-5Diagnostic agent
_ _
_OOMe
NH
O
N
O
OMeNH
O
NN
Gd3+
O
O
OO
Galantamine ga·lan·ta·mën(4aS,6R,8aS)-5,6,9,10,11,12-Hexahydro-3-methoxy-11-methyl-4aH-[1]benzofurano[3a,3,2-ef][2]benzazepin-6-ol; C17H21NO3; 357-70-0Treatment of Alzheimer’s disease
O
N
MeO
OHH
Me
H
Galdansetron gal·dan·se·tron(3R)-1,2,3,9-Tetrahydro-9-methyl-3-(5-methyl-1H-imidazol-4-ylmethyl)carbazol-4-one; C18H19N3O; 116684-92-5; GR 81225XGaldansetron Hydrochloride GR 81225C5HT3-Serotonin antagonist; antiemetic; treatment of CNS disorders
NN
NH
O
Me
Me
H
Gallamine ga·la·mën2,2¢,2¢-(Benzene-1,2,3-triyltrioxy)tris(triethylamine); C12H21N3O3;153-76-4�Gallamine Triethiodide 65-29-2; FLAXEDILNeuromuscular blocker
ONEt2
ONEt2
ONEt2
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2-127Gallopamil ga·lo·pa·mil
5-(3,4-Dimethoxyphenethyl-N-methylamino)-2-isopropyl-2-(3,4,5-trimethoxyphenyl)valeronitrile; C28H40N2O5; 16662-47-8Calcium antagonist
NNC Pr i Me
OMe
OMeMeO
OMe
MeO
and enantiomer
Gamolenic Acid ga·mö·lë·nik(Z,Z,Z)-Octadeca-6,9,12-trienoic acid; C18H30O2; 506-26-3; EFAMAST; EPOGAMHypolipidaemic
H
H3C
H
H
H
H
H
COOH
Ganciclovir gan·sï·klö·veer9-{[2-Hydroxy-1-(hydroxymethyl)ethoxy]methyl}guanine; C9H13N5O4; 82410-32-0;CYMEVENEAntiviral
N
N
N
HN
H2N
OOH
OH
O
Ganirelix ga·ni·re·liksN-Acetyl-3-(2-naphthyl)-D-alanyl-p-chloro-D-phenylalanyl-3-(3-pyridyl)-D-alanyl-L-seryl-L-tyrosyl-N6-(N,N¢-diethylcarbamimidoyl)-D-lysyl-L-leucyl-N6-(N,N¢-diethylcarbamimidoyl)-L-lysyl-L-prolyl-D-alaninamide; C80H113ClN18O13; 124904-93-4Ganirelix Acetate 129311-55-3 (1:2) Luteinising-hormone-releasing-hormone antagonist
D–Ala–D–Phe–Ala–Ser–Tyr–D–Lys–Leu–Lys–Pro–Ala–NH2CH3CO
NEtN NHEt
NHEtEtN4-Cl
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2-128Gastric Mucin (BAN) gas·trik mü·sin
High molecular weight glycoprotein precipitated by ethanol (60%) after pepsin/hydrochloric acid digestion of hogs’ stomach linings; SALIVA ORTHANATreatment of xerostomia and Sjogren’s syndrome
Gavestinel ga·ves·ti·nel4,6-Dichloro-3-[2-(phenylcarbamoyl)vinyl]indole-2-carboxylic acid;C18H12Cl2N2O3; 153436-22-7; GV 150526XNMDA channel glycine receptor antagonist; treatment of stroke
Cl
Cl N
N
COOH
O
H
H
(E-isomer)
Gefarnate je·fa·nätA mixture of stereoisomers of 3,7-dimethylocta-2,6-dienyl 5,9,13-trimethyltetradeca-4,8,12-trienoate; geranyl farnesylacetate; C27H44O2;51-77-4Treatment of peptic ulcer
Me O Me
MeMeMeOMeMe
mixture of isomers
Gemcitabine gem·sï·ta·bën(1) 4-Amino-1-(2-deoxy-2,2-difluoro-b-D-ribofuranosyl)pyrimidin-2(1H)-one; (2)2¢-deoxy-2¢,2¢-difluorocytidine; C9H11F2N3O4; 95058-81-4Gemcitabine Hydrochloride 122111-03-9; GEMZARAntineoplastic
F
HOO
FOH
N
N
NH2
O
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2-129�Gemeprost je·me·prost
(1) Methyl (E)-7-{(1R,2R,3R)-3-hydroxy-2-[(E)-(3R)-3-hydroxy-4,4-dimethyloct-1-enyl]-5-oxocyclopentyl}hept-2-enoate;(2) methyl (2E,13E)-(11R,15R)-11,15-dihydroxy-16,16-dimethyl-9-oxoprosta-2,13-dienoate; C23H38O5; 64318-79-2Inducer of uterine muscle contraction
H
H OHHHO
OCOOMe
CH3Me Me
�Gemfibrozil jem·fi·brö·zil2,2-Dimethyl-5-(2,5-xylyloxy)valeric acid; C15H22O3; 25812-30-0; LOPIDHypolipidaemic
OCOOH
Me
Me
Me Me
Gentamicin jen·ta·mï·sinA mixture of aminoglycoside antibiotics produced by Micromonospora purpurea; 1403-66-3�Gentamicin Sulphate 1405-41-0; CIDOMYCIN; GARAMYCIN; GENTICIN;GENTISONE HC*; ¨MINIMS GENTAMICIN; ¨PANGRAMAntibacterial
NH2NH2
OH
O
O
H2N
OOH
NHMe
Me
OHO
R1R3
R2
� ��������� ��
��
��
�
� �� � �
�
� � ��
�
��
� � ��
�
��
� � ��
�
Gestodene jes·tö·dën13b-Ethyl-17b-hydroxy-18,19-dinor-17a-pregna-4,15-dien-20-yn-3-one; C21H26O2;60282-87-3; FEMODENE*; MINULET*; TRIADENE*; TRI-MINULET*Progestogen
H H
Et
H H
O
OHCH
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2-130Gestonorone (gestronol) jes·ton·or·rön
17a-Hydroxy-19-norpregn-4-ene-3,20-dione; C20H28O2Gestonorone Hexanoate 1253-28-7; DEPOSTATProgestogen
H
Me
H
O
OHH
CH3O
H
Gestrinone je·stri·nön13b-Ethyl-17a-ethynyl-17b-hydroxygona-4,9,11-trien-3-one; C21H24O2; 16320-04-0;DIMETRIOSEInhibitor of pituitary gonadotrophin secretion
H
Me
H
O
OHH
CH3O
H
Glaspimod gla·spi·mod(2S,7S)-N 2,N 2¢-[2,7-bis(L-5-oxoprolyl-L-glutamyl-L-aspartylamino)octanedioyl]di-L-lysine; C48H74N12O22; 134143-28-5;SK&F 107647Immunomodulator
HN
HN
HN
HN OHN
HO
O
O O O O
NH2
COOH
COOH
COOH
COOH
NH
NH
NH
NH
OH
HN
O
O
O O O O
NH2
Glatiramer Acetate gla·ti·ra·mer a·se·tätAcetate salt of synthetic polypeptides prepared by chemically reacting the protectedand activated derivatives of four amino acids: L-glutamic acid (L-Glu), L-alanine (L-Ala), L-tyrosine (L-Tyr) and L-lysine (L-Lys) in a specific ratio. The molar fraction ofeach amino acid residue ranges as follows:L-Glu 0.129-0.153, L-Ala 0.329-0.462, L-Tyr 0.086-0.100 and L-Lys 0.300-0.374.The average molecular weight is between 4700 and 11,000 daltons with at least68% of the material within the range of 2,500 to 28,000 daltons;28704-27-0; COP-1Immunomodulator; treatment of multiple sclerosis
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2-131Gleptoferron glep·tö·fe·ron
Macromolecular complex of iron(III) hydroxide and dextranglucoheptonic acid;57680-55-4; ¨GLEPTOSIL*Iron preparation
�Glibenclamide glï·ben·kla·mïd1-{4-[2-(5-Chloro-2-methoxybenzamido)ethyl]benzenesulfonyl}-3-cyclohexylurea;glyburide (USAN); C23H28ClN3O5S; 10238-21-8; CALABREN; DAONIL; EUGLUCON;SEMI DAONILHypoglycaemic
O
NH
N
SOOO
Cl
OMe
NH
H
Glibornuride glï·bor·nûr·rïd1-[(2S,3R)-2-Hydroxyborn-3-yl]-3-tosylurea; C18H26N2O4S; 26944-48-9Hypoglycaemic
MeMeH
OH
N N
O
Me
SOO
MeH H
�Gliclazide glï·kla·zïd1-(3-Azabicyclo[3.3.0]oct-3-yl)-3-p-tolylsulfonylurea; C15H21N3O3S;21187-98-4; DIAMICRONHypoglycaemic
N N
O
Me
SOO
N
H H
Glimepiride gli·me·pi·rïdtrans-1-{4-[2-(3-Ethyl-4-methyl-2-oxo-3-pyrroline-1-carboxamido)ethyl]-phenylsulfonyl}-3-(4-methylcyclohexyl)urea; C24H34N4O5S; 93479-97-1; AMARYLHypoglycaemic
HN
O
N
OEt
Me
SOO
NN
OMe
H H
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2-132�Glipizide glï·pi·zïd
1-Cyclohexyl-3-{4-[2-(5-methylpyrazine-2-carboxamido)ethyl]-phenylsulfonyl}urea; C21H27N5O4S; 29064-61-9; GLIBENESE; MINODIABHypoglycaemic
HO
NH
N
SOO
Me
O
NHN
N
�Gliquidone glï·kwi·dön1-Cyclohexyl-3-{p-[2-(3,4-dihydro-7-methoxy-4,4-dimethyl-1,3-dioxo-2(1H)-isoquinolyl)ethyl]phenylsulfonyl}urea; C27H33N3O6S;33342-05-1; GLURENORMHypoglycaemic
Me MeO
O
MeON
O OS
NH
NH
O
Glisoxepide glï·soks·ë·pïd1-Azepan-1-yl-3-{4-[2-(5-methyl-1,2-oxazole-3-carboxamido)ethyl]-phenylsulfonyl}urea; C20H27N5O5S; 25046-79-1Hypoglycaemic
O
NH
NH
N
O OS
Me
O
NH
O N
Gloxazone gloks·a·zön3-Ethoxy-2-oxobutyraldehyde bis(thiosemicarbazone); C8H16N6OS2;2507-91-7Antiprotozoan
H
OH3CNNHCNH2
NNHCNH2
MeH
S
S
and enantiomer
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2-133�Glucagon gloo·ka·gon
A peptide hormone produced by the a-cells of the Islets of Langerhans;C153H225N43O49S; 16941-32-5; GLUCAGEN
Antihypoglycaemic; gastrointestinal motility inhibitor
For labelling purposes, when glucagon is produced by recombinant processes, thename carries in parentheses an approved code, in lower case letters, indicative ofthe method of production. The following code is approved and others may beissued on request:
(rys) produced by fermentation using Saccharomyces cerevisiae containing arecombinant plasmid
glucagon has the following aminoacid sequence:
His Ser Gln Gly Thr Phe Thr Ser
Asp Tyr Ser Lys Tyr Leu Asp Ser
Arg Arg Ala Gln Asp Phe Val Gln
Trp Leu Met Asn Thr
Glucalox (glycalox) gloo·ka·loksA polymerised complex of glycerol and aluminium hydroxide; glucalox (rINN);12182-48-8Antacid
Glucuronamide gloo·kûr·ro·na·mïdb-D-Glucopyranuronamide; b-D-glucuronamide; C6H11NO6; 3574-23-0Metabolic aid
O OH
OH
OH
CONH2
HO
�Glutethimide gloo·te·thi·mïd(RS)-2-Ethyl-2-phenylglutarimide; C13H15NO2; 77-21-4Hypnotic
N
Et
OOH
and enantiomer
Glycalox see Glucalox
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2-134Glycobiarsol (bismuth glycollylarsanilate) glï·kö·bï·ar·sol
[4-Glycolamidophenylarsonato(1-)]oxobismuth; C8H9AsBiNO6; 116-49-4Antiprotozoan
OBiON
AsO
HO
O
OH
H
Glycopyrronium Bromide glï·kö·pi·rö·në·um3-(a-Cyclopentylmandeloyloxy)-1,1-dimethylpyrrolidinium bromide; glycopyrrolate(USAN); C19H28BrNO3; 596-51-0; ROBINULAnticholinergic#
O
NMe2
OH
OBr
+ _
and enantiomer
Glymidine Sodium (glymidine) glï·mi·dënSodium salt of N-[5-(2-methoxyethoxy)pyrimidin-2-yl]benzenesulfonamide;C13H15N3O4S; 3459-20-9Hypoglycaemic
NH
N
NO
OMe
SOO
�Glysobuzole (isobuzole)N-(5-Isobutyl-1,3,4-thiadiazol-2-yl)-4-methoxybenzenesulfonamide; C13H17N3O3S2;3567-08-6
NN
SNH
Me
Me
SOO
MeO
�Gonadorelin go·na·dö·rë·linLuteinising hormone-and follicle stimulating hormone-releasing factor;C55H75N17O13; 33515-09-2; ¨FERTAGYL; FERTIRAL; RELEFACT LH-RH/TRH*Gonadotrophin-releasing hormone
5-oxoPro-His-Trp-Ser-Tyr-Gly-Leu-Arg-Pro-Gly-NH2
Gonadotrophin see Chorionic Gonadotrophin and Serum Gonadotrophin
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2-135Goserelin gö·se·re·lin
C59H84N18O14; 65807-02-5Goserelin Acetate ZOLADEXGonadorelin analogue
5-oxoPro-His-Trp-Ser-Tyr-Gly-D-Ser(tert-Bu)-Leu-Arg-Pro-NH·NH·CONH2
�Gramicidin gra·mi·sï·dinAn antimicrobial cyclic polypeptide produced by the growth of Bacillus brevisDubos·; ADCORTYL WITH GRANEODIN*; GRANEODIN *; NEOSPORIN*; SOFRADEX*;SOFRAMYCIN*; TRI-ADCORTYL*; TRI-ADCORTYL OTIC*Antibacterial
Granisetron gra·ni·se·tron1-Methyl-N-[(3r)-9-methyl-9-azabicyclo[3.3.1]non-3-yl]-1H-indazole-3-carboxamide; C18H24N4OGranisetron Hydrochloride 107007-99-8; KYTRIL5HT3-Serotonin receptor antagonist
NMe
HN
O
NN
Me
Grepafloxacin gre·pa·floks·a·sin(RS)-1-Cyclopropyl-6-fluoro-1,4-dihydro-5-methyl-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid; C19H22FN3O3; 119914-60-2Grepafloxacin Hydrochloride 161967-81-3; REAXAR
Antibacterial
HN
N
F
NMe
Me O
COOH
H
and enantiomer
�Griseofulvin gri·zë·ö·ful·vin(1¢S,6¢R)-7-Chloro-2¢,4,6-trimethoxy-6¢-methyl-3H-spiro[benzo[b]furan-2,1¢-cyclohex[2]ene]-3,4¢-dione; C17H17ClO6; 126-07-8; ¨DUFULVIN; ¨EQUIFULVIN;FULCIN;¨GRISOL V; GRISOVIN; ¨NOROFULVINAntibacterial
O
Cl
MeO
OMe O
O
MeO
Me
�Growth Hormone (BAN)Extract of human pituitaries containing predominantly growth hormone·
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2-136�Guaifenesin (guaiphenesin) gwï·fen·ë·sin
3-(2-Methoxyphenoxy)propane-1,2-diol; C10H14O4; 93-14-1; present in manyantitussive preparationsExpectorant
OMe
O OHH OH
and enantiomer
Guamecycline gwa·më·sï·klënN 2-(4-Guanidinoformimidoylpiperazin-1-ylmethyl)tetracycline; C29H38N8O8; 16545-11-2Antibacterial
OH O HO O
OH
NMe2HH
MeHO
OH
N N
O
N
NH
NH
H2N
NH
H
�Guanacline1-[2-(1,2,3,6-Tetrahydro-4-methyl-1-pyridyl)ethyl]guanidine; C9H18N4; 1463-28-1
NN NH2
MeNH
H
Guanethidine gwa·ne·thi·dën1-[2-(Perhydroazocin-1-yl)ethyl]guanidine; C10H22N4; 55-65-2�Guanethidine Monosulphate 645-43-2; GANDA*; ISMELINAdrenergic neurone blocker
HN NH2
NH
N
Guanfacine gwan·fa·sënN-Amidino-2-(2,6-dichlorophenyl)acetamide; C9H9Cl2N3O; 29110-47-2Guanfacine Hydrochloride 29110-48-3; BS 100-141Alpha2-adrenoceptor agonist
HN NH2
NH
Cl
ClO
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2-137Guanoclor gwa·nö·klor
1-[2-(2,6-Dichlorophenoxy)ethylamino]guanidine; C9H12Cl2N4O;5001-32-1Guanoclor Sulphate 551-48-4Adrenergic neurone blocker
O
Cl
ClNH
NH2
HN
NH
Guanoxan gwa·noks·an(RS)-1-(2,3-Dihydro-1,4-benzodioxin-2-ylmethyl)guanidine; C10H13N3O2;2165-19-7Guanoxan Sulphate 5714-04-5Adrenergic neurone blocker
HN NH2
NH
O
OH
and enantiomer
Hachimycin ha·chi·mï·sinA mixture of heptaenes with antifungal activity produced by Streptomyceshachijoensis; trichomycin; 1394-02-1Antifungal
Halazepam ha·lä·ze·pam7-Chloro-1,3-dihydro-5-phenyl-1-(2,2,2-trifluoroethyl)-1,4-benzodiazepin-2-one;C17H12ClF3N2O; 23092-17-3; Sch 12041Anxiolytic
N
NCl
OF3C
Halcinonide hal·si·no·nïd21-Chloro-9a-fluoro-11b-hydroxy-16a,17a-isopropylidenedioxypregn-4-ene-3,20-dione; C24H32ClFO5; 3093-35-4; HALCIDERMCorticosteroid
HF
Me
HMe
O
OCl
O
O
Me
Me
HO
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2-138Haletazole (halethazole) ha·le·ta·zôl
2-[4-(5-Chloro-1,3-benzothiazol-2-yl)phenoxy]ethyldiethylamine; C19H21ClN2OS;15599-36-7Antifungal
N
S
ONEt2
Cl
Halofantrine hä·lö·fan·trën(RS)-3-Dibutylamino-l-(1,3-dichloro-6-trifluoromethyl-9-phenanthryl)propan-1-ol;C26H30Cl2F3NO; 69756-53-2Halofantrine Hydrochloride HALFANAntimalarial
NBun2
H OHF3C
Cl Cl
and enantiomer
Halofenate ha·lo·fe·nät2-Acetamidoethyl 4-chlorophenyl(a,a,a-trifluoro-m-tolyloxy)acetate;C19H17ClF3NO4; 26718-25-2Hypolipidaemic
OO
O
NHAc
Cl
H
F3C
and enantiomer
Halofuginone hä·lö·fü·ji·nön(RS)-trans-7-Bromo-6-chloro-3-[3-(3-hydroxy-2-piperidyl)acetonyl]quinazolin-4(3H)-one; C16H17BrClN3O3; 55837-20-2Halofuginone Hydrobromide 64924-67-0; ̈ STENEROLAntiprotozoan
N
NNH
Br
Cl
O
HOO
and enantiomer
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2-139Halopenium Chloride hä·lö·pë·në·um
(4-Bromobenzyl)[3-(4-chloro-2-isopropyl-5-methylphenoxy)propyl]-dimethylammonium chloride; C22H30BrCl2NO; 7008-13-1Anti-infective
O N
Cl
Me
Pr i
BrMe Me
Cl
+_
�Haloperidol hä·lö·pe·ri·dol4-[4-(4-Chlorophenyl)-4-hydroxypiperidino]-4¢-fluorobutyrophenone;C21H23ClFNO2; 52-86-8; DOZIC; HALDOL; SERENACEHaloperidol Decanoate 74050-97-8; HALDOL DECANOATEAntipsychotic
N
Cl
OH
O
F
Halopyramine see Chloropyramine
�Halothane hä·lö·thän1-Bromo-1-chloro-2,2,2-trifluoroethane; C2HBrClF3; 151-67-7; FLUOTHANEAnaesthetic
CF3
Cl Br
�Haloxon ha·loks·onBis(2-chloroethyl) 3-chloro-4-methylcoumarin-7-yl phosphate; C14H14Cl3O6P; 321-55-1; ¨EQUILOX; ¨MULTIWURMA; ¨RUBY HORSE WORMERAnthelmintic
P
O
O
O
Cl
OO
Cl
Me
OCl
�Halquinol (BAN) hal·kwi·nolA mixture of chlorinated products of quinolin-8-ol containing about 65 per cent of5,7-dichloroquinolin-8-ol; 8067-69-4;Anti-infective
N
OH
Cl
Cl N
OH
Cl
N
OH
Cl
+ +
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2-140�Hedaquinium Chloride
2,2¢-Hexadecamethylenedi(2-isoquinolinium) dichloride; C34H46Cl2N2;4310-89-8
N 16 NCH2 2Cl
+ +_
Heparin (BAN) he·pa·rinAn anionic polysaccharide of mammalian origin, with irregular sequence, consistingprincipally of alternating iduronate and glucosamine residues, most of which aresulfated; 9005-49-6�Heparin Calcium 3727-0-89-6; CALCIPARINE; MONOPARIN CA; UNIPARIN CA�Heparin Sodium 9041-08-1; CANUSAL; HEPSAL; MONOPARIN; MULTIPARIN;¨TENSOLVET; UNIPARINAnticoagulant�Heptabarb (heptabarbitone)5-(Cyclohept-1-enyl)-5-ethylbarbituric acid; heptabarb (rINN); C13H18N2O3; 509-86-4Hypnotic
NH
N OO
O
Et
H
Heptaminol hep·ta·mi·nol6-Amino-2-methylheptan-2-ol; C8H19NO; 372-66-7Vasodilator
H3C Me
H NH2 HO Me
and enantiomer
Hetacillin he·ta·si·lin(6R)-6-[(4R)-2,2-Dimethyl-5-oxo-4-phenylimidazolidin-1-yl]penicillanic acid;C19H23N3O4S; 3511-16-8Antibacterial
NO
S
H COOH
Me
Me
H H
NHN
OH
Me Me
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2-141Hetaflur he·ta·flûr
Hexadecylamine hydrofluoride; C16H36FN; 3151-59-5; 143-27-1 (base);GA 242Prophylaxis of dental caries
H3C CH2 CH2NH314
+F
_
Hetastarch (BAN) he·ta·starchA starch consisting of more than 90% of amylopectin and partially etherified withhydroxyethyl groups; hydroxyethyl-starch; 9005-27-0; HESPANPlasma volume expander
Heteronium Bromide he·ter·rö·në·um(RS)-1,1-Dimethyl-3-(a-2-thienylmandeloyloxy)pyrrolidinium bromide;C18H22BrNO3S; 7247-57-6Anticholinergic
NMe2O
O
S
HO
Br+ _
and enantiomer
�Hexachlorophene (hexachlorophane) heks·a·klor·rö·fën2,2¢-Methylenebis(3,4,6-trichlorophenol); C13H6Cl6O2; 70-30-4; ANACAL*;DERMALEX*; STER-ZAC POWDER; TORBETOL*Anti-infective
OH
Cl
Cl
ClCl
Cl
Cl
OH
Hexadimethrine Bromide heks·a·dï·me·thrënPoly(4,4-dimethyl-4-ammoniodecyldimethylammonium dibromide);[C13H30Br2N2]n; 9011-04-5Heparin antagonist
N NMe2Me2
+ +2Br
_n
Hexamethonium Bromide heks·a·me·thö·në·umN,N-Hexamethylenebis(trimethylammonium) dibromide; C12H30Br2N2;55-97-0Ganglion blocker
NMe3Me3N+
+2Br
_
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2-142Hexamethonium Iodide (INNM)
N,N-Hexamethylenebis(trimethylammonium) di-iodide; C12H30I2N2;870-62-2Ganglion blocker
NMe3Me3N+
+2I
_
Hexamethonium Tartrate (INNM)N,N-Hexamethylenebis(trimethylammonium) di(hydrogen tartrate);C12H30N2,2(C4H6O6); 2079-78-9Ganglion blocker
NMe3Me3N
++
HOOCCOO
_OHH
H OH 2
Hexamidine heks·a·mi·dën4,4´-(Hexane-1,6-diyldioxy)dibenzamidamide; C20H26N4O2; 3811-75-4�Hexamidine Isetionate 659-40-5Antiprotozoal
OO
NH2
HN
NH2
NH
Hexamine Hippurate see Methenamine
Hexaprofen heks·a·prö·fen2-(4-Cyclohexylphenyl)propionic acid; C15H20O2; 24645-20-3Analgesic; anti-inflammatory
H Me
COOH
and enantiomer
Hexapropymate heks·a·prö·pi·mät1-(Prop-2-ynyl)cyclohexyl carbamate; C10H15NO2; 358-52-1Hypnotic
OH2N
O
CH
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2-143Hexazole (BAN) heks·a·zôl
4-Cyclohexyl-3-ethyl-1,2,4-triazole; C10H17N3; 4671-03-8Central nervous system stimulant
N
N
N Et
Hexcarbacholine (carbolonium bromide) heks·kar·ba·kö·lënN,N¢-Hexamethylenebis(2-carbamoyloxyethyltrimethylammonium) dibromide;C18H40Br2N4O4; 306-41-2Neuromuscular blocker
H
HN O
O
NMe3Me3N
O
NO 2Br
++ _
Hexetidine heks·e·ti·dën1,3-Bis(2-ethylhexyl)perhydro-5-methylpyrimidin-5-ylamine; C21H45N3;141-94-6; ¨HEXOCIL; ORALDENEAntiseptic
N NH EtHEt
CH3H3C
Me NH2
mixture of isomers
�Hexobarbital (hexobarbitone) heks·ö·bar·bi·tal5-(Cyclohex-1-enyl)-1,5-dimethylbarbituric acid; C12H16N2O3; 56-29-1Hexobarbital Sodium 50-09-9Hypnotic
NH
NO O
O
Me
Me
Hexobendine heks·ö·ben·dënEthylenebis[(methyl)iminopropane-3,1-diyl] bis(3,4,5-trimethoxybenzoate);C30H44N2O10; 54-03-5Vasodilator
MeO
MeO
OMe
ON
N O
O Me
Me
O
OMe
OMe
OMe
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2-144Hexocyclium Metilsufate heks·ö·sï·klë·um
4-(b-Cyclohexyl-b-hydroxyphenethyl)-1,1-dimethylpiperazinium methylsulfate;C21H36N2O5S; 115-63-9Anticholinergic
N
NMe2HO
H3COSO3
+ _
and enantiomer
�HexoprenalineN,N¢-Hexamethylenebis[4-(2-amino-1-hydroxyethyl)pyrocatechol]; C22H32N2O6;3215-70-1
N
HO
OH
H OH
NOHH
OH
OH
H
H
mixture of isomers
�Hexylresorcinol heks·ïl·re·sor·si·nol4-Hexylbenzene-1,3-diol; C12H18O2; 136-77-6Anthelmintic
CH3
HO
OH
Homatropine ho·ma·trö·pën(1R,3r,5S)-Tropan-3-yl (RS)-mandelate; C16H21NO3; 87-00-3�Homatropine Hydrobromide 51-56-9; MINIMS HOMATROPINE�Homatropine Methylbromide 80-49-9Anticholinergic
NMe
O
O
H OH
and enantiomer
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2-145�Homidium Bromide ho·mi·dë·um
3,8-Diamino-5-ethyl-6-phenylphenanthridinium bromide; C21H20BrN3; 1239-45-8Antiprotozoan
NH2N
NH2
EtBr+ _
Homochlorcyclizine hö·mö·klor·sï·kli·zën1-(4-Chlorobenzhydryl)perhydro-4-methyl-1,4-diazepine; C19H23ClN2;848-53-3Histamine H1-receptor antagonist
and enantiomer
NH
Cl
N Me
Homprenorphine hom·pre·nor·fën(1) (2R)-2-[(-)-(5R,6R,7R,14R)-9a-Cyclopropylmethyl-4,5-epoxy-3,6-dimethoxy-6,14-ethenomorphinan-7-yl]butan-2-ol; (2) 17-cyclopropylmethyl-7,8-dihydro-7-[(1R)-1-hydroxy-1-methylpropyl]-3,6-di-O-methyl-6,14-etheno-17-normorphine;C28H37NO4; 16549-56-7Opioid analgesic
N
O
MeO
HMe
HO
MeO
CH3
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2-146�Human Insulin
A protein having the normal structure of the natural antidiabetic principle pro-duced by the human pancreas. When produced by synthesis, semi-synthesis orother artificial means, the name, for labelling purposes, carries in parentheses anapproved code in lower case letters indicative of the method of production;C257H383N65O77S6; 11061-68-0; for trade names see Biphasic Insulin Injection; BiphasicIsophane Insulin Injection; Insulin Injection; Insulin Zinc Suspension; Insulin Zinc Suspension(Amorphous); Insulin Zinc Suspension (Crystalline)and Isophane Insulin InjectionHypoglycaemicThe following codes are approved and others will be made available as the needarises:(emp) produced by the enzymatic modification of insulin obtained from the
pancreas of the pig
(crb) produced by the chemical combination of the A and B chains of the protein,each chain having been obtained from bacteria genetically-modified byrecombinant DNA technology
(prb) produced from proinsulin obtained from bacteria genetically-modified byrecombinant DNA technology.
human insulin has the following amino acid sequence:
Gly_Ile_Val_Glu_Gln_Cys_Cys_Thr_
Ser_Ile_Cys_Ser_Leu_Tyr_Gln_Leu_
Glu_Asn_Tyr_Cys_Asn
Phe_Val_Asn_Gln_His_Leu_Cys_Gly_
Ser_His_Leu_Val_Glu_Ala_Leu_Tyr_
Leu_Val_Cys_Gly_Glu_Arg_Gly_Phe_
Phe_Tyr_Thr_Pro_Lys_Thr
Chain B
Chain A
Human Menopausal Gonadotrophins (BAN)Purified extract of human post-menopausal urine containing follicle-stimulatinghormone (FSH) and luteinising hormone (LH); the relative in-vivo activity isdesignated as a ratio
The following forms of Human Menopausal Gonadotrophins are recognised:Human Menopausal Gonadotrophins (FSH:LH, 3:1) HUMEGON FD;NORMEGON
Human Menopausal Gonadotrophins (FSH:LH, 2:1) PERGOGREEN*NB Human Menopausal Gonadotrophins (FSH:LH, 1:1) is known asmenotrophin·Treatment of male and female infertilitysee also Follitropin Alfa, Follitropin Beta and Menotrophin
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2-147Hyalosidase hï·a·lö·si·däz
An enzyme catalysing the random hydrolysis of 1® 4-linkages between 2-acetamido-2-deoxy-b-D-glucose and b-D-glucuronate residues in hyaluronic acid;hyaluronoglucosaminidase (EC 3.2.1.35); GL EnzymeEnzyme
Hyaluronic Acid (BAN) hï·a·lûr·ro·nik(1® 3)-O-(2-Acetamido-2-deoxy-b-D-glucopyranosyl)-(1® 4)-O-b-D-gluco-pyranosiduronan; 9004-61-9Sodium Hyaluronate 9004-32-7; ¨HYALOVET; ¨HYLARTIL; ¨REMOBILASETreatment of synovitis (veterinary)
�Hyaluronidase hï·a·lûr·ro·ni·däzEnzymes that depolymerise hyaluronic acid; 9001-54-1; HYALASE; LASONIL*
Hydralazine hï·dra·la·zënPhthalazin-1-ylhydrazine; C8H8N4; 86-54-4�Hydralazine Hydrochloride 304-20-1; APRESOLINEVasodilator
N
N
NHNH2
�Hydrargaphen hï·drar·ja·fenBis[phenylmercury(II)] 3,3¢-methylenedinaphthalene-2-sulfonate); C33H24Hg2O6S2;14235-86-0Antibacterial
SO2OHg
HgOSO2
CH2
�Hydrochlorothiazide hï·drö·klor·rö·thï·a·zïd6-Chloro-3,4-dihydro-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide;C7H8ClN3O4S2; 58-93-5; HYDROSALURIC; ¨VETIDREX; component in manyproprietary preparationsDiuretic
H2N
O OS
O OS
N
NH
ClH
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2-148Hydrocodone hï·drö·kö·dön
(1) (-)-(5R)-4,5-Epoxy-3-methoxy-9a-methylmorphinan-6-one;(2) 6-deoxy-3-O-methyl-6-oxomorphine; C18H21NO3; 125-29-1Antitussive
NMe
O
MeO
H
O
�Hydrocortisone hï·drö·kor·ti·sön11b,17a,21-Trihydroxypregn-4-ene-3,20-dione; C21H30O5; 50-23-7; DIODERM;EFCORTELAN; EURAX-HYDROCORTISONE;¨ HYDROCORTISTAB; HYDROCORTISYL;HYDROCORTONE; component in many other proprietary preparations�Hydrocortisone Acetate 50-03-3; COLIFOAM; CORLAN; ¨CORTOCAPS;HYDROCORTISTAB; MILDISON; component in many other proprietarypreparationsHydrocortisone Butyrate 13609-67-1; LOCOID; LOCOID C*; LOCOID CRELO�Hydrocortisone Hydrogen Succinate 2203-97-6�Hydrocortisone Sodium Phosphate� 6000-74-4; EFCORTESOL�Hydrocortisone Sodium Succinate 125-04-2; EFCORTOLAN SOLUBLE;¨NEOBIOTIC DRY COW*; SOLU-CORTEFCorticosteroid
HH
Me
HMe
O
HO
O
OH
OH
�Hydroflumethiazide hï·drö·floo·me·thï·a·zïd3,4-Dihydro-6-trifluoromethyl-2H-1,2,4-benzothiadiazine-7-sulfonamide1,1-dioxide; C8H8F3N3O4S2; 135-09-1; ALDACTIDE*; HYDRENOX; SPIRO-CO*Diuretic
H2N
O OS
O OS
N
NH
F3CH
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2-149Hydromorphinol hï·drö·mor·fi·nol
(1) (5R,6S)-4,5-Epoxy-9a-methylmorphinan-3,6,14-triol; (2) 7,8-dihydro-14-hydroxymorphine; C17H21NO4; 2183-56-4Opioid analgesic
NMe
O
HO
HOOH
Hydromorphone hï·drö·mor·fön(1) (-)-(5R)-4,5-Epoxy-3-hydroxy-9a-methylmorphinan-6-one; (2) 6-deoxy-7,8-dihydro-6-oxomorphine; C17H19NO3; 466-99-9Hydromorphone Hydrochloride 71-68-1; PALLADONE
Opioid analgesic
NMe
O
HO
H
O
�Hydrotalcite hï·drö·tal·sïtAluminium magnesium carbonate hydroxide hydrate; Mg6Al2(OH)6CO3·4H2O;12304-65-3; ALTACITE; ALTACITE PLUS*Antacid
Hydroxamethocaine see Hydroxytetracaine
�Hydroxocobalamin hï·droks·ö·kö·ba·la·minCoa-[a-(5,6-Dimethylbenzimidazol-1-yl)]-Cob-hydroxocobamide;C62H89CoN13O15P; 13422-51-0; COBALIN-H; LIPFLAVONOID*; LIPOTRIAD*;NEO-CYTAMENVitamin B12 analogue
H2N
OMe
H2N
O
H
Me
OO
HO
H
OHHHP
O
O_
ONH H Me
O O
HNH2
Me
Me
MeMe
O
H2N
Me
O
NH2 O
NH2
Me
N
N
Co
N
N
N
N Me
Me
H
H
H
H
+
OH
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2-150Hydroxyamfetamine (hydroxyamphetamine) hï·droks·ë·am·fe·ta·mën
4-(2-Aminopropyl)phenol; C9H13NO; 103-86-6Sympathomimetic
HO
CH3
H NH2
and enantiomer
Hydroxyapatite (BAN) hï·droks·ë·a·pa·tïtDecacalcium dihydroxide hexakis(orthophosphate); 3Ca3(PO4)2·Ca(OH)2;Ca5(OH)(PO4)3; 1306-06-5; present in OSSOPAN as microcrystalline hydroxyapatiteCalcium salt
�Hydroxycarbamide (hydroxyurea) hï·droks·ë·kar·ba·mïdHydroxyurea; CH4N2O2; 127-07-1; HYDREACytotoxic
H2N NOH
O
H
Hydroxychloroquine hï·droks·ë·klor·rö·kwën(RS)-2-[4-(7-Chloro-4-quinolylamino)pentyl(ethyl)amino]ethanol; C18H26ClN3O;118-42-3�Hydroxychloroquine Sulphate 747-36-4; PLAQUENILAntimalarial
NCl
HN
H MeN CH3
OH
and enantiomer
Hydroxydione Sodium Succinate hï·droks·ë·dï·önSodium 3,20-dioxo-5a-pregnan-21-yl succinate; C25H35NaO6; 53-10-1Anaesthetic
HH
Me
HMe
OH
OO COONa
O
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2-151Hydroxypethidine hï·droks·ë·pe·thi·dën
Ethyl 4-(3-hydroxyphenyl)-1-methylpiperidine-4-carboxylate; C15H21NO3; 468-56-4Opioid analgesic
NMe
COOEt
OH
Hydroxyprocaine hï·droks·ë·prö·kän2-Diethylaminoethyl 4-aminosalicylate; C13H20N2O3; 487-53-6Local anaesthetic
ONEt2
O
OHH2N
Hydroxyprogesterone hï·droks·ë·prö·jes·te·rön17a-Hydroxypregn-4-ene-3,20-dione; C21H30O3; 68-96-2�Hydroxyprogesterone Caproate (hydroxyprogesterone hexanoate) 630-56-8;PROLUTON DEPOTProgestogen
HH
Me
HMe
O
O CH3
OH
Hydroxystilbamidine hï·droks·ë·stil·ba·mi·dën2-Hydroxystilbene-4,4¢-dicarboxamidine; C16H16N4O; 495-99-8Antiprotozoan
CH CHNH2
NHHN
H2NHO
�Hydroxytetracaine (hydroxamethocaine)2-Dimethylaminoethyl 4-butylaminosalicylate; C15H24N2O3; 490-98-2
OH
ONMe2
BunHN
O
Hydroxytoluic Acid hï·droks·ë·to·lü·ik2-Hydroxy-m-toluic acid; C8H8O3; 83-40-9Analgesic
COOH
OH
Me
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2-152Hydroxyurea see Hydroxycarbamide
Hydroxyzine hï·droks·i·zën(RS)-2-{2-[4-(p-Chloro-a-phenylbenzyl)piperazin-1-yl]ethoxy}ethanol;C21H27ClN2O2; 68-88-2Hydroxyzine Hydrochloride 2192-20-3; ATARAX; UCERAXHistamine H1-receptor antagonist
N
NH
N
Et
HO
Cl
H Me
and enantiomer
Hyoscine (BAN) hï·ö·sën(1S,3s,5R,6R,7S,8s)-6,7-Epoxy-3-[(S)-tropoyloxy]tropane; C17H21NO4;51-34-3 SCOPODERM; SCOPODEX�Hyoscine Hydrobromide Scopolamine hydrobromide (USAN);114-49-8; ¨RENACHEK*�Hyoscine Butylbromide 149-64-4; BUSCOPANHyoscine Methobromide methscopolamine bromide (USAN);155-41-9Hyoscine Methonitrate 6106-46-3Anticholinergic
NMe
O
O
O
OH
H
�Hyoscyamine (BAN) hï·ö·sï·a·mën(1R,3r,5S)-Tropan-3-yl (S)-tropate; C17H23NO3; 101-31-5��Hyoscyamine Sulphate 620-61-1Anticholinergic
NMe
O
O
OH
H
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2-153�Hypromellose hï·prö·me·lös
A mixed ether of cellulose containing, by weight, 27 to 30% of methoxyl groupsand 4 to 7·5% of hydroxypropyl groups; 8063-82-9; ILUBE*; ISOPTO PREPARA-TIONS*; MAXIDREX*; MAXITROL*; OCUCOAT; TEARS NATURALE*�Hypromellose PhthalateTreatment of tear deficiency
Ibafloxacin ï·ba·floks·a·sin(RS)-9-Fluoro-6,7-dihydro-5,8-dimethyl-1-oxo-1H,5H-pyrido[3,2,1-ij]quinoline-2-carboxylic acid; C15H14FNO3;91618-36-9; S-25930; R-835Antibacterial
N
F
O
COOH
Me
Me
Ibandronic Acid ï·ban·dro·nik a·sid1-Hydroxy-3-[methyl(pentyl)amino)propane-1,1-diylbis(phosphonic acid);C9H22NO7P2; 114084-78-5; BM 21·0955Sodium IbandronateAnti-osteoclastic; treatment of inhibition of bone resorption
H3CN OH
Me
P
P
O
O
OHHO
OHHO
Ibopamine ï·bö·pa·mën4-(2-Methylaminoethyl)-o-phenylene di-isobutyrate; C17H25NO4;66195-31-1; SK&F 100168Dopamine receptor agonist; inotrope
OCOPr i
OCOPr iMeHN
Ibufenac ï·bú·fe·nak(4-Isobutylphenyl)acetic acid; C12H16O2; 1553-60-2Analgesic; anti-inflammatory
COOH
Me
Me
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2-154�Ibuprofen ï·bü·prö·fen
(RS)-2-(4-Isobutylphenyl)propionic acid; C13H18O2; 15687-27-1; ADVIL; ANAFEN;APSIFEN; ARTHROFEN; BRUFEN; CODAFEN*; CUPROFEN; DEEP RELIEF; EBUFAC;FENBID; GALPROFEN; HEDEX IBUPROFEN; IBUFAC; IBULEVE; IBUSPRAY; INFLAM;INOVEN; ISISFEN; JUNIFEN; LEMSIP*; LIBROFEM; LIDIFEN; LIFEN; MIGRAFEN;MOTRIN; NUROFEN; PACIFENE; PHOR PAIN; PROFLEX; RELCOFEN; SOLPAFLEX;TAYLOR'SAnalgesic; anti-inflammatory
COOH
Me
Me
H Me
and enantiomer
Ibutilide ï·bü·ti·lïd(RS)-4¢-{4-[Ethyl(heptyl)amino]-1-hydroxybutyl}methanesulfonanilide;C20H36N2O3S; 122647-31-8; U-70226EIbutilide Fumarate 122647-32-9Antiarrhythmic
and enantiomer
Me
O OS
N
Et
NOHH
[CH2]6 CH3
H
�Ichthammol (BAN) ik·tha·molAmmonium salts of the sulfonic acids of an oily substance prepared from a bitumi-nous schist or shale, together with ammonium sulfate and water;8029-68-3; ICHTHOPASTE*; ICTHABAND*Anti-infective
Icodextrin ï·kö·deks·trin(1® 4)-a-D-Glucan having more than 85% of its molecules with molecular weightsbetween 1640 and 45,000 with a weight-average molecular weight of approximately20,000; [C6H10O5]n; 9004-53-9; ICODIALPeritoneal dialysis fluid excipient
Icometasone Enbutate (icomethasone enbutate) ï·kö·me·ta·sön en·bü·tät9a-Chloro-11b-hydroxy-16a-methyl-3,20-dioxopregna-1,4-diene-17,21-diyl 17-butyrate 21-acetate; C28H37ClO7; 103466-73-5; CL09Corticosteroid
HCl
Me
HMe
O
O
OHO
MeCH3
OAc
O
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2-155Idarubicin ï·da·roo·bi·sin
(7S,9S)-9-Acetyl-7-(3-amino-2,3,6-trideoxy-a-L-lyxo-hexopyranosyloxy)-7,8,9,10-tetrahydro-6,9,11-trihydroxynaphthacene-5,12-dione; C26H27NO9; 58957-92-9Idarubicin Hydrochloride 57852-57-0; ZAVEDOSCytotoxic
O
O
OH
OH
CH3
O
H
HO
O
NH2
HOMe
O
Idazoxan ï·da·zoks·an(RS)-2-(2,3-Dihydro-1,4-benzodioxin-2-yl)-2-imidazoline; C11H12N2O2;79944-58-4Idazoxan Hydrochloride 79944-56-2; RX 781094Alpha2-adrenoceptor antagonist
N
N
O
OH
H
and enantiomer
Idoxifene ï·doks·i·fën(E)-1-{2-[4-(1-p-Iodophenyl-2-phenylbut-1-enyl)phenoxy]ethyl}pyrrolidine;C28H30INO; 116057-75-1; CB 7432Oestrogen-receptor antagonist
ON
I
H3C
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2-156�Idoxuridine ï·doks·ûr·ri·dën
5-Iodo-1-(2-deoxy-b-D-erythro-pentofuranosylpyrimidine-2,4(1H,3H)-dione;C9H11N2O5; 54-42-2; HERPID*; IDURIDIN*; VIRUDOX*Antiviral
HO
OHO
N
HN
O
O
I
Ifosfamide ï·fos·fa·mïd3-(2-Chloroethyl)-2-(2-chloroethylamino)-1,3,2-oxazaphosphorinane 2-oxide;C7H15Cl2N2O2P; 3778-73-2; MITOXANACytotoxic
N
PO N
Cl
Cl
O H
Iloperidone ï·lö·pe·ri·dön1-(4-{3-{4-(6-Fluoro-1,2-benzoxazol-3-yl)piperidino]propoxy}-3-methoxyphenyl)ethanone; C24H27FN2O4; 133454-47-4Antipsychotic
NO
N O
OMe
F
CH3
O
Iloprost ï·lö·prost(E)-5-{(3aS,4R,5R,6aS)-5-Hydroxy-4-[(E)-(3S,4RS)-3-hydroxy-4-methyloct-1-en-6-ynyl]perhydropentalen-2-ylidene}pentanoic acid; C22H32O4; 73873-87-7Peripheral and cerebral vasodilator; anticoagulant
HOHHHO
HOOC H
H Me CH3H
H
*
and epimer at C*
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2-157Imciromab Pentetate (INNM) im·sï·rö·mab pen·te·tät
An IgG2a antibody derived from the cell line R11D10 and directed to the heavychain of human cardiac myosin; 126132-83-0; MYOSCINTCardiac imaging agent
Imidapril i·mï·da·pril(S)-3-{N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl}-1-methyl-2-oxoimidazolidine-4-carboxylic acid; C20H27N3O6; 89371-37-9Imidapril Hydrochloride 89396-94-1; TA-6366Angiotensin-converting enzyme inhibitor
NO
MeH
COOHH
N
NH
EtOOCO
Me
H
Imidaprilat i·mï·da·pri·lat(4S)-3-{(2S)-2-[(1S)-1-Carboxy-3-phenylpropylamino]propionyl}-1-methyl-2-oxoimidazolidine-4-carboxylic acid; C18H23N3O6; 89371-44-8; 6366AAngiotensin-converting enzyme inhibitor; antihypertensive
NO
MeH
COOHH
N
NH
OMe
HOOC
H
Imidocarb i·mï·dö·karb1,3-Bis[3-(2-imidazolin-2-yl)phenyl]urea; C19H20N6O; 27885-92-3Imidocarb Dipropionate ¨ IMIZOLAntiprotozoan
N
HNHN
HN
O
NH
N
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2-158Imiglucerase i·mi·gloo·se·räs
Recombinant, human-derived, macrophage-targeted b-glucocerebrosidase(r-GCR); a monomeric glycoprotein of 497 amino acids glycosylated at asparagineresidues 19, 59, 146 and 270; C2532H3843N671O711S16; 154248-97-2
For labelling purposes, the following three-letter code, to indicate the method ofproduction, is approved:
(rch) produced from genetically engineered chinese hamster ovary cellsimiglucerase has the following amino acid sequence:
ARPCIPKSFG YSSVVCVCNA TYCDSFDPPT
FPALGTFSRY ESTRSGRRME LSMGPIQANH
TGTGLLLTLQ PEQKFQKVKG FGGAMTDAAA
LNILALSPPA QNLLLKSYFS EEGIGYNIIR
VPMASCDFSI RTYTYADTPD DFQLHNFSLP
EEDTKLKIPL IHRALQLAQR PVSLLASPWT
SPTWLKTNGA VNGKGSLKGQ PGDIYHQTWA
RYFVKFLDAY AEHKLQFWAV TAENEPSAGL
LSGYPFQCLG FTPEHQRDFI ARDLGPTLAN
STHHNVRLLM LDDQRLLLPH WAKVVLTDPE
AAKYVHGIAV HWYLDFLAPA KATLGETHRL
FPNTMLFASE ACVGSKFWEQ SVRLGSWDRG
MQYSHSIITN LLYHVVGWTD WNLALNPEGG
PNWVRNFVDS PIIVDITKDT FYKQPMFYHL
GHFSKFIPEG SQRVGLVASQ KNDLDAVALM
HPDGSAVVVV LNRSSKDVPP TIKDPAVGFL
ETISPGYSIH TYLWHRQ
*
*
*
*
*glycosylation site
Enzyme (b-glucocerebrosidase); treatment of Gaucher’s disease
Imipenem i·mi·pe·nem(5R,6S)-6-[(R)-1-Hydroxyethyl]-3-[2-(iminomethylamino)ethylthio]-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid; C12H17N3O4S; 64221-86-9;PRIMAXIN*Antibacterial
NO
HH
HO
HMe
COOH
SN NHH
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2-159Imipramine i·mi·pra·mën
3-(10,11-Dihydro-5H-dibenz[b,f]azepin-5-yl)propyldimethylamine; C19H24N2; 50-49-7�Imipramine Hydrochloride 113-52-0; TOFRANILAntidepressant
N
NMe2
Imiquimod i·mi·kwi·mod1-Isobutyl-1H-imidazo[4,5-c]quinolin-4-ylamine; C14H16N4; 99011-02-6Treatment of external genital and perianal warts
N
N
N NH2
Bu i
Imolamine i·mo·la·mënDiethyl[2-(5-imino-3-phenyl-1,2,4-oxadiazolin-4-yl)ethyl]amine; C14H20N4O; 318-23-0Vasodilator
N
N
O
NEt2
NH
Impromidine im·prö·mi·dën1-(3-Imidazol-4-ylpropyl)-3-[2-(5-methylimidazol-4-ylmethylthio)ethyl]guanidine;C14H23N7S; 55273-05-7Impromidine Hydrochloride 65573-02-6; SK&F 92676-A3Histamine H2-receptor agonist
N
N N NS
NH NNH
MeH H
H
Indalpine in·dal·pën3-[2-(4-Piperidyl)ethyl]indole; C15H20N2; 63758-79-2Antidepressant
N
NH
H
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2-160�Indapamide in·da·pa·mïd
(RS)-4-Chloro-N-(2-methylindolin-1-yl)-3-sulfamoylbenzamide; C16H16ClN3O3S;26807-65-8; NATRILIX; NATARMIDDiuretic
NNH
O
SO2NH2
ClMe
H
and enantiomer
Indenolol in·dë·no·lol1H-Inden-4(or 7)-yloxy-3-isopropylaminopropan-2-ol; C15H21NO2; 60607-68-3;Sch 28316ZBeta-adrenoceptor antagonist
NHPr iOH OH
and enantiomer
Indinavir in·din·a·veer(2R,4S)-2-Benzyl-5-[(2S)-2-tert-butylcarbamoyl)-4-(3-pyridylmethyl)piperazin-1-yl]-4-hydroxy-N-[(1S,2R)-2-hydroxyindan-1-yl]pentanamide; C36H47N5O4; 150378-17-9; CRIXIVANIndinavir Sulphate 157810-81-6; L735,524, MK-639HIV-protease inhibitor; antiviral
N
N
NHN
O
H
CONHBut
H
OHHOHH
H
Indolidan in·do·li·dan3,3-Dimethyl-5-(1,4,5,6-tetrahydro-6-oxopyridazin-3-yl)indolin-2-one;C14H15N3O2; 100643-96-7; Ly 195115Cardiac stimulant
N
NHN
O
O
Me
Me
H
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2-161�Indometacin (indomethacin) in·dö·me·ta·sin
1-(4-Chlorobenzoyl)-5-methoxy-2-methylindol-3-ylacetic acid; C19H16ClNO4; 53-86-1; ARTRACIN; FLEXIN; IMBRILON; INDOCID; INDOLAR; INDOMAX; INDOMOD;MAXIMET; RHEUMACINAnalgesic; anti-inflammatory
N
Cl
COOH
MeO
OMe
Indoprofen in·dö·prö·fen(RS)-p-(1-Oxoisoindolin-2-yl)hydratropic acid; C17H15NO3; 31842-01-0Analgesic; anti-inflammatory
N
MeH
COOHO
and enantiomer
Indoramin in·dor·ra·minN-[1-(2H-Indol-3-ylethyl)-4-piperidyl]benzamide; C22H25N3O; 26844-12-2�Indoramin Hydrochloride 33124-53-7; BARATOL; DORALESEAlpha-adrenoceptor antagonist
HN
N
HN
O
Infliximab in·fliks·i·mabImmunoglobulin G (human-mouse monoclonal cA2 heavy chain anti-humantumour necrosis factor), disulfide with human mouse monoclonal cA2 light chain,dimer; 170277-31-3Immunomodulator
Inosine Pranobex (INNM) ï·nö·sën pra·nö·beksInosine—2-hydroxypropyldimethylammonium 4-acetamidobenzoate (1:3)C10H12N4O5·C14H22N2O4; 36703-88-5; IMUNOVIRAntiviral
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2-162�Inositol Nicotinate i·nö·si·tol
myo-Inositol hexanicotinate; inositol niacinate (USAN); C42H30N6O12;6556-11-2; HEXOPALVasodilator
R
RR
R
R
RR =
N
COO
�Inproquone2,5-Di(aziridin-1-yl)-3,6-dipropoxy-1,4-benzoquinone; C16H22N2O4;436-40-8
N
N
O
O
OPrn
PrnO
Insulin (BAN) see Biphasic Insulin Injection, Human Insulin, Insulin Zinc Suspension, InsulinZinc Suspension (Amorphous), Insulin Zinc Suspension (Crystalline), Isophane Insulin andNeutral Insulin Injection
Insulin Aspart in·sü·lin as·part[28B-L-aspartic acid]insulin (human); C256H381N65O79S6; 116094-23-6Hypoglycaemicinsulin aspart has the following amino acid sequence:
Gly–Ile–Val–Glu–Gln–Cys–Cys–Thr–
Ser–Ile–Cys–Ser–Leu–Tyr–Gln–Leu–
Glu–Asn–Tyr–Cys–Asn
Phe–Val–Asn–Gln–His–Leu–Cys–Gly–
Ser–His–Leu–Val–Glu–Ala–Leu–Tyr–
Leu–Val–Cys–Gly–Glu–Arg–Gly–Phe–
Phe–Tyr–Thr–Asp–Lys–Thr
Chain A
Chain B
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2-163Insulin Detemir in·sü·lin de·te·meer
Des-30B-L-threonine-29B-(N6-myristoyl-L-lysine human insulin; C267H402N64O 76S 6;169148-63-4Hypoglycaemic Novo Nordisk
Gly–Ile–Val–Glu–Gln–Cys–Cys–Thr–
Ser–Ile–Cys–Ser–Leu–Tyr–Gln–Leu–
Glu–Asn–Tyr–Cys–Asn
Phe–Val–Asn–Gln–His–Leu–Cys–Gly–
Ser–His–Leu–Val–Glu–Ala–Leu–Tyr–
Leu–Val–Cys–Gly–Glu–Arg–Gly–Phe–
Phe–Tyr–Thr–Pro–Lys
Chain A
Chain B
H3C O
N 6
Insulin Glargine in·sü·lin glar·jën21A-Glycine-30Ba-L-arginine-30Bb-L-arginineinsulin (human); C267H404N72O78S6;160337-95-1Hypoglycaemic
insulin glargine has the following amino acid sequence:
Gly_Ile_Val_Glu_Gln_Cys_Cys_Thr_
Ser_Ile_Cys_Ser_Leu_Tyr_Gln_Leu_
Glu_Asn_Tyr_Cys_Gly
Phe_Val_Asn_Gln_His_Leu_Cys_Gly_
Ser_His_Leu_Val_Glu_Ala_Leu_Tyr_
Leu_Val_Cys_Gly_Glu_Arg_Gly_Phe_
Phe_Tyr_Thr_Pro_Lys_Thr_Arg_Arg
Chain B
Chain A
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2-164�Insulin Injection (BAN)
A neutral, sterile solution of insulin or of human insulin; neutral insulin; neutralinsulin injection; soluble insulin; HUMAN ACTRAPID; HUMAN VELOSULIN;HUMULIN S; HYPURIN NEUTRAL; ¨ INSUVET; PORK VELOSULIN; PUR-IN NEUTRAL;VELOSULIN
Insulin Lispro in·sü·lin lis·prö28B-L-Lysine-29B-L-proline human insulin ; C257H383N65O77S6;133107-64-9; HUMALOGHypoglycaemic
insulin lispro has the following amino acid sequence:
Gly_Ile_Val_Glu_Gln_Cys_Cys_Thr_
Ser_Ile_Cys_Ser_Leu_Tyr_Gln_Leu_
Glu_Asn_Tyr_Cys_Asn
Phe_Val_Asn_Gln_His_Leu_Cys_Gly_
Ser_His_Leu_Val_Glu_Ala_Leu_Tyr_
Leu_Val_Cys_Gly_Glu_Arg_Gly_Phe_
Tyr_Thr_Lys_Pro_Thr
Chain B
Chain A
�Insulin Zinc Suspension (Mixed)A sterile, neutral suspension of beef or pork insulin (or a mixture of beef and porkinsulin) or of human insulin complexed with a suitable zinc salt; HUMANMONOTARD; HUMAN LENTE; HYPURIN LENTELENTARD MCHypoglycaemic
�Insulin Zinc Suspension (Amorphous)A sterile, neutral suspension of beef or pork insulin (or a mixture of beef and porkinsulin) complexed with a suitable zinc salt; the insulin is in a form insoluble inwater; SEMITARD MCHypoglycaemic
�Insulin Zinc Suspension (Crystalline)A sterile, neutral suspension of beef or pork insulin (or a mixture of beef and porkinsulin) complexed with a suitable zinc salt; the insulin is in the form of crystalsinsoluble in water; HUMAN ULTRATARD; HUMULIN ZNHypoglycaemic
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2-165Interferon (BAN) in·ter·feer·ron
Proteins formed by the interaction of animal cells with viruses, capable of confer-ring on animal cells resistance to virus infection; 9008-11-1�Interferon AlfaA family of secreted proteins, known previously as leucocyte interferon orlymphoblastoid interferon, that is produced according to the information coded bymultiple interferon alfa genes.
Sub-species of the human alfa gene produce protein variants designated by thehyphenated addition of a number, eg interferon alfa-2, or in the case of a mixture ofproteins, by an alphanumeric designation eg n1, n2 etc. The numbers conformwith the recommendations of the Interferon Nomenclature Committee; thealphanumeric designations will be assigned by the World Health Organization onrequest. In the case of interferon alfa-2 the number is qualified according to theamino-acid residues X and Y at positions 23 and 34 in the chain by an arbitraryletter.
For labelling purposes, the name carries, in parenthesis, an approved code, inlower case letters, indicative of the method of production. The following codes areapproved, and others will be made available on request:(rbe) produced from bacteria (E. coli) genetically modified by recombinant DNA
technology.(lns) produced from cultured lymphoblasts from the Namalwa cell line that have
been stimulated by a Sendai virus.(bls) produced from leucocytes from human blood that have been stimulated by
a Sendai virus·interferon alfa has the following amino acid sequence:
MCDLPQTHSL GSRRTLMLLA QMRXISLFSC
LKDRYDFGFP QEEFGNQFQK AETIPVLHEM
IQQIFNLFST KDSSAAWDET LLDKFYTELY
QQLNDLEACV IQGVGVTETP LMKEDSILAV
RKYFQRITLY LKEKKYSPCA WEVVRAEIMR
SFSLSTNLQE SLRSKE
The following examples of interferon alfa are recognised:
Residue atposition
Designation 23 34 Code Trade mark CAS No·
Alfa-2a Lys (K) His (H) (rbe) ROFERON 76543-85-9Alfa-2b Arg (R) His (H) (rbe) INTRONA 99210-65-8
VIRAFERONAlfa-2c Arg (R) Arg (R) (rbe) BEROFORAlfa-n1 ¾ ¾ (lns) WELLFERONAlfa-n2 ¾ ¾ (bls) EXOVIR HZ
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2-166Interferon Alfacon-1 in·ter·feer·ron al·fa·kon
N-L-Methionyl-22-L-arginine-76-L-alanine-78-L-aspartic acid-79-L-glutamic acid-86-L-tyrosine-90-L-tyrosine-156-L-threonine-157-L-asparagine-158-L-leucineinterferon a1 (human lymphoblast reduced); C870H1366N236O259S9; 118390-30-0Antiviral
interferon alfacon-1 has the following amino acid sequence:
MCDLPQTHSL GNRRALILLA QMRRISPFSC
LKDRHDFGFP QEEFDGNQFQ KAQAISVLHE
MIQQTFNLFS TKDSSAAWDE SLLEKFYTEL
YQQLNDLEAC VIQEVGVEET PLMNVDSILA
VKKYFQRITL YLTEKKYSPC AWEVVRAEIM
RSFSLSTNLQ ERLRRKE
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2-167Interferon Beta
A secreted protein, known previously as fibroblast interferon, that is producedaccording to the information coded by multiple interferon alfa genes·
Sub-species of the human beta gene produce protein variants designated by thehyphenated addition of a number, eg interferon beta-1. The numbers conform withthe recommendations of the Interferon NomenclatureCommittee; the alphanumeric designations will be assigned by the World HealthOrganization on request. In the case of interferon beta-1 the number is qualified byan arbitary letter according to the amino-acid residues at positions 1 and 17 in thechain and to whether or not glycosylation is present·
For labelling purposes, the name carries, in parenthesis, an approved code, inlower case letters, indicative of the method of production. The following codes areapproved, and others will be made available on request:(rch) produced from genetically engineered Chinese hamster ovary cells
interferon beta has the following amino acid sequence:
MSYNLLGFLQ RSSNFQCQKL LWQLNGRLEY
CLKDRMNFDI PEEIKQLQQF QKEDAALTIY
EMLQNIFAIF RQDSSSTGWN ETIVENLLAN
VYHQINHLKT VLEEKLEKED FTRGKLMSS
HLKRYYGRIL HYLKAKEYSH CAWTIVRVEI
LRNFYFINRL TGYLR
*
*Glycosylation site
Interferon Beta-1a Interferon Beta-1b
Residue at position 1 Met (M) —
Residue at position 17 Cys (C) Ser (S)Glycosylation yes (position 80) no
Molecular formula(a-a sequence only) C908H1406N246O252S7 C903H1397N246O252S5
CAS Registry No· 145258-61-3 90598-63-3Trade names AVONEX; REBIF BENESERON; BETAFERON
Manufacturing code rch rbeAction and use Immunomodulator; Immunomodulator;
antineoplastic; antiviral antiviral; treatmenttreatment of multiple sclerosis of multiple sclerosis
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2-168Interferon Gamma
A secreted protein, known previously as immune interferon, that is producedaccording to the information coded by a species of interferon gene. As withinterferon alfa, protein variants of interferon gamma have been produced and aredifferentiated by alphanumeric suffixes. The qualifying terms are designatedaccording to the nature of the termini X and Y at positions 1 and 139 in the chain(see below).
For labelling purposes, the name carries, in parenthesis , an approved code, inlower case letters, indicative of the method of production (see under Interferonalfa).
interferon gamma has the following amino acid sequence:
X-QDPYVKEAEN LKKYFNAGHS DVADNGTLFL
GILKNWKEES DRKIMQSQIV SFYFKLFKNF
KDDQSIQKSV ETIKEDMNVK FFNSNKKKRD
DFEKLTNYSV TDLNVQRKAI HELIQVMAEL
SPAAKTGKRK RSQMLFRGR-Y
The following examples of interferon gamma are recognised.
Gamma-1a Gamma-1b*
Terminus X: Cys-Tyr-Cys (CTC) Met (M)Terminus Y: Arg-Ala-Ser-Gln (RASQ) -OH
Manufacturing Code: rbe
Trade Mark: IMMUNERON IMMUKIN
CAS Reg. No: 98059-18-8 98059-61-1
*formerly interferon gamma-2a
�Inulin (BAN)Polysaccharide granules obtained from the tubers of Dahlia variabelis, Helvanthustuberosus and other genera of the family CompositaeDiagnostic aid used in the determination of renal function
Iobenzamic Acid ï·ö·ben·za·mikN-(3-Amino-2,4,6-tri-iodobenzoyl)-N-phenyl-b-alanine; C16H13N2O3;3115-05-7; OSBILContrast medium
NCOOH
I
O
NH2
I
I
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2-169Iobitridol ï·ö·bi·tri·dol
N,N¢-Bis(2,3-dihydroxypropyl)-5-(3-hydroxy-2-hydroxymethylpropionamido)-2,4,6-tri-iodo-N,N¢-dimethylisophthalamide; C20H28I3N3O9; 136949-58-1Contrast medium
HN
NHO
HO
O Me
OH
N
Me
OHO
OH
OH
O
I
I
I
mixture of stereoisomers
*
*
Iocarmic Acid ï·ö·kar·mik5,5¢-(Adipoyldiamino)bis(2,4,6-tri-iodo-N-methylisophthalamic acid);C24H20I6N4O8; 10397-75-8Meglumine Iocarmate 54605-45-7; DIMER XContrast medium
H
COOH
I
I
I
MeHN
O
N
O
[CH2]4
COOH
I
I
I
NHMe
O
N
O
H
Iocetamic Acid ï·ö·se·ta·mik(RS)-2-[N-(3-Amino-2,4,6-tri-iodophenyl)acetamidomethyl]propionic acid;C12H13I3N2O3; 16034-77-8Contrast medium
I
I
I
NCOOH
MeHH2N
CH3O
and enantiomer
Iodamide ï·ö·da·mïda,5-Diacetamido-2,4,6-tri-iodo-m-toluic acid; C12H11I3N2O4; 440-58-4Contrast medium
I
I
I
COOH
NH3C
O HN CH3
OH
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2-170Iodinated Glycerol (BAN)
A mixture of iodinated dimers of glycerolExpectorant
Iodipamide see Adipiodone
Iodixanol ï·ö·diks·a·nolrac-N,N¢,N¢¢,N¢¢¢-Tetrakis(2,3-dihydroxypropyl)-2,2¢,4,4¢,6,6¢-hexaiodo-5,5¢-[2-hydroxytrimethylenebis(acetylimino)]di-isophthalamide; C35H44I6N6O15; 92339-11-2; VISIPAQUEContrast medium
I
I
N
I
Ac
HN
O
OHH
OH
HNO
OHHOHHO
OHHO
HN
HOOHH
O
HN
Ac
I
N
I
I H OH
mixture of isomers
Iodofenphos (BAN) ï·ö·dö·fen·fosO-(2,5-Dichloro-4-iodophenyl) O,O-dimethyl phosphorothioate; C8H8Cl2O3PS;18181-70-9; ¨NUVAN STAYKIL*Insecticide; acaricide
P
S
OMe
O
I
Cl
Cl
OMe
Iodothiouracil ï·ö·dö·thï·ö·ûr·ra·sil(1) 2,3-Dihydro-5-iodo-2-thioxopyrimidin-4(1H)-one;(2) 5-iodo-2-thiouracil; C4H3IN2OS; 5984-97-4Antithyroid
NH
N S
O
I
H
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2-171Iodoxamic Acid ï·ö·doks·a·mik
3,3¢-(4,7,10,13-Tetraoxahexadecanedioyldiamino)bis(2,4,6-tri-iodobenzoic acid);C26H26I6N2O10; 31127-82-9Meglumine Iodoxamate 51764-33-1 ENDOBILContrast medium
II
I
COOH
N
O
H
CH2 CH2 O CH2 CH2 N
COOH
I
IIO
H4
Iofendylate (iophendylate) ï·ö·fen·di·lätEthyl (RS)-10-(4-iodophenyl)undecanoate; C19H29IO2; 99-79-6; MYODILContrast medium
I
COOEt
H Me
and enantiomer
Ioflupane[123I] ï·ö·floo·pänMethyl (1R,2R,3R,5S)-8-(3-fluoropropyl)-3-([123I]-4-iodophenyl)-8-azabicyclo[3.2.1]octane-2-carboxylate; C18H23F123INO2; 155798-07-5Diagnostic agent
NH
COOMe
F
H
122I
Ioglicic Acid ï·ö·glï·sik5-Acetamido-2,4,6-tri-iodo-N-[(methylcarbamoyl)methyl]isophthalamic acid;C13H12I3N3O5; 49755-67-1Contrast medium
II
I
COOH
AcHNN
NHMe
O
OH
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2-172Ioglycamic Acid ï·ö·glï·ka·mik
3,3¢-[Oxybis(methylenecarbonylimino)]bis(2,4,6-tri-iodobenzoic acid);C18H10I6N2O7;2618-25-9Meglumine Ioglycamate 14317-18-1 BILIGRAMContrast medium
HI
IIO
N
I
N
I
I
COOH
O
O
COOH
H
�Iohexol ï·ö·heks·olN,N¢-Bis(2,3-dihydroxypropyl)-5-[N-(2,3-dihydroxypropyl)acetamido]-2,4,6-tri-iodoisophthalamide; C19H26IN3O9; 66108-95-0Contrast medium
II
I
NN OH
HOO
H OH
AcHHO
N OHOH OH
mixture of isomers
*
* *
H
H
Iomeprol ï·ö·me·prolN,N¢-Bis(2,3-dihydroxypropyl)-2,4,6-tri-iodo-5-(N-methylglycollamido)-isophthalamide; C17H22I3N3O8; 78649-41-9Contrast medium
II
I
NN OHHO
O
H OH
Me
O
N OHOH OH
H
mixture of isomers
H
�Iopamidol ï·ö·pa·mi·dol(S)-N,N¢-[Bis[2-hydroxy-1-(hydroxymethyl)ethyl]-2,4,6-tri-iodo-5-lactamido-isophthalamide; C17H22I3N3O8; 62883-00-5; NIOPAMContrast medium
NH
OHHO
HN OHN
H
H3C
O
II
I OOH
O
HO H
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2-173�Iopanoic Acid ï·ö·pa·nö·ik
(RS)-2-(3-Amino-2,4,6-tri-iodobenzyl)butyric acid; C11H12I3NO2; 96-83-3;CISTOBIL; TELEPAQUEContrast medium used in cholecystography
I
NH2
I
I
CH3
H COOH
and enantiomer
Iopentol ï·ö·pen·tolN,N¢-Bis(2,3-dihydroxypropyl)-5-[N-(2-hydroxy-3-methoxypropyl)acetamido]-2,4,6-tri-iodoisophthalamide; C20H28I3N3O9; 89797-00-2;Contrast medium
II
I
N
HN OH
MeO
H OH
AcHHO
HN OHO
H OH
O
mixture of isomers
Iophendylate see Iofendylate
Iopromide ï·ö·prö·mïdN,N¢-Bis(2,3-dihydroxypropyl)-2,4,6-tri-iodo-5-(2-methoxyacetamido)-N-methylisophthalamide; C18H24I3N3O8; 73334-07-3; ULTRAVISTContrast medium
II
I
NN OH
O
H OH
N OHOH OH
MeO
MeO
mixture of isomers
H
H
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2-174Iopronic Acid ï·ö·pro·nik
2-[2-(3-Acetamido-2,4,6-tri-iodophenoxy)ethoxymethyl]butyric acid;C15H18I3NO5; 37723-78-7Diagnostic aid
II
OO CH3
COOH
NHAc
H
I
and enantiomer
Iopydol ï·ö·pï·dol(RS)-1-(2,3-Dihydroxypropyl)-3,5-di-iodo-4-pyridone; C8H9I2NO3; 5579-92-0;HYTRAST*Contrast medium
N OH
OH OH
I
I
and enantiomer
Iopydone ï·ö·pï·dön3,5-Di-iodo-4-pyridone; C5H3I2NO; 5579-93-1; HYTRAST*Contrast medium
N
I I
O
H
Iotalamic Acid (iothalamic acid) ï·ö·ta·la·mik5-Acetamido-2,4,6-tri-iodo-N-methylisophthalamic acid; C11H9I3N2O4; 2276-90-6Meglumine Iotalamate 13087-53-1; CARDIO-CONRAY*; CONRAY 280; RETROCONRAYSodium Iotalamate 17692-74-9; CARDIO-CONRAY*; CONRAY 325; CONRAY 420;GASTRO-CONRAYContrast medium
II
I
AcHNNHMe
O
COOH
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2-175Iotrolan ï·ö·trö·lan
N,N¢,N¢¢,N¢¢¢-Tetrakis(2,3-dihydroxy-1-hydroxymethylpropyl)-2,2¢,4,4¢,6,6¢-hexaiodo-5,5¢-(N,N¢-dimethylmalonyldi-imino)di-isophthalamide; C37H48I6N6O18;79770-24-4Contrast medium (non-ionic)
HOOH
OH
Me
NHO
OH
HO
OHN
O
HN
I
I IO
OHHO
OH
Me
NOH
OH
OH
O NH
O
HN
I
IIO
mixture of isomers
Iotroxic Acid ï·ö·troks·ik3,3¢-(3,6,9-Trioxaundecanedioyldi-iminobis(2,4,6-tri-iodobenzoic acid);C22H18I6N2O9; 51022-74-3Meglumine Iotroxate BILISCOPINContrast medium
I
IIO
NH
COOH
I
NH
I
I
COOH
O
CH2 OCH2 3
Ioversol ï·ö·ver·solN,N¢-Bis(2,3-dihydroxypropyl)-5-[N-(2-hydroxyethyl)glycollamido]-2,4,6-tri-iodoisophthalamide; C18H24I3N3O9; 87771-40-2; MP-328Contrast medium used for coronary arteriography, cerebral angiography and other applications
II
I
N
HN OHHO
H OH
HN OHO
H OH
HOO
O
mixture of isomers
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2-176Ioxaglic Acid ï·oks·a·glik
N-(2-Hydroxyethyl)-2,4,6-tri-iodo-5-[2¢,4¢,6¢-tri-iodo-3¢-(N-methylacetamido)-5¢-methylcarbamoylhippuramido]isophthalamic acid; C24H21I6N5O8; 59017-64-0Meglumine Ioxaglate 59018-13-2; HEXABRIX*Sodium Ioxaglate 67992-58-9; HEXABRIX*Contrast medium
H
I I
I
NAcN
CONHMe
O
HO
O
N
COOH
N
I
I I
O Me
H
H
�Ipratropium Bromide i·pra·trö·pë·um(1R,3r,5S,8r)-8-Isopropyl-3-(±)-tropoyloxytropanium bromide; C20H30BrNO3;22254-24-6; ATROVENT; COMBIVENT*; DUOVENT*; RINATECAnticholinergic; bronchodilator
N
Pr i
O
O
Me
OH
H
Br_
and enantiomer
+
Iprindole ï·prin·dôl5-(3-Dimethylaminopropyl)-6,7,8,9,10,11-hexahydrocyclo-oct[b]indole;C19H28N2; 5560-72-5Iprindole Hydrochloride 20432-64-8; PRONDOLAntidepressant
NMe2N
Iproclozide i·prö·klö·zïd2-(4-Chlorophenoxy)-2¢-isopropylacetohydrazide; C11H15ClN2O2;3544-35-2Monoamine oxidase inhibitor
Cl
ONHNHPr i
O
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2-177Iproniazid i·prö·nï·a·zid
2¢-Isopropylisonicotinohydrazide; C9H13N3O; 54-92-2Iproniazid Phosphate 305-33-9Monoamine oxidase inhibitor
NHNHPr i
O
N
Ipronidazole i·prö·nï·da·zôl2-Isopropyl-1-methyl-5-nitroimidazole; C7H11N3O2; 14885-29-1Antiprotozoan
N
NO2N
Me
Pr i
Iproplatin i·prö·pla·tin(OC-6-33)-Dichlorodihydroxybis(isopropylamino)platinum; C6H20Cl2N2O2Pt;62928-11-4; JM-9Cytotoxic
PtCl
HOCl
NH2Pr iOH
NH2Pr i
Ipsalazide ip·sa·la·zïd4¢-(3-Carboxy-4-hydroxyphenylazo)hippuric acid; C16H13N3O6;80573-03-1Ipsalazide Sodium BX 650 ATreatment of ulcerative colitis
N N
COOH
OHNHOOC
O
H
Ipsapirone ip·sa·pîr·rön2-{4-[4-(Pyrimidin-2-yl)piperazin-1-yl]butyl}-1,2-benzothiazol-3(2H)-one 1,1-dioxide; C19H23N5O3S; 95847-70-4Ipsapirone Hydrochloride 92589-98-5; Bay q 7821Anxiolytic
NN
O
N N
N
SOO
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2-178Irbesartan er·be·sar·tan
2-Butyl-3-{4-[2-(1H-tetrazol-5-yl)phenyl]benzyl}-1,3-diazaspiro[4.4]non-1-en-4-one; C25H28N6O; 138402-11-6; APROVELAngiotensin II receptor antagonist; antihypertensive
N
N N
NH
N
NO Bun
Irinotecan i·ri·nö·të·kan(S)-4,11-Diethyl-3,4,12,14-tetrahydro-4-hydroxy-3,14-dioxo-1H-pyrano[3¢,4¢:6,7]-indolizino[1,2-b]quinolin-9-yl [1,4¢-bipiperidine]-1¢-carboxylate;C33H38N4O6; 97682-44-5Irinotecan Hydrochloride 136572-09-3 (trihydrate); U-101,440EDNA topoisomerase-I inhibitor; antineoplastic
N
N O
O
OHO Et
H
O
ON
NEt
Iron Sucrose (BAN) îr·on sü·krösA complex of iron(III) hydroxide with sucrose containing traces of sodium chlorideand sodium hydroxide corresponding approximately to the formula:[{Na0.46[FeO1.6(OH)0.26(H2O)0.54][C12H22O11]2.61} +0.18NaOH + 0.02NaCl]n (n =43) (mol. wt., 43,200 approx); iron(III) hydroxide–sucrose complex; saccharatediron oxide; 8047-67-4; VENOFER
Treatment of anaemia
Irtemazole er·te·ma·zôl(RS)-5-(a-Imidazol-1-ylbenzyl)-2-methylbenzimidazole; C18H16N4;115574-30-6; R 60844Uricosuric agent
NN N
N Me
H
H
and enantiomer
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2-179Isamoxole ï·sa·moks·ôl
N-Butyl-2-methyl-N-(4-methyl-1,3-oxazol-2-yl)propionamide; C12H20N2O2; 57067-46-6Treatment of bronchial asthma
N
O N CH3
Me
Me
O
Me
Isatoribine ï·sa·tor·ri·bën5-Amino-3-(b-D-ribofuranosyl)[1,3]thiazolo[4,5-d]pyrimidine-2,7(3H,6H)-dione;C10H12N4O6S;122970-40-5Immunomodulator
O
OH
N
S
OHHO
HN
N
O
H2N
O
Isepamicin ï·se·pa·mï·sin4-O-(6-Amino-6-deoxy-a-D-glucopyranosyl)-1-N-(3-amino-L-lactoyl)-2-deoxy-6-O-(3-deoxy-4-C-methyl-3-methylamino-b-L-arabinopyranosyl)-D-streptamine;C22H43N5O12; 58152-03-7; Sch 21420Antibacterial
NH2NH
OH
O
O
HOMe
OOH
OH
HO
NH2
O
H2N
O
H OH
HO
NHMe
�Isoaminile ï·sö·am·i·nïl4-Dimethylamino-2-isopropyl-2-phenylpentanonitrile; C16H24N2; 77-51-0Isoaminile Citrate 126-10-3; DIMYRILAntitussive
NMe2
NC Pri H Me
mixture of 4 stereoisomers
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2-180Isobuzole see Glysobuzole
Isocarboxazid ï·sö·kar·boks·a·zid2¢-Benzyl-5-methyl-1,2-oxazole-3-carbohydrazide; C12H13N3O2; 59-63-2; MARPLANAntidepressant
N
N O
N
O
MeH
H
�Isoconazole ï·sö·ko·na·zôl(RS)-1-[2,4-Dichloro-b-(2,6-dichlorobenzyloxy)phenethyl]imidazole;C18H14Cl4N2O; 27523-40-6�Isoconazole Nitrate 40036-10-0; R 15454; TRAVOGYNAntifungal
O
N
N
Cl
Cl ClCl
and enantiomer
�Isoetarine (isoetharine) ï·sö·e·ta·rën1-(3,4-Dihydroxyphenyl)-2-isopropylaminobutan-1-ol; C13H21NO3;530-08-5Beta-adrenoceptor agonist
HO
HO
H OH
HCH3
NHPri
mixture of 4 stereoisomers
Isoflupredone ï·sö·floo·pre·dön(1) 9a-Fluoro-11b,17a,21-trihydroxypregna-1,4-diene-3,20-dione;(2) 9a-fluoroprednisolone; C21H27FO5; 338-95-4Isoflupredone Acetate 338-98-7; ¨ PREDEF 2X*Corticosteroid
O
HF
Me
HMe
HO
OOH
OH
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2-181Isoflurane ï·sö·flûr·rän
2-Chloro-2-difluoromethoxy-1,1,1-trifluoroethane; C3H2ClF5O;26675-46-7; AERRANE; FORANEAnaesthetic
F3C O
Cl HCHF2
and enantiomer
Isomalt (BAN) ï·sö·maltA mixture of equal parts of 6-O-(a-D-glucopyranosyl)-D-glucitol and1-O-(a-D-glucopyranosyl)-D-mannitol; BAY i 3930Sweetening agent
Isometamidium Chloride ï·sö·me·ta·mi·dë·um8-(3-m-Amidinophenyl-1-triazeno)-3-amino-5-ethyl-6-phenylphenanthridiniumchloride; C28H26ClN7; 34301-55-8Antiprotozoan
NN
NH2
EtNN
H2N
NHH Cl+ _
Isomethadone ï·sö·me·tha·dön(RS)-6-Dimethylamino-5-methyl-4,4-diphenylhexan-3-one; C21H27NO;466-40-0Opioid analgesic
H3C NMe2
O
Ph Ph
MeH
and enantiomer
Isometheptene ï·sö·me·thep·tën(RS)-1,5-Dimethylhex-4-enyl(methyl)amine; C9H19N; 503-01-5�Isometheptene Mucate MIDRID*Sympathomimetic
Me2CNHMe
H Me
and enantiomer
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2-182�Isoniazid ï·sö·nï·a·zid
Isonicotinohydrazide; C6H7N3O; 54-85-3; RIFATER*; RIFINAH*; RIMACTAZID*;RIMIFONAntitubercular
N
N
O
NH2
H
�Isophane InsulinA buffered suspension of insulin with the isophanic equivalent of protamine andzinc chloride; isophane insulin (NPH); HYPURIN ISOPHANE; HUMAN INSULATARD;HUMULIN I; PORK INSULATARDHypoglycaemic
Isoprazone ï·so·pra·zön1-(4-Amino-2-methyl-5-phenylpyrrol-3-yl)-2-methylpropan-1-one; C15H18N2O;56463-68-4; L 11809; DL-809-IT; MDL-809Analgesic
N Me
H2N Me
O
Me
H
Isoprednidene ï·sö·pred·ni·dën11b,17a,21-Trihydroxy-16-methylenepregna-4,6-diene-3,20-dione; C22H28O5;17332-61-5Corticotrophin inhibitor
O
HH
Me
HMe
HO
OOH
OHCH2
Isoprenaline ï·sö·pre·na·lën(RS)-1-(3,4-Dihydroxyphenyl)-2-isopropylaminoethanol; C11H17NO3; 7683-59-2�Isoprenaline Hydrochloride isoproterenol hydrochloride (USAN);51-30-9; ¨MIN-I-JET ISOPRENALINE; PIB*; SAVENTRINE;�Isoprenaline Sulphate 6700-39-6; (dihydrate); 299-95-6 (anhydrous) INTALCOMPOUND*; MEDIHALER-ISOBeta-adrenoceptor agonist
NHPr i
HO
OH
H OH
and enantiomer
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2-183Isopropamide Iodide ï·sö·prö·pa·mïd
(3-Carbamoyl-3,3-diphenylpropyl)di-isopropylmethylammonium iodide;C23H33IN2O; 71-81-8Anticholinergic
H2NNPr i
2
O
Ph Ph
Me
I+ _
Isosorbide ï·sö·sor·bïd1,4:3,6-Dianhydro-D-glucitol; C6H10O4; 652-67-5Treatment of hydrocephalus
O
OH
H
OHH
HHO
�Isosorbide Dinitrate ï·sö·sor·bïd dï·nï·trät1,4:3,6-Dianhydro-D-glucitol 2,5-dinitrate; sorbide nitrate; C6H8N2O8;87-33-2; CEDOCARD; IMTACK; ISOKET; ISORDIL; JERIDIN; SONI-SLO; SORBICHEW;SORBID; SORBITRATE; TEMBIDSVasodilator
O
OH
H
ONO2H
HO2NO
�Isosorbide Mononitrate ï·sö·sor·bïd mo·nö·nï·trät1,4:3,6-Dianhydro-D-glucitol 5-nitrate; C6H9NO6; 16051-77-7; ANGEZE; ANGITATE;DYNAMIN; ELANTAN; IMDUR; ISIB; ISMO; ISOTRATE; MCR 50; MODISAL; MONIT;MONO-CEDOCARD; MONODUR; MONOMAXVasodilator
O
OH
H
OHH
HO2NO
�Isothipendyl(RS)-Dimethyl[1-(pyrido[3,2-b][1,4]benzothiazin-10-ylmethyl)ethyl]amine;C16H19N3S; 482-15-5
S
NNMe2
H Me
and enantiomer
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2-184Isotiquimide ï·sö·tï·kwi·mïd
5,6,7,8-Tetrahydro-4-methylquinoline-8-carbothioamide; C11H14N2S;56717-18-1Isotiquimide Hydrochloride 56717-19-2; Wy 24377Anti-ulcer agent
N
Me
S NH2
H
and enantiomer
�Isotretinoin ï·sö·tre·ti·nö·in(1) (13Z)-15-Apo-b-caroten-15-oic acid; (2) (2Z,4E,6E,8E)-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraenoic acid;(3) 13-cis-retinoic acid; C20H28O2; 4759-48-2; ISOTREX; ROACCUTANETreatment of acne
COOH
Me Me
Me
Me Me
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3-1Isoxepac ï·soks·ë·pak
6,11-Dihydro-11-oxodibenz[b,e]oxepin-2-ylacetic acid; C16H12O4; 55453-82-7; HP549; P720549Analgesic; anti-inflammatory
O
O
COOH
Isoxicam ï·soks·i·kam4-Hydroxy-2-methyl-N-(5-methyl-1,2-oxazol-3-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide; C14H13N3O5S; 34552-84-6Analgesic; anti-inflammatory
N
N
OOH
MeSOO
N OMe
Isoxsuprine ï·sok·sü·prën(1RS,2SR)-1-(4-Hydroxyphenyl)-2-[(1SR)-1-methyl-2-phenoxyethylamino]propan-1-ol; C18H23NO3; 395-28-8�Isoxsuprine Hydrochloride 579-56-6; ̈ DUVIVULINE; ̈ NAVILOX; ̈ ORALJECT
CIRCULON
Beta-adrenoceptor agonist
NO
HO
HO H
Me H H Me
H
and enantiomer
�Isradipine is·ra·di·pën(RS)-Isopropyl methyl 4-(2,1,3-benzoxadiazol-4-yl)-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate; C19H21N3O5; 75695-93-1; PRESCAL
Calcium antagonist
N Me
COOPr i
Me
MeOOC
N
ON
H
H
and enantiomer
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3-2�Itraconazole i·tra·ko·na·zôl
(±)-2-sec-Butyl-4-[4-(4-{4-[(2R*,4S*)-2-(2,4-dichlorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethoxy]phenyl}piperazin-1-yl)phenyl]-2,4-dihydro-1,2,4-triazol-3-one; C35H38Cl2N8O4;84625-61-6; SPORANOX
Antifungal
N
N
N
H
N
N
O Cl
ClN
N
N
OO
OH3CH Me
and enantiomer
Itramin Tosilate i·tra·min tö·s·ilät2-Nitratoethylammonium p-toluenesulphonate; C2H6N2O3.C7H8N3S;13445-63-1Vasodilator
H2NONO2
SO3H
Me
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3-3�Ivermectin ï·ver·mek·tin
A mixture of ivermectin components B1a and B1b; 70288-86-7Component B1a: (10E,14E,16E,22Z)-(1R,4S,5¢S,6R,6¢R,8R,12S,13S,20R,21R,24S)-6¢-[(S)-sec-Butyl]-21,24-dihydroxy-5¢,11,13,22-tetramethyl-2-oxo-(3,7,19-trioxatetracyclo[15.6.1.14,8.020,24]pentcosa-10,14,16,22-tetraene)-6-spiro-2¢-(perhydropyran)-12-yl 2,6-dideoxy-4-O-(2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyl)-3-O-methyl-a-L-arabino-hexopyranoside; 70161-11-4Component B1b: as described above replacing ‘6¢-[(S)-sec-Butyl]-’ by‘6¢-isopropyl-’ inserted after ‘21,24-dihydroxy-’; 70209-81-3;¨ EQVALAN; ̈ FUREXEL; ̈ IVOMEC; ̈ ORAMEC; ̈ PANOMEC
Anthelmintic
O
O
OOO
OO
O O
HO
Me
OH
H
H
OMe
MeH
HMe
H
OH
OMe
MeH
RH
CH3
Me
Me
B1a, R = Et
B1b, R = Me
Kallidinogenase ka·li·di·no·je·näzAn enzyme that splits the kinin, kallidin, from kininogen; 9001-01-8Enzyme
Kanamycin kä·na·mï·sinAn antimicrobial base produced by Streptomyces kanamyceticus;6-O-D-(3-amino-3-deoxy-a-glucopyranosyl)-4-O-(6-amino-6-deoxy-a-D-glucopyranosyl)-2-deoxy-D-streptamine; kanamycin A; C18H36N4O11;59-01-8;�Kanamycin Sulphate 25389-94-0; KANNASYN SOLUTION
�Kanamycin Acid Sulphate KANNASYN POWDER
Antibiotic
NH2NH2
OH
O
O
HOHO
H2N
OH OOH
NH2
HO
OH
O
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3-4Ketamine kë·ta·mën
2-(2-Chlorophenyl)-2-methylaminocyclohexanone; C13H16ClNO;4740-88-1Ketamine Hydrochloride 1867-66-9; KETALAR; ̈ KETASET; ̈ VETALAR
Anaesthetic
OCl
NHMe
and enantiomer
Ketanserin kë·tan·se·rin3-{2-[4-(4-Fluorobenzoyl)piperidino]ethyl}quinazoline-2,4(1H,3H)dione;C22H22FN3O3; 74050-98-9; R41468Ketanserin Tartrate R49945Serotonin receptor antagonist
N
N
O
O
O
FN
H
�Ketazolam kë·tä·zö·lam11-Chloro-8,12b-dihydro-2,8-dimethyl-12b-phenyl-4H-[1,3]oxazino[3,2-d][1,4]benzodiazepine-4,7(6H)-dione; C20H17ClN2O3;27223-35-4
N
N
O
Me O
ClO
Me
Ketobemidone kë·tö·be·mi·dön1-(4-m-Hydroxyphenyl-1-methyl-4-piperidyl)propan-1-one; cetobemidone (rINN);C15H21NO2; 469-79-4Opioid analgesic
OH
O
CH3
MeN
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3-5�Ketoconazole kë·tö·kon·a·zôl
1-Acetyl-4-{4-[2-(2,4-dichlorophenyl)-r-2-(1H-imidazol-1-ylmethyl)-1,3-dioxolan-c-4-ylmethoxy]phenyl}piperazine; C26H28Cl2N4O4; 65277-42-1; NIZORAL
Antifungal
OO
N
NCl
ClO
N
NAc
H
and enantiomer
�Ketoprofen kë·tö·prö·fen2-(3-Benzoylphenyl)propionic acid; C16H14O3; 22071-15-4; ALRHEUMAT; KETOCID;KETOZIP;¨KETOFEN; ORUDIS; ORUVAIL; POWERGEL
Analgesic; anti-inflammatory
and enantiomer
H Me
COOH
O
Ketorolac kë·to·rö·lak(RS)-5-Benzoyl-2,3-dihydro-1H-pyrrolizine-1-carboxylic acid; C15H13NO3; 74103-06-3Ketorolac Trometamol ketorolac tromethamine (USAN); 74103-07-4; ACULAR;TORADOL
Analgesic; anti-inflammatory
and enantiomer
N
COOH
O
H
Ketotifen kë·tot·i·fen4-(1-Methylpiperidin-4-ylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophen-10(9H)-one; C19H19NOS; 34580-13-7Ketotifen Fumarate 34580-14-8; ZADITEN
Histamine H1-receptor antagonist
S
O
NMe
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3-6Kitasamycin ki·tä·sa·mï·sin
An antibiotic produced by Streptomyces kitasatoensis; it consists mainly ofkitasamycins A4 and A5; leucomycin; 1392-21-8Kitasamycin A4: (10E,12E)-(3R,4R,5S,6R,8R,9R,15R)-3-Acetoxy-5-[4-O-(4-O-butyryl-2,6-dideoxy-3-C-methyl-a-L-ribo-hexopyranosyl)-3,6-dideoxy-3-dimethylamino-b-D-gluco-hexopyranosyloxy]-6-formylmethyl-9-hydroxy-4-methoxy-8-methylhexadeca-10,12-dien-15-olide; C41H67NO15
Kitasamycin A5: (10E,12E)-(3R,4R,5S,6R,8R,9R,15R)-5-[4-O-(4-O-butyryl-2,6-dideoxy-3-C-methyl-a-L-ribo-hexopyranosyl)-3,6-dideoxy-3-dimethylamino-b-D-gluco-hexopyranosyloxy]-6-formylmethyl-3,9-dihydroxy-4-methoxy-8-methylhexadeca-10,12-dien-15-olide; C39H65NO14; 18361-45-0Antibacterial (veterinary)
kitasamycin A5
Me
O
O
OH
NMe2
O
O
Me
OHO CH3
OMe
O
O
HO
Me
Me
OMeHO
CHO
Labetalol la·bë·ta·lol2-Hydroxy-5-[1-hydroxy-2-(1-methyl-3-phenylpropylamino)ethyl]benzamide;C19H24N2O3; 36894-69-6�Labetalol Hydrochloride 32780-64-6; TRANDATE
Alpha- and beta-adrenoceptor antagonist
N
MeH
OHHCONH2
OH
H
mixture of 4 isomers
* *
�Lachesine Chloride (BAN)2-(Benziloyloxyethyl)ethyldimethylammonium chloride; C20H26ClNO3;1164-38-1
ONMe2
O
OH
Et
Cl+ _
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3-7Lacidipine la·si·di·pën
Diethyl (E)-4-{2-[(tert-butoxycarbonyl)vinyl]phenyl}-1,4-dihydro-2,6-dimethylpyridine-3,5-dicarboxylate; C26H33NO6; 103890-78-4; MOTENS
Antihypertensive
COOBu tEtOOC
Me
COOEt
MeNH
�Lactitol lak·ti·tol4-O-(b-D-Galactopyranosyl)-D-glucitol; C12H24O11; 585-86-4; IMPORTAL
Osmotic laxative
CH2OH
OHH
HHO
H
H OH
CH2OH
O
HO
OH
OHOOH
�Lactulose lak·tü·lös4-O-(b-D-Galactopyranosyl)-D-fructose; C12H22O11; 4618-18-2; DUPHALAC; LACTUGAL
Laxative
O OHHO
HO
OH
O
OH
OH
O
HO
HO
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3-8Laidlomycin läd·lö·mï·sin
(2S,3R,4R)-4-[(2S,5R,7S,8R,9S)-9-Hydroxy-2,8-dimethyl-2-{(2S,2¢R,3¢S,5R,5¢R)-octahydro2,3¢-dimethyl-5¢-[(2S,3S,5R,6R)-tetrahydro-6-hydroxy-6-hydroxymethyl-3,5-dimethyl-2H-pyran2-yl]-2,2¢-bifuran-5-yl}-1,6-dioxaspiro[4.5 ]dec-7-yl]-2-methyl-3-propionyloxypentanoic acid; C37H62Ol2; 56283-74-0Laidlomycin Propionate Potassium 84799-02-0; RS-11988Coccidiostat; growth promoter (veterinary)
OOO O
MeO
HO
Me
Me H
EtCOO COOH
Me
H
Me
H
Me Me
Me
OHHO
H
H
Lamivudine la·miv·ü·dën(1) 4-Amino-1-[(2R,5S)-2-hydroxymethyl-1,3-oxathiazolan-5-yl]pyrimidin-2(1H)-one; (2) 1-[(2R,5S)-2-hydroxymethyl-1,3-oxathiazolan-5-yl]cytosine; C8H11N3O3S;134678-17-4; COMBIVIR*; EPIVIR
Reverse transcriptase inhibitor; antiviral
NH2
ON
N
O
SHO
Lamotrigine la·mo·tri·jën6-(2,3-Dichlorophenyl)-1,2,4-triazine-3,5-diyldiamine; C9H7ClN5; 84057-84-1;LAMICTAL
Anticonvulsant
N
NN
Cl
Cl
H2N NH2
Lamtidine lam·ti·dën3-Amino-1-methyl-1H-1,2,4-triazol-5-yl[3-(a-piperidino-m-tolyloxy)propyl]amine;C18H28N6O; 73278-54-3; AH 22216Histamine H2-receptor antagonist
NO N
N
NN
NH2
MeH
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3-9��Lanatoside C la·na·to·sïd
3-[(O-b-D-Glucopyranosyl-(1® 4)-O-3-acetyl-2,6-dideoxy-b-D-ribo-hexopyranosyl-(1® 4)-O-2,6-dideoxy-b-D-ribo-hexopyranosyl-(1® 4)-O-2,6-dideoxy-b-D-ribo-hexopyranosyl)oxy]-12,14-dihydroxy-3b,5b,12b-card-20(22)-enolide; C49H76O20;17575-22-3
OMe
OAc
O
OO
OH
OH
HOCH2
OMeO
OMe
OH
OR
OH
HO
O
Me
H
H
H
OH
HOMe
O
H
R =
Lanproston lan·pros·ton(Z)-7-[(1R,2R,3R,5S)-2-{(E)-2-[2-(3-Chlorophenoxymethyl)-1,3-dioxolan-2-yl]vinyl}-3,5-dihydroxycyclopentyl]hept-5-enoic acid; C24H31ClO7; 131349-68-3Luteotropic agent (veterinary)
HO
HO
H
COOH
O
Cl
O OH
Lanreotide lan·rë·ö·tïdS2,S7-Cyclo[3-(2-naphthyl)-D-alanyl-L-cysteinyl-L-tyrosyl-D-tryptophyl-L-lysyl-L-valyl-L-cysteinyl-L-threoninamide]; C54H69N11O10S2; 108736-35-2; BIM 23014; BN52030; 27984-74-1Somatostatin analogue; treatment of neuroendocrine tumours and acromegaly
HNH2N H
O
Cys-Tyr-D-Trp-Lys-Val-Cys-Thr-NH2
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3-10Lansoprazole lan·so·pra·zôl
2-({3-Methyl-4-(2,2,2-trifluoroethoxy)-2-pyridyl)methyl}sulfinylbenzimidazole;C16H14F3N3O2S; 103577-45-3; ZOTON
Treatment of peptic ulcer
N
N SN
O CF3
MeO
H
Lasalocid la·sal·ö·sid6-[(3R,4S,5S,7R)-7-{(2S,3S,5S)-5-Ethyl-5-[(2R,5R,6S)-5-ethyltetrahydro-5-hydroxy-6-methyl-2H-pyran-2-yl]tetrahydro-3-methyl-2-furyl}4-hydroxy-3,5-dimethyl-6-oxononyl]-2-hydroxy-m-toluic acid; C34H54O8; 25999-31-9Lasalocid Sodium ̈ AVATEC
Coccidiostat
COOH
HO
Me
O OH HMe
Et
OH
O
Me EtMe
OH
Me
Et
�Latamoxef la·ta·moks·ef(1)(S)-N-[(6R,7R)-2-Carboxy-7-methoxy-3-(1-methyl-1H-tetrazol-5-ylthiomethyl)-8-oxo-5-oxa-1-azabicyclo[4.2.0]oct-2-en-7-yl]-2-(4-hydroxyphenyl)malonamicacid; (2) (7R)-7-[(S)-2-Carboxy-p-hydroxyphenylacetamido]-7-methoxy-3-(1-methyltetrazol-5-ylthiomethyl)-1-oxa-3-cephem-4-carboxylic acid; C20H20N6O9S;64952-97-2Latamoxef Disodium moxalactam disodium (USAN); 64953-12-4
H
N N
NNS
OMe
HO
COOH
OH
O
HHOOC
O N
NMe
Latanoprost la·ta·nö·prostIsopropyl (Z)-(9S,11R,15R)-9,11,15-trihydroxy-17-phenyl-18,19,20-trinorprost-5-enoate; C26H40O5; 130209-82-4; XALATAN
Reduction of intraocular pressure; treatment of glaucoma
COOPri
HO H
HO
HO
H
H
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3-11�Laudexium Metilsulfate
1,1¢,2,2¢,3,3¢,4,4¢-Octahydro-6,6¢,7,7¢-tetramethoxy-1,1¢-bis(3,4-dimethoxybenzyl)-2,2¢-dimethyl-N,N¢-dodecamethylenedi-isoquinolinium di(methylsulfate);C54H80N2O16S2; 3253-60-9
CH2 [CH2 ]1 0 CH2NMeO
MeO
OMe
MeO
Me
NOMe
OMe
OMe
OMe
Me+ +
CH3OSO3_
2
�Laurolinium Acetate4-Amino-1-dodecyl-2-methylquinolinium acetate; C24H38N2O2; 146-37-2
N Me
NH2
CH2 [CH2 ]1 0 CH3
CH3 COO
+_
Lauromacrogol lor·ro·ma·krö·golA mixture of monolauryl ethers of polyoxyethylene glycols having a statisticalaverage of 8 ethylene oxide groups per molecule; 9015-55-8Non-ionic surfactant
�Lavoltidine{1-Methyl-5-[3-(a-piperidino-m-tolyloxy)propylaminol]-1H-1,2,4-triazol-3-yl}methanol; loxtidine; C19H29N5O2; 76956-02-0
NO N
N
NN
Me
OH
H
Lazabemide la·za·be·mïdN-(2-Aminoethyl)-5-chloropyridine-2-carboxamide; C8H10ClN3O; 103878-84-8Antiparkinsonian
NNH
NH2
Cl
O
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3-12Leflunomide le·floo·nö·mïd
a,a,a-Trifluoro-5-methyl-1,2-isoxazol-4-ylcarboxo-p-toluidide; C12H9F3N2O2;75706-12-6Immunomodulator; antirheumatic
N
CF3
ON
Me
O
H
Lenercept len·er·sept1— 182-tumour necrosis factor receptor (human reduced), (182— 104¢)-proteinwith 104-330-immunoglobulin G 1 (human clone pTJ5 cg 1reduced); C1993H3112N562O624S34; 156679-34-4; Ro 45-2081Tumour necrosis factor antagonist; treatment of septic shock
lenercept has the following amino acid sequence (Cys—Cys bridges in the range 1-182shown):
LVPHLGDREK RDSVCPQGKY IHPQNNSICC
TKCHKGTYLY NDCPGPGQDT DCRECESGSF
TASENHLRHC LSCSKCRKEM GQVEISSCTV
DRDTVCGCRK NQYRHYWSEN LFQCFNCSLC
LNGTVHLSCQ EKQNTVCTCH AGFFLRENEC
VSCSNCKKSL ECTKLCLPQI ENVKGTEDSG
TTDKTHTCPP CPAPELLGGP SVFLFPPKPK
DTLMISRTPE VTCVVVDVSH EDPEVKFNWY
VDGVEVHNAK TKPREEQYNS TYRVVSVLTV
LHQDWLNGKE YKCKVSNKAL PAPIEKTISK
AKGQPREPQV YTLPPSREEM TKNQVSLTCL
VKGFYPSDIA VEWESNGQPE NNYKTTPPVL
DSDGSFFLYS KLTVDKSRWQ QGNVFSCSVM
HEALHNHYTQ KSLSLSPGK
![Page 375: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/375.jpg)
3-13Lenograstim le·nö·gra·stim
Recombinant human granulocyte colony stimulating factor (glycosylated)expressed by a transformed Chinese hamster ovary cell line; C840Hl330N222O242S8(non-glycosylated protein); 62683-29-8; rHuG-CSF; GRANOCYTE
Immunostimulamt
For labelling purposes, the following three-letter code, to indicate the method ofproduction, is approved:
(rch) produced from genetically engineered Chinese hamster ovary cells
Lenograstim has the following amino acid sequence:
TPLGPASSLP QSFLLKCLEQ VRKIQGDGAA
LQEKLCATYK LCHPEELVLL GHSLGIPWAP
LSSCPSQALQ LAGCLSQLHS GLFLYQGLLQ
ALEGISPELG PTLDTLQLDV ADFATTIWQQ
MEELGMAPAL QPTQGAMPAF ASAFQRRAGG
VLVASHLQSF LEVSYRVLRH LAQP
*
*indicates site of glycosylation
Lepirudin le·pi·roo·din1-L-Leucine-2-L-threonine-63-desulfohirudin (Hirudo medicinalis isoform HV1);C287H440N80O111S6; 138068-37-8; REFLUDAN
Antithrombotic; anticoagulant
lepirudin has the following amino acid sequence:
LTYTDCTESG QNLCLCEGSN VCGQGNKCIL
GSDGEKNQCV TGEGTPKPQS HNDGDFEEIP
EEYLQ
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3-14Lercanidipine ler·ka·ni·di·pën
(RS)-2-[3,3-Diphenylpropyl(methyl)amino]-1,1-dimethylethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate; C36H41N3O6;100427-26-7Lercanidipine Hydrochloride 132866-11-6; ZANIDIP
Calcium antagonist
H
ON
O Me Me Me
MeMe
MeOOC
NO2
N
H
and enantiomer
Letrozole le·trö·zôl4,4¢-(1H-1,2,4-Triazol-1-ylmethylene)dibenzonitrile; C17H11N5;112809-51-5; FEMARA
Aromatase inhibitor; antineoplastic
N
N
N
NC
CN
Leuprorelin loo·prö·rë·linC59H84N16O12; 53714-56-0Leuprorelin Acetate leuprolide acetate (USAN); 74381-53-6; PROSTAP
Cytotoxic5–oxoPro–His–Trp–Ser–Tyr–D-Leu–Leu–Arg–Pro–NHEt
Levallorphan lëv·a·lor·fan(-)-9a-Allylmorphinan-3-ol; C19H25NO; 152-02-3Levallorphan Tartrate 71-82-9Opioid antagonist
N
HO
H CH2
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3-15�Levamfetamine (levamphetamine) lëv·am·fet·a·mën
(R)-a-Methylphenethylamine; (-)-amfetamine; C9H13N; 156-34-3Sympathomimetic
NH2
MeH
Levamisole le·vam·i·sôl(S)-2,3,5,6-Tetrahydro-6-phenylimidazo[2,1-b][1,3]thiazole; C11H12N2S; 14769-73-4 ̈ LEVIPOR; ̈ NILVAX*�Levamisole Hydrochloride 16595-80-5; ̈ ANTHELPOR; ̈ ARMADOSE; ̈ BIONEM;¨CHANAVERM; ¨COMBINEX*; ¨DECAZOLE; ¨DUPHAMISOLE; ¨LEVACIDE; ¨LEVACURE;¨LEVADIN; ̈ LEVAM WORMAWAY; ̈ LEVAPAS; ̈ LEVASOL; LEVIPOR; ̈ NEMICIDE; ̈ NILVERM;¨NILZAN*; ̈ RIDAVERM; ̈ RIPERCOL; ̈ SPARTAKON; ̈ SURE
Anthelmintic
N
N SH
Levcromakalim lev·kro·ma·ka·lim(1) N-[(3S,4R)-6-Cyano-3-hydroxy-2,2-dimethylchroman-4-yl]butane-4-lactam;(2) (3S,4R)-3-hydroxy-2,2-dimethyl-4-(2-oxopyrrolidin-1-yl)chroman-6-carbonitrile; C16H18N2O3; 94535-50-9Potassium channel activator
N
O
NC
MeMe
H
OH
OH
Levetiracetam lev·e·ti·ra·së·tam(S)-2-(2-Oxopyrrolidin-1-yl)butanamide; C8H14N2O2; 102767-28-2
Nootropic agent
H3C NH2
N O
O
H
Levobunolol lë·vö·bu·no·lol(S)-5-(3-tert-Butylamino-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalen-1-one;C17H25NO3; 47141-42-4Levobunolol Hydrochloride 27912-14-7; BETAGAN
Beta-adrenoceptor antagonist
O
OtBuHNHHO
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3-16Levobupivacaine lë·vo·bü·pi·va·kän
(S)-1-Butyl-2-piperidylformo-2 ,́6´-xylidide; C18H28N2O; 27262-47-1Levobupivacaine Hydrochloride 27262-48-2Local anaesthetic
NN
OMe
Bun
HMeH
Levocabastine lë·vö·ka·ba·stën(3S,4R)-1-(cis-4-Cyano-4-p-fluorophenylcyclohexyl)-3-methyl-4-phenylpiperidine-4-carboxylic acid; C26H29FN2O2; 79516-68-0Levocabastine Hydrochloride 79547-78-7; LIVOSTIN
Histamine H1-receptor antagonist
NCOOHNC
F
Me
H
�Levocarnitine lë·vö·kar·ni·tën(R)-3-Hydroxy-4-trimethylammoniobutyrate; C7H15NO3; 541-15-1Replacement therapy
Me3NO
_H OH O
+
�Levodopa lë·vö·dö·pa3-(3,4-Dihydroxyphenyl)-L-alanine; L-dopa; C9H11NO4; 59-92-7; BROCADOPA;MADOPAR*; SINEMET*Dopaminergic
COOHHO
HONH2H
Levofloxacin lë·vö·floks·a·sin(S)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid; C18H20FN3O4; 100986-85-4;TAVANIC
Antibacterial
N
N
N
OMe
F
O
COOH
Me
H
![Page 379: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/379.jpg)
3-17Levomenthol lë·vö·men·thol
(lR,2S,5R)-2-isopropyl-5-methylcyclohexanol; C10H20O; 2216-51-5Decongestant; carminative
Me
OH
Me Me
�Levomepromazine / Methotrimeprazine lë·vö·me·prö·ma·zën(R)-3-(2-Methoxyphenothiazin-10-yl)-2-methylpropyldimethylamine; C19H24N2OS;60-99-1; ̈ IMMOBILON*�Levomepromazine Hydrochloride / Methotrimeprazine Hydrochloride4185-80-2; NOZINAN
�Levomepromazine Maleate / Methotrimeprazine MaleateAntipsychotic
N
S
NMe2H Me
OMe
Levomethorphan lë·vö·me·thor·fan(-)-3-Methoxy-9a-methylmorphinan; C18H25NO; 125-70-2Antitussive
NMe
MeO
H
Levomoramide lë·vö·mo·ra·mïd(R)-1-(3-Methyl-4-morpholino-2,2-diphenylbutyryl)pyrrolidine; C25H32N2O2; 5666-11-5Opioid analgesic
NN
OO H Me
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3-18Levonantradol lë·vö·nan·tra·dol
(6S,6aR,9R,10aR)-5,6,6a,7,8,9,10,10a-Octahydro-9-hydroxy-6-methyl-3-[(1R)-1-methyl-4-phenylbutoxy]phenanthridin-1-yl acetate; C27H35NO4; 71048-87-8Levonantradol Hydrochloride 70222-86-5; CP-50556-1Antiemetic
NH
O
MeH
HOH
AcO
H Me
�Levonorgestrel lë·vö·nor·jes·trel(-)-13b-Ethyl-17b-hydroxy-18,19-dinor-17a-pregn-4-en-20-yn-3-one;D-norgestrel; d-norgestrel; C21H28O2; 797-63-7; CYCLO-PROGYNOVA*; EUGYNON*;LOGYNON*; MICROGYNON 30*; MICROVAL; MIRENA; NORGESTON; NORPLANT; NUVELLE;OVRAN*; OVRANETTE*; TRINORDIOL*Progestogen
O
H
H
H
H
EtCH
OH
Levophenacylmorphan lë·vö·fe·nä·sil·mor·fan2-[(-)-3-Hydroxymorphinan-9a-yl]acetophenone; C24H27NO2;10061-32-2Opioid analgesic
N
HO
H
O
Levopropoxyphene lë·vö·prö·poks·ë·fën(1R,2S)-1-Benzyl-3-dimethylamino-2-methyl-1-phenylpropyl propionate;C22H29NO2; 2338-37-6Antitussive
NMe2
OCH3
O
Ph
MeH
![Page 381: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/381.jpg)
3-19Levorphanol le·vor·fa·nol
(-)-9a-Methylmorphinan-3-ol; C17H23NO; 77-07-6Levorphanol Tartrate 125-72-4 (anhydrous); 5985-38-6 (dihydrate)Opioid analgesic
NMe
HO
H
Levothyroxine / Thyroxine lë·vö·thï·roks·ën/thï·roks·ënO4-(4-Hydroxy-3,5-di-iodophenyl)-3,5-di-iodo-L-tyrosine; C15H11I4NO4;51-48-9�Levothyroxine Sodium/Thyroxine Sodium 55-03-8; ELTROXIN; ¨ SOLOXINE
Thyroid hormone
O
I
I
I
HO COOH
H NH2
I
Lexipafant leks·i·pa·fantEthyl N-methyl-N-[a-(2-methylimidazo[4,5-c]pyridin-1-yl)tosyl]-L-leucinate;C23H30N4O4S; 139133-26-9; BB-882Platelet activating factor antagonist
N N
NMe
S
OO
NMeMe2HC
H
COOEt
Liarozole lï·a·rö·zôl(±)-5-(3-Chloro-a-imidazol-1-ylbenzyl)benzimidazole; C17Hl3ClN4;115575-11-6Liarozole Hydrochloride R75251Aromatase (testosterone) inhibitor
and enantiomer
N
N
H
Cl
N
N
H
![Page 382: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/382.jpg)
3-20�Lidocaine / Lignocaine lï·do·kän
2-Diethylaminoaceto-2¢,6¢-xylidide; C14H22N2O; 137-58-6�Lidocaine Hydrochloride / Lignocaine Hydrochloride 73-78-9 (anhydrous);6108-05-0 (monohydrate); BETNOVATE RECTAL*; BRADOSOL PLUS*; CALGEL*; EMLA*;HEMOCANE*; INSTILLAGEL*; ̈ LIGNAVET*; LIGNODREN*; ̈ LIGNOL*; LIGNOSTAB; ̈ LOCAIN*;¨LOCOVETIC*; MIN-I-JET LIGNOCAINE; ̈ NOPAINE*; XYLOCAINE; XYLOCARD; XYLOPROCT*;XYLOTOX*Local anaesthetic; antiarrhythmic
HN
NEt2
Me
MeO
Lidoflazine lï·dö·flä·zën4-[3-(4,4¢-Difluorobenzhydryl)propyl]piperazin-1-ylaceto-2¢,6¢-xylidide;C30H35F2N3O; 3416-26-0Vasodilator
N
NN
F
F
O
Me
Me
H
Lifarizine lï·fa·ri·zën1-Benzhydryl-4-(5-methyl-2-p-tolylimidazol-4-ylmethyl)piperazine; C29H32N4;119514-66-8; RS-87476-000Cerebral anti-ischaemic
N
N N
NMe
MeH
Lignocaine see Lidocaine
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3-21Lincomycin lin·kö·mi·sin
An antibiotic produced by Streptomyces lincolnensis var. lincolnensis;methyl 6-amino-6,8-dideoxy-N-[(2S,4R)-1-methyl-4-propylprolyl]-1-thio-a-D-erythro-D-galacto-octopyranoside; C18H34N2O6S; 154-21-2�Lincomycin Hydrochloride 859-18-7 (anhydrous); 7179-49-9(hydrate); ̈ LINCOCIN; LIMCOMIX; ̈ LINCO-SPECTIN*Antibiotic
N
H
H
Me
Prn
OHOHO
SMeOH
CH3
HHO
HCOHN
�Lindane lin·dän1a,2a,3b,4a,5a,6b-Hexachlorocyclohexane; gamma benzene hexachloride;C6H6Cl6; 58-89-9; ¨PARASITIC; QUELLADA; present in many veterinary preparationsTreatment of arthropod infection
Cl Cl
Cl Cl
Cl Cl
Linezolid li·nez·o·lidN-{[(S)-3-(3-Fluoro-4-morpholinophenyl)-2-oxo-1,3-oxazolidin-5-yl]methyl}acetamide; C16H20FN3O4; 165800-03-3; U-100,766
Antibacterial
N
O
FN
O O
AcHNH
Liothyronine lï·ö·thï·rö·nën4-O-(4-Hydroxy-3-iodophenyl)-3,5-di-iodo-L-tyrosine; (-)-tri-iodothyronine;C15H12I3NO4; 6893-02-3�Liothyronine Sodium 55-06-1; TERTROXIN
Thyroid hormone
O
I
I
HO COOH
H NH2
I
![Page 384: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/384.jpg)
3-22�Lisinopril lï·si·nö·pril
N-{N-[(S)-1-Carboxy-3-phenylpropyl]-L-lysyl}L-proline; C21H31N3O5; 76547-98-3;CARACE; ZESTORETIC*; ZESTRIL
Angiotensin-converting enzyme inhibitor
HN
O COOHH
NH
HOOC
NH2
H
Lisuride (lysuride) lï·sûr·rïd8-Decarboxamido-8-(3,3-diethylureido)-D-lysergamide; C20H26N4O; 18016-80-3Lisuride Maleate REVANIL
Dopamine receptor agonist
N
HN
Me
N NEt2
O
H
H
Liver Extract (BAN)Extract of mammalian (usually pig) liver containing small amounts ofcyanocobalamin, folic acid and, possibly, other haemopoietic factors; present inmany preparations
Lodoxamide lö·doks·a·mïdN,N¢-(2-Chloro-5-cyano-m-phenylene)dioxamic acid; C11H16ClN3O6;53882-12-5Lodoxamide Trometamol lodoxamide tromethamine (USAN);63610-09-3; ALOMIDE
Prophylaxis of allergic conditions
HN COOH
N COOH
O
OCl
NCH
Lofendazam lö·fen·da·zam8-Chloro-1,3,4,5-tetrahydro-1-phenyl-1,5-benzodiazepin-2-one; C15H13ClN2O;29176-29-2Tranquilliser
N
N
ClO
H
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3-23Lofentanil lö·fen·ta·nil
Methyl (3R,4S)-3-methyl-1-phenethyl-4-(N-phenylpropionamido)piperidine-4-carboxylate; C25H32N2O3; 61380-40-3Lofentanil Oxalate 61380-41-4; R 34995Opioid analgesic
H3C
N
O
N
Me
COOMe
Lofepramine lö·fe·pra·mën5-{3-[N-(4-Chlorophenacyl)-N-methylamino]propyl}-10,11-dihydro-5H-dibenz[b,f]azepine; C26H27ClN2O; 23047-25-8Lofepramine Hydrochloride GAMANIL
Antidepressant
N
N
Me O
Cl
Lofexidine lö·feks·i·dën2-[1-(2,6-Dichlorophenoxy)ethyl]-2-imidazoline; C11H12Cl2N2O;31036-80-3Lofexidine Hydrochloride BRITLOFEX
Alpha-adrenoceptor agonist
O
N
N
Cl
Cl
H MeH
and enantiomer
Lombazole lom·ba·zôl1-(a-Biphenyl-4-yl-2-chlorobenzyl)imidazole; C22H17ClN2; 60628-98-0;BAY h 6020Antimicrobial preservative
N
N
Cl
H
and enantiomer
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3-24Lomefloxacin lö·me·floks·a·sin
(RS)-1-Ethyl-6,8-difluoro-1,4-dihydro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid; C17H19F2N3O3; 98079-51-7; SC-47111AAntibacterial
HN
N N
F
F
O
COOH
Et
Me
H
and enantiomer
Lometrexol lö·me·treks·ol(R)-N-{4-[2-(2-Amino-3,4,5,6,7,8-hexahydro-4-oxopyrido[2,3-d]pyrimidin-6-yl)ethyl]benzoyl}-L-glutamic acid; C21H25N5O6; 106400-81-1Lometrexol Sodium 120408-07-3 (2Na); LY264618Antineoplastic
HN
N N
NHHOOC
H2N
O O
H COOH
H
H
�Lomustine lö·mus·tën1-(2-Chloroethyl)-3-cyclohexyl-l-nitrosourea; C9H16ClN3O2; 13010-47-4; CCNU
Cytotoxic
N NCl
O
NOH
Lonidamine lo·ni·da·mën1-(2,4-Dichlorobenzyl)indazole-3-carboxylic acid; Cl5H10Cl2N2O2;50264-69-2; AF 1890Antineoplastic
N
NCl
COOH
Cl
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3-25Loperamide lö·pe·ra·mïd
4-(4-p-Chlorophenyl-4-hydroxypiperidino)-N,N-dimethyl-2,2-diphenylbutyramide;C29H33ClN2O2; 53179-11-6�Loperamide Hydrochloride 34552-83-5; ARRET; ̈ DIAREZE; ̈ DIOCALM ULTRA;IMODIUM; LOPERAGEN; NORIMODE
Antidiarrhoeal
NNMe2
Ph Ph
OH
Cl
O
Loperamide Oxidetrans-4-(4-p-Chlorophenyl-4-hydroxypiperidino)-N,N-dimethyl-2,2-diphenylbutyramide N 4-oxide; C29H33ClN2O3; 106900-12-3; R58425Antidiarrhoeal
NNMe2
Ph Ph
OH
Cl
O
O
Lopinavir lö·pin·a·veer(S)-N-{(1S,3S,4S)-1-Benzyl-4-[2-(2,6-dimethylphenoxy)acetamido]-3-hydroxy-5-phenylpentyl}-3-methyl-2-(2-oxohexahydro-(2H)pyrimidin-1-yl)butanamide;C37H48N4O5;192725-17-0Antiviral
NH
N
OO
HN N
H
O
H H OH
H O Me
Me
H Pr i
Loprazolam lö·prä·zö·lam(Z)-6-(2-Chlorophenyl)-2,4-dihydro-2-(4-methylpiperazin-1-ylmethylene)-8-nitroimidazo[1,2-a][1,4]benzodiazepin-1-one; C23H21ClN6O3;61197-73-7�Loprazolam Mesilate 70111-54-5Hypnotic
N
N
N
N
NMeO2N
Cl
OH
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3-26Loracarbef lor·ra·kar·bef
(6R,7S)-3-Chloro-8-oxo-7-D-phenylglycylamino-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid; C16H16ClN3O4; 76470-66-1; LY163892Antibacterial
NH
NO
H2N H
O
H H
COOH
Cl
Loratadine lor·rat·a·dënEthyl 4-(8-chloro-5,6-dihydro-11H-benzo[5,6]cyclohepta[1,2-b]pyridin-11-ylidene)piperidine-1-carboxylate; C22H23ClN2O2; 79794-75-5; CLARITYN
Histamine H1-receptor antagonist
N
N
Cl
COOEt
�Lorazepam lor·rä·ze·pam7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-1,4-benzodiazepin-2-one;C15H10Cl2N2O2; 846-49-1; ATIVAN
Anxiolytic
N
NCl
O
Cl
OHH
and enantiomer
H
Lorcainide lor·kä·nïd4¢-Chloro-N-(1-isopropyl-4-piperidyl)-2-phenylacetanilide; C22H27ClN2O; 59729-31-6Lorcainide Hydrochloride 58934-46-6; R 15889Antiarrhythmic
N
O
N
Pr i
Cl
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3-27Lorcinadol lor·sin·a·dol
(E)-3-Chloro-6-(4-cinnamylpiperazin-1-yl)pyridazine; C17H19ClN4;104719-71-3; R62818Analgesic
N
NN
N
Cl
Loreclezole lor·re·kle·zôl(Z)-1-(b,2,4-Trichlorostyryl)-1H-1,2,4-triazole; C10H6Cl3N3;117857-45-1; R 72063Anticonvulsant
N
N
N
ClClCl
�Lormetazepam lor·me·tä·ze·pam7-Chloro-5-(2-chlorophenyl)-1,3-dihydro-3-hydroxy-l-methyl-1,4-benzodiazepin-2-one; C16H12Cl2N2O2; 848-75-9; NOCTAMID
Hypnotic; anxiolytic
N
NCl
O
OHH
Cl
Me
and enantiomer
Lornoxicam lor·noks·i·kam6-Chloro-4-hydroxy-2-methyl-N-2-pyridyl-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide; C13H10ClN3O4S2; 70374-39-9; Ro-13-9297Analgesic; anti-inflammatory
NMe
S N
NOH
Cl
O
SOO
H
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3-28Losartan lö·sar·tan
(2-Butyl-4-chloro-1-{4-[2-(2H-tetrazol-5-yl)phenyl]benzyl}-1H-imidazol-5-yl)methanol; C22H23ClN6O; 114798-26-4Losartan Potassium 124750-99-8; COZAAR
Antihypertensive; angiotensin-II receptor antagonist
N
HN
NN
Bun
N
NCl
HO
Losoxantrone lö·soks·an·trön7-Hydroxy-2-[2-(2-hydroxyethylamino)ethyl]-5-[2-(2-hydroxyethylamino)-ethylamino]naphtho[1,2,3-cd]indazol-6(2H)-one; C22H27N5O4; 88303-61-1; DUP941; NSC 357885; BIANTRAZOLE
Antineoplastic
NN
OOH HNN
OH
NOH
H
H
Loteprednol lö·të·pred·nolChloromethyl 11b,17a-dihydroxy-3-oxoandrosta-1,4-diene-17b-carboxylate;C21H27ClO5; 129260-79-3Loteprednol Etabonate (ester at O17); 82034-46-6; P-5604Corticosteroid
O
Me
H H
H
MeHO
OO
OH
Cl
Lovastatin lo·va·sta·tin(3R,5R)-7-{(1S,2S,6R,8S,8aR)-{1,2,6,7,8,8a-Hexahydro-2,6-dimethyl-8-[(S)-2-methylbutyryloxy]-1-naphthyl}3-hydroxyheptan-5-olide; mevinolin; C24H36O5;75330-75-5; MK-803; L-154,803Hypolipidaemic
H
O
HO
O
MeH3C
Me
Me
H
OHO
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3-29Loviride lö·vi·rïd
N2-(6-acetyl-m-tolyl)-DL-2-(2,6-dichlorophenyl)glycinamide; C17H16Cl2N2O2;147362-57-0; R 89439Inhibitor of HIV replication in vitro; antiviral
N
H2N O
H
CH3O
Me
Cl
Cl
H
and enantiomer
Loxapine loks·a·pën2-Chloro-11-(4-methylpiperazin-1-yl)dibenz[b,f][1,4]oxazepine; C18H18ClN3O;1977-10-2; LOXAPAC
Antipsychotic
N
O
Cl
N
NMe
Lubeluzole loo·be·lü·zôl(S)-1-{4-[1,3-benzothiazol-2-yl(methyl)amino]piperidino}-3-(3,4-difluorophenoxy)propan-2-ol; C22H25F2N3O2S;144665-07-6;R 87926Neural protective agent; anti-stroke
S
NN
NO
F
F
H OH
Me
Lucanthone loo·kan·thön1-(2-Diethylaminoethylamino)-4-methylthioxanthen-9-one; C20H24N2OS; 479-50-5Lucanthone Hydrochloride 548-57-2Anthelmintic
S
O
Me
NNEt2
H
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3-30Lufenuron loo·fen·ûr·ron
(RS)-N-[2,5-Dichloro-4-(1,1,2,3,3,3-hexafluoropropoxy)phenylcarbamoyl]-2,6-difluorobenzamide; C17H8Cl2F8N2O3; 103055-07-8; ̈ PROGRAM
Insecticide; inhibitor of chitin synthesis
HH
and enantiomer
CF3F F
O
Cl
Cl
F
F OO
NN
H F
Lumefantrine loo·me·fan·trën(1RS)-2-(Dibutylamino)-1-{2,7-dichloro-9-[(Z)-4-chlorobenzylidene]fluoren-4-yl}ethanol; C30H32Cl3NO; 82186-77-4Antimalarial
NBu2
Cl Cl
Cl
HO
H
H
and enantiomer
Luprostiol loo·prost·ë·ol(1) (±)-(Z)-7-{(1S,2R,3R,5S)-2-[(2S)-3-(3-Chlorophenoxy)-2-hydroxy-propylthio]-3,5-dihydroxycyclopentyl}hept-5-enoic acid; (2) (±)-(5Z)-(9S,11R,15S)-16-(3-chlorophenoxy-9,11,15-trihydroxy-w-tetranor-13-thiaprost-5-enoic acid; C21H29ClO6S; 67110-79-6; ̈ PROSOLVIN
Prostanoid luteolytic (veterinary)
S O
H
H OHHHO
COOH
Cl
HO
and enantiomer
Lurosetron lûr·rö·së·tron6-Fluoro-2,3,4,5-tetrahydro-5-methyl-2-(5-methylimidazol-4-ylmethyl)pyrido[4,3-b]indol-1-one; C17H17FN4O; 128486-54-4; GR 87442XLurosetron Mesilate 143486-90-2; GR 87442NSerotonin 5HT3-receptor antagonist
N
N
F
NN
Me
MeO
H
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3-31Lutropin Alfa loo·trö·pin al·fa
Luteinising hormone (human a-subunit reduced complex human b-subunitreduced), glycoform a;a-subunit: C437H682N122O134S13; b-subunit: C577H929N165O161S14; 56832-30-5Stimulation of follicle maturation; treatment of infertilty Ares-Serono
Luxabendazole luks·a·ben·da·zôlMethyl 5-(4-fluorophenylsulfonyloxy)benzimidazol-2-ylcarbamate; C15H12FN3O5S;90509-02-7; HOE 216VAnthelmintic
ON
N NHCOOMe
SOO
F
H
�Lymecycline lï·më·sï·klënA water-soluble combination of tetracycline, lysine and formaldehyde;C29H38N4O10; 992-21-2; TETRALYSAL
Antibacterial
OH O HO O
OH
NMe2HH
MeHO
OH
N N COOH
O H NH2
H H
�Lynestrenol (lynoestrenol) lï·nës·tre·nol19-Nor-17a-pregn-4-en-20-yn-17b-ol; C20H28O; 52-76-6; MINILYN*Progestogen
H
H
H
H
Me OH
CH
Lypressin lï·pres·sin[8-Lysine]vasopressin; C46H65N13O12S; 50-57-7; SYNTOPRESSIN
Antidiuretic hormone
Cys-Tyr-Phe-Gln-Asn-Cys-Pro-Lys-Gly-NH2
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3-32�Lysergide
N,N-Diethyl-D-lysergamide; lysergic acid diethylamide; LSD; C20H25N3O; 50-37-3
N
HN
MeH
CONEt2H
Lysuride see Lisuride
�Macrogol ma·krö·golPolyethylene glycol of general formula H-(OCH2CH2)n-OH where n varies from 3to 225 approximately. Each macrogol name is followed by a number correspondingapproximately to its average molecular weight, eg macrogol 300, 400, 1000, 4000;9002-90-8; KLEAN-PREP*; MOVICOL*Pharmaceutical aid
CH2O CH2 OHH n
Macrogol 8 Stearate (polyoxyl 8 stearate)Polyoxyethylene 8 stearate; MYRJ 45Non-ionic surfactant
Macrogol 40 Stearate (polyoxyl 40 stearate)Polyoxyethylene 40 stearate; MYRJ 52; MYRJ 52S
Non-ionic surfactant
Macrosalb(131I) ma·krö·salbMacroaggregated iodinated (131I) human albumin; 54182-63-7Diagnostic aid to examination of pulmonary perfusion
Macrosalb(99mTc) ma·krö·salbTechnetium(99mTc)-labelled macroaggregated human albumin;54277-47-3Diagnostic aid to examination of pulmonary perfusion
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3-33Maduramicin ma·dûr·ra·mï·sin
Ammonium (2R,3S,4S,5R,6S)-tetrahydro-2-hydroxy-6-{(R)-1-[(2S,5R,7S,8R,9S)-9-hydroxy-2,8-dimethyl-2-{(2S,2¢R,3¢S,5R,5¢R)-octahydro-2-methyl-3¢-[(2R,4S,5S,6S)-tetrahydro-4,5-dimethoxy-6-methyl-2H-pyran-2-yloxy]-5¢-[(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl]2,2¢-bifuran-5-yl}-1,6-dioxaspiro[4,5]dec-7-yl]ethyl}-4,5-dimethoxy-3-methyl-2H-pyran-2-acetate; C47H83NO17; 84878-61-5Anticoccidial (veterinary)
NH4+
OMe
OMe
MeOO
OO O
O
O
HO
Me Me
MeO
OMe
Me
COO_
Me
OH
OMe
Me Me
OH
H
MeHH
H
H
H
Mafenide ma·fen·ïda-Aminotoluene-p-sulfonamide; C7H10N2O2S; 138-39-6Mafenide Acetate 13009-99-9Antibacterial
H2N
SO2NH2
�Magaldrate mag·al·drätA synthetic combination of aluminium and magnesium hydroxides and sulfuric acidcorresponding approximately to the formula Al5Mg10(OH)31(SO4)2,xH2O; 74978-16-8; AY-5710; DYNESE
Antacid
�Malathion (BAN) mal·a·thï·onDiethyl 2-(dimethoxyphosphinothioylthio)succinate; C10H19O6PS2;121-75-5; DERBAC-M; PRIODERM; SULEO-M
Insecticide
MeO P
S
OMe
S
COOEt
COOEt
H
and enantiomer
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3-34�Maletamer (malethamer)
High molecular weight copolymer of ethylene and maleic anhydride cross-linkedwith 1 to 2% w/w of vinyl crotonate; 9006-26-2
OO On
Maltitol (BAN) mál·ti·tolD-Glucopyranosyl-D-glucitol; C12H24O11 ; 585-88-6Sweetening agent
OHH
HHO
H
H OH
OH
OH
O
HO
OH
OH
O
HO
Mangafodipir man·ga·fö·di·peerHexahydrogen (OC-6-13)-N,N¢-ethane-1,2-diylbis{N-[2-methyl-3-oxido-kO-5-(phosphonatooxymethyl)-4-pyridylmethyl]glycinato(O,N)}manganate(II);C22H30MnN4O14P2; 155319-91-8; WIN 59010-2; S-095; MnDPDPMangafodipir Trisodium 140678-14-4Paramagnetic contrast medium for diagnostic magnetic resonance imaging
Mn
NO
N N
NO
O
O
O
OP
OO
OP
OO
MeMe
O O
O6H+ +2
_
__
_
_
_
_
_6
_
Mannomustine man·ö·mus·tën1,6-Bis(2-chloroethylamino)-1,6-dideoxy-D-mannitol; C10H22Cl2N2O4;576-68-1Cytotoxic
ClN
NCl
OH
OH
OH
OH
H
H
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3-35Maprotiline ma·prö·ti·lën
3-(9,10-Dihydro-9,10-ethanoanthracen-9-yl)propyl(methyl)amine; C20H23N;10262-69-8Maprotiline Hydrochloride 10347-81-6; LUDIOMIL
Antidepressant
NHMe
Marbofloxacin mar·bö·floks·a·sin9-Fluoro-2,3-dihydro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-7H-pyrido[3,2,1-ij][4,1,2]benzoxadiazine-6-carboxylic acid; C17H19FN4O4; 115550-35-1; ̈ MARBOCYL
Antibacterial
NN N
F COOH
O
O NMeMe
Maribavir ma·rib·a·veer5,6-Dichloro-2-(isopropylamino)-1-(b-L-ribofuranosyl)benzimidazole;C15H19Cl2N3O4; 176161-24-3; 1263W94
AntiviralCl
Cl
N
NNHPri
O
OHOH
OH
Marimastat ma·ri·ma·stat(2S,3R)-3-{(S)-[2,2-Dimethyl-1-(methylcarbamoyl)propyl]carbamoyl}-2-hydroxy-5-methylhexanohydroxamic acid; C15H29N3O5; 154039-60-8; BB-2516Inhibitor of matrix metalloproteinases
Me
Me
O NH
CONHOH
H
CONHMe
HMe
MeMe
OHH
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3-36�Mazindol maz·in·dol
(RS)-5-(4-Chlorophenyl)-2,5-dihydro-3H-imidazo[2,1-a]isoindol-5-ol;C16H13ClN2O; 22232-71-9Appetite suppressant
N
N
HO
Cl
and enantiomer
Mazokalim ma·zo·ka·limEthyl (3S,4R)-4-{5-[3-hydroxy-2,2,3-trimethyl-4-(1,6-dihydro-6-oxopyridazin-3-yloxy)chroman-6-yl]tetrazol-1-yl}butyrate; C23H28N6O6; 164178-54-5; UK-143,220Potassium channel opener; bronchodialtor
O
Me
NONH
O
OHNN
NN
MeMe
EtOOC
Mebanazine me·ban·a·zëna-Methylbenzylhydrazine; C8H12N2; 65-64-5Monoamine oxidase inhibitor
NNH2
H Me
H
and enantiomer
�Mebendazole me·ben·da·zôlMethyl 5-benzoylbenzimidazol-2-ylcarbamate; C16H13N3O3; 31431-39-7;¨CHANAZOLE; ̈ EQUIVURM PLUS; OVEX; ̈ OVITELMIN; ̈ SUPAVERM* ̈ TELMIN; VERMOX
Anthelmintic
O
NH
NH
NH
OMe
O
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3-37Mebeverine me·bev·er·rën
(RS)-4-[Ethyl(4-methoxy-a-methylphenethyl)amino]butyl veratrate; C25H35NO5;3625-06-7�Mebeverine Hydrochloride 2753-45-9; COLOFAC; FYBOGEL MEBEVERINE
Mebeverine Pamoate COLOFAC LIQUID
Antispasmodic
O
N
O
Et
MeMeO
MeO
OMe
and enantiomer
�Mebezonium Iodide4,4¢-Methylenebis(cyclohexyltrimethylammonium) di-iodide; C19H40I2N2; 7681-78-9
Me3N NMe3
2I+ +_
�Mebhydrolin meb·hï·drö·lin5-Benzyl-1,2,3,4-tetrahydro-2-methyl-g-carboline; C19H20N2; 524-81-2Mebhydrolin Napadisilate 6153-33-9Histamine H1-receptor antagonist
N
NMe
Mebrofenin me·brö·fe·nin({[(3-Bromomesityl)carbamoyl]methyl}imino)diacetic acid; C15H19BrN2O5; 78266-06-5; SQ26962Diagnostic aid
NN
Me
Br
Me
Me COOH
COOH
O
H
Mebutamate me·bü·ta·mät2-sec-Butyl-2-methyltrimethylene dicarbamate; C10H20N2O4; 64-55-1Sedative
H2N O O NH2
O
CH3H3C
Me
O
H
mixture of stereoisomers
*
*
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3-38Mecamylamine me·ka·mïl·a·men
(1R,2R,4S)-Methyl(2,3,3-trimethylbicyclo[2.2.1]hept-2-yl)amine; C11H21N; 60-40-2Mecamylamine Hydrochloride 826-39-1Ganglion blocker
Me
MeMe
NHMe
Mecasermin me·ka·ser·minInsulin-like growth factor I (human); C331H512N94O101S7; 67763-96-6; 68562-41-4Growth factor Mecasermin has the following amino acid sequence:
GPETLCGAEL VDALQFVCGD RGFYFNKPTG
YGSSSRRAPQ TGIVDECCFR SCDLRRLEMY
CAPLKPAKSA
Mecetronium Etilsulfate me·se·trö·në·umEthyl(hexadecyl)dimethylammonium ethyl sulfate; C22H49NO4S; 3006-10-8Antiseptic
EtSO4NMe2
Et
H3C[ CH2] 14CH2+ _
�Mecillinam me·si·li·nam(6R)-6-(Perhydroazepin-1-ylmethyleneamino)penicillanic acid; C15H23N3O3S;32887-01-7Antibacterial
NO
S
H COOH
Me
Me
H H
NN
Meclocycline me·klö·sï·klën(1) (4S,4aR,5S,5aR,12aS)-7-Chloro-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxonaphthacene-2-carboxamide; (2) 7-chloro-6-demethyl-6-deoxy-5b-hydroxy-6-methylenetetracycline; C22H21ClN2O8; 2013-58-3 GS 2989; NSC 78502Antibacterial
OH O HO O
CONH2
OH
NMe2HH
OH
CH2 OHCl
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3-39�Meclofenamic Acid me·klö·fe·nam·ik
N-(2,6-Dichloro-m-tolyl)anthranilic acid; C14H11Cl2NO2; 644-62-2; ̈ ARQUEL
Analgesic; anti-inflammatory
N
COOH
Cl
Cl
Me
H
Meclofenoxate2-Dimethylaminoethyl 4-chlorophenoxyacetate; C122H16ClNO3; 51-68-3Central nervous system stimulant
OO
NMe2
Cl
O
Meclorisone me·klor·i·sön9,11b-Dichloro-17a,21-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione;C22H28Cl2O4; 4732-48-3Meclorisone Butyrate 10549-91-4; Sch 11572Corticosteroid
O
Me H
Me
Cl H
Cl
Me
O
OH
OH
Meclozine me·klö·zën(RS)-1-(4-Chlorobenzhydryl)-4-(3-methylbenzyl)piperazine; C25H27ClN2; 569-65-3�Meclozine Hydrochloride meclizine hydrochloride (USAN);1104-22-9 (anhydrous); 31884-77-2 (hydrate); SEA LEGS
Histamine H1-receptor antagonist
and enantiomer
N
N
Cl
HMe
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3-40Mecobalamin me·kö·ba·la·min
Coa-[a-(5,6-Dimethylbenzimidazolyl)-Cob-methylcobamide; C63H91CoN13O14P;13422-55-4Vitamin B12 analogue
Me
H2N
OMe
H2N
O
H
Me
OO
HO
H
OHHHP
O
O_
ONH H Me
O O
HNH2
Me
Me
MeMe
O
H2N
Me
O
NH2 O
NH2
Me
N
N
Co
N
N
N
N Me
Me
H
H
H
H
+
Mecysteine (methyl cysteine) me·sis·tänL-Cysteine methyl ester; C4H9NO2S; 2485-62-3Mecysteine Hydrochloride 5714-80-7; VISCLAIR
Mucolytic
HSCOOMe
H NH2
Medazepam me·dä·ze·pam7-Chloro-2,3-dihydro-1-methyl-5-phenyl-1H-1,4-benzodiazepine; C16H15ClN2;2898-12-6Anxiolytic
N
NCl
Me
Medetomidine me·de·to·mi·dën(±)-4-[1-(2,3-Xylyl)ethyl]imidazole; C13H16N2; 86347-14-0; ̈ DOMITOR
Sedative; analgesic (veterinary)
N
N
Me
MeMeH
Hand enatiomer
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3-41Medigoxin me·di·joks·in
3b-[O-(2,6-Dideoxy-4-O-methyl-D-ribo-hexopyranosyl)-(1® 4)-O-(2,6-dideoxy-D-ribo-hexopyranosyl)-(1® 4)-2,6-dideoxy-D-ribo-hexopyranosyloxy]-12b,14-dihydroxy-5b,14b-card-20(22)-enolide; metildigoxin (pINN); C42H66O14; 30685-43-9Treatment of cardiac insufficiency
R =Me
H
H
H
OH
MeOH
OO
R
2
O
OH
Me
MeO
O
OH
Me O
O
Medrogestone me·drö·jes·tön6,17a-Dimethylpregna-4,6-diene-3,20-dione; C23H32O2; 977-79-7 AY-62022; R-13-615Progestogen
O
Me
H H
HMe
MeMe
CH3O
Medronic Acid me·dron·ikMethylenebis(phosphonic acid); CH6O6P2; 1984-15-2Disodium Medronate 25681-89-4; AMERSCAN*Diagnostic aid
P
O
OH
OHP
O
OH
HO CH2
Medroxalol me·droks·a·lol5-{2-[3-(1,3-Benzodioxol-5-yl)-1-methylpropylamino]-1-hydroxy-ethyl}salicylamide; C20H24N2O5; 56290-94-9Medroxalol Hydrochloride 70161-10-3; RMI 81968AAlpha- and beta-adrenoceptor antagonist
NH OH
H Me
O
OH2NOC
HO
H
mixture of stereoisomers
* *
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3-42Medroxyprogesterone me·droks·ë·prö·jes·te·rön
17a-Hydroxy-6a-methylpregn-4-ene-3,20-dione; C22H32O3; 520-85-4�Medroxyprogesterone Acetate 71-58-9; DEPO-PROVERA; FARLUTAL; IMPROVERA*;¨PERLUTEX; PREMIQUE CYCLE*; ̈ PROMONE-E; PROVERA; TRIDESTRA*; ̈ VERAMIX
Progestogen
O
Me
Me
H
H H
Me
O Me
OH
�Mefenamic Acid me·fen·a·mikN-2,3-Xylylanthranilic acid; C15H15NO2; 61-68-7; MEFLAM; PONSTAN
Analgesic; anti-inflammatory
NH
Me
Me
COOH
Mefloquine me·flö·kwën(RS)-2,8-Bis(trifluoromethyl)-4-quinolyl[(SR)-2-piperidyl]methanol; C17H16F6N2O;53230-10-7; Ro 21-5998Mefloquine Hydrochloride 51773-92-3; LARIAM
Antimalarial
H
H
N
NHO
CF3
CF3
H
and enantiomer
Mefruside me·froo·sïd4-Chloro-N1-methyl-N1-(2-methyltetrahydrofurfuryl)benzene-1,3-disulfonamide;C13H19ClN2O5S2; 7195-27-9; BAYCARON
Diuretic
N
O OS
Cl
NH2S
OO
Me
OMe
and enantiomer
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3-43Megestrol me·jes·trol
17a-Hydroxy-6-methylpregna-4,6-diene-3,20-dione; C22H30O3; 3562-63-8�Megestrol Acetate 595-33-5; MEGACE; ¨OVARID
Progestogen
O
Me
H
OAcMe
Me
Me
H
O
�Meglumine meg·loo·mën1-Methylamino-1-deoxy-D-glucitol; C7H17NO5; 6284-40-8Diagnostic aid
OHH
HHO
H OH
H OH
NHMe
OH
Meladrazine me·la·dra·zënTetraethyl(6-hydrazinotriazin-2,4-diyl)diamine; C11H23N7; 13957-36-3Muscle relaxant
N N
NHN
NH2Et2N
NEt2
Melarsonyl Potassium me·lar ·sö·nilDipotassium 2-[4-(4,6-diamino-1,3,5-triazin-2-ylamino)phenyl]-1,3,2-dithiarsolan-4,5-dicarboxylate; C13H11AsK2N6O4S2; 13355-55-0Antiprotozoan
N
N
N
N
As S
SNH2
H2N
COOK
COOK
H
Melarsoprol me·lar ·sö·prol2-[4-(4,6-Diamino-1,3,5-triazin-2-ylamino)phenyl]-1,3,2-dithiarsolan-4-ylmethanol; C12H15AsN6OS2; 494-79-1Antiprotozoan
N
N
N
N
As S
SNH2
H2N
CH2OH
H
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3-44Melengestrol me·len·jes·trol
17a-Hydroxy-6-methyl-16-methylenepregna-4,6-diene-3,20-dione; C23H30O3; 5633-18-1Progestogen
O
Me
H H
HMe
MeOH
CH3O
CH2
�Meloxicam me·loks·i·kam4-Hydroxy-2-methyl-N-(5-methyl-1,3-thiazol-2-yl)-2H-1,2-benzothiazine-3-carboxamide 1,1-dioxide; C14H13N3O4S2; 71125-38-7; ̈ METACAM; MOBIC
Analgesic; anti-inflammatory
N
N
OOH
MeSOO
S
N
Me
H
Melperone mel·pe·rön4¢-Fluoro-4-(4-methylpiperidino)butyrophenone; C16H22FNO; 3575-80-2Melperone Hydrochloride 1622-79-3; FG 5111Antipsychotic
N
F
OMe
�Melphalan mel·fa·lan4-Bis(2-chloroethyl)amino-L-phenylalanine; C13H18Cl2N2O2; 148-82-3; ALKERAN
Cytotoxic
COOH
N
Cl
Cl H NH2
�Menadiol (BAN) me·na·dï·ol2-Methylnaphthalene-1,4-diol; C11H10O2; 481-85-6Vitamin K analogue
Me
OH
OH
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3-45Menadiol Potassium Sulfate (potassium menaphthosulphate) me·na·dï·ol
Dipotassium 2-methylnaphthalene-1,4-disulfonate; C11H8K2O8S2; 1612-30-2Vitamin K analogue
Me
OSO3K
OSO3K
�Menadione (BAN) me·na·dï·ön2-Methyl-1,4-naphthoquinone; C11H8O2; 58-27-5Vitamin K analogue
O
O
Me
Menadoxime (BAN) me·na·doks·ëmAmmonium salt of 2-methylnaphthoquinone 4-oxime O-carboxymethyl ether;C13H14N2O4; 6146-99-2Treatment of hypoprothrombinaemia
O
N
Me
O COONH4
Menbutone men·bü·tön4-(4-Methoxy-1-naphthyl)-4-oxobutyric acid; C15H14O4; 3562-99-0Menbutone Diethanolamine ¨GENEBILE; ¨QUADRAMAX
Choleretic
OMe
COOHO
�Menotrophin (BAN) men·ö·trö·finA dry preparation containing glycoprotein gonadotrophins possessing follicle-stimulating and luteinising activities. It contains not less than 40 units of follicle-stimulating hormone activity per mg. The ratio of Units of luteinising hormone(LH) activity to Units of follicle-stimulating hormone (FSH) activity isapproximately 1. The preparation is exclusively or predominantly of pituitary originand is obtained from the urine of post-menopausal women but, where necessary,chorionic gonadotrophin obtained from the urine of pregnant women may beadded to achieve the above ratio; menotropins (USAN); 9002-68-0; MENOGON;PERGONAL
Follicle-stimulating hormoneSee also Human Menopausal Gonadotrophin, Follitropin Alfa and Follitropin Beta
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3-46Mepacrine me·pa·krën
6-Chloro-9-(4-diethylamino-1-methylbutylamino)-2-methoxyacridine;C23H30ClN3O; 83-89-6Mepacrine Hydrochloride 69-05-6 (2HCl); 6151-30-0 (2HCl, 2H2O)Antimalarial
N
OMe
Cl
HNNEt2
H Me
and enantiomer
Mepartricin me·par·tri·sinA mixture of the methyl esters of two related polyene macrolide antibiotics obtainedfrom a strain of Streptomyces aurofaciens or by any other means; 11121-32-70
O OH O OH OH OH
OH
O
O
Me
OH
O
COOMeOH
O
NHMe
Me
Me
HO
NH2
OHO
HO
mepartricin A
�Mepenzolate Bromide me·pen·zö·lät(RS)-3-Benziloyloxy-1,1-dimethylpiperidinium bromide; C21H26BrNO3;76-90-4Anticholinergic
ONMe2
HO
O
H Br_
+
and enantiomer
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3-47Mephenesin me·fen·ë·sin
(RS)-3-o-Tolyloxypropane-1,2-diol; C10H14O3; 59-47-2Sedative; tranquilliser
Me
O OHH OH
and enantiomer
�Mephenytoin (methoin)(RS)-5-Ethyl-3-methyl-5-phenylhydantoin; C12H14N2O2; 50-12-4
N
N O
O Me
H
Et
and enantiomer
Mephentermine me·fen·ter·mënN,a,a-Trimethylphenethylamine; C11H17N; 100-92-5Mephentermine Sulphate 1212-72-2Sympathomimetic
NHMe
Me Me
Mepindolol me·pin·do·lol(RS)-1-Isopropylamino-3-(2-methylindol-4-yloxy)propan-2-ol; C15H22N2O2; 23694-81-7Beta-adrenoceptor antagonist
HN
OHH
NHPr iO
Me
and enantiomer
Mepiprazole me·pip·ra·zôl1-(3-Chlorophenyl)-4-[2-(5-methyl-1H-pyrazol-3-yl)ethyl]piperazine; C16H21ClN4;20326-12-9Psychotropic
N
N Cl
NNMe
H
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3-48Mepivacaine me·pi·va·kän
1-Methyl-2-piperidylformo-2¢,6¢-xylidide; C15H22N2O; 96-88-8; ESTRADURIN*Mepivacaine Hydrochloride 1722-62-9; ̈ INTRA-EPICAINE
Local anaesthetic
NN
Me
Me OMe
H H
and enantiomer
�Meprobamate me·prö·ba·mät2-Methyl-2-propyltrimethylene dicarbamate; C9H18N2O4; 57-53-4; EQUAGESIC*;EQUANIL; MEPRATE
Sedative
H2N O
O
Me Prn
O
NH2O
Meprochol (BAN) me·prö·kol(2-Methoxyprop-2-enyl)trimethylammonium bromide; C7H16BrNO;590-31-8Cholinergic
H2CNMe3
OMe+
Br_
Meproscillarin me·prö·sil·a·rin14-Hydroxy-3b-(4-O-methyl-a-L-rhamnopyranosyloxy)-14b-bufa-4,20,22-trienolide; C31H44O8; 33396-37-1Cardiac glycoside
Me
H
H
OH
MeH
O
O
OO
OHOH
MeO
Me
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3-49Meprotixol (meprothixol) me·prö·tiks·ol
9-(3-Dimethylaminopropyl)-2-methoxythioxanthen-9-ol; C19H23NO2S;4295-63-0Analgesic; anti-inflammatory
and enantiomer
S
NMe2
OH
OMe
Meptazinol mep·ta·zi·nol3-(3-Ethyl-1-methylperhydroazepin-3-yl)phenol; C15H23NO; 54340-58-8�Meptazinol Hydrochloride 34154-59-1; MEPTID
Opioid analgesic
N
Me
EtOH
Mepyramine me·pï·ra·mën2-(N-p-Anisyl-N-2-pyridylamino)ethyldimethylamine; pyrilamine (USAN);C17H23N3O; 91-84-9�Mepyramine Maleate 59-33-6; ANTHISAN
Histamine H1-receptor antagonist
NNMe2
NMeO
Mequitazine me·kwi·ta·zën3-(Phenothiazin-10-ylmethyl)quinuclidine; C20H22N2S; 29216-28-2; PRIMALAN
Histamine H1-receptor antagonist
N
N
S
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3-50Meralluride mer·ral·lûr·rïd
A mixture of (RS)-3-[3-(3-carboxypropionyl)ureido]-2-methoxypropyl-hydroxomercury and theophylline; 8069-64-5Diuretic
N
NN
HN
O
O
Me
Me
HgHN
HN
O
MeO HCOOH
O
HO
.
and enantiomer
Mercaptamine (cysteamine) mer·kap·ta·mën2-Aminoethanethiol; C2H7NS; 60-23-1Antidote to paracetamol poisoning
SHH2N
Mercaptomerin (mercaptomerin sodium) mer·kap·tö·me·rinDisodium salt of carboxymethylthio[3-(3-carboxy-2,2,3-trimethyl-cyclopentanecarboxamido)-2-methoxypropyl]mercury; C16H25HgNNa2O6S; 20223-84-1Diuretic
Me MeMe
HOOCN Hg
O
OMeH
S COOH* *
*
mixture of stereoisomers
�Mercaptopurine mer·kap·tö·pûr·rënPurine-6-thiol; C5H4N4S; 50-44-2 (anhydrous); 6112-76-1 (monohydrate); PURI-NETHOL
Cytotoxic
N
N
N
N
SHH
Mercurophylline (mercurophylline sodium) mer·kûr·ro·fi·lënA mixture of theophylline and the sodium salt of [3-(3-carboxy-2,2,3-tri-methylcyclopentanecarboxamido)-2-methoxypropyl]hydroxomercury;8012-34-8Diuretic
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3-51Meropenem me·rö·pe·nem
(4R,5S,6S)-3-[(3S,5S)-5-Dimethylcarbamoylpyrrolidin-3-ylthio]-6-[(R)-1-hydroxyethyl]-4-methyl-7-oxo-1-azabicyclo[3.2.0]hept-2-ene-2-carboxylic acid;C17H25N3O5S; 96036-03-2; MERONEM
Antibacterial
NS
N
H
CONMe2
H
COOH
MeH
H3C
O
HHOHH
H
Mesalazine me·sal·a·zën5-Aminosalicylic acid; 5-ASA; C7H7NO3; 89-57-6; ASACOL; PENTASA; SALOFALK
Treatment of ulcerative colitis
COOH
OH
H2N
MesnaSodium 2-mercaptoethanesulfonate; C2H5NaO3S2; 19767-45-4; UROMITEXAN
Cytotoxic antagonist
HSSO3Na
Mesoridazine mez·ö·ri·da·zën(RS)-10-[2-(1-Methyl-2-piperidyl)ethyl]-2-(methylsulfinyl)phenothiazine;C21H26N2OS2; 5588-33-0Antipsychotic
NN
S
S
CH3
Me
O
H
and enantiomer
�Mestanolone17b-Hydroxy-17a-methyl-5a-androstan-3-one; C20H32O2; 521-11-9
OH
MeOH
MeMe
H
H H
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3-52Mesterolone me·ste·ro·lön
17b-Hydroxy-1a-methyl-5a-androstan-3-one; C20H32O2; 1424-00-6;PRO-VIRON
Androgen
OH
MeOH
HMe
H
H H
HMe
�Mestranol mes·tra·nol(1) 3-Methoxy-19-nor-17a-pregna-1,3,5(10)-trien-20-yn-17b-ol; (2)ethinyloestradiol 3-methyl ether; C21H26O2; 72-33-3; MENOPHASE*; NORINYL*; ORTHO-NOVIN*Oestrogen
MeO
H
H
H
MeCH
OH
Mesulphen më·sul·fen2,7-Dimethylthianthrene; mesulfen (pINN); C14H12S2; 135-58-0Treatment of skin infections
S
S
Me
Me
Mesuximide (methsuximide) me·suks·i·mïd(RS)-N,2-Dimethyl-2-phenylsuccinimide; C12H13NO2;77-41-8Anticonvulsant
N
Me
O
O
Me
and enantiomer
�Metacetamol3¢-Hydroxyacetanilide; C8H9NO2; 621-42-1
NHAc
OH
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3-53Metahexamide met·a·heks·a·mïd
1-(3-Amino-p-tolysulfonyl)-3-cyclohexylurea; C14H21N3O3S; 565-33-3Hypoglycaemic
HN N
O
SOO
H2N
MeH
Metallibure (methallibure) me·tal·i·bûr1-Methyl-6-(1-methylallyl)-2,5-dithiobiurea; C7H14N4S2; 926-93-2Suppression of hypothalamic and pituitary function
H2CN N
N NH Me S
S
CH3H H
H H
and enantiomer
Metamelfalan me·ta·mel·fa·lan3-[Bis(2-choroethyl)amino]-L-phenylalanine; C13H18ClN2O2; 1088-80-8Cytotoxic
NCl
Cl
COOH
H NH2
�Metamfazone (methamphazone)4-Amino-6-methyl-2-phenylpyridazin-3(2H)-one; C11H11N3O;54063-49-9
NN Me
NH2
O
Metaraminol met·a·ram·i·nol(1R,2S)-2-Amino-1-(3-hydroxyphenyl)propan-1-ol; C9H13NO2; 54-49-9�Metaraminol Tartrate 17171-57-2; ARAMINE
Sympathomimetic
CH3HOHO H
H NH2
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3-54Metaxalone me·taks·a·lön
(RS)-5-(3,5-Xylyloxymethyl)-2-oxazolidone; C12H15NO3; 1665-48-1Skeletal muscle relaxant
ONH
OMe
Me
O
H
and enantiomer
Metazocine me·tä·zö·sën(2R,6R,11R)-1,2,3,4,5,6-Hexahydro-3,6,11-trimethyl-2,6-methano-3-benzazocin-8-ol; C15H21NO; 3734-52-9Opioid analgesic
NMeMe
HO
Me H
Metenolone (methenolone) me·ten·o·lön17b-Hydroxy-1-methyl-5a-androst-1-en-3-one; C20H30O2; 153-00-4Metenolone Acetate 434-05-9Anabolic steroid; androgen
OH
H H
HMeMe
MeH
OAc
Metergoline me·ter·gö·lënBenzyl (8S,10R)-(1,6-dimethylergolin-8-ylmethyl)carbamate; C25H29N3O2; 17692-51-2Serotonin receptor antagonist
N
N
NH
OMe
Me
OH H
H
�Metetoin (methetoin)(RS)-5-Ethyl-1-methyl-5-phenylhydantoin; C12H14N2O2; 5969-06-0
NH
N
Me
O
O
Ph
Et
and enantiomer
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3-55Metformin met·for·min
1,1-Dimethylbiguanide; C4H11N5; 657-24-9�Metformin Hydrochloride 1115-70-4; GLUCOPHAGE; ORABET
Hypoglycaemic
NMe2NH
H2N
NHNH
Methacholine Chloride me·tha·kö·lën(1) Acetyl-b-methylcholine chloride; (2) (2-acetoxypropyl)trimethylammoniumchloride; C8H18ClNO2; 62-51-1Cholinergic
H3C ONMe3
O MeH +Cl
_
and enantiomer
Methacycline me·tha·sï·klen(1) 4S,4aR,5S,5aR,12aS)-4-Dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,10,12,12a-pentahydroxy-6-methylene-1,11-dioxonaphthacene-2-carboxamide;(2) 6-demethyl-6-deoxy-5b-hydroxy-6-methylenetetracycline; metacycline (pINN);C22H22N2O8; 914-00-1Methacycline Hydrochloride 3963-95-9; ̈ RONDOMYCIN
Antibacterial
OH O HO O
CONH2
OH
NMe2HH
OH
CH2 OH
Methadone me·tha·dön6-Dimethylamino-4,4-diphenylheptan-3-one; amidine; C21H27NO;76-99-3�Methadone Hydrochloride 1095-90-5; PHYSEPTONE
Opioid analgesic
and enantiomer
NMe"
H Me
H3C
O
Methadyl Acetate see Acetylmethadol
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3-56�Methallenestril (methallenoestril)
3-(6-Methoxy-2-naphthyl)-2,2-dimethylpentanoic acid; C18H22NO3;517-18-0Oestrogen
MeO
COOH
CH3
H
Me Me
and enantiomer
Methallibure see Metallibure
Methamphazone see Metamphazone
�Methandienone (BAN)17b-Hydroxy-17a-methylandrosta-1,4-diene-3-one; C20H28O2; 72-63-9
O
Me
H
H
H
Me Me
OH
Methanthelinium Bromide me·than·the·li·në·umDiethyl(methyl)[2-(xanthen-9-ylcarbonyloxy)ethyl]ammonium bromide;C21H26BrNO3; 53-46-3Anticholinergic
O
O
H
ONEt2Me
+
Br_
Methaphenilene me·tha·fe·ni·lënN-(2-Dimethylaminoethyl)-N-thenylaniline; C15H20N2S; 493-78-7Histamine H1-receptor antagonist
S NNMe2
Methapyrilene me·tha·pi·ri·lën2-(N-2-Pyridyl-N-2-thenylamino)ethyldimethylamine; C14H19N3S;91-80-5Histamine H1-receptor antagonist
S NNMe2
N
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3-57�Methaqualone me·tha·kwa·lön
2-Methyl-3-o-tolylquinazolin-4-(3H)-one; C16H14N2O; 72-44-6Hypnotic
N
N
OMe
Me
Metharbital (metharbitone) me·thar·bi·tal5,5-Diethyl-1-methylbarbituric acid; C9H14N2O3;50-11-3Anticonvulsant
NH
N OO
O
EtEt
Me
Methazolamide me·tha·zol·a·mïdN-(4-Methyl-2-sulfamoyl-D2-1,3,4-thiadiazolin-5-ylidene)acetamide; C5H8N4O3S2;554-57-4Carbonic anhydrase inhibitor
Me
H2N
O OS NAc
N N
S
Methdilazine meth·dil·a·zën10-(1-Methylpyrrolidin-3-ylmethyl)phenothiazine; C18H20N2S; 1982-37-2Histamine H1-receptor antagonist
N
S
N
Me
Methenamine Hippurate (hexamine hippurate) me·then·a·mën hi·pûr·rätA 1:1 complex of hexamine and hippuric acid; ; C6H12N4.C9H9NO3; 5714-73-8;HIPREX
Anti-infective
NN
N
N NHOOC
O
H.
Methenolone see Metenolone
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3-58Methestrol (promethoestrol) me·thës·trol
4,4¢-(1,2-Diethylethylene)di(o-cresol); C20H26O2; 130-73-4Oestrogen
HO
Me
OH
Me
Et
Et
* *
mixture of stereoisomers
Methetoin see Metetoin
Methicillin me·thi·si·lin(6R)-6-(2,6-Dimethoxybenzamido)penicillanic acid; meticillin (pINN);C17H20N2O6S;61-32-5Methicillin Sodium 7246-14-2; CELBENIN
Antibacterial
HN
NOO
S
H COOH
Me
Me
H H
OMe
OMe
Methimazole see Thiamazole
Methindizate see Metindizate
Methiodal Sodium me·thï·ö·dalSodium iodomethanesulfonate; CH2INaO3S; 126-31-8Contrast medium
I CH2SO3Na
Methisazone see Metisazone
Methixene see Metixene
Methocarbamol me·thö·kar·ba·mol2-Hydroxy-3-(2-methoxyphenoxy)propyl carbamate; C11H15NO5;532-03-6; ROBAXIN; ROBAXISAL FORTE*Skeletal muscle relaxant
O O NH2
H OH
OOMe
and enantiomer
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3-59Methohexital (methohexitone) me·thö·heks·i·tal
5-Allyl-1-methyl-5-(1-methylpent-2-ynyl)barbituric acid; C14H18N2O3; 18652-93-2�Methohexital Sodium 22151-68-4; BRIETAL
Anaesthetic
**
N
N
H2C
H3C
O
OMe
O
Me
H
mixture of 4 stereoisomers
Methoin see Mephenytoin
Methoserpidine me·thö·ser·pi·dënMethyl 11-demethoxy-10-methoxy-O-(3,4,5-trimethoxybenzoyl)reserpate;C33H40N2O9; 865-04-3Centrally-acting antihypertensive
NN
O
O
MeO
H
H
H
MeOOCOMe
OMe
OMe
OMe
H
�Methotrexate me·thö·treks·ät4-Amino-4-deoxy-10-methylpteroyl-L-glutamic acid; amethopterin; C20H22N8O5; 59-05-2Methotrexate Sodium MAXTREX
Cytotoxic
N
N
N
N
N
NHHOOC
H2N
NH2
Me
O
H COOH
Methotrimeprazine see Levomepromazine
�Methoxamine2-Amino-1-(2,5-dimethoxyphenyl)propan-1-ol; C11H17NO3; 390-28-3�Methoxamine Hydrochloride 61-16-5; VASOXINE
CH3
H OH
H NH2OMe
MeO
mixture of stereoisomers
* *
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3-60Methoxsalen (BAN) me·thoks·a·len
9-Methoxyfuro[3,2-g]chromen-7-one; C12H8O4; 298-81-7Aid to dermal pigmentation
O OO
OMe
Methoxyflurane me·thoks·ë·flûr·rän2,2-Dichloro-1,1-difluoroethyl methyl ether; C3H4Cl2F2O; 76-38-0 ¨METOFANE
Anaesthetic
ClOMe
Cl
F F
Methoxyphenamine me·thoks·ë·fen·a·mën2-Methoxy-a-methylphenethyl(methyl)amine; C11H17NO; 93-30-1Sympathomimetic
CH3
H NHMeOMe
and enantiomer
Methsuximide see Mesuximide
�Methyclothiazide me·thë·klö·thï·a·zïd(RS)-6-Chloro-3-chloromethyl-3,4-dihydro-2-methyl-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; C9H11Cl2N3O4S2; 135-07-9Diuretic
H2N
O OS
NMe
ClCl N
H
SOO
H
and enantiomer
Methyl Benzoquate më·thïl ben·zö·kwätMethyl 7-benzyloxy-6-butyl-1,4-dihydro-4-oxoquinoline-3-carboxylate; nequinate(pINN); C22H23NO4; 13997-19-8; ̈ LERBEK*Antiprotozoan
N
O
COOMe
O
H3C
H
Methyl Cysteine see Mecysteine
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3-61Methylbenzethonium Chloride më·thïl·ben·ze·thö·në·um
Benzyldimethyl-2-{2-[4-(1,1,3,3-tetramethylbutyl)-o-tolyloxy]ethoxy}-ethylammonium chloride; C28H44ClNO2; 25155-18-4Anti-infective
Me
MeMe Me Me
OO
NMeMe
Me
+Cl
_
�Methylchromone3-Methylchromen-4-one; C10H8O2; 85-90-50
O
O
Me
Methyldesorphine më·thïl·dez·or·fën(1) (-)-(5S)-4,5-Epoxy-6,9a-dimethylmorphin-6-en-3-ol; (2) 7,8-dihydro-6-deoxy-6,7-didehydromorphine; C18H21NO2; 16008-36-9Opioid analgesic
NMe
O
HO
H
Me
�Methyldopa më·thïl·dö·pa3-(3,4-Dihydroxyphenyl)-2-methyl-L-alanine; C10H13NO4; 555-30-6 (anhydrous);41372-08-1 (sesquihydrate); ALDOMET; DOPAMET; MEDOMET
Centrally-acting antihypertensive
COOHHO
HONH2Me
Methyldopate (BAN) më·thïl·dö·pät(1) Ethyl 3-(3,4-dihydroxyphenyl)-2-methyl-L-alaninate; (2) ethyl(-)-2-amino-2-(3,4-dihydroxybenzyl)propionate; C12H17NO4; 2544-09-4�Methyldopate Hydrochloride 2508-79-4; ALDOMET INJECTION
Centrally-acting antihypertensive
COOEtHO
HONH2Me
Methylene Blue see Methylthioninium Chloride
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3-62�Methylephedrine (BAN) më·thïl·e·fe·drën
(1RS,2RS)-2-Dimethylamino-1-phenylpropan-1-ol; C11H17NO; 552-79-4Sympathomimetic
NMe2
H OH
H Me
and enantiomer
Methylergometrine më·thïl·er·gö·me·trën(8R)-N-(1S)-1-(Hydroxymethyl)propyllysergamide; methylergonovine;C20H25N3O2; 113-42-8Methylergometrine Maleate 7054-07-1Oxytoxic
MeH
N
HN NH
CH3H
OOH
H
Methylpentynol më·thïl·pen·tin·ol3-Methylpent-1-yn-3-ol; C6H10O; 477-75-8Hypnotic; anxiolytic
H3COHH
CH
and enantiomer
Methylphenidate më·thïl·fe·ni·dätMethyl 2-phenyl-2-piperidylacetate; C14H19NO2; 113-45-1Methylphenidate Hydrochloride 298-59-9; RITALIN
Central nervous system stimulant
NH
COOMe*
*
mixture of 4 stereoisomers
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3-63�Methylphenobarbital (methylphenobarbitone) më·thïl·fë·nö·bar·bi·tal
(RS)-5-Ethyl-1-methyl-5-phenylbarbituric acid; mephobarbital (USAN);C13H14N2O3; 115-38-8; PROMINAL
Anticonvulsant
NH
N OO
O
Me
Et
and enantiomer
�Methylprednisolone më·thïl·pred·ni·so·lön(1) 11b,17a,21-Trihydroxy-6a-methylpregna-1,4-diene-3,20-dione; (2) 6a-methylprednisolone; C22H30O5; 83-43-2; MEDRONE
�Methylprednisolone Acetate 53-36-1; DEPO-MEDRONE
�Methylprednisolone Hydrogen Succinate 2921-57-5Methylprednisolone Sodium Succinate 2375-03-3; SOLU-MEDRONE
Methylprednisolone Suleptonate 90350-40-6; U-67,590ACorticosteroid
O
Me
Me
H
H
H
OH
OHMe
HO
O
�Methyltestosterone më·thïl·tes·tos·ter·rön17b-Hydroxy-17a-methylandrost-4-en-3-one; C20H30O2; 58-18-4; ¨ORANDRONE;¨ SESORAL*Anabolic steroid; androgen
O
Me
H
H
H
OHMe Me
�Methylthioninium Chloride / Methylene Blue më·thïl·thï·ö·nin·ë·um klor·rïd3,7-Bis(dimethylamino)phenothiazin-5-ium chloride trihydrate; CI basic blue 9trihydrate; C16H18ClN3S,3H2O; 7220-79-3Antidote
S
N
Me2N NMe2+
Cl_
H2O3
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3-64Methyprylon (methyprylone) me·thë·prï·lon
(RS)-3,3-Diethyl-5-methylpiperidine-2,4-dione; C10H17NO2; 125-64-4; NOLUDAR
Hypnotic
HN O
O
Et
EtMe
H
and enantiomer
Methyridine (BAN) me·thir·ri·dën2-(2-Methoxyethyl)pyridine; C8H11NO; 114-91-0Anthelmintic
N OMe
Methysergide me·thë·ser·jïd(8R)-N-(1S)-(1-Hydroxymethyl)propyl-1-methyllysergamide; C21H27N3O2;361-37-5�Methysergide Maleate 129-49-7; DESERIL
Serotonin receptor antagonist
MeH
N
MeN NH
CH3H
OOH
H
Metiamide me·tï·a·mïd1-Methyl-3-[2-(5-methylimidazol-4-ylmethylthio)ethyl]thiourea; C9H16N4S2; 34839-70-8Histamine H2-receptor antagonist
H
H3CN N
S
NNH
Me
S
H
Metindizate (methindizate) me·tin·di·zät2-(1-Methylperhydroindol-3-yl)ethyl benzilate; C25H31NO3; 15687-33-9Metindizate Hydrochloride ¨ ISAVERIN*Antispasmodic
N
O
HOO
Me
**
*
mixture of 8 stereoisomers
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3-65Metioprim me·tï·ö·prim
5-(3,5-Dimethoxy-4-methylthiobenzyl)pyrimidine-2,4-diyldiamine; C14H18N4O2S;68902-57-8Antibacterial
N
N
OMe
MeS
MeO
NH2
NH2
�Metipranolol me·ti·pra·no·lol4-(2-Hydroxy-3-isopropylaminopropoxy)-2,3,6-trimethylphenyl acetate;C17H27NO4; 22664-55-7; MINIMS METIPRANOLOL
Beta-adrenoceptor antagonist
O NHPr i
Me
Me
MeCOO
Me
OHH
and enantiomer
Metirosine me·tîr·rö·sën(-)-a-Methyl-L-tyrosine; C10H13NO3; 672-87-7; MK-781; L-588357-0Catecholamine synthesis inhibitor
COOH
NH2MeHO
�Metisazone (methisazone)1-Methylindoline-2,3-dione 3-thiosemicarbazone; C10H10N4OS;1910-68-5
N O
Me
NN NH2
S
H
Metixene (methixene) me·tiks·ën(RS)-9-(1-Methyl-3-piperidylmethyl)thioxanthene; C20H23NS; 4969-02-2�Metixene Hydrochloride 7081-40-5Anticholinergic
S
NMeH
and enantiomer
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3-66Metizoline (metyzoline) me·tï·zo·lën
2-(2-Methylbenzo[b]thienylmethyl)-2-imidazoline; C13H14N2S;17692-22-7Vasoconstrictor
S MeN
NH
�Metoclopramide me·tö·klö·pra·mïd4-Amino-5-chloro-N-(2-diethylaminoethyl)-2-methoxybenzamide; C14H22ClN3O2;364-62-5�Metoclopramide Hydrochloride 7232-21-5 (anhydrous); 34143-57-6 (hydrate);¨EMEQUELLE; GASTROBID; GASTROMAX; MAXOLON; MIGRAVESS*; PARAMAX*; PRIMPERAN
Antiemetic
NNEt2Cl
H2N OMe
O
H
�Metofoline(RS)-1-(4-Chlorophenethyl)-1,2,3,4-tetrahydro-6,7-dimethoxy-2-methyl-isoquinoline; C20H24ClNO2; 2154-02-1
NMe
Cl
OMe
MeO
H
and enantiomer
Metolazone me·to·la·zön(RS)-7-Chloro-1,2-dihydro-2-methyl-4-oxo-3-o-tolylquinazoline-6-sulfonamide;C16H16ClN3O3S; 17560-51-9; METENIX
Diuretic
HN
N
OMe
MeCl
H2NO2S
H
and enantiomer
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3-67Metomidate me·tö·mi·dät
Methyl 1-(1-phenylethyl)imidazole-5-carboxylate; C13H14N2O2;5377-20-8Metomidate Hydrochloride 35944-74-2; ̈ HYPNODIL
Anaesthetic; sedative
NN
HMe
COOMe
and enantiomer
Metopimazine me·tö·pi·ma·zën1-[3-(2-Methylsulfonylphenothiazin-10-yl)propyl]piperidine-4-carboxamide;C22H27N3O3S2; 14008-44-7Antiemetic
N
S
N
CONH2
SO2Me
Metopon me·tö·pon(1) (-)-(5R)-4,5-Epoxy-3-hydroxy-5,9a-dimethylmorphinan-6-one; (2) 6-deoxy-7,8-dihydro-5-methyl-6-oxomorphine; C18H21NO3; 143-52-2Opioid analgesic
NMe
O
HO
H
O
Me
Metoprolol me·to·pro·lol1-Isopropylamino-3-p-(2-methoxyethyl)phenoxypropan-2-ol; C15H25NO3; 54163-88-1�Metoprolol Tartrate 56392-17-7; BETALOC; CO-BETALOC*; LOPRESOR
Beta-adrenoceptor antagonist
O NHPr iOHH
MeO
and enantiomer
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3-68Metoserpate me·tö·ser·pät
Methyl O-methyl-18-epireserpate; C24H32N2O5; 1178-28-5Metoserpate Hydrochloride 1178-29-6Tranquilliser
NN
MeOH
H
H
OMe
OMe
MeOOC
H
Metrenperone me·tren·pe·rön3-[2-(4-p-Fluorobenzoylpiperidino)ethyl]-2,7-dimethylpyrido[1,2-a]pyrimidin-4-one; C24H26FN3O2; 81043-56-3; R509705HT2-Serotonin receptor antagonist (veterinary)
N
N
N
O
F
O
Me
Me
�Metrifonate (metriphonate) me·tri·fo·nät(RS)-Dimethyl 2,2,2-trichloro-1-hydroxyethylphosphonate; trichlorfon (USAN);C4H8Cl3O4P; 52-68-6Insecticide; anthelmintic
P
O
OMe
Cl3C
OHH
OMe
and enantiomer
Metrizamide me·tri·za·mïd2-[3-Acetamido-2,4,6-tri-iodo-5-(N-methylacetamido)benzamido]-2-deoxy-D-glucose; C18H22I3N3O8; 55134-11-7; AMIPAQUE
Contrast medium
II
I
NHAcMeN
NHO
Ac
O
CH2OH
OH
OH
HO
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3-69�Metronidazole me·trö·nï·da·zôl
2-(2-Methyl-5-nitroimidazol-1-yl)ethanol; C6H9N3O3; 443-48-1; ANABACT; ELYZOL;FLAGYL; FLAGYL COMPAK*; ̈ METRONEX; METROTOP; METROGEL; NORITATE; ROZEX; ̈ TORGYL;ZADSTAT; zidovalAntiprotozoan; antibacterial
N
N MeO2N
OH
�Metronidazole Benzoate (BAN)2-(2-Methyl-5-nitroimidazol-1-yl)ethyl benzoate; C13H13N3O4;13182-89-3; FLAGYL SAntiprotozoan; antibacterial
N
N MeO2N
O
O
�Metyrapone me·tï·ra·pön2-Methyl-1,2-di-(3-pyridyl)propan-1-one; C14H14N2O; 54-36-4; METOPIRONE
Adrenocortical enzyme inhibitor
N
Me Me
O
N
Metyzoline see Metizoline
�Mexenone meks·e·nön2-Hydroxy-4-methoxy-4¢-methylbenzophenone; C15H14O3; 1641-17-4; UVISTAT
Sunscreen
O
MeMeO OH
Mexiletine meks·ïl·e·tën1-Methyl-2-(2,6-xylyloxy)ethylamine; C11H17NO; 31828-71-4�Mexiletine Hydrochloride 5370-01-4; MEXITIL
Antiarrhythmic
OCH3
Me
Me
H NH2
and enantiomer
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3-70�Mezlocillin mez·lö·si·lin
(6R)-6-[N-(3-Methylsulfonyl-2-oxoimidazolidin-l-ylcarbonyl)-D-phenylglycylamino]penicillanic acid; C21H25N5O8S2; 51481-65-3Antibacterial
N
N
OH
NHHH
Me
Me
COOHH
S
ON
NH
O
O
SO O
CH3
Mianserin mï·an·se·rin(RS)-1,2,3,4,10,14b-Hexahydro-2-methyldibenzo[c,f]pyrazino[1,2-a]azepine;C18H20N2; 24219-97-4�Mianserin Hydrochloride 21535-47-7Antidepressant
N
NMe
H
and enantiomer
Mibefradil mi·be·fra·dil(1S,2S)-2-{2-[(3-Benzimidazol-2-ylpropyl)(methyl)amino]ethyl}-6-fluoro-1,2,3,4-tetrahydro-1-isopropyl-2-naphthyl methoxyacetate; C29H38FN3O3; 116644-53-2;POSICOR
Mibefradil Hydrochloride (1:2) 116666-63-8; Ro 40-5967/001Calcium antagonist; vasodilator
O
N
HN
N
OMe
O
Pri H
F Me
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3-71Mibolerone mï·bol·e·rön
17b-Hydroxy-7a,17-dimethylestr-4-en-3-one; C20H30O2; 3704-09-4;U-10997Anabolic steroid; androgen
O Me
Me Me
OH
H H
HH
�Miconazole mï·kon·a·zôl(RS)-1-[2,4-Dichloro-b-(2,4-dichlorobenzyloxy)phenethyl]imidazole;C18H14Cl4N2O; 22916-47-8�Miconazole Nitrate 22832-87-7; ACNIDAZIL*; ̈ CONODERM; DAKTACORT*; DAKTARIN;GYNO-DAKTARIN*; ̈ SUROLAN*Antifungal
and enantiomer
NN
Cl Cl
O
Cl Cl
H
�Midazolam mï·däz·ö·lam8-Chloro-6-(2-fluorophenyl)-1-methyl-4H-imidazo[1,5-a][1,4]benzodiazepine;C18H13ClFN3; 59467-70-8; Ro 21-3971Midazolam Hydrochloride 59467-96-8; HYPNOVEL
Premedicament sedative
N
N
NMe
F
Cl
Midodrine mï·dö·drën(RS)-N1-(b-Hydroxy-2,5-dimethoxyphenethyl)glycinamide; C12H18N2O4; 42794-76-3Midodrine Hydrochloride 3092-17-9; ST 1085Alpha-adrenoceptor agonist
NNH2
OMe
MeOOHH
O
H
and enantiomer
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3-72Mifepristone mi·fe·pris·tön
11b-(4-Dimethylaminophenyl)-17b-hydroxy-17a-prop-1-ynylestra-4,9-dien-3-one;C29H35NO2; 84371-65-3; MIFEGYNE
Progesterone antagonist
O
OHMe
Me2N
H
H
H
CH3
Miglitol mi·gli·tol(2R,3R,4R,5S)-1-(2-Hydroxyethyl)-2-(hydroxymethyl)piperidine-3,4,5-triol;C8H17NO5; 72432-03-2; BAY m 1099Glucosidase inhibitor
N
HOOH
OHHO
OH
Mikamycin mi·ka·mï·sinAntimicrobial substances produced by Streptomyces mitakaensis; certain componentsare identical with some constituents of ostreogrycin, pristinamycin andvirginiamycin; 11006-76-10Antibiotic
Milenperone mi·len·pe·rön5-Chloro-1-[3-(4-p-fluorobenzoylpiperidino)propyl]-1,3-dihydrobenzimidazol-2-one; C22H23ClFN3O2; 59831-64-0; R 34009Antipsychotic
N
O
F
Cl ON
N
Milnacipran mil·na·si·pran(±)-cis-2-Aminomethyl-N,N-diethyl-1-phenylcyclopropanecarboxamide;C15H22N2O; 92623-85-3Milnacipran Hydrochloride 101152-94-7Antidepressant
NEt2
O
NH2
and enantiomer
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3-73Milrinone mil·ri·nön
1,6-Dihydro-2-methyl-6-oxo-[3,4¢-bipyridine]-5-carbonitrile; C12H9N3O; 78415-72-2; PRIMACOR
Inotropic
HN
N
CN
O
Me
Miltefosine mil·tef·o·sën[2-(Trimethylammonio)ethyl][hexadecyloxyphosphonate]; C21H46NO4P; 58066-85-6; D-18506; HDPCAntineoplastic
NMe3
O
O
OP
O
CH3
+
_
Minaprine mi·na·prën4-Methyl-6-phenylpyridazin-3-yl(2-morpholinoethyl)amine; C17H22N4O; 25905-77-5Minaprine Hydrochloride 25953-17-7 (2HCl); Agr-1240; CB-30038Antidepressant
NN
NN
OMe
H
Minaxolone mi·naks·o·lön11a-Dimethylamino-2b-ethoxy-3a-hydroxy-5a-pregnan-20-one; C25H43NO3; 62571-87-3Minaxolone Citrate CCI 12923Anaesthetic
HO
EtOMe
MeMe2N
CH3O
H H
H
Minepentate mï·ne·pen·tät2-(2-Dimethylaminoethoxy)ethyl 1-phenylcyclopentanecarboxylate; C18H27NO3;13877-99-1Antiparkinsonian
OO
NMe2
O
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3-74Minocromil mï·no·krö·mil
6-Methylamino-4-oxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid;C18H16N2O6; 85118-44-1Minocromil Sodium 75452-62-9Prophylaxis of allergic conditions
N O
O
COOH
NHMe
HOOC
Prn
Minocycline mï·nö·sï·klën(1) (1) (4S,4aS,5aR,12aS)-4,7-bis(dimethylamino)-1,4,4a,5,5a,6,11,12a-octahydro-3,10,12,12a-tetrahydroxy-1,11-dioxonaphthacene-2-carboxamide;(2) 6-demethyl-6-deoxy-7-dimethylaminotetracycline; C23H27N3O7; 11008-90-8�Minocycline Hydrochloride 13614-98-7; AKNEMIN; DENTOMYCIN; MINOCIN
Antibiotic
OH O HO O
CONH2
OH
NMe2HH
OH
NMe2
�Minoxidil min·oks·i·dil2,6-Diamino-4-piperidinopyrimidine 1-oxide; C9H15N5O; 38304-91-5; LONITEN;REGAINE
Vasodilator
N
NN NH2
NH2
O
Mioflazine mï·ö·flä·zën1-[4,4-Bis(4-fluorophenyl)butyl]-4-(2,6-dichlorophenylcarbamoylmethyl)-piperazine-2-carboxamide; C29H30Cl2F2N4O2; 79467-23-5Mioflazine Hydrochloride 79467-24-6; R 51469Calcium antagonist
N
F
F
NN
CONH2
O
Cl
Cl
H
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3-75Miristalkonium Chloride mi·ri·stal·kö·në·um
Benzyldimethyl(tetradecyl)ammonium chloride; C23H42ClN; 139-08-2Anti-infective
N[CH2] 13CH3
MeMe
+
Cl_
Mirtazapine mer·tä·za·pën(RS)-1,2,3,4,10,14b-Hexahydro-2-methylpyrazino[2,1-a]pyrido[2,3-c][2]benz-azepine; C17H19N3; 61337-67-5; ZISPIN
Antidepressant
N
N
N
Me
H
and enantiomer
Misonidazole mï·sö·nïd·a·zôl(RS)-3-Methoxy-1-(2-nitroimidazol-1-yl)propan-2-ol; C7H11N3O4; 13551-87-6Antiprotozoan
N
N OMeOHH
NO2
and enantiomer
Misoprostol mï·sö·pros·tol(1) (±)-Methyl 7-[1R,2R,3R)-3-hydroxy-2-[(E)-(4RS)-4-hydroxy-4-methyloct-1-enyl]-5-oxocyclopentyl]heptanoate; (2) (±)-methyl (13E)-11,16-dihydroxy-16-methyl-9-oxoprost-13-enoate; C22H38O5; 59122-46-2; ARTHROTEC*; CYTOTEC;NAPRATEC*Prostanoid gastric antisecretory
H
HHO
OCOOMe
CH3
Me OH
H
H
and enantiomer at C*
*
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3-76�Mitobronitol mï·tö·bro·ni·tol
1,6-Dibromo-1,6-dideoxy-D-mannitol; C6H12Br2O4; 488-41-5; ©MYELOBROMOL
Cytotoxic
HHO
HHO
H OH
H OH
Br
Br
�MitoclomineBis(2-chloroethyl)(4-methoxy-3-methyl-1-naphthyl)amine; C16H19Cl2NO; 17692-54-5
OMe
Me
NClCl
Mitomycin mï·tö·mï·sin(1S,2S,9S,9aR)-7-Amino-2,3,5,8,9,9a-hexahydro-9a-methoxy-6-methyl-5,8-dioxo-1,2-epimino-1H-pyrrolo[1,2-a]indol-9-ylmethyl carbamate; mitomycin C;C15H18N4O5; 50-07-7; MITOMYCIN C KYOWA
Cytotoxic
N
O
O
H2N
Me
OCONH2
HOMe
NH
Mitopodozide mï·tö·pö·dö·zïd2¢-Ethylpodophyllohydrazide; C24H30N2O8; 1505-45-8Cytotoxic
O
O
OH OH
HN
NHEt
OMe
OMe
MeO
O
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3-77Mitoquidone mï·to·kwi·dön
5,14-Dihydrobenz[5,6]isoindolo[2,1-b]isoquinoline-8,13-dione; C20H13NO2;91753-07-0; GR 30921Cytotoxic
N
O
O
�Mitotenamine5-Bromo-3-benzo[b]thienylmethyl(2-chloroethyl)ethylamine; C13H15BrClNS; 7696-00-6
S
NCl
CH3
Br
Mitoxantrone / Mitozantrone mï·tö·zan·trön1,4-Dihydroxy-5,8-bis[2-(2-hydroxyethylamino)ethylamino]anthraquinone;C22H28N4O6; 65271-80-9Mitoxantrone Hydrochloride / Mitozantrone Hydrochloride 70476-82-3;NOVANTRONE
Cytotoxic
NH
NH
NHO
NHO
O
O
OH
OH
H
H
Mitozolomide mï·tö·zo·lö·mïd3-(2-Chloroethyl)-3,4-dihydro-4-oxoimidazo[5,1-d]-1,2,3,5-tetrazine-8-carboxamide; C7H7ClN6O2; 85622-95-3; M&B 39565; CCRG 81010; 46241 RPCytotoxic
N N
NN
N
Cl
O
CONH2
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3-78Mivacurium Chloride mi·va·kûr·rë·um
A mixture of the (1R,1¢R,2S,2¢S), (1R,1¢R,2S,2¢R) and (1R,1¢R,2R,2¢R)stereoisomers (the trans-trans, trans-cis and cis-cis isomers respectively) of(E)-1,1¢,2,2¢,3,3¢,4,4¢-octahydro-6,6¢,7,7¢-tetramethoxy-2,2¢-dimethyl-1,1¢-bis(3,4,5-trimethoxybenzyl)-2,2¢-[oct-4-enedioylbis(oxytrimethylene)]di-isoquinolinium dichloride; C58H80Cl2N2O14; 106861-44-3 (total racemate); MIVACRON
Skeletal muscle relaxant
N OMeO
MeO
OMe
OMeMeO
OH Me
+
2
2Cl_
Mizolastine mï·zö·las·tën2-{1-[1-(4-Fluorobenzyl)-1H-benzimidazol-2-yl]-4-piperidyl(methyl)amino}pyrimidin-4(1H)-one; C24H25FN6O; 108612-45-9; MIZOLLEN
Histamine H1-receptor antagonist
N
N N
F
N N
HN
O
Me
Moclobemide mö·klö·be·mïd4-Chloro-N-(2-morpholinoethyl)benzamide; C13H17ClN2O2; 71320-77-9; MANERIX
Antidepressant
O
NN
Cl
O
H
Modafinil mö·da·fi·nil2-(Benzhydrylsulfinyl)acetamide; C15H15NO2S; 68693-11-8Treatment of narcolepsy and hypersomnia
S CONH2
O
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3-79Modipafant mö·di·pa·fant
Ethyl (R)-4-(2-chlorophenyl)-1,4-dihydro-6-methyl-2-[4-(2-methyl-1H-imidazo[4,5-c]pyridin-1-yl)phenyl]-5-(2-pyridylcarbamoyl)pyridine-3-carboxylate;C34H29ClN6O3; 122957-06-6; 122956-68-7 (racemate);UK-80067Platelet activating factor antagonist
H
H
N
N
NMe
O Cl
COOEt
N
NN
Me
H
Moexipril mö·eks·i·pril(3S)-2[(2S)-2{[(1S)-(1-Ethoxycarbonyl)-3-phenylpropyl]amino}propanoyl]-1,2,3,4-tetrahydro-6,7-dimethoxyquinoline-3-carboxylic acid; C27H34N2O7; 82586-52-5Moexipril Hydrochloride 82586-52-5; PERDIX
Angiotensin converting enzyme inhibitor; hypertension
NNMeO
O
MeOH
COOH
H Me COOEt
H
Molgramostim mol·gra·mos·timRecombinant granulocyte macrophage colony stimulating factor expressed by E.coli; C639H1007N171O196S8; 99283-10-0; LEUCOMAX
ImmunostimulantMolgramostim has the following amino acid sequence:
APARSPSPST QPWEHVNAIQ EARRLLNLSR
DTAAEMNETV EVISEMFDLQ EPTCLQTRLE
LYKQGLRGSL TKLKGPLTMM ASHYKQHCPP
TPETSCATQI ITFESFKENL KDFLLVIPFD
CWEPVQE
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3-80Molindone mol·in·dön
(RS)-3-Ethyl-1,5,6,7-tetrahydro-2-methyl-5-(morpholinomethyl)indol-4-one;C16H24N2O2; 7416-34-4Molindone Hydrochloride 15622-65-8Antipsychotic
O
N
N
O
Me
Et
H
Hand enantiomer
Molsidomine mol·si·dö·mënN-Ethoxycarbonyl-3-morpholinosydnonimine; C9H14N4O4; 25717-80-0;CAS 276Vasodilator
N
N_
O
NN
COOEt
+
Mometasone mö·me·ta·sön9a,21-Dichloro-11b,17-dihydroxy-16a-methylpregna-1,4-diene-3,20-dione;C22H28Cl2O4; 105102-22-5Mometasone Furoate 83919-23-7; ELOCON; NASONEX
Corticosteroid
O
Me Me
HOMe
O
O O
O
Cl
HCl
H
Monensin mo·nen·sinAn antibacterial substance produced by Streptomyces cinnamonensis;4-{2-[2-ethyl-3¢-methyl-5¢-(tetrahydro-6-hydroxy-6-hydroxymethyl-3,5-dimethylpyran-2-yl)perhydro-2,2¢-bifuran-5-yl]-9-hydroxy-2,8-dimethyl-1,6-dioxaspiro[4.5]dec-7-yl}3-methoxy-2-methylpentanoic acid; C36H62O11; 17090-79-8Monensin Sodium 22373-78-0; ̈ ELANCOBAN; ̈ ROMENSIN
Antiprotozoan
OOO
O
O
Me
COOH
OMe
MeMe
HOHO
Me
Et
Me
OH
Me Me
HH H
H
H
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3-81Monoctanoin (BAN) mo·nok·ta·nö·in
A mixture of 1-O-decanoyl-sn-glycerol-3,1,2-O-dioctanoyl-sn-glycerol-3 and 1-O-octanoyl-sn-glycerol-3 in which the molecular ratio-range of the mono-octyl ester tothe sum of the monodecanoyl and dioctanoyl esters is 80 to 85:15 to 10Dissolution of cholesterol gallstones
Monosulfiram see Sulfiram
Montelukast mon·të·lü·kast(R)-[1-(1-{3-[2-(7-Chloro-2-quinolyl)vinyl]phenyl}-3-[2-(1-hydroxy-1-methylethyl)phenyl]propylthiomethyl)cyclopropyl]acetic acid; C35H36ClNO3S;158966-92-8; MK-0476Montelukast Sodium 151767-02-1; SINGULAIR
Leukotriene D4-receptor antagonist; antiasthmatic
NCl
S
COOH
HO
Me
Me
H
Mopidamol mö·pi·da·mol2,2¢,2¢¢,2¢¢¢-(4-Piperidinopyrimido[5,4-d]pyrimidine-2,6-diyldinitrilo)tetraethanol;C19H31N7O4; 13665-88-8; Ra 233Cytotoxic
N
NN
N
N
N
NOH
OH
HO
HO
Moracizine mor·ra·si·zënEthyl 10-(3-morpholinopropionyl)phenothiazin-2-ylcarbamate; C22H25N3O4S;31883-05-3; moricizine (USAN)Moracizine Hydrochloride 29560-58-8; ETHMOZINE
Antiarrhythmic
N
S
N
O
O
NCOOEt
H
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3-82Morantel mo·ran·tel
(E)-1,4,5,6-Tetrahydro-1-methyl-2-[2-(3-methyl-2-thienyl)vinyl]pyrimidine;C12H16N2S; 20574-50-9Morantel Tartrate 26155-31-7; ̈ PARATECT
Morantel Citrate ¨EXHELM
Anthelmintic
N
N
S
H
H
MeMe
Morazone mo·ra·zön2,3-Dimethyl-4-(3-methyl-2-phenylmorpholinomethyl)-1-phenyl-3-pyrazolin-5-one; C23H27N3O2; 6536-18-1Morazone Hydrochloride 50321-35-2Analgesic
N
N N
O
MeO
Me Me
**
mixture of 4 stereoisomers
Moroctocog Alfa mo·rok·to·cog al·fa(1—742)–(1637—1648)-Blood-coagulation factor VIII (human reduced) complexwith 1649—2332–blood-coagulation factor VIII (human reduced);C3953H6020N1040O1158S29 + C3553H5412N956O1028S33
Blood-coagulation factor
Moroxydine mo·roks·ë·dën1-(Morpholinoformimidoyl)guanidine; C6H13N5O; 3731-59-7Antiviral
O
N N NH2
NH NH
H
Morpheridine mor·fe·ri·dënEthyl 1-(2-morpholinoethyl)-4-phenylpiperidine-4-carboxylate;morpholinoethylnorpethidine; C20H30N2O3; 469-81-8Opioid analgesic
O
NN
COOEt
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3-83Morphine (BAN) mor·fën
(5R,6S)-7,8-Didehydro-4,5-epoxy-9a-methylmorphinan-3,6-diol; C17H19NO3;57-27-2�Morphine Hydrochloride 52-26-6�Morphine Sulphate 64-31-3; MORCAP; MST CONTINUS; ORAMORPH; RAPIJECT; SEVREDOL
Morphine Tartrate 302-31-8; CYCLIMORPH*Opioid analgesic
NMe
O
HO
H
HO
Moxaverine moks·a·ver·rën1-Benzyl-3-ethyl-6,7-dimethoxyisoquinoline; C20H21NO2; 10539-19-2Moxaverine Hydrochloride 1163-37-7Antispasmodic
NMeO
MeO Et
Moxidectin moks·i·dek·tin(6R,15S)-5-O-Demethyl-28-deoxy-25-[(E)-1,3-dimethylbut-1-enyl]-6,28-epoxy-23-oxomilbemycin B (E)-23-O-methyloxime; C37H53NO8;113507-06-5Parasiticide (veterinary)
O
OMe
Me
O
O
MeH
Me
HH
NOMe
HO
H
MeOHH
OH
H
HMe
Me
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3-84Moxifloxacin moks·i·floks·a·sin
1-Cyclopropyl-6-fluoro-8-methoxy-7-[(4aS,7aS)-octahydro-6H-pyrrolo[3,4-b]pyridin-6-yl]-4-oxo-1,4-dihydroquinoline-3-carboxylic acid; C21H24FN3O4; 151096-09-2
Antibacterial
N
O
OMe
COOHF
NHN
H
H
Moxipraquine moks·i·pra·kwën4-{4-[6-(6-Methoxy-8-quinolylamino)hexyl]piperazin-1-yl}butan-2-ol; C24H38N4O2;23790-08-1Protozoacide
and enantiomer
N
N CH3
H OH
MeO
N
N
Moxonidine moks·o·ni·dën4-Chloro-6-methoxy-2-methylpyrimidine-5-yl(2-imidazolin-2-yl)amine;C9H12ClN5O; 75438-57-2; PHYSIOTENS
Imidazoline I1-receptor agonist; antihypertensive
NH
N N
N
N
Me
Cl
MeO
H
Moxisylyte / Thymoxamine moks·is·i·lït/thï·moks·a·mën4-(2-Dimethylaminoethoxy)-5-isopropyl-2-methylphenyl acetate; C16H25NO3; 54-32-0�Moxisylyte Hydrochloride / Thymoxamine Hydrochloride 964-52-3; MINIMS
THYMOXAMINE; OPILON
Alpha-adrenoceptor antagonist
Pr i
ONEt2Me
AcO
Mucin, Gastric see Gastric Mucin
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3-85Mupirocin mü·pï·rö·sin
9-[(2E)-4-[(2S,3R,4R,5S)-5-[(2S,3S,4S,5S)-2,3-Epoxy-5-hydroxy-4-methylhexyl]tetrahydro-3,4-dihydroxypyran-2-yl]-3-methylbut-2-enoyloxy]nonanoic acid; C26H44O9; 12650-69-0Mupirocin Calcium BACTROBAN
Antibiotic
O
O
H3C
OH
Me
O
OHHO
Me O
[CH2]8 COOH
Mustine see Chlormethine
Muzolimine mü·zo·li·mën(RS)-3-Amino-1-[1-(3,4-dichlorophenyl)ethyl]-2-pyrazolin-5-one; C11H11Cl2N3O;55294-15-0Diuretic
NN
O
NH2MeH
Cl
Cl
and enantiomer
Mycophenolic Acid mï·kö·fe·no·lik(E)-6-(1,3-Dihydro-4-hydroxy-6-methoxy-7-methyl-3-oxoisobenzofuran-5-yl)-4-methylhex-4-enoic acid; C17H20O6; 24280-93-1Mycophenolate Mofetil 115007-34-6; CELLCEPT
Immunomodulator
OCOOH
O
Me
OMe
OH Me
Myralact mï·ra·lakt(2-Hydroxyethyl)tetradecylammonium lactate; C19H41NO4; 15518-87-3Anti-infective
HONH
[ CH2] 13CH3 ,CH3CHCOOH
OH
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3-86Myrophine mï·ro·fën
(1) (-)-(5R,6S)-3-Benzyloxy-4,5-epoxy-9a-methylmorphin-7-en-6-yl myristate; (2)3-O-benzyl-6-O-myristoylmorphine; C38H51NO4; 467-18-5Opioid analgesic
NMe
O
O
H
O
[ CH2] 12CH3O
Nabilone na·bi·lön(±)-(6aR,10aR)-3-(1,1-Dimethylheptyl)-6a,7,8,9,10,10a-hexahydro-1-hydroxy-6,6-dimethyl-6H-benzo[c]chromen-9-one; C24H36O3;51022-71-0; CESAMET
Antiemetic
O
CH3
O
HOMe Me
H
HMe
Me
and enantiomer
�Nabumetone na·bü·me·tön4-(6-Methoxy-2-naphthyl)butan-2-one; C15H16O2; 42924-53-8; RELIFEX
Analgesic; anti-inflammatory
CH3
O
MeO
Nadide nä·dïd1-(3-Carbamoylpyridinio)-b-D-ribofuranoside 5-(adenosine-5¢-diphosphate);C21H27N7O14P2; 53-84-9Antagonist to alcohol and opioid analgesics
+ OP
O
O_
O
HOOH
O
N
CONH2
P O
OHOH
O
O
OH
N
NN
N
NH2
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3-87Nadifloxacin na·di·floks·a·sin
(RS)-9-Fluoro-6,7-dihydro-8-(4-hydroxypiperidino)-5-methyl-1-oxo-1H,5H-benzo[ij]quinolizine-2-carboxylic acid; C19H21FN2O4; 124858-35-1; OPC-7251Antibacterial
NN
OCOOH
Me
F
HO
H
and enantiomer
Nadolol na·do·lol(2R,3S)-5-(3-tert-Butylamino-2-hydroxypropoxy)-1,2,3,4-tetrahydronaphthalene-2,3-diol; C17H27NO4; 42200-33-9; CORGARD; CORGARETIC*Beta-adrenoceptor antagonist
O NHBu t
OH
HOH OH
*
and enantiomer at C*
�Nadroparin Calcium na·drö·pa·rinCalcium salt of depolymerised heparin obtained by nitrous acid degradation ofheparin from pork intestinal mucosa; the majority of the components have a 2-O-sulfo-a-L-idopyranosuronic acid structure at the non-reducing end and a 6-O-sulfo-2,5-anhydro-D-mannitol structure at the reducing end of their chain; the averagemolecular weight is about 4500; the degree of sulfation is about 2.1 perdisaccharide unit; CY 216Anticoagulant
Nafarelin na·fa·rë·linC66H83N17O13; 76932-56-4Nafarelin Acetate 86220-42-0; SYNAREL
Gonadorelin analogue
Nafarelin has the following amino acid sequence:
<Glu–His–Trp–Ser–Tyr–3–(naphthyl)-D-Ala–Leu–
Arg–Pro–Gly–NH2
Nafazatrom na·fä·za·trom3-Methyl-1-[2-(2-naphthyloxy)ethyl]-5-pyrazolone; C16H16N2O2;59040-30-1; BAY g 6575Antithrombotic
ON
N
O
Me
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3-88Nafcillin naf·si·lin
(6R)-6-(2-Ethoxy-1-naphthamido)penicillanic acid; C21H22N2O5S;147-52-4Nafcillin Sodium 7717-50-6 (hydrate); 985-16-0 (anhydrous); ̈ NAFPENZAL*Antibacterial
HN
NOO
S
H COOH
Me
Me
H H
OEt
�Nafenopin(RS)-2-Methyl-2-[4-(1,2,3,4-tetrahydro-1-naphthyl)phenoxy]propionic acid;C20H22O3; 3771-19-5
Me
COOHO
MeH
and enantiomer
Naftalofos (naphthalophos) naf·ta·lö·fosDiethyl naphthalimido-oxyphosphonate; C16H16NO6P; 1491-41-4Anthelmintic
P
O
OEt
ON
O
O
OEt
Naftazone naf·ta·zön1,2-Naphthoquinone 2-semicarbazone; C11H9N3O2; 15687-37-3Haemostatic
O
NN NH2
O
H
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3-89Naftidrofuryl naf·tï·drö·fûr·ïl
all rac-2-Diethylaminoethyl 3-(1-naphthyl)-2-tetrahydrofurfurylpropionate;C24H33NO3; 31329-57-4�Naftidrofuryl Oxalate nafronyl oxalate (USAN); 3200-06-4; PRAXILENE
Vasodilator
ONEt2
O
O
*
*
mixture of stereoisomers
Naftifine naf·ti·fën(E)-Cinnamyl(methyl)(1-naphthylmethyl)amine; C21H21N; 65472-88-0;SN 105-843Antifungal
N
Me H
H
Nagrestipen na·gre·sti·penA genetically-engineered variant of a naturally occurring stem cell inhibitingprotein; macrophage inflammatory protein-1a; C338H516N88O110S4;150387-18-1; MIP-1a; BB-10010Protection of bone marrow stem cellsNagrestipen has the following amino acid sequence:
SLAADTPTAC CFSYTSRQIP QNFIAAYFET
SSQCSKPGVI FLTKRSRQVC ADPSEEWVQK
YVSDLELSA
Nalbuphine nal·bü·fën(1) (-)-(5R,6S,14S)-9a-Cyclobutylmethyl-4,5-epoxymorphinan-3,6,14-triol; (2)17-cyclobutylmethyl-7,8-dihydro-14-hydroxy-17-normorphine; C21H27NO4; 20594-83-6Nalbuphine Hydrochloride 23277-43-2; NUBAIN
Analgesic; opioid antagonist
N
O
HO
OH
HO
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3-90�Nalidixic Acid na·li·diks·ik
1-Ethyl-1,4-dihydro-7-methyl-4-oxo-1,8-naphthyridine-3-carboxylic acid;C12H12N2O3; 389-08-2; MICTRAL*; NEGRAM; URIBEN
Antibacterial
N N
O
COOH
Et
Me
Nalmefene nal·me·fën(5S)-9a-Cyclopropylmethyl-4,5-epoxy-6-methylenemorphinan-3,14-diol;nalmetrene; C21H25NO3; 55096-26-9; JF-1; ORF 11676Nalmefene Hydrochloride 58895-64-0Opioid antagonist
N
O
HO
OH
H2C
Nalorphine na·lor·fën(1) (-)-(5R,6S)-9a-Allyl-4,5-epoxymorphin-7-en-3,6-diol; (2) 17-allyl-17-normorphine; C19H21NO3; 62-67-9�Nalorphine Hydrobromide 1041-90-3Opioid antagonist
N
O
HO
H
HO
CH2
Naloxone na·loks·ön(1) (-)-(5R,14S)-9a-Allyl-4,5-epoxy-3,14-dihydroxymorphinan-6-one; (2) 17-allyl-6-deoxy-7,8-dihydro-14-hydroxy-6-oxo-17-normorphine; C19H21NO4; 465-65-6Naloxone Hydrochloride 51481-60-8; NARCAN
Opioid antagonist
N
O
HO
OH CH2
O
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3-91Naltrexone nal·treks·ön
(5R)-9a-Cyclopropylmethyl-3,14-dihydroxy-4,5-epoxymorphinan-6-one;C20H23NO4; 16590-41-3Naltrexone Hydrochloride 16676-29-2; NALOREX
Opioid antagonist
N
O
HO
OH
O
Nandrolone nan·dro·lön17b-Hydroxyestr-4-en-3-one; C18H26O2; 434-22-0Nandrolone Cyclohexylpropionate 912-57-2; ¨RETARBOLIN
�Nandrolone Decanoate 360-70-3; DECA-DURABOLIN
�Nandrolone Laurate 26490-31-3; ¨LAURABOLIN
�Nandrolone Phenylpropionate 62-90-8; ¨NANDROLIN
Anabolic steroid; androgen
O
H H
Me
H H
H
OH
Nanterinone nan·te·ri·nön6-(2,4-Dimethylimidazol-1-yl)-8-methyl-2(1H)-quinolone; C15H15N3O; 102791-47-9Nanterinone Mesilate 102791-74-2; UK-61260-27Cardiac stimulant
N O
N
NMe
Me
MeH
�Naphazoline na·fä·zö·lën2-(1-Naphthylmethyl)-2-imidazoline; C14H14N2; 835-31-4Naphazoline Hydrochloride 550-99-2�Naphazoline Nitrate 5144-52-5Alpha-adrenoceptor agonist
N
NH
Naphthalophos see Naftalofos
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3-92�Naproxen na·proks·en
(S)-2-(6-Methoxy-2-naphthyl)propionic acid; C14H14O3; 22204-53-1; ̈ EQUIPROXEN;LARAFLEX; NAPROSYN; NAPROTEC*; NYCOPREN
Naproxen Sodium 26159-34-2; SYNFLEX
Analgesic; anti-inflammatory
COOH
H Me
MeO
Narasin na·ra·sin2-[6-[5-(5-Ethyltetrahydro-5-hydroxy-6-methylpyran-2-yl)-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-en-9-yl]-2-hydroxy-1,3-dimethyl-4-oxoheptyl]tetrahydro-3,5-dimethylpyran-2-yl]butyric acid; C43H72O11;55134-13-9; ̈ MONTEBAN
Coccidiostat (veterinary)
OEt
Me
OH
Me
O
OO
O
OMe
OH
Et
MeOHMe
Me
MeMe
HOOC
EtHH H
H
Naratriptan na·ra·trip·tanN-Methyl-2-[3-(1-methylpiperidin-4-yl)indol-5-yl]ethanesulfonamide;C17H25N3O2S;121679-13-8; NARAMIG
Naratriptan Hydrochloride 121679-19-4; GR 85548ASerotonin 5HT1-receptor agonist
N
NMe
SMeHN
O O
H
Natamycin na·ta·mï·sinA polyene antibiotic produced by Streptomyces natalensis; pimaricin; C33H47NO13;7681-93-8; ̈ MYCOPHYT; ̈ PIMAVECORT*Antibiotic
O
O
O
O
COOH
Me
OH
HO
OH
O
H
H H
O OH
NH2OH
Me
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3-93Nateglinide na·te·gli·nïd
N-[(trans-4-Isopropylcyclohexyl)carbonyl]-D-phenylalanine; C19H27NO3; 105816-04-4Hypoglycaemic
HN H
COOH
OPr i
Nealbarbital (nealbarbitone) në·al·bar·bi·tal5-Allyl-5-neopentylbarbituric acid; C12H18N2O3;561-83-1Hypnotic
NH
N OO
O
Me
CH2
MeMe
H
Nebacumab ne·ba·kü·mabImmunoglobulin M (human monoclonal HA-lA anti-endotoxin), disulfide withhuman monoclonal HA-lA k-chain, pentameric dimer; 138661-01-5Immunomodulator
Nebivolol ne·bi·vo·lol(lRS,1¢RS)-1,1¢-[(2RS,2¢SR)-Bis(6-fluorochroman-2-yl)]-2,2¢-iminodiethanol;C22H25F2NO4; 99200-09-6Nebivolol Hydrochloride R67555Beta1-adrenoceptor antagonist
O
F
N
F
OOHH OHH
H H
and enantiomer
H
Nedocromil ne·do·krö·mil9-Ethyl-6,9-dihydro-4,6-dioxo-10-propyl-4H-pyrano[3,2-g]quinoline-2,8-dicarboxylic acid; C19H17NO7; 69049-73-6Nedocromil Calcium 101626-68-0; FPL 59002KCNedocromil Sodium 69049-74-7; RAPITIL; TILADE; TILARIN
Prophylaxis of allergic conditions
N O
O
COOH
Pr nEt
HOOC
O
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3-94Nefazodone ne·fä·zö·dön
2-{3-[4-(3-Chlorophenyl)piperazin-1-yl]propyl)-5-ethyl-2,4-dihydro-4-(2-phenoxyethyl)-1,2,4-triazol-3-one; C25H32ClN5O2; 83366-66-9Nefazodone Hydrochloride 82752-99-6; DUTONIN
Antidepressant
N
NNO
N
N
O
Et
Cl
Nefopam ne·fö·pam(RS)-3,4,5,6-Tetrahydro-5-methyl-1-phenyl-1H-2,5-benzoxazocine; C17H19NO;13669-70-0Nefopam Hydrochloride 23327-57-3; ACUPAN
Analgesic
O
NMe
H
and enantiomer
Nelarabine ne·la·ra·bën2-Amino-9-(b-D-arabinofuranosyl)-6-methoxy-9H-purine; C11H15N5O5; 121032-29-9Antineoplastic
O
OH
N
N
N
N
OMe
H2N
HO
HO
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3-95Nelfinavir nel·fin·a·veer
(3S,4aS,8aS)-N-tert-Butyldecahydro-2-[(2R,3R)-3-(3-hydroxy-o-toluamido)-2-hydroxy-4-(phenylthio)butyl]isoquinoline-3-carboxamide; C32H45N3O4S; 259989-65-8; VIRACEPT
HIV-1 protease inhibitor; antiviral
NH
O
NH
H
OHH
H
S
HO
Me CONHBu t
�NeocinchophenEthyl 6-methyl-2-phenylquinoline-4-carboxylate; C19H17NO2; 485-34-7
N
Me
COOEt
Neomycin në·ö·mï·sinAntimicrobial aminoglycosides produced by selected strains of Streptomyces fradiae;neomycin B is framycetin; 1404-04-2�Neomycin Sulphate 1405-10-3; MINIMS NEOMYCIN; ̈ NEOBIOTIC; NEOMIN; NIVEMYCIN;¨OROJET-N; component in many other proprietary preparationsAntibacterial
Neostigmine (BAN) në·ö·stig·mën3-(Dimethylcarbamoyloxy)trimethylanilinium ion; C12H19N2O2�Neostigmine Bromide 114-80-7�Neostigmine Methylsulphate 51-60-5; ROBINUL NEOSTIGMINE*Anticholinesterase
Me3N O NMe2
O
+
Br_
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3-96Netilmicin ne·til·mï·sin
(1) 4-O-[(2R,3R)-cis-3-Amino-6-aminomethyl-3,4-dihydro-2H-pyran-2-yl]-2-deoxy-6-O-(3-deoxy-4-C-methyl-3-methylamino-b-L-arabinopyranosyl)-1-N-ethylstreptamine; (2) 2-deoxy-6-O-(3-deoxy-4-C-methyl-3-methylamino-b-L-arabinopyranosyl)-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-D-glycero-hex-4-enopyranosyl)-1-N-ethyl streptamine;(3) N 1-ethylsissomicin; C21H41N5O7; 56391-56-1�Netilmicin Sulphate (2:5) 56391-57-2; Sch 20569; NETILLIN
Antibiotic
NH2NHEt
OH
O
O
HO
NHMe OH2N
NH2
O
Me
HO
Netivudine ne·ti·vü·dën1-b-D-Arabinofuranosyl-5-prop-1-ynyluracil; C12H14N2O6; 84588-93-0; 882C87‘Thymidylate kinase mechanism’; antiviral
O
CH3
O
O
N
HN
HO
OH
HO
Netobimin ne·tö·bi·min2-{3-Methoxycarbonyl-2-[2-nitro-5-(propylthio)phenyl]guanidino}ethanesulfonicacid; C14H20N4O7S2; 88255-01-0; ̈ HAPADEX
Anthelmintic (veterinary)
NHCOOMe
SO3HNN
NO2
PrnSH
Neutral Insulin Injection see Insulin Injection
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3-97Nevirapine ne·vîr·ra·pën
11-Cyclopropyl-5,11-dihydro-4-methyl-6H-dipyrido[3,2-b:2¢,3¢-e][1,4]diazepin-6-one; C15H14N4O; 129618-40-2; VIRAMUNE
Antiviral
N
NN N
OMeH
Nialamide nï·al·a·mïdN¢-(2-Benzylcarbamoylethyl)isonicotinohydrazide; C16H18N4O2; 51-12-7Monoamine oxidase inhibitor
N
NN N
O
OH
H H
�Nicametate2-Diethylaminoethyl nicotinate; C12H18N2O2; 3099-52-3
N
ONEt2
O
Nicarbazin (BAN) nï·kar·ba·zin1,3-Bis(4-nitrophenyl)urea—4,6-dimethylpyrimidin-2-ol; C19H18N6O6;330-95-0; ̈ CARBICRAM; ̈ CYCARB; ̈ NICRAZIN
Coccidiostat
O2N
NH
NH
ONO2
• N
NMe OH
Me
Nicardipine nï·kar·di·pën(RS)-2-[Benzyl(methyl)amino]ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate; C26H29N3O6; 55985-32-5Nicardipine Hydrochloride 54527-84-3; CARDENE
Calcium antagonist
N
NO2
MeMe
MeOOCO
N
O MeH
H
and enantiomer
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3-98Nicergoline nï·ser·go·lën
(8R)-10-Methoxy-1,6-dimethylergolin-8-ylmethyl 5-bromonicotinate;C24H26BrN3O3; 27848-84-6Vasodilator
MeH
N
MeN O
HOMeO
N
Br
Niceritrol nï·se·ri·trolPentaerythritol tetranicotinate; C29H24N4O8; 5868-05-3Hypolipidaemic
N N
N
OOO
O
O O
O
N
O
Niclofolan nï·klö·fö·lan5,5¢-Dichloro-3,3¢-dinitrobiphenyl-2,2¢-diol; C12H6Cl2N2O6; 10331-57-4Anthelmintic
OH HO NO2O2N
ClCl
�Niclosamide ni·klö·sa·mïd2¢,5-Dichloro-4¢-nitrosalicylanilide; C13H18Cl2N2O4; 50-65-7�Niclosamide Monohydrate YOMESAN
Anthelmintic
N
NO2ClO
OH
Cl
H
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3-99Nicocodine ni·kö·kö·dën
(1) (-)-(5R,6S)-4,5-Epoxy-3-methoxy-9a-methylmorphin-7-en-6-yl nicotinate; (2)3-O-methyl-6-O-nicotinoylmorphine; C24H24N2O4;3688-66-2Opioid analgesic
NMe
O
MeO
H
O
O
N
Nicodicodine ni·kö·dï·kö·dën(1) (-)-(5R,6S)-4,5-Epoxy-3-methoxy-9a-methylmorphinan-6-yl nicotinate; (2)7,8-dihydro-3-O-methyl-6-O-nicotinoylmorphine; C24H26N2O4; 808-24-2Antitussive
NMe
O
MeO
H
O
O
N
�Nicofuranose ni·kö·fûr·ra·nösb-D-Fructofuranose 1,3,4,6-tetranicotinate; C30H24N4O10; 15351-13-0Vasodilator
O
OR
ROOH
OR
RO
N
CO
R =
Nicomorphine ni·kö·mor·fën(1) (-)-(5R,6S)-4,5-Epoxy-9a-methylmorphin-7-en-3,6-diyl dinicotinate; (2) 3,6-di-O-nicotinoylmorphine; C29H25N3O5; 639-48-5Opioid analgesic
NMe
O
O
H
O
N
N
O
O
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3-100Nicorandil ni·kö·ran·dil
N-[2-(Nitro-oxy)ethyl]nicotinamide; C8H9N3O4; 65141-46-0; IKOREL
Antianginal
N
NO
NO2
O
H
Nicotinyl Alcohol (BAN) ni·kö·ti·nïl3-Pyridylmethanol; C6H7NO; 100-55-0Nicotinyl Alcohol Tartrate 6164-87-0; RONICOL
Vasodilator
N
CH2OH
Nicoumalone see Acenocoumarol
�Nifedipine nï·fe·di·pënDimethyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate;C17H18N2O6; 21829-25-4; ADALAT; ADIPINE; ANGIOPINE; BETA-ADALAT*; CARDILATE;CORACTENT; FORTIPINE; NIFENSAR; TENIF*; TENSIPINE; UNIPINE
Calcium antagonist
HN MeMe
MeOOC COOMe
NO2
Nifenazone nï·fe·na·zönN-(2,3-Dimethyl-5-oxo-1-phenyl-3-pyrazolin-4-yl)nicotinamide; C17H16N4O2; 2139-47-1Analgesic; anti-inflammatory
N
NN
O
NO
H
Me Me
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3-101Nifuratel nï·fûr·ra·tel
5-Methylthiomethyl-3-(5-nitrofurfurylideneamino)-2-oxazolidone; C10H11N3O5S;4936-47-4Antiprotozoan
ON
O2N
N
OO
SCH3
Nifuroquine nï·fûr·rö·kwën4-(5-Nitro-2-furyl)quinoline-2-carboxylic acid 1-oxide; C14H8N2O6;57474-29-0; ̈ ABIMASTEN-100Antibacterial
O
N
O2N
COOH
O
Nifursol nï·fûr·sol3,5-Dinitro-2¢-(5-nitrofurfurylidene)salicylohydrazide; C12H7N5O9;16915-70-1; ̈ SALFURIDE
Antiprotozoan
ON
O2N
N
O OH
NO2
NO2
H
Nifurtimox nï·fûr·ti·moks(RS)-Tetrahydro-3-methyl-4-(5-nitrofurfurylideneamino)-1,4-thiazine 1,1-dioxide;C10H13N3O5S; 23256-30-6Antiprotozoan
SMe
N
O2NN
O
H
O
Oand enantiomer
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3-102�Nikethamide ni·ke·tha·mïd
N,N-Diethylpyridine-3-carboxamide; C10H14N2O; 59-26-7Central nervous system stimulant
N
CONEt2
Nilestriol (nylestriol) nï·lës·trë·ol3-Cyclopentyloxy-19-nor-17a-pregna-1,3,5(10)-trien-20-yne-16a,17b-diol;C25H32O3; 39791-20-3Oestrogen
H
H
H
OH
CHOH
Me
O
Nilprazole nil·pra·zôl4-{[1-(2-Benzoylethyl)benzimidazol-2-yl]methyl}piperazin-1-yl-N-isopropylacetamide; C26H33N5O2; 60662-19-3; 73442 MDGastric antisecretory
N
N
O
N
NNHPr i
O
Niludipine nï·lü·di·pënBis(2-propoxyethyl) 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate; C25H34N2O8; 22609-73-0; BAY a 7168Calcium antagonist
HN
NO2
MeMe
OO
O
CH3OO
H3C
O
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3-103Nilutamide nï·loo·ta·mïd
5,5-Dimethyl-3-(a,a,a-trifluoro-4-nitro-m-tolyl)-imidazolidine-2,4-dione;C12H10F3N3O4; 63612-50-0Antineoplastic
NNH
CF3
O2N
Me Me
O
O
Nimesulide nï·me·sü·lïd4¢-Nitro-2¢-phenoxymethanesulfonanilide; C13H12N2O5S; 51803-78-2;R 805Analgesic; anti-inflammatory
O
NO2
NHSO2CH3
Nimodipine ni·mö·di·pën(RS)-Isopropyl 2-methoxyethyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)-pyridine-3,5-dicarboxylate; C21H26N2O7; 66085-59-4; NIMOTOP
Calcium antagonist
and enantiomer
HN MeMe
Pr i OOCH
OOMe
O
NO2
�Nimorazole nï·mor·ra·zôl1-(2-Morpholinoethyl)-5-nitroimidazole; nitrimidazine; C9H14N4O3;6506-37-2Antiprotozoan
N
NN
ONO2
Niridazole nï·ri·da·zôl1-(5-Nitro-1,3-thiazol-2-yl)imidazolidin-2-one; C6H6N4O3S; 61-57-4Anthelmintic
NH
NS
N
O2N
O
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3-104Nisoldipine nï·sol·di·pën
(RS)-Isobutyl methyl 1,4-dihydro-2,6-dimethyl-4-(2-nitrophenyl)pyridine-3,5-dicarboxylate; C20H24N2O6; 63675-72-9; SYSCOR
Calcium antagonist
HN MeMe
MeOOC
NO2
COOBu iH
and enantiomer
Nitazoxanide nï·ta·zoks·a·nïd2-(5-Nitro-1,3-thiazol-2-ylcarbamoyl)phenyl acetate; C12H9N3O5S;55981-09-4Treatment of diarrhoea in AIDS
N
S
N
O2N
O OAc
H
�Nitrazepam nï·trä·ze·pam1,3-Dihydro-7-nitro-5-phenyl-1,4-benzodiazepin-2-one; C15H11N3O3;146-22-5; MOGADON; REMNOS; SOMNITE
Hypnotic
N
NO2N
OH
Nitrefazole nï·tref·a·zôl2-Methyl-4-nitro-1-(4-nitrophenyl)imidazole; C10H8N4O4; 21721-92-6;EMD 15 700Treatment of alcoholism
N
N
Me
O2N
NO2
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3-105Nitrendipine nï·tren·di·pën
(RS)-Ethyl methyl 1,4-dihydro-2,6-dimethyl-4-(3-nitrophenyl)pyridine-3,5-dicarboxylate; C18H20N2O6; 39562-70-4; BAY e 5009Calcium antagonist
and enantiomer
N MeMe
MeOOCH
NO2
COOEt
H
Nitrocefin (BAN) nï·trö·së·fin(7R)-3-[(E)-2,4-Dinitrostyryl]-7-(2-thienylacetamido)-3-cephem-4-carboxylic acid;C21H16N4O8S2; 41906-86-9Nitrocefin Sodium 87/312Diagnostic reagent
�Nitrofurantoin nï·trö·fûr·ran·tö·in1-(5-Nitrofurfurylideneamino)hydantoin; C8H6N4O5; 67-20-9; FURADANTIN;MACROBID; MACRODANTIN; URANTOIN
Antibacterial
ON
O2N
N NH
O
O
�Nitrofurazone nï·trö·fûr·ra·zön5-Nitro-2-furaldehyde semicarbazone; nitrofural (pINN); C6H6N4O4;59-87-0; ̈ AUROID*; ̈ DERMOBION*; ̈ NITROCETIN-A*; ̈ TROPHEN*Antibacterial; topical antiprotozoan
ON
O2N
N NH2
O
H
Nitroscanate nï·tros·ka·nät4-(4-Nitrophenoxy)phenyl isothiocyanate; C13H8N2O3S; 19881-18-6; ¨LOPATOL;¨TROSCAN
Anthelmintic
O
O2N NCS
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3-106Nitrovin (BAN) nï·trö·vin
(1) Bis[2-(5-nitro-2-furyl)vinyl]methylenehydrazinoformamidine; (2) 1,5-bis(5-nitro-2-furyl)penta-1,4-dien-3-one amidinohydrazone; C14H12N6O6; 804-36-4;¨PENTAZONE
Nitrovin Hydrochloride 2315-20-0; ¨PAYZONE
Antibacterial
OON
NH
H2N NH
NO2O2N
�Nitroxinil (nitroxynil) nï·troks·ë·nil4-Hydroxy-3-iodo-5-nitrobenzonitrile; C7H3IN2O3; 1689-89-0Nitroxinil Eglumine 27917-82-4; ¨GAPEX; ¨TRODAX
Anthelmintic
CN
I
OH
O2N
Nitroxoline nï·troks·ö·lën5-Nitroquinolin-8-ol; C9H6N2O3; 4008-48-4Antibacterial
N
OH
NO2
Nitroxynil see Nitroxinil
Nivimedone nï·vi·me·dön5,6-Dimethyl-2-nitroindan-1,3-dione; C11H9NO4; 49561-92-4Nivimedone Sodium BRL 10833Antiallergic
Me
Me
O
O
NO2
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3-107Nizatidine nï·za·ti·dën
(1) N-[2-(2-Dimethylaminomethyl-1,3-thiazol-4-ylmethylthio]ethyl-N¢-methyl-2-nitrovinylidenediamine; (2) 4-[2-(1-methylamino-2-nitro-vinylamino)ethylthiomethyl]-1,3-thiazol-2-ylmethyl(dimethyl)amine; C12H21N5O2S2;76963-41-2; AXID; ZINGA
Histamine H2-receptor antagonist
HN
S
O2N
NHMe S
NNMe2
Noberastine no·be·ras·tën3-(5-Methylfurfuryl)-3H-imidazo[4,5-b]pyridin-2-yl(4-piperidyl)amine;C17H21N5O; 110588-56-2Noberastine Maleate (1:2) R 72075Histamine H1-receptor antagonist
O
N
NN Me
NH
N
Nomifensine no·mi·fen·sën(RS)-1,2,3,4-Tetrahydro-2-methyl-4-phenylisoquinolin-8-ylamine; C16H18N2;24526-64-5Nomifensine Maleate 32795-47-4Antidepressant
NMe
NH2
H
and enantiomer
Nonabine non·a·bën7-(1,2-Dimethylheptyl)-2,2-dimethyl-4-(4-pyridyl)-2H-chromen-5-ol; C25H33NO2;16985-03-8; BRL 4664Antiemetic
O
N
Me
Me
OH
Me
Me
H3C*
mixture of stereoisomers
*
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3-108Nonacog Alfa non·a·kog al·fa
Blood coagulation factor IX (human), glycoform a; 113478-33-4Antihaemophilic
Nonoxinol no·noks·i·nola-(4-Nonylphenyl)-w-hydroxypoly(oxyethylene)Each nonoxinol name is followed by a number indicating the approximate numberof oxyethylene groups present, eg nonoxinol 4, nonoxinol 9, and the individualchemical names may contain a specific numerical syllable for the same purpose;DELFEN; DOUBLE-CHECK; DURAGEL; GYNOL II; ORTHO-CREME; ORTHO-FORM
Pharmaceutical aids; spermatocides
H19C9
OOH
n
�Noracymethadol1-Ethyl-4-methylamino-2,2-diphenylpentyl acetate (a-form); C22H29NO2; 50572-73-7
HMeHN
H3CH OAc
CH3* *
mixture of stereoisomers
Noradrenaline / Norepinephrine nor·a·dre·na·lën/nor·e·pi·ne·frën(R)-2-Amino-1-(3,4-dihydroxyphenyl)ethanol; C8H11NO3; 51-41-2�Noradrenaline Acid Tartrate / Norepinephrine Acid Tartrate norepinephrinebitartrate (USAN);51-40-1 (anhydrous); 69815-49-2 (monohydrate); LEVOPHED
�Noradrenaline Hydrochloride / Norepinephrine Hydrochloride 329-56-6Alpha-adrenoceptor agonist
NH2HO
HO
OHH
Norbudrine (norbutrine) nor·bü·drën2-Cyclobutylamino-1-(3,4-dihydroxyphenyl)ethanol; C12H17NO3; 15686-81-4Bronchodilator
NHO
HO
OHH H
and enantiomer
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3-109Norcodeine nor·kö·dën
(1) (-)-(5R,6S)-4,5-Epoxy-3-methoxymorphin-7-en-6-ol; (2) 3-O-methyl-17-normorphine; C17H19NO3; 467-15-2Opioid analgesic
NH
O
MeO
H
HO
�Norethandrolone17b-Hydroxy-19-nor-17a-pregn-4-en-3-one; C20H30O2; 52-78-8
O
H
H
H
H
Me Et
OH
�Norethisterone nor·e·thi·ste·rön17b-Hydroxy-19-nor-17a-pregn-4-en-20-yn-3-one; norethindrone (USAN);C20H26O2; 68-22-4; BINOVUM*; BREVINOR*; CLIMAGEST*; CLIMESSE*; EVOREL-PAK;MENOPHASE*; MENZOL; MICRONOR; NORIDAY; NORIMIN*; ORTHO-NOVIN*; OVYSMEN*;PRIMOLUT N; UTOVLAN*�Norethisterone Acetate Norethandrone Acetate (USAN) 51-98-9; ELLEST DUET*;ESTRACOMBI*; ESTRAPAK*; KLIOFEM*; LOESTRIN 20*; NORINYL-1*; SYNPHASE*; TRINOVUM*;TRISEQUENS*;Norethisterone Enanthate NORISTERAT
Progestogen
O
H
H
H
Me OH
CHH
�Noretynodrel (norethynodrel)17b-Hydroxy-19-nor-17a-pregn-5(10)-en-20-yn-3-one; C20H26O2;68-23-5
O
H
H
H
Me OH
CH
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3-110Norfloxacin nor·floks·a·sin
1-Ethyl-6-fluoro-1,4-dihydro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid;C16H18FN3O3; 70458-96-7; UTINOR
Antibacterial
NN
HN
COOH
O
Et
F
Norflurane nor·flûr·rän1,1,1,2-Tetrafluoroethane; C2H2F4; 811-97-2Anaesthetic (inhalation)
FH
F F
H F
Norgestimate nor·jes·ti·mät13b-Ethyl-3-hydroxyimino-18,19-dinor-17a-pregn-4-en-20-yn-17b-yl acetate;C23H31NO3; 35189-28-7 CILEST*Progestogen
N
H
H
H
Et OAc
CH
HO
H
�Norgestomet11b-Methyl-3,20-dioxo-19-norpregn-4-en-17a-yl acetate; C23H32O4;25092-41-5; CRESTAR
O
H
H
H
MeOAc
H
CH3O
Me
�Norgestrel nor·jes·trelrac-13b-Ethyl-17b-hydroxy-18,19-dinor-17a-pregn-4-en-20-yn-3-one;DL-norgestrel; dl-norgestrel; C21H28O2; 6533-00-2; CYCLO-PROGYNERVA*; NEOGEST;PREMPAK*; SCHERING PC4Progestogen
O
H
H
H
Et OH
CHH
and enantiomer
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3-111Norletimol nor·le·ti·mol
a-Benzylimino-o-cresol; C14H13NO; 886-08-8Antirheumatic
N
OH
Norlevorphanol nor·le·vor·fa·nol(-)-Morphinan-3-ol; C16H21NO; 1531-12-0Opioid analgesic
NH
HO
H
Normethadone nor·me·tha·dön6-Dimethylamino-4,4-diphenylhexan-3-one; C20H25NO; 467-85-6Opioid analgesic
NMe2CO
CH3
Normorphine nor·mor·fën(-)-(5R,6S)-4,5-Epoxymorphin-7-en-3,6-diol; C16H17NO3; 466-97-7Opioid analgesic
NH
O
HO
H
HO
Norpipanone nor·pi·pa·nön4,4-Diphenyl-6-piperidinohexan-3-one; C23H29NO; 561-48-8Opioid analgesic
NCO
CH3
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3-112Nortriptyline nor·trip·ti·lën
3-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylidene)propyl(methyl)amine;C19H21N; 72-69-5�Nortriptyline Hydrochloride 894-71-3; ALLEGRON; MOTIPRESS*; MOTIVAL*Antidepressant
NHMe
Nosantine nö·san·tën9-{(1R*)-1-[(S*)-1-Hydroxyethyl]heptyl}hypoxanthine; C14H22N4O2;76600-30-1; NPT 15392Immunoregulator
HN
NN
N
CH3
CH3HO
HH
O
and enantiomer
�Noscapine nos·ka·pën(3S)-6,7-Dimethoxy-3-[(5R)-5,6,7,8-tetrahydro-4-methoxy-6-methyl-1,3-dioxolo[4,5-g]isoquinolin-5-yl]phthalide; l-a-narcotine; C22H23NO7;128-62-1�Noscapine Hydrochloride 912-60-7Antitussive
O
NMeO
O
HH
OMeO
OMe
MeO
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3-113Nosiheptide nö·si·hep·tïd
A peptide antibiotic obtained from cultures of Streptomyces actuosus 40037 or thesame substance obtained by any other means; 56377-79-8Antibiotic
N
SN
S
N
N
N
S
OHN
HON
O
S
N
S
N
SHNN
CH2OO
OH
O
H3C
Me
OH NNH2
O CH2
O
OMe
O
H
H
H
Novobiocin nö·vö·bï·ö·sinAn antimicrobial substance produced by Streptomyces niveus and S. spheroides orrelated organisms; 4-hydroxy-3-[4-hydroxy-3-(3-methylbut-2-enyl)benzamido]-8-methylcoumarin-7-yl 3-O-carbamoyl-5,5-di-C-methyl-a-L-lyxopyranoside;C31H36N2O11; 303-81-1Novobiocin Sodium 1476-53-5; ̈ ALBADRY; ̈ NOVOMAST*; ̈ TETRA-DELTA*Antibacterial
O O
NH
OHOH
Me
O
H2N O
Me
MeMeO
OH
O
OO
CMe2
Noxiptyline (noxiptiline) noks·ip·ti·lën2-(10,11-Dihydro-5H-dibenzo[a,d]cyclohepten-5-ylideneamino-oxy)-ethyldimethylamine; C19H22N2O; 3362-45-6Noxiptiline Hydrochloride BAY 1521Antidepressant
NO
NMe2
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3-114Noxytiolin (noxythiolin) noks·ë·tï·ö·lin
1-Hydroxymethyl-3-methyl-2-thiourea; C3H8N2OS; 15599-39-0; NOXYFLEX
Antimicrobial
HO N NHMe
S
H
Nufenoxole nü·fe·noks·ôl2-[3-(2-Azabicyclo[2.2.2]octan-2-yl)-1,1-diphenylpropyl]-5-methyl-1,3,4-oxadiazole; C25H29N3O; 57726-65-5; SC 27166Antidiarrhoeal
N
N
N
O
Me
Nupafant nü·pa·fant(S)-N-(1-Ethoxymethyl-3-methylbutyl)-N-methyl-a-(2-methyl-1H-imidazolo[4,5-c]pyridin-1-yl)-p-toluenesulfonamide; C23H32N4O3S;139133-27-0; BB-960Nupafant Hydrochloride 144736-31-2; BB-2113Platelet activating factor antagonist
N N
NMe
S
Me
Me
MeN
OOOEt
H
H
Nylestriol see Nilestriol
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3-115�Nystatin nï·stat·in
A mixture of antifungal polyenes produced by Streptomyces noursei;Nystatin A1 is 19-(3-amino-3,6-dideoxy-b-D-mannopyranosyloxy)-16-carboxy-3,5,7,10,11,15,17,35-octahydroxy-34,36-dimethyl-13-oxo-octatriaconta-20,22,24,26,30,32-hexaen-37-olide; 1400-61-9; ¨NYSTAMONT; NYSTAN; componentin many other proprietary preparations
O
O OH OH OH
OH
OH
OHOH
COOHO
H
Me
HO
Me
Me
O
O
Me
HO
NH2 OH
Ocaperidone o·ka·pe·ri·dön3-(2-[4-(6-Fluoro-1,2-benzoxazol-3-yl)piperidino]ethyl)-2,9-dimethylpyrido[1,2-a]pyrimidin-4-one; C24H25FN4O2; 129029-23-8; R79598Antipsychotic
N
N
N
ON
O
Me
Me
F
Octacosactrin see Tosactide
Octafonium Chloride (octaphonium chloride) ok·ta·fö·në·umBenzyldiethyl-2-[4-(1,1,3,3-tetramethylbutyl)phenoxy]ethylammonium chloride;phenoctide; C27H42ClNO; 15687-40-8; GERMOLENE
Anti-infective
+
Cl_
Et EtMe
MeMe
NO
Me
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3-116Octatropine Methylbromide ok·ta·trö·pën
(1R,3r,5S)-8-Methyl-3-(2-propylvaleryloxy)tropanium bromide; anistropinemethylbromide (USAN); C17H32BrNO2; 80-50-2Anticholinergic
+
and enantiomer at C*
*
NMe
O
O
H
Me
CH3
CH3Br
_
�Octaverine6,7-Dimethoxy-1-(3,4,5-triethoxyphenyl)isoquinoline; C23H27NO5;549-68-8
N
MeO
MeO
EtO
OEt
OEt
Octenidine ok·te·ni·dën1,1¢,4,4¢-Tetrahydro-N,N¢-dioctyl-1,1¢-decamethylenedi-(4-pyridylideneamine);C36H62N4; 71251-02-0; WIN 41464Octenidine Hydrochloride 70775-75-6; WIN 41464-2Octenidine Saccharin 86767-75-1; WIN 41464-6Antiseptic
N (CH2)10N(CH2)7 N N (CH2)7 CH3H3C
![Page 479: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/479.jpg)
3-117Octocog Alfa
Recombinant human antihaemophilic factor VIII (without von Willebrand factor)derived from a cloned human factor VIII gene; factor VIII (rDNA); KOGENATE;MONOCLATE-P; RECOMBINATE
AntihaemophilicFor labelling purposes the following three-letter code, to indicate the method of
production, is approved:(bhk) produced from genetically engineered baby hamster kidney cells
�Octoxinol ok·toks·i·nola-[4-(1,1,3,3-Tetramethylbutyl)phenyl]-w-hydroxypoly(oxyethylene)Each octoxinol name is followed by a number indicating the approximate number ofoxyethylene groups present eg octoxino 9 and octoxinol 10, and the individualchemical names may contain a specific numerical syllable for the same purposePharmaceutical aids; spermatocides
OOH
Me
MeMe
Me Me
MeMe
n
Octreotide ok·trë·ö·tïd2-(D-Phenylalanyl-L-cystyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-N-(2R,3R)-1,3-dihydroxybutyl]-L-cystinamide; C49H66N10O10S2; 83150-76-9; SMS 201-995Octreotide Acetate; SANDOSTATIN
Somatostatin analogue; treatment of neuroendocrine tumours and acromegaly
CH3
OH
H
OHHD-Phe_Cys_Phe_D-Trp_Lys_Thr_Cys_NH
Oestradiol see Estradiol
Oestriol see Estriol
Oestrone see Estrone
Ofloxacin ö·floks·a·sin(±)-9-Fluoro-2,3-dihydro-3-methyl-10-(4-methylpiperazin-1-yl)-7-oxo-7H-pyrido[1,2,3-de][1,4]benzoxazine-6-carboxylic acid; C18H20FN3O4; 82419-36-1;EXOCIN; TARIVID
Antibacterial
NN
MeN O
F
Me
O
COOH
H
and enantiomer
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3-118Olaflur o·la·flûr
2,2¢-{3-[N-(2-Hydroxyethyl)octadecylamino]propylimino}diethanoldihydrofluoride; C27H58N2O3,2HF; 6818-37-7; 17671-49-1 (base); GA 297Prophylaxis of dental caries
NH3C[ CH2] 17
HO OH
OHN ,2HF
Olanzapine ö·lan·za·pën2-Methyl-4-(4-methylpiperazin-1-yl)-10H-thieno[2,3-b][1,5]benzodiazepine;C17H20N4S; 132539-06-1; ZYPREXA
Antipsychotic
N
N S Me
N
NMe
H
Olaquindox o·la·kwin·doks2-(2-Hydroxyethylcarbamoyl)-3-methylquinoxaline 1,4-dioxide; C12H13N3O4;23696-28-8; ̈ ENTERODOX
Antibacterial
N
N
NOH
Me
OO
O
H
Oleandomycin ö·lë·an·dö·mï·sinAn antibiotic produced by certain strains of Streptomyces antibioticus;(2R,3S,4R,5S,6S,8R,10R,11S,12R,13R)-3-(2,6-Dideoxy-3-O-methyl-a-L-arabino-hexopyranosyloxy)-8,8-epoxymethano-11-hydroxy-2,4,6,10,12,13-hexamethyl-9-oxo-5-(3,4,6-trideoxy-3-dimethylamino-b-D-xylo-hexopyranosyloxy)tridecan-13-olide; C35H61NO12; 3922-90-5
O
EtMe
HO
Me
O Me
Me
O
NMe2
Me
OH
O
O
HO
Me
OMe
Me
O
O
MeO
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3-119Oletimol ö·le·ti·mol
2-[1-(Benzylimino)ethyl]phenol; C15H15NO; 5879-67-4Antirheumatic
N
Me
OH
Olsalazine ol·sa·la·zën5,5¢-Azodisalicylic acid; C14H10N2O6; 15722-48-2; CI Mordant yellow 5Olsalazine Sodium DIPENTUM
Anti-inflammatory
N NHO
HOOC
OH
COOH
Omapatrilat ö·ma·pa·tri·lat(4S,7S,10aS)-Octahydro-4-[(S)-3-phenyl-2-sulfanylpropanamido]-5-oxo-7H-pyrido[2,1-b][1,3]thiazepine-7-carboxylic acid; C19H24N2O4S2; 167305-00-2
ACE- and endopeptidase-inhibitor; antihypertensive
N
S
HN
SHH
H
H COOH
O
OH
�Omega-3 Marine Triglycerides (BAN)A mixture of the triglycerides of the fatty acids from marine fish containing theequivalent of about 18% of eicosapenta-5,8,11,14,17-enoic acid and 12% ofdocosahexa-4,7,10,13,16,19-enoic acid; MAXEPA
Reduction of plasma triglycerides
�Omeprazole ö·me·pra·zôl5-Methoxy-2-(4-methoxy-3,5-dimethyl-2-pyridylmethylsulfinyl)benzimidazole;C17H19N3O3S; 73590-58-6; LOSEC
�Omeprazole Sodium 95510-70-6Treatment of peptic ulcer
NH
N S
NMe
OMe
O
MeO
Me
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3-120Ondansetron on·dan·se·tron
(RS)-1,2,3,9-Tetrahydro-9-methyl-3-(2-methylimidazol-1-ylmethyl)carbazol-4-one;C18H19N3O; 99614-02-5Ondansetron Hydrochloride 103639-04-9; ZOFRAN
5HT3-Serotonin antagonist
N
NN
O Me
Me
H
and enantiomer
Opebacan ö·peb·a·kan132-L-Alanine-1–193-bactericidal/permeability-increasing protein (human); 206254-79-7; rBPI-21;
Bacterial endotoxin binder
opebacan has the following amino acid sequence:VNPGVVVRIS QKGLDYASQQ GTAALQKELK
RIKIPDYSDS FKIKHLGKGH YSFYSMDIRE
GQLPSSQISM VPNVGLKFSI SNANIKISGK
WKAQKRFLKM SGNFDLSIEG MSISADLKLG
SNPTSGKPTI TASSCHSSIN SVHVHISKSK
VGWLIQLFHK KIESALRNKM NSQVCEKVTN
SVSSELQPYF QTL
Opipramol ö·pi·pra·mol2-[4-(3-5H-Dibenz[b,f]azepin-5-ylpropyl)piperazin-1-yl]ethanol; C23H29N3O; 315-72-0Opipramol Hydrochloride 909-39-7Antidepressant
N
N
NOH
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3-121Orciprenaline or·si·pren·a·lën
1-(3,5-Dihydroxyphenyl)-2-isopropylaminoethanol; C11H17NO3; 586-06-1�Orciprenaline Sulphate metaproterenol sulfate (USAN); 5874-97-5; ALUPENT
Beta-adrenoceptor agonist
NHPr iOHH
OH
HO
and enantiomer
Orgotein or·gö·tënA group of water-soluble metalloprotein congeners isolated from liver, red bloodcells and other mammalian tissues; 9016-01-7; ¨PALOSEIN
Anti-inflammatory
Orlistat or·li·stat(S)-1-[(2S,3S)-3-Hexyl-4-oxo-oxetan-2-ylmethyl]dodecyl N-formyl-L-leucinate;C29H53NO5; 96829-58-2; XENICAT
Pancreatic lipase inhibitor; treatment of obesity
H
H3C[ CH2]10
O
N
O
O
CH3H3C
H OO
[ CH2] 5CH3
Orotic Acid o·ro·tik1,2,3,6-Tetrahydro-2,6-dioxopyrimidine-4-carboxylic acid; C5H4N2O4;65-86-1Nutritional supplement
NH
N OO
COOH
H
Orphenadrine or·fe·na·drënDimethyl-2-(2-methylbenzhydryloxy)ethylamine; C18H23NO; 83-98-7Orphenadrine Citrate 4682-36-4; NORFLEX
�Orphenadrine Hydrochloride 341-69-5; BIORPHEN; DISIPAL
Anticholinergic
ONMe2
Me
H
and enantiomer
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3-122�Ostreogrycin
Antimicrobial substances produced by Streptomyces ostreogriseus; certain componentsare identical with some constituents of mikamycin, pristinamycin and virginiamycin;11006-76-1
Otilonium Bromide o·ti·lö·në·um brö·mïdDiethyl(methyl){2-[4-(2-octyloxybenzamido)benzoyloxy]ethyl}ammoniumbromide; C29H43BrN2O4; 26095-59-0; SP63Antispasmodic
N
ONEt2
O(CH2)7CH3
O
O
H
Me
+ Br_
Ovandrotone Albumin ö·van·drö·tön al·bü·minPentadecakis- to pentatriacontakis[3-(3,17-dioxoandrost-4-en-7a-ylthio)-propionyl]albumin, [human serum]; GR 33207Ovine fecundity
O
Me
H
H
H
Me O
SHSA
O
n
HSA = Human Albmin
Ox Bile (BAN)An alcoholic extract of ox bile reduced by evaporation and containing bile salts;ENZYPAN*
Oxacillin oks·a·si·lin(6R)-6-(5-Methyl-3-phenyl-1,2-oxazole-4-carboxamido)penicillanic acid;C19H19N3O5S; 66-79-5Antibacterial
HN
O
HH
Me
Me
COOHH
S
OO N
N
Me
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3-123Oxaliplatin oks·a·li·pla·tin
[(1R,2R)-1,2-Cyclohexanediamine-N,N¢][oxalato(2-)]platinum; C8H14N2O4Pt;61825-94-3; ELOXATIN
Antineoplastic
NH2
NH2
Pt
H
HO
OO
O
�Oxamniquine oks·am·ni·kwën1,2,3,4-Tetrahydro-2-isopropylaminomethyl-7-nitro-6-quinolylmethanol;C14H21N3O3; 21738-42-1Anthelmintic
NNHPr iO2N
HO
H
Oxandrolone oks·an·dro·lön17b-Hydroxy-17a-methyl-2-oxa-5a-androstan-3-one; C19H30O3; 53-39-4Anabolic steroid; androgen
O
O
Me
H
H
H
H
Me Me
OH
Oxantel oks·an·tel(E)-b-(1,4,5,6-Tetrahydro-1-methylpyrimidin-2-yl)styren-3-ol; C13H16N2O; 36531-26-7Oxantel Embonate 42408-84-4Anthelmintic
N
N
OH
Me
Oxaprozin oks·a·prö·zin3-(4,5-Diphenyl-1,3-oxazol-2-yl)propionic acid; C18H15NO3; 21256-18-8Analgesic; anti-inflammatory
N
O COOH
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3-124�Oxatomide oks·a·tö·mïd
1-[3-(4-Benzhydrylpiperazin-1-yl)propyl]-1,3-dihydrobenzimidazol-2-one;C27H30N4OProphylaxis of allergic conditions
HN
N N
NO
�Oxazepam oks·ä·ze·pam(RS)-7-Chloro-1,3-dihydro-3-hydroxy-5-phenyl-1,4-benzodiazepin-2-one;C15H11ClN2O2; 604-75-1; ABBOXAPAM; LEDERPAM; OXANID
Anxiolytic
N
NCl
O
OHH
H
and enantiomer
Oxcarbazepine oks·kar·bä·ze·pën10,11-Dihydro-10-oxo-5H-dibenz[b,f]azepine-5-carboxamide; C15H12N2O2; 28721-07-5Anticonvulsant
N
CONH2
O
Oxedrine oks·e·drën(RS)-1-(4-Hydroxyphenyl)-2-(methylamino)ethanol; C9H13NO2; 94-07-5Oxedrine Tartrate 16589-24-5Sympathomimetic
HO
NHMeH OH
and enantiomer
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3-125Oxeladin oks·e·la·din
2-(2-Diethylaminoethoxy)ethyl 2-ethyl-2-phenylbutyrate; C20H33NO3;468-61-1Antitussive
OO
EtEt
O
NEt2
Oxerutins (BAN) oks·ë·roo·tinsA mixture of 5 different O-(b-hydroxyethyl) rutosides, not less than 45% of whichis troxerutin; PAROVEN
Treatment of venous disorders
�Oxetacaine (oxethazaine) oks·e·ta·kän2,2¢-(2-Hydroxyethylimino)bis[N-(a,a-dimethylphenethyl)-N-methylacetamide];C28H41N3O3; 126-27-6; MUCAINE*Local anaesthetic
N
NHO N
OMeMe
O
Me
Me MeMe
�Oxfendazole oks·fen·da·zôlMethyl 5-(phenylsulfinyl)-1H-benzimidazol-2-ylcarbamate; C15H13N3O3S; 53716-50-0; ̈ AUTOWORM; ̈ BOVEX; ̈ OXFENIL; ̈ PARAFEND; ̈ SYNANTHIC; ̈ SYSTAMEX
Anthelmintic
S
N
N
O
NHCOOMeH
Oxfenicine oks·fe·ni·sën(S)-2-(4-Hydroxyphenyl)glycine; C8H9NO3; 32462-30-9; UK-25842Treatment of ischemic heart disease
COOH
HO
NH2H
Oxibendazole oks·ë·ben·da·zôlMethyl 5-propoxy-1H-benzimidazol-2-ylcarbamate; C12H15N3O3;20559-55-1; ̈ EQUIDIN; ̈ EQUITAC; ̈ LINCOLN; ̈ LODITAC
Anthelmintic
N
N NHCOOMe
OH3C
H
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3-126Oxiconazole oks·ë·ko·na·zôl
2¢,4¢-Dichloro-2-(imidazol-1-yl)acetophenone (Z)-O-(2,4-dichlorobenzyl)oxime;C18H13Cl4N3O; 64211-45-6; Ro 13-8996/000Oxiconazole Nitrate 64211-46-7; Ro 13-8996/001Antifungal
NO
N
N
Cl
Cl
ClCl
Oxidronic Acid oksë·dro·nik(Hydroxymethylene)diphosphonic acid; CH6O7P2; 15468-10-7Sodium Oxidronate 14255-61-9 (2Na)Diagnostic aid to bone visualisation
P
O
OH
OHP
O
OH
HO CH
OH
Oxipurinol (oxypurinol) oks·ë·pûr·ri·nol1H-Pyrazolo[3,4-d]pyrimidine-4,6-diol; C5H4N4O2; 2465-59-0Xanthine oxidase inhibitor
N
NN
N
OH
HOH
Oxiracetam oks·ë·ra·se·tam(1) (RS)-2-(4-Hydroxy-2-oxopyrrolidin-1-yl)acetamide; (2) (RS)-N-carbamoylmethyl-3-hydroxybutane-4-lactam; C6H10N2O3; 62613-82-5;CGP 21690ECerebral stimulant
NNH2
OO
HOH
and enantiomer
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3-127Oxitropium Bromide oks·ë·trö·pë·um
(1R,3s,5S,6R,7S,8r)-8-Ethyl-3-[(S)-tropoyloxy]-6,7-epoxytropanium bromide;C19H26BrNO4; 30286-75-0; OXIVENT
Anticholinergic
NMe
O
O
Et
OH
H
OBr
_
+
Oxmetidine oks·me·ti·dën2-[2-(5-Methylimidazol-4-ylmethylthio)ethylamino]-5-piperonylpyrimidin-4-(1H)-one; C19H21N5O3S; 72830-39-8; SK&F 92994Histamine H2-receptor antagonist
O
O
N
HN
HN
S
O
N
NH
Me
�Oxolinic Acid oks·ö·lin·ik5-Ethyl-5,8-dihydro-8-oxo-1,3-dioxolo[4,5-g]quinoline-7-carboxylic acid;C13H11NO5; 14698-29-4; ̈ AQUALINIC; ̈ AQUINOX
Antibacterial
O
O
N
O
COOH
Et
Oxoprostol oks·ö·prost·ol(1) trans-2-(7-Hydroxyheptyl)-3-(3-oxo-4-phenoxybutyl)cyclopentanone; (2) trans-1-hydroxy-16-phenoxy-w-tetranorprostane-9,15-dione; C22H32O4; 69648-40-4;M&B 33153Prostanoid gastric antisecretory
O
H
H
OOH
O
and enantiomer
Oxpentifylline see Pentoxifylline
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3-128Oxprenolol oks·pren·o·lol
1-o-Allyloxyphenoxy-3-isopropylaminopropan-2-ol; C15H23NO3;6452-71-7�Oxprenolol Hydrochloride 6452-73-9; APSOLOX; SLOW-PREN; SLOW-TRASICOR;TRASICOR; TRASIDREX*Beta-adrenoceptor antagonist
O
OCH2
OHHNHPr i
and enantiomer
Oxybuprocaine oks·ë·bü·prö·kän2-Diethylaminoethyl 4-amino-3-butoxybenzoate; C17H28N2O3; 99-43-4Oxybuprocaine Hydrochloride 5987-82-6; MINIMS BENOXINATE
Local anaesthetic
OH3CO
NEt2
H2N
O
Oxybutynin oks·ë·bü·ti·nin4-Diethylaminobut-2-ynyl 2-cyclohexyl-2-phenylglycolate; C22H31NO3;5633-20-5�Oxybutynin Hydrochloride Oxybutynin chloride (USAN); 1508-65-2 CYSTRIN;DITROPAN
Anticholinergic
NEt2
O
HOO
�Oxycinchophen3-Hydroxy-2-phenylquinoline-4-carboxylic acid; C16H11NO3; 485-89-2
N
OH
COOH
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3-129�Oxyclozanide oks·ö·klö·za·nïd
3,3¢,5,5¢,6-Pentachloro-2¢-hydroxysalicylanilide; C13H16Cl5NO3;2277-92-1; ̈ LEVAFAS* ̈ NILZAN*; ̈ RYCOVET DUOSPEC*; ̈ SYSTAMEX PLUS*; ̈ WORMAWAY*;¨ZANIL
Anthelmintic
NH
Cl
OH
Cl
Cl
O
Cl
Cl
OH
Oxycodone oks·ë·kö·dön(1) (-)-(5R,14S)-4,5-Epoxy-14-hydroxy-3-methoxy-9a-methylmorphinan-6-one;(2) 6-deoxy-7,8-dihydro-14-hydroxy-3-O-methyl-6-oxomorphine; C18H21NO4; 76-42-6Opioid analgesic
NMe
O
MeO
OH
O
Oxyfedrine oks·ë·fe·drën3-(b-Hydroxy-a-methylphenethylamino)-3¢-methoxypropiophenone; C19H23NO3;15687-41-9Vasodilator
NH
OMe
O Me H
H OH
Oxymesterone oks·ë·mes·te·rön4,17b-Dihydroxy-17a-methylandrost-4-en-3-one; C20H30O3; 145-12-0Anabolic steroid; androgen
O
OH
Me
H
H
H
Me Me
OH
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3-130Oxymetazoline oks·ë·me·tä·zö·lën
6-tert-Butyl-3-(2-imidazolin-2-ylmethyl)-2,4-xylenol; C16H24N2O;1491-59-4�Oxymetazoline Hydrochloride 2315-02-8; AFRAZINE
Alpha-adrenoceptor agonist
N
NH
Me
Bu t
OH
Me
�Oxymetholone oks·ë·me·tho·lön17b-Hydroxy-2-hydroxymethylene-17a-methyl-5a-androstan-3-one; C21H32O3; 434-07-1Anabolic steroid; androgen
O
Me
H
H
H
Me Me
OH
H
OH
Oxymorphone oks·ë·mor·fön(1) (-)-(5R,14S)-4,5-Epoxy-3,14-dihydroxy-9a-methylmorphinan-6-one; (2) 6-deoxy-7,8-dihydro-14-hydroxy-6-oxomorphine; C17H19NO4;76-41-5Opioid analgesic
NMe
O
HO
OH
O
Oxypertine oks·ë·per·tën5,6-Dimethoxy-2-methyl-3-[2-(4-phenylpiperazin-1-yl)ethyl]indole; C23H29N3O2;153-87-7Oxypertine Hydrochloride 40523-01-1; INTEGRIN
Antipsychotic
N
N
N
MeO
MeO
MeH
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3-131��Oxyphenbutazone oks·ë·fen·bü·ta·zön
4-Butyl-1-(4-hydroxyphenyl)-2-phenylpyrazolidine-3,5-dione; C19H20N2O3; 129-20-4
N
N
O
O
OH
Bun
H
and enantiomer
Oxyphencyclimine oks·ë·fen·sï·kli·mën1,4,5,6-Tetrahydro-1-methylpyrimidin-2-ylmethyl a-cyclohexylmandelate;C20H28N2O3; 125-53-1Anticholinergic
ON
HO
O
N
Me
and enantiomer
Oxyphenisatine (oxyphenisatin) oks·ë·fe·nï·sa·tën3,3-Bis(4-hydroxyphenyl)indolin-2-one; C20H15NO3; 125-13-3Oxyphenisatine Diacetate 115-33-3; VERIPAQUE
Laxative
N O
OAc
OAc
H
Oxyphenonium Bromide oks·ë·fe·nö·në·um2-(a-Cyclohexylmandeloyloxy)ethyldiethylmethylammonium bromide;C21H34BrNO3; 50-10-2Anticholinergic
OHO
O
NEt2
Me
and enantiomer
+
Br_
Oxypurinol see Oxipurinol
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3-132�Oxytetracycline oks·ë·te·tra·sï·klën
(1) (4S,4aR,5S,5aR,6S,12aS)-4-Dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,5,6,10,12,12a-hexahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide;(2) 5b-hydroxytetracycline; C22H24N2O9;79-57-2; ̈ ORNIMED; OXYDON; ̈ TETRAPLEX
�Oxytetracycline Calcium 15251-48-6; TRIMOVATE CREAM*�Oxytetracycline Dihydrate 6153-64-6; ̈ DUPHACYCLINE; ̈ ENGEMYCIN;¨OCCRYCETIN; ̈ OXYCARE; OXYMYCIN; OXYSENTIN; TERRAMYCIN INJECTION; ̈ TETRAMIN
�Oxytetracycline Hydrochloride 2058-46-0; ¨ALAMYCIN; ¨AQUATET;¨DUPHACYCLINE; ̈ EMBACYCLINE; ̈ ENGEMYCIN; ̈ FINABIOTIC*; ̈ INTRACYCLINE; ̈ MYCEN;¨OCCRYCETIN; ̈ OXYCOMPLEX*; ̈ OXYMAST; OXYMYCIN; ̈ OXYTETRIN; TERRAMYCIN CAPSULES;TERRA-CORTRIL*; ̈ TETCIN; ̈ TETRA; ̈ TETROXY
Antibiotic
OH O HO O
CONH2
OH
NMe2HH
MeHO
OH
OH
�Oxytocin oks·ë·tö·sinC43H66N12O12S2; 50-56-6; SYNTOCINON; SYNTOMETRINE*Oxytocic
Cys-Tyr-Ile-Gln-Asn-Cys-Pro-Leu-Gly-NH2
Paclitaxel pa·kli·taks·el(2S,5R,7S,10R,13S)-10,20-Bis(acetoxy)-2-benzoyloxy-1,7-dihydroxy-9-oxo-5,20-epoxytax-11-en-13-yl (3S)-3-benzoylamino-3-phenyl-D-lactate; C47H51NO14; 33069-62-4; taxol A; TAXOL
Antineoplastic
H
OHAcO O
Me
Me
OAcO
OMe
O
Me
HON
OH
OHO
O
H
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3-133Padimate pa·di·mät
A mixture of pentyl, isopentyl and 2-methylbutyl 4-dimethylaminobenzoates; 14779-78-3; COPPERTONE SUPERSHADE*; SPECTRABAN*Padimate O 2-ethylhexyl 4-dimethylaminobenzoate; C17H27NO2;21245-02-3; ESCALOL 507Sunscreen
Me2N
O CH3
O
CH3
padimate O
Palatrigine pa·la·tri·jën6-(2,3-Dichlorophenyl)-2,3-dihydro-3-imino-2-isopropyl-1,2,4-triazin-5-ylamine;C12H13Cl2N5; 98410-36-7; BW A256CAnti-arrhythmic
N
NN
Cl
Cl
Pr i
NHH2N
Palivizumab pa·li·viz·ü·mabImmunoglobulin G 1 (human-mouse monoclonal MEDI-493g1-chainantirespiratory syncytial virus protein F), disulfide with human-mouse monoclonalMEDI-493k1-chain, dimerImmunomodulator
Pamidronic Acid pa·mi·dro·nik3-Amino-1-hydroxypropylidenebis(phosphonic acid); C3H11NO7P2;40391-99-9Disodium Pamidronate 57248-88-1; AREDIA
Treatment of malignant hypercalcaemia
P
O
OH
OHP
O
OH
HO C
OH
NH2
�Pancreatin (BAN) pan·krë·a·tinA preparation of mammalian pancreas containing enzymes having protease, lipaseand amylase activity; 8049-47-6; CREON; NUTRIZYM GR; PANCREASE; PANCREX;¨ TRYPLASE
Enzyme
�Pancreozymin (BAN)A polypeptide hormone obtained from duodenal mucosa; cholecystokininDiagnostic aid
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3-134�Pancuronium Bromide pan·kûr·rö·në·um
1,1¢-(3a,17b-Diacetoxy-5a-androstan-2b,16b-ylene)bis(1-methylpiperidinium)dibromide; C35H60Br2N2O4; 15500-66-0; PAVULON
Neuromuscular blocker
NNMe
AcO
Me
H
H
H
H
Me OAc
Me+ + 2Br
_
�Panidazole2-Methyl-5-nitro-1-[2-(4-pyridyl)ethyl]imidazole; C11H12N4O2;13752-33-5
N
N
N
Me
NO2
Panthenol pan·the·nol(±)-2,4-Dihydroxy-N-(3-hydroxypropyl)-3,3-dimethylbutyramide; pantothenylalcohol; C9H19NO4; 17307-32-3; MULTIBIONTA*Pantothenic acid analogue
HON OH
Me Me
HO H
O
H
and enantiomer
Pantoprazole pan·to·pra·zôl5-Difluoromethoxybenzimidazol-2-yl 3,4-dimethoxy-2-pyridylmethyl sulfoxide;C16H15F2N3O4S; 102625-70-7; PROTIUM
Proton pump inhibitor; treatment of gastric acid-related gastrointestinal disorders
N
N SN
O
O
OMeMeO
F2HC
H
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3-135Pantothenic Acid (BAN) pan·tö·thë·nik
(R)-N-(2,4-Dihydroxy-3,3-dimethylbutyryl)-b-alanine; C9H18NO5;79-83-4; SOLVITO*Calcium Pantothenate ALLBEE*; AMERICAN NUTRITION*; BC 500*; CALCIMAX*;CANTOPAL; CONCAVIT*; DALIVIT*; FEFOL VIT*; GEVRAL*; KETOVITE*; UNICAP*Vitamin B component
HON
COOHMe Me
HO H
O
H
Panuramine pan·ûr·ra·mën(1) 1-Benzoyl-3-[1-(2-naphthylmethyl)4-piperidyl]urea; (2) N-[1-(2-naphthylmethyl)piperidin-4-ylaminocarbonyl]benzamide; C24H25N3O2; 80349-58-2Panuramine Hydrochloride 80349-03-7; Wy 26002Antidepressant
N N
O O N
H H
Papaveretum (BAN) pa·pa·ve·rë·tumA mixture of 253 parts of morphine hydrochloride, 23 parts of papaverinehydrochloride and 20 parts of codeine hydrochloride; 8002-76-4; ASPAV*Opioid analgesic
Papaverine (BAN) pa·pa·ve·rën1-(3,4-Dimethoxybenzyl)-6,7-dimethoxyisoquinoline; C20H21NO4;58-74-2�Papaverine Hydrochloride 61-25-6; BROVON*Antispasmodic
NOMe
OMe
MeO
MeO
Papaveroline pa·pa·ve·ro·lën1-(3,4-Dihydroxybenzyl)isoquinoline-6,7-diol; C16H13NO4; 574-77-6Vasodilator
NOH
OH
HO
OH
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3-136�Paracetamol pa·ra·set·a·mol
4¢-Hydroxyacetanilide; acetaminophen (USAN); C8H9NO2; 103-90-2; ALVEDON;ANADIN PARACETAMOL; ̈ BUDALE; CALPOL; CALPOL SIX PLUS; DISPROL; FANALGIC; FEBRILIX;HEDEX; INFADROPS; MANDANOL; MEDIMOL; MIRADOL; PALDESIC; PANADOL; PANALEVE;PARACETS; PARAMIN; PLACIDEX; SALZONE; TRAMIL; component in a large number ofproprietary preparationsAnalgesic
NHAc
HO
Parecoxib pa·re·koks·ibN-[4-(5-Methyl-3-phenyl-1,2-oxazol-4-yl)phenylsulfonyl]propanamide;C19H18N2O4S; 198470-84-7Parecoxib SodiumCyclo-oxygenase-2 inhibitor
NO
SNH
CH3
Me
OO O
Paramethadione pa·ra·me·tha·dï·ön(RS)-5-Ethyl-3,5-dimethyl-1,3-oxazolidine-2,4-dione; C7H11NO3; 115-67-3Anticonvulsant
NMe
O O
O
Me
Et
and enantiomer
Paramethasone pa·ra·me·tha·sön6a-Fluoro-11b,17a,21-trihydroxy-16a-methylpregna-1,4-diene-3,20-dione;C22H29FO5; 53-33-8Paramethasone Acetate 1597-82-6Corticosteroid
O
F
Me
H
H
H
Me
OAc
OHMeO
HO
Parbendazole par·ben·da·zôlMethyl 5-butylbenzimidazol-2-ylcarbamate; C13H17N3O2; 14255-87-9Anthelmintic
N
N NHCOOMe
Bun
H
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3-137Pargyline par·ji·lën
Benzylmethylprop-2-ynylamine; C11H13N; 555-57-7Pargyline Hydrochloride 306-07-0Monoamine oxidase inhibitor
N
MeCH
Parnaparin Sodium par·na·pa·rinSodium salt of depolymerised heparin obtained by hydrogen peroxide andcopper(II) acetate degradation of heparin from pork intestinal mucosa; the majorityof the components have a 2-N,6-O-disulfo-D-glucosamine structure at the reducingend of their chain; the molecular weight of these components lies between 4000and 5000 (±20%); the degree of sulfation is 2.15 (±10%) per disaccharide unit;OP 21-23Anticoagulant
Paromomycin pa·rö·mö·mï·sinAntimicrobial aminoglycosides produced by Streptomyces rimosus var. paromomycinus;7542-37-2Antibiotic
Paroxetine pa·roks·e·tën5-[(3S,4R)-4-p-Fluorophenyl-3-piperidylmethoxy]-1,3-benzodioxole; C19H20FNO3;61869-08-7Paroxetine Hydrochloride SEROXAT
Antidepressant
O
O O NH
F
Parvaquone par·va·kwön2-Cyclohexyl-3-hydroxy-1,4-naphthoquinone; C16H16O3; 4042-30-2Theilericide (veterinary)
O
O
OH
�Pecazine10-(1-Methyl-3-piperidylmethyl)phenothiazine; C19H22N2S; 60-89-9
N
SN
Me
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3-138�Pecilocin
An antibiotic produced by Paecilomyces varioti Bainier var. antibioticus;1-[(2E,4E,6Z,8R)-8-hydroxy-6-methyldodeca-2,4,6-trienoyl]-2-pyrrolidone;C17H25NO3; 19504-77-9Antibiotic
NCH3
O
O
Me
H OH
H
�Pefloxacin pe·floks·a·sin1-Ethyl-6-fluoro-1,4-dihydro-7-(4-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid; C17H20FN3O3; 70458-92-3Antibacterial
NN
N
F
Me
O
COOH
Et
Peginterferon Alfa-2bPegylated, recombinant interferon alfa-2b
Treatment of chronic hepatitus C
peginterferon alfa-2b has the following amino acid sequence:
(M)CDLPQTHSLG SRRTLMLLAQ MRRISLFSCL
KDRHDFGFPQ EEFGNQFQKA ETIPVLHEMI
QQIFNLFSTK DSSAAWDETL LDKFYTELYQ
QLNDLEACVI QGVGVTETPL MKEDSILAVR
KYFQRITLYL KEKKYSPCAW EVVRAEIMRS
FSLSTNLQES LRSKE
*
*
*
*potential pegylation sites
*
*
*
*
*
*
* **
Pemoline pe·mo·lën(RS)-2-Amino-5-phenyl-4-oxazolidone; C9H8N2O2; 2152-34-3; VOLITAL
Central nervous system stimulant
N
O NH2
O
and enantiomer
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3-139Pempidine pem·pi·dën
1,2,2,6,6-Pentamethylpiperidine; C10H21N; 79-55-0Ganglion blocker
NMe
Me
Me
Me
Me
�PenamecillinAcetoxymethyl (6R)-6-(2-phenylacetamido)penicillanate; C19H22N2O6S;983-85-7
HN
NOO
S
H
Me
Me
H H
O O CH3
O O
�Penbutolol pen·bü·to·lol(S)-1-tert-Butylamino-3-(2-cyclopentylphenoxy)propan-2-ol; C18H29NO2; 38363-40-5Beta-adrenoceptor antagonist
O NHBu tOHH
Penciclovir pen·sï·klö·veer9-[4-Hydroxy-3-(hydroxymethyl)butyl]guanine; C10H15N5O3; 39809-25-1; VECTAVIR
Antiviral
N
N
N
O
HN
OH
OHH2N
Pendecamaine pen·de·ka·mänDimethyl(3-palmitamidopropyl)ammonioacetate; C23H46N2O3; 32954-43-1Surface active agent
C15H31 N N COO_
O
Me MeH
+
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3-140Pendetide pen·de·tïd
Glycyl-L-tyrosyl-N 6-[N-(2-{2-[bis(carboxymethyl)amino]ethyl(carboxymethyl)-amino}ethyl)-N-(carboxymethyl)glycyl]-L-lysine; C3lH47N7O14Diagnostic aid (see indium[111In] satumomab pendetide under satumomab)
HOOC
NHOOC
HOOC N
HN
O
COOH
NHN
COOHH
Gly–Tyr
Penethamate (BAN) pen·e·tha·mät2-Diethylaminoethyl (6R)-6-(2-phenylacetamido)penicillanate; C22H31N3O4SPenethamate Hydriodide 808-71-9; ̈ LEOCILLIN; ̈ LEO RED DC*; ̈ LEO YELLOW MC*Treatment of respiratory tract infections
HN
NOO
S
Me
Me
H H
ONEt2
O
H
Penfluridol pen·flûr·ri·dol4-(4-Chloro-3-trifluoromethylphenyl)-1-[3-(p,p¢-difluorobenzhydryl)-propyl]piperidin-4-ol; C28H27ClF5NO; 26864-56-2Antipsychotic
N
F
F
HO
CF3
Cl
�Penicillamine pe·ni·si·la·mën3,3-Dimethyl-D-cysteine; D-penicillamine; C5H11NO2S; 52-67-5; DISTAMINE;PENDRAMINE
Chelating agent; treatment of rheumatoid arthritis
HSCOOH
H NH2
MeMe
�PenicillinaseAn enzyme from cultures of Bacillus cereus or B. subtilis which hydrolysesbenzylpenicillin to penicilloic acid; 9001-74-5
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3-141�Pentacosactride (BAN)
[1-D-Serine,4-norleucine,25-valine]corticotrophin-(1-25)-pentacosapeptide amide;norleusactide (pINN; USAN); C142H222N42O31; 17692-62-5
D-Ser-Tyr-Ser-Nle-Glu-His-Phe-Arg-Trp-
Gly-Lys-Pro-Val-Gly-Lys-Lys-Arg-Arg-
Pro-Val-Lys-Val-Tyr-Pro-Val-NH2
�Pentacynium Metilsulfate (BAN)4-[2-(5-Cyano-5,5-diphenylpentyldimethylammonio)ethyl]-4-methylmorpholiniumdi(methylsulfate); C30H48N3O13S3; 77-12-3
NCN MeMe
N
OMe CH3SO3
_2
+ +
�Pentaerythrityl Tetranitrate (pentaerythritol tetranitrate) pen·ta·e·ri·thri·tïl2,2-Bis(hydroxymethyl)propane-1,3-diol tetranitrate; C5H8N4O12;78-11-5; MYCARDOL
Vasodilator
ONO2
ONO2
O2NO
O2NO
Pentafluranol pen·ta·flûr·ra·nol(1R,2S)-3,3¢-Difluoro-4,4¢-[1-methyl-2,2,2-trifluoroethyl)-ethylene]diphenol;C17H15F5O2; 54043-46-8; BX 430Treatment of benign hypertrophy of the prostate
Me H
CF3
H
HO
OH
F
F
��Pentagastrintert-Butyloxycarbonyl-[b-Ala13]gastrin-(13-17)-pentapeptide amide; C37H49N7O9S;5534-95-2
Boc-β-Ala-Trp-Met-Asp-Phe-NH2
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3-142�Pentalamide
(1) 2-Pentyloxybenzamide; (2) O-pentylsalicylamide; C12H17NO2;5579-06-6
OCH3
CONH2
Pentamethonium Bromide pen·ta·me·thö·në·umN,N¢-Pentamethylenebis(trimethylammonium) dibromide; C11H28Br2N2; 541-20-8Ganglion blocker
Me3N NMe3
+ +2Br
_
�Pentamethonium IodideN,N¢-Pentamethylenebis(trimethylammonium) di-iodide; C11H28I2N2;5282-80-4
Me3N NMe3
+ +2 I
_
Pentamidine pen·ta·mi·dën4,4¢-(Pentamethylenedioxy)dibenzamidine; C19H24N4O2; 100-33-4�Pentamidine Isetionate 140-64-7; PENTACARINATE
Antiprotozoan
H2N
O O
NH2
NH NH
Pentapiperide pen·ta·pi·per·rïd1-Methylpiperidin-4-yl 3-methyl-2-phenylvalerate; C18H27NO2;7009-54-3Anticholinergic
O
NMeO
CH3Me
H H*
*
mixture of stereoisomers
Pentaquine pen·ta·kwën5-Isopropylaminopentyl(6-methoxy-8-quinolyl)amine; C18H27N3O;86-78-2Antimalarial
N
HN NHPr i
MeO
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3-143Pentastarch pen·ta·starch
A starch in which more than 90% of the amylopectin has been etherified to theextent that on average 4 or 5 of the-OH groups present in every10 D-glucopyranose units of the starch polymer have been converted to -OCH2CH2OH groups; 9005-27-0; PENTASPAN
Plasma volume expander
�Pentazocine pen·tä·zö·sën(2R*,6R*,11R*)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-(3-methylbut-2-enyl)-2,6-methano-3-benzazocin-8-ol; C19H27NO; 359-83-1�Pentazocine Hydrochloride 64024-15-3; FORTAGESIC*; FORTRAL
Pentazocine Lactate 17146-95-1; FORTRAL INJECTION
Opioid analgesic
NMe
HO
CMe2
H
Me H
and enantiomer
Pentetic Acid pen·te·tik[Carboxymethyliminobis(ethylenenitrilo)]tetra-acetic acid; C14H23N3O10; 67-43-6Radiodiagnostic aid
HOOC NN
N
COOH
COOH
HOOC
COOH
Pentetrazol pen·te·tra·zol6,7,8,9-Tetrahydro-5H-tetrazoloazepine; leptazol; C6H10N4; 54-95-5Central nervous system stimulant
N N
NN
Pentetreotide pen·te·trë·ö·tïdN-{2-[{2-[Bis(carboxymethyl)amino]ethyl}(carboxymethyl)amino]ethyl}-N-(carboxymethyl)glycyl-D-phenylalanyl-L-cysteinyl-L-phenylalanyl-D-tryptophyl-L-lysyl-L-threonyl-L-cysteinyl-(2R,3R)-threoninol cyclic disulfide (S3¾ S8);C63H87N13Ol9S2; 138661-02-6; SDZ 215-811; OCTREOSCAN
Diagnostic aid; cytotoxic
N
N COOH
COOHN
COOH COOH
O
D-Phe-Cys-Phe-D-Trp-Lys-Thr-Cys
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3-144Penthienate (BAN) pen·thï·e·nät
2-Diethylaminoethyl 2-cyclopentyl-2-(2-thienyl)glycolate; C17H27NO3S; 22064-27-3Penthienate Bromide penthienate methobromide; 60-44-6Anticholinergic
S
HO
O
NMe2O
Penthrichloral pen·thri·klor·ral5,5-Bis(hydroxymethyl)-2-trichloromethyl-1,3-dioxane; C7H11N3O4;5684-90-2Hypnotic
O
O
OH
OH
Cl3C
Pentifylline pen·ti·fi·lën1-Hexyl-3,7-dimethylxanthine; C13H20N4O2; 1028-33-7Vasodilator
N
N
N
N
O
O
Me
H3C
Me
�Pentobarbital (pentobarbitone) pen·tö·bar·bi·tal5-Ethyl-5-(1-methylbutyl)barbituric acid; C11H18N2O3; 76-74-4�Pentobarbital Sodium 57-33-0; ̈ DOLETHAL ̈ EXPIRAL; ̈ EXITAL; ̈ EUTHANASIA;¨EUTHATAL; ̈ EUTHESATE; ̈ LETHOBARB; ̈ PENTOJECT; ̈ SAGATAL
Hypnotic
NH
N OO
O
H3C
EtMe H
H
and enantiomer
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3-145Pentolonium Tartrate (pentolinium tartrate) pen·to·lö·në·um
N,N¢-Pentamethylenebis(1-methylpyrrolidinium) di(hydrogen tartrate);C23H42N2O12; 52-62-0Ganglion blocker
N N
Me Me
+ +
HOOCCOO
_OHH
H OH 2
Pentosalen (BAN) pen·tö·sa·len9-(3-Methylbut-2-enyloxy)furo[3,2-g]chromen-7-one; ammidin; C16H14O4; 482-44-0Aid to dermal pigmentation
O O
O Me
Me
O
Pentosan Polysulfate Sodium pen·tö·san po·lë·sul·fätA mixture of linear polymers of b-1® 4-linked xylose, usually sulfated at the 2-and3-positions and occasionally (approximately 1 in every 4 residues) substituted at the2-position with 4-O-methyl-a-D-glucuronic acid 2,3-O-sulfate; the averagemolecular weight lies between 4000 and 6000 with a total molecular weight rangeof l000 to 40,000; 37319-17-8; SP54;¨CARTROPHEN VET
Anticoagulant
Pentostatin pen·tö·sta·tin1,2-Dideoxy-1-[(R)-3,6,7,8-tetrahydro-8-hydroxyimidazo[4,5-d][1,3]diazepin-3-yl]-D-erythro-pentofuranose; covidarabine; 2¢-deoxycoformycin; deoxycoformycin;C11H16N4O4; 53910-25-1; NIPENT
Adenosine deaminase (ADA) inhibitor
O
OH
HO
H OH
HN
N
N
N
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3-146Pentoxifylline / Oxpentifylline pen·toks·i·fi·lën/oks·pen·ti·fi·lën
3,7-Dimethyl-1-(5-oxohexyl)xanthine; C13H18N4O3; 6493-05-6; TRENTAL
Vasodilator
N
N
N
N
O
O
Me
H3C
MeO
�Peratizole1-[4-(2,4-Dimethyl-1,3-thiazol-5-yl)butyl]-4-(4-methyl-1,3-thiazol-2-yl)piperazine;C17H26N4S2; 29992-13-4
SN
N
N
Me
MeS
N
Me
Perfluamine per·floo·a·mënTris(heptafluoropropyl)amine; C9F21N; 338-83-0; FLUOSOL*Oxygen transporter during percutaneous transluminal coronary angioplasty
N
CF2CF2CF3
CF2CF2CF3F3CF2CF2C
Perflunafene per·floo·na·fënPerfluorodecahydronaphthalene; C10F18; 306-94-5; FLUOSOL*Oxygen transporter during percutaneous transluminal coronary angioplasty
FFF
FF FF F
FFFF
F FF
FFF
Pergolide per·gö·lïdMethyl (8R,10R)-6-propylergolin-8-ylmethyl sulfide; C19H26N2S; 66104-22-1Pergolide Mesilate 66104-23-2; CELANCE
Dopamine receptor agonist
HN
N
H
SMe
HPrn
H
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3-147�Perhexiline
(RS)-2-(2,2-Dicyclohexylethyl)piperidine; C19H35N; 6621-47-2Vasodilator
HN
H
and enantiomer
Pericyazine pe·ri·sï·a·zën1-[3-(2-Cyanophenothiazin-10-yl)propyl]piperidin-4-ol; periciazine (pINN);C21H23N3OS;2622-26-6; NEULACTIL
Antipsychotic
N
S
N
OH
CN
Perindopril per·rin·dö·pril(2S,3aS,7aS)-1-{N-[(S)-1-Ethoxycarbonylbutyl]-L-alanyl}perhydroindole-2-carboxylic acid; C19H32N2O5; 82834-16-0; COVERSYL
Angiotensin-converting enzyme inhibitor
H
MeHO
NH3C
H
H
H
COOH
H
COOEt
Perindoprilat per·rin·dö·pri·lat(2S,3aS,7aS)-1-{N-[(S)-1-Carboxybutyl]-L-alanyl}perhydroindole-2-carboxylicacid; C17H28N2O5; 95153-31-4; S-9780Angiotensin-converting enzyme inhibitor
H
MeHO
NH3C
H
H
H
COOH
H
COOH
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3-148Perlapine per·la·pën
6-(4-Methylpiperazin-1-yl)-11H-dibenz[b,e]azepine; C19H21N3; 1977-11-3; HF-2333; AW-142333Hypnotic
NN
MeN
Permethrin per·mëth·rin3-Phenoxybenzyl *(1RS,3RS)-(1RS,3SR)-3-(2,2-dichlorovinyl)-2,2-dimethylcyclopropanecarboxylate; C21H20Cl2O3; 52645-53-1; ̈ BEATITCH; ̈ CANOVEL;¨CATOVEL; ̈ COMPANION; ̈ DEFENCARE; ̈ DEFENCAT; ̈ DEFENDOG; ̈ EXSPOT; ̈ FLYPOR;¨LINCOLN; LYCLEAR; ̈ RIDECT; ̈ RUBY; ̈ SECTINE; ̈ SWIFT; ̈ SWITCH
Insecticide*alternative designation: (1RS)-cis-trans-3-(2,2-dichloro...
Me
Me
H
Cl
Cl
H O
O
OH
1R,3S-isomer
�Perphenazine per·fen·a·zën2-{4-[3-(2-Chlorophenothiazin-10-yl)propyl]piperazin-1-yl}ethanol;C21H26ClN3OS; 58-39-9; FENTAZIN; TRIPTAFEN*Antiemetic
N
S
N
N
Cl
OH
Pethidine pe·thi·dënEthyl 1-methyl-4-phenylpiperidine-4-carboxylate; C15H21NO2; 57-42-1�Pethidine Hydrochloride meperidine hydrochloride (USAN); 50-13-5;PAMERGAN*;Opioid analgesic
MeN
O CH3
O
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3-149Phanquinone (phanquone) fan·kwi·nön
4,7-Phenanthroline-5,6-dione; C12H6N2O2;84-12-8Antiprotozoan
N
N
O
O
�Phenacemide(Phenylacetyl)urea; C9H10N2O2; 63-98-9
N NH2
O O
H
�Phenactropinium Chloride(1R,3r,5S,8s)-[(RS)-3-Mandeloyloxy-8-phenacyl]tropanium chloride;C24H28ClNO4; 3784-89-2
and enantiomer
NMe
O
O
O
H OH
+
Cl_
Phenadoxone fen·a·doks·ön6-Morpholino-4,4-diphenylheptan-3-one; C23H29NO2; 4467-84-5Opioid analgesic; antitussive
O
MeH
NO
CH3
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3-150Phenaglycodol fen·a·glï·kö·dol
2-(4-Chlorophenyl)-3-methylbutane-2,3-diol; C11H15ClO2; 79-93-6Anxiolytic; sedative
*CH3
Me OH
Me OHCl
*
mixture of stereoisomers
Phenampromide fen·am·prö·mïdN-(1-Methyl-2-piperidinoethyl)propionanilide; C17H26N2O; 129-83-9Opioid analgesic
NN
CH3O
H Me
and enantiomer
Phenazocine fen·ä·zö·sën(2R*,6R*,11R*)-1,2,3,4,5,6-Hexahydro-6,11-dimethyl-3-phenethyl-2,6-methano-3-benzazocin-8-ol; C22H27NO; 127-35-5Phenazocine Hydrobromide 1239-04-9; NARPHEN
Opioid analgesic
NMe
HO
Me H
and enantiomer
��Phenazone2,3-Dimethyl-1-phenyl-3-pyrazolin-5-one; antipyrine (USAN); C11H12N2O; 60-80-0
NN
O
Me
Me
�Phenazopyridine fen·ä·zö·pi·ri·dën3-Phenylazopyridine-2,6-diyldiamine; C11H11N5; 94-78-0Analgesic
NNN
NH2
H2N
Phenbenicillin see Fenbenicillin
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3-151Phenbutrazate see Fenbutrazate
�Phencyclidine1-(1-Phenylcyclohexyl)piperidine; C17H25N; 77-10-1
N
Phendimetrazine fen·dï·me·tra·zën(2S-trans)-3,4-Dimethyl-2-phenylmorpholine; C12H17NO; 634-03-7Appetite suppressant
NMe
OH
MeH
Phenelzine fen·el·zënPhenethylhydrazine; C8H12N2; 51-71-8�Phenelzine Sulphate 156-51-4; NARDIL
Antidepressant
NNH2
H
Phenethicillin see Pheneticillin
Phenethyl Alcohol (BAN)2-Phenylethanol; C8H10O; 60-12-8; CEANEL*Anti-infective
OH
�Pheneticillin (phenethicillin) fen·eth·i·si·lin(6R)-6-(2-Phenoxypropionamido)penicillanic acid; C17H20N2O5S;147-55-7Antibiotic
*HN
NOO
S
H COOH
Me
Me
H H
O
Me H
and enantiomer at C*
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3-152Pheneturide fen·e·tûr·rïd
(2-Phenylbutyryl)urea; ethylphenacemide (pINN); C11H14N2O2; 90-49-3Anticonvulsant
N NH2
H Et
O O
H
�Phenformin1-Phenethylbiguanide; C10H15N5; 114-86-3
N N
NH
NH2
NH
H H
�Phenglutarimide fen·gloo·ta·ri·mïd2-(2-Diethylaminoethyl)-2-phenylglutarimide; C17H24N2O2; 1156-05-4Anticholinergic
HNNEt2
O
O
and enantiomer
Phenindamine fen·in·da·mën(RS)-2,3,4,9-Tetrahydro-2-methyl-9-phenyl-1H-indeno[2,1-c]pyridine; C19H19N;82-88-2�Phenindamine Tartrate 569-59-5; THEPHORIN
Histamine H1-receptor antagonist
NMe
H
and enantiomer
�Phenindione fen·in·dï·ön2-Phenylindan-1,3-dione; phenylindanedione; C15H10O2; 83-12-5; DINDEVAN
Anticoagulant
O
O
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3-153Pheniprazine fen·i·pra·zën
a-Methylphenethylhydrazine; C9H14N2; 55-52-7Monoamine oxidase inhibitor
N
H Me
H
NH2
ans enantiomer
Pheniramine fen·îr·ra·mënDimethyl[3-phenyl-3-(2-pyridyl)propyl]amine; C16H20N2; 86-21-5�Pheniramine Maleate 132-20-7; DANERAL SA; TRIOMINIC*Histamine H1-receptor antagonist
N
NMe2
H
and enantiomer
�Phenmetrazine(±)-trans-3-Methyl-2-phenylmorpholine; C11H15NO; 134-49-6
NH
O
Me
and enantiomer
�Phenobarbital (phenobarbitone) fë·nö·bar·bi·tal5-Ethyl-5-phenylbarbituric acid; C12H12N2O3; 50-06-6; SEOMINAL*�Phenobarbital Sodium 57-30-7; PHENOBARBITAL SPANSULE
Anticonvulsant
NH
N OO
O
Et
H
Phenobutiodil fë·nö·bü·tï·ö·dil2-(2,4,6-Tri-iodophenoxy)butyric acid; C10H9I3O3; 554-24-5; BILIODYL
Contrast medium
and enantiomer
OCH3
H COOH
I
II
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3-154�Phenolphthalein fë·nol·fthä·lën
3,3-Bis(4-hydroxyphenyl)phthalide; C20H14O4; 77-09-8; AGAROL*; ALOPHEN*; EX-LAX;KEST*Laxative
O
O
OH
OH
�Phenolsulphonphthalein (BAN) fë·nol·sul·fon·fthä·lën4,4¢-(3H-2,1-Benzoxathiol-3-ylidene)bisphenol S,S-dioxide; C19H14O5S;143-74-8Diagnostic aid
O
OH
OH
SO O
Phenomorphan fë·nö·mor·fan(-)-9a-Phenethylmorphinan-3-ol; C24H29NO; 468-07-5Opioid analgesic
N
HO
H
�Phenoperidine fë·nö·pe·ri·dënEthyl 1-(3-hydroxy-3-phenylpropyl)-4-phenylpiperidine-4-carboxylate; C23H29NO3;562-26-5Phenoperidine Hydrochloride 3627-49-4; OPERIDINE
Opioid analgesic
NCOOEt
H OH
and enantiomer
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3-155Phenothrin fë·nö·thrin
3-Phenoxybenzyl (1RS,3RS; 1RS,3SR)-2,2-dimethyl-3-(2-methylprop-1-enyl)cyclopropanecarboxylate; C23H26O3; 26002-80-2; FULL MARKS
Insecticide
Me
Me
H
Me
Me
H O
O
OH
1R,3S-isomer
Phenoxybenzamine fen·oks·ë·ben·za·mënBenzyl(2-chloroethyl)(1-methyl-2-phenoxyethyl)amine; C18H22ClNO;59-96-1�Phenoxybenzamine Hydrochloride 63-92-3; DIBENYLINE
Alpha-adrenoceptor antagonist
ON
Cl
H Me
and enantiomer
�Phenoxymethylpenicillin fen·oks·ë·më·thïl·pen·i·si·lin(6R)-6-(2-Phenoxyacetamido)penicillanic acid; penicillin V (USAN); C16H18N2O5S;87-08-1�Phenoxymethylpenicillin Potassium 132-98-9 ¨POTENCIL
Antibiotic
HN
NOO
S
H COOH
Me
Me
H H
O
Phenoxypropazine see Fenoxypropazine
Phenprobamate fen·prö·ba·mät3-Phenylpropyl carbamate; C10H13NO2; 673-31-4Skeletal muscle relaxant
O
O
NH2
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3-156Phenprocoumon fen·prö·kü·mon
4-Hydroxy-3-(1-phenylpropyl)coumarin; C18H16O3; 435-97-2Anticoagulant
O
OH H Et
O
and enantiomer
Phensuximide fen·suks·i·mïd(RS)-N-Methyl-2-phenylsuccinimide; C11H11NO2; 486-34-0Anticonvulsant
NMeO
OH
and enantiomer
Phentermine fen·ter·mëna,a-Dimethylphenethylamine; C10H15N; 122-09-8; DUROMINE (an ion-exchange resincomplex); IONAMIN
Central nervous system stimulant
NH2
Me Me
Phentolamine fen·to·la·mën3-[N-(2-Imidazolin-2-ylmethyl)-p-toluidino]phenol; C17H19N3O; 50-60-2�Phentolamine Mesilate 65-28-1; ROGITINE
Alpha-adrenoceptor antagonist
N
N
N
Me
OH
H
Phenyl Aminosalicylate see Fenamisal
�Phenylbutazone fë·nïl·bü·ta·zön4-Butyl-1,2-diphenylpyrazolidine-3,5-dione; C19H20N2O2; 50-33-9; ̈ COMPANAZONE;¨EQUI-PALAZONE; ̈ PHENOGEL; ̈ PHENYCARE; ̈ PHENYZENE; ̈ PRO-DYNAM; ̈ TOMANOL*Analgesic; anti-inflammatory
N
N
O
O
Bun
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3-157�Phenylephrine fë·nïl·e·frën
(S)-1-(3-Hydroxyphenyl)-2-methylaminoethanol; C9H13NO2; 59-42-7�Phenylephrine Hydrochloride 61-76-7; FENOX; MINIMS PHENYLEPHRINE; present inmany other proprietary preparationsPhenylephrine Tartrate DUO-AUTOHALER*Alpha-adrenoceptor agonist
HO NHMeH OH
Phenylpropanolamine fë·nïl·prö·pa·no·la·mën(1RS,2SR)-2-Amino-1-phenylpropan-1-ol; C9H13NO; 14838-15-4�Phenylpropanolamine Hydrochloride 154-41-6; ¨PROPALIN; component ofmany other proprietary preparationsSympathomimetic
CH3
H OH
H NH2
and enantiomer
Phenyltoloxamine fë·nïl·tol·oks·a·mën2-(2-Benzylphenoxyl)ethyldimethylamine; C17H21NO; 92-12-6Phenyltoloxamine Citrate 1176-08-5Histamine H1-receptor antagonist
O
NMe2
Phenyramidol see Fenyramidol
�Phenytoin fen·ë·tö·in5,5-Diphenylimidazolidine-2,4-dione; C15H12N2O2; 57-41-0; EPANUTIN SUSPENSION;EPANUTIN INFATABS
�Phenytoin Sodium 630-93-3; EPANUTIN CAPSULES
Anticonvulsant
NH
HN O
O
Ph
Ph
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3-158�Pholcodine fol·kö·dën
(1) (-)-(5R,6S)-4,5-Epoxy-9a-methyl-3-(2-morpholinoethoxy)morphin-7-en-6-ol;(2) 3-O-(2-morpholinoethyl)morphine; C23H30N2O4;509-67-1; PAVACOL-D; TIXYLIX DAYTIME; pesent in many other proprietary preparationsAntitussive
NMe
O
O
H
HO
N
O
Pholedrine fol·e·drën4-(2-Methylaminopropyl)phenol; C10H15NO; 370-14-9Sympathomimetic
CH3
HOH NHMe
and enantiomer
Phosmet (BAN) fos·metO,O-Dimethyl S-phthalimidomethyl phosphorodithioate; C11H12NO4PS2;732-11-6; ̈ DERMOL PLUS; ̈ NUPOR; ̈ ORBISECT; ̈ PORECT; ̈ VET-CHEM
Insecticide
NS
OMe
S
P
O
O
OMe
Phoxim foks·imO,O-Diethyl a-cyanobenzylideneamino-oxyphosphorothioate; C12H15N2O3PS;14816-18-3; Bayer 9053Insecticide; anthelmintic
P
S
OEt
O OEtNNC
Phthalylsulfacetamide (BAN) ftha·lïl·sul·fa·se·ta·mïd4¢-(Acetylsulfamoyl)phthalanilic acid; C16H14N2O6S; 131-69-1; ̈ ENTEROLYTE*Antibacterial
H
S
COOH
N
O
O O
NHAc
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3-159�Phthalylsulfathiazole (phthalylsulphathiazole) ftha·lïl·sul·fa·thï·a·zôl
4¢-(1,3-Thiazol-2-ylsulfamoyl)phthalanilic acid; C17H13N3O5S2;85-73-4; ̈ NEO-SULPHENTRIN*; ̈ TRIPACIN*; ̈ VETORYL*Antibacterial
N
N
SS
COOH
N
O
O O
H
H
Physostigmine (BAN) fï·sö·stig·mën(3aS,8aR)-1,2,3,3a,8,8a-Hexahydro-1,3a,8-trimethylpyrrolo[2,3,b]indol-5-ylmethylcarbamate; eserine; C15H21N3O2; 57-47-6�Physostigmine Salicylate 57-64-7�Physostigmine Sulphate 64-47-1Anticholinesterase
N
NMeO
OMeHN
Me
Me
H
�Phytomenadione fï·tö·men·a·dï·önA mixyure of 2-methyl-3-[(2E)-7R,11R)-3,7,11,15-tetramethylhexadeca-2-enyl]naphthalene-1,4-dione and '2Z'-isomer; vitamin K1; phytonadione (USAN);C31H46O2; 84-80-0; KONAKION
Vitamin K analogue
H
O
O
Me
Me
HMeH Me
Me
Me
E-component
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3-160Piboserod pï·bö·se·rod
N-[(1-Butyl-4-piperidyl)methyl]-3,4-dihydro-2H-[1,3]oxazino[3,2-a]indole-10-carboxamide; C22H31N3O2; 152811-62-6; SB-207266-APiboserod Hydrochloride 178273-87-55HT4-receptor antagonist; treament of irritable bowel syndrome
N
O
N
O
NBunH
Picloxydine pi·kloks·ë·dën1,1¢-[Piperazine-1,4-diylbis(imidocarbonyl)]bis(3-p-chlorophenylguanidine);C20H24Cl2N10; 5636-92-0Antiseptic
N N N
N N N
Cl
Cl
NH NH
NH NH
H H H H
�Picotamide pi·kot·a·mïdN,N¢-Bis(3-pyridylmethyl)-4-methoxyisophthalamide; C21H20N4O3; 80530-87-2
Anticoagulant; fibrinolytic
N
NO
O
N
N
OMe
H
H
Picumast pi·kü·mast7-[3-(4-p-Chlorobenzylpiperazin-1-yl)propoxy]-3,4-dimethylcoumarin;C25H29ClN2O3; 39577-19-0Picumast Hydrochloride 39577-20-3 (2HCl); BM 15.100Antiallergic; antiasthmatic
N
N
Me
Me
O OO
Cl
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3-161Picumeterol pi·kü·me·te·rol
(R)-1-(4-Amino-3,5-dichlorophenyl)-2-{6-[2-(2-pyridyl)ethoxy]hexylamino}-ethanol; C21H29Cl2N3O2; GR 114297XBeta2-adrenoceptor agonist; bronchodilator
N
ClCl
NH2
HOH
ONH
�Pifenate(RS)-Ethyl 2,2-diphenyl-3-(2-piperidyl)propionate; C22H27NO2; 15686-87-0
HN
COOEt
H
and enantiomer
Pilocarpine (BAN) pï·lö·kar·pën(1) (2S,3R)-a-Ethyl-b-(1-methyl-1H-imidazol-5-ylmethyl)-g-butyrolactone; (2)(3S,4R)-3-ethyldihydro-4-[(1-methyl-1H-imidazol-5-yl)methyl]furan-2(3H)-one;C11H16N2O2; 92-13-7; OCUSERT PILO
�Pilocarpine Hydrochloride 54-71-7; ISOPTO CARPINE; OCUSERT PILO; PILOGEL; SNO
PILO; SALAGEN
�Pilocarpine Nitrate 148-72-1; MINIMS PILOCARPINE
Cholinergic
N
N O
Me
O
EtHH
�PiminodineEthyl 4-phenyl-1-(3-anilinopropyl)piperidine-4-carboxylate; C23H30N2O2; 13495-09-5
N
COOEt
NH
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3-162Pimonidazole pi·mo·nï·da·zôl
1-(2-Nitroimidazol-1-yl)-3-piperidinopropan-2-ol; C11H18N4O3;70132-50-2; Ro 03-8799Pimonidazole Hydrochloride 70132-51-3; Ro 03-8799-001Radiosensitiser
N
N NOHH
NO2
and enantiomer
Pimozide pi·mö·zïd1-{1-[3-(4,4¢-Difluorobenzhydryl)propyl]-4-piperidyl}benzimidazolin-2-one;C28H29F2N3O; 2062-78-4; ORAP
Antipsychotic
N
NH
N
F
F
O
�Pindolol pin·do·lol1-(Indol-4-yloxy)-3-isopropylaminopropan-2-ol; C14H20N2O2; 13523-86-9;VISKALDIX*; VISKEN
Beta-adrenoceptor antagonist
N
O NHPr iH OH
H
and enantiomer
Pioglitazone pï·ö·gli·ta·zön(RS)-5-{4-[2-(5-Ethyl-2-pyridyl)ethoxy]benzyl}-1,3-thiazolidin-2,4-dione;C19H20N2O3S; 111025-46-8
Oral hypoglycaemic
NHSN O
O
OH
Et
and enantiomer
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3-163�Pipamazine
1-[3-(2-Chlorophenothiazin-10-yl)propyl]piperidine-4-carboxamide;C21H24ClN3OS; 84-04-8
N
S
N
CONH2
Cl
Pipamperone pi·pam·pe·rön1-[3-(4-Fluorobenzoyl)propyl]-4-piperidinopiperidine-4-carboxamide;C21H30FN3O2; 1893-33-0Antipsychotic
N
F
ON
CONH2
Pipazetate (pipazethate) pi·pa·ze·tät2-(2-Piperidinoethoxy)ethyl pyrido[3,2-b][1,4]benzothiazine-10-carboxylate;C21H25N3O3S; 2167-85-3Antitussive
N
SN
OO
N
O
Pipecuronium Bromide pi·pe·kûr·rö·në·um1,1,1¢,1¢-Tetramethyl-4,4¢-(3a,17b-diacetoxy-5a-androstan-2b,16b-diyl)dipiperazinium dibromide; C35H62Br2N4O4; 68399-57-5 (dihydrate)Muscle relaxant
N
Me2NN NMe2
AcO
Me
H
H
H
H
Me OAc
2Br_
++
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3-164�Pipenzolate Bromide pi·pen·zo·lät
3-Benziloyloxy-1-ethyl-1-methylpiperidinium bromide; C22H28BrNO3; 125-51-9Anticholinergic
O
O
HO
NEt
Me
+Br
_
�Piperacillin pi·pe·ra·si·lin(6R)-6-[(R)-2-(4-Ethyl-2,3-dioxopiperazine-1-carboxamido)-2-phenyl-acetamido]penicillanic acid; C23H27N5O7S; 59703-84-3�Piperacillin Sodium PIPRIL; TAZOCIN*Antibiotic
NH
NOO
S
H COOH
Me
Me
H HNH
N
N
O
Et
O
O
H
�Piperazine Calcium EdetateCalcium piperazine-1,4-diylium ethylenediaminetetra-acetate; C14H24CaN4O8;12002-30-1
OO
COOHNCa
NHOOC
OO N
H
HN
•
Piperidolate pi·pe·ri·dö·lät(RS)-1-Ethyl-3-piperidyl diphenylacetate; C21H25NO2; 82-98-4Piperidolate Hydrochloride 129-77-1Anticholinergic
O
O
NEt
H
and enantiomer
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3-165Piperocaine pi·pe·rö·kän
(RS)-3-(2-Methylpiperidino)propyl benzoate; C16H23NO2; 136-82-3Local anaesthetic
O N
O MeH
and enantiomer
�Piperonyl Butoxide (BAN) pi·pe·ro·nïl bü·toks·ïd5-[2-(2-Butoxyethoxy)ethoxymethyl]-6-propyl-1,3-benzodioxole; C19H30O5; 51-03-6Acaricide
O
O
OO
OBu t
Prn
�Piperoxan(RS)-2-Piperidinomethyl-1,4-benzodioxane; C14H19NO2; 59-39-2
O
O
N
H
and enantiomer
Pipotiazine (pipothiazine) pi·pö·tï·a·zën2-{4-[3-(2-Dimethylsulfamoylphenothiazin-10-yl)propyl]piperazin-1-yl}ethanol;C24H33N3O3S2; 39860-99-6Pipotiazine Palmitate (ester); 37517-26-3; PIPORTIL
Antipsychotic
N
S
N
OH
SO2NMe2
�Pipoxolan pi·poks·o·lan(RS)-5,5-Diphenyl-2-(2-piperidinoethyl)-1,3-dioxolan-4-one; C22H25NO3;23744-24-3Antispasmodic
O
O
O
NH
and enantiomer
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3-166Pipradrol pi·pra·drol
(RS)-a-2-Piperidylbenzhydrol; C18H21NO; 467-60-7Central nervous system stimulant
N
OH
H H
and enantiomer
�Piprinhydrinate4-Benzhydryloxy-1-methylpiperidinium 8-chloro-1,2,3,6-tetrahydro-1,3-dimethyl-2,6-dioxo-7H-purin-7-ide; C26H30ClN5O3; 606-90-6
MeN
N
N
N
O
O
Me
Cl
H O
NMe•
Piracetam pi·ra·së·tam2-(2-Oxopyrrolidin-1-yl)acetamide; C6H10N2O2; 7491-74-9; NOOTROPIL
Central nervous system stimulant
NNH2
OO
Pirazolac pi·ra·zö·lak4-(4-Chlorophenyl)-1-(4-fluorophenyl)pyrazol-3-ylacetic acid; C17H12ClFN2O2;71002-09-0Analgesic; anti-inflammatory
N
N COOH
F Cl
�Pirbuterol per·bü·te·rol2-tert-Butylamino-1-(5-hydroxy-6-hydroxymethyl-2-pyridyl)ethanol; C12H20N2O3;38677-81-5Pibuterol Acetate 65652-44-0; EXIREL AREOSOL INHALATION
Pibuterol Hydrochloride 65652-44-0; EXIREL CAPSULES and SYRUP
Beta-adrenoceptor agonist
NH OH
NHBu t
HO
HO
and enantiomer
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3-167Pirenperone pi·ren·pe·rön
3-[2-[4-(4-Fluorobenzoyl)piperidino]ethyl]-2-methylpyrido[1,2-a]pyrimidin-4-one; C23H24FN3O2; 75444-65-4; R47465Antipsychotic
N
N
N
O
Me
O
F
�Pirenzepine pi·ren·ze·pën5,11-Dihydro-11-(4-methylpiperazin-1-ylacetyl)pyrido[2,3-b][1,4]benzodiazepin-6-one; C19H21N5O2; 28797-61-7Pirenzepine Hydrochloride 29868-61-7; GASTROZEPIN
Anticholinergic
HN
NN
O
O N
NMe
Piretanide pi·re·ta·nïd4-Phenoxy-3-pyrrolidin-1-yl-5-sulfamoylbenzoic acid; C17H18N2O5S;55837-27-9; Hoe 118; S73 4118; ARELIX
Diuretic
O
COOH
SO2NH2
N
Piridoxilate pi·ri·doks·i·lät2-(5-Hydroxy-4-hydroxymethyl-6-methyl-3-pyridylmethoxy)glycolic acid¾ 2-[4,5-bis(hydroxymethyl)-2-methyl-3-pyridyloxy]glycolic acid (1:1); C20H26N2O12; 24340-35-0Vasodilator
HN Me
O COO_
OH
CH2OH
HOH2C
+
+
HN
CH2OH
HO
Me
O COO_
OH
+
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3-168Pirimiphos-ethyl (BAN) pi·rim·i·fos- ë·thïl
O-(2-Diethylamino-6-methylpyrimidin-4-yl) O,O-diethyl phosphorothioate;C13H24N3O3PS; 23505-41-1Insecticide
P
S
OEt
O
NN
NEt2
Me OEt
Piritramide pi·ri·tra·mïd1-(3-Cyano-3,3-diphenylpropyl)-4-piperidinopiperidine-4-carboxamide;C27H34N4O; 302-41-0Opioid analgesic
N
NH
CONH2CN
Pirodavir pi·ro·da·veerEthyl 4-{2-[1-(6-methylpyridazin-3-yl)-4-piperidyl]ethoxy}benzoate; C21H27N3O3;124436-59-5; R77975Antiviral
NN
N
O
COOEt
Me
�Piroxicam pi·roks·i·kam4-Hydroxy-2-methyl-N-2-pyridyl-2H-1,2-benzothiazine-3-carboxamide1,1-dioxide; C15H13N3O4S; 36322-90-4; FELDENE
Analgesic; anti-inflammatory
N HN
OOH
MeSOO
N
Piroximone pi·roks·i·mön4-Ethyl-5-isonicotinoyl-4-imidazolin-2-one; C11H11N3O2; 84490-12-0;MDL 19205Cardiac stimulant
N N
N
O
O
Et
H
H
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3-169Pirprofen per·prö·fen
2-[3-Chloro-4-(3-pyrrolin-1-yl)phenyl]propionic acid; C13H14ClNO2;31793-07-4; C21524-SuAnalgesic; anti-inflammatory
N
MeH
COOHCl
and enantiomer
�Pirquinozol2-(Hydroxymethyl)pyrazolo[1,5-c]quinazolin-5(6H)-one; C11H9N3O2; 65950-99-4Antiallergic
NN
N O
OH
H
Pituitary Extract (Posterior) (BAN)A powder obtained by acetone extraction from the defatted posterior pituitarylobes of mammals possessing oxytocin and anti-diuretic activities
Pivampicillin pi·vam·pi·si·linPivaloyloxymethyl (6R)-6-(a-D-phenylglycylamino)penicillanate; C22H29N3O6S;33817-20-8�Pivampicillin Hydrochloride 26309-95-5; PONDOCILLIN*Antibiotic
N
NO
H2N H
O
S
H
Me
Me
H H
O O
O O
Me
Me
Me
H
�Pivhydrazine (BAN)2¢-Benzylpivalohydrazide; C12H18N2O; 306-19-4
NN
Me
O
MeMeH
H
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3-170Pivmecillinam piv·me·si·li·nam
Pivaloyloxymethyl (6R)-6-(perhydroazepin-1-ylmethyleneamino)penicillanate;amdinocillin pivoxil (USAN); C21H33N3O5S; 32886-97-8�Pivmecillinam Hydrochloride PONDOCILLIN*, SELEXID
Antibiotic
NO
S
H
Me
Me
H H
NN
O OMe
O O
MeMe
Pivsulbactam (BAN) piv·sul·bak·tam(1) Pivaloyloxymethyl penicillanate 1,1-dioxide; (2) Pivaloyloxymethyl (2S,5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylate 1,1-dioxide;sulbactam pivoxil (USAN); C14H21NO7S; 69388-79-0;CP-47904Beta-lactamase inhibitor
N
S
O
H O
O
H
Me
O OMe
O O
MeMeMe
Pizotifen pi·zo·ti·fen9,10-Dihydro-4-(1-methylpiperidin-4-ylidene)-4H-benzo[4,5]cyclohepta[1,2-b]thiophene; pizotyline (USAN); C19H21NS; 15574-96-6�Pizotifen Malate 5189-11-7; SANOMIGRAN
Prophylaxis of migraine
S
N
Me
Plasmin (BAN) plaz·minThe proteolytic enzyme derived from the activation of plasminogen which convertsfibrin into soluble products; fibrinase; fibrinolysin (human) (pINN); 9004-09-5Enzyme
Plasminogen (BAN) plaz·mi·nö·jenThe specific substance derived from plasma which, when activated, has theproperty of lysing fibrinogen, fibrin and some other proteins.
�Plicamycin plik·a·mï·sinA glucosidic antitumour antibiotic produced by Streptomyces argillaceus, S. plicatusand S. tanashiensis; mithramycin; C52H76O24; 18378-89-7Cytotoxic
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3-171Podophyllotoxin (BAN) pö·dö·fï·lö·toks·in
(5R,5aR,8aR,9R)-5,5a,6,8,8a,9-Hexahydro-9-hydroxy-5-(3,4,5-trimethoxyphenyl)furo[3¢4¢:6,7]naphtho[2,3-d]-1,3-dioxol-6-one; C22H22O8; 518-28-5; CONDYLINE; WARTICON
Treatment of warts
O
OO
OHH
O
OMeMeO
OMe
H H
H
�Poldine Metilsulfate (BAN) pol·dën2-Benziloyloxymethyl-1,1-dimethylpyrrolidinium methylsulfate; C22H29NO7S; 545-80-2; NACTON
Anticholinergic
O N
O
HO
H MeMe
+
CH3SO4_
Polidexide (BAN) pol·ë·deks·ïdDextran cross-linked with 1-chloro-2,3-epoxypropane and O-substituted with 2-diethylamino and 2-[2-(diethylaminoethyl)-N,N-diethylammonio]ethyl groups;56227-39-5Polidexide SulphateHypolipidaemic
Polidronium Chloride po·lë·drö·në·uma-{(E)-4-[Tris(2-hydroxyethyl)ammonio]but-2-enyl}-w-[tris(2-hydroxyethyl)ammonio]poly[(dimethyliminio)(E)-but-2-enylene chloride]dichloride; C16H36Cl2N2O6 (C6H12ClN)n; 75345-27-6; POLYQUAT;ONAMER MAntimicrobial
N N
Me
Me
OH
OH
OH
NHO
OH
H
+ +
n
(n + 2)Cl_
+
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3-172Poliglecaprone po·lë·gle·ka·prön
Poly[oxy(1-oxoethylene)]-block-poly[oxy(1-oxohexamethylene)];[C2H2O2]m[C6H10O2]n; 41706-81-4Synthetic absorbable suture
OO
OO m n
Polihexanide (polyhexanide) po·lë·heks·a·nïdPoly(1-hexamethylenebiguanide hydrochloride); 32289-58-0; ¨ sAPPHIRE; ¨ STARCARE
BLUE
Antibacterial
HN
HN
HN [CH2]5
NH NH
,HCl
n
Poloxalene pol·oks·a·lënA block co-polymer of oxyethylene and oxypropylene having a molecular weight ofapproximately 3000; 9003-11-6; ¨BLOAT GUARD
Non-ionic surfactant
Poloxamer pol·oks·a·mera-Hydro-w-hydroxypoly(oxyethylene)poly(oxypropylene)-poly(oxyethylene) blockcopolymerEach poloxamer name is followed by a number, e.g., poloxamer 188, 331, 407 etc.The first two digits multiplied by 100 correspond to the approximate averagemolecular weight of the poly(oxypropylene) portion; the third digit multiplied by 10corresponds to the percentage by weight of the poly(oxyethylene) portion; 9003-11-6; AILAX*; CODALAX*;Non-ionic surfactant
O O
Me
O OHa ab
Poloxyl Lanolin (BAN) po·loks·ïlA polyoxyethylene condensation product of anhydrous lanolin.Emollient
Polycarbophil po·lë·kar·bö·filPolyacrylic acid cross-linked with divinyl glycol; 9003-97-8Polycarbophil Calcium AHR-3260 BAntidiarrhoeal; laxative
Polydioxanone (BAN) po·lë·dï·oks·a·nönPoly[oxy(1-oxoethylene)oxyethylene]; (C4H6O3)n; 31621-87-1; PDSSynthetic absorbable suture
OO
O n
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3-173Polyestradiol Phosphate po·lë·ës·tra·dï·ol
A polyester of estra-1,3,5(10)-triene-3,17b-diol and phosphoric acid;28014-46-2; ESTRADURIN*Oestrogen
Polygeline po·li·je·lënA polymer prepared by cross-linking polypeptides derived from denatured gelatinwith a di-isocyanate to form urea bridges; 9015-56-9; HAEMACCEL*Plasma volume expander
Polyglactin (BAN) pol·ë·glak·tinLactic acid polyester with glycollic acid; 26780-50-7Synthetic absorbable suture
Polyglycolic Acid pol·ë·glï·ko·likPoly(glycollic acid); 26009-03-0; DEXON
Synthetic absorbable suture
O
O
n
Polyglyconate (BAN) pol·ë·glï·kö·nätA co-polymer of 1,4-dioxane-2,5-dione and trimethylene carbonate;75734-93-9; MAS-01Synthetic absorbable suture
O
O O
O
O O
O m n
Polyhexanide see Polihexanide
Polymyxin B (polymyxin) po·lë·miks·inAntimicrobial polypeptides produced by strains of Bacillus polymyxa; polymyxin E isColistin; 1404-26-8�Polymyxin B Sulphate 1405-20-5; ALCON*; GREGODERM*; NEOSPORIN*; OTOSPORIN*;¨PNP EAR DROPS*; POLYFAX*; POLYTRIM*; TERRA-CORTRIL*Antibiotic
Polynoxylin po·lë·noks·i·linPoly{[bis(hydroxymethyl)ureylene]methylene}; 9011-05-6; ANAFLEX;Antibacterial
Polyoxyl 8 Stearate see Macrogol 8 Stearate
Polyoxyl 40 Stearate see Macrogol 40 Stearate
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3-174Polysorbate po·lë·sor·bät
Polyoxyethylene derivatives of cyclic sorbitol anhydrides partially esterified with afatty acidThe numbered polysorbates indicated below refer to the following compounds: eg�polysorbate 20: polyoxyethylene 20 sorbitan monolaurate; 9005-64-5 SORBESTER
Q12; TWEEN 20polysorbate 40: polyoxyethylene 20 sorbitan monopalmitate; 9005-66-7; SORBESTER
Q16; TWEEN 40; UNGUENTUM MERCK*�polysorbate 60: polyoxyethylene 20 sorbitan monostearate; 9005-67-8; MASSE*;SORBESTER Q18; TWEEN 60polysorbate 65: polyoxyethylene 20 sorbitan tristearate; 9005-71-4; SORBESTER Q38;TWEEN 65�polysorbate 80: polyoxyethylene 20 sorbitan mono-oleate; 9005-65-6; SORBESTER
Q17; TWEEN 80polysorbate 85: polyoxyethylene 20 sorbitan trioleate; 9005-70-3; SORBESTER Q37;TWEEN 85
polyoxyethylene 20 sorbitan corresponds to tris(polyethylene glycol 300) sorbitanethers.Non-ionic surfactants
�Polythiazide po·lë·thï·a·zïd(RS)-6-Chloro-3,4-dihydro-2-methyl-3-(2,2,2-trifluoroethylthiomethyl)-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; C11H13ClF3N3O4S3;346-18-9; NEPHRIL
Diuretic
H2N NMe
NH
ClS CF3
SOO
SOO
Hand enantiomer
Polyvinox (BAN) po·lë·vï·noksPoly(1-butoxyethylene); Shostakovsky BalsamSkin application
Ponalrestat po·nal·re·stat3-(4-Bromo-2-fluorobenzyl)-3,4-dihydro-4-oxophthalazin-1-ylacetic acid;C17H12BrFN2O3; 72702-95-5Aldose reductase inhibitor
N
N
Br
FO
COOH
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3-175Poractant Alfa (BAN) por·rak·tant
An extract of porcine lung containing not less than 90% of phospholipids, about1% of hydrophobic proteins (SP-B and SP-C) and about 9% of other lipids;129069-19-8; CUROSURF
Treatment of respiratory distress syndrome
Porfimer Sodium por·fi·merPolyporphyrin oligomer containing ester and ether linkages; 87806-31-3;CL 184,116Cytotoxic (photoradiation therapy photosensitiser)
�Porfiromycin(1S,2S,9S,9aR)-[7-Amino-2,3,5,8,9,9a-hexahydro-9a-methoxy-6-methyl-1,2-(methylepimino)-5,8-dioxo-1H-pyrrolo[1,2-a]indol-9-yl]methyl carbamate;C16H20N4O5;801-52-5
NNMe
O
O
H2N
Me
OMe
O
NH2O
H
H
Poskine pos·kën(1S,3s,5R,6R,7S)-6,7-Epoxytropan-3-yl (S)-O-propionyltropate; C20H25NO5; 585-14-8Sedative
NO
Me
O OCH3
O O
H
Potassium Menaphthosulphate see Menadiol Potassium Sulfate
�Povidone po·vi·dönPoly(2-oxopyrrolidin-1-ylethylene); polyvidone (pINN); 9003-39-8; DISADINE
Plasma volume expander
N O
CHH CH2 Hn
�Povidone¾¾¾¾¾ Iodine (BAN)Poly(2-oxopyrrolidin-1-ylethylene)iodine complex; iodinated povidone; 25655-41-8;BETADINE; ̈ PEVIDINE; PRAGMATER
Anti-infective
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3-176Practolol prak·to·lol
4¢-(2-Hydroxy-3-isopropylaminopropoxy)acetanilide; C14H22N2O3;6673-35-4Beta-adrenoceptor antagonist
O NHPr i
AcHN
H OH
and enantiomer
Prajmalium Bitartrate praj·mal·ë·umN-Propylajmalinium hydrogen tartrate; C27H38N2O8; 2589-47-1Antiarrhythmic
NN
HO
Me
Prn
OH
Et
H
HHOOC
COOHOHH
H OH
,
Pralidoxime pra·li·doks·ëm2-Hydroxyiminomethyl-1-methylpyridinium (cation); C7H9N2O;495-94-3Pralidoxime Iodide 94-63-3Cholinesterase reactivator
N
CH3
NOH+
Pramipexole pra·mi·peks·ôl(S)-2-Amino-4,5,6,7-tetrahydro-1,3-benzothiazole-6-yl(propyl)amine; C10H17N3S;104632-26-0Pramipexole Hydrochloride (2HCl) 104632-25-9; SND 919 c1 2YDopamine D3-receptor agonist; antiparkinsonian
S
NNH2
PrnHNH
Pramiverine pra·mi·ver·rën(4,4-Diphenylcyclohexyl)isopropylamine; C21H27N; 14334-40-8Antispasmodic
HN
Me
Me
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3-177Pramocaine (pramoxine) pra·mö·kän
4-[3-(4-Butoxyphenoxy)propyl]morpholine; pramocaine (rINN); C17H27NO3; 140-65-8Pramocaine Hydrochloride 637-58-1; ANUGESIC*; PROCTOFOAM HC*Local anaesthetic
O
O N
Me
O
Prampine pram·pën(1R,3r,5S)-Tropan-3-yl (S)-O-propionyltropate; C20H27NO4; 7009-65-6Treatment of peptic ulcer
NMe
O OCH3
O O
H
Pranlukast pran·loo·kastN-[4-Oxo-2-(1H-tetrazol-5-yl)-4H-chromen-8-yl]-4-(4-phenylbutoxy)benzamide;C27H23N5O4; 103177-37-3; SB 205312; ONO-1078Leukotriene-receptor antagonist; antiasthmatic
NH
O
O
O
O NH
N N
N
Pravastatin pra·va·sta·tin(3R,5R)-7-{(1S,2S,6S,8S,8aR)-1,2,6,7,8,8a-Hexahydro-6-hydroxy-2-methyl-8-[(S)-2-methylbutyryloxy]-1-naphthyl}3,5-dihydroxyheptanoic acid; C23H36O7;81093-37-0Pravastatin Sodium 81131-70-6; LIPOSTAT
Hypolipidaemic
HO
O
O
H
HO
H
HOOCH
HMe
HH
HMeH
Me
OH
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3-178�Prazepam prä·ze·pam
7-Chloro-1-(cyclopropylmethyl)-1,3-dihydro-5-phenyl-1,4-benzodiazepin-2-one;C19H17ClN2O; 2955-38-6Anxiolytic
N
NCl
O
�Praziquantel prä·zi·kwan·tel2-Cyclohexylcarbonyl-1,2,3,6,7,11b-hexahydropyrazino[2,1-a]isoquinolin-4-one;C19H24N2O2; 55268-74-1; ̈ DRONIT
Anthelmintic
N
N
O
OH
and enantiomer
�Prazitone(RS)-5-Phenyl-5-(2-piperidylmethyl)barbituric acid; C16H19N3O3; 2409-26-9
and enantiomer
NH
NHHN
O
OO
H
Prazosin prä·zö·sin2-[4-(2-Furoyl)piperazin-1-yl]-6,7-dimethoxyquinazolin-4-ylamine; C19H21N5O4;19216-56-9�Prazosin Hydrochloride 19237-84-4; HYPOVASE
Alpha-adrenoceptor antagonist
OO
N
N
N
NMeO
MeO
NH2
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3-179Prednisolamate pred·ni·so·la·mät
11b,17a-Dihydroxy-3,20-dioxopregna-1,4-dien-21-yl diethylaminoacetate;prednisolone 21-diethylaminoacetate; C27H39NO6; 5626-34-6Corticosteroid
Me
HMe
O
H H
O
OHHOO
NEt2
O
�Prednisolone pred·nis·o·lön11b,17a,21-Trihydroxypregna-1,4-diene-3,20-dione; C21H28O5; 50-24-8; ANACAL*;DELTACORTRIL; DELTASTAB; ̈ FLAMASONE; MINIMS PREDNISOLONE; ̈ MULTIMAST*;¨MULTIJECT*; ̈ NISOLONE; ̈ OPTICORTENOL*; ̈ PHENCOCYCLINE*; PRECORTISYL;¨PREDNICARE; ̈ PREDNIVET
�Prednisolone Acetate 52-21-1; PRED FORTE; SUROLAN*Prednisolone Hexanoate SCHERIPROCT*Prednisolone Metasulphobenzoate Sodium 630-67-1; PREDENEMA; PREDFOAM
�Prednisolone Pivalate 1107-99-9�Prednisolone Sodium Phosphate 125-02-0; PREDNESOL; PREDSOL
Corticosteroid
O
Me
H H
H
MeHO
OHO
OH
�Prednisolone Steaglate pred·ni·so·lön stë·a·glät11b,17a-Dihydroxy-3,20-dioxopregna-1,4-dien-21-yl stearoylglycollate; C41H64O8;5060-55-9Corticosteroid
O
Me
H H
H
MeHO
OO
OH
O C17H35
O
O
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3-180�Prednisone pred·nis·ön
17a,21-Dihydroxypregna-1,4-diene-3,11,20-trione; C21H26O5; 53-03-2Prednisone Acetate 125-10-0Corticosteroid
O
Me
H H
H
Me OHO
OHO
Prednylidene pred·nï·li·dën11b,17a,21-Trihydroxy-16-methylenepregna-1,4-diene-3,20-dione; C22H28O5; 599-33-7Corticosteroid
Me
HO
H H
OH
OH
O
Me
H CH2
O
�Pregnenolone3b-Hydroxypregn-5-en-20-one; C21H32O2; 145-13-1
Me
Me
H
H H
HO
O Me
H
Premazepam prë·mä·ze·pam1,2,3,7-Tetrahydro-6,7-dimethyl-5-phenylpyrrolo[3,4-e][1,4]diazepin-2-one;C15H15N3O; 57435-86-6; L 12181; DL-181-IT; MDL-181Anxiolytic
N
HN
NMe
Me
O
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3-181Prenalterol pre·nal·te·rol
(S)-1-(4-Hydroxyphenoxy)-3-isopropylaminopropan-2-ol; C12H19NO3; 57526-81-5Prenalterol Hydrochloride 61260-05-7Beta-adrenoceptor agonist
HO
O N Me
Me
OHH H
Prenylamine pre·nï·la·mën(RS)-2-Benzhydrylethyl(a-methylphenethyl)amine; C24H27N; 390-64-7Prenylamine Lactate 69-43-2Vasodilator
HN
H Me
and enantiomer
�Pretamazium Iodide4-(Biphenyl-4-yl)-3-ethyl-2-[4-(pyrrolidin-1-yl)styryl]-1,3-thiazolium iodide;C29H29IN2S; 24840-59-3
N
SN
Et
+I_
�Prilocaine prï·lö·kän2-Propylaminopropiono-o-toluidide; C13H20N2O; 721-50-6�Prilocaine Hydrochloride 1786-81-8; CITANEST; EMLA*Local anaesthetic
N
O
HMe Me
NHPrn
and enantiomer
H
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3-182Primaquine prim·a·kwën
4-Amino-1-methylbutyl(6-methoxy-8-quinolyl)amine; C15H21N3O;90-34-6�Primaquine Phosphate 63-45-6Antimalarial
and enantiomer
N
MeO
HNNH2
MeH
Primidolol pri·mï·do·lol1-[2-(2-Hydroxy-3-o-tolyloxypropylamino)ethyl]-5-methyluracil; C17H23N3O4;67227-55-8Beta-adrenoceptor antagonist
O NN NH
Me O
O
Me
HO HH
and enantiomer
�Primidone pri·mi·dön5-Ethyl-5-phenylperhydropyrimidine-4,6-dione; C12H14N2O2; 125-33-7; MYSOLINE
Anticonvulsant
NH
NO
O
Et
H
Pristinamycin pris·ti·na·mï·sinAntimicrobial substances produced by Streptomyces pristina spiralis;11006-76-1; certain components are identical with some constituents of mikamycin,ostreogrycin and virginiamycin
Prizidilol pri·zi·di·lol1-tert-Butylamino-3-[2-(6-hydrazinopyridazin-3-yl)phenoxy]propan-2-olC17H25N5O2; 59010-44-5Beta-adrenoceptor antagonist; vasodilator
and enantiomer
OHHO
NHBut
H2N
HN N
N
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3-183�Probenecid prö·be·ne·sid
4-(Dipropylsulfamoyl)benzoic acid; C13H19NO4S; 57-66-9; BENEMID
Uricosuric
Prn2N
S
COOH
O O
�Probucol prö·bü·kol4,4¢-Isopropylidenedithiobis(2,6-di-tert-butylphenol); C31H48O2S2;23288-49-5Hypolipidaemic
S S
Me MeHO OH
Bu t
Bu tBu t
Bu t
Procainamide prö·kä·na·mïd4-Amino-N-(2-diethylaminoethyl)benzamide; C13H21N3O; 51-06-9;�Procainamide Hydrochloride 614-39-1; PROCAINAMIDE DURULES; PRONESTYL
Myocardial depressant; antiarrythmic
H2N
NNEt2
O
H
Procaine prö·kän2-Diethylaminoethyl 4-aminobenzoate; C13H20N2O2; 59-46-1�Procaine Hydrochloride 51-05-8; ̈ WILLCAIN*Local anaesthetic
H2N
ONEt2
O
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3-184�Procaine Benzylpenicillin/ Procaine Penicillin
2-(4-Aminobenzoyloxy)ethyldiethylammonium (6R)-6-(2-phenyl-acetamido)penicillanate; procaine penicillin G; C29H38N4O6S; 54-35-3; BICILLIN*;¨DEPOCILLIN; ̈ ECONAPEN; ̈ LENTICILLIN; ̈ LENTRAX*; ̈ MICROFAC*; ̈ MYLIPEN;¨NOROCILLIN; ¨PEN-3-MAST; ¨PROPEN*; component in many other veterinarypreparationsAntibiotic
HN
NOO
S
H COO_
Me
Me
H H
H2N
ONHEt2
O+
�Procarbazine prö·kar·ba·zënN-Isopropyl-a-(2-methylhydrazino)-p-toluamide; C12H19N3O; 671-16-9Cytotoxic
N
OMe
Me
NHNHMeH
Procaterol prö·ka·te·rol8-Hydroxy-5-[(1R*,2S*)-1-hydroxy-2-isopropylaminobutyl]-2-quinolone;C16H22N2O3; 60443-17-6; 72332-33-3Procaterol Hydrochloride 59828-07-8; OPC-2009Beta-adrenoceptor agonist
CH3HN
H OH
H NHPr i
HO
O
and enantiomer
Prochlorperazine prö·klor·pe·ra·zën2-Chloro-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine; C20H24ClN3S; 58-38-8�Prochlorperazine Maleate 84-02-6; BUCCASTEM; STEMETIL (rectal & topical)�Prochlorperazine Mesilate 5132-55-8; STEMETIL (oral & parenteral)Antiemetic
N
S
N
NMe
Cl
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3-185�Proclonol
a,a-Bis(p-chlorophenyl)cyclopropylmethanol; C16H14Cl2O; 14088-71-2Acaricide; fungicide
OH
ClCl
and enantiomer
Procromil (BAN) prö·kro·mil6,7,8,9-Tetrahydro-4-oxo-10-propyl-4H-benzo[g]chromene-2-carboxylic acid;C17H18O4; 60400-86-4Prophylaxis of allergic conditions
O
O
COOH
Pr n
Procyclidine prö·sï·kli·dën(RS)-1-Cyclohexyl-1-phenyl-3-(pyrrolidin-1-yl)propan-1-ol; C19H29NO; 77-37-2Procyclidine Hydrochloride 1508-76-5; ARPICOLIN; KEMADRIN
Anticholinergic
N
OH
and enantiomer
�Profadol3-(1-Methyl-3-propylpyrrolidin-3-yl)phenol; C14H21NO; 428-37-50
OH
NMe
Prn
and enantiomer
Profenamine (ethopropazine) prö·fen·a·mën(RS)-[1-Methyl-2-(phenothiazin-10-yl)ethyl]diethylamine; C19H24N2S; 522-00-9Anticholinergic
N
S NEt2
HMe
and enantiomer
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3-186Progabide prö·ga·bïd
4-(4¢-Chloro-5-fluoro-2-hydroxybenzhydrylideneamino)butyramide;C17H16ClFN2O2; 62666-20-0; SL 76 002Anticonvulsant
N CONH2
OH
F
Cl
�Progesterone prö·je·ster·rönPregn-4-ene-3,20-dione; C21H30O2; 57-83-0; CYCLOGEST; ̈ EAZI-BREED; GESTONE;¨NYMFALON*; ̈ PRID*Progestogen
O
Me
H H
H
MeCH3O
H
Proglumetacin prö·gloo·me·ta·sin3-{4-[2-(1-p-Chlorobenzoyl-5-methoxy-2-methylindol-3-ylacetoxy)ethyl]piperazin-1-yl}propyl 4-benzamido-N,N-dipropylglutaramate; C46H58ClN5O8; 57132-53-3Analgesic; anti-inflammatory
N
O
N
N
O
Me
O
Cl
MeO
O
O
Prn2N O
O
HN
H
and enantiomer
Proglumide prö·gloo·mïd4-Benzamido-N,N-dipropylglutaramic acid; C18H26N2O4; 6620-60-6Histamine H1-receptor antagonist
N
O
COOH
NPrn2O
H
H
and enantiomer
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3-187Proguanil prö·gwa·nil
1-(4-Chlorophenyl)-5-isopropylbiguanide; C11H16ClN5; 500-92-5�Proguanil Hydrochloride 637-32-1; MALARONE*; PALUDRINE
Antimalarial
N N NHPr i
ClNH NH
H H
Proheptazine prö·hep·ta·zën(RS)-1,3-Dimethyl-4-phenylperhydroazepin-4-yl propionate; C17H25NO2;77-14-5Opioid analgesic
NMe
Me
Et COO
and enantiomer
Proligestone prö·li·jes·tön14a,17a-Propylidenedioxypregn-4-ene-3,20-dione; C24H34O4;23873-85-0; ̈ COVINAN; ̈ DELVOSTERON*Progestogen
O
Me
H O
H
MeCH3O
O
Et
�Prolintane prö·lin·tän1-(a-Propylphenethyl)pyrrolidine; C15H23N; 493-92-5Central nervous system stimulant
N
CH3
H
and enantiomer
Promazine prö·ma·zënDimethyl(3-phenothiazin-10-ylpropyl)amine; C17H20N2S; 58-40-2Promazine Hydrochloride 53-60-1; SPARINE
Hypnotic; anxiolytic
N
S
NMe2
Cl
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3-188Promethazine prö·me·tha·zën
Dimethyl(1-methyl-2-phenothiazin-10-ylethyl)amine; C17H20N2S;60-87-7�Promethazine Hydrochloride 58-33-3; MEDISED*; PAMERGAN*; PHENERGAN;SOMINEX; TIXYLIX NIGHT-TIME*Histamine H1-receptor antagonist
N
S
NMe2
Cl
H Me
and enantiomer
�Promethazine TeoclatePromethazine salt of 8-chlorotheophylline; C24H27ClN6O2S; 17693-51-5; AVOMINE
Histamine H1-receptor antagonist
Promethoestrol see Methestrol
�Promoxolane (promoxolan)(RS)-2,2-Di-isopropyl-1,3-dioxolan-4-ylmethanol; C10H20O3; 470-43-9
O
OOH
HPr i
Pr i
and enantiomer
�Pronetalol (pronethalol)2-Isopropylamino-1-(2-naphthyl)ethanol; C15H19NO; 54-80-8
NHPr iH OH
and enantiomer
Propacetamol prö·pa·set·a·mol4-Acetamidophenyl diethylaminoacetate; C14H20N2O3; 66532-85-2Analgesic; antipyretic
AcHN
O
O
NEt2
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3-189Propafenone prö·pa·fe·nön
2¢-(2-Hydroxy-3-propylaminopropoxy)-3-phenylpropiophenone; C21H27NO3;54063-53-5Propafenone Hydrochloride 34183-22-7; ARYTHMOL
Antiarrhythmic
O NHPrn
O
H OH
and enantiomer
Propamidine prö·pa·mi·dën4,4¢-Trimethylenedioxydibenzamidine; C17H20N4O2; 104-32-5Propamidine Isethionate 140-63-6; BROLENE EYE DROPS; GOLDEN EYE DROPS
Antiseptic
NH2
HN
O
NH2
NH
O
�PropanididPropyl 4-diethylcarbamoylmethoxy-3-methoxyphenylacetate; C18H27NO5; 1421-14-3
ONEt2
O
OMe O
O
H3C
�Propantheline Bromide prö·pan·the·lënDi-isopropylmethyl-2-(xanthen-9-ylcarbonyloxy)ethylammonium bromide;C23H30BrNO3; 50-34-0; PRO-BANTHINE
Anticholinergic
O
OONPr i
2
Me
+
Br_
Propatylnitrate prö·pa·tïl·nï·trät1,1,1-Tris(nitratomethyl)propane; C6H11N3O9; 2921-92-8Vasodilator
ONO2
ONO2
H3C
O2NO
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3-190Propentofylline prö·pen·to·fi·lën
3-Methyl-1-(5-oxohexyl)-7-propyl-7H-purine-2,6(1H,3H)-dione; C15H22N4O3;55242-55-2 ̈ VIVITONIN
Adenosine transport blocker and phosphodiesterase inhibitor; treatment of dementia
N
N
N
N
O
O
Me
H3C
PrnO
�ProperidineIsopropyl 1-methyl-4-phenylpiperidine-4-carboxylate; C16H23NO2;561-76-2Opioid analgesic
NMe
COOPr i
Propetamphos (BAN) prö·pe·tam·fosIsopropyl (E)-3-[(ethylamino)(methoxy)phosphinothio-oxy]but-2-enoate;C10H20NO4PS; 31218-83-4; ECTOMORT; FLYTE
Parasiticide (veterinary)
P
SEtHN
MeO O
H
Me
O Me
MeO
Propicillin prö·pi·si·lin(6R)-6-(2-Phenoxybutyramido)penicillanic acid; C18H22N2O5S; 551-27-9Propicillin Potassium 1245-44-9Antibiotic
*HN
NOO
S
H COOH
Me
Me
H H
O
Et H
and enantiomer at C*
Propiolactone prö·pë·ö·lak·tönPropiono-3-lactone; C3H4O2; 57-57-8Anti-infective
OO
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3-191Propiomazine prö·pë·ö·ma·zën
1-{10-[2-(Dimethylamino)propyl]phenothiazin-2-yl}propan-1-one; C20H24N2OS;362-29-8Hypnotic; anxiolytic
N
S
NMe2
H Me
CH3
O
and enantiomer
Propiram prö·pi·ramN-(1-Methyl-2-piperidinoethyl)-N-(2-pyridyl)propionamide; C16H25N3O; 15686-91-6Propiram Fumarate 13717-04-9Opioid analgesic
N NN
CH3O
H Me
and enantiomer
Propiverine prö·pi·ve·rën1-Methyl-4-piperidyl diphenyl(propoxy)acetate; C23H29NO3; 60569-19-9; BUP-4Propiverine Hydrochloride 54556-98-8; DETRUNORM
Antispasmodic; treatment of urinary disorders
O
NMeO
OPrn
Propofol prö·po·fol2,6-Di-isopropylphenol; C12H18O; 2078-54-8; DIPRIVAN; RAPINOVET
Anaesthetic
OH
Pr i Pr i
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3-192Propoxur prö·poks·ûr
2-Isopropoxyphenyl methylcarbamate; C11H15NO3; 114-26-1Ectoparasiticide (veterinary)
O
OPri
NHMeO
Propranolol prö·pran·o·lol1-Isopropylamino-3-(1-naphthyloxy)propan-2-ol; C16H21NO2; 525-66-6�Propranolol Hydrochloride 318-98-9; ANGILOL; APSOLOL; BEDRANOL; BERKOLOL;BETA-PROGRANE; HALF-INDERAL; INDERAL; INDERETIC*; INDEREX*; LOPRANOL; PROBETA;PROPANIX
Beta-adrenoceptor antagonist
O NHPr iOHH
and enantiomer
�Propyl DocetrizoatePropyl 3-diacetylamino-2,4,6-tri-iodobenzoate; C14H14I3NO4; 5579-08-8
COOPrn
II
I
NAc2
Propylhexedrine prö·pïl·heks·e·drën2-Cyclohexyl-1-methylethyl(methyl)amine; C10H21N; 3595-11-7Central nervous system stimulant
NHMe
H Me
and enantiomer
Propyliodone prö·pïl·ï·ö·dönPropyl 1,4-dihydro-3,5-di-iodo-4-oxo-1-pyridylacetate; C10H11I2NO3;587-61-1; DIONOSIL
Contrast medium
NO
CH3
O
I
I
O
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3-193�Propylthiouracil prö·pïl·thï·ö·ûr·ra·sil
2,3-Dihydro-6-propyl-2-thioxopyrimidin-4(1H)-one; C7H10N2OS;51-52-5Antithyroid
NH
N S
O
Prn H
�Propyphenazone prö·pë·fe·na·zön4-Isopropyl-2,3-dimethyl-1-phenyl-3-pyrazolin-5-one; C14H18N2O;479-92-5Analgesic; sedative
NN
Me
O
Me
Pr i
Proquamezine see Aminopromazine
Proquazone pro·kwa·zön1-Isopropyl-7-methyl-4-phenylquinazolin-2(1H)-one; C18H18N2O;22760-18-5Analgesic; anti-inflammatory
N
N
Me
Pr i
O
Prorenoate Potassium prö·ren·ö·ätPotassium 6a,7a-dihydro-17b-hydroxy-3-oxo-3¢H-cyclopropa[6,7]-21,24-dinor-17a-chol-4-en-23-oate; C23H31KO4; 49847-97-4; SC 23992Aldosterone antagonist
O
Me
H
H
H
MeOH
COOK
H
H
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3-194Proscillaridin prö·si·la·ri·din
14-Hydroxy-3b-(a-L-rhamnopyranosyloxy)-14b-bufa-4,20,22-trienolide; C30H42O8;466-06-8Cardiac glycoside
Me
H
H
OH
MeH
O
O
O
O
OHOH
HO
Me
Prostalene pros·ta·lën(1) (±)-Methyl 7-{(1R,2R,3R,5S)-3,5-dihydroxy-2-[(E)-3-hydroxy-3-methyloct-1-enyl]cyclopentyl}hepta-4,5-dienoate; (2) (±)-methyl (13E)-(9S,11R,15R)-9,11,15-trihydroxy-15-methylprosta-4,5,13-trienoate; C22H36O5; 54120-61-5; RS-9390Luteolytic
H
H OHHHO
CCOOMe
HO
CH3
and epimer at C*
*
�Protamine Sulphate (BAN) prö·ta·mën sul·fätA purified mixture of the sulfates of basic peptides prepared from the sperm ormature testes of fish, usually species of Cluperidae or Salmonidae;9009-65-8; PROSULF
�Protamine HydrochlorideAntidote to heparin
Prothionamide see Protionamide
�Prothipendyl prö·thï·pen·dïlDimethyl(3-pyrido[3,2-b][1,4]benzothiazin-10-ylpropyl)amine; C16H19N3S; 303-69-5Antipsychotic
N
SN
NMe2
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3-195Protionamide (prothionamide) prö·tï·on·a·mïd
2-Propylpyridine-4-carbothioamide; C9H12N2S; 14222-60-7Treatment of tuberculosis
N Prn
CSNH2
�Protirelin prö·ti·re·lin1-[N-(5-Oxo-l-prolyl)-L-histidyl]-L-prolinamide; TRH; C16H22N6O4; 24305-27-9;RELEFACT LH-RH/TRH*Thyrotrophin-releasing hormone
oxoPro–His–Pro-NH2
Protokylol prö·tö·kï·lol1-(3,4-Dihydroxyphenyl)-2-(a-methyl-3,4-methylenedioxyphenethylamino)ethanol; C18H21NO5; 136-70-9Beta-adrenoceptor agonist
NHO
HO
OH
Me
O
O
H
* *
mixture of stereoisomers
Protriptyline prö·trip·ti·lën3-(5H-Dibenzo[a,d]cyclohepten-5-yl)propyl(methyl)amine; C19H21N;438-60-8�Protriptyline Hydrochloride 1225-55-4; CONCORDIN
Antidepressant
NHMe
�Proxicromil6,7,8,9-Tetrahydro-5-hydroxy-4-oxo-10-propyl-4H-benzo[g]chromene-2-carboxylic acid; C17H18O5; 60400-92-2
O
O
COOH
OH
Prn
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3-196Proxymetacaine proks·ë·me·ta·kän
2-Diethylaminoethyl 3-amino-4-propoxybenzoate; C16H26N2O3;499-67-2�Proxymetacaine Hydrochloride proparacaine hydrochloride (USAN); 5875-06-9; MINIMS PROXYMETACAINE; OPHTHAINE
Local anaesthetic
PrnO
ONEt2
O
H2N
�Proxyphylline7-(2-Hydroxypropyl)theophylline; C10H14N4O3; 603-00-9Bronchodilator
MeN
N
N
N
O
O
Me
CH3
H OH
and enantiomer
Prucalopride proo·kal·ö·prïd4-Amino-5-chloro-2,3-dihydro-N-[1-(3-methoxypropyl)-4-piperidyl][1]benzofuran-7-carboxamide; C18H26ClN3O3; 179474-18-8
Increase of intestinal motility
NH
N OMeO
H2N
Cl
O
Pseudoephedrine sü·dö·e·fe·drën(+)-(1S,2S)-2-Methylamino-1-phenylpropan-1-ol; C10H15NO; 90-82-4�Pseudoephedrine Hydrochloride 345-78-8; present in many proprietarypreparationsSympathomimetic
NHMeOHH
MeH
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3-197Psilocybine (psilocybin) sï·lö·sï·bën
3-(2-Dimethylaminoethyl)indol-4-yl dihydrogen phosphate; C12H17N2O4P; 520-52-5Psychotomimetic
N
NMe2
O
H
P
O
OH
OH
Pumactant (BAN) pü·mak·tantA mixture of 7 parts by weight of 1,2-dipalmitoyl-sn-glycero(3)phosphocholine(DPPC) and 3 parts by weight of 2-oleoyl-1-palmitoyl-sn-glycero(3)phospho(1)-sn-glycerol (PG); artificial lung surfactant; ALEC
Treatment of respiratory diseases in premature babies
Puromycin pûr·rö·mï·sin(S)-3¢-[2-Amino-3-(4-methoxyphenyl)propionamido]-3¢-deoxy-N,N-dimethyladenosine; C22H29N7O5; 53-79-2Antibiotic
O
NH OH
HO
O
H2N HMeO
N
NN
N
NMe2
Pyrantel pi·ran·tel1,4,5,6-Tetrahydro-1-methyl-2-[(E)-2-(2-thienyl)vinyl]pyrimidine; C11H14N2S;15686-83-6Pyrantel Embonate 22204-24-5;¨ STRONGID
Anthelmintic
N
N
S H
H
Me
�Pyrazinamide pi·ra·zi·na·mïdPyrazine-2-carboxamide; C5H5N3O; 98-96-4; RIFATER*; ZINAMIDE
Antitubercular
N
N CONH2
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3-198�Pyridostigmine Bromide pi·ri·dö·stig·mën
3-Dimethylcarbamoyloxy-1-methylpyridinium bromide; C9H13BrN2O2;101-26-8; MESTINON
Anticholinesterase
N
O NMe2
Me
O+
Br_
Pyridoxine pi·ri·doks·ën5-Hydroxy-6-methylpyridine-3,4-dimethanol; C8H11NO3; 65-23-6�Pyridoxine Hydrochloride Vitamin B6; 58-56-0; BENADON; COMPLOMENT CONTINUS;component in many proprietary preparationsVitamin
N
CH2OH
CH2OH
HO
Me
�Pyrimethamine pi·ri·me·tha·mën5-(4-Chlorophenyl)-6-ethylpyrimidine-2,4-diyldiamine; C12H13ClN4;58-14-0; DARAPRIM; FANSIDAR*; MALOPRIM*Antimalarial
N
N
Cl
Et
NH2
H2N
Pyrimitate pi·ri·mi·tätO-2-Dimethylamino-6-methylpyrimidin-4-yl O,O-diethyl phosphorothioate;C11H20N3O3PS; 5221-49-8Insecticide
P
S
OEt
O
N
NMe2N
Me
OEt
Pyrithidium Bromide see Pyritidium Bromide
Pyrithione Zinc pi·ri·thï·önBis(1-hydroxypyridine-2(1H)-thionato)zinc; C10H8N2O2S2Zn;13463-41-7; an ingredient of several proprietary shampoosAnti-infective
N S
O
2
Zn
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3-199�Pyritidium Bromide (pyrithidium bromide) pi·ri·ti·dë·um
3-Amino-8-(2-amino-1,6-dimethylpyrimidinium-4-ylamino)-6-(4-aminophenyl)-5-methylphenanthridinium dibromide; C26H27Br2N7;14222-46-9Antiprotozoan
HN
N N
NH2
Me
MeN
H2N
Me
H2N
+
+ 2Br_
Pyritinol pi·ri·ti·nol5,5¢-Dihydroxy-6,6¢-dimethyl-3,3¢-dithiodimethylenebis(4-pyridylmethanol);C16H20N2O4S2; 1098-97-1Hypnotic; anxiolytic
NS
OH
Me
OHOH
Me
OH
SN
Pyrrobutamine (BAN) pi·rö·bü·ta·mën1-[4-(4-Chlorophenyl)-3-phenylbut-2-enyl]pyrrolidine; C20H22ClN;91-87-7Histamine H1-receptor antagonist
N
Cl
�PyrrocainePyrrolidin-1-ylaceto-2,6-xylidide; C14H20N2O; 2210-77-7
NN
O
Me
Me
H
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3-200Quadazocine kwo·dä·zö·sën
(2R,6S,11S)-1-Cyclopentyl-5-(1,2,3,4,5,6-hexahydro-8-hydroxy-3,6,11-trimethyl-2,6-methano-3-benzazocin-11-yl)pentan-3-one; C25H37NO2; 71276-43-2; WIN44441Quadazocine Mesilate 71276-44-3; WIN 44441-3Opioid antagonist
NMeMe
HO
Me
O
Quadrosilan kwo·drö·sï·lan2,6-cis-Diphenylhexamethylcyclotetrasiloxane; C18H28O4Si; 33204-76-1Treatment of prostatic carcinoma
O
Si
O Si
O
Si
OSi MeMe
Me
Me
Me
Me
Quazepam kwä·ze·pam7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-1,4-benzodiazepine-2-thione; C17H11ClF4N2S; 36735-22-5; Sch 16134Hypnotic
N
NCl
F
CF3S
Quetiapine kwe·tï·a·pën2-{2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethoxy}ethanol;C21H25O2N3SQuetiapine Fumarate 111974-72-2; ICI 204,636; ZM 204,636Dopamine-D2 receptor and 5HT2-serotonin receptor antagonist; antipsychotic
N
S
N
NO
OH
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3-201Quinacillin kwi·na·si·lin
(6R)-6-(3-Carboxyquinoxalin-2-ylcarboxamido)penicillanic acid; C18H16N4O6S;1596-63-0Antibacterial
HN
NO
S
H COOH
Me
Me
H H
N
N
O
COOH
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4-1
�Pyridostigmine Bromide pi·ri·dö·stig·mën3-Dimethylcarbamoyloxy-1-methylpyridinium bromide; C9H13BrN2O2;101-26-8; MESTINON
Anticholinesterase
N
O NMe2
Me
O+
Br_
Pyridoxine pi·ri·doks·ën5-Hydroxy-6-methylpyridine-3,4-diyldimethanol; C8H11NO3; 65-23-6�Pyridoxine Hydrochloride Vitamin B6; 58-56-0; BENADON; COMPLOMENT
CONTINUS; PAXADON; component in many proprietary preparationsVitamin
N
CH2OH
CH2OH
HO
Me
�Pyrimethamine pi·ri·me·tha·mën5-(4-Chlorophenyl)-6-ethylpyrimidine-2,4-diyldiamine; C12H13ClN4;58-14-0; DARAPRIM; FANSIDAR*; MALOPRIM*Antimalarial
N
N
Cl
Et
NH2
H2N
Pyrimitate pi·ri·mi·tätO-2-Dimethylamino-6-methylpyrimidin-4-yl O,O-diethyl phosphorothioate;C11H20N3O3PS; 5221-49-8Insecticide
P
S
OEt
O
N
NMe2N
Me
OEt
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4-2
▼Pyrithidium Bromide pi·ri·thi·dë·um3-Amino-8-(2-amino-1,6-dimethylpyrimidinium-4-ylamino)-6-(4-aminophenyl)-5-methylphenanthridinium dibromide; pyritidium bromide(pINN); C26H27Br2N7;14222-46-9Antiprotozoan
N
NH2
Me
NH2
N
N
N
Me
H2N
Me
+
+
2Br_
H
Pyrithione Zinc pi·ri·thï·önBis(1-hydroxypyridine-2(1H)-thionato)zinc; C10H8N2O2S2Zn;13463-41-7; an ingredient of several proprietary shampoosAnti-infective
N S
O
2
Zn
Pyritinol pi·ri·ti·nol5,5-Dihydroxy-6,6-dimethyl-3,3-dithiodimethylenebis(4-pyridylmethanol);C16H20N2O4S2; 1098-97-1Hypnotic; anxiolytic
NS
OH
Me
OHOH
Me
OH
SN
Pyrrobutamine pi·rö·bü·ta·mën1-[4-(4-Chlorophenyl)-3-phenylbut-2-enyl]pyrrolidine; C20H22ClN;91-87-7Histamine H1-receptor antagonist
N
Cl
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4-3
�PyrrocainePyrrolidin-1-ylaceto-2,6-xylidide; C14H20N2O; 2210-77-7
NN
O
Me
Me
H
�Pyrvinium Pamoate (viprynium embonate)Bis-{6-dimethylamino-2-[2-(2,5-dimethyl-1-phenylpyrrol-3-yl)vinyl]-1-methylquinolinium} 4,4¢-methylenebis(3-hydroxy-2-naphthoate);C75H70N6O6; 3546-41-6
+N
Me
Me
Me
Me2N
N
2
OH
COO__
OOC
OH
Quadazocine kwo·dä·zö·sën(2R,6S,11S)-1-Cyclopentyl-5-(1,2,3,4,5,6-hexahydro-8-hydroxy-3,6,11-trimethyl-2,6-methano-3-benzazocin-11-yl)pentan-3-one; C25H37NO2;71276-43-2; WIN 44441Quadazocine Mesilate 71276-44-3; WIN 44441-3Opioid antagonist
NMeMe
HO
Me
O
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4-4
Quadrosilan kwo·drö·sï·lan2,6-cis-Diphenylhexamethylcyclotetrasiloxane; C18H28O4Si; 33204-76-1Treatment of prostatic carcinoma
O
Si
O Si
O
Si
OSi MeMe
Me
Me
Me
Me
Quazepam kwä·ze·pam7-Chloro-5-(2-fluorophenyl)-1,3-dihydro-1-(2,2,2-trifluoroethyl)-1,4-benzodiazepine-2-thione; C17H11ClF4N2S; 36735-22-5; Sch 16134Hypnotic
N
NCl
F
SF3C
Quetiapine kwe·tï·a·pën2-{2-[4-(Dibenzo[b,f][1,4]thiazepin-11-yl)piperazin-1-yl]ethoxy}ethanol;C21H25O2N3SQuetiapine Fumarate 111974-72-2; SEROQUEL
Dopamine-D2 receptor and 5HT2-serotonin receptor antagonist; antipsychotic
N
S
N
NO
OH
Quinacillin kwi·na·si·lin(6R)-6-(3-Carboxyquinoxalin-2-ylcarboxamido)penicillanic acid;C18H16N4O6S; 1596-63-0Antibacterial
HN
NO
S
H COOH
Me
Me
H H
N
N
O
COOH
![Page 568: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/568.jpg)
4-5
Quinagolide kwi·na·gö·lïd(3S,4aS,10aR)-3-Diethylaminosulfonylamino-1,2,3,4,4a,5,10,10a-octahydro-1-propylbenzo[g]quinolin-6-ol; C20H33N3O3S; NORPROLAC
Quinagolide Hydrochloride 94424-50-7Dopamine D2-receptor agonist
N
NS
NEt2
H
H
Prn
HOH
OO
H
Quinalbarbitone Sodium see Secobarbital Sodium
Quinapril kwi·na·pril(3S)-2-{N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl}-1,2,3,4-tetrahydroisoquinoline-3-carboxylic acid; C25H30N2O5; 85441-61-8;CI-906; ACCUPRO; ACCURETIC*Angiotensin-converting enzyme inhibitor
H COOHH
EtOOCH N
H Me
ON
Quindoxin kwin·doks·inQuinoxaline 1,4-dioxide; C8H6N2O2; 2423-66-7Antibacterial
N
N
O
O
Quinelorane kwi·ne·lor·rän(5aR,9aR)-5,5a,6,7,8,9,9a,10-Octahydro-6-propylpyrido[2,3-g]quinazolin-2-ylamine; C14H22N4; 97466-90-5Quinelorane Hydrochloride 97548-97-5 (2HCl); LY163502Dopamine D2-receptor agonist
N
NN
NH2H
HH3C
![Page 569: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/569.jpg)
4-6
Quinestradol kwi·nës·tra·dol3-Cyclopentyloxyestra-1,3,5(10)-triene-16a,17b-diol; C23H32O3;1169-79-5Oestrogen
O
Me
OH
H
H
H
OH
Quinestrol kwi·nës·trol3-Cyclopentyloxy-19-nor-17a-pregna-1,3,5(10)-trien-20-yn-17b-ol;C25H32O2; 152-43-2Oestrogen
O
Me
H
H
OH
CH
H
Quinethazone kwi·ne·tha·zön(RS)-7-Chloro-2-ethyl-1,2,3,4-tetrahydro-4-oxoquinazoline-6-sulfonamide;C10H12ClN3O3S; 73-49-4Diuretic
H
O O
Cl
O
Et
NH
N
SH2N
H
and enantiomer
Quingestanol kwin·jes·ta·nol3-Cyclopentyloxy-19-nor-17a-pregna-3,5-dien-20-yn-17b-ol; C25H32O2;10592-65-1Progestogen
O
Me
H
H
OH
CHH
H
![Page 570: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/570.jpg)
4-7
Quinidine (BAN) kwi·ni·dën(8R,9S)-6¢-Methoxycinchonan-9-ol; C20H24N2O2; 56-54-2�Quinidine Bisulphate 50-54-4; KIDITARD; KINIDIN DURULES
�Quinidine Sulphate 6591-63-5Antiarrhythmic
N
OMe
NHHO
H2CH
Quinine (BAN) kwi·nën(8S,9R)-6¢-Methoxycinchonan-9-ol; C20H24N2O2; 130-95-0�Quinine Bisulphate 549-56-4�Quinine Dihydrochloride 60-93-5�Quinine Hydrochloride 130-89-2; ̈ LEUCOTROPIN*�Quinine Sulphate 6119-70-6Antimalarial
N
OMe
N
OH
H
H2CH
Quinisocaine (dimethisoquin) kwin·ï·sö·kän2-(3-Butyl-1-isoquinolyloxy)ethyldimethylamine; C17H24N2O; 86-80-6Local anaesthetic
N
ONMe2
Bun
Quintiofos kwin·tï·ö·fosO-Ethyl O-8-quinolyl phenylphosphonothioate; C17H16NO2PS;1776-83-6Insecticide
S
EtO P O
N
![Page 571: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/571.jpg)
4-8
Quinupristin kwin·ü·pris·tinN-[(3R,6S,7R,10S,13S,16R,20S,23S)-20-[(4-(Dimethylamino)benzyl]-3-ethyl-7,21-dimethyl-2,5,9,15,19,22-hexaoxo-10-phenyl-16-{[(3S)-quinuclidin-3-ylthio]methyl}-8-oxa-1,4,11,18,21-penta-azatricyclo[21.3.0.013,18]hexacosan-6-yl]-3-hydroxypyridine-2-carboxamide;C53H67N9O10S; 120138-50-3Antibacterial
N
S
OHN
OHN
O
O
Me
O O O
NHN HN
O
N N
H
NMe2
H Et
O
Me
O
Rabeprazole ra·be·pra·zôl2-{[4-(3-Methoxypropoxy)-3-methyl-2-pyridyl]methylsulfinyl}-1H-benzimi-dazole; C18H21N3O3S; 117976-89-3Rabeprazole Sodium 117976-90-6; PARIET
Proton pump inhibitor; treatment of peptic ulcer
N
N S
N
O OMe
O
Me
H
Racementhol ra·së·men·thol(1RS,2SR,5RS)-2-Isopropyl-5-methylcyclohexanol; C10H20O; 15356-70-4Decongestant; carminative
Me
OH
Me Me
and enantiomer
![Page 572: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/572.jpg)
4-9
�Racemethorphan(±)-3-Methoxy-9a-methylmorphinan; C18H25NO; 510-53-2
NMe
MeO
H
and enantiomer
Racemoramide ra·së·mo·ra·mïd(RS)-1-(3-Methyl-4-morpholino-2,2-diphenylbutyryl)pyrrolidine;C25H32N2O2; 545-59-5Opioid analgesic
NH Me O
N
O
and enantiomer
Racemorphan ra·së·mor·fan(±)-9a-Methylmorphinan-3-ol; C17H23NO; 297-90-5Opioid analgesic
NMe
HO
H
and enantiomer
Racephedrine ra·se·fe·drën(1RS,2SR)-2-Methylamino-1-phenylpropan-1-ol; C10H15NO; 90-81-3�Racephedrine Hydrochloride 134-71-4Sympathomimetic
CH3
H OH
H NHMe
and enantiomer
![Page 573: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/573.jpg)
4-10
Raclopride ra·klö·prïd(S)-3,5-Dichloro-N-(1-ethylpyrrolidin-2-ylmethyl)-6-methoxysalicylamide;C15H20Cl2N2O3; 84225-95-6Raclopride Tartrate 98185-20-7; A 40664Antipsychotic
N
O
EtN
HCl
Cl
OH
OMe
H
▼Rafoxanide ra·foks·a·nïd3¢-Chloro-4¢-(4-chlorophenoxy)-3,5-di-iodosalicylanilide; C19H11Cl2I2NO3;22662-39-1; ̈ FLUKANIDE; ̈ RANIZOLE*Anthelmintic
N
O
ClCl
O
I
I
OH
H
Raloxifene ra·loks·i·fën[6-Hydroxy-2-(4-hydroxyphenyl)benzo[b]thien-3-yl][4-(2-piperidinoethoxy)phenyl]methanone; C28H27NO4S; 84449-90-1; LY-156758Raloxifene Hydrochloride 82640-04-8; EVISTA
Selective oestrogen receptor modulator; prevention of osteoporosis
S
ON
OH
O
HO
Raltitrexed ral·ti·treks·edN-{5-[3,4-Dihydro-2-methyl-4-oxoquinazolin-6-ylmethyl(methyl)amino]-2-thenoyl}-L-glutamic acid; C21H22N4O6S; 112887-68-0; TOMUDEX
Thymidylate synthase inhibitor; antineoplastic
SN
N
N
N
OMeMe
O
COOH
COOH
H
H
H
![Page 574: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/574.jpg)
4-11
Ramatroban ra·ma·trö·ban(R)-3-[3-(4-Fluorophenylsulfonylamino)-1,2,3,4-tetrahydrocarbazol-9-yl]propionic acid; C21H21FN2O4S; 116649-85-5; BAY u 3405; EN 137774Thromboxane endoperoxide receptor antagonist; treatment of cardiovascular andairway diseases
NS
COOH
N
F
H
O O
H
�Ramipril ra·mi·pril(1) (2S,3aS,6aS)-1-{N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl}-perhydrocyclopenta[b]pyrrole-2-carboxylic acid; (2) (1S,3S,5S)-2-{N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl}-2-azabicyclo[3.3.0]octane-3-carboxylic acid; C23H32N2O5; 87333-19-5; TRITACE
Angiotensin-converting enzyme inhibitor; antihypertensive
H
H
COOHHN
O
MeHH
EtOOC
Ranitidine ra·ni·ti·dënDimethyl{5-[2-(1-methylamino-2-nitrovinylamino)ethylthiomethyl]-furfuryl}amine; C13H22N4O3S; 66357-35-5; AH 19065Ranitidine Hydrochloride ZANTAC
Histamine H2-receptor antagonist
OMe2N S
HN
NO2
NHMe
Ranitidine Bismuth Citrate (BAN)Bismuth(III) citrate¾ (E)-N-{2-[5-(dimethylaminomethyl)furfurylthio]-ethyl}-N´-methyl-2-nitrovinylidenediamine (ranitidine); ranitidinebismutrex; C13H22N4O3S·Bi·C6H5O7; 128345-62-0; PYLORID
Histamine H2-receptor antagonist
![Page 575: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/575.jpg)
4-12
Rapacuronium Bromide ra·pa·kûr·rö·në·um1-(3a-Acetoxy-2b-piperidino-17b-propionyloxy-5a-androstan-16b-yl)-1-allylpiperidinium bromide; C37H61BrN2O4; 156137-99-4; Org 9487Neuromuscular blocker
NN
AcOH
Me O
H2C
H
H
CH3
O
H H
HMe+
HBr
_
Rasburicase ras·bûr·ri·käsA recombinant urate oxidase obtained from Aspergillus flavus, expressed inyeast strain Saccharomyces cerevisiae; C1523H2383N427O462S7; SR 29142
Treatment and prophylaxis of hyperuricaemia
rasburicase has the following amino acid sequence:
SAVKAARYGK DNVRVYKVHK DEKTGVQTVY
EMTVCVLLEG EIETSYTKAD NSVIVATDSI
KNTIYITAKQ NPVTPPELFG SILGTHFIEK
YNHIHAAHVN IVCHRWTRMD IDGKPHPHSF
IRDSEEKRNV QVDVVEGKGI DIKSSLSGLT
VLKSTNSQFW GFLRDEYTTL KETWDRILST
DVDATWQWKN FSGLQEVRSH VPKFDATWAT
AREVTLKTFA EDNSASVQAT MYKMAEQILA
RQQLIETVEY SLPNKHYFEI DLSWHKGLQN
TGKNAEVFAP QSDPNGLIKC TVGRSSLKSK
L
Ac
�Razoxane ra·zoks·än4,4¢-(1-Methylethylene)bis(piperazine-2,6-dione); C11H16N4O4; 21416-87-1Cytotoxic
HN
NN
NHH Me
O
OO
Oand enantiomer
![Page 576: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/576.jpg)
4-13
Reboxetine re·boks·e·tën(±)-(2RS)-2-[(aRS)-a-(2-Ethoxyphenoxy)benzyl]morpholine; C19H23NO3;71620-89-8; FCE-20124Reboxetine Mesilate EDRONAX
Alpha2-adrenergic receptor antagonist; antidepressant
O
NH
O
OEt
H H
and enantiomer
Recainam re·kä·nam1-[3-(Isopropylamino)propyl]-3-(2,6-xylyl)urea; C15H25N3O; 74738-24-2; Wy42362Recainam Hydrochloride 74752-07-1Recainam Tosilate 74752-08-2Antiarrhythmic
N N NHPr iMe
MeO
H H
Remifentanil re·mi·fen·ta·nilMethyl 1-(2-methoxycarbonylethyl)-4-(N-phenylpropionamido)piperidine-4-carboxylate; C20H28N2O5; 132875-61-7; ULTIVA
Remifentanil Hydrochloride 132539-07-2; GI 87084BOpioid analgesic; anaesthestic
N
NCH3
O
COOMeMeOOC
�Remoxipride re·moks·i·prïd(S)-3-Bromo-N-(1-ethylpyrrolidin-2-ylmethyl)-2,6-dimethoxybenzamide;C16H23BrN2O3; 80125-14-0; A 33547Antipsychotic
N
O
EtN
H
Br
OMe
OMe
H
![Page 577: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/577.jpg)
4-14
Renzapride ren·za·prïd(±)-endo-4-Amino-N-(1-azabicyclo[3.3.1]non-4-yl)-5-chloro-o-anisamide;C16H22ClN3O2; 11727-80-7; 88721-77-1 (racemate)Renzapride Hydrochloride BRL 24924AIncrease of gastro-intestinal motility
and enantiomer
NH2MeO
Cl
O
HN
N
Repaglinide re·pa·gli·nïde(S)-2-Ethoxy-4-{[1-(o-piperidinophenyl)-3-methylbutyl]carbamoylmethyl}benzoic acid; C27H36N2O4; 135062-92-1;NOVONORM
Hypoglycaemic
N
N
OEt
COOHOBu i H
H
Reproterol re·prö·te·rol7-[3-(b,3,5-Trihydroxyphenethylamino)propyl]theophylline; C18H23N5O5;54063-54-6Reproterol Hydrochloride 13055-82-8; BRONCHODIL
Beta-adrenoceptor agonist
and enantiomer
OHH
OH
OH
O
O
Me
Me
HN
N
NN
N
![Page 578: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/578.jpg)
4-15
Rescinnamine re·si·na·mënMethyl-O-(3,4,5-trimethoxycinnamoyl)reserpate; C35H42N2O9;24815-24-5Antipsychotic; antihypertensive
H
OMe
OMe
OMe
H
H
HMeO
MeOOC
OMe
O
O
NN
H
H
�Reserpine re·ser·pënAn alkaloid obtained from Rauwolfia serpentina Benth; (1) methyl 11,17a-dimethoxy-18b-(3,4,5-trimethoxybenzoyloxy)-3b,20a-yohimbane-16b-carboxylate; (2) methyl O-(3,4,5-trimethoxybenzoyl)reserpate; C33H40N2O9;50-55-5Antipsychotic; antihypertensive
OMe
OMe
OMe
H
H
HMeO
MeOOC
OMe
O
O
NN
H
H
![Page 579: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/579.jpg)
4-16
Reteplase re·te·pläz173-L-Serine-174-L-tyrosine-175-L-glutamine-173— 527-plasminogenactivator (human tissue-type); C1736H2653N499O522S22; 133652-38-7Thrombolyticreteplase has the following amino acid sequence (cf alteplase):
SYQNSDC
YFGNGSAYRG THSLTESGAS CLPWNSMILI
GKVYTAQNPS AQALGLGKHN YCRNPDGDAK
PWCHVLKNRR LTWEYCDVPS CSTCGLRQYS
QPQFR
IKGGLFADIA SHPWQAAIFA KHRRSPGERF
LCGGILISSC WILSAAHCFQ ERFPPHHLTV
ILGRTYRVVP GEEEQKFEVE KYIVHKEFDD
DTYDNDIALL QLKSDSSRCA QESSVVRTVC
LPPADLQLPD WTECELSGYG KHEALSPFYS
ERLKEAHVRL YPSSRCTSQH LLNRTVTDNM
LCAGDTRSGG PQANLHDACQ GDSGGPLVCL
NDGRMTLVGI ISWGLGCGQK DVPGVYTKVT
NYLDWIRDNM RP
Retinol re·ti·nol(1) 15-Apo-b-caroten-15-ol; (2) all-trans-3,7-dimethyl-9-(2,6,6-trimethylcyclohex-1-enyl)nona-2,4,6,8-tetraen-1-ol; vitamin A alcohol;C20H30O;68-26-8; RO-A-VIT
Vitamin A component
Me
Me
Me Me Me
OH
![Page 580: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/580.jpg)
4-17
Revatropate re·va·trö·pät(R)-3-Quinuclidinyl (2S)-2-hydroxymethyl-4-(R)-methylsulfinyl-2-phenylbutyrate; C19H27NO4S; UK-112,166Revatropate Hydrobromide UK-112,166-04Antimuscarinic; bronchodilator
N
H
OOH
Me
S
O
O
Reviparin Sodium re·vi·pa·rin sö·dë·umSodium salt of a low molecular weight heparin that is obtained by nitrousacid depolymerisation of heparin from porcine intestinal mucosa; themajority of the components have a 2-O-sulfo-a-L-idopyranosuronic acidstructure at the non-reducing end and a 6-O-sulfo-2,5-anhydro-D-mannitolstructure at the reducing end of their chain; the weight-average molecularweight ranges between 3150 and 5150, with a characteristic value of about4250; the degree of sulfation is about 2.1 per disaccharide unit.Anticoagulant
Revospirone re·vö·spï·rön2-{3-[4-(Pyrimidin-2-yl)piperazin-1-yl]propyl}-1,2-benzothiazol-3(2H)-one1,1-dioxide; C18H21N5O3S; 95847-87-3; Bay Vq 7813Tranquilliser (veterinary)
N N
N
N
NO
SOO
�Riboflavin (riboflavine) rï·bö·flä·vin7,8-Dimethyl-10-(1¢-D-ribityl)isoalloxazine; C17H20N4O6; 83-88-5; compo-nent in many proprietary preparations�Riboflavin Sodium Phosphate 130-40-5Vitamin
N
N
N
N
OH
OHOH
OH
OO
Me
Me
H
![Page 581: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/581.jpg)
4-18
Ribostamycin rï·bö·sta·mï·sin2-Deoxy-4-O-(2,6-diamino-2,6-dideoxy-a-D-glucopyranosyl)-5-O-(b-D-ribofuranosyl)-D-streptamine; C17H34N4O10; 25546-65-0Antibiotic
O
NH2
HO
OH
H2NO
NH2
NH2
OH
O
OHOH
OHO
Ricasetron ri·ka·se·tron2,3-Dihydro-3,3-dimethyl-N-[(3r)-8-methyl-8-azabicyclo[3.2.1]octan-3-yl]indole-1-carboxamide; C19H27N3O; 117086-68-7Ricasetron Hydrochloride 140865-88-9; BRL 46670-AAnxiolytic; 5HT3-receptor antagonist
N
O NH
Me Me
NMe
Ridogrel rï·dö·grel(E)-5-[a-(3-Pyridyl)-3-trifluoromethylbenzylideneamino-oxy]pentanoicacid; C18H17F3N2O3; 110140-89-1; R 68070Thromboxane synthetase inhibitor
OCOOH
N
N
CF3
![Page 582: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/582.jpg)
4-19
Rifabutin ri·fa·bü·tin(12E,22E,24Z)(9S,14S,15R,16S,17R,18R,19R,20S,21S)-3,5,9,10-Tetrahydro-6,18,20-trihydroxy-1¢-isobutyl-14-methoxy-7,9,15,17,19,21,25-heptamethyl-5,10,26-trioxospiro[9,4-(epoxypentadeca[1,11,13]trienimino)-2H-furo[2¢,3¢:7,8]-naphtho[1,2-d]imidazole-2,4¢-piperidin]-16-yl acetate; C46H62N4O11; 72559-06-9;MYCOBUTIN
Antibiotic
O
OMe
OAc
OHMeMe
Me
HNMe
Me
O
O
Me
MeOH
HO
O
HNN
NBun
O
Rifamide ri·fa·mïdRifamycin B N,N-diethylamide; C43H58N2O13; 2750-76-7Antibiotic
O
OMe
OAc
OHMeMe
Me
HNMe
Me
OH
O
O
Me
MeOH
HO
O
OO
Et2N
![Page 583: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/583.jpg)
4-20
�Rifampicin ri·fam·pi·sin(1) (12Z,14E,24E)-(2S,16S,17S,18R,19R,20R,21S, 22R,23S)-1,2-Dihydro-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12, 16,18,20,22-heptamethyl-8-(4-methylpiperazin-1-yliminomethyl)-1,11-dioxo-2,7-(epoxypentadeca-1,11,13-trienoimino)naphtho[2,1-b]furan-21-yl acetate;(2) 3-(4-methylpiperazin-1-yliminomethyl)rifamycin SV; rifampin (USAN);C43H58N4O12; 13292-46-1; RIFADIN; RIFATER*; RIFINAH*; RIMACTANE; RIMACTAZID*Antitubercular
O
OMe
OAc
OHMeMe
Me
HN
H OH
Me
Me
N
OH
OO
Me
Me
NN
MeOH
HO
O
Rifamycin ri·fa·mï·sinAn ansamycin antibiotic produced by certain strains of Streptomycesmediterranei; (12Z,14E,24E)-(2S,16S,17S,18R,19R,20R, 21S,22R,23S)-1,2-Dihydro-5,6,9,17,19-pentahydroxy-23-methoxy-2,4,12,16,18,20,22-heptamethyl-1,11-dioxo-2,7-(epoxypentadeca-1,11,13-trienoimino)-naphtho[2,1-b]furan-21-yl acetate; rifamycin SV; C37H47NO12;6998-60-3�Rifamycin Sodium 14897-39-3Antibiotic
O
OMe
OAc
OHMeMe
Me
HNMe
Me
OH
OO
Me
MeOH
HO
OOH
![Page 584: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/584.jpg)
4-21
Rifapentine ri·fa·pen·tën(4Z,6E,16E)-(8S,9S,10R,11R,12R,13S,14R,15S,19S)-26-[N-(4-Cyclo-pentylpiperazin-1-yl)formimidoyl]-9,11,23,25,27-pentahydroxy-15-methoxy-4,8,10,12,14,19,22-heptamethyl-3,30-dioxo-18,20-dioxa-2-azatetracyclo[17.6.5.021,29·024,28]triaconta-1(25),4,6,16,21(29),22,24(28),26-octaen-13-yl acetate; C47H64N4O12; 61379-65-5; L 11473;DL-473-IT; MDL-473Antibiotic
N
NN
OHO
HO
OHMe
Me
OO
OH
Me
MeHN
Me
Me MeOH
OAc
OMe
O
Riluzole ri·lü·zôl6-Trifluoromethoxy-1,3-benzothiazol-2-ylamine; C8H5F3N2OS; 1744-22-5;RILUTEK
Glutamate antagonist; treatment of amyotrophic lateral sclerosis
N
S NH2F3CO
Rimantadine ri·man·ta·dën(RS)-1-(Adamantan-1-yl)ethylamine; C12H21N; 13392-28-4Rimantadine Hydrochloride 1501-84-4Antiviral
and enantiomer
NH2H
Me
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Rimexolone ri·meks·o·lön11b-Hydroxy-16a,17a-dimethyl-17b-propionylandrosta-1,4-dien-3-one;C24H34O3; 49697-38-3Anti-inflammatory
O
Me
H
H
H
HOMe
MeMe
EtO
Rimiterol ri·mi·te·rolerythro-3,4-Dihydroxy-a-(2-piperidyl)benzyl alcohol; C12H17NO3;32953-89-2Rimiterol Hydrobromide 31842-61-2; PULMADIL
Beta-adrenoceptor agonist
HO
HO
H OH
HNH
and enantiomer
Rioprostil rï·ö·pros·til(E)-(2R,3R,4R)-4-Hydroxy-2-(7-hydroxyheptyl)-3-(4-hydroxy-4-methyloct-1-enyl)cyclopentanone; C21H38O4; 77287-05-9; BAY o 6893; TR 4698; ORF15927Prostanoid gastric antisecretory
H
HHO
CH3
O
OH
OHMe
Risedronic acid rï·se·dro·nik1-Hydroxy-2-(3-pyridyl)ethane-1,1-diylbis(phosphonic acid); C7H11NO7P2;105462-24-6Risedronate Sodium (monosodium)115436-72-1; NE-58095Bisphosphonate; treatment of osteoporosis
N
P
O
OHOH
P
O
HO
OH
HO
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4-23
Risperidone ris·per·ri·dön3-{2-[4-(6-Fluoro-1,2-benzoxazol-3-yl)piperidino]ethyl}-6,7,8,9-tetrahydro-2-methylpyrido[1,2-a]pyrimidin-4-one; C23H27FN4O2; 106266-06-2; RISPERIDAL
Antipsychotic
N
N
N
ON
O
F
Me
Ristianol ris·tï·a·nol2-(4-Pyridylmethylthio)ethanol; C8H11NOS; 78092-65-6Ristianol Phosphate 78092-66-7; CP-48,867-09Immunoregulant
N
SOH
Ristocetin ris·tö·së·tinAntimicrobial glycopeptides produced by Nocardia lurida; 1404-55-3Antibiotic
Ritanserin ri·tan·ser·rin6-{2-[4-(4,4¢-Difluorobenzhydrylidene)piperidino]ethyl}-7-methyl-[1,3]thiazolo[3,2-a]pyrimidin-5-one; C27H25F2N3OS; 87051-43-2Serotonin receptor antagonist
NN
N S
F
F
O
Me
Ritodrine rï·tö·drën(±)-erythro-1-(4-Hydroxyphenyl)-2-(4-hydroxyphenethylamino)propan-1-ol; C17H21NO3; 26652-09-5�Ritodrine Hydrochloride 23239-51-2; YUTOPAR
Beta-adrenoceptor agonist
HO
NH OH
H MeOH
H
and enantiomer
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Ritonavir rï·to·na·veerN1-[(1S,3S,4S)-1-Benzyl-3-hydroxy-5-phenyl-4-(1,3-thiazol-5-ylmethoxycarbonylamino)pentyl]-N2-{[(2-isopropyl-1,3-thiazol-4-yl)methyl](methyl)carbamoyl}-L-valinamide; C37H48N6O5S2; 155213-67-5;NORVIR
HIV-protease inhibitor; antiviral
N NN
N ON
S
Me
Me Me
Me Me
O
OH
H OH
H
HN
S
O
H H
H
Rituximab ri·tuks·i·mabImmunoglobulin G 1, human/mouse monoclonal antibody IDEC-C2B8directed against the human antigen CD20 consisting of murine variabledomains with human k light chains and g1 heavy chains; anti-CD20 mab;MABTHERA
Antineoplastic; treatment of lymphoma
Rivastigmine ri·va·stig·mën3-[(S)-1-(Dimethylamino)ethyl]phenyl ethyl(methyl)carbamate; C14H22N2O2;123441-03-2
Treatment of Alzheimer’s disease
H3C N ONMe2
MeH
O
Me
Rizatriptan rï·za·trip·tanDimethyl{2-[5-(1H-1,2,4-triazol-1-ylmethyl)indol-3-yl]ethyl}amine;C15H19N5; 144034-80-0; MK 462Rizatriptan Benzoate MAXALT
Serotonin receptor agonist; treatment of migraine
NN
N N
NMe2
H
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Robenidine rö·be·ni·dën1,3-Bis(4-chlorobenzylideneamino)guanidine; C15H13Cl2N5; 25875-51-8;¨CYCOSTAT 66Antiprotozoan
N
Cl
N N
NH
H N
Cl
N
Rocuronium Bromide ro·k ûr·rö·në·um1-(17b-Acetoxy-3a-hydroxy-2b-morpholino-5a-androstan-16b-yl)-1-allylpyrrolidinium bromide; C32H53BrN2O4; 119302-91-9; ESMERON
Neuromuscular blocker
N
ON
HO
Me
H
H
H
H
Me OAc
CH2
+ Br_
Rofecoxib rö·fë·koks·ib4-(4-Mesylphenyl)-3-phenylfuran-2(5H)-one; C17H14O4S; 162011-90-7; VIOXX
Cyclo-oxygenase-2 inhibitor; non-steroidal anti-inflammatoryOO
SCH3
O O
Rogletimide rö·gle·ti·mïd(RS)-2-Ethyl-2-(4-pyridyl)glutarimide; C12H14N2O2; 121840-95-7Inhibitor of adrenal corticosteroid synthesis
NH
N
Et
O
O
and enantiomer
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Rolgamidine rol·ga·mi·dëntrans-N-Diaminomethylene-2-(2,5-dimethyl-3-pyrrolin-1-yl)acetamide;C9H16N4O; 66608-04-6Rolgamidine Hydrochloride 65767-06-8 (2HCl); Wy 25021Antidiarrhoeal
N
N NH2
MeMe
O NH2
and enantiomer
Rolicyprine (rolicypram) rö·li·sï·prën(+)-L-5-Oxo-N-(trans-2-phenylcyclopropyl)pyrrolidine-2-carboxamide;C14H16N2O2; 2829-19-8Antidepressant
O
HO
NH
HN
Rolitetracycline rö·li·te·tra·sï·klënN 2-(Pyrrolidin-1-ylmethyl)tetracycline; C27H33N3O8; 751-97-3Rolitetracycline Nitrate 7681-32-5Antibacterial
OH O HO O
OH
NMe2HH
MeHO
OH
N N
O
H
Rolziracetam rol·zi·ra·se·tamPerhydropyrrolizine-3,5-dione; C7H9NO2; 18356-28-0; CI-911Treatment of impaired mental function in the elderly
N
O O
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Romazarit ro·ma·za·rit2-(2-p-Chlorophenyl-4-methyl-1,3-oxazol-5-ylmethoxy)-2-methylpropionicacid; C15H16ClNO4; 109543-76-2; Ro-31-3948/000Romazarit Sodium 109544-09-4; Ro 31-3948/002Anti-inflammatory
N
OMeMe
COOHO
Me
Cl
Romifidine ro·mi·fi·dën2-Bromo-6-fluoro-N-(1-imidazolin-2-yl)aniline; C9H9BrFN3;65896-16-4Romifidine Hydrochloride 65896-14-2; ̈ SEDIVET
Alpha2-adrenoceptor agonist
N
NN
Br
F
H H
▼Ronidazole ro·nïd·a·zôl(1-Methyl-5-nitroimidazol-2-yl)methyl carbamate; C6H8N4O4;7681-76-7; ̈ TRICHO PLUS
Antiprotozoan
N
NO2N
Me
O NH2
O
Ropinirole rö·pi·ni·rôl4-[2-(Dipropylamino)ethyl]indolin-2-one; C16H24N2O; 91374-21-9;Ropinirole Hydrochloride 91374-20-8; REQUIP
D2-Dopamine receptor agonist
NHPrn2N
O
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Ropivacaine rö·pi·va·kän(S)-2¢,6¢-Dimethyl-1-propylpiperidine-2-carboxanilide; C17H26N2O;84057-95-4Ropivacaine Hydrochloride 98717-15-8 (anhydrous), 132112-35-7 (monohy-drate); AL 281; NAROP
Local anaesthetic
NN
OMe
MeH
Prn
H
Rosaramicin rös·a·ra·mï·sin(E)-3-Ethyl-10-(formylmethyl)-7-hydroxy-2,8,12,16-tetramethyl-9-(3,4,6-trideoxy-3-dimethylamino-b-D-xylo-hexopyranosyloxy)-4,17-dioxa-bicyclo[14.1.0]heptadec-14-ene-5,13-dione; C31H51NO9;35834-26-5; Sch 14947Antibiotic
O
Me
OH
NMe2
Me
O
O
Et
O
OH
Me
Me
O
Me
O
H
CHO
Rosiglitazone rö·si·gli·ta·zön{(RS)-5-(4-{2-[Methyl(2-pyridyl)amino]ethoxy}benzyl)-1,3-thiazolidine-2,4-dione; C18H19N3O3S; 122320-73-4Oral hypoglycaemic
N
NO
SNH
Me
O
OH
and enantiomer
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Rosoxacin/Acrosoxacin rö·soks·a·sin/ a·krö·soks·a·sin1-Ethyl-1,4-dihydro-4-oxo-7-(4-pyridyl)quinoline-3-carboxylic acid;C17H14N2O3; 40034-42-2; ERADACIN
Antibacterial
N
N
O
COOH
Et
Rosuvastatin ro·sü·va·sta·tin(E)-(3R,5S)-7-{4-(4-Fluorophenyl)-6-isopropyl-2-[methyl(methylsulfonyl)amino]pyrimidin-5-yl}-3,5-dihydroxyhept-6-enoicacid; C22H28FN3O6S; ZD4522Rosuvastatin Calcium 147098-20-2; S-4522HMG Co-A reductase inhibitor; hypolipidaemic
N
N
F
NMeO2S
Me
Pr i
COOH
HHHO OH
Roxarsone roks·ar·sön4-Hydroxy-3-nitrophenylarsonic acid; C6H6AsNO6; 121-19-7Antiprotozoan; growth promoter
AsO
OH
OH
NO2
OH
Roxatidine roks·a·ti·dënN-[3-(a-Piperidino-m-tolyloxy)propyl]glycolamide; C17H26N2O3;97900-88-4; HOE 062Histamine H2-receptor antagonist
NO N
OH
O
H
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Roxatidine Acetate roks·a·ti·dën a·së·tät3-(a-Piperidino-m-tolyloxy)propylcarbamoylmethyl acetate; C19H28N2O4;78628-28-1Roxatidine Acetate Hydrochloride 93793-83-0 HOE 760; TZU 0460Histamine H2-receptor antagonist
NO N
O
O
CH3
OH
Rufinamide rü·fin·a·mïd1-(2,6-Difluorobenzyl)-1H-1,2,3-triazole-4-carboxamide; C10H8F2N4O;106308-44-5Anticonvulsant
F N
N
N
F
CONH2
Rufloxacin roo·floks·a·sin9-Fluoro-2,3-dihydro-10-(4-methylpiperazin-1-yl)-7-oxo-7H-pyrido[1,2,3-de]-1,4-benzothiazine-6-carboxylic acid; C17H18FN3O3S; 101363-10-4; MF934Antibacterial
N
S
N
NMe
F COOH
O
�RufocromomycinA benzoquinonoid antibiotic produced by Streptomyces rufochromogenus or S.flocculus; 5-amino-6-(7-amino-5,8-dihydro-6-methoxy-5,8-dioxo-2-quinolyl)-4-(2-hydroxy-3,4-dimethoxyphenyl)-3-methylpicolinic acid; streptonigrin(USAN); C25H22N4O8; 3930-19-6
N
N
NH2
COOH
MeOH
OMe
OMe
O
O
H2N
MeO
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Rutoside roo·tö·sïd2-(3,4-Dihydroxyphenyl)-5,7-dihydroxy-4-oxo-4H-chromen-3-yl 6-O-(a-L-rhamnosyl)-b-D-glucoside; rutin; C27H30O16; 153-18-4; PHARMATON*; VIVIOPTAL*Nutritional supplement
OH
HO
OH
OHO
OO
OH
OH
OH
O
OO
Me
OHOH
HO
Sabcomeline sab·kö·me·lën(Z)-[(R)-Quinuclidin-3-yl](methoxyimino)acetonitrile; C10H15N3O;159912-53-5; SB-202026Sabcomeline Hydrochloride SB-202026-AMuscarinic M1-receptor partial agonist; treatment of Alzheimer’s disease
NCN
NOMe
H
Sabeluzole sa·be·lu·zôl1-{4-[1,3-Benzothiazol-2-yl(methyl)amino]piperidino}-3-(4-fluoro-phenoxy)propan-2-ol; C22H26FN3O2S; 104153-38-0; R58735Anticonvulsant
F
O NH OH
N
N
S
Me
and enantiomer
Salazosulfadimidine (salazosulphadimidine) sa·lä·zö·sul·fa·dï·mi·dën4¢-(4,6-Dimethylpyrimidin-2-ylsulfamoyl)-4-hydroxyazobenzene-3-carboxy-lic acid; C19H17N5O5S; 2315-08-4Sulphonamide
N
N
N
Me
Me
N N
OH
COOH
SOO
H
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�Salbutamol sal·bü·ta·mol1-(4-Hydroxy-3-hydroxymethylphenyl)-2-(tert-butylamino)ethanol;albuterol (USAN); C13H21NO3; 18559-94-9; AEROCROM*; ASMAVEN; MAXIVENT;SALAMOL; VENTIDE*; VENTOLIN INHALER; VENTOLIN ROTACAPS
�Salbutamol Sulphate 51022-70-9; AEROLIN; AIROMIR; ASMAVEN; COBUTALIN;COMBIVENT*; SALBULIN; VENTIDE*; VENTODISKS; VENTOLIN; VOLMAX
Beta-adrenoceptor agonist
HO
NHBu tH OH
HO
and enantiomer
Salcatonin see Calcitonin (Salmon)
Salicylamide sa·li·sï·la·mïd2-Hydroxybenzamide; C7H7NO2; 65-45-2; INTRALGIN*Analgesic; antipyretic
CONH2
OH
Salinazid sa·li·na·zid2¢-Salicylideneisonicotinohydrazide; C13H11N3O2; 495-84-1Antitubercular
OH
NN
O
NH
Salinomycin sa·li·nö·mï·sin(2R)-2-{(2R,5S,6R)-6-[(1S,2S,3S,5R)-5-{2S,5S,7R,9S,10S,12R,15R)-2-[(2R,5R,6S)-5-Ethyltetrahydro-5-hydroxy-6-methylpyran-2-yl]-15-hydroxy-2,10,12-trimethyl-1,6,8-trioxadispiro[4.1.5.3]pentadec-13-en-9-yl}-2-hydroxy-1,3-dimethyl-4-oxoheptyl]tetrahydro-5-methylpyran-2-yl}butyricacid; C42H70O11; 53003-10-4; ̈ KOKCISAN; ̈ SACOX; ̈ SALGAIN
Anticoccidial (veterinary)
O
O
OO O
O
OH
OH
Et
MeMe
MeMe
HEt
OH
Me
Me
COOH
Et
H
H
H
Me
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Salmefamol sal·me·fa·mol1-(4-Hydroxy-3-hydroxymethylphenyl)-2-(4-methoxy-a-methylphenethyl-amino)ethanol; C19H25NO4; 18910-65-1Beta-adrenoceptor agonist
N
HO
HO
OMe
OH
Me
H
* *
mixture of stereoisomers
Salmeterol sal·me·te·rol(RS)-5-{1-Hydroxy-2-[6-(4-phenylbutoxy)hexylamino]ethyl}salicyl alcohol;C25H37NO4; 89365-50-4Salmeterol Xinafoate 94749-08-3; SEREVENT; seretide*Beta-adrenoceptor agonist
HN
O
HO
HO
OHH
and enantiomer
Sampatrilat sam·pa·tri·latN-{1-[(S)-2-Carboxy-3-(N2-mesyl-L-lysylamino)propyl]cyclopentylcarbonyl}-L-tyrosine; C26H40N4O9S;129981-36-8; UK-81,252Angiotensin-converting enzyme inhibitor; neutral endopeptidase (atriopeptidase)inhibitor; antihypertensive
NH
HO
N
H2N
H NHSO2Me
H
COOHO
O
COOH
H
H
�Salsalate sal·sa·lätO-(2-Hydroxybenzoyl)salicylic acid; C14H10O5; 552-94-3Analgesic; anti-inflammatory
O
COOH
O OH
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Sanfetrinem san·fe·tri·nem(1S,5S,8aS,8bR)-1,2,5,6,7,8,8a,8b-Octahydro-1-[(R)-1-hydroxyethyl]-5-methoxy-2-oxoazeto[2,1-a]isoindole-4-carboxylate; C14H19NO5;141611-76-9; GV 104326X;Sanfetrinem Cilexetil; 141646-08-4; GV 118819XSanfetrinem Sodium 141611-76-9; GV 104326BAntibacterial
N
OMe
COOHO
H3C
H HHHO H
Saperconazole sa·per·ko·na·zôl(±)-2-sec-Butyl-4-[4-(4-{4-[(2RS,4SR)-2-(2,4-difluorophenyl)-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-4-ylmethoxy]phenyl}piperazin-1-yl)-phenyl]-2,4-dihydro-1,2,4-triazol-3-one; C35H38F2N8O4; 110588-57-3;R 66905Antifungal
N
N
N
OO
N
N
NF
FO
N
N
H
H3CH Me O
*
mixture of 4 isomers
Saprisartan sa·pri·sar·tan1-{3-Bromo-2-[2-trifluoromethylsulfonylamino)phenyl]benzo[b]furan-5-ylmethyl}-4-cyclopropyl-2-ethyl-1H-imidazole-5-carboxamide;C25H21BrF3N4O4S; GR 138950XSaprisartan Potassium 146623-69-0; GR 138950CAngiotensin II antagonist; antihypertensive
O N
Br
NN
CONH2
Et
CF3S
OO
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Saquinavir sa·kwi·na·veerN1-{(1S,2R)-1-Benzyl-3-[(3S,4aS,8aS)-3-(tert-butylcarbamoyl)perhydro-isoquinolin-2-yl]-2-hydroxypropyl}-N2-(2-quinolylcarbonyl)-L-aspartamide;C38H50N6O5; 127779-20-8; Ro 31-8959Saquinavir Mesylate 149845-06-7; INVIRASE
HIV proteinase inhibitor; antiviral
N
NN
O
O
CONH2
N
CONHBut
H
H
OHHH
H H
H
H
Sarafloxacin sa·ra·floks·a·sin6-Fluoro-1-(4-fluorophenyl)-1,4-dihydro-4-oxo-7-piperazin-1-ylquinoline-3-carboxylic acid; C20H17F2N3O3; 98105-99-8; A-57135Sarafloxacin Hydrochloride 91296-87-6; A-56620Antibacterial
HN
N N
F
F
COOH
O
Saralasin sa·ra·lä·sin[1-(N-Methylglycine),5-valine,8-alanine]angiotensin; C42H65N13O10; 34273-10-4Saralasin Acetate 39698-78-7Diagnosis of renin-dependent hypertension
Sar-Arg-Val-Tyr-Val-His-Pro-Ala
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Sargramostim sar·gra·mos·timRecombinant granulocyte macrophage colony stimulating factor; aglycosylated recombinant analogue expressed by Saccharomyces cerevisiae;GM-CSF; C639H993N168O196S8 (ionised, non-glycosylated form);C639H999N168O196S8 (non-ionised, non-glycosylated form);83869-56-1; BI-61·012ImmunostimulantFor labelling purposes the following three-letter code, to indicate themethod of production, is approved:
(rys) produced by fermentation using Saccharomyces cerevisiae containing arecombinant plasmid
Sargramostim has the following amino acid sequence:
APARSPSPST QPWEHVNAIQ EALRLLNLSR
DTAAEMNETV EVISEMFDLQ EPTCLQTRLE
LYKQGLRGSL TKLKGPLTMM ASHYKQHCPP
TPETSCATQI ITFESFKENL KDFLLVIPFD
CWEPVQE
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Saruplase sa·roo·pläsProurokinase (enzyme-activating) (human clone pA3/pD2/pF1 proteinmoiety), non-glycosylated; C2031H3121N585O601S31; 99149-95-8FibrinolyticSaruplase has the following amino acid sequence (Cys—Cys bridging notshown):
SNELHQVPSN CDCLNGGTCV SNKYFSNIHW
CNCPKKFGGQ HCEIDKSKTC YEGNGHFYRG
KASTDTMGRP CLPWNSATVL QQTYHAHRSD
ALQLGLGKHN YCRNPDNRRR PWCYVQVGLK
PLVQECMVHD CADGKKPSSP PEELKFQCGQ
KTLRPRFKII GGEFTTIENQ PWFAAIYRRH
RGGSVTYVCG GSLISPCWVI SATHCFIDYP
KKEDYIVYLG RSRLNSNTQG EMKFEVENLI
LHKDYSADTL AHHNDIALLK IRSKEGRCAQ
PSRTIQTICL PSMYNDPQFG TSCEITGFGK
ENSTDYLYPE QLKMTVVKLI SHRECQQPHY
YGSEVTTKML CAADPQWKTD SCQGDSGGPL
VCSLQGRMTL TGIVSWGRGC ALKDKPGVYT
RVSHFLPWIR SHTKEENGLA L
Satumomab sa·tü·mö·mabMouse IgG 1 cell monoclonal immunoglobulinIndium[111In] Satumomab Pendetide ONCOSCINT
Colorectal carcinoma imaging agent
Secalciferol se·kal·si·fe·rol(1) (5Z,7E)-(3S,24R)-9,10-Secocholesta-5,7,10(19)-triene-3, 24,25-triol;(2) (24R)-24,25-dihydroxycholecalciferol; C27H44O3; 55721-11-4Treatment of vitamin D deficiency
Me
Me
OH
H2C
H
HMe
MeH H OH
HO
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�Secbutobarbital (secbutobarbitone)5-sec-Butyl-5-ethylbarbituric acid; butabarbitone; butabarbital (USAN);C10H15N2NaO3; 125-40-6
NH
N OO
O
H3CMe H Et
H
and enantiomer
Secnidazole sek·nï·da·zôl1-(2-Methyl-5-nitroimidazol-1-yl)propan-2-ol; C7H11N3O3; 3366-95-8; 14539RPAntiprotozoan
N
NO2N Me
CH3
H OH
and enantiomer
�SecretinA polypeptide hormone, obtained from duodenal mucosa, that activatespancreatic secretion and lowers the blood sugar level; 1393-25-5
Seganserin se·gan·ser·rin3-{2-[4-(4,4¢-Difluorobenzhydrylidene)piperidino]ethyl}-2-methyl-pyrido[1,2-a]pyrimidin-4-one; C29H27F2N3O; 87729-89-3Seganserin Hydrochloride 97939-66-1; R564135HT2-Serotonin receptor antagonist
NN
N
F
F
O
Me
Selegiline se·lej·i·lën(R)-Methyl(a-methylphenethyl)prop-2-ynylamine; C13H17N; 14611-51-9Selegiline Hydrochloride 14611-52-0; ELDEPRYL; ZELEPAR
Monoamine oxidase inhibitor
N
H Me
MeCH
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Semduramicin sem·dûr·ra·mï·sin(2R,3S,4S,5R,6S)-Tetrahydro-2,4-dihydroxy-6-{(R)-1-[(2S,5R,7S,8R,9S)-9-hydroxy-2,8-dimethyl-2-{(2S,2¢R,3¢S,5R,5¢R)-octahydro-2-methyl-5¢-[(2S,3S,5R,6S)-tetrahydro-6-hydroxy-3,5,6-trimethyl-2H-pyran-2-yl]-3¢-[(2S,5S,6R)-tetrahydro-5-methoxy-6-methyl-2H-pyran-2-yloxy]-2,2¢-bifuran-5-yl}-1,6-dioxaspiro[4.5]dec-7-yl]ethyl}-5-methoxy-3-methyl-2H-pyran-2-ylacetic acid; C45H76O16; 113378-31-7; UK-61,689Anticoccidial (veterinary)
O
O
OOOMe
O
O
HO
Me
Me
OH
MeHOOC
Me
Me
Me
HOMe
O
O
Me
OMe
H H
H
H
HO
Me H
H
Semisodium Valproate (BAN) se·mi·sö·dë·um val·prö·ät2-Propylvaleric acid—sodium 2-propylvalerate (1:1); divalproex sodium(USAN); C16H31NaO4; 76584-70-8; DEPAKOTE
Anticonvulsant
H3C CH3
COOH
H3C CH3
COONa•
Sepazonium Chloride se·pa·zö·në·um(RS)-1-[2,4-Dichloro-b-(2,4-dichlorobenzyloxy)phenethyl]-3-phenethyl-imidazolium chloride; C26H23Cl5N2O; 54143-54-3; R 27500Antiseptic
N
N
O
H
ClCl
Cl
Cl
and enantiomer
Cl_
+
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Seractide se·rak·tïd[31-serine]corticotrophin; C207H308N56O58S; 12279-41-3Corticotrophic peptideSeractide has the following amino acid sequence:
Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-
Trp-Gly-Lys-Pro-Val-Gly-Lys-Lys-
Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-
Asp-Ala-Gly-Glu-Asp-Gln-Ser-Ala-
Glu-Ala-Phe-Pro-Leu-Glu-Phe
Sermorelin ser·mo·rë·linC149H246N44O42S; 86168-78-7; GEREF
Diagnostic aid to test secretion of growth hormoneSermorelin has the following amino acid sequence:
Tyr-Ala-Asp-Ala-Ile-Phe-Thr-Asn-
Ser-Tyr-Arg-Lys-Val-Leu-Gly-Gln-
Leu-Ser-Ala-Arg-Lys-Leu-Leu-Gln-
Asp-Ile-Met-Ser-Arg-NH2
Sertaconazole ser·ta·kon·a·zôl(RS)-1-{2-[(7-Chloro-1-benzothien-3-yl)methoxy]-2-(2,4-dichlorophenyl)ethyl}imidazole; C20H15Cl3N2OS; 99592-32-2Antifungal
S
ON
N
Cl
Cl
Cl
H
and enantiomer
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Sertindole ser·tin·dôl1-(2-{4-[5-Chloro-1-(4-fluorophenyl)indol-3-yl]piperidino}ethyl)imidazolidin-2-one; C24H26ClFN4O; 106516-24-9; Lu 23-17; SERDOLECT
Antipsychotic
N
NN
NH
Cl
F
O
Sertraline ser·tra·lën(1S,4S)-4-(3,4-Dichlorophenyl)-1,2,3,4-tetrahydro-1-naphthyl(methyl)-amine; C17H17Cl2N; 79617-96-2Sertraline Hydrochloride 79559-97-0; LUSTRAL
Antidepressant
MeHN
Cl
Cl
H
H
▼Serum GonadotrophinA preparation of a glycoprotein fraction obtained from the serum or plasmaof the pregnant mare capable of stimulating the follicles in the mammalianovary; ¨FOSTIN; ¨P.G. 600*Follicle-stimulating hormone
Setazindol se·ta·zin·dol4¢-Chloro-2-[(methylamino)methyl]benzhydryl alcohol; C15H16ClNO;56481-43-7; PRF 36Appetite suppressant
H OH
NHMe
Cl
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Sevelamer se·ve·la·merAllylamine polymer with 2-chloroethyloxirane; (C3H7N)m·(C3H5ClO)n; 52757-95-6Sevelamer Hydrochloride 182683-00-7Phosphate binder
m
NH2
O
Cl
n
Sevoflurane se·vö·flûr·rän1,1,1,3,3,3-Hexafluoro-2-fluoromethoxypropane; C4H3F7O; 28523-86-6;MR6S4Anaesthetic
F3C OCH2F
H CF3
Sibenadet sï·ben·a·det4-Hydroxy-7-(2-{2-[3-(2-phenylethoxy)propylsulfonyl]ethyl}amino)ethyl-1,3-benzothiazol-2(3H)-one; C22H28N2O5S2Sibenadet Hydrochloride 154189-24-9; ARL 68397AATreatment of respiratory diseases
S
O O
HN O
HNS
O
HO
Sibrafiban sï·bra·fi·banEthyl (Z)-({N-[1-(N-hydroxycarbamimidoyl)benzoyl]-L-alanyl}-4-piperidyloxy)acetate; C20H28N4O6;172927-65-0
Fibrinogen receptor antagonist
NH
N
NHO
NH2
O
O
H MeO
O CH3
O
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Sibutramine sï·bü·tra·mën1-(1-p-Chlorophenylcyclobutyl)-3-methylbutyldimethylamine; C17H26ClN;106650-56-0Sibutramine Hydrochloride 84485-00-7; BTS 54524Antidepressant
and enantiomer
Me
MeCl
Me2NH
Siguazodan sï·gwa·zö·dan(RS)-2-Cyano-1-methyl-3-[4-(4-methyl-6-oxo-1,4,5,6-tetrahydropyridazin-3-yl)phenyl]guanidine; C14H16N6O; 115344-47-3; 99591-83-0;SK&F 94836Inotropic
HNN
N
HN
NHMe
CN
O MeH
and enantiomer
Sildenafil sil·de·na·fil5-[2-Ethoxy-5-(4-methylpiperazin-1-ylsulfonyl)phenyl]-1,6-dihydro-1-methyl-3-propylpyrazolo[4,3-d]pyrimidin-7-one; C22H30N6O4S;139755-83-2Sildenafil Citrate UK-92,480-10; VIAGRA
Selective inhibitor of cyclic GMP specific phosphodiesterase (Type V) with vasodilatoraction; treatment of male erectile dysfunction
HN
N
NN
Me
Prn
SN
MeN
O O
OEt
O
�Simeticone sï·me·ti·köna-(Trimethylsilyl)-w-methylpoly[oxy(dimethylsilylene)], mixture with silicondioxide; 8050-81-5Antiflatulent
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Simvastatin sim·va·sta·tin(1S,3R,7S,8S,8aR)-1,2,3,7,8,8a-Hexahydro-3,7-dimethyl-8-{2-[(2R,4R)-tetrahydro-4-hydroxy-6-oxo-2H-pyran-2-yl]ethyl}-1-naphthyl 2,2-dimethylbutyrate; C25H38O5; 79902-63-9; ZOCOR
Hypolipidaemic
O
O
O
H
Me
HMe
H
Me
OHO
H
H
H
HMeMe
Sincalide sin·ka·lïdDe-1-(5-oxo-L-proline)-de-2-L-glutamine-5-methionine-caerulein
Asp-Tyr(SO3H)-Met-Gly-Trp-Met-Asp-Phe-NH2
C49H62N10O16S3; 25126-32-3Choleretic
Sipatrigine si·pa·tri·jën2-(4-methylpiperazin-1-yl)-5-(2,3,5-trichlorophenyl)pyrimidin-4-amine;C15H16Cl3N5; 130800-90-7; 619C89Treatment of cerebral vascular disease
NH2Cl
N
N N
NMe
Cl
Cl
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Sirolimus si·ro·li·mus(14E,16E,18E,26E)-(7R,8R,11S,13S,20S,22R,24R,25R,28R,31S,33aS)-1,2,3,4,6,7,8,9,10,11,12,13,20,21,22,23,24,25,28,29,30,31,33,33a-tetracosahydro-7,25-dihydroxy-31-{(R)-2-[(1S,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylethyl}-13,24-dimethoxy-8,14,20,22,26,28-hexamethyl-7,11-epoxy-5H-32-oxa-4a-aza-benzocyclohentriacontene-5,6,23,29,33-pentone; C51H79NO13; 53123-88-9; AY-022989;WY-090217T-Lymphocyte inhibitor; immunosupressant
OMe
O
N
O
OMe
OH O
OMe
H
Me
MeMe
H
Me
Me
Me
O
O
O
H
H
OH
OMe
OH
Sisomicin (sissomicin) sis·ö·mï·sinAn antimicrobial base produced by Micromonospora inyoensis(1) 4-O-[(2R,3R)-cis-3-amino-6-aminomethyl-3,4-dihydro-2H-pyran-2-yl]-2-deoxy-6-O-(3-deoxy-4-C-methyl-3-methylamino-b-L-arabinopyranosyl)-streptamine; (2) 2-deoxy-6-O-(3-deoxy-4-C-methyl-3-methylamino-b-L-arabinopyranosyl)-4-O-(2,6-diamino-2,3,4,6-tetradeoxy-D-glycero-hex-4-enopyranosyl)-D-streptamine; C19H37N5O7; 32385-11-8Antibiotic
NH2
OH
O
O
H2N
OHO
O
NH2
HO
Me
NHMeH2N
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Sitamaquine sï·tam·a·quënN,N-Diethyl-N¢-(6-methoxy-4-methyl-8-quinolyl)hexane-1,6-diamine;C21H33N3O; 57695-04-2; WR 6026Sitamaquine Hydrochloride (2HCl) 5330-29-0Antiprotozoal; treatment of leishmaniasis
N
NNEt2
Me
MeO
H
Sodium Acetrizoate sö·dë·um a·së·trï·zö·ätSodium 3-acetamido-2,4,6-tri-iodobenzoate; C9H5I3NNaO3; 129-63-5;DIAGINOL
Contrast medium
COONa
I
I
I
NHAc
Sodium Anoxynaphthonate sö·dë·um a·noks·ë·naf·thö·nätTrisodium 4¢-anilino-8-hydroxy-1,1¢-azonaphthalene-3,5¢,6-trisulfonate;anazolene sodium (pINN; USAN); Coomassie Blue; C26H16N6Na3O10S3;3861-73-2Investigation of cardiac disease
OH
N
NaO3S
NaO3S
N NH
SO3Na
Sodium Antimonylgluconate sö·dë·um an·ti·mo·nïl·gloo·ko·nätSodium salt of an antimony(III) derivative of gluconic acid; C6H8NaO7Sb;16307-91-5Anthelmintic
Sodium Apolate sö·dë·um a·po·lätPoly(sodium ethylenesulfonate); sodium lyapolate; 25053-27-4Anticoagulant
CH2 CH
SO3Na n
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�Sodium Calcium Edetate sö·dë·um kal·së·um e·de·tätCalcium disodium ethylenediaminetetra-acetate; calcium disodiumversenate; C10H12CaN2Na2O8; 62-33-9; LEDCLAIR
Chelating agent
N N
Ca
OO OO
COONaNaOOC
Sodium Cyclamate sö·dë·um sï·kla·mätSodium N-cyclohexylsulfamate; C6H12NNaO3S; 139-05-9Sweetening agent
NH
SO3Na
Sodium Dibunate sö·dë·um dï·bü·nätSodium 2,6-di-tert-butylnaphthalene-1-sulfonate; C18H23NaO3S;14992-59-7Antitussive
Bu t
Bu tSO3Na
Sodium Diprotrizoate sö·dë·um dï·prö·trï·zö·ätSodium 3,5-dipropionamido-2,4,6-tri-iodobenzoate; C13H12I3N2NaO4;129-57-7Contrast medium
COONa
II
I
NCH3N
H3C
OO
HH
�Sodium Feredetate (sodium ironedetate) sö·dë·um fer·e·de·tätIron(III) sodium ethylenediaminetetra-acetate; C10H21FeN2NaO8; 15708-41-5;SYTRON
Treatment of iron-deficiency anaemia
NCH2CH2NCOO
_
COO__
OOC
_OOC
Na+ Fe3+
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�Sodium Glucaldrate (BAN)Sodium diaquagluconato(2-)-O1,O2-dihydroxoaluminate
�Sodium GlucaspaldrateOctasodium di-m-acetato-bis[digluconato(2-)-O1,O2 -salicylato(2-)-aluminate]; C42H54Al2Na8O38; 12214-50-5
HOCH2
H
OH
H
OH H
OH
OH
H
COO
4
Al(CH3COO)2O
COO
2
8Na+ + 2H2O
6_
Sodium Iopodate (sodium ipodate) sö·dë·um ï·ö·pö·dätSodium 3-(3-dimethylaminomethyleneamino-2,4,6-tri-iodophenyl)-propionate; C12H12I3N2NaO2; 1221-56-3; BILOPTIN
Contrast medium
NMe2N
I I
I
COONa
Sodium Ironedetate see Sodium Feredetate
Sodium Metrizoate sö·dë·um me·trï·zö·ätSodium 3-acetamido-2,4,6-tri-iodo-5-N-methylacetamidobenzoate;C12H10I3N2NaO4; 7225-61-8; TRIOSIL*Contrast medium
COONa
II
I
N CH3NH3C
Me
O
H
O
Sodium Phenylbutyrate (BAN)Sodium 4-phenylbutyrate; C10H11NaO2; 1716-12-7Glutamine conjugate; treatment of hyperammonaemia
COONa
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Sodium Picosulfate (sodium picosulphate) sö·dë·um pi·kö·sul·fätDisodium 4,4¢-(2-pyridyl)methylenedi(phenyl sulfate); C18H13NNa2O8S2;10040-45-6; LAXOBERAL; PICOLAX*Laxative
N
OSO3Na
OSO3Na
Sodium Stibocaptate sö·dë·um sti·bö·kap·tätHexasodium salt of 2,2¢-(meso-1,2-dicarboxyethylenedithio)bis(1,3,2-dithiastibolane-4,5-dicarboxylic acid); C12H6Na6O12S6Sb2; 3064-61-7Anthelmintic
SS
COONa
NaOOC
Sb
S
SNaOOC
NaOOC
Sb
S
S
COONa
COONa
�Sodium Stibogluconate sö·dë·um sti·bö·gloo·ko·nätDisodium salt of m-oxy-bis[gluconato(3-)-O2,O3,O4-hydroxoantimony];C12H18Na2O17Sb2 (approximate); 16037-91-5; PENTOSTAM
Antiprotozoan
COONa
OH
HHO
H O
H OH
OH
HHO
HO
H OH
O H
COONa
OH
SbOSb OO
Sodium Timerfonate sö·dë·um ti·mer·fo·nätSodium 4-(ethylmercurithio)benzenesulfonate; C8H9HgNaO3S2; 5964-24-9Preservative
SO3Na
EtHgS
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Sodium Tyropanoate sö·dë·um tîr·rö·pan·ö·ätSodium 2-(3-butyramido-2,4,6-tri-iodobenzyl)butyrate; C15H17I3NNaO3;7246-21-1Contrast medium
I
I I
N CH3
O
H3CHNaOOC
H
and enantiomer
Solapsone (BAN) so·lap·sönTetrasodium 3,3¢-diphenyl-4,4¢-sulfonylbis(1-anilinopropane-1,3-disulfonate); solasulfone (pINN); C30H28N2Na4O14S5; 133-65-3Antileprotic
NaO3S
NH
SO3Na
NH
SO3NaSO3Na
O OS
mixture of isomers
* * **
Solimastat so·lim·a·stat(2S,3R)-3-[(1S)-(2,2-Dimethyl-1-(2-pyridylcarbamoyl)propylcarbamoyl]-2-methoxy-5-methylhexanohydroxamic acid; C20H32N4O5; CAS applied for;BB-3644Inhibitor of metalloproteinases
Me
Me
O NH
CONHOH
H
HMe
MeMe
N
NO
H OMe
H
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Somalapor sö·ma·la·porL-Alanyl-somatotropin (porcine); C977Hl527N265O287S7; 106282-98-8Growth hormone analogue (veterinary)Somalapor has the following amino acid sequence:
AFPAMPLSSL FANAVLRAQH LHQLAADTYK
EFERAYIPEG QRYSIQNAQA AFCFSETIPA
PTGKDEAQQR SDVELLRFSL LLIQSWLGPV
QFLSRVFTNS LVFGTSDRVY EKLKDLEEGI
QALMRELEDG SPRAGQILKQ TYDKFDTNLR
SDDALLKNYG LLSCFKKDLH KAETYLRVMK
CRRFVESSCA F
�Somatostatin sö·ma·tö·sta·tinC76H104N18O19S2; 38916-34-6Growth hormone release inhibitorSomatostain has the following amino acid sequence:
Ala-Gly-Cys-Lys-Asn-Phe-Phe-Trp-
Lys-Thr-Phe-Thr-Ser-Cys
Somatrem sö·ma·tremMethionyl human growth hormone; C995H1537N263O301S8; 82030-87-3;SOMATONORMGrowth hormone analogueSomatrem has the following amino acid sequence:
MFPTIPSRLF DNAMLRLAHR LHQLAFDTYQ
EFEEAYIPKE QKYSFLQNPQ TSLCFSESIP
TPSNREETQQ KSNLELLRIS LLLIQSWLEP
VQFLRSVFAN SLVYGASDSN VYDLLKDLEE
GIQTLMGRLE DGSPRTGQIF KQTYSKFDTN
SHNDDALLKN YGLLYCFRKD MDKVETFLRI
VQCRSVEGSC GF
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Somatropin sö·ma·trö·pinSynthetic human growth hormone; a protein having the normal structure ofthe major (22K) component of natural human growth hormone producedby the pituitary· When produced by synthesis or other artificial means thename, for labelling purposes, carries in parentheses an approved code inlower case letters indicative of the method of production;C990H1528N262O300S7; 12629-01-5; GENOTROPIN; HUMATROPE; NORDIJECT;NORDITROPIN; SAIZEN; ZOMACTON
Growth hormoneThe following codes are approved and others will be made available as theneed arises:
(epr) produced by enzymatic conversion of a precursor produced by abacterium genetically modified by recombinant DNA technology
(rbe) produced from bacteria genetically modified by recombinant DNAtechnology
(rmc) produced from genetically engineered and transformed mammalian(mouse) cells;
Somatropin has the following amino acid sequence:
FPTIPLSRLF DNAMLRAHRL HQLAFDTYQE
FEEAYIPKEQ KYSFLQNPQT SLCFSESIPT
PSNREETQQK SNLELLRISL LLIQSWLEPV
QFLRSVFANS LVYGASDSNV YDLLKDLEEG
IQTLMGRLED GSPRTGQIFK QTYSKFDTNS
HNDDALLKNY GLLYCFRKDM DKVETFLRIV
QCRSVEGSCG F
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Somenopor sö·me·nö·porL-Alanyl-des-(32-38)-somatotropin (porcine); C938H1469N255O275S7; 119693-74-2Growth hormone analogue (veterinary)Somenapor has the following amino acid sequence:
AFPAMPLSSL FANAVLRAQH LHQLAADTYK
EFGQRYSIQN AQAAFCFSET IPAPTGKDEA
QQRSDVELLR FSLLLIQSWL GPVQFLSRVF
TNSLVFGTSD RVYEKLKDLE EGIQALMREL
EDGSPRAGQI LKQTYDKFDT NLRSDDALLK
NYGLLSCFKK DLHKAETYLR VMKCRRFVES
SCAF
Sometribove sö·me·tri·bövMethionyl bovine growth hormone; C978H1540N265O286S9; 102744-97-8Growth hormone analogue (veterinary)Sometribove has the following amino acid sequence:
MFPAMSLSGL FANAVLRAQH LHQLAADTFK
EFERTYIPEG QRYSIQNTQV AFCFSETIPA
PTGKNEAQQK SDLELLRISL LLIQSWLGPL
QFLSRVFTNS LVFGTSDRVY EKLKDLEEGI
LALMRELEDG TPRAGQILKQ TYDKFDTNMR
SDDALLKNYG LLSCFRKDLH KTETYLRVMK
CRRFGEASCA F
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Sometripor sö·me·tri·porMethionyl porcine growth hormone; C979H1527N265O287S8; 102733-72-2Growth hormone analogue (veterinary)Sometripor has the following amino acid sequence:
MFPAPSLSGL FANAVLRAQH LHQLAADYFK
EFEATYIPEG QRYSIQATAV AFCFSETIPA
PTGNNEAQRK SVLELLRISL LLIQSWLGVL
QFLSRVFTNS LVFGTSDRVY EKLKDLEEGQ
LALMRELEDS TPRAGQILKQ TYDKFDTLMR
SDDALLKNYG LLSCYRKDLH ATETYLRVMK
CRRVGSASCA F
Somidobove sö·mï·dö·bövSynthetic bovine growth hormone; C1020H1596N274O302S9; 89383-13-1;L177837; EL349Growth hormone analogue (veterinary)Somidobove has the following amino acid sequence:
MFPLDDDDKF PAMSLSGLFA NAVLRAQHLH
QLAADTFKEF ERTYIPEGQR YSIQNTQVAF
CFSETIPAPT GKNEAQQKSD LELLRISLLL
IQSWLGPLQF LSRVFTNSLV FGTSDRVYEK
LKDLEEGILA LMRELEDGTP RAGQILKQTY
DKFDTNMRSD DALLKNYGLL SCFRKDLHKT
ETYLRVMKCR RFGEASCAF
Sorbinil sor·bi·nil(S)-6-Fluorospiro[chroman-4,4¢-imidazolidine]-2¢,5¢-dione; C11H9FN2O3;68367-52-2; CP-45634Aldose reductase inhibitor
HN
NH
O
O
O
F
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�Sorbitan Laurate (sorbitan monolaurate) sor·bi·tan lor·rätSorbitan monolaurate; C18H34O6; 1338-39-2; SORBESTER P 12; SPAN 20Non-ionic surfactant
O
OH
OH OH
[CH2]10
OHOH
CH3
�Sorbitan Oleate (sorbitan mono-oleate) sor·bi·tan ö·lë·ätSorbitan mono-oleate; sorbitan oleate (rINN); C24H44O6 (approximate);1338-43-8; ̈ NORDERM*; SORBESTER P 17; SPAN 80Non-ionic surfactant
O
OH
OH OH
[CH2]7
OHOH
[CH2]7
HH
CH3
Sorbitan Palmitate (sorbitan monopalmitate) sor·bi·tan parl·mi·tätSorbitan monopalmitate; C22H42O6 (approximate); 26266-57-9; SORBESTER P16; SPAN 40Non-ionic surfactant
O
OH
OH OH
[CH2]14
OHOH
CH3
Sorbitan Sesquioleate ses·kwë·ö·lë·ätSorbitan sesquioleate; C33H60O6·5 (approximate); 8007-43-0; ARLACEL C;ARLACEL 83Non-ionic surfactant
�Sorbitan Stearate (sorbitan monostearate) sor·bi·tan steer·rätSorbitan monostearate; C24H46O6 (approximate); 1338-41-6; MASSE*;SORBESTER P 18; SPAN 60Non-ionic surfactant
O
OH
OH OH
[CH2]16
OHOH
CH3
�Sorbitan Trioleate trï·ö·lë·ätSorbitan trioleate; C60H108O8; 5960-06-5; SORBESTER P 37; SPAN 85Non-ionic surfactant
Sorbitan Tristearate trï·steer·rätSorbitan tristearate; C60H114O8; 26658-19-5; SORBESTER P 38; SPAN 65Non-ionic surfactant
![Page 619: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/619.jpg)
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Sorivudine sor·ri·vü·dën(E)-l-b-D-Arabinofuranosyl-5-(2-bromovinyl)uracil; C11Hl3BrN2O6;77181-69-2; BV-araU; SQ 32,756Antiviral
HO
HN
N
Br
H
H
O
O
HO
OH
O
Sotalol sö·ta·lol4¢-(1-Hydroxy-2-isopropylaminoethyl)methanesulfonanilide; C12H20N2O3S;3930-20-9�Sotalol Hydrochloride 959-24-0; BETA-CARDONE; SOTACOR
Beta-adrenoceptor antagonist
MeS
OO
NH
OHHNHPr i
and enantiomer
Sparfloxacin spar·floks·a·sin5-Amino-l-cyclopropyl-7-(cis-3,5-dimethylpiperazin-l-yl)-6,8-difluoro-l,4-dihydro-4-oxoquinoline-3-carboxylic acid; C19H22F2N4O3; 110871-86-8;AT 4140Antibacterial
HN
N N
COOH
O
F
NH2
F
Me
Me
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4-57
Spectinomycin spek·tin·ö·mï·sinAn antimicrobial substance produced by Streptomyces spectabillis; [(2R)-(2a,4ab,5b,6b,7b,8b,9a,9aa,10ab)]-perhydro-4a,7,9-trihydroxy-2-methyl-6,8-bis(methylamino)pyrano[2,3-b][1,4]benzodioxin-4-one;C14H24N2O7; 1695-77-8; ̈ LINCO-SPECTIN*�Spectinomycin Hydrochloride 22189-32-8 (pentahydrate);21736-83-4 (anhydrous); ̈ SPECTAM; TROBICIN
Antibacterial
O
O
OH
HOH
HMe
OMeHN
HO
MeHN
HO
Spiperone spï·pe·rön8-[3-(4-Fluorobenzoyl)propyl]-1-phenyl-1,3,8-triazaspiro[4.5]decan-4-one; C23H26FN3O2; 749-02-0Antipsychotic
O
N
F
O
N
NH
�Spiramycin spïr·ra·mï·sinAn antimicrobial macrolide antibiotic produced by Streptomyces ambofaciens;8025-81-8; ̈ SPIRA
Antibiotic
Spirapril spir·ra·pril(S)-7-{N-(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl}-1,4-dithia-7-azaspiro[4.4]nonane-8-carboxylic acid; C22H30N2O5S2; 83647-97-6Spirapril Hydrochloride 94841-17-5; Sch 33844Angiotensin-converting enzyme inhibitor
H
S
S
HCOOH
NO
MeHNH
EtOOC
![Page 621: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/621.jpg)
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�Spirilene8-[4-(4-Fluorophenyl)pent-3-enyl]-1-phenyl-1,3,8-triazaspiro[4·5]decan-4-one; C24H28FN3O; 357-66-4
NO
N
NHF
Me
Spirogermanium spïr·rö·jer·mä·në·um3-(8,8-Diethyl-2-aza-8-germaspiro[4.5]dec-2-yl)propyldimethylamine;C17H36GeN2; 41992-23-8Spirogermanium Hydrochloride 41992-22-7Cytotoxic
Ge
N NMe2
Et
Et
�Spironolactone spïr·rö·nö·lak·tön7a-Acetylthio-3-oxo-17a-pregn-4-ene-21,17b-carbolactone; C24H32O4S;52-01-7; ALDACTIDE*; ALDACTONE; LASILACTONE*; SPIRETIC; SPIRO-CO*; SPIROCTAN;SPIROLONE; SPIROSPARE*Diuretic
Me
Me
OO
H
H
H
SAcOH
Spiroplatin spïr·rö·pla·tincis-(Cyclohexylidenedimethylenediamine-N,N¢)(sulfato)platinum;C8H18N2O4PtS; 74790-08-2; TNO-6Cytotoxic
PtNH2
NH2
O
OS
O
O
Stanolone see Androstanolone
![Page 622: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/622.jpg)
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�Stanozolol sta·nö·zö·lol17a-Methyl-2¢H-5a-androst-2-eno[3,2-c]pyrazol-17b-ol; C21H32N2O;10418-03-8; STROMBA
Anabolic steroid; androgen
H
Me
H
H
H
Me OH
Me
NN
H
Stavudine sta·vü·dën1-(2,3-dideoxy-b-D-glycero-pent-2-enofuranosyl)-5-methyluracil;C10H12N2O4; 3056-17-5; ZERIT
Antiviral
O
HO
Me
O
O
N
HN
Stibamine Glucoside sti·ba·mën gloo·kö·sïdSodium [4-(glucopyranosylamino)phenyl]trioxoantimonate;C36H49N3NaO22Sb3; 1344-34-9Antiprotozoan
HO Sb O Sb O Sb ONa
O O
O
NHR NHR
NHR
R = C6H11O5
Stibocaptate see Sodium Stibocaptate
Stilbamidine stil·ba·mi·dënStilbene-4,4¢-dicarboxamidine; C20H28N4O8S2; 140-59-0Antiprotozoan
CHH2N
HNCH
NH2
NH
![Page 623: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/623.jpg)
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Stilbazium Iodide stil·bä·zë·umb,b¢-(1-Ethylpyridinium-2,6-diyl)bis(4-pyrrolidin-1-ylstyrene) iodide;C31H36IN3; 3784-99-4Anthelmintic
I_
CH N CH
Et
N
CH
N
CH+
Stilboestrol see Diethylstilbestrol
�Stirimazolea-(5-Nitro-1-vinylimidazol-2-yl)styrene-4-carboxylic acid; C14H11N3O4;30529-16-9
N
N
COOH
H2C
O2N
Streptodornase strep·tö·dor·näzAn enzyme obtained from cultures of various strains of Streptococcushaemolyticus and capable of catalysing the depolymerisation of polymeriseddeoxyribonucleoproteins; 37340-82-2; VARIDASE*Enzyme
Streptoduocin (BAN)A mixture of equal parts of dihydrostreptomycin sulphate and streptomycinsulphate; ̈ DEVOMYCIN-D
Antibacterial
�Streptokinase strep·tö·kï·näzAn enzyme obtained from cultures of various strains of Streptococcushaemolyticus and capable of changing plasminogen into plasmin;9002-02-1; KABIKINASE; STREPTASE; VARIDASE*Fibrinolytic
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Streptomycin strep·tö·mï·sinO-2-Deoxy-2-methylamino-a-L-glucopyranosyl-(1® 2)-O-5-deoxy-3-C-formyl-a-L-lyxofuranosyl-(1® 4)-N3,N3-diamidino-D-streptamine;C21H39N7O12; 57-92-1�Streptomycin Sulphate 3810-74-0; ̈ DEVOMYCIN; ¨DEVOMYCIN-D*; compo-nent in many other proprietary veterinary preparationsAntitubercular
OCHO
H3C
OH
OOH
HOOH
NH
H2N NH
NH
NH2HN
O
O NHMe
OHHO
OH
�Streptoniazid (streptonicozid)A compound formed by interaction of a suitable streptomycin salt andisoniazid; C27H44N10O12; 4480-58-4
OR
H3C
OH
OOH
HOOH
NH
H2N NH
NH
NH2HN
O
O NHMe
OHHO
OH
CH NN
O
NH
R =
�Styramateb-Hydroxyphenethyl carbamate; C9H11NO3; 94-35-9
OH OH
NH2
O
and enantiomer
![Page 625: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/625.jpg)
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Succimer suks·i·mermeso-2,3-Dimercaptosuccinic acid; C4H6O4S2; 304-55-2Radiodiagnostic aid
COOH
SHH
SHH
COOH
�Succinylsulfathiazole (succinylsulphathiazole) suks·i·nïl·sul·fa·thï·a·zôl4¢-(1,3-Thiazol-2-ylsulfamoyl)succinanilic acid; C13H13N3O5S2;166-43-8Antibacterial
H
N
S
N
SN
OO
HOOC
O
H
Suclofenide sü·klö·fe·nid(RS)-3-Chloro-4-(2-phenylsuccinimido)benzenesulfonamide;C16H13ClN2O4S; 30279-49-3Anticonvulsant
N
O
O
Cl SO2NH2
H
and enantiomer
Sucralfate sü·kral·fätb-D-Fructofuranosyl-a-D-glucopyranoside octakis(hydrogen sulfate),aluminium complex; 54182-58-0; ANTEPSIN
Treatment of gastric and duodenal ulcers
O
OR
OR
R OR O
O
O
R O
OR
OR
OR
R = SO3Al(OH)2
[ Al(OH)3] x [ H2O] y
![Page 626: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/626.jpg)
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Sucralose (BAN) sü·kra·lös1,6-Dichloro-1,6-dideoxy-b-D-fructofuranosyl 4-chloro-4-deoxy-a-D-galactopyranoside; 56038-13-2; C12H19Cl3O8Sweetening agent
HO
Cl
OH
O
Cl
O
ClOH
OHO OH
�SucraloxA polymerised complex of sucrose and aluminium hydroxide; 12040-73-2
Sudoxicam sü·doks·i·kam4-Hydroxy-2-methyl-N-(1,3-thiazol-2-yl)-1,2-benzothiazine-3-carboxamide1,1-dioxide; C13H11N3O4S2; 34042-85-8Analgesic; anti-inflammatory
S
NN
O O
NS
OOH
Me
H
Sufentanil sü·fen·ta·nilN-{4-(Methoxymethyl)-1-[2-(2-thienyl)ethyl]-4-piperidyl}propionanilide;C22H30N2O2S; 56030-54-7; R 30730Sufentanil Citrate 60561-17-3; R 33800Opioid analgesic
N
NCH3
MeO
O
S
![Page 627: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/627.jpg)
4-64
�Sufotidine1-Methyl-3-(mesylmethyl)-1H-1,2,4-triazol-5-yl[3-(a-piperidino-m-tolyl-oxy)propyl]amine; C20H31N5O3S; 80343-63-1
H
NN
NNON
Me
SCH3
OO
�Sulbactam sul·bak·tam(1) (2S,5R)-3,3-Dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide; (2) penicillanic acid 1,1-dioxide; C8H11NO5S;68373-14-8Beta-lactamase inhibitor
N
S
O
H O
O
H COOH
MeMe
Sulconazole sul·kon·a·zôl1-[2,4-Dichloro-b-(4-chlorobenzylthio)phenethyl]imidazole; C18H15Cl3N2S;61318-90-9Sulconazole Nitrate 61318-91-0; EXELDERM
Antifungal
N
N
Cl
Cl
Cl SH
and enantiomer
Sulfacetamide sul·fa·set·a·mïdN-Sulfaniloylacetamide; C8H10N2O3S; 144-80-9; SULTRIN*�Sulphacetamide Sodium 6209-17-2; component in many human andveterinary proprietary preparationsAntibacterial
H2N
SNH
OO
CH3
O
![Page 628: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/628.jpg)
4-65
Sulfabenzamide sul·fa·ben·za·mïdN-Sulfanilylbenzamide; C13H12N2O3S; 127-71-9Antibacterial
O OS
NH
H2N
O
�Sulfacarbamide (sulfaurea) sul·fa·kar·ba·mïdSulfanilylurea; C7H9N3O3S; 547-44-4Antibacterial
H2N
SNH
OO
NH2
O
Sulfachlorpyridazine sul·fa·klor·pi·ri·da·zënN1-(6-Chloropyridazin-3-yl)sulfanilamide; C10H9ClN4O2S; 80-32-0Sulfachlorpyridazine Sodium ¨COSUMIX PLUS
Antibacterial
O O
NH
S
H2N
NN
Cl
Sulfacytine sul·fa·sï·tën(1) N1-(1-Ethyl-1,2-dihydro-2-oxopyrimidin-4-yl)sulfanilamide;(2) 1-ethyl-N-sulfanilylcytosine; sulfacitine (pINN); C12H14N4O3S; 17784-12-2Antibacterial
O O
NH
S
H2N
N
NEt
O
![Page 629: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/629.jpg)
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�Sulfadiazine sul·fa·dï·a·zënN1-(Pyrimidin-2-yl)sulfanilamide; C10H10N4O2S; 68-35-9; ̈ DELVOPRIM*;¨DUPHATRIM*; ̈ EQUITRIM*; ̈ GEATRIM; ̈ NORODINE*; ̈ PORSYN*;¨ SCORPIN; ̈ SYNUTRIM; ̈ SULFATRIM; ̈ TRIBRISSEN; ̈ TRIMABAC; ̈ TRIMEDIAZINE*;¨TRIMEDOXINE; ̈ TRINACOL*; ̈ UNIPRIM*; ̈ VENTIPULMIN TMP/S*Sulfadiazine Silver 22119-08-2; FLAMAZINE
Antibacterial
O O
NH
S
H2N
N
N
Sulfadimethoxine sul·fa·dï·me·thoks·ënN1-(2,6-Dimethoxypyrimidin-4-yl)sulfanilamide; C12H14N4O4S;122-11-2; ̈ QUILIZINE*; ̈ ZAQUILAN*Antibacterial
O O
NH
S
H2N
N
N
OMe
OMe
�Sulfadimidine sul·fa·dï·mi·dënN1-(4,6-Dimethylpyrimidin-2-yl)sulfanilamide; sulfamethazine (USAN);C12H14N4O2S; 57-68-1; ¨BIMADINE; component in many other veterinaryproprietary preparations�Sulfadimidine Sodium ̈ INTRADINE; ¨VESADIN
Antibacterial
O O
NH
S
H2N
N
N
Me
Me
�Sulfadoxine sul·fa·doks·ënN1-(5,6-Dimethoxypyrimidin-4-yl)sulfanilamide; C12H14N4O4S;2447-57-6; ̈ BIMOTRIM CO*; ̈ BORGAL*; FANSIDAR*; ̈ TRIVETRIN*Antibacterial
O O
NH
S
H2N
NN
OMe
OMe
![Page 630: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/630.jpg)
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Sulfaethidole sul·fa·e·thi·dôlN1-(5-Ethyl-1,3,4-thiadiazol-2-yl)sulfanilamide; C10H12N4O2S2;94-19-9Antibacterial
NN
S
H2N
SNH
OO
Et
�Sulfafurazole sul·fa·fûr·ra·zôlN1-(3,4-Dimethyl-1,2-oxazol-5-yl)sulfanilamide; sulfisoxazole (USAN);C11H13N3O3S; 127-69-5Antibacterial
NO
H2N
SNH
OO
Me
Me
Sulfaguanidine sul·fa·gwan·i·dën1-Sulfanilylguanidine; C7H10N4O2S; 56-67-0; ̈ KAOBIOTIC*Antibacterial
H2N
SNH
OO
NH2
NH
Sulfaloxic Acid sul·fa·loks·ik4¢-[(Hydroxymethylcarbamoyl)sulfamoyl]phthalanilic acid; C16H15N3O7S;14376-16-0Calcium Sulfaloxate ENTEROMIDE*Antibacterial
NH
SNH
OO
NH
O
OH
O
HOOC
�Sulfamerazine sul·fa·me·ra·zënN1-(4-Methylpyrimidin-2-yl)sulfanilamide; C11H12N4O2S; 127-79-7Antibacterial
O O
NH
S
H2N
N
N
Me
![Page 631: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/631.jpg)
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�Sulfamethizole sul·fa·me·thi·zôlN1-(5-Methyl-1,3,4-thiadiazol-2-yl)sulfanilamide; C9H10N4O2S2;144-82-1Antibacterial
NN
S
H2N
SNH
OO
Me
�Sulfamethoxazole sul·fa·me·thoks·a·zôlN1-(5-Methyl-1,2-oxazol-3-yl)sulfanilamide; C10H11N3O3S; 723-46-6;BACTRIM*; CHEMOTRIM*; FECTRIM*; LARATRIM*; SEPTRIN*Antibacterial
ON
H2N
SNH
OO
Me
Sulfamethoxypyridazine sul·fa·me·thoks·ë·pi·ri·da·zënN1-(6-Methoxypyridazin-3-yl)sulfanilamide; C11H12N4O3S; 80-35-3;¨BIMALONG; ̈ MIDICEL; ̈ SULFOXINE LA
Antibacterial
O O
NH
S
H2N
NN
OMe
Sulfametopyrazine sul·fa·me·tö·pï·ra·zënN1-(3-Methoxypyrazin-2-yl)sulfanilamide; sulfalene (pINN; USAN);C11H12N4O3S; 152-47-6; KELFIZINE WAntibacterial
O O
NH
S
H2N
N
N
OMe
Sulfametoxydiazine sul·fa·me·toks·ë·dï·a·zënN1-(5-Methoxypyrimidin-2-yl)sulfanilamide; sulfameter (USAN);C11H12N4O3S; 651-06-9Antibacterial
O O
NH
S
H2N
N
NOMe
![Page 632: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/632.jpg)
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Sulfametrole sul·fa·me·trôlN1-(4-Methoxy-1,2,5-thiadiazol-3-yl)sulfanilamide; C9H10N4O3S2;32909-92-5Antibacterial
N
SN
H2N
SNH
OO
OMe
Sulfamonomethoxine sul·fa·mo·nö·me·thoks·ënN1-(6-Methoxypyrimidin-4-yl)sulfanilamide; C11H12N4O3S; 1220-83-3Sulfamonomethoxine Sodium 38006-08-5Antibacterial
O O
NH
S
H2N
NN
OMe
�Sulfamoprine (BAN)N1-(4,6-Dimethoxypyrimidin-2-yl)sulfanilamide; C12H14N4O4S; 155-91-9
O O
NH
S
H2N
N
N
OMe
OMe
Sulfamoxole sul·fa·moks·ôlN1-(4,5-Dimethyl-1,3-oxazol-2-yl)sulfanilamide; C11H13N3O3S; 729-99-7Antibacterial
N
O
H2N
SNH
OOMe
Me
Sulfanitran sul·fa·nï·tran4¢-(4-Nitrophenylsulfamoyl)acetanilide; C14H13N3O5S; 122-16-7Antibacterial
O O
NH
S
AcHN
NO2
![Page 633: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/633.jpg)
4-70
Sulfaphenazole sul·fa·fe·na·zôlN1-(1-Phenylpyrazol-5-yl)sulfanilamide; C15H14N4O2S; 526-08-9Antibacterial
NN
H2N
SNH
OO
Sulfaproxyline sul·fa·proks·ë·lënN1-(4-Isopropoxybenzoyl)sulfanilamide; C16H18N2O4S; 116-42-7Antibacterial
O O
NH
S
H2N
O
OPr i
�Sulfapyrazole sul·fa·pi·ra·zôlN1-(3-Methyl-1-phenylpyrazol-5-yl)sulfanilamide; C16H16N4O2S;852-19-7Antibacterial
NN
H2N
SNH
OOMe
�Sulfapyridine sul·fa·pi·ri·dënN1-(2-Pyridyl)sulfanilamide; C11H11N3O2S; 144-83-2Antibacterial
O O
NH
S
H2N
N
▼Sulfaquinoxaline sul·fa·kwi·noks·a·lënN1-Quinoxalin-2-ylsulfanilamide; C14H12N4O2S; 59-40-5Sulfaquinoxaline Sodium 967-80-6; ̈ DUPHATRIM POULTRY FORMULA*Coccidiostat
O O
NH
S
H2N
N
N
![Page 634: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/634.jpg)
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Sulfasalazine sul·fa·sal·a·zën4-Hydroxy-4¢-(2-pyridy1lsulfamoyl)azobenzene-3-carboxylic acid;salazosulfapyridine (pINN); salicylazosulfapyridine; C18H14N4O5S;599-79-1; SALAZOPYRIN
Antibacterial
O O
NH
S
N
N
N
COOH
HO
�SulfasomizoleN1-(3-Methyl-1,2-thiazol-5-yl)sulfanilamide; C10H11N3O2S; 632-00-8
NS
H2N
SNH
OOMe
�Sulfathiazole sul·fa·thï·a·zôlN1-(1,3-Thiazol-2-yl)sulfanilamide; C9H9N3O2S2; 72-14-0; AMETHOZOL*;SEPTREX*; SULTRIN*▼Sulfathiazole Sodium 144-747-1; 6791-71-5 (pentahydrate)Antibacterial
N
S
H2N
SNH
OO
Sulfathiourea sul·fa·thï·ö·ûr·rë·aSulfanilylthiourea; C7H9N3O2S2; 515-49-1Antibacterial
H2N
SNH
OO
NH2
S
Sulfatolamide sul·fa·tol·a·mïdSulfanilylthiourea salt of a-amino-p-toluenesulfonamide; C7H9N3O2S2;1161-88-2Antibacterial
H2N
SNH
OO
NH2
S
SOO
NH2
H2N
![Page 635: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/635.jpg)
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Sulfatroxazole sul·fa·troks·a·zôlN1-(4,5-Dimethy-1,2-oxazol-3-yl)sulfanilamide; C11H13N3O3S;23256-23-7; ̈ LEOTROX*Antibacterial
ON
H2N
SNH
OO
Me
Me
Sulfaurea see Sulfacarbamide
�Sulfinpyrazone sul·fin·pi·ra·zön1,2-Diphenyl-4-(2-phenylsulfinylethyl)pyrazolidine-3,5-dione;C23H20N2O3S; 57-96-5; ANTURAN
Uricosuric
N
N
O
S
OO
�Sulfiram (monosulfiram) sul.fi.ramTetraethylthiuram monosulfide; C10H20N2S3;95-05-6; ̈ OTERNA*; TETMOSOL
Parasiticide
Et2N S NEt2
S S
Sulfisomidine sul·fï·so·mi·dënN1-(2,6-Dimethylpyrimidin-4-yl)sulfanilamide; C12H14N4O2S; 515-64-0Antibacterial
O O
NS
H2N
NN
Me
MeH
Sulfomyxin Sodium sul·fö·miks·inA mixture of sulfomethylated polymyxin B and sodium bisulfite;C61H103N16Na5O28S; 1405-52-3Antibiotic
Sulglicotide (sulglycotide) sul·glï·kö·tïdThe sulfuric polyester of a glycopeptide isolated from pig duodenum;54182-59-1Sulglicotide SodiumTreatment of peptic ulcer
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�Sulindac sul·in·dak(Z)-5-Fluoro-2-methyl-1-(4-methylsulfinylbenzylidene)indene-3-acetic acid;C20H17FO3S; 38194-50-2; CLINORIL
Analgesic; anti-inflammatory
MeS
COOH
Me
O
F
Suloctidil su·lok·ti·dilerythro-1-[4-(Isopropylthio)phenyl]-2-octylaminopropan-1-ol; C20H35NOS;54063-56-8Vasodilator
NH[ CH2]7CH3
H OH
H MePr i S
and enantiomer
Sulofenur sü·lö·fe·nûr1-(4-Chlorophenyl)-3-(indan-5-ylsulfonyl)urea; C16H15ClN2O3S;110311-27-8; LY186641Antineoplastic
H
O O
NS
N
ClO
H
Sulotroban sü·lö·trö·ban4-(2-Phenylsulfonylaminoethyl)phenoxyacetic acid; C16H17NO5S;72131-33-0; SK&F 95587Thromboxane antagonist
O O
NS
O COOH
H
Sulpha drugs see corresponding name beginning 'Sulfa-'
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Sulphan Blue (BAN)Sodium a-(4-Diethylaminophenyl)-a-(4-diethyliminiocyclohexa-2,5-dienylidene)toluene-2,5-disulfonate; isosulfan blue (USAN); Blue VRS;C27H31N2NaO6S2; 68238-36-8; DISULPHINE BLUE
Investigations of the cardiovascular system
Et2N
NEt2
SO3Na
_O3S
+
Sulphobromophthalein (BAN) sul·fö·brö·mö·fthä·lën5,5¢-(4,5,6,7-Tetrabromo-3-oxo-(3H)-isobenzofuran-1-ylidene)bis-(2-hydroxybenzenesulfonic acid); C20H10Br4O10S; 297-83-6Sulphobromophthalein Sodium 71-67-0Diagnostic aid
O
Br
Br
Br
Br
O
OH
SO3H
SO3H
OH
�Sulpiride sul·pi·rïd(RS)-N-(1-Ethylpyrrolidin-2-ylmethyl)-2-methoxy-5-sulfamoylbenzamide;C15H23N3O4S; 15676-16-1; DOLMATIL; SULPAREX; SULPITIL
Antipsychotic
NO
HN
OMe
H2NS
OO
Et
H
and enantiomer
![Page 638: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/638.jpg)
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�Sultamicillin sul·ta·mi·si·linPenicillanoyloxymethyl (6R)-6-(D-2-phenylglycylamino)penicillanate S¢,S¢-dioxide; C25H30N4O9S2; 76497-13-7; CP-49,952
H
N
S
O
O
O
O
HH
Me
Me
H
S
O
HH2N
O N
N
H O
MeMe
OOH
Sultiame (sulthiame) sul·tï·äm4-(Tetrahydro-2H-1,2-thiazin-2-yl)benzenesulfonamide S,S-dioxide;C10H14N2O4S2; 61-56-3Anticonvulsant
O O
NH2S
O O
NS
Sumacetamol sü·ma·se·ta·mol4-Acetamidophenyl N-acetyl-DL-methioninate; C15H20N2O4S;69217-67-0; SUR 2647Analgesic
OSMe
AcHNO
H NHAc
and enantiomer
Sumatriptan sü·ma·trip·tan3-(2-Dimethylaminoethyl)indol-5-yl-N-methylmethanesulfonamide;C14H21N3O2S; 103628-46-2;Sumatriptan Succinate 103628-48-4; IMIGRAN
5HT1D-Serotonin receptor agonist
Me2NS
NMe2
NH
O O
![Page 639: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/639.jpg)
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Suprofen sü·prö·fen2-[4-(2-Thenoyl)phenyl]propionic acid; C14H12O3S; 40828-46-4;R 25061Analgesic; anti-inflammatory
COOH
H Me
S
O
and enantiomer
Suriclone sûr·ri·klön(RS)-6-(7-Chloro-1,8-naphthyridin-2-yl)-2,3,6,7-tetrahydro-7-oxo-5H-[1,4]dithi-ino[2,3-c]pyrrol-5-yl 4-methylpiperazine-1-carboxylate;C20H20ClN5O3S2; 53813-83-5; 31264 RPAnxiolytic; hypnotic
N NN
S
S
ON
NMe
O
Cl
OH
and enantiomer
�Sutilains sü·ti·länsProteolytic enzymes derived from Bacillus subtilis; 12211-28-8Enzyme
Suxamethonium Bromide suks·a·me·thö·në·um2,2¢-Succinyldioxybis(ethyltrimethylammonium) dibromide; C14H30Br2N2O4;55-94-7Neuromuscular blocker
Me3NO
ONMe3
O
O+
+2Br
_
�Suxamethonium Chloride suks·a·me·thö·në·um2,2¢-Succinyldioxybis(ethyltrimethylammonium) dichloride; succinylcholinechloride (USAN); C14H30Cl2N2O4; 71-27-2; (anhydrous); 6101-15-1 (dihydrate);ANECTINE; SCOLINE
Neuromuscular blocker
Me3NO
ONMe3
O
O
2Cl_+
+
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Suxethonium Bromide suks·e·thö·në·um2,2¢-Succinyldioxybis(diethyldimethylammonium) dibromide;C16H34Br2N2O4; 54063-57-9Neuromuscular blocker
Me2NO
ONMe2
O
O
EtEt
2Br_+
+
�SyrosingopineMethyl O-(4-ethoxycarbonyloxy-3,5-dimethoxybenzoyl)reserpate;C35H42N2O11; 84-36-6
NN
O
O
OMe
MeOOC
MeOH
H
H
O OEt
OMe
OOMe
H
Tacalcitol ta·kal·si·tol(5Z,7E)-(1S,3R,24R)-9,10-Secocholesta-5,7,10(19)-triene-1,3,24-triol;C27H44O3; 57333-96-7; CURATODERM
Treatment of psoriasis
H
MeMe
H
Me
Me
H
H OH
H2C
HO
HO
Tacrine ta·krën1,2,3,4-Tetrahydroacridin-9-ylamine; C13H14N2; 321-64-2Tacrine Hydrochloride 1684-40-8; THAAnticholinesterase
N
NH2
![Page 641: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/641.jpg)
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Tacrolimus ta·kro·li·mus(E)-(7R,8R,10S,11R,12S,14S,18R,21S,22R,23S)-18-allyl-1,2,3,4,6,7,8,9,10,11,12,13,14,15,18,19,20,21,22,23,25,25a-Docosahydro-7,21-dihydroxy-23-{(E)-2-[(1R,3R,4R)-4-hydroxy-3-methoxycyclohexyl]-1-methylvinyl}-10,12-dimethoxy-8,14,16,22-tetramethyl-7,11-epoxy-5H-24-oxa-4a-azabenzocyclotricosene-5,6,19,25-tetrone; C44H69NO12;104987-11-3; PROGRAF
Immunosuppressant
OOMe
H
Me
O
O
OMe
Me
MeN
Me
H
OH
H
O
H
OMe
O
Me
OH
HOH O
CH2
Tafenoquine ta·fen·ö·kwën(RS)-N4-[2,6-Dimethoxy-4-methyl-5-(3-trifluoromethylphenoxy)quinolin-8-yl]pentane-1,4-diamine; 106635-80-7; C24H28F3N3O3; WR 238605Tafenoquine Succinate 106635-81-8Antimalarial
N
MeO
Me
HNNH2
MeH
OMe
OF3C
and enantiomer
![Page 642: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/642.jpg)
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�Talampicillin tal·am·pi·si·lin(RS)-Phthalidyl (6R)-6-(a-D-phenylglycylamino)pencillanate; C24H23N3O6S;47747-56-8Antibacterial
NH
NO
H2N H
O
S
H
Me
Me
H H
O
O O
O
H
*
and epimer at C*
�Taloximine4-(2-Dimethylaminoethoxy)phthalazin-1(2H)-one oxime; C12H16N4O2;17243-68-4
NH
N
N
OH
ONMe2
Tameridone ta·me·ri·dön3,7-Dihydro-7-{2-[4-(indol-3-yl)piperidino]ethyl}-1,3-dimethylpurine-2,6(1H)-dione; C22H26N6O2; 104269-99-0; R51163Sedative (veterinary)
N
N
N
N
N
N
Me
Me
O
O
H
Tamitinol ta·mi·ti·nol4-(Ethylaminomethyl)-2-methyl-5-(methylthiomethyl)pyridin-3-ol;C11H18N2OS; 59429-50-4Used in diffuse cerebral disease
NMe
SMe
NHEt
HO
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Tamoxifen ta·moks·i·fen(Z)-2-[p-(1,2-Diphenylbut-1-enyl)phenoxy]ethyldimethylamine; C26H29NO;10540-29-1�Tamoxifen Citrate 54965-24-1; EMBION; FENTAMOX; NOVALDEX; OESTRIFEN;TAMOFEN
Oestrogen receptor antagonist
H3C
ONMe2
Tamsulosin tam·sü·lö·sin(R)-5-{2-[2-(2-Ethoxyphenoxy)ethylamino]propyl}-2-methoxybenzenesulfonamide; C20H28N2O5S; 106133-20-4Tamsulosin Hydrochloride 106463-17-6; ALPHLO; FLOMAX
Alpha1A-adrenoceptor antagonist; antineoplastic
O
OEt
NH
SO2NH2
OMeH Me
Tandospirone tan·do·spi·rön(1R*,2S*,3R*,4S*)-N-{4-[4-(Pyrimidin-2-yl)piperazin-1-yl]butyl}-8,9,10-trinorbornane-2,3-dicarboximide (1:1); C21H29N5O2; 87760-53-0;SM-3997Tandospirone Citrate 112457-95-1Anxiolytic; 5HT1A-serotonin receptor agonist
N
H
H
O
O
N
N
N
N
Targinine tar·ji·nënNw-Methyl-L-arginine; C7H16N4O2; 17035-90-4; 546C88Inhibition of nitric oxide synthase; treatment of septic shock
NMeHNCOOH
NH
NH2HH
![Page 644: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/644.jpg)
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Tasonermin ta·son·er·minTumour necrosis factor (TNF) alfa-1a (human); C778H1225N215O231S2; 94948-59-1AntineoplasticTasonermin has the following amino acid sequence:
VRSSSRTPSD KPVAHVVANP QAEGQLQWLN
RRANALLANG VELRDNQLVV PSEGLYLIYS
QVLFKGQGCP STHVLLTHTI SRIAVSYQTK
VNLLSAIKSP CQRETPEGAE AKPWYEPIYL
GGVFQLEKGD RLSAEINRPD YLDFAESGQV
YFGIIAL
Tasosartan ta·sö·sar·tan5,8-Dihydro-2,4-dimethyl-8-[4-(o-1H-tetrazol-5-ylphenyl)benzyl]pyrido-[2,3-d]pyrimidin-7(6H)-one; C23H21N7O; 145733-36-4Angiotensin-II receptor antagonist; antihypertensive
N
NN
HN
N
N
N
O
MeMe
�Taurolidine4,4¢-Methylenebis(perhydro-1,2,4-thiadiazine 1,1-dioxide); C7H16N4O4S2;19388-87-5
NH
S
NO
N
NS O
OO H
Tauroselcholic Acid tor·rö·sel·kö·likN-[3a,7a,12a-Trihydroxy-23,24-dinor-5b-cholan-22-ylselenoacetyl]taurine;C26H45NO7SSe; 75018-71-2; SeHCATDiagnostic aid
HO
Me
Me
H
H
H
H
OH
OH SeNH
Me
O
SO3H
H
H
![Page 645: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/645.jpg)
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Taurultam tor·rul·tamPerhydro-1,2,4-thiadiazine 1,1-dioxide; C3H8N2O2S; 38668-01-8Antibacterial; antifungal
SNH
OO
NH
Tazarotene ta·za·rö·tënEthyl 6-[(4,4-dimethylthiochroman-6-yl)ethynyl]nicotinate; C21H21NO2S;118292-40-3; ZORAC
Treatment of retinoid-responsive dermatoses
S
Me Me
NCOOEt
Tazasubrate tä·za·sü·brät2-[(6-Ethoxy-1,3-benzothiazol-2-yl)thio]-2-phenylpropionic acid;C18H13NO3S2; 79071-15-1; EMD 34853Hypolipidaemic
N
S SEtO
Me COOH
and enantiomer
Tazobactam ta·zö·bak·tam(1) (2S,3S,5R)-3-Methyl-7-oxo-3-(1H-1,2,3-triazol-1-ylmethyl)-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid 4,4-dioxide;(2) (2S)-C 2-(1H-1,2,3-triazol-1-yl)penicillinic acid S,S-dioxide;C10H12N4O5S; 89786-04-9; TAXOCINT*Beta-lactamase inhibitor
N
S
O
H O
O
H COOH
Me NN
N
![Page 646: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/646.jpg)
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Teceleukin te·se·loo·kinMethiony linterleukin-2; C698H1127N179O204; 94218-75-4Immunoregulator; antiviralTeceleukin has the following amino acid sequence:
MAPTSSSTKK TQLQLEHLLL DLQMILNGIN
NYKNPKLTRM LTFKFYMPKK ATELKHLQCL
EEELKPLEEV LNLAQSKNFH LRPRDLISNI
NVIVLELKGS ETTFMCEYAD ETATIVEFLN
RWITFCQSII STLT
Technetium[99mTc] Bicisate tek·në·së·um bï·si·sät(SPY-5-23)-[N,N¢-Ethylenebis(ethyl L-cysteinato)-S,S¢,N,N¢-(3-)]oxo[99mTc]technetium(V); C12H21N2O5S2Tc; 121281-41-2Brain perfusion imaging agent
99mTc
ON N
S
EtOOC COOEt
S
Technetium[99mTc] Sestamibi tek·në·së·um ses·ta·mi·bëHexakis(2-methoxy-2-methylpropyl isocyanide)technetium(I)[99mTc] cation;99mTc[C6H11NO]6
+; 109581-73-9; Tc99m RP-30A; CARDIOLITE
Cardiac perfusion radiopharmaceutical
99mTc
N
OMe
MeMe
N
MeO
MeMe
N
OMe
MeMe
N
MeOMe
Me
N
OMeMeMe
N
OMe
MeMe
![Page 647: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/647.jpg)
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Technetium[99mTc] Teboroxime tek·në·së·um te·bor·roks·ëm(TPRS-7-1-232¢4¢54)-Bis[(1,2-cyclohexanedione dioximato)(1-)-O][(1,2-cyclohexanedione dioximato)(2-)-O]methylborato(2-)-N,N¢,N¢¢,N¢¢¢,N¢¢¢¢,N¢¢¢¢¢]-chloro[99mTc]technetium(III); C19H29BClN6O6Tc;104716-22-5; SQ30,217Cardiac imaging agent
N
N
O
99mTc
N
NCl
OB
_O ONN
Me
OH OH
Technetium[99mTc] Tiatide tek·në·së·um tï·a·tïdSodium [N-(mercaptoacetyl)glycylglycylglycinato(1-)-N,N¢,N¢¢,S]oxo-technetate(2-); C8H8N3NaO6STc; 104348-91-6 (anion)Radiodiagnostic aid to renal scintigraphy
99mTc
ON N
SN
O
O
O
COONa
Teclothiazide te·klö·thï·a·zïd(RS)-6-Chloro-3,4-dihydro-3-trichloromethyl-2H-1,2,4-benzothiadiazine-7-sulfonamide 1,1-dioxide; C8H7Cl4N3O4S2; 4267-05-4Diuretic
H2N
O OS
O OS
NH
NH
CCl3HCl
and enantiomer
![Page 648: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/648.jpg)
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Tegafur teg·a·fûr5-Fluoro-1-(tetrahydro-2-furyl)uracil; C8H9FN2O3; 17902-23-7Cytotoxic
NH
N
O
O
O
F
Tegaserod te·ga·ser·rod1-[(5-Methoxyindol-3-yl)methyleneamino]-3-pentylguanidine; C16H23N5O;145158-71-0
Serotonin-receptor antagonist; treatment of irritable bowel syndromeHN
NNH
NH
OMe
NH
CH3
Teicoplanin tï·kö·plä·ninAn antibiotic obtained from cultures of Actinoplanes teichomyceticus, or thesame substance obtained by any other means; 61036-64-4; Teichomycin A2;TARGOCID
Antibiotic
Telithromycin te·li·thrö·mï·sin(3aS,4R,7R,9R,10R,11R,13R,15R,15aR)-4-Ethyloctahydro-11-methoxy-3a,7,9,11,13,15-hexamethyl-1-{4-[4-(3-pyridyl)imidazol-1-yl]butyl}-10-[(3,4,6-trideoxy-3-dimethylamino-b-D-xylo-hexopyranosyl)oxy]-2H-oxacyclotetradecino[4,3-d][1,3]oxazole-2,6,8,14(1H,7H,9H)-tetrone;C43H65N5O10; 173838-31-8
Antibiotic
N
N
O
Et
MeOMe
Me
Me
Me
O
NMe2
Me
OH
O
Me
O
OMeO
N
O
N
H
O
![Page 649: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/649.jpg)
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Telmisartan tel·mi·sar·tan4¢-{[4-Methyl-6-(1-methylbenzimidazol-2-yl)-2-propylbenzimidazol-1-yl]methyl}biphenyl-2-carboxylic acid; C33H30N4O2; 144701-48-4Angiotensin-II receptor antagonist; antihypertensive
N
N Prn
COOH
NMe
N
Me
Teludipine ta·lü·di·pënDiethyl (4RS)-(E)-4-[2-(2-tert-butoxycarbonylvinyl)phenyl]-2-dimethyl-aminomethyl-1,4-dihydro-6-methylpyridine-3,5-dicarboxylate; C28H38N2O6;108687-08-7; GR 53992X; GX 1296XTeludipine Hydrochloride 108700-03-4; GR 53992B; GX 1296BAntihypertensive
H
OBu t
OH
H
Me
EtOOC COOEt
NMe2N
H
and enantiomer
Temafloxacin te·ma·floks·a·sin(RS)-1-(2,4-Difluorophenyl)-6-fluoro-1,4-dihydro-7-(3-methylpiperazin-1-yl)-4-oxoquinoline-3-carboxylic acid; C21H18F3N3O3; 108319-06-8;A-62254Temafloxacin Hydrochloride 105784-61-0Antibacterial
HN
N N
F
F
COOH
O
F
MeH
and enantiomer
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�Temazepam te·mä·ze·pam7-Chloro-1,3-dihydro-3-hydroxy-1-methyl-5-phenyl-1,4-benzodiazepin-2-one; C16H13ClN2O2; 846-50-4; NORMISON
Hypnotic; anxiolytic
N
NCl
OMe
OH
Temelastine te·me·las·tën2-[4-(5-Bromo-3-methyl-2-pyridyl)butylamino]-5-(6-methyl-3-pyridylmethyl)pyrimidin-4(1H)-one; C21H24BrN5O; 86181-42-2;SK&F 93944Histamine H1-receptor antagonist
NHN
HN
N
Br MeN
O Me
Temocapril te·mö·ka·pril(+)-[(2S,6R)-6-{[(S)-1-(Ethoxycarbonyl)-3-phenylpropyl]amino}-5-oxo-2-(2-thienyl)-1,4-thiazepan-4-yl]acetic acid; C23H28N2O5S2;111902-57-9Temocapril Hydrochloride 110221-44-8; CS-622Angiotensin-converting enzyme inhibitor; antihypertensive
S
H
EtOOC H
NH
COOHO
H
S
N
Temocaprilat te·mö·ka·pri·lat(+)-[(2S,6R)-6-{[(S)-1-Carboxy-3-phenylpropyl]amino}-5-oxo-2-(2-thienyl)-1,4-thiazepan-4-yl]acetic acid; 118292-40-3; C21H24N2O5S2; RNH-5139Angiotensin-converting enzyme inhibitor; antihypertensive
S
H
HOOCH
NH
COOHO
H
S
N
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Temocillin te·mö·si·lin(6S)-6-[2-Carboxy-2-(3-thienyl)acetamido]-6-methoxypenicillanic acid;C16H18N2O7S2; 66148-78-5Temocillin Sodium 61545-06-0; TEMOPEN
Antibacterial
H
Me
Me
COOHH
S
O
HHOOC
O N
NH
S
OMe
and epimer at C*
*
Temoporfin te·mö·por·fin7,8-Dihydro-5,10,15,20-tetrakis(3-hydroxyphenyl)porphyrin;C44H32N4O4; 122341-38-2; mTHPCPhotosensitiser in the photodynamic therapy of cancer
NH N
HO
HO
OH
N HN
OH
Temozolomide te·mö·zo·lö·mïd3,4-Dihydro-3-methyl-4-oxoimidazo[5,1-d][1,2,3,5]tetrazine-8-carboxamide; C6H6N6O2; 85622-93-1; M&B 39831Cytotoxic
N
NN
N
N
CONH2
Me
O
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4-89
Temurtide te·mûr·tïdN-{(R)-2-[(3R,4R,5S,6R)-3-Acetamidotetrahydro-2,5-dihydroxy-6-hydroxymethylpyran-4-yloxy]propionyl}-L-threonyl-D-isoglutamine;C20H34N4O12; 66112-59-2; RS-37449Vaccine adjuvant
O
HO
HO
NHAc
OHO
NN
OMe OH
O CONH2
COOHMe
H
H
H
H
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4-90
Tenecteplase te·nek·te·pläs[103-L-asparagine,117-L-glutamine,296-L-alanine,297-L-alanine,298-L-alanine,299-L-alanine]plasminogen activator (human tissue-type);C2558H3872N738O781S40 (non-glycosylated protein); 191588-94-0Antithrombotic
tenecteplase has the following glycosylated amino acid sequence:
SYQVICRDEK TQMIYQQHQS WLRPVLRSNR
VEYCWCNSGR AQCHSVPVKS CSEPRCFNGG
TCQQALYFSD FVCQCPEGFA GKCCEIDTRA
TCYEDQGISY RGNWSTAESG AECTNWQSSA
LAQKPYSGRR PDAIRLGLGN HNYCRNPDRD
SKPWCYVFKA GKYSSEFCST PACSEGNSDC
YFGNGSAYRG THSLTESGAS CLPWNSMILI
GKVYTAQNPS AQALGLGKHN YCRNPDGDAK
PWCHVLKNRR LTWEYCDVPS CSTCGLRQYS
QPQFR
IKGGLFADIA SHPWQAAIFA AAAASPGERF
LCGGILISSC WILSAAHCFQ ERFPPHHLTV
ILGRTYRVVP GEEEQKFEVE KYIVHKEFDD
DTYDNDIALL QLKSDSSRCA QESSVVRTVC
LPPADLQLPD WTECELSGYG KHEALSPFYS
ERLKEAHVRL YPSSRCTSQH LLNRTVTDNM
LCAGDTRSGG PQANLHDACQ GDSGGPLVCL
NDGRMTLVGI ISWGLGCGQK DVPGVYTKVT
NYLDWIRDNM RP
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4-91
Tenidap te·ni·dap(Z)-5-Chloro-3-(a-hydroxy-2-thenylidene)-2-oxoindoline-1-carboxamide;C14H9ClN2O3S; 120210-48-2; CP-66,248Tenidap Sodium 119784-94-0; CP-66,248-02Analgesic; anti-inflammatory
N
CONH2
O
OH
S
Cl
Teniposide te·ni·pö·sïd(5S,5aR,8aR,9S)-5,8,8a,9-Tetrahydro-5-(4-hydroxy-3,5-dimethoxy-phenyl)-9-[(R)-4,6-O-thenylidene-b-D-glucopyranosyloxy]isobenzofuro[5,6-f][1,3]benzodioxol-6(5aH)-one;C32H32N13S; 29767-20-2; VM 26Cytotoxic
S
MeO OMe
OH
OOH
OH
O
O
H O
H
HH
HO
O
OO
�Tenoxicam te·noks·i·kam4-Hydroxy-2-methyl-N-(2-pyridyl)-2H-thieno[2,3-e][1,2]thiazine-3-carboxamide 1,1-dioxide; C13H11N3O4S2; 59804-37-4; MOBIFLEX
Analgesic; anti-inflammatory
O O
NMeS
S
OH
N
NO
H
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4-92
Teprotide te·prö·tïd
<Glu-Trp-Pro-Arg-Pro-Gln-Ile-Pro-Pro
C53H76N14O12; 35115-60-7; SQ 20881Treatment of hypertension and the diagnosis of renin-dependent hypertension
Terazosin te·rä·zö·sin(±)-6,7-Dimethoxy-2-[4-(tetrahydrofuran-2-carbonyl)piperazin-1-yl]quinazolin-4-ylamine; C19H25N5O4; 63590-64-7Terazosin Hydrochloride 70024-40-7 (hydrate); 63074-08-8 (anhydrous);HYTRIN
Alpha-adrenoceptor antagonist
N
N
N
N
O
NH2
MeO
MeO
O
*
*
mixture of 4 stereoisomers
Terbinafine ter·bi·na·fën(E)-6,6-Dimethylhept-2-en-4-ynyl(methyl)(1-naphthylmethyl)amine;C21H25N; 91161-71-6Terbinafine Hydrochloride 78628-80-5; LAMISIL
Antifungal
N
Bu tMe H
H
Terbucromil ter·bü·krö·mil6,8-Di-tert-butyl-4-oxochromene-2-carboxylic acid; C18H22O4;37456-21-6Prophylaxis of allergic conditions
O
O
COOH
Bu t
Bu t
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4-93
Terbutaline ter·bü·ta·lën2-(tert-Butylamino)-1-(3,5-dihydroxyphenyl)ethanol; C12H19NO3;23031-25-6�Terbutaline Sulphate 23031-32-5; BRICANYL; MONOVENT
Beta-adrenoceptor agonist
NHBut
H OHHO
OHand enantiomer
Terconazole ter·ko·na·zôl1-{4-[2-(2,4-Dichlorophenyl-r-2-(1H-1,2,4-triazol-1-ylmethyl)-1,3-dioxolan-c-4-ylmethoxy]phenyl}-4-isopropylpiperazine; C26H31Cl2N5O3;67915-31-5; R42470Antifungal
OO
N
NN Cl
ClO
N
NPr i
H
and enantiomer
�Terfenadine ter·fe·na·dën1-(4-tert-Butylphenyl)-4-[4-(a-hydroxybenzhydryl)piperidino]butan-1-ol;C32H41NO2; 50679-08-8; ALLER-EZE CLEAR; HISTAFEN; SELDANE; TERFENOR;TERFINAX; TRILUDAN*; UNICHEM*Histamine H1-receptor antagonist
NOH H
OH
Bu t
and enantiomer
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4-94
Terfluranol ter·flûr·ra·nol4,4¢-[(1R,2S)-1-Methyl-2-(2,2,2-trifluoroethyl)ethylene]diphenol;C17H17F3O2; 64396-09-4; BX 428Treatment of mammary carcinoma
OH
HO
H Me
H CF3
Terlipressin ter·li·pres·sinN-[N-(N-Glycylglycyl)glycyl]-8-L-lysine vasopressin; C52H74N16O15S2; 14636-12-5; GLYPRESSIN
Antidiuretic hormone
Gly-Gly-Gly-Cys-Tyr-Phe-Gln-Asn-
Cys-Pro-Lys-Gly-NH2
�Terodiline ter·ro·di·lëntert-Butyl(1-methyl-3,3-diphenylpropyl)amine; C20H27N; 15793-40-5Anticholinergic; calcium antagonist
NHBu t
H Me
and enantiomer
Terpin ter·pin (BAN)cis-p-Menthane-1,8-diol; C10H20O2; 80-53-5Terpin Hydrate 2451-01-6; component in many proprietary preparationsExpectorant
Me
Me OH
HOMe
Tertatolol ter·ta·to·lol1-tert-Butylamino-3-(3,4-dihydro-2H-1-benzothiin-8-yloxy)propan-2-ol;C16H25NO2S; 34784-64-0; S-2395Beta-adrenoceptor antagonist
and enantiomer
S
OOHH
NHBu t
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4-95
�Testosterone tes·to·ste·rön17b-Hydroxyandrost-4-en-3-one; C19H28O2; 58-22-0; ANDROPATCH
�Testosterone Decanoate 5721-91-5; ̈ DURATESTON*; SUSTANON*�Testosterone Enanthate 315-37-7; PRIMOTESTON
�Testosterone Isocaproate 15262-86-9; ̈ DURATESTON*; SUSTANON*▼Testosterone Phenylpropionate 1255-49-8 ̈ ANDROJECT; SUSTANON*�Testosterone Propionate 57-85-2; ̈ DURATESTON*; SUSTANON*; VIRORMONE*Testosterone Undecanoate RESTANDOL
Anabolic steroid; androgen
O
Me
Me
H
H
H
H
OH
�Tetrabenazine te·tra·be·na·zën(±)-1,3,4,6,7,11b-Hexahydro-3-isobutyl-9,10-dimethoxybenzo[a]quinolizin-2-one; C19H27NO3; 58-46-8Movement disorder control
N
O
Bu i
MeO
MeO
*
*
mixture of 4 stereoisomers
Tetracaine/Amethocaine te·tra·kän/a·me·thö·kän2-Dimethylaminoethyl 4-butylaminobenzoate; C15H24N2O2; 94-24-6�Tetracaine Hydrochloride/Amethocaine Hydrochloride 136-47-0;¨̈̈̈̈AMETHOZOL*; AMETOP; ̈̈̈̈̈ AUROTO*; ELUDRIL SPRAY*;MINIMS AMETHOCAINE; NOXYFLEX S*Local anaesthetic
Bun HN
ONMe2
O
�Tetracosactide (tetracosactrin) te·tra·kos·ak·tïdCorticotrophin-(1-24)-tetracosapeptide; cosyntropin (USAN);C136H210N40O31S; 16960-16-0; CORTROSYN; SYNACTHEN
Tetracosactide Acetate SYNACTHEN DEPOT
Corticotrophic peptide
Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-
Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro
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4-96
�Tetracycline te·tra·sï·klën(4S,4aS,5aS,6S,12aS)-4-Dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide; C22H24N2O8; 60-54-8; ALBAMYCIN T*�Tetracycline Hydrochloride 64-75-5; ACHROMYCIN; DETECLO*; SUSTAMYCIN;¨TETSOL; TOPICYCLINE
Antibiotic
OH O HO O
CONH2
OH
NMe2HH
MeHO
OH
Tetracycline Phosphate Complex (BAN)A sparingly soluble complex of sodium metaphosphate and tetracyline;1336-20-5Antibiotic
Tetrahydrozoline see Tetryzoline
Tetramisole te·tra·mi·sôl2,3,5,6-Tetrahydro-6-phenylimadazo[2,1-b][1,3]thiazole; C11H12N2S;5036-02-2Tetramisole Hydrochloride 5386-74-8 ̈ NILVERM PIG WORMER
Anthelmintic
N
NS
H
and enantiomer
Tetrofosmin te·trö·fos·min(1) P,P,P¢,P¢-Tetrakis(2-ethoxyethyl)ethylenebisphosphane;(2) 6,9-bis(2-ethoxyethyl)-3,12-dioxa-6,9-diphosphatetradecane;C18H40O4P2; 127502-06-1; P53Diagnostic agent for radiolabelling with 99mTc; scintigraphic visualisation of ischaemicheart disease after intravenous injection
OH3CP CH2
OH3C
O CH3PCH2
O CH3
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Tetronasin te·tro·na·sinTetrahydro-3-[(S)-1-hydroxy-2-{(1S,2S,6R)-2-[(E)-3-hydroxy-2-{(2R,3R,6S)-tetrahydro-3-methyl-6-[(E)-(S)-3-{(2R,3S,5R)-tetrahydro-5-[(R)-1-methoxyethyl]-2-furyl}but-1-enyl]-3-methyl-2H-pyran-2-yl}prop-1-enyl]-6-methylcyclohexyl}propylidene]furan-2,4-dione; C35H54O8; 75139-06-9; ICI139603Tetronasin Sodium 75139-05-8; ICI 139603Growth promoter (veterinary)
OO
Me
Me
OH
Me
H
HH
Me
H
Me
OMe
HMe
H
H
O
OO
OH
Tetroxoprim te·troks·ö·prim5-[3,5-Dimethyloxy-4-(2-methoxyethoxy)benzyl]pyrimidine-2,4-diyldiamine; C16H22N4O4; 53808-87-0Antibacterial
N
N
NH1
NH2
MeO
OMe
OMeO
Tetryzoline (tetrahydrozoline) te·trï·zö·lën(RS)-2-(1,2,3,4-Tetrahydro-1-naphthyl)-2-imidazoline; C13H16N2; 84-22-0Alpha-adrenoceptor agonist
N NH
H
and enantiomer
Thalidomide tha·li·dö·mïd(RS)-2-Phthalimidoglutarimide; C13H10N2O4; 50-35-1Hypnotic
NNH
O
O
O
O
H
and enantiomer
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4-98
Thaumatin (BAN) thor·ma·tinA mixture in the ratio 2:1 of two polypeptides, thaumatin I and II, eachconsisting of 207 amino acid residues and having a molecular weight ofabout 22,000, extracted from the aril of the tropical fruit Thaumatococcusdaniellii Benth; 53850-34-3; TALIN
Sweetening agent
Thebacon the·ba·kon(1) (-)-(5R,6S)-4,5-Epoxy-3-methoxy-9a-methylmorphin-6-en-6-yl acetate;(2) 6-O-acetyl-7,8-dihydro-3-O-methyl-6,7-didehydromorphine;C20H23NO4; 466-90-0Opioid analgesic; cough suppressant
NMe
O
MeO
H
AcO
Thenalidine the·na·li·dënN-(1-Methyl-4-piperidyl)-N-(2-thenyl)aniline; C17H22N2S; 86-12-4Histamine H1-receptor antagonist
N
NMe
S
▼Thenium Closylate thë·në·um klö·si·lätDimethyl(2-phenoxyethyl)2-thenylammonium 4-chlorobenzenesulfonate;C21H24ClNO4S; 4304-40-9Anthelmintic
ON
Me Me SCl
SO3_+
Thenyldiamine the·nïl·dï·a·mën2-(N-2-Pyridyl-N-3-thenylamino)ethyldimethylamine; C14H19N3S;91-79-2Thenyldiamine Hydrochloride 958-93-0Histamine H1-receptor antagonist
N NNMe2
S
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4-99
�Theobromine thë·ö·brö·mën3,7-Dihydro-3,7-dimethylpurine-2,6(1H)-dione; C7H8N4O2; 83-67-0;SEOMINAL*
HN
N
N
N
O
O
Me
Me
Theodrenaline thë·ö·dren·a·lën7-[2-(3,4,b-Trihydroxyphenethylamino)ethyl]theophylline; C17H21N5O5;13460-98-5Analeptic
and enantiomer
NMe
N
N
N
O
O
Me
HN
OHH
HO
HO
�Theophylline (BAN) thë·o·fi·lën3,7-Dihydro-1,3-dimethylpurine-2,6(1H)-dione; C7H8N4O2; 58-55-9;BIOPHYLLINE*; ̈ CORVENTAL-D; DO-DO*; FRANOL*; FRANOL PLUS*; LABOPHYLLINE;LASMA; NUELIN; SLO-PHYLLIN; THEO-DUR; UNIPHYLLIN
�Theophylline Hydrate (monohydrate); 5967-84-0Bronchodilator
MeN
N
N
N
O
O
Me
H
Thiabendazole see Tiabendazole
Thiacetazone see Thioacetazone
Thialbarbital (thialbarbitone) thï·al·bar·bi·tal5-Allyl-5-(cyclohex-2-enyl)-2-thiobarbituric acid; C13H16N2O2S; 467-36-7Anaesthetic
NH
N S
O
OH2CH
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4-100
Thiamazole (methimazole) thï.am.a.zôl1-Methylimidazole-2-thiol; C4H6N2S; 60-56-0Antithyroid
N
N
Me
SH
Thiambutosine thï·am·bü·tö·sën1-(4-Butoxyphenyl)-3-(4-dimethylaminophenyl)thiourea; C19H25N3OS;500-89-0; CIBA 1906Antileprotic
BunO
N N
NMe2S
HH
Thiamine thï·a·mën[3-(4-Amino-2-methylpyrimidin-5-ylmethyl)-5-(2-hydroxyethyl)-4-methyl-1,3-thiazolium hydroxide; vitamin B1; C12H18N4O2S; 59-43-8�Thiamine Hydrochloride 67-03-8; BENERVA; component of many propri-etary preparations�Thiamine Nitrate 532-43-4; component of many proprietary preparationsVitamin
N
N
S
N
HOMe
NH2Me
+ OH_
�Thiamphenicol thï·am·fe·ni·kol(aR,bR)-2,2-Dichloro-N-(b-hydroxy-a-hydroxymethyl-4-methylsulfonyl-phenethyl)acetamide; C12H15Cl2NO5S; 15318-45-3Antibacterial
N
OHH
H3CSO2
Cl
O
Cl
H
OH
H
Thiazesim see Tiazesim
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4-101
�Thiethylperazine thï·ë·thïl·pe·ra·zën2-Ethylthio-10-[3-(4-methylpiperazin-1-yl)-propyl]phenothiazine;C22H29N3S2; 1420-55-9Antiemetic
S
N N
NMe
SEt
Thioacetazone (thiacetazone) thï·ö·a·set·a·zön4-Acetamidobenzaldehyde thiosemicarbazone; C10H12N4OS; 104-06-3Antitubercular
NH3C
O
NN NH2
S
H
H
Thiocarlide see Tiocarlide
Thioguanine see Tioguanine
�Thiomersal thï·ö·mer·salSodium salt of (2-carboxyphenylthio)ethylmercury; thimerosal;thiomersalate; C9H9HgNa2OS; 54-64-8Anti-infective
COONa
SHgEt
Thiomesterone see Tiomesterone
Thiopental (thiopentone) thï·ö·pen·tal5-Ethyl-5-(1-methylbutyl)-2-thiobarbituric acid; C11H18N2O2S; 76-75-5�Thiopental Sodium 71-73-8; INTRAVAL; ¨THIOVET
Anaesthetic
H
NH
N
O
O S
H3CEt
H Me
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4-102
Thiophanate (BAN) thï·o·fa·nät(1) 4,4¢-o-Phenylenebis(ethyl 3-thioallophanate); (2) 4,4¢-o-phenylenebis(3-ethoxycarbonyl-2-thiourea); C14H18N4O4S2;23564-06-9 ̈ NEMAFAX;Anthelmintic
HN NH OEt
NH NH OEt
S O
S O
�Thiopropazate2-{4-[3-(2-Chlorophenothiazin-10-yl)propylpiperazin-1-yl}ethyl acetate;C23H28ClN3O2S; 84-06-0
S
N N
N
Cl
OAc
Thioproperazine thï·ö·prö·pe·ra·zënN,N-Dimethyl-10-[3-(4-methylpiperazin-1-yl)propyl]phenothiazine-2-sulfonamide; C22H30N4O2S2; 316-81-4Thioproperazine Mesylate 2347-80-0Antipsychotic
S
N N
NMe
SO2NMe2
Thioridazine thï·ö·rid·a·zën(RS)-10-[2-(1-Methyl-2-piperidyl)ethyl]-2-methylthiophenothiazine;C21H26N2S2; 50-52-2�Thioridazine Hydrochloride 130-61-0; MELLERIL
Antipsychotic
S
N
SMe
N
MeH
and enantiomer
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4-103
�Thiotepa thï·ö·të·paPhosphorothioic tri(ethyleneamide); C6H12N3PS; 52-24-4Cytotoxic
N
N NP
S
Thiothixene see Tiotixene
Thioxolone see Tioxolone
�Thonzylamine2-[p-Anisyl(pyrimidin-2-yl)amino]ethyldimethylamine; C16H22N4O;91-85-0
NNMe2
N NMeO
Thurfyl Nicotinate (BAN) ther·fïlTetrahydrofurfuryl nicotinate; C11H13NO3; 70-19-9Vasodilator
O
O
O
N
Thymopentin thï·mö·pen·tinL-arginyl-L-lysyl-a-L-aspartyl-L-valyl-L-tyrosine; C30H49N9O9; 69558-55-0ImmunoregulatorArg–Lys–Asp–Val
Thymoxamine see Moxisylyte
Thyrotrophin thï·rö·trö·finThyrotrophic hormone; 9002-71-5Hormone
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4-104
Thyrotropin Alfa thî·rö·trö·pin al·faThyrotropin (human b-subunit protein moiety), complex with chorionicgonadotropin (human a-subunit protein moiety); 194100-83-9;C1039H1602N274O307S27Thyrotropin analogueThyrotropin alfa has the following amino acid sequence (Cys—Cys bridgingnot shown):
α-subunit:
β-subunit:
APDVQDCPEC TLQENPFFSQ PGAPILQCMG
CCFSRAYPTP LRSKKTMLVQ KNVTSESTCC
VAKSYNRVTV MGGFKVENHT ACHCSTCYYH
KS
FCIPTEYTMH IERRECAYCL TINTTICAGY
CMTRDINGKL FLPKYALSQD VCTYRDFIYR
TVEIPGCPLH VAPYFSYPVA LSCKCGKCNT
DYSDCIHEAI KTNYCTKPQK SYLVGFSV
Thyroxine see Levothyroxine
�Tiabendazole (thiabendazole) tï·a·ben·da·zôl2-(1,3-Thiazol-4-yl)benzimidazole; C10H7N3S; 148-79-8; ̈ AUROTO*;¨EQUIZOLE; MINTEZOL; ̈ RANIZOLE*; ̈ THIBENZOLE
Anthelmintic
N
N N
SH
Tiagabine ti·a·ga·bën(R)-1-[4,4-Bis(3-methyl-2-thienyl)but-3-enyl]piperidine-3-carboxylic acid;C20H25NO2S2; 115103-54-3Tiagabine Hydrochloride 145821-59-6; GABITRIL
Antiepileptic
S
Me
Me
S
N
COOHH
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Tiamenidine tï·a·me·ni·dën2-Chloro-4-methyl-3-thienyl(2-imidazolin-2-yl)amine; C8H10ClN3S;31428-61-2Tiamenidine Hydrochloride 31428-62-3Alpha2-adrenoceptor agonist; antihypertensive
S
N
HN
N
Me
Cl
H
Tiamulin tï·a·mü·lin11-Hydroxy-6,7,10,12-tetramethyl-1-oxo-10-vinylperhydro-3a,7-pentano-inden-8-yl (2-diethylaminoethylthio)acetate; C28H47NO4S; 56142-71-3Tiamulin Fumarate 55297-96-6; ̈ TIAMUTIN
Antibacterial
OMe
MeHO
H2CMe
H Me
OS
O
Et2N
Tiapamil tï·a·pa·mil(RS)-3,4-Dimethoxyphenethyl{3-[2-(3,4-dimethoxyphenyl)-1,3-dithian-2-yl]propyl}methylamine S,S,S¢,S¢-tetraoxide; C26H37NO8S2;57010-31-8; Ro 11-1781Calcium antagonist
SO2O2S OMe
OMe
Me
N
MeO
OMe
H
and enantiomer
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4-106
Tiapride tï·a·prïdN-(2-Diethylaminoethyl)-2-methoxy-5-methylsulfonylbenzamide;C15H24N2O4S; 51012-32-9Tiapride Hydrochloride 51012-33-0; FLO 1347Antipsychotic
Me
O OS
NNEt2
OMe
O
H
�Tiaprofenic Acid tï·a·prö·fë·nik2-(5-Benzoyl-2-thienyl)propionic acid; C14H12O3S; 33005-97-7; SURGAM
Analgesic; anti-inflammatory
O
SCOOH
H Me
and enantiomer
Tiaprost tï·a·prost(1) (5Z,13E)-(9S,11R,15RS)-9,11,15-Trihydroxy-16-(3-thienyloxy)-17,18,19,20 tetranorprosta-5,13-dienoic acid (2) (±)-(Z)-7-{(1R,2R,3R,5S)-3,5-Dihydroxy-2-[(E)-(3RS)-3-hydroxy-4-(3-thienyloxy)buten-1-yl]cyclopentyl}hept-5-enoic acid; C20H28O6S; 71116-82-0Prostanoid luteolytic (veterinary)
and epimer at C*
HO H
HH H
COOH
HO
O
S
OH
H
H
H
*
Tiaramide tï·a·ra·mïd5-Chloro-3-[4-(2-hydroxyethyl)piperazin-1-ylcarbonylmethyl]-1,3-benzothiazol-2(3H)-one; C15H18ClN3O3S; 32527-55-2Analgesic; anti-inflammatory
S
NO
N
N
O
OHCL
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Tiazesim (thiazesim) tï·a·ze·sim5-(2-Dimethylaminoethyl)-2,3-dihydro-2-phenyl-1,5-benzothiazepin-4(5H)-one; C19H22N2OS; 5845-26-1Antidepressant
N
S
OMe2N
Tibolone tï·bo·lön17b-Hydroxy-7a-methyl-19-nor-17a-pregn-5(10)-en-20-yn-3-one;C21H28O2; 5630-53-5; LIVIAL
Oestrogen- and progestrogen-like steroid
O
Me OH
CH
H
H
H
Me
Tibric Acid ti·brik2-Chloro-5-(cis-3,5-dimethylpiperidinosulfonyl)benzoic acid;C14H18ClNO4S; 37087-94-8Hypolipidaemic
N
O OS COOH
Cl
Me
Me
�Ticarbodine2,6-Dimethylpiperidino-3¢-(trifluoromethyl)thioformanilide; C15H19F3N2S;31932-09-9
N N
S
F3C
Me
Me
H *
*
mixture of isomers
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4-108
�Ticarcillin tï·kar·si·lin(6R)-6-[2-Carboxy-2-(3-thienyl)acetamido]penicillanic acid; C15H16N2O6S2;3973-04-4Ticarcillin Sodium 4697-14-7; TICAR; TIMENTIN*Antibacterial
HN
NO
HOOC H
O
S
H COOH
Me
Me
H H
S
and enantiomer at C*
*
Ticlopidine tï·klö·pi·dën5-(2-Chlorobenzyl)-4,5,6,7-tetrahydrothieno[3,2-c]pyridine; C14H14ClNS;55142-85-3�Ticlopidine Hydrochloride 53885-35-1Platelet aggregation inhibitor
N
SCl
Tiemonium Iodide tï·e·mö·në·um4-[3-Hydroxy-3-phenyl-3-(2-thienyl)propyl]-4-methylmorpholinium iodide;C18H24INO2S; 144-12-7Anticholinergic
S
OHN
O
Me
+
I_
and enantiomer
Tienilic Acid tï·e·ni·lik[2,3-Dichloro-4-(2-thenoyl)phenoxy]acetic acid; C13H8Cl2O4S;40180-04-9Antihypertensive; diuretic
S
O
O COOH
Cl
Cl
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4-109
Tiformin (tyformin) tï·for·min4-Guanidinobutyramide; C5H12N4O; 4210-97-3Hypoglycaemic
HN N CONH2
NH2
H
�Tigloidine(1R,3s,5S)-3-[(E)-3-Methylmethacryloyloxy)tropane; C13H21NO2; 495-83-0
NMe
H
O
Me
Me
HO
Tiletamine tï·le·ta·mën(RS)-2-Ethylamino-2-(2-thienyl)cyclohexanone; C12H17NOS; 14176-49-9Tiletamine Hydrochloride 14176-50-2Anticonvulsant; anaesthetic
S
ONHEt
and enantiomer
�TilidateEthyl 2-dimethylamino-1-phenylcyclohex-3-ene-1-carboxylate; tilidine(pINN); C17H23NO2; 20380-58-90
COOEtNMe2
H* *
mixture of 4 stereoisomers
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4-110
Tilmicosin til·mï·kö·sin(10E,12E)-(3R,4S,5S,6R,8R,14R,15R)-14-(6-Deoxy-2,3-di-O-methyl-b-D-allo-hexopyranosyloxymethyl)-5-(3,6-dideoxy-3-dimethylamino-b-D-glucohexopyranosyloxy)-6-[2-(cis-3,5-dimethylpiperidino)ethyl]-3-hydroxy-4,8,12-trimethyl-9-oxoheptadeca-10,12-dien-15-olide; C46H80N2O13;108050-54-0; ̈ MICOTIL
Antibiotic (veterinary)
O HOMe
NMe2
OH
OO
O
Me
Me
OH
O
Me
Et
Me
MeN
O
OMeMeOHO
Me
O
Tiludronic Acid tï·lü·dro·nik(4-Chlorophenylthiomethylene)bisphosphonic acid; C7H9ClO6P2S;89987-06-4Tiludronate Sodium (2Na) 149845-07-8; SKELED
Treatment of Paget’s disease of bone and osteoporosis
P
O
OH
OHP
O
OH
HO C
H
S
Cl
Timolol tï·mo·lol(S)-1-tert-Butylamino-3-(4-morpholino-1,2,5-thiadiazol-3-yloxy)propan-2-ol; C13H24N4O3S; 26839-75-8�Timolol Maleate 26921-17-5; BETIM; BLOCADREN; GLAUCOL: MODUCREN*;PRESTIM*; TIMOPTOL
Beta-adrenoceptor antagonist
N
O
SN N
NHBu t
HO HO
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4-111
�Tinidazole ti·nï·da·zôl1-[2-(Ethylsulfony)ethyl]-2-methyl-5-nitroimidazole; C8H13N3O4S;19387-91-8; FASIGYN
Antiprotozoan; antibacterial
O OS
N
N
CH3
NO2
Me
Tinzaparin Sodium tin·za·pa·rinSodium salt of depolymerised heparin obtained by enzymatic degradation ofheparin from pork intestinal mucosa; the majority of the components have a2-O-sulfo-4-enopyranosuronic acid structure at the non-reducing end oftheir chain and a 2-N,6-O-disulfo-D-glucosamine structure at the reducingend; the molecular weight of 70% of the components lies between 1,500and 10,000 and the average molecular weight is about 4,500; the degree ofsulfation is 2·0 to 2·5 per disaccharide unit; INNOHEP
Anticoagulent
Tiocarlide (thiocarlide) tï·ö·kar·lïd1,3-Bis(4-isopentyloxyphenyl)thiourea; C23H32N2O2S; 910-86-1Antitubercular
OH3C
N N
OS
CH3
CH3
CH3
HH
Tioconazole tï·ö·ko·na·zôl1-[2,4-Dichloro-b-(2-chloro-3-thenyloxy)phenethyl]imidazole;C16H13Cl3N2OS; 65899-73-2; TROSYL
Antifungal
and enantiomer
S Cl
N
N
O
ClCl
H
�Tioguanine (thioguanine) tï·o·gwa·nën2-Aminopurine-6-thiol; C5H5N5S; 154-42-7; LANVIS
Cytotoxic
N
N
N
N
SH
H2N
H
H
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Tiomesterone (thiomesterone) tï·ö·mes·te·rön1a,7a-Bis(acetylthio)-17b-hydroxy-17a-methylandrost-4-en-3-one;C24H34O4S2; 2205-73-4Anabolic steroid; androgen
O
H
H
H
Me OH
MeMe
Me S
O
S
MeO
Tiopinac tï·ö·pi·nak6,11-Dihydro-11-oxodibenzo[b,e]thiepin-3-acetic acid; C16H12O3S;61220-69-7; RS-40974-00-00-0Analgesic; anti-inflammatory
S
O
COOH
Tiotixene (thiothixene) tï·ö·tiks·ën(Z)-N,N-Dimethyl-9-[3-(4-methylpiperazin-1-yl)propylidene]thioxanthene-2-sulfonamide; C23H29N3O2S2; 3313-26-6Antipsychotic
O O
NMe2S
H
NMe
N
S
Tioxaprofen tï·oks·a·prö·fen2-[4,5-Bis(4-chlorophenyl)-1,3-oxazol-2-ylthio]propionic acid;C18H13Cl2NO3S; 40198-53-6Analgesic; anti-inflammatory
Cl
Cl
O
N S COOH
H Me
and enantiomer
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4-113
Tioxolone (thioxolone) tï·oks·o·lön6-Hydroxy-1,3-benzoxathiol-2-one; C7H4O3S; 4991-65-5Keratolytic
O
SO
HO
Tipentosin ti·pen·tö·sin(1S,2S,3S)-5-(2-Hydroxy-3-phenoxycyclopentylaminomethyl)-4,5,6,7-tetrahydro-2-methylbenzo[b]thiophen-4-one; C21H25NO3S;95588-11-7Tipentosin Hydrochloride 90326-86-6; MDL 19744AAntihypertensive
OHN
S
O
OHMe
Tipredane tï·pre·dän17a-(Ethylthio)-9a-fluoro-11b-hydroxy-17b-(methylthio)androsta-1,4-dien-3-one; C22H31FO2S2; 85197-77-9; SQ 27,239Corticosteroid
O
Me
HOMe SEt
SMeH
F H
Tiprenolol tï·pren·o·lol3-Isopropylamino-1-[2-(methylthio)phenoxy]propan-2-ol; C13H21NO2S;26481-51-6Tiprenolol Hydrochloride 39832-43-4Beta-adrenoceptor antagonist
O NHPriOHH
SMe
and enantiomer
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4-114
Tiprostanide tï·prost·a·nïd(1) (±)-4-Benzamidophenyl 7-[(1S*,2R*,3R*)-3-hydroxy-2-(2-hydroxy-2-methylheptylthio)-5-oxocyclopentyl]heptanoate; (2) (±)-4-benzamido-phenyl 11,15-dihydroxy-15-methyl-9-oxo-13-thiaprostanoate; C33H45NO6S;67040-53-3Antihypertensive
SCH3
H
H OHMeHO
O
ON O
O
H
and enantiomer
Tiquinamide tï·kwi·na·mïd5,6,7,8-Tetrahydro-3-methylquinoline-8-carbothioamide; C11H14N2S;53400-67-2Tiquinamide Hydrochloride 53400-68-3Gastric antisecretory
N
CSNH2
Me
Tirilazad ti·ri·la·zad21-{4-[2,6-(Dipyrrolidin-1-yl)pyrimidin-4-yl]piperazin-1-yl}-16a-methylpregna-1,4,9(11)-triene-3,20-dione; C38H52N6O2; 110101-66-1Tirilazad Mesylate 111793-42-1; U-74,006FLipid peroxide inhibitor; oxygen-derived free radical scavenger
N
N
NN
N
NO
O
Me
Me
H
HMe
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4-115
Tirofiban tï·rö·fï·banN-(Butylsulfonyl)-O-[4-(piperidin-4-yl)butyl]-L-tyrosine; C22H36N2O5S;144494-65-5Tirofiban Hydrochloride 150915-40-5; MK-383; L-700,462Fibrinogen receptor antagonist; treatment of unstable angina
O
NH
HOOCH
BunSOO
HN
Tixocortol tiks·ö·kor·tol11b,17a-Dihydroxy-21-mercaptopregn-4-ene-3,20-dione; C21H30O4S;61951-99-3Tixocortol Pivalate JO 1016Corticosteroid
O
Me
HOMe SHO
H H
HOH
Tizanidine tï·za·ni·dën5-Chloro-2,1,3-benzothiadiazol-4-yl(2-imidazolin-2-yl)amine; C9H8ClN5S;51322-75-9Tizanidine Hydrochloride ZANAFLEX
Muscle relaxant
N
SN
N
NH
NHCl
Tizolemide tï·zo·le·mïd(RS)-2-Chloro-5-[4-hydroxy-3-methyl-2-(methylimino)-1,3-thiazolidin-4-yl]-benzenesulfonamide; C11H14ClN3O3S2; 56488-58-5Tizolemide Hydrochloride Hoe 740; S73 0740BDiuretic
N
S
Cl
O OS
NH2HOMe
MeN
and enantiomer
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4-116
�Tobramycin to·bra·mï·sinAn antimicrobial base produced by Streptomyces tenebrarius; 6-O-(3-amino-3-deoxy-a-D-glucopyranosyl)-2-deoxy-4-O-(2,6-diamino-2,3,6-trideoxy-a-D-ribo-hexopyranosyl)-D-streptamine; C18H37N5O9; 32986-56-4; TOBRALEX
Tobramycin Sulphate 49842-07-1; NEBCIN
Antibiotic
NH2NH2
OH
O
O
H2N
OOH
HO
O
HO
H2N
HO
NH2
Tocainide to·kä·nïd(1) Alanino-2¢,6¢-xylidide; (2) 2-aminopropiono-2¢,6¢-xylidide; C11H16N2O;41708-72-9Tocainide Hydrochloride 35891-93-1; TONOCARD
Antiarrhythmic
NNH2
Me
MeO
H MeH
and enantiomer
Tocladesine to·kla·de·sën8-Chloroadenosine 3¢,5¢-(hydrogen phosphate); 41941-56-4; C10H11ClN5O6P
Immunomodulator
O
N
NN
N
O
OHOPO
OH
Cl
NH2
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4-117
Todralazine to·dra·la·zënEthyl 3-(phthalazin-1-yl)carbazate; C11H12N4O2; 14679-73-3Vasodilator
N
N
HNN
COOEt
H
�Tofenacin(RS)-Methyl-2-(2-methylbenzhydryloxy)ethylamine; C17H21NO; 15301-93-6
ONHMe
Me
H
and enantiomer
Tolamolol to·lam·o·lol(RS)-4-[2-(2-Hydroxy-3-o-tolyloxypropylamino)ethoxy]benzamide;C19H24N2O4; 38103-61-6Tolamolol Hydrochloride 51599-37-2Beta-adrenoceptor antagonist
ON O
H2N
O
H OH
Me
H
and enantiomer
�Tolazamide tol·ä·za·mïd1-(Perhydroazepin-1-yl)-3-p-tolylsulfonylurea; C14H21N3O3S; 1156-19-0;TOLANASE
Hypoglycaemic
SNH
OOO
Me
NH
N
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4-118
Tolazoline tol·ä·zö·lën2-Benzyl-2-imidazoline; C10H12N2; 59-98-3Tolazoline Hydrochloride 59-97-2Vasodilator
HN
N
�Tolbutamide tol·bü·ta·mïd1-Butyl-3-tosylurea; C12H18N2O3S; 64-77-7; RASTINON
Hypoglycaemic
NS
OO
Me
NHBun
O
H
Tolcapone tol·ka·pön3,4-Dihydroxy-5-nitrophenyl(p-tolylphenyl)methanone; C14H11NO5; 134308-13-7; TASMAR
Catechol-O-methyl transferase inhibitor; antiparkinsonian
HO
HO
O
NO2
Me
Toldimfos tol·dim·fos4-Dimethylamino-o-tolylphosphinic acid; C9H14NO2P; 57808-64-7; CLOTAM
Toldimfos Sodium 5787-63-3; ̈ FOSTON
Phosphorus source
P
O
H
Me
NMe2
OH
Tolfenamic Acid tol·fe·nam·ikN-(3-Chloro-o-tolyl)anthranilic acid; C14H12ClNO2; 13710-19-5; CLOTAM;¨TOLFEDINE
Analgesic; anti-inflammatory
NH
Me
Cl
COOH
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4-119
Tolgabide tol·ga·bïd(E)-4-(4¢,5-Dichloro-2-hydroxy-3-methylbenzhydrylideneamino)-butyramide; C18H18Cl2N2O2; 86914-11-6; SL 81·0142-00Anticonvulsant
N CONH2
OH
Me
Cl
Cl
Tolmesoxide tol·me·soks·ïd4,5-Dimethyoxy-o-tolyl methyl sulfoxide; C10H14O3S; 38452-29-8Vasodilator
SMeO
Me
OMe
MeO
Tolmetin tol·me·tin1-Methyl-5-p-toluoylpyrrole-2-acetic acid; C15H15NO3; 426171-23-3Tolmetin Sodium 35711-34-3; TOLECTIN
Analgesic; anti-inflammatory
NCOOH
Me
O Me
�Tolnaftate tol·naf·tätO-2-Naphthyl N-methyl-m-tolylthiocarbamate; C19H17NOS; 2398-96-1;MYCIL*; TINADERM
Antifungal
O
S
N
Me
Me
Tolpentamide tol·pen·ta·mïd1-Cyclopentyl-3-tosylurea; C13H18N2O3S; 1027-87-8Hypoglycaemic
NH
SOO
NH
O
Me
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4-120
Tolperisone tol·pe·ri·sön(RS)-2,4¢-Dimethyl-3-piperidinopropiophenone; C16H23NO; 728-88-1Skeletal muscle relaxant
N
Me
O
H Me
and enantiomer
�Tolpiprazole1-[2-(5-Methyl-1H-pyrazol-3-yl)ethyl]-4-m-tolylpiperazine; C17H24N4;420326-13-0
NHNN
NMe
Me
Tolpronine tol·prö·nën(RS)-1-(1,2,3,6-Tetrahydro-1-pyridyl)-3-o-tolyloxypropan-2-ol; C15H21NO2;97-57-4Analgesic
Me
O NH OH
and enantiomer
Tolpropamine tol·prö·pa·mën(RS)-Dimethyl(3-phenyl-3-p-tolylpropyl)amine; C18H23N; 5632-44-0Histamine H1-receptor antagonist
Me
NMe2H
and enantiomer
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4-121
Tolrestat tol·res·tatN-[6-Methoxy-5-trifluoromethyl-1-naphthyl(thiocarbonyl)]-N-methyl-glycine; C16H14F3NO3S; 82964-04-3; AY-27773Aldose reductase inhibitor
N COOH
MeO
F3C
S
Me
Tolterodine tol·te·rö·dën(R)-2-[3-(Di-isopropylamino)-1-phenylpropyl]-p-cresol; C22H31O;124937-51-5Tolterodine Tartrate DETRUSITOL
Acetylcholine muscarinic receptor antagonist
NPr i2
H
OH
Me
Toltrazuril tol·tra·zûr·ril1-Methyl-3-{4-[4-(trifluoromethylthio)phenoxy]-m-tolyl}-1,3,5-triazinane-2,4,6-trione; C18H14F3N3O4S; 69004-03-1; ̈ BAYCOX
Coccidiostat (veterinary)
O
SF3C
Me
N
N
NH
O
OO
Me
Tolycaine tol·ë·känMethyl 2-diethylaminoacetamido-m-toluate; C15H22N2O3; 3886-58-6Tolycaine Hydrochloride 7210-92-6Local anaesthetic
NHMeOOC
O
NEt2
Me
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4-122
Tonabersat to·nab·er·satN-[(3S,4S)-6-Acetyl-3-hydroxy-2,2-dimethylchroman-4-yl]-3-chloro-4-fluorobenzamide; C20H19ClFNO4; 175013-84-0; SB-220453Treatment of migraine
O Me
Me
O NH
F
H3C
O
Cl
OH
Topiramate to·pï·ra·mät2,3:4,5-Di-O-(isopropylidene)-b-D-fructopyranose sulfamate; C12H21NO8S;97240-79-4; TOPAMAX
Anticonvulsant
O
O
O O
O
O NH2S
OO
Me
Me
Me
Me
Topotecan to·po·te·kan(S)-10-Dimethylaminomethyl-4-ethyl-4,9-dihydroxy-1H-pyrano[3¢,4¢:6,7]-indolizino[1,2-b]quinoline-3,14(4H,12H)-dione; C23H23N3O5; 123948-87-8;SK&F-104864Topotecan Hydrochloride 119413-54-6; HYCAMTIN
DNA topoisomerase I inhibitor; antineoplastic
N
N OHO
NMe2 O
OOHEt
Torasemide tor·ra·se·mïd1-Isopropyl-3-(4-m-toluidinopyridine-3-sulfonyl)urea; C16H20N4O3S;56211-40-6; TOREM
Torasemide Sodium 72810-59-4Diuretic
O OS
N
N
NHPr i
ONHMe
H
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Toremifene tor·re·mi·fën(Z)-2-[4-(4-Chloro-1,2-diphenylbut-1-enyl)phenoxy]ethyldimethylamine;C26H28ClNO; 89778-26-7; FARESTON
Antioestrogen
ONMe2
Cl
Tosactide (octacosactrin) to·sak·tïd[25-Aspartic acid,26-alanine,27-glycine]corticotrophin-(1-28)-octacosapeptide; C150H230N44O38S; 47931-80-6Corticotrophic peptide
Ser-Tyr-Ser-Met-Glu-His-Phe-Arg-Trp-Gly-Lys-Pro-Val-Gly-
Lys-Lys-Arg-Arg-Pro-Val-Lys-Val-Tyr-Pro-Asp-Ala-Gly-Glu
Tosylchloramide Sodium (chloramine) tö·sïl·klor·ra·mïd sö·dë·umN-Chlorotoluene-p-sulfonamide trihydrate, sodium salt; chloramine-T(USAN); 127-65-1
O OS
N
MeNa
ClH2O,3
Tracazolate tra·kaz·ö·lätEthyl 4-butylamino-1-ethyl-6-methyl-1H-pyrazolo[3,4-b]pyridine-5-car-boxylate; C16H24N4O2; 41094-88-6; ICI 136753Anxiolytic
NNN
Et
NHBun
Me
EtOOC
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Tramadol tra·ma·dol(±)-cis-2-Dimethylaminomethyl-1-(3-methoxyphenyl)cyclohexanol;C16H25NO2; 27203-92-5Tramadol Hydrochloride 36282-47-0; TRAMAKE; ZAMADOL; ZYDOL
Analgesic
MeO
OH
Me2N
H
and enantiomer
Tramazoline tra·mä·zö·lën2-Imidazolin-2-yl(5,6,7,8-tetrahydro-1-naphthyl)amine; C13H17N3;1082-57-1Tramazoline Hydrochloride 3715-90-0; DEXA-RHINASPRAY*Alpha-adrenoceptor agonist
N
N
NH H
Trandolapril tran·do·la·pril(2S,3aR,7aS)-1-{N-[(S)-1-Ethoxycarbonyl-3-phenylpropyl]-L-alanyl}-perhydroindole-2-carboxylic acid; C24H34N2O5; 87679-37-6; GOPTEN; ODRIK
Angiotensin-converting enzyme inhibitor
N
HN
O
H Me
H COOH
HEtOOCH
H
�Tranexamic Acid tran·eks·a·miktrans-4-Aminomethylcyclohexanecarboxylic acid; C8H15NO2; 1197-18-8;CYKLOKAPRON
Antifibrinolytic
COOHH
H
H2N
and enantiomer
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Tranylcypromine tra·nïl·sï·prö·mëntrans-2-Phenylcyclopropylamine; (C9H11N)2; 155-09-9�Tranylcypromine Sulphate 13492-01-8; PARNATE; PARSTELIN*Monoamine oxidase inhibitor
NH2 2
,H2SO4
and enantiomer
Trastuzumab tra·stü·zoo·mabImmunoglobulin G 1 (human–mouse monoclonal rhuMab HER2g1-chainantihuman p185c-erbB2 receptor), disulfide with human–mouse monoclonalrhuMab HER2-light chain, dimer; 180288-69-1
Immunomodulator
Trazodone tra·zö·dön2-[3-(4-m-Chlorophenylpiperazin-1-yl)propyl]-1,2,4-triazolo[4,3-a]pyridin-3(2H)-one; C19H22ClN5O; 19794-93�Trazodone Hydrochloride 25332-39-2; MOLIPAXIN
Antidepressant
N
N
N
ON
N Cl
Trenbolone tren·bo·lön17b-Hydroxyestra-4,9,11-trien-3-one; C18H22O2; 10161-33-8Trenbolone Acetate 10161-34-9; ̈ FINAJET
Anabolic steroid; androgen
O
Me
H
H
OH
H
Treosulfan trë·ö·sul·fanL-Threitol 1,4-dimethanesulfonate; C6H14N8S2; 299-75-2Cytotoxic
OHH
HHO
OSO2Me
OSO2Me
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Tresperimus tre·spe·ri·mus[(6-Guanidinohexyl)carbamoyl]methylN-{4-[(3-aminopropyl)amino]butyl}carbamate; C17H37N7O3; 160677-67-8;LF 08-0299Immunosuppressant
NNH
OO
NHNH
O
H2N
NH
HH2N
�Tretamine2,4,6-Tri(aziridin-1-yl)-1,3,5-triazine; triethanomelamine; triethylenemelamine; TEM; C9H12N6; 51-18-3
N
N
N
NN
N
�Trethinium Tosilate2-Ethyl-1,2,3,4-tetrahydro-2-methylisoquinolinium p-toluenesulfonate;C19H25NO3S; 1748-43-2
NEt
Me
+
Me
SO3_
�Tretinoin tre·tin·ö·in(1) 15-Apo-b-caroten-15-oic acid; (2) 3,7-dimethyl-9-(2,6,6-trimethylcyclo-hex-1-enyl)nona-2,4,6,8-all-trans-tetraenoic acid; (3) all-trans-retinoic acid;C20H28O2; 302-79-4; RETIN-A; RETINOVA; VESANOID
Treatment of acne
COOHMe Me
Me
MeMe
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�Triacetin trï·a·së·tinPropane-1,2,3-triyl triacetate; C9H14O6; 102-76-1Antifungal
H3C O O
O
O
O
CH3
CH3
O
Triacetyloleandomycin see Troleandomycin
�Triamcinolone trï·am·sin·o·lön9a-Fluoro-11b,16a,17a,21-tetrahydroxypregna-1,4-diene-3,20-dione;124-94-7Corticosteroid
Me
H
HMe
O
O
HOOH
F
OHOH
�Triamcinolone Acetonide9a-Fluoro-11b,21-dihydroxy-16a,17a-isopropylidenedioxy-pregna-1,4-diene-3,20-dione; C21H27FO6; 76-25-5; ADCORTYL; AUDICORT*; AURECORT*;KENALOG; LEDERCORT; NYSTADERMAL*; ̈ PANALOG*; PEVARYL-TC*; TRI-ADCORTYL*;¨VETALOG TOPICAL
Corticosteroid
Me
H
HMe
O
O
HOOH
F
O
O Me
Me
Triamcinolone Hexacetonide9a-Fluoro-11b-hydroxy-16a,17a-isopropylidenedioxy-3,20-dioxopregna-1,4-diene-21-yl 3,3-dimethylbutyrate; C30H41FO7; 5611-51-8; LEDERSPAN*Corticosteroid
Me
H
HMe
O
O
HOO
F
O
Me
O Me
MeO Me
Me
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�Triamterene trï·am·te·rën6-Phenylpteridine-2,4,7-triamine; C12H11N7; 396-01-0; DYAZIDE*; DYTAC;DYTIDE*; FRUSENE*; KALSPARE*; TRIAMAXCO*; TRIAMCO*Diuretic
N
N N
N
NH2
NH2
H2N
�TriaziquoneTri(aziridin-1-yl)-1,4-benzoquinone; C12H13N3O2; 68-76-80
N
O
N
NO
�Triazolam tri·ä·zö·lam8-Chloro-6-(2-chlorophenyl)-1-methyl-4H-[1,2,4]triazolo[4,3-a]-[1,4]benzodiazepine; C17H12Cl2N4; 28911-01-5Hypnotic
N
N
NN
Cl
Cl
Me
�Tribavirin trï·ba·vîr·rin1-b-D-Ribofuranosyl-1H-1,2,4-triazole-3-carboxamide; ribavirin (pINN;USAN); C8H12N4O5; 36791-04-5; VIRAZID
Antiviral
N
NN
OH
HO
OH
O
H2N
O
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Tribromsalan trï·brom·sa·lan3,4¢,5-Tribromosalicylanilide; C13H8Br3NO2; 87-10-5Anthelmintic
N
BrO
Br
Br
OH
H
Trichlormethine (trimustine) trï·klor·me·thënTris(2-chloroethyl)amine; C6H12Cl3N; 555-77-1Cytotoxic
NClCl
Cl
Triclabendazole trï·kla·ben·da·zôl5-Chloro-6-(2,3-dichlorophenoxy)-2-(methylthio)-1H-benzimidazole;C14H9Cl3N2OS; 68786-66-3; ̈ COMBINEX*; ̈ FASINEX*Antibacterial (veterinary)
O
Cl
N
N
Cl
Cl
SMe
H
Triclofenol Piperazine trï·klö·fë·nol pi·pe·ra·zënPiperazine bis(2,4,5-trichlorophenoxide); C16H16Cl6N2; 5714-82-9Anthelmintic
OH
Cl
Cl
ClHN
NH•
2
Triclofos trï·klö·fos2,2,2-Trichloroethyl dihydrogen phosphate; C2H4Cl3O4P; 306-52-5�Triclofos Sodium 7246-20-0Hypnotic
P
O
OH
OClCl
ClOH
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Triclosan trï·klö·san5-Chloro-2-(2,4-dichlorophenoxy)phenol; C12H7Cl3O2; 3380-34-5; AQUASEPT;MANUSEPT; OILATUM PLUS*; STER-ZAC LIQUID; TRICLOSEPT
Antiseptic
O
Cl
OHCl
Cl
�Tricyclamol Chloride(RS)-1-(3-Cyclohexyl-3-hydroxy-3-phenylpropyl)-1-methylpyrrolidiniumchloride; C20H32ClNO; 3818-88-0
NOH
Me
+
Cl_
and enantiomer
Tridihexethyl Chloride trï·dï·heks·ë·thïl(RS)-(3-Cyclohexyl-3-hydroxy-3-phenylpropyl)triethylammonium chloride;C21H36ClNO; 125-99-5Anticholinergic
Cl_
and enantiomer
OHNEt3+
Trientine Dihydrochloride trï·en·tën2,2-Ethylenedi-iminobis(ethylamine) dihydrochloride; trien hydrochloride;C6H18N4·2HCl; 38260-01-4Chelating agent
H2NN
NNH2
H
H
,2HCl
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Trifluomeprazine tri·floo·o·me·pra·zën(RS)-Dimethyl[2-methyl-3-(2-trifluoromethylphenothiazin-10-yl)propyl]amine; C19H21F3N2S; 2622-37-9▼Trifluomeprazine MaleateTranquilliser (veterinary)
N
S
NMe2
CF3
H Me
and enantiomer
Trifluoperazine trï·floo·ö·pe·ra·zën10-[3-(4-Methylpiperazin-1-yl)propyl]-2-trifluoromethylphenothiazine;C21H24F3N3S; 117-89-5�Trifluoperazine Hydrochloride 440-17-5; PARSTELIN*; STELAZINE
Antipsychotic
N
S
N
CF3
NMe
�Trifluperidol4¢-Fluoro-4-[4-hydroxy-4-(3-trifluoromethylphenyl)piperidino]butyro-phenone; C22H23F4NO2; 749-13-3
N
OH
F3C O
F
Triflupromazine (fluopromazine) trï·floo·prö·ma·zënDimethyl[3-(2-trifluoromethylphenothiazin-10-yl)propyl]amine;C18H19F3N2S; 146-54-3Antipsychotic
N
S
NMe2
CF3
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�Triflusal trï·floo·salO-Acetyl-4-(trifluoromethyl)salicylic acid; C10H7F3O4; 322-79-2
Treatment of thromboembolismCOOH
OAcF3C
Trifosmin tri·fos·minTris(3-methoxypropyl)phosphine; C12H27O3P; 83622-85-9Diagnostic agent
P OMe
OMe
MeO
Trihexyphenidyl/Benzhexol trï·heks·ë·fe·ni·dïl/benz·heks·ol(RS)-1-Cyclohexyl-1-phenyl-3-piperidinopropan-1-ol; C20H31NO; 144-11-6�Trihexyphenidyl Hydrochloride/Benzhexol Hydrochloride 52-49-3;ARTANE; BENTEX; BROFLEX
Anticholinergic
NOH
and enantiomer
Trilostane trï·lö·stän4a,5a-Epoxy-17b-hydroxy-3-oxoandrostane-2a-carbonitrile; C20H27NO3;13647-35-3; MODRENAL
Adrenocortical suppressant
Me
Me
H
H H
NC
OO
OH
H
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Trimazosin trï·mä·zö·sin2-Hydroxy-2-methylpropyl 4-(4-amino-6,7,8-trimethoxyquinazolin-2-yl)piperazine-1-carboxylate; C20H29N5O6; 35795-16-5Trimazosin Hydrochloride 35795-17-6; 53746-46-6 (monohydrate);CP-19106-1Alpha-adrenoceptor antagonist
N
N
N
N OMe
MeO
MeO
OMe
NH2
O
HO Me
Trimebutine trï·me·bü·tën(RS)-2-Dimethylamino-2-phenylbutyl 3,4,5-trimethoxybenzoate;C22H29NO5; 39133-31-8Antispasmodic
O CH3
OMe
MeO
MeO
O NMe2
and enantiomer
Trimegestone tri·me·jes·tön17b-[(S)-2-Hydroxypropionyl]-17a-methylestra-4,9-dien-3-one; C22H30O3;74513-62-5; RU27 987Progestogen; hormone replacement therapy
O
H
Me
H
Me
CH3
OHHO
Trimeperidine trï·me·pe·ri·dën1,2,5-Trimethyl-4-phenyl-4-piperidyl propionate; C17H25NO2; 64-39-1Opioid analgesic
NMe
O
Me
Me
CH3
O
***
mixture of 8 stereoisomers
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Trimeprazine see Alimemazine
�Trimetaphan Camsilate trï·me·ta·fan kam·si·lät(1) (+)-1,3-Dibenzylperhydro-2-oxothieno[1¢,2¢:1,2]thieno[3,4-d]imidazol-5-ium (S)-2-oxobornane-10-sulfonate; (2) 4,6-dibenzyl-4,6-diaza-1-thioniatricyclo[6.3.0.03,7]undecan-5-one 2-oxobornane-10-sulfonate;C32H40N2O5S2; 68-91-7Ganglion blocker
S
N
N
O
+
O
MeMeCH2SO3
_
mixture of cationic isomers
Trimetazidine trï·me·ta·zi·dën1-(2,3,4-Trimethoxybenzyl)piperazine; C14H22N2O3; 5011-34-7Trimetazidine Hydrochloride 13171-25-0Vasodilator
MeO
N
NH
OMe
MeO
�Trimethadione (troxidone)3,5,5-Trimethyl-1,3-oxazolidine-2,4-dione; C6H9NO3; 127-48-0
N
O O
O
Me
Me
Me
�Trimethidinium Methosulphate1,3,8,8-Tetramethyl-3-[3-(trimethylammonio)propyl]-3-azoniabicyclo[3.2.1]octane bis(methylsulfate); C19H42N2O8S2;7009-82-7
+N
Me
MeMe
NMe3
Me
H
+ CH3SO3_
2
and enantiomer
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�Trimethoprim trï·me·thö·prim5-(3,4,5-Trimethoxybenzyl)pyrimidine-2,4-diyldiamine; C14H18N4O3;738-70-5; BACTRIM*; ̈ BIMOTRIM*; ̈ BORGAL*; CHEMOTRIM* ̈ DELVOPRIM;¨DUPHATRIM*; ̈ EQUITRIM*; FECTRIM; IPRAL; LARATRIM*; ̈ LEOTROX*; MONOTRIM;¨NORODINE*; POLYTRIM*; ̈ PORSYN*; ̈ SCORPRIN*; SEPTRIN*; ̈ STRINACIN*;¨ SULFATRIM*; ̈ SYNUTRIM*; SYRAPRIM; TIEMPE; ̈ TRIBRISSEN*; ̈ TRIMABAC*;¨TRIMEDIAZINE*; ̈ TRIMEDOXINE*; TRIMOPAN; ̈ TRINACOL*; ̈ TRIVETRIN*;¨UNIPRIM*; ̈ VENTIPULMIN TMP/S*Antibacterial
N
N
OMe
MeO
MeO
H2N NH2
Trimetrexate trï·me·treks·ät5-Methyl-6-(3,4,5-trimethoxyanilinomethyl)quinazolin-2,4-diyldiamine;C19H23N5O3; 52128-35-5; NEUTREXIN
Cytotoxic
N
N
N
H2N
NH2 Me
OMe
OMe
OMeH
Trimipramine trï·mi·pra·mën(RS)-Dimethyl[3-(10,11-dihydro-5H-dibenz[b,f]azepin-5-yl)-2-methylpropyl]amine; C20H26N2; 739-71-9�Trimipramine Maleate 521-78-8; SURMONTIL
Antidepressant
N
NMe2H Me
and enantiomer
Trimustine see Trichlormethine
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�Triparanol(RS)-2-(4-Chlorophenyl)-1-[4-(2-diethylaminoethoxy)phenyl]-1-p-tolylethanol; C27H32ClNO2; 78-41-10
OH
OEt2N
Me
Cl
and enantiomer
�Tripelennamine trï·pe·len·a·mën2-[Benzyl(2-pyridyl)amino]ethyldimethylamine; C16H21N3; 91-81-6;¨DEXACOMPLEX*Histamine H1-receptor antagonist
NNMe2
N
Triprolidine trï·pro·li·dën(E)-2-[3-(Pyrrolidin-1-yl)-1-p-tolylprop-1-enyl]pyridine; C19H22N2; 486-12-4�Triprolidine Hydrochloride 6138-79-0; ACTIFED*;PRO-ACTIDIL; SUDAFED*Histamine H1-receptor antagonist
NH
Me
N
Triptorelin trip·tö·rë·lin[6-D-Tryptophan] luteinising hormone-releasing factor; C64H82N18O13;57773-63-4; DECAPEPTYL
Gonadorelin analogue
<Glu–His–Trp–Ser–Tyr–D-Trp–Leu–Arg
Pro–Gly–NH2
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Troglitazone trö·gli·ta·zönall-rac-5-[4-(6-Hydroxy-2,5,7,8-tetramethylchroman-2-ylmethoxy)benzyl]-1,3-thiazolidine-2,4-dione; C24H27NO5S; 97322-87-7; ROMOZIN
Hypoglycaemic
*Me
HO
Me
Me
MeO
O
NHS
O
O
*
mixture of 4 stereoisomers
Troleandomycin (triacetyloleandomycin) trö·lë·an·dö·mï·sin(2R,3S,4R,5S,6S,8R,10R,11S,12R,13R)-11-Acetoxy-3-(4-O-acetyl-2,6-dideoxy-3-O-methyl-a-L-arabino-hexopyranosyloxy)-5-(2-O-acetyl-3,4,6-trideoxy-3-dimethylamino-b-D-xylo-hexopyranosyloxy)-8,8-epoxymethano-2,4,6,10,12,13-hexamethyl-9-oxotetradecan-13-olide; C41H67NO15; 2751-09-9Antibiotic
MeO
O
O
O
OH
Me
NMe2
O
Me
MeO
Me
AcO
MeMe
O
Me
AcO
OMe
O
�Trolnitrate PhosphateDi[tris(2-nitratoethyl)ammonium] hydrogen phosphate; C6H12N4O9,2H3PO4; 588-42-1
NONO2O2NO
O2NOH3PO4,2
�Trometamol trö·me·ta·mol2-Amino-2-hydroxymethylpropane-1,3-diol; tromethamine (USAN);C4H11NO3; 77-86-1; component of several proprietary preparationsAlkalinising agent
OH
OHH2NHO
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Tropanserin trö·pan·ser·rin(8S)-Tropan-3-yl 3,5-dimethylbenzoate; C17H23NO2; 85181-40-4Tropanserin Hydrochloride 85181-38-0; MDL 72422 A5HT2-serotonin receptor antagonist
NMe
O
O
Me
Me
�Tropicamide trö·pi·ka·mïd(RS)-N-Ethyl-N-(4-pyridylmethyl)tropamide; C17H20N2O2; 1508-75-4;MINIMS TROPICAMIDE; MYDRIACYL
Anticholinergic
N
N Et
O
CH2OHH
and enantiomer
Tropigline trö·pi·glën(E)-(1R,3r,5S)-3-(Methylmethacryloyloxy)tropane; C13H21NO2; 533-08-4Antiparkinsonian
N
O Me
O
Me
H
Me
Tropisetron trö·pi·se·tron(3r)-Tropan-3-yl indole-3-carboxylate; C17H20N2O2; 89565-68-4Tropisetron Hydrochloride 105826-92-4; NOVOBAN
Serotonin 5HT3-receptor antagonist
N
O
O
NH
Me
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4-139
Trospectomycin trö·spek·tö·mï·sin(2R,4aR,5aR,6S,7S,8R,9S,9aR,10aS)-2-Butyl-4a,7,9-trihydroxy-6,8-bis(methylamino)perhydropyrano[2,3-b][1,4]benzodioxin-4-one;C17H30N2O7; 88669-04-9; U-63,366Trospectomycin Sulphate 88851-61-0Antibacterial
O
O
O
O
BunH
HONHMe
OH
MeHN
HO
H
Trospium Chloride trö·spë·um klor·rïd(1) (3r)-3-(Hydroxydiphenylacetoxy)-8l5-spiro[8-azabicyclo[3.2.1]octane-8,1´-pyrrolidin]-8-ylium chloride; (2) 3a-hydroxyspiro[1aH-nortropane-8,1´-pyrrolidinium] chloride benzilate; C25H30ClNO3; 10405-02-4
Antispasmodic
N+
O
O
OH
Cl_
Troxerutin troks·ë·roo·tin(1) 5-Hydroxy-7-(2-hydroxyethoxy)-2-[3,4-bis(2-hydroxyethoxy)phenyl]-4-oxo-4H-chromen-3-yl rutinoside; (2) 3¢,4¢,7-tris[O-(2-hydroxyethyl)]rutin;C33H42O19; 7085-55-4Treatment of venous disorders
OHO
O
HOO
OHO
OHO
O
O
O
O
OHOH
OH
OHOH
HOMe
Troxidone see Trimethadione
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�Troxonium Tosilate (BAN)N,N,N-Triethyl-2-(3,4,5-trimethoxybenzoyloxy)ethylammonium p-toluenesulfonate; C25H37NO8S; 391-70-8
OMe
MeO
MeOO
NEt3
O+
Me
SO3_
Troxypyrrolium Tosilate (BAN) troks·ë·pi·rö·lë·umN-Ethyl-N-2-(3,4,5-trimethoxybenzoyloxy)ethylpyrrolidinium p-toluene-sulfonate; C25H35NO8S; 3612-98-4Hypotensive
+
Me
SO3_
O
OMeO
MeO
OMe
Et
N
�Trypsin trip·sinA protease obtained from the pancreas of mammals by the extraction andsubsequent activation of trypsinogen; 9002-07-7Enzyme
�Tuaminoheptane(RS)-1-Methylhexylamine; C7H17N; 123-82-0
H3C CH3
H NH2
and enantiomer
�Tubocurarine Chloride tü·bö·kûr·rar·rën7¢,12¢-Dihydroxy-6,6¢-dimethoxy-2,2¢,2¢-trimethyltubocuraranium chloridehydrochloride; C37H42Cl2N2O6; 57-94-3Neuromuscular blocker
ONMe
O
Me2N
CH2
MeO
OH
OMe
OH
Cl_
+
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Tucaresol tü·ka·re·sola-(2-Formyl-3-hydroxyphenoxy)-p-toluic acid; C15H12O5; 589CTreatment of sickle-cell anaemia
O
COOH
OH
CHO
Tulobuterol tü·lö·bü·te·rol(RS)-2-tert-Butylamino-1-o-chlorophenylethanol; C12H18ClNO; 41570-61-0;RESPACAL
Beta-adrenoceptor agonist
Cl
NHBu tH OH
and enantiomer
Tybamate tï·ba·mät(RS)-2-Methyl-2-propyltrimethylene butylcarbamate carbamate;C13H26N2O4; 4268-36-4Anxiolytic
H3C
H3C
O NHBun
O NH2
O
O
and enantiomer
Tyformin see Tiformin
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▼Tylosin tï·lö·sinA macrolide antibiotic derived from an actinomycete resembling Streptomycesfradiae; 1401-69-0; ̈ BILOSIN; ̈ TYLACARE ̈ TYLUVET
Tylosin Phosphate ̈ TYLAMIX; ̈ TYLAN; ̈ TYLASUL PREMIX*▼Tylosin Tartrate ̈ TYLAN SOLUBLE; ̈ TYLASUL SOLUBLE*
O
Me
OMeMeOHOOH
O
OH
HOMe
NMe2
Me
OH
O
Me
O Me
HO
O
O
Me
H
O
O
Et
H
O
tylosin A
Tyloxapol tï·loks·a·pol4-(1,1,3,3-Tetramethylbutyl)phenol polymer with ethylene oxide andformaldehyde; 25301-02-4Non-ionic surfactant
OR
C8H17
OR
C8H17 C8H17
OR
m
R = CH2CH2O OCH2CH2OH[ CH2CH2O]n
m < 6 n = 6-8
Tymazoline (BAN) tï·mä·zö·lën2-(2-Isopropyl-5-methylphenoxymethyl)-2-imidazoline; C14H20N2O;24243-97-8Alpha-adrenoceptor agonist
NH
HN
O
Pr i
Me
Tyrothricin tï·rö·thrï·sinA mixture of antimicrobial polypeptides, including gramicidin and tyroci-dine, produced by Bacillus brevis; 1404-88-2; ¨AUROID*; TYROZETS*Antibiotic
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Ubisindine ü·bi·sin·dën(1) (RS)-2-(2-Diethylaminoethyl)-3-phenylisoindolin-1-one; (2) (RS)-2-(2-diethylaminoethyl)-3-phenylphthalimidine; C20H24N2O; 26070-78-0Antiarrhythmic
NNEt2
O
H
and enantiomer
Upenazime ü·pen·a·zëm(E,E)-3,3¢-Dimethyl-3,3¢-(butane-1,4-diyldi-imino)bis(butan-2-one oxime);C14H30N4O2; 95268-62-5; HL91Diagnostic agent
HN
N
OH
Me
Me
MeMe
Me
Me
OH
N
NH
Uramustine ûr·ra·mus·tën5-[Bis(2-chloroethyl)amino]uracil; uracil mustard (USAN); C8H11ClN3O2;66-75-1Cytotoxic
NH
N
NCl
Cl
O
O
H
Urapidil ûr·rap·i·dil6-[3-(4-o-Methoxyphenylpiperazin-1-yl)propylamino]-1,3-dimethyluracil;C20H29N5O3; 34661-75-1; B66-256MAlpha-adrenoceptor antagonist
N
N
OMe
N
NMeMeN
O
OH
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Uredofos ûr·rë·dö·fosDiethyl 3-[2-(3-tosylureido)phenyl]-2-thioureidophosphonate;C19H25N4O6PS2; 52406-01-6; RH-32565; RH-565Anthelmintic
P
O
OEt
EtO
HN
HN
S
O
HNS
OO
NH
Me
�Urofollitropin (urofollitrophin) ûr·rö·fol·li·trö·pinA preparation of menopausal gonadotrophin extracted from human urine,but possessing negligible luteinising hormone (LH) activity; METRODIN;ORGAFOL; PERGOGREEN*Follicle-stimulating hormone
�Urokinase ûr·rö·kï·näzAn enzyme isolated from human urine that converts plasminogen to plasmin;EC 3.4.21.31; 9039-53-6; UKIDAN
Enzyme
Ursodeoxycholic Acid er·sö·dë·oks·ë·kö·lik3a,7b-Dihydroxy-5b-cholan-24-oic acid; C24H40O4; 128-13-2; COMBIDOL*;DESTOLIT; LITHOFALK*; URDOX; URSOFALK; URSOGAL
Dissolution of cholesterol gallstones
HOH
H H
Me
Me
H
COOH
H
MeH
OH
Utibapril ü·ti·ba·pril(S)-5-tert-Butyl-3-{N-[(S)-1-ethoxycarbonyl-3-phenylpropyl]-L-alanyl}-2,3-dihydro-1,3,4-thiadiazole-2-carboxylic acid; C22H31N3O5S;109683-61-6Angiotensin-converting enzyme inhibitor
HN
O COOHH
SN
NH
EtOOC MeH
Bu t
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Utibaprilat ü·ti·ba·pri·lat(2S)-5-tert-Butyl-3-{N-[(S)-1-carboxy-3-phenylpropyl]-L-alanyl}-2,3-dihydro-1,3,4-thiadiazole-2-carboxylic acid; C20H27N3O5S; 109683-79-6Angiotensin-converting enzyme inhibitor
HN
O COOHH
SN
NH
HOOC MeH
Bu t
Valaciclovir va·la·sï·klö·veer2-[(2-Amino-1,6-dihydro-6-oxo-9H-purin-9-yl)methoxy]ethyl L-valinate;C13H20N6O4; 124832-26-4Valaciclovir Hydrochloride 124832-27-5; VALTREX
Antiviral
HN
N
N
NH2N
O
Me
MeH NH2
O
O
O
Valconazole val·ko·na·zôl(RS)-2-(2,4-Dichlorophenoxy)-1-imidazol-1-yl-4,4-dimethylpentan-3-one;C16H18ClN2O2; 56097-80-4; BAY f 8751Antifungal
Cl
Cl
MeMe
O
Me
N
N
O
and enantiomer
�Valproic Acid val·prö·ik2-Propylpentanoic acid; C8H16O2; 99-66-1�Sodium Valproate 1069-66-5; CONVULEX; EPILIM
Anticonvulsant
H3C
H3C COOH
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Valsartan val·sar·tanN-Pentanoyl-N-[2¢-(lH-tetrazol-5-yl)biphenyl-4-ylmethyl]-L-valine;C24H29N5O3; 137862-53-4; DIOVAN
Angiotensin-II receptor antagonist; antihypertensive
N
NN
HN
H3C
Me
H COOH
O
MeN
Valspodar val·spö·dar1,11-Cyclo{L-alanyl-D-alanyl-N-methyl-L-leucyl-N-methyl-L-leucyl-N-methyl-L-valyl-[(2S,4R)-(6E)]-4-methyl-2-(methylamino)-3-oxo-octen-6-oyl-L-valyl-N-methylglycyl-N-methyl-L-leucyl-L-valyl-N-methyl-L-leucine}; C63H111N11O12;121584-18-7
Multidrug resistance inhibitor; antineoplastic
Me
Ala_D_Ala_MeLeu_MeLeu_MeVal_N_C_CO_Val_MeGly_MeLeu_Val_MeLeu
MeMeH
O
H
H
H
Vancomycin van·kö·mï·sinA glycopeptide antibiotic produced by certain strains of Streptomycesorientalis; C66H75Cl2N9O24; 1404-90-6�Vancomycin Hydrochloride 1404-93-9; VANCOCIN
Antibacterial
Me
NH
HN
NH
HN
NH
CH3
O O O
O O NHMeCH3
O
HN
HO OHOH
O O
O ClCl CH2OH
Me
NH2
HO
O O
OH
HO
O
OH
HOOC
H
H
HH
H
H
HH
CONH2
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Vapiprost va·pi·prost(1) (Z)-(1R,2R,3S,5S)-7-[5-(Biphenyl-4-ylmethoxy)-3-hydroxy-2-piperidinocyclopentyl]hept-4-enoic acid; (2) (Z)-(9S,11S,12R)-9-biphenyl-4-ylmethoxy-11-hydroxy-12-piperidino-(13—20)octanorprost-4-enoic acid;C30H39NO4; 85505-64-2; GR 32191Vapiprost Hydrochloride 87248-13-3; GR 32191BThromboxane A2-antagonist
O
H
H
COOH
N
HH
HO
Vecuronium Bromide ve·kûr·rö·në·um1-(3a,17b-Diacetoxy-2b-piperidino-5a-androstan-16b-yl)-1-methyl-piperidinium bromide; C34H57BrN2O4; 50700-72-6; NORCURON
Neuromuscular blocker
NN
AcO
Me
H
H
H
H
Me OAc
MeBr
_+
Vedaprofen vë·da·prö·fen(RS)-2-(4-Cyclohexyl-1-naphthyl)propionic acid; C19H22O2; 71109-09-6;CERM 10202; PM 150Anti-inflammatory (veterinary)
and enantiomer
COOH
H Me
Velaresol ve·la·re·sol5-(2-Formyl-3-hydroxyphenoxy)valeric acid; C12H14O5; 77858-21-0; 12CTreatment of sickle-cell anaemia; antineoplastic
O
OH
CHO
COOH
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�Velnacrine(RS)-9-Amino-1,2,3,4-tetrahydroacridin-1-ol; C13H14N2O; 104675-29-8Velnacrine Maleate 118909-22-1; HP029; P83 6029A
N
NH2 OHH
and enantiomer
Venlafaxine ven·la·faks·ën(RS)-1-(2-Dimethylamino-1-p-methoxyphenylethyl)cyclohexanol;C17H27NO2; 93413-69-5Venlafaxine Hydrochloride 99300-78-4; EFEXOR
Antidepressant
NMe2
MeO
OH
H
and enantiomer
Verapamil ve·ra·pa·mil(RS)-5-[N-(3,4-Dimethoxyphenethyl)methylamino]-2-(3,4-dimethoxyphenyl)-2-isopropylvaleronitrile; C27H38N2O4; 52-53-9�Verapamil Hydrochloride 152-11-4; BERKATENS; CORDILOX; SECURON; TARKA;UNIVER
Antiarrhythmic
and enantiomer
N
MePr i CN
OMe
MeO
OMe
OMe
Verazide ve·ra·zïd2¢-Veratrylideneisonicotinohydrazide; C15H15N3O3; 93-47-0Antitubercular
NN
O
N
OMe
MeOH
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Verteporfin ver·te·por·finA 50:50 mixture of (24RS,3RS)-24,3-dihydro-23,24-bis(methoxycarbonyl)-12-[2-(methoxycarbonyl)ethyl]-3,7,13,18-tetramethyl-17-vinylbenzo[b]porphyrin-8-propionic acid and (24RS,3RS)-24,3-dihydro-23,24-bis(methoxycarbonyl)-8-[2-(methoxycarbonyl)ethyl]-3,7,13,18-tetramethyl-17-vinylbenzo[b]porphyrin-12-propionic acid; C41H42N4O8 (both components);129487-78-5
Photosensitizing agent
N HN
Me
H2CCOOMe
COOMeH
Me
NHMe
MeOOC
N
COOH
Me
N HN
Me
H2CCOOMe
COOMeH
Me
NHMe
HOOC
N
COOMe
Me
+
and enantiomer
and enantiomer
Vetrabutine ve·tra·bü·tën(RS)-Dimethyl-a-3-phenylpropylveratrylamine; C20H27NO2; 3735-45-3Vetrabutine Hydrochloride 5974-09-4; ̈ MONZALDON
Uterus relaxant
OMe
MeO
Me2N H
and enantiomer
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4-150
�Vidarabine vi·da·ra·bën9-b-D-Arabinofuranosyladenine; C10H13N5O4; 5536-17-4Antiviral
O
OH
HO
N
NN
N
NH2
HO
Vigabatrin vï·ga·ba·trin4-Aminohex-5-enoic acid; C6H11NO2; 60643-86-9; SABRIL
Anticonvulsant
COOHH2C
NH2H
and enantiomer
Viloxazine vi·loks·a·zën(RS)-2-(2-Ethoxyphenoxymethyl)morpholine; C13H19NO3; 46817-91-8Viloxazine Hydrochloride 35604-67-2; VIVALAN
Antidepressant
OO
HN
OEt
H
and enantiomer
Vinbarbital (vinbarbitone) vin·bar·bi·tal5-Ethyl-5-(1-methylbut-1-enyl)barbituric acid; C11H16N2O3; 125-42-8Hypnotic
H
NH
N OO
OMe
EtH3C
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Vinblastine vin·blas·tënAn alkaloid extracted from Vinca rosea; methyl (3aR,4R,5S,5aR,10bR,13aR)-4-acetoxy-3a-ethyl-9-[(5S,7S,9S)-5-ethyl-5-hydroxy-9-methoxycarbonyl-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoaza-cycloundecino[5,4-b]indol-9-yl]-5-hydroxy-8-methoxy-6-methyl-3a,4,5,5a, 6,11,12,13a-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate; vincaleukoblastine; C46H58N4O9; 865-21-4�Vinblastine Sulphate 143-67-9; VELBE
Cytotoxic
N
N
Et
OAc
H
MeO
MeH COOMe
HO
COOMe
Et
OHN
NH
Vincamine vin·ka·mënAn alkaloid obtained from Vinca minor; methyl (3a,14b,16a-14,15-dihydro-14-hydroxyeburnamenine-14-carboxylate; C21H26N2O3; 1617-90-9Vasodilator
NN
H
Et
HO
MeOOC
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Vincristine vin·kris·tënAn alkaloid extracted from Vinca rosea; methyl (3aR,4R,5S,5aR,10bR,13aR)-4-acetoxy-3a-ethyl-9-[(5S,7S,9S)-5-ethyl-5-hydroxy-9-methoxycarbonyl-1,4,5,6,7,8,9,10-octahydro-2H-3,7-methanoaza-cycloundecino[5,4-b]indol-9-yl]-6-formyl-5-hydroxy-8-methoxy-3a,4,5,5a, 6,11,12,13a-octahydro-1H-indolizino[8,1-cd]carbazole-5-carboxylate; 22-oxovincaleukoblastine; C46H56N4O10; 57-22-7�Vincristine Sulphate 2068-78-2; ONCOVIN
Cytotoxic
N
N
Et
OAc
H
MeOH COOMe
HO
COOMe
Et
OHN
NH
OHC
Vindesine vin·de·sën3-Carbamoyl-4-O-deacetyl-3-de(methoxycarbonyl)vincaleukoblastine;C43H55N5O7; 53643-48-4; ELDISINE
Cytotoxic
N
N
Et
OH
H
MeO
MeH CONH2
HO
COOMe
Et
OHN
NH
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Vinorelbine vin·or·rel·bën3¢,4¢-Didehydro-4¢-deoxy-8¢-norvincaleukoblastine; C45H54N4O8;71486-22-1Vinorelbine Tartrate 125317-39-7Antineoplastic
NH
MeOOC
N
N
Me
MeOH
EtH
H
COOMe
H
EtN
HO
OAc
Vinylbital (vinylbitone) vï·nïl·bi·tal(RS)-5-(1-Methylbutyl)-5-vinylbarbituric acid; C11H16N2O3; 2430-49-1Hypnotic
H
NH
N OO
OMe
H3CH2C
H
and enantiomer
�ViomycinAn antimicrobial peptide antibiotic produced by certain strains of Streptomy-ces griseus var· purpureus; tuberactinomycin B; C25H43N13O10; 32988-50-4
Viprostol vï·pros·tol(1) Methyl (5Z,13E)-(11R,16RS)-11,16-dihydroxy-9-oxo-16-vinylprosta-5,13-dienoate; (2) methyl (Z)-7-[(1R,2R,3R)-2-[(E)-(4RS)-butyl-4-hydroxyhexa-1,5-dienyl]-3-hydroxy-5-oxocyclopentyl]hept-5-enoate;C23H36O5; 73621-92-8; CL 115347Prostanoid vasodilator
H
HHO
COOMe
O
CH3HO
CH2
and epimer at C*
*
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Viprynium Embonate see Pyrvinium Pamoate
Virginiamycin ver·jin·e·a·mï·sinAntimicrobial substances produced by Streptomyces virginiae; certain compo-nents are identical with some constituents of mikamycin, ostreogrycin andpristinamycin; 11006-76-1; ̈ STAFAC
Antibiotic (veterinary)
Visnadine vis·na·dën(9R,10R)-10-Acetoxy-9,10-dihydro-8,8-dimethyl-2-oxo-2H,8H-pyrano[2,3-f]chromen-9-yl (R)-2-methylbutyrate; C21H24O7; 477-32-7Vasodilator
O
O
AcO
O
Me
Me
CH3OH MeO
Voriconazole vo·ri·kon·a·zôl(2R,3S)-2-(2,4-Difluorophenyl)-3-(5-fluoropyrimidin-4-yl)-1-(1,2,4-triazol-1-yl)butan-2-ol; C16H14N5F3O; 137234-62-9; UK-109,496Antifungal
N
NN
FH Me
F N N
F
OH
Vorozole vo·rö·zôl(S)-6-[4-Chloro-a-(1,2,4-triazol-1-yl)benzyl]-1-methyl-1H-benzotriazole;C16H13ClN6; 129731-10-8; R83842Aromatase (testosterone) inhibitor
N
NN
MeN
N
N
Cl
H
Votumumab vo·tü·mü·mabGamma immunoglobulin chain (human monoclonal antibody 88BV59 anti-tumour antigen); 148189-70-2Cytotoxic; diagnostic imaging agent and cytotoxic
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Warfarin wor·fa·rin(RS)-4-Hydroxy-3-(3-oxo-1-phenylbutyl)coumarin; C19H16O4; 81-81-2�Warfarin Sodium 129-06-6; MAREVAN
�Warfarin Sodium ClathrateAnticoagulant
O O
CH3
O
HOH
and enantiomer
Xaliproden za·li·prö·den1,2,3,6-Tetrahydro-1-[2-(2-naphthyl)ethyl]-4-(3-trifluoromethylphenyl)pyridine; C24H22F3N; 134354-02-8
Nootropic agent; treatment of neurodegenerative disease
N
CF3
Xamoterol za·mö·te·rol(RS)-N-[2-[2-Hydroxy-3-(4-hydroxyphenoxy)propylamino]ethyl]morpholine-4-carboxamide;C16H25N3O5; 81801-12-9Xamoterol Fumarate 73210-73-8; CORWIN
Beta-adrenoceptor agonist
HO
OHN
N N
OH O
O
H
H
and enantiomer
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Xantinol Nicotinate (xantinol nicotinate) zan·ti·nol ni·kö·ti·nät(RS)-7-{2-Hydroxy-3-[2-hydroxyethyl(methyl)amino]propyl}theophylline—nicotinic acid (1:1); C13H21N5O4,C6H5NO2; 437-74-1Vasodilator
MeN
N
N
N
O
O
Me
NOH
MeOHH
•N
COOH
and enantiomer
Xantocillin (xanthocillin) zan·tö·si·linAntibiotics obtained from the mycelium of Penicillium notatum (xantocillin Xis 2,3-di-isocyano-1,4-bis(4-hydroxyphenyl)buta-1,3-diene); C18H12N2O2;580-74-5Antibiotic
NC
HO OH
NC
Xenysalate ze·ni·sa·lät2-Diethylaminoethyl 2-hydroxybiphenyl-3-carboxylate; biphenamine(USAN); C19H23NO3;3572-52-9Treatment of seborrhoea
ONEt2
OOH
Xibornol zï·bor·nol6-[(1R,2S,4S)-Born-2-yl]-3,4-xylenol; C18H26O; 13741-18-9; 1BX; 1HP;CP3HAntibacterial
MeMe
Me
H
Me
Me
OH
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4-157
Xipamide zip·a·mïd4-Chloro-5-sulfamoylsalicylo-2¢,6¢-xylidide; C15H15ClN2O4S;14293-44-8; DIUREXAN
Antihypertensive; diuretic
H2N
O OS
N
OMe
MeOHCl
H
�Xylamide Tosilate(RS)-N-[2-(3-Methoxyphenoxy)propyl]-N-[2-(m-tolyl)acetimidoyl]ammonium p-toluenesulfonate; xylamidine tosylate(USAN); C26H32N2O5S; 6443-40-9
O
OMe
NH Me
NH
MeH
•Me
SO3H
and enantiomer
Xylazine zï·la·zënN-(5,6-Dihydro-4H-1,3-thiazin-2-yl)-2,6-xylidine; C12H16N2S;7361-61-7; ̈ ANASED; ̈ CHANAZINE; ̈ ROMPUN; ̈ VIRBAXYL
Analgesic
N
S
N
Me
MeH
�Xylitol zï·li·tolXylitol; C5H12O5; 87-99-0Pharmaceutical aid
H OH
HHO
OHH
OH
OH
![Page 721: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/721.jpg)
4-158
Xylometazoline zï·lö·me·täz·ö·lën2-(4-tert-Butyl-2,6-dimethylbenzyl)-2-imidazoline; C16H24N2; 526-36-3�Xylometazoline Hydrochloride 1218-35-5; OTRIVINE; OTRIVINE-ANTISTIN*;RYNACROM CO*Alpha-adrenoceptor agonist
H
N
NMe
Me Bu t
Zafirlukast za·feer·loo·kastCyclopentyl {3-[2-methoxy-4-(o-tolylsulfonylaminocarbonyl)benzyl]-1-methylindol-5-yl}carbamate; C31H33N3O6S; 107753-78-6; ACCOLATE
Leukotriene-receptor antagonist; antiasthmatic
MeO
O
O NH
NH
N
Me
Me
SOO
O
Zalcitabine zal·sï·ta·bën2¢,3¢-Dideoxycytidine; C9H13N3O3; 7481-89-2; HIVID
Antiviral
OHO
O
NH2
N
N
Zaleplon zal·e·plon3¢-(3-Cyanopyrazolo[1,5-a]pyrimidin-7-yl)-N-ethylacetanilide; C17H15N5O;151319-34-5; CL 284846; L846; LJC 10846; ZAL-846Sedative; hypnotic
NNN Et
NAc
NC
![Page 722: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/722.jpg)
4-159
Zaltidine zal·ti·dën2-{[4-(2-Methyl-1H-imidazol-4-yl)-1,3-thiazol-2-yl]}guanidine; C8H10N6S;85604-00-8Zaltidine Hydrochloride 90274-23-0 (2HCl); CP-57361-01Histamine H2-receptor antagonist
NH
N
N
SMe
N
NH2
H2N
Zanamivir za·na·mi·veer5-Acetamido-2,6-anhydro-3,4,5-trideoxy-4-guanidino-D-glycero-D-galacto-non-2-enonic acid; C12H20N4O7; 139110-80-8; GR 121167XAntiviral
OHO
NH2HN
COOH
NH
OHH
OHAcHN
Zaprinast za·pri·nast1,4-Dihydro-5-(2-propoxyphenyl)-1,2,3-triazolo[4,5-d]pyrimidin-7-one;C13H13N5O2; 37762-06-4; M&B 22948Antiallergic
N
N
HN
N
N
O
OCH3
H
Zatosetron za·tö·se·tron(3r)-5-Chloro-2,3-dihydro-2,2-dimethyl-N-tropan-3-ylbenzo[b]furan-7-carboxamide; C19H25ClN2O2; 123482-22-4Zatosetron Maleate 123482-23-5; LY277359Serotonin 5HT3-receptor antagonist
O
HN
MeN
Cl
O
MeMe
![Page 723: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/723.jpg)
4-160
Zeranol ze·ra·nol(3S,7R)-3,4,5,6,7,8,9,10,11,12-Decahydro-7,14,16-trihydroxy-3-methyl-1H-2-benzoxacyclotetradecin-1-one; C18H26O5; 26538-44-3Oestrogen
O
O H Me
H
OH
OH
HO
Zetidoline ze·tïd·o·len1-(3-Chlorophenyl)-3-[2-(3,3-dimethylazetidin-1-yl)ethyl]-2-imidazolidone;C16H22ClN3O; 51940-78-4Zetidoline Hydrochloride 74315-62-1; L 9308; DL-308-IT; MDL-308Antipsychotic
NNN
Me
MeO
Cl
�Zidovudine zï·do·vü·dën3¢-Azido-3¢-deoxythymidine; azidothymidine; AZT; C10H13N5O4;30516-87-1; COMBIVIR*; RETROVIR
Antiviral
O
N3
HOO
O
Me
N
HN
Zileuton zï·lü·tron(RS)-1-[1-(Benzo[b]thien-2-yl)ethyl]-1-hydroxyurea; C11H12N2O2S;111406-87-2; Abbott 64077Leukotriene synthesis inhibitor; 5-lipoxygenase inhibitor
and enantiomer
SN NH2
O
OH
H Me
![Page 724: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/724.jpg)
4-161
�Zimeldine(Z)-4-Bromo-g-(3-pyridyl)cinnamyldimethylamine; C16H17BrN2;56775-88-3
N
NMe2
HBr
Ziprasidone zï·pra·si·dön5-{2-[4-(1,2-Benzothiazol-3-yl)piperazin-1-yl]ethyl}-6-chloro-1,3-dihydroindol-2-one; C21H21ClN4OS; 146939-27-7; CP-88,059Dopamine-D2 and 5HT2-receptor antagonist; antipsychotic
NS
N
N
NH
O
Cl
Zofenopril zo·fe·nö·pril(4S)-1-[(2S)-3-(Benzoylthio)-2-methylpropionyl]-4-phenylthio-L-proline;C22H23NO4S2; 81872-10-8Zofenopril Calcium 81938-43-4; SQ 26,991Angiotensin-converting enzyme inhibitor
O COOHH
N
SH
O
Me
HS
Zolasartan zö·la·sar·tan1-{3-Bromo-2-[2-(1H-tetrazol-5-yl)phenyl]benzo[b]furan-5-ylmethyl}-2-butyl-4-chloro-1H-imidazole-5-carboxylic acid; C24H20BrClN6O3;145781-32-4; GR 117289CAntihypertensive; angiotensin II receptor antagonist
NH
N
NN
Br
Cl
O
N COOH
N
Bun
![Page 725: BP_BAN](https://reader034.fdocuments.us/reader034/viewer/2022052117/55cf98b5550346d033993ce6/html5/thumbnails/725.jpg)
4-162
Zolazepam zö·läz·e·pam4-(2-Fluorophenyl)-1,6,7,8-tetrahydro-1,3,8-trimethylpyrazolo[3,4-e][1,4]diazepin-7-one; C15H15FN4O; 31352-82-6Zolazepam Hydrochloride 33745-44-3; CI-716Sedative (veterinary)
NN
N
N
F
OMe
Me
Me
Zoledronic Acid zö·le·dro·nik1-Hydroxy-2-(imidazol-1-yl)ethane-1,1-diyldiphosphonic acid; C5H10N2O7P2;118072-93-8Inhibition of bone resorption
PHO
O
OH
C
OH
P OH
O
OH
NN
Zolmitriptan zol·mi·trip·tan(S)-4-{3-[2-(Dimethylamino)ethyl]indol-5-ylmethyl}-1,3-oxazolidin-2-one;C16H21N3O2; 139264-17-8; ZOMIG
5HT1D-Serotonin receptor agonist
O NH
O
HNMe2
HN
Zolpidem zol·pi·demN,N-Dimethyl-2-(6-methyl-2-p-tolylimidazo[1,2-a]pyridin-3-yl)acetamide;C19H21N3O; 82626-48-0Zolpidem Tartrate STILNOCT
Hypnotic
N
N
Me
O NMe2
Me
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4-163
Zomepirac zö·me·pi·rak5-(4-Chlorobenzoyl)-1,4-dimethylpyrrol-2-ylacetic acid; C15H14ClNO3;33369-31-2Zomepirac Sodium 64092-48-4Analgesic; anti-inflammatory
O
Cl
NCOOH
Me
Me
Zonisamide zo·ni·sa·mïd1-(1,2-Benzoxazol-3-yl)methanesulfonamide; C8H8N2O3S; 68291-97-4;CI-912; AD-810; PD-110843Anticonvulsant
NO
NH2S
OO
�Zopiclone zo·pi·klön(RS)-6-(5-Chloro-2-pyridyl)-6,7-dihydro-7-oxo-5H-pyrrolo[3,4-b]pyrazin-5-yl 4-methylpiperazine-1-carboxylate; C17H17ClN6O3; 43200-80-2; ZILEASE;ZIMOVANE
Hypnotic
N
N
N
O
NCl
O
N O
MeN
H
and enantiomer
Zopolrestat zö·pol·re·stat3,4-Dihydro-4-oxo-3-(5-trifluoromethyl-1,3-benzothiazol-2-ylmethyl)-phthalazin-1-ylacetic acid; C19H12F3N3O3S; 110703-94-1; CP-73,850Aldose reductase inhibitor; used in the treatment of diabetes
S
N
N
NCF3
O
COOH
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4-164
Zotepine zö·te·pën[2-(8-Chlorodibenzo[b,f]thiepin-10-yloxy)ethyl]dimethylamine;C18H18ClNOS; 26615-21-4
Antipyschotic
S
Cl
ONMe2
�Zoxazolamine5-Chloro-1,3-benzoxazol-2-ylamine; C7H5ClN2O; 61-80-3
O
NNH2
Cl
Zuclopenthixol zoo·klö·pen·thiks·ol(Z)-2-{4-[3-(2-Chloro-10H-dibenzo[b,e]thiin-10-ylidene)propyl]piperazin-1-yl}ethanol; Z-clopenthixol; C22H25ClN2OS; 53772-83-1�Zuclopenthixol Acetate CLOPIXOL ACCUPHASE
�Zuclopenthixol Decanoate CLOPIXOL INJECTION
�Zuclopenthixol Hydrochloride 633-59-0; CLOPIXOL TABLETS
Antipsychotic
N
NOH
H
Cl
S
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1
Names for ions and groupsSome substances for which British Approved Names have been established may beused in the form of salts or esters. The ions or groups involved may be of complexcomposition and it is then inconvenient to refer to them in systematic chemicalnomenclature. Shorter nonproprietary names for some such ions and groups havebeen devised or selected, and they are recommended for use with British ApprovedNames.
Recommended Recommended Chemical NameName Pronunciationacetonide a·se·to·nïd isopropylidene ether of a dihydric alcoholaceturate a·se·tûr·rät N-acetylglycinateamsonate am·so·nat 4,4¢-diaminostilbene-2,2¢-disulfonateaxetil aks·e·til l-acetoxyethylbesilate be·si·lät benzenesulfonatecamsilate kam·si·lät camphor-10-sulfonatecilexetil sï·leks·e·til (RS)-1-[(cyclohexyloxy)carbonyloxy]ethylcipionate si·pi·o·nät b-cyclopentylpropionateclosilate klö·si·lät 4-chlorobenzenesulfonatecromesilate krö·mes·i·lät 6,7-dihydroxycoumarin-4-methanesulfonateedisilate e·di·si·lät ethane-1,2-disulfonateembonate em·bo·nät 4,4¢-methylenebis(3-hydroxy-2-naphthoate)enanthate en·an·thät heptanoateerbumine er·bü·mën tert-butylamineesilate e·si·lät ethanesulfonateetabonate e·ta·bo·nät ethoxycarbonyloxygluceptate gloo·sep·tät glucoheptonateisethionate ï·se·thï·ö·nät 2-hydroxyethanesulfonatemegallate me·ga·lät 3,4,5-trimethoxybenzoatemesilate me·si·lät methanesulfonatemetilsulfate me·til·sul·fät methylsulfatemofetil mö·fe·til 2-(morpholino)ethylnapadisilate na·pa·dï·si·lät naphthalene-1,5-disulfonatenapsilate nap·si·lät naphthalene-2-sulfonatepivalate pi·va·lät trimethylacetatepivoxetil pi·voks·e·til 1-(methoxy-2-methylpropionyloxy)ethylpivoxil pi·voks·il (2,2-dimethyl-1-oxopropoxy)methylproxetil proks·e·til 1-[(isopropoxycarbonyl)oxylethylsuleptanate sü·lep·ta·nät sodium 7-[methyl(2-sulfonatomethyl)-
carbamoyl]heptanoylteoclate të·ö·klät 8-chlorotheophyllinatetosilate tö·si·lät toluene-4-sulfonatetroxundate troks·un·dät 3,6,9-trioxaundecanoatexinafoate zi·na·fö·ät 1-hydroxy-2-naphthoate
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1
Names for substance-combinations
In the prescribing and dispensing of compounded preparationscontaining two active ingredients, and for which the following namesare provided, the nominal amounts of the components per unit doseor per single-dose container are indicated where necessary in theform x/y where x and y are the respective amounts in milligrams of thecomponents in the order implied in the name. For oral liquidpreparations a unit dose is taken as 5 millilitres. For parenteralpreparations x and y are the nominal amounts in milligrams of thecomponents in the container.
ExamplesTablets containing 5 mg of amiloride hydrochloride and 50 mg ofhydrochlorothiazide are described as co-amilozide 5/50 tablets.An oral suspension containing 125 mg of amoxycillin trihydrate and632 mg of clavulanic acid (as the potassium salt) in 5 ml is describedas co-amoxiclav 125/62 oral suspension; an injection containing 500 mgand 100 mg respectively in 10 ml is described as co-amoxiclav 500/100injection.
�Co-amilofruse kö-a·mi·lö·früsAmiloride hydrochloride and frusemide in the proporations, byweight, 1 part to 8 parts respectively; ARIDIL; FRU-CO; FRUMIL;FRUSEMEK; LASORIDE Diuretic
�Co-amilozide kö-a·mi·lö·zidAmiloride hydrochloride and hydrochlorothiazide in theproportions, by weight, 1 part to 10 parts respectively; AMIL-CO;DELVAS; HYPERTANE; MODURET 25; MODURETIC; NORMETIC;THYAMILDiuretic
�Co-amoxiclav kö-a·moks·i·klavAmoxycillin (as the trihydrate or as the sodium salt) andclavulanic acid (as potassium clavulanate); the proportions areexpressed in the form x/y where x and y are the strength inmilligrams of amoxycillin and clavulanic acid respectively;AUGMENTIN; ¨ SYNULOXAntibacterial
�Co-beneldopa kö-ben·el·dö·paBenserazide (as the hydrochloride) and levodopa in theproportions, by weight, 1 part to 4 parts respectively; MADOPARTreatment of the Parkinsonian syndrome
�Co-careldopa kö-ka·rel·dö·paCarbidopa and levodopa; the proportions are expressed in theform x/y, where x and y are the strengths in milligrams ofcarbidopa and levodopa respectively; SINEMETAntiparkinsonian
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2�Co-codamol kö-kö·da·mol
Codeine phosphate and paracetamol; the proportions areexpressed in theform x/y where x and y are the strengths in milligrams of codeinephosphate and paracetamol respectively; MEDOCODENE;PANADEINE; PARACODOL; PARAKE; PERSOMNIA; TYLEXAnalgesic
�Co-codaprin kö-kö·da·prinCodeine phosphate and aspirin in the proportions, by weight, 1part to50 parts respectivelyAnalgesic
Co-cyprindiol kö-sï·prin·dï·olCyproterone acetate and ethinyloestradiol in the proportions byweight,2000 parts to 35 parts, respectively; DIANETTETreatment of acne
�Co-danthramer kö-dan·thra·merDanthron and poloxamer 188; the proportions are expressed inthe form x/y, where x and y are the strengths in milligrams ofdanthron and poloxamerrespectively; AILAX; CODALAX; DORBANEXStimulant laxative
�Co-danthrusate kö-dan·throo·sätDanthron and docusate sodium in the proportions by weight, 5parts to 6 parts respectively; CAPSUVAC; NORMAXStimulant laxative
�Co-dydramol kö-dï·dra·molDihydrocodeine tartrate and paracetamol in the proportions, byweight,1 part to 50 parts respectively; GALAKE; PARAMOLAnalgesic
Co-fluampicil kö-floo·am·pi·silFlucloxacillin and ampicillin in equal proportions by weight; FLU-AMP; MAGNAPENAntibacterial
Co-flumactone kö-floo·mak·tönHydroflumethiazide and spironolactone in equal proportions byweight; ALDACTIDEDiuretic
Co-magaldrox kö-ma·gal·droksMagnesium and aluminium hydroxide; the proportions areexpressed in the form x/y where x and y are the strengths inmilligrams per unit dose of magnsesium hydroxide and aluminiumhydroxide respectively; MAALOX; MUCOGELAntacid
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3Co-methiamol kö-me·thï·a·mol
DL-Methionine and paracetamol; the proportions are expressedin the form x/y where x and y are the strength in milligrams of DL-methionine and paracetamol respectively; PAMETON (co-methiamol250/500);PARADOTE (co-methiamol 100/500)Analgesic and antidote to hepatotoxicity
Co-phenotrope kö-fe·nö·tröpDiphenoxylate hydrochloride and atropine sulphate in theproportions, by weight, 100 parts to 1 part respectively; LOMOTIL;LOTHARINAntidiarrhoeal
Co-prenozide kö-pre·nö·zïdOxprenolol hydrochloride and cyclopenthiazide in theproportions, by weight, 640 parts to 1 part respectively; TRASIDREXBeta-adrenoceptor; antagonist; diuretic
�Co-proxamol kö-proks·a·molDextroproxyphene hydrochloride and paracetamol in theproportions, by weight, 1 part to 10 parts respectively;COSALGESTIC; DEXTROGESTIC; DISTALGESIC; PAXALGESICAnalgesic
Co-simalcite kö-sï·mal·sïtActivated dimethicone and hydrotalcite; the proportions areexpressed in the form x/y, where x and y are the strengths inmilligrams of activated dimethicone and hydrotalcite respectively;ALTACITE PLUSAntacid
�Co-tenidone kö-te·ni·dönAtenolol and chlorthalidone in the proportions, by weight, 4parts to 1 part respectively; TENORET 50; TENORETICBeta-adrenoceptor antagonist; diuretic
Co-tetroxazine kö-te·troks·a·zënTetroxoprim and sulphadiazine in the proportions, by weight, 2parts parts to 5 parts respectivelyAntibacterial
�Co-triamterzide kö-trï·am·ter·zïdTriamterene and hydrochlorothiazide in the proportions, byweight, 2 parts to 1 part respectively; DYAZIDE; TRIAMCODiuretic
Co-trifamole kö-tri·fa·mölTrimethoprim and sulphamoxole in the proportions, by weight, 1part to 5 parts respectivelyAntibacterial
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4�Co-trimazine kö-tri·ma·zën
Trimethoprim and sulphadiazine in the proportions, by weight; 1part to 5 parts respectively; ¨DELVOPRIM; ¨DUPHATRIM;¨EQUITRIM; ¨GEATRIM; ¨NORODINE; ¨ PORSYN; ¨ SCORPRIN;¨ STRINACIN II; ¨ SULFATRIM; ¨ SYNUTRIM; ¨TRIBRISSEN;¨TRIMBAC; ¨TRIMEDIAZINE; ¨TRIMEDOXINE; ¨TRINACOL;¨UNIPRIM; ¨ VENTIPULMINAntibacterial
�Co-trimoxazole kö-tri·moks·a·zölTrimethoprim and sulphamethoxazole in the proportions, byweight, 1 part to 5 parts; BACTRIM; CHEMOTRIM; COMOX;FECTRIM; LARATRIM; SEPTRIN; UCLAPRIMAntibacterial
Co-zidocapt kö-zï·dö·kaptHydrochlorothiazide and captopril in the proportions, by weight,1 part to 2 parts respectively; CAPOZIDE
Diuretic
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A.T.10 DihydrotachysterolABBOXAPAM OxazepamABELCET AmphotericinABIMASTEN-100 NifuroquineACCOLATE ZafirlukastACCUPRO QuinaprilACCURETIC QuinaprilACCUSITE Fluorouracil + AdrenalineACEPRIL CaptoprilACEZIDE CaptoprilACHROMYCIN TetracyclineACLACIN AclarubicinACNIDAZIL MiconazoleACP AcepromazineACTAL Alexitol SodiumACTHAR CorticotrophinACTIFED TriprolidineACTILYSE AlteplaseACTINAC Allantoin + ChloramphenicolACULAR KetorolacACUPAN NefopamADALAT NifedipineADCORTYL TriamcinoloneADCORTYL WITH
GRANEODIN GramicidinADENOCOR AdenosineADENOSCAN AdenosineADENYL Adenosine PhosphateADIFAX DexfenfluramineADIPINE NifedipineADIZEM DiltiazemADVIL IbuprofenAEROBEC BeclomethasoneAEROCROM Salbutamol + Cromoglycic AcidAEROLIN SalbutamolAERRANE IsofluraneAFRAZINE OxymetazolineAGAROL PhenolphthaleinAGRELIN Anagrelide
AGRICLENS Benzalkonium ChlorideAILAX Danthron + PoloxamerAIROMIR SalbutamolAKINETON BiperidenAKNEMIN MinocyclineALAMYCIN OxytetracyclineALBAC BacitracinALBADRY NovobiocinALBAMYCIN T TetracyclineALCOBON FlucytosineALCON PolymyxinALDACTIDE Co-flumactoneALDACTIDE Hydroflumethiazide +
SpironolactoneALDACTONE SpironolactoneALDOMET MethyldopaALDOMET INJECTION MethyldopateALEC PumactantALFA-D AlfacalcidolALGITEC Cimetidine + Alginic AcidALIMIX CisaprideALKERAN MelphalanALL SEASONS DiazinonALLBEE Pantothenic AcidALLEGRON NortriptylineALLER-EZE ClemastineALLER-EZE CLEAR TerfenadineALLVERM AlbendazoleALMODAN AmoxycillinALOMIDE LodoxamideALOPHEN Aloin + PhenolphthaleinALPHACEPT AlfaprostolALPHAPARIN CertoparinALPHLO TamsulosinALPHODITH DithranolALPHOSYL HC AllantoinALPHOSYL AllantoinALTACITE HydrotalciteALTACITE PLUS HydrotalciteALUDEX Amitraz
British Approved Names and Proprietary Names:Cross-reference index
Note Proprietary names may apply to a substance to which either a BAN or a BANM hasbeen given.
Proprietary names shown in ITALICS are for discontinued products.
Proprietary products consisting of two or more active ingredients may contain moreingredients than shown in this index. Hydrocortisone, hydrochlorthiazide and thiamine, forexample, are ingredients of so many products that it is impractical to show each proprietaryname.
Proprietary Name British Approved name Proprietary Name British Approved name
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Proprietary Name British Approved name Proprietary Name British Approved nameALUDROX SA Ambutonium BromideALUPENT OrciprenalineALVEDON ParacetamolALVERCOL AlverineALYRANE EnfluraneAMARYL GlimepirideAMBAXIN BacampicillinAMBISOME AmphotericinAMERICAN NUTRITION Pantothenic AcidAMERSCAN Medronic AcidAMETHOZOL Sulphathiazole + AmethocaineAMETOP AmethocaineAMFIPEN AmpicillinAMIAS CandesartanAMIKIN AmikacinAMIL-CO AmilorideAMIPAQUE MetrizamideAMNIVENT AminophyllineAMORAM AmoxycillinAMOXIL AmoxycillinAMOXINSOL AmoxycillinAMOXYPEN AmoxycillinAMPHOCIL AmphotericinAMPICAPS AmpicillinAMPICLOX Cloxacillin + AmpicillinAMPROL-PLUS Amprolium + EthopabateAMPROLMIX-UK EthopabateAMSIDINE AmsacrineAMYTAL AmylobarbitoneANABACT MetronidazoleANACAL Prednisolone + HexachlorophaneANADIN PARACETAMOL ParacetamolANAFEN IbuprofenANAFLEX PolynoxylinANAFRANIL ClomipramineANASED XylazineANDROCUR CyproteroneANDROJECT TestosteroneANDROPATCH TestosteroneANECTINE Suxamethonium ChlorideANEXATE FlumazenilANGETTES AspirinANGEZE Isosorbide MononitrateANGILOL PropranololANGIOGRAFIN Diatrizoic AcidANGIOPINE NifedipineANGIOZEM DiltiazemANGITATE Isosorbide MononitrateANGITIL DiltiazemANIVIT B CyanocobalaminANQUIL BenperidolANTABUSE DisulfiramANTEPSIN SucralfateANTHELPOR LevamisoleANTHISAN Mepyramine
ANTIPRESSAN AtenololANTIROBE ClindamycinANTRADERM DithranolANTRANOL DithranolANTURAN SulphinpyrazoneANUGESIC PramoxineAPPERTEX ClazurilAPRALAN ApramycinAPRESOLINE HydralazineAPRINOX BendrofluazideAPROVEL IrbesartanAPSIFEN IbuprofenAPSOLOL PropranololAPSOLOX OxprenololAQUAGARD DichlorvosAQUALINE Oxolinic AcidAQUASEPT TriclosanAQUATET OxytetracyclineAQUINOX Oxolinic AcidARAMINE MetaraminolAREDIA Pamidronic AcidARELIX PiretanideARICEPT DonepezilARIDIL FrusemideARIMIDEX AnastrozoleARLACEL Sorbitan SesquioleateARMADOSE LevamisoleARPICOLIN ProcyclidineARQUEL Meclofenamic AcidARRET LoperamideARTANE BenzhexolARTHROFEN IbuprofenARTHROTEC MisoprostolARTRACIN IndomethacinARVIN AncrodARYTHMOL PropafenoneASACOL MesalazineASCAPILLA CambendazoleASENDIS AmoxapineASMAVEN SalbutamolASMAVEN SalbutamolASPAV Papaveretum + Codeine + AspirinATARAX HydroxyzineATENSINE DiazepamATIVAN LorazepamATROCARE AtropineATROMID-S ClofibrateATROVENT Ipratropium BromideAUDAX Choline SalicylateAUDICORT TriamcinoloneAUGMENTIN Co-amoxiclavAUREOCORT Triamcinolone + ChlortetracyclineAUREOGRAN ChlortetracyclineAUREOMYCIN ChlortetracyclineAUREOSUP Chlortetracycline
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Proprietary Name British Approved name Proprietary Name British Approved nameAUROFAC ChlortetracyclineAUROID Tyrothricin + NitrofurazoneAUROMIX ChlortetracyclineAUROTO Thiabendazole + AmethocaineAUTAN DiethyltoluamideAUTOWORM OxfendazoleAVATEC LasalocidAVICEL RC Dispersible CelluloseAVLOCHLOR ChloroquineAVOMINE Promethazine TheoclateAVOTAN AvoparcinAXID NizatidineAZACTAM AztreonamAZAMUNE AzathioprineAZIUM DexamethasoneBACTRIM Co-trimoxazoleBACTROBAN MupirocinBAMBEC BambuterolBARATOL IndoraminBARRICADE CypermethrinBAXAN CefadroxilBAYCARON MefrusideBAYCOX ToltrazurilBAYTICOL FlumethrinBAYVAROL FlumethrinBAYVERM FebantelBC CyanocobalaminBC 500 Pantothenic AcidBDP SPACEHALER BeclomethasoneBEATITCH PermethrinBECLAZONE BeclomethasoneBECLOFORTE BeclomethasoneBECODISKS BeclomethasoneBECONASE BeclomethasoneBECOTIDE BeclomethasoneBEDRANOL PropranololBENADON PyridoxineBENDOGEN BethanidineBENEMID ProbenecidBENERVA ThiamineBENORAL BenorylateBENYLIN DiphenhydramineBENZAMYCIN ErythromycinBENZTRONE OestradiolBERENIL DiminazeneBERKACE AcepromazineBERKATENS VerapamilBERKOLOL PropranololBERKOZIDE BendrofluazideBEROFOR Interferon AlfaBEROTEC FenoterolBETA-ADALAT Atenolol + NifedipineBETA-CARDONE SotalolBETA-PROGRANE Propranolol
BETACAP BetamethasoneBETACROM SalbutamolBETADINE Povidone-IodineBETAGAN LevobunololBETALOC MetoprololBETAMOX AmoxycillinBETIM TimololBETNELAN BetamethasoneBETNESOL BetamethasoneBETNOVATE BetamethasoneBETNOVATE RECTAL LignocaineBETNOVATE-C ClioquinolBETOPTIC BetaxololBETSOLAN BetamethasoneBETSOLAN SOLUBLE BetamethasoneBETSOVET BetamethasoneBETTAMOUSSE BetamethasoneBEXTASOL BetamethasoneBEZALIP BezafibrateBIANTRAZOLE LosoxantroneBICILLIN Benzylpenicillin + Procaine
PenicillinBICNU CarmustineBILIGRAFIN IodipamideBILIGRAM Ioglycamic AcidBILIODYL PhenobutiodilBILISCOPIN Iotroxic AcidBILOPTIN Sodium IpodateBILOSIN TylosinBIMADINE SulphadimidineBIMALONG SulphamethoxypyridazineBIMATRIM-CO SulfadoxineBIMOTROM TrimethoprimBIMOXYL AmoxycillinBINOVUM NorethisteroneBIONEM LevamisoleBIOPLEX CarbenoxoloneBIORAL CarbenoxoloneBIORPHEN OrphenadrineBIOTET OxytetracyclineBIRP DimethiconeBISOLVOMYCIN BromhexineBISOLVON BromhexineBITREX Denatonium BenzoateBK ACE AcepromazineBLOAT GUARD PoloxaleneBLOCADREN TimololBONEFOS Clodronic AcidBONJELA Cetalkonium Chloride + Choline
SalicylateBORGAL Sulfadoxine + TrimethoprimBOVEX OxfendazoleBRADOSOL Benzalkonium ChlorideBRADOSOL PLUS Domiphen Bromide + Lignocaine
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Proprietary Name British Approved name Proprietary Name British Approved nameBRETYLATE Bretylium TosylateBREVIBLOC EsmololBREVINOR NorethisteroneBRICANYL TerbutalineBRIETAL MethohexitoneBRITAJECT ApomorphineBRITIAZEM DiltiazemBRITLOFLEX LofexidineBROCADOPA LevodopaBROFLEX BenzhexolBROLENE OINTMENT DibromopropamidineBROLENEEYE DROPS PropamidineBRONCHODIL ReproterolBROVON Atropine + PapaverineBRUFEN IbuprofenBUCCASTEM ProchlorperazineBUDALE ParacetamolBUDENOFALK BudesonideBURINEX BumetanideBURINEX A AmilorideBUSCOPAN HyoscineBUSCOPAN
COMPOSITUM DipyroneBUSPAR BuspironeBUTA-LEUCOTROPIN CinchophenC.A.M. ButethamateCABASER CabergolineCACIT D CholecalciferolCAELYX DoxorubicinCAFERGOT ErgotamineCALABREN GlibenclamideCALADRYL DiphenhydramineCALAZEM DiltiazemCALCEOS CholecalciferolCALCICARD DiltiazemCALCICHEW D CholecalciferolCALCIJEX CalcitriolCALCIMAX Pantothenic AcidCALCIPARINE HeparinCALCITARE CalcitoninCALCORT DeflazacortCALGEL Cetylpyridinium Chloride +
LignocaineCALPOL ParacetamolCALSYNAR SalcatoninCAM EphedrineCAMSILON Edrophonium ChlorideCANAURAL FramycetinCANDEREL AspartameCANESTEN ClotrimazoleCANISONE BetamethasoneCANOVEL PermethrinCANOVEL (COLLARS) DiazinonCANOVEL TAPEWORMER Dichlorophen
CANUSAL HeparinCAPASTAT CapreomycinCAPLENAL AllopurinolCAPOTEN CaptoprilCAPOZIDE CaptoprilCAPRIN AspirinCAPRITECT CetrimideCAPSUVAC Danthron + Docusate SodiumCARACE LisinoprilCARBICRAM NicarbazinCARBOMIX CarbomerCARBOPOL CarbomerCARDENE NicardipineCARDILATE NifedipineCARDIO-CONRAY Iothalamic AcidCARDIO-TABS DigitoxinCARDIOLITE Technetium[99mTc] SestamiCARDIOVET EnalaprilCARDURA DoxazosinCARISOMA CarisoprodolCARYLDERM CarbarylCASODEX BicalutamideCATAFLAM DiclofenacCATAPRES ClonidineCATOVEL PermethrinCATOVEL (COLLARS) DiazinonCATOVEL TAPEWORMER DichlorophenCAVERJECT AlprostadilCCNU LomustineCEANEL Phenethyl AlcoholCEDAX CeftibutenCEDOCARD Isosorbide DinitrateCEFROM CefpiromeCEFZIL CefprozilCELANCE PergolideCELBENIN MethicillinCELECTOL CeliprololCELLCEPT Mycophenolic AcidCEPOREX CephalexinCEPOXILLIN CERATE CephoxazoleCEPRAVIN CephaloniumCEPRAVIN DRY COW V CephaloniumCEREDASE AlgluceraseCERUBIDIN DaunorubicinCERUMOL ChlorbutolCESAMET NabiloneCETAVLEX CetrimideCETRIAD CetrimideCHANAVERM LevamisoleCHANAZINE XylazineCHANAZOLE MebendazoleCHEMOTRIM Co-trimoxazoleCHENDOL Chenodeoxycholic AcidCHENOFALK Chenodeoxycholic Acid
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Proprietary Name British Approved name Proprietary Name British Approved nameCHLORACTIL ChlorpromazineCHLOROMYCETIN ChloramphenicolCHLORSOL ChlortetracyclineCHOLEDYL Choline TheophyllinateCHORULON Chorionic GonadotrophinCHRONOGEST FlugestoneCI MORDANT YELLOW OlsalazineCICATRIN BacitracinCIDOMYCIN GentamicinCILEST NorgestimateCILOXAN CiprofloxacinCINOBAC CinoxacinCIPRAMIL CitalopramCIPROXIN CiprofloxacinCISTOBIL Iopanoic AcidCITANEST PrilocaineCITANEST WITH
OCTAPRESSIN FelypressinCLAFORAN CefotaximeCLAIRVAN EthamivanCLAMOXYL AmoxycillinCLARITYN LoratadineCLEXANE Enoxaparin SodiumCLIMAGEST Norethisterone + OestradiolCLIMAVAL OestradiolCLIMESSE Norethisterone + OestradiolCLINACOX DiclazurilCLINICIDE CarbarylCLINORIL SulindacCLOBURATE ClobetasoneCLOMID ClomipheneCLOPIXOL ZuclopenthixolCLOTAM Tolfenamic AcidCLOZARIL ClozapineCO-BETALOC MetoprololCOBALIN-H HydroxocobalaminCOBUTALIN SalbutamolCODAFEN IbuprofenCODALAX Danthron + PoloxamerCODIS Co-codaprinCOFORTA ButafosfanCOGENTIN BenztropineCOLAZIDE BalsalazideCOLESTID ColestipolCOLIFOAM HydrocortisoneCOLOFAC MebeverineCOLOFAC LIQUID MebeverineCOLOMYCIN ColistinCOLOMYCIN INJECTION Colistin SulphomethateCOLVSONE DexamethasoneCOMBIDOL Chenodeoxycholic Acid +
Ursodeoxycholic AcidCOMBINEX LevamisoleCOMBIVENT Ipratropium Bromide + SalbutamolCOMBIVIR Lamivudine + Zidovudine
COMOX Co-trimoxazoleCOMPANAZONE PhenylbutazoneCOMPANION Dichlorophen + PermethrinCOMPLOMENT
CONTINUS PyridoxineCOMPOSITUM CloquinateCOMPRECIN EnoxacinCOMPROPEN AmpicillinCOMTAN EntacaponeCOMTESS EntacaponeCONCAVIT Dexpanthenol + Pantothenic AcidCONCORDIN ProtriptylineCONDROTEC NaproxenCONDYLINE PodophyllotoxinCONODERM MiconazoleCONOTRANE Benzalkonium ChlorideCONRAY 280 Iothalamic AcidCONRAY 325 Iothalamic AcidCONRAY 420 Iothalamic AcidCONTAC COUGHCAPS DextromethorphanCONVULEX Valproic AcidCOOPER’S HEAD TO
TAIL BunamidineCOOPER’S MD POWDER
DIP ChlorfenvinphosCOPPERTONE SUPER-
SHADE PadimateCORACTENT NifedipineCORDARONE-X AmiodaroneCORDILOX VerapamilCORGARD NadololCORGARETIC Bendrofluazide + NadololCORIBAN DiamphenethideCORLAN HydrocortisoneCORTISYL CortisoneCORTOCAPS HydrocortisoneCORVENTAL-D TheophyllineCORWIN XamoterolCORYZIUM FurazolidoneCOSALGESTIC Co-proxamolCOSMEGEN LYOVAC Actinomycin + DactinomycinCOSOPT DorzolamideCOSURIC AllopurinolCOVERSYL PerindoprilCOVINAN ProligestoneCOXOID AmproliumCOYDEN ClopidolCOZAAR LosartanCRADOCAP CetrimideCREON PancreatinCRESTAR Norgestomet + OestradiolCROMOVET Cromoglycic AcidCROVECT CypermethrinCRYSTAPEN BenzylpenicillinCUJEC Cuproxoline
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Proprietary Name British Approved name Proprietary Name British Approved nameCUPROFEN IbuprofenCURAZOLE FenbendazoleCYCARB NicarbazinCYCLIMORPH Cyclizine + MorphineCYCLO-PROGYNOVA Levonorgestrel + Norgestrel +
OestradiolCYCLOGEST ProgesteroneCYCOSTAT RobenidineCYFAC ChlortetracyclineCYKLOKAPRON Tranexamic AcidCYMEVENE GanciclovirCYPOR CypermethrinCYPROSTAT CyproteroneCYSTRIN OxybutyninCYTACON CyanocobalaminCYTAMEN CyanocobalaminCYTOSAR CytarabineCYTOTEC MisoprostolDAKTACORT MiconazoleDAKTARIN MiconazoleDALACIN ClindamycinDALIVIT Pantothenic AcidDALMANE FlurazepamDALOPHYLLINE EtamiphyllineDANERAL SA PheniramineDANOL DanazolDANTRIUM DantroleneDAONIL GlibenclamideDARAPRIM PyrimethamineDAUNOXOME DaunorubicinDDAVP DesmopressinDEBRISAN DextranomerDECA-DURABOLIN NandroloneDECADRON DexamethasoneDECAPEPTYL TriptorelinDECAZOLE LevamisoleDECCOX DecoquinateDECLINAX DebrisoquineDECTOMAX DoramectinDEEP RELIEF IbuprofenDEFENCARE PermethrinDEFENCAT PermethrinDEFENDOG PermethrinDEFUNGIT Bensuldazic AcidDELFEN NonoxinolDELTACORTRIL PrednisoloneDELTASTAB PrednisoloneDELVOPRIM Co-trimazineDELVOSTERON ProligestoneDENTOMYCIN MinocyclineDEOSECT CypermethrinDEPAKOTE Semisodium ValproateDEPIXOL FlupenthixolDEPO-MEDRONE MethylprednisoloneDEPO-PROVERA Medroxyprogesterone
DEPOCILLIN Procaine PenicillinDEPOPEN Benzathine PenicillinDEPOSTAT GestronolDEQUACAINE Dequalinium ChlorideDEQUADIN Dequalinium ChlorideDERASECT Carbaryl + DiazinonDERBAC-C CarbarylDERBAC-M MalathionDERMALEX Allantoin + HexachlorophaneDERMOBION NitrofurazoneDERMOL Benzalkonium ChlorideDERMOL PLUS PhosmetDERMOVATE ClobetasolDESERIL MethysergideDESFERAL DesferrioxamineDESMOSPRAY DesmopressinDESMOTABS DesmopressinDESTOLIT Ursodeoxycholic AcidDETECLO Chlortetracycline +
Demeclocycline + TetracyclineDETRUNORM PropiverineDETRUSITOL TolterodineDETTOL ChloroxylenolDEVOMYCIN StreptomycinDEVOMYCIN-D Dihydrostreptomycin +
StreptomycinDEXA-RHINASPRAY Dexamethasone + TramazolineDEXACOMPLEX TripelennamineDEXADRESON DexamethasoneDEXAFORT DexamethasoneDEXAMYCIN DexamethasoneDEXAZONE DexamethasoneDEXEDRINE DexamphetamineDEXON Polyglycolic AcidDEXTRAVEN DextranDEXTROGESTIC Co-proxamolDF 118 DihydrocodeineDHC-COTINUS DihydrocodeineDIABINESE ChlorpropamideDIAGESIL DiamorphineDIAGINOL Sodium AcetrizoateDIAGNEX BLUE AzuresinDIAMICRON GliclazideDIAMOX AcetazolamideDIANETTE CyproteroneDIAREZE LoperamideDIARREST DicyclomineDIAZADIP DiazinonDIAZEMULS DiazepamDIBENYLINE PhenoxybenzamineDICLOMAX DiclofenacDICLOTARD DiclofenacDICLOVOL DiclofenacDICLOZIP DiclofenacDICLOFLEX Diclofenac
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Proprietary Name British Approved name Proprietary Name British Approved nameDICONAL Cyclizine + DipipanoneDICYNENE EthamsylateDIDRONEL Etidronic AcidDIFFERIN AdapaleneDIFFLAM BenzydamineDIFLUCAN FluconazoleDIGENAC DiclofenacDILZEM DiltiazemDIMER X Iocarmic AcidDIMETRIOSE GestrinoneDIMOTANE BrompheniramineDIMOTANE PLUS BrompheniramineDIMOTAPP P BrompheniramineDIMYRIL IsoaminileDINDEVAN PhenindioneDIOCALM ULTRA LoperamideDIOCTYL Docusate SodiumDIODERM HydrocortisoneDIONOSIL PropyliodoneDIPENTUM OlsalazineDIPIVEFRIN DipivefrineDIPRIVAN PropofolDIPROSALIC BetamethasoneDIPROSONE BetamethasoneDIRYTHMIN DisopyramideDISADINE PovidoneDISIPAL OrphenadrineDISPRIN CV AspirinDISPROL ParacetamolDISTACLOR CefaclorDISTALGESIC Co-proxamolDISTAMINE PenicillamineDISULPHINE BLUE Sulphan BlueDITHROCREAM DithranolDITHROLAN DithranolDITROPAN OxybutyninDIUMIDE-K FrusemideDIUREXAN XipamideDIURIDE FrusemideDIXARIT ClonidineDO-DO TheophyllineDOBUTREX DobutamineDOLETHAL PentobarbitoneDOLMATIL SulpirideDOLOBID DiflunisalDOLOXENE DextropropoxypheneDOMICAL AmitriptylineDOMITOR MedetomidineDOMOSEDAN DetomidineDOMPERAMOL DomperidoneDOPACARD DopexamineDOPAMET MethyldopaDOPRAM DoxapramDORALESE IndoraminDOSTINEX Cabergoline
DOUBLE-CHECK NonoxinolDOVONEX CalcipotriolDOZIC HaloperidolDRAMAMINE DimenhydrinateDRAPOLENE Benzalkonium ChlorideDROGENIL FlutamideDROLEPTAN DroperidolDRONIT PraziquantelDROPLIX DiazinonDRYPTAL FrusemideDTIC-DOME DacarbazineDUFULVIN GriseofulvinDULCOLAX BisacodylDUO-AUTOHALER PhenylephrineDUOCORT DexamethasoneDUOVENT Fenoterol + Ipratropium BromideDUPHA-DUOCORT DexamethasoneDUPHACILLIN AmpicillinDUPHACORT BetamethasoneDUPHACORT Q DexamethasoneDUPHACORT DexamethasoneDUPHACYCLINE OxytetracyclineDUPHAFROL CholecalciferolDUPHALAC LactuloseDUPHAMISOLE LevamisoleDUPHAMOX AmoxycillinDUPHAPEN Benzathine PenicillinDUPHASTON DydrogesteroneDUPHATRIM POULTRY FORMULASulfaquinoxalineDUPHATRIM SulphadiazineDUPHATRIM TrimethoprimDUPLOCILLIN Benzathine PenicillinDURAGEL NonoxinolDURATESTON TestosteroneDUROGESIC FentanylDUROMINE PhentermineDUTONIN NefazodoneDUVICULINE IsoxsuprineDY-SECT Alpha-CypermethrinDYAZIDE Co-triamterzideDYNAMIN Isosorbide MononitrateDYNESE MagaldrateDYSPAMET CimetidineDYTAC TriamtereneDYTIDE Benzthiazide + TriamtereneEASY TAPE DichlorophenEAZI-BREED ProgesteroneEBUFAC IbuprofenECONACORT EconazoleECONAPEN Procaine PenicillinECOSTATIN EconazoleECTOMORT PropetamphosEDECRIN Ethacrynic AcidEDRONAX ReboxetineEFAMAST Gamolenic Acid
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Proprietary Name British Approved name Proprietary Name British Approved nameEFCORTELAN HydrocortisoneEFCORTESOL HydrocortisoneEFEXOR VenlafaxineEFUDIX FluorouracilELANCOBAN MonensinELANTAN Isosorbide MononitrateELAVIL AmitriptylineELDEPRYL SelegilineELDISINE VindesineELLEST DUET Norethisterone + OestradiolELLEST SOLO OestradiolELOCON MometasoneELTROXIN ThyroxineELUDRIL MOUTHWASH ChlorbutolELUDRIL SPRAY AmethocaineELYZOL MetronidazoleEMBACILLIN AmpicillinEMBACLOX DC CloxacillinEMBACYCLINE OxytetracyclineEMBION TamoxifenEMCOR BisoprololEMEQUELLE MetoclopramideEMESIDE EthosuximideEMFLEX AcemetacinEMINASE AnistreplaseEMKO Benzethonium ChlorideEMLA Lignocaine + PrilocaineEMTRYL DimetridazoleEMULSIDERM Benzalkonium ChlorideENDOBIL Iodoxamic AcidENDOGRAFIN IodipamideENDOREM FerumoxidesENDOXANA CyclophosphamideENGEMYCIN OxytetracyclineENTERODOX OlaquindoxENTEROLYTE PhthalylsulphacetamideENTEROLYTE-CF FurazolidoneENTEROMIDE Sulphaloxic AcidENTOCORT BudesonideENZYPAN OxacillinEPANUTIN PhenytoinEPIFRIN AdrenalineEPILIM Valproic AcidEPIPEN AdrenalineEPIVIR LamivudineEPOGAM Gamolenic AcidEPPY AdrenalineEPREX Epoetin AlfaEQUAGESIC Aspirin + Meprobamate +
EthoheptazineEQUANIL MeprobamateEQUI-PALAZONE PhenylbutazoneEQUIDIN OxibendazoleEQUIFULVIN GriseofulvinEQUILOX Haloxon
EQUIPROXEN NaproxenEQUITAC OxibendazoleEQUITRIM Co-trimazineEQUIVITE CypermethrinEQUIVURM PLUS MebendazoleEQUIZOLE ThiabendazoleEQVALAN IvermectinERWINASE CrisantaspaseERYCEN ErythromycinERYMAX ErythromycinERYTHROCIN PREMIX ErythromycinESCALOL 507 PadimateESKAZOLE AlbendazoleESKORNADE DiphenylpyralineESMERON Rocuronium BromideESTRACOMBI Norethisterone + OestradiolESTRACYT EstramustineESTRADERM OestradiolESTRADURIN Mepivacaine + Polyestradiol
PhosphateESTRAPAK Norethisterone + OestradiolESTRING OestradiolESTRUMATE CloprostenolETHACILIN Benzathine PenicillinETHRANE EnfluraneETHYOL AmifostineEUCARDIC CarvedilolEUDEMINE DiazoxideEUGLUCON GlibenclamideEUGYNON LevonorgestrelEUMOVATE ClobetasoneEURAX CrotamitonEURAX-HYDROCORT-
ISONE HydrocortisoneEUTHANASIA PentobarbitoneEUTHATAL PentobarbitoneEUTHESATE PentobarbitoneEVISTA RaloxifeneEVOREL OestradiolEVOREL CONTI Norethisterone + OestradiolEVOREL-PAK NorethisteroneEVOXIN TABLETS DomperidoneEX-LAX PhenolphthaleinEXELDERM SulconazoleEXHELM MorantelEXIREL PirbuterolEXITAL PentobarbitoneEXOLAN Dithranol + OfloxacinEXOLAN LOTION DithranolEXOSURF Colfosceril PalmitateEXOVIR HZ Interferon AlfaEXPIRAL PentobarbitoneEXPULIN ChlorpheniramineEXSPOT PermethrinFAMVIR Famciclovir
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Proprietary Name British Approved name Proprietary Name British Approved nameFANALGIC ParacetamolFANSIDAR Pyrimethamine + SulfadoxineFARESTON ToremifeneFARLUTAL MedroxyprogesteroneFASIGYN TinidazoleFAVERIN FluvoxamineFEBRILIX ParacetamolFECTRIM Co-trimoxazoleFELDENE PiroxicamFEMAPAK Dydrogesterone + OestradiolFEMARA LetrozoleFEMIGRAINE CyclizineFEMODEN GestodeneFEMOSTON Dydrogesterone + OestradiolFEMSEVEN OestradiolFEMULEN EthynodiolFENBID IbuprofenFENDAZOLE FenbendazoleFENOPRON FenoprofenFENOX PhenylephrineFENTAMOX TamoxifenFENTAZIN PerphenazineFERROMAX CyanocobalaminFERTAGYL GonadorelinFERTIRAL GonadorelinFIBRISCINT BiciromabFILAIR BeclomethasoneFINABIOTIC Flunixin + OxytetracyclineFINADYNE FlunixinFINAJET TrenboloneFLAGYL MetronidazoleFLAGYL S Metronidazole BenzoateFLAMAZINE SulphadiazineFLAMRASE DiclofenacFLAVOMYCIN BambermycinFLAXEDIL GallamineFLEACARE CarbarylFLECTRON CypermethrinFLEMOXIN AmoxycillinFLETCHER’S
ENEMETTE Docusate SodiumFLEXADIN FenbendazoleFLEXIN IndomethacinFLIXONASE FluticasoneFLIXOTIDE FluticasoneFLOLAN Epoprostenol SodiumFLOMAX TamsulosinFLORINEF FludrocortisoneFLOXAPEN SYRUP FlucloxacillinFLUANXOL FlupenthixolFLUBENOL FlubendazoleFLUDARA Fludarabine PhosphateFLUKANIDE RafoxanideFLUKIVER ClosantelFLUOROVETS Fluorescein
FLUOSOL Perfluamine + PerflunafeneFLUOTHANE HalothaneFLUVET FlumethasoneFLY DIP ChlorfenvinphosFLY REPELLENT CrotoxyfosFLYAWAY FenvalerateFLYPOR PermethrinFLYTE PropetamphosFML FluorometholoneFML-NEO FluorometholoneFORADIL EformoterolFORANE IsofluraneFORTAGESIC PentazocineFORTEKOR BenazeprilFORTIPINE NifedipineFORTRAL PentazocineFORTUM CeftazidimeFOSAMAX Alendronic AcidFOSCAVIR Foscarnet SodiumFOSTIN Serum GonadotrophinFOSTON ToldimfosFRADOR ChlorbutolFRAGMIN Dalteparin SodiumFRAMOMYCIN FramycetinFRAMYCORT FramycetinFRAMYGEN FramycetinFRANOL EXPECT EphedrineFRANOL PLUS EphedrineFRANOL TheophyllineFRANOLYN SED DextromethorphanFRANTIN Bephenium HydroxynaphthoaFRISIUM ClobazamFROBEN FlurbiprofenFRONTLINE FipronilFROOP FrusemideFRU-CO Co-amilofruseFRUMIL Co-amilofruseFRUSEMEK Co-amilofruseFRUSENE Frusemide + TriamtereneFRUSID FrusemideFUCIBET Betamethasone + Fusidic AcidFUCIDIN Fusidic AcidFUCITHALMIC Fusidic AcidFULCIN GriseofulvinFULL MARKS PhenothrinFUMIDIL B FumagillinFUNGILIN AmphotericinFUNGIZONE AmphotericinFURADANTIN NitrofurantoinFURAMIDE DiloxanideFURASOL FuraltadoneFUREXEL IvermectinFUROXONE FurazolidoneFYBOLGEL
MEBEVERINE Mebeverine
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Proprietary Name British Approved name Proprietary Name British Approved nameGALAKE DihydrocodeineGALENAMET CimetidineGALENAMOX AmoxycillinGALPROFEN IbuprofenGALPSEUD PLUS ChlorpheniramineGAMANIL LofepramineGANDA Adrenaline + GuanethidineGAPEX NitroxynilGARAMYCIN GentamicinGASTRO-CONRAY Iothalamic AcidGASTROBID MetoclopramideGASTROCOTE Alginic AcidGASTROGRAFIN Diatrizoic AcidGASTROMAX MetoclopramideGASTROZEPIN PirenzepineGAVISCON Alginic AcidGEATRIM SulphadiazineGELTEARS CarbomerGEMZAR GemcitabineGENEBILE MenbutoneGENESA ArbutamineGENOTROPIN SomatropinGENTICIN GentamicinGENTISONE HC GentamicinGENTRAN DextranGEREF SermorelinGERMOLENE Octaphonium ChlorideGESTONE ProgesteroneGLANDOSANE CarmelloseGLAUCOL TimololGLEPTOSIL GleptoferronGLIBENESE GlipizideGLUCAGEN GlucagonGLUCOBAY AcarboseGLUCOPHAGE MetforminGLURENORM GliquidoneGLYPRESSIN TerlipressinGOLD FLEECE DiazinonGOLDEN EYE DROPS PropamidineGOLDEN EYE
OINTMENT DibromopropamidineGONADOTRAPHON LH Chorionic GonadotrophinGRANEODIN GramicidinGRANOCYTE LenograstimGREGODERM PolymyxinGRISOVIN GriseofulvinGUANOR DiphenhydramineGYNO-DAKTARIN MiconazoleGYNO-PEVARYL EconazoleGYNOL II NonoxinolHAELAN FlurandrenoloneHAEMACCEL PolygelineHALCIDERM HalcinonideHALDOL HaloperidolHALF-INDERAL Propranolol
HALFAN HalofantrineHAPADEX NetobiminHARKANKER-SOLUBLE DimetridazoleHAYMINE ChlorpheniramineHEDEX ParacetamolHEDEX IBUPROFEN IbuprofenHEMABATE CarboprostHEMINEVRIN ChlormethiazoleHEMOCANE LignocaineHEMOFIBRINE Bovine FibrinHEPSAL HeparinHERPETAD AciclovirHERPID Dimethyl Sulphoxide + IdoxuridineHESPAN HetastarchHEXABRIX Ioxaglic AcidHEXOCIL HexetidineHEXOPAL Inositol NicotinateHIPREX Hexamine HippurateHISMANAL AstemizoleHISTAFEN TerfenadineHISTALIX DiphenhydramineHISTOACRYL EnbucrilateHIVID ZalcitabineHONVAN FosfestrolHORMONIN Oestradiol + OestroneHORMONIN OestriolHORSEGUARD FenticlorHOSTACAIN ButanilicaineHUMALOG Insulin LisproHUMAN ACTRAPHANE Biphasic Isophane InsulinHUMAN ACTRAPID Human InsulinHUMAN ACTROPHANE Human InsulinHUMAN INITARD Biphasic Isophane InsulinHUMAN INITARD Human InsulinHUMAN INSULATARD Isophane InsulinHUMAN LENTE Insulin Zinc SuspensionHUMAN MIXTARD Human InsulinHUMAN MONOTARD Human InsulinHUMAN PROTAPHANE Human InsulinHUMAN ULTRATARD Insulin Zinc SuspensionHUMAN VELOSIN Human InsulinHUMAN VELOSULIN Insulin InjectionHUMANULYRATARD Human InsulinHUMATROPE SomatropinHUMEGON Chorionic GonadotrophinHUMEGON FD Human Menopausal GonadotrHUMULIN Human InsulinHUMULIN I Isophane InsulinHUMULIN S Insulin InjectionHUMULIN ZN Insulin Zinc SuspensionHUMULINS M-M Biphasic Isophane InsulinHYALASE HydralazineHYALGAN Hyaluronic AcidHYALOVET Hyaluronic AcidHYCAMTIN Topotecan
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Proprietary Name British Approved name Proprietary Name British Approved nameHYDERGINE Co-dergocrine MesylateHYDREA HydroxyureaHYDRENOX HydroflumethiazideHYDROCORTISTAB HydrocortisoneHYDROCORTISYL HydrocortisoneHYDROCORTONE HydrocortisoneHYDROLED FrusemideHYDROSALURIC HydrochlorothiazideHYGROTON ChlorthalidoneHYLARTIL Hyaluronic AcidHYPAQUE Diatrizoic AcidHYPERTANE AmilorideHYPNODIL MetomidateHYPNOMIDATE EtomidateHYPNORM Fentanyl + FluanisoneHYPNOVEL MidazolamHYPOVASE PrazosinHYPURIN ISOPHANE Isophane InsulinHYPURIN LENTE Insulin Zinc SuspensionHYPURIN NEUTRAL Insulin InjectionHYPURIN NEUTRAL Neutral Insulin InjectionHYTRAST Iopydol + IopydoneHYTRIN TerazosinIBUFAC IbuprofenIBULEVE IbuprofenIBUSPRAY IbuprofenICHTHOPASTE IchthammolICODIAL IcodextrinICTHABAND IchthammolIDURIDIN Dimethyl Sulphoxide + IdoxuridineIKOREL NicorandilILOSONE Erythromycin EstolateILUBE Acetylcysteine + HypromelloseIMAVEROL EnilconazoleIMBRILON IndomethacinIMDUR Isosorbide MononitrateIMIGRAN SumatriptanIMIZOL ImidocarbIMMOBILON Acepromazine + Etorphine +
MethotrimeprazineIMODIUM LoperamideIMPLIXA OestradiolIMPROVERA MedroxyprogesteroneIMTACK Isosorbide DinitrateIMUNOVIR Inosine PranobexIMURAN AzathioprineINDERAL PropranololINDERETIC Bendrofluazide + PropranololINDEREX Bendrofluazide + PropranololINDOCID IndomethacinINDOLAR IndomethacinINDOMAX IndomethacinINDOMOD IndomethacinINFADROPS ParacetamolINFLAM Ibuprofen
INNOHEP Tinzaparin SodiumINNOVACE EnalaprilINNOZIDE EnalaprilINOVEN IbuprofenINSTILLAGEL LignocaineINSUVET Insulin InjectionINTAL Cromoglycic AcidINTAL COMPOUND IsoprenalineINTAL COMPOUND Cromoglycic AcidINTEGRIN OxypertineINTRA-EPICAINE MepivacaineINTRACYCLINE OxytetracyclineINTRADINE SulphadimidineINTRALGIN SalicylamideINTRAMYCETIN ChloramphenicolINTRAVAL ThiopentoneINTRAVIT CyanocobalaminINTRONA Interferon AlfaINVICORP AviptadilINVIRASE SaquinavirIODOSORB Cadexomer-IodineIONAMIN PhentermineIONAX SCRUB Benzalkonium ChlorideIONIL T Benzalkonium ChlorideIOPIDINE ApraclonidineIPRAL TrimethoprimISAVERIN Dipyrone + MethindizateISCLOFEN DiclofenacISIB Isosorbide MononitrateISISFEN IbuprofenISMELIN GuanethidineISMO Isosorbide MononitrateISOKET Isosorbide DinitrateISOPTO ATROPINE AtropineISOPTO CARBACHOL CarbacholISOPTO CARPINE PilocarpineISOPTO EPINAL AdrenalineISOPTO HypromelloseISORDIL Isosorbide DinitrateISOTRATE Isosorbide MononitrateISOTREX IsotretinoinISOTREXIN Erythromycin + IsotretinoinISOVORIN Calcium LevofolinateISTIN AmlodipineIVOMEC IvermectinIVOMEC-F ClorsulonJERIDIN Isosorbide DinitrateJUNIFEN IbuprofenKABIKINASE StreptokinaseKALSPARE Chlorthalidone + TriamtereneKALTEN Amiloride + AtenololKANNASYN KanamycinKEFADIM CeftazidimeKEFADOL Cephamandole NafateKEFLEX Cephalexin
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Proprietary Name British Approved name Proprietary Name British Approved nameKEFTID CefaclorKEFZOL CephazolinKELFIZINE W SulfametopyrazineKEMADRIN ProcyclidineKEMICETINE ChloramphenicolKENALOG TriamcinoloneKERLONE BetaxololKEST PhenolphthaleinKETALAR KetamineKETASET KetamineKETOCID KetoprofenKETOFEN KetoprofenKETOVITE LIQUID CyanocobalaminKETOVITE Acetomenaphthone + Pantothenic
AcidKETOZIP KetoprofenKILTRIX FlumethrinKINIDIN DURULES QuinidineKLARICID ClarithromycinKLIOFEM Norethisterone + OestradiolKLIOVANCE OestradiolKLOXERATE CloxacillinKOKCISAN SalinomycinKOLANTICON DicyclomineKONAKION PhytomenadioneKYTRIL GranisetronLABOSEPT Dequalinium ChlorideLACTACLOX Ampicillin + CloxacillinLACTUGAL LactuloseLAMICTAL LamotrigineLAMISIL TerbinafineLAMPRENE ClofazimineLANOXIN DigoxinLANVIS ThioguanineLARAFLEX NaproxenLARATRIM Co-trimoxazoleLARGACTIL ChlorpromazineLARIAM MefloquineLASIKAL FrusemideLASILACTONE Frusemide + SpironolactoneLASIX FrusemideLASMA TheophyllineLASONIL HydralazineLASORIDE Co-amilofruseLATACILLIN AmpicillinLAURABOLIN NandroloneLAXOBERAL Sodium PicosulphateLEDCLAIR Sodium CalciumedetateLEDERCORT TriamcinoloneLEDERFEN FenbufenLEDERFOLIN Calcium FolinateLEDERMYCIN DemeclocyclineLEDERPAM OxazepamLEDERPUR AllopurinolLEDERSPAN Triamcinolone Hexacetonid
LEMSIP IbuprofenLENTARD MC Insulin Zinc SuspensionLENTARON FormestaneLENTICILLIN Procaine PenicillinLENTIZOL AmitriptylineLENTRAX Benzathine Penicillin + Procaine
PenicillinLEO RED DC Framycetin + Penethamate
HydriodideLEO YELLOW MC Framycetin + Penethamate
HydriodideLEOCILLIN Penethamate HydriodideLEOTROX Trimethoprim + SulfatroxazoleLERBEK Methyl BenzoquateLETHOBARB PentobarbitoneLEUCOMAX MolgramostimLEUCOTROPIN Cinchophen + QuinineLEUKERAN ChlorambucilLEUSTAT CladribineLEVACIDE LevamisoleLEVACURE LevamisoleLEVADIN LevamisoleLEVAM WORMAWAY LevamisoleLEVAPAS LevamisoleLEVASOL LevamisoleLEVIPOR LevamisoleLEVIPOR LevamisoleLEVOPHED NoradrenalineLEXOTAN BromazepamLEXPEC Folic AcidLIBRIUM ChlordiazepoxideLIBROFEM IbuprofenLIDIFEN IbuprofenLIFEN IbuprofenLIGNAVET LignocaineLIGNODREN LignocaineLIGNOL LignocaineLIGNOSTAB LignocaineLINCO-SPECTIN SpectinomycinLINCO-SPECTIN LincomycinLINCOCIN LincomycinLINCOLN Oxibendazole + PermethrinLINCOMIX LincomycinLINGRAINE ErgotamineLIORESAL BaclofenLIPANTIL FenofibrateLIPFLAVONOID HydroxocobalaminLIPOSTAT PravastatinLIPOTRIAD HydroxocobalaminLITHOFALK Chenodeoxycholic Acid +
Ursodeoxycholic AcidLIVIAL TiboloneLIVOSTIN LevocabastineLOCABIOTAL FusafungineLOCAIN Lignocaine
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Proprietary Name British Approved name Proprietary Name British Approved nameLOCERYL AmorolfineLOCOID HydrocortisoneLOCOID C Chlorquinaldol + HydrocortisoneLOCOID CRELO HydrocortisoneLOCORTEN-VIOFORM ClioquinolLOCORTEN-VIOFORM FlumethasoneLOCOVETIC Adrenaline + LignocaineLODINE EtodolacLODITAC OxibendazoleLOESTRIN 20 NorethisteroneLOFENSAID DiclofenacLOGYNON LevonorgestrelLOMEXIN FenticonazoleLOMODEX DextranLOMOTIL Co-phenotropeLOMUSOL Cromoglycic AcidLONITEN MinoxidilLOPATOL NitroscanateLOPERAGEN LoperamideLOPID GemfibrozilLOPRANOL PropranololLOPRESOR MetoprololLOSEC OmeprazoleLOTRIDERM Betamethasone + ClotrimazoleLOXAPAC LoxapineLUBORANT CarmelloseLUDIOMIL MaprotilineLUMIREM FerumoxsilLUSTRAL SertralineLUTALYSE DinoprostLYCLEAR PermethrinMABTHERA RituximabMACROBID NitrofurantoinMACRODANTIN NitrofurantoinMACRODEX DextranMADOPAR Co-beneldopaMAGNAPEN AmpicillinMAGNEVIST Gadopentetic AcidMALARONE Atovaquone + ProguanilMALOPRIM Dapsone + PyrimethamineMANDANOL ParacetamolMANERIX MoclobemideMANUSEPT TriclosanMANY PseudoephedrineMARBOCYL MarbofloxacinMARCAIN BupivacaineMARCAINE WITH
ADRENALINE AdrenalineMAREVAN WarfarinMARINOL Benzalkonium ChlorideMARPLAN IsocarboxazidMARVELON DesogestrelMASNODERM ClotrimazoleMASSE Sorbitan MonostearateMAXALT Rizatriptan
MAXEPA Omega-3 Marine TriglyceridesMAXIDREX Dexamethasone + HypromelloseMAXIMET IndomethacinMAXITROL Dexamethasone + HypromelloseMAXIVENT SalbutamolMAXOLON MetoclopramideMAXTREX MethotrexateMAXUS AvilamycinMC Neutral Insulin InjectionMCR Isosorbide MononitrateMEDIHALER EPI AdrenalineMEDIHALER-ERGOT-
AMINE ErgotamineMEDIHALER-ISO IsoprenalineMEDIMOL ParacetamolMEDINEX DiphenhydramineMEDISED PromethazineMEDOMET MethyldopaMEDRONE MethylprednisoloneMEFLAM Mefenamic AcidMEFOXIN CefoxitinMEGACE MegestrolMELLERIL ThioridazineMENOGON MenotrophinMENOPHASE Mestranol + NorethisteroneMENOREST OestradiolMENZOL NorethisteroneMEPRATE MeprobamateMEPTID MeptazinolMERBENTYL DicyclomineMERCILON DesogestrelMEROCAINE Bendrofluazide + Cetylpyridinium
ChlorideMEROCET Cetylpyridinium ChlorideMERONEM MeropenemMEROTHOL Cetylpyridinium ChlorideMESALIN OestradiolMESTINON Pyridostigmine BromideMETENIX MetolazoneMETOFANE MethoxyfluraneMETOPIRONE MetyraponeMETOSYN FluocinonideMETRIJET FurazolidoneMETRODIN UrofollitrophinMETROGEL MetronidazoleMETRONEX MetronidazoleMETROTOP MetronidazoleMEXITIL MexiletineMIACALSIC SalcatoninMICANOL DithranolMICETAL FlutrimazoleMICOTIL TilmicosinMICROFAC Chlortetracycline + Procaine
PenicillinMICROGYNON Levonorgestrel
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Proprietary Name British Approved name Proprietary Name British Approved nameMICROMOX AmoxycillinMICRONOR NorethisteroneMICROVAL LevonorgestrelMICTRAL Nalidixic AcidMIDAMOR AmilorideMIDICEL SulphamethoxypyridazineMIDRID IsomethepteneMIFEGYNE MifepristoneMIGRAFEN IbuprofenMIGRALEVE Buclizine + Docusate SodiumMIGRANAL DihydroergotamineMIGRAVESS Aspirin + MetoclopramideMIGRIL Cyclizine + ErgotamineMILDISON HydrocortisoneMILLOPHYLLINE-V EtamiphyllineMINILYN LynoestrenolMINIMS AMETHOCAINE AmethocaineMINOCIN MinocyclineMINODIAB GlipizideMINTEZOL ThiabendazoleMINULET GestodeneMIOCHOL Acetylcholine ChlorideMIRADOL ParacetamolMIRENA LevonorgestrelMITOMYCIN C KYOWA MitomycinMITOXANA IfosfamideMIVACRON Mivacurium ChlorideMIXTARD Biphasic Isophane InsulinMIZOLLEN MizolastineMOBIFLEX TenoxicamMODALIM CiprofibrateMODECATE FluphenazineMODISAL Isosorbide MononitrateMODITEN FluphenazineMODRASONE AlclometasoneMODRENAL TrilostaneMODUCREN Amiloride + TimololMODURET AmilorideMODURETIC AmilorideMOGADON NitrazepamMOLCER Docusate SodiumMOLIPAXIN TrazodoneMONIT Isosorbide MononitrateMONO-CEDOCARD Isosorbide MononitrateMONOCLATE-P Factor VIII FractionMONOCOR BisoprololMONODUR Isosorbide MononitrateMONOMAX Isosorbide MononitrateMONONINE Factor IX FractionMONOPARIN HeparinMONOTRIM TrimethoprimMONOVENT TerbutalineMONOZIDE BisoprololMONPHYTOL ChlorbutolMONTEBAN Narasin
MONURIL FosfomycinMONZALDON VetrabutineMORCAP MorphineMORHULIN, Cod-liver OilMOTENS LacidipineMOTIFENE DiclofenacMOTILIUM DomperidoneMOTIPRESS Fluphenazine + NortriptylineMOTIVAL Fluphenazine + NortriptylineMOTRIN IbuprofenMST CONTINUS MorphineMUCAINE OxethazaineMUCODYNE CarbocisteineMULTIBIONTA PanthenolMULTIJECT PrednisoloneMULTIPARIN HeparinMULTIVET B CyanocobalaminMUSE AlprostadilMYAMBUTOL EthambutolMYCARDOL Pentaerythritol TetranitrMYCEN OxytetracyclineMYCIL TolnaftateMYCOBUTIN RifabutinMYCOPHYT NatamycinMYCOSAN-T ErythromycinMYDRIACYL TropicamideMYDRILATE: CyclopentolateMYELOBROMOL MitobronitolMYLERAN BusulphanMYLIPEN Procaine PenicillinMYODIL IophendylateMYOSCINT Imciromab PentetateMYOTONINE Bethanechol ChlorideMYRJ 45 Polyoxyl 8 StearateMYRJ 52 Polyoxyl 40 StearateMYRJ 52S Polyoxyl 40 StearateMYSOLINE PrimidoneMYSPAMOL ProquamezineNACTON Poldine MethylsulphateNAFPENZAL NafcillinNALCROM Cromoglycic AcidNALOREX NaltrexoneNANDORAL EthyloestrenolNANDROLIN NandroloneNAPRATEC MisoprostolNAPROSYN NaproxenNAPROTEC NaproxenNARAMIG NaratriptanNARCAN NaloxoneNARDIL PhenelzineNARPHEN PhenazocineNASOBEC BeclomethasoneNATRILIX IndapamideNAVIDREX CyclopenthiazideNAVISPARE Amiloride + Cyclopenthiazide
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Proprietary Name British Approved name Proprietary Name British Approved nameNEBCIN TobramycinNEFTIN FurazolidoneNEGASUNT CoumaphosNEGRAM Nalidixic AcidNEMAFAX ThiophanateNEMICIDE LevamisoleNEO-CYTAMEN HydroxocobalaminNEO-MERCAZOLE CarbimazoleNEO-NACLEX BendrofluazideNEO-SULPHENTRIN PhthalylsulphathiazoleNEOAMFO AmphotericinNEOBIOTIC NeomycinNEOBIOTIC DRY COW HydrocortisoneNEOCIDOL DiazinonNEODIAR FurazolidoneNEOGEST NorgestrelNEOMIN NeomycinNEORAL CyclosporinNEOSPORIN Gramicidin + PolymyxinNEOTIGASON AcitretinNEPHRIL PolythiazideNERISONE DiflucortoloneNETILLIN NetilmicinNETROSYLLA EtisazoleNEULACTIL PericyazineNEUPOGEN FilgrastimNEUTREXIN TrimetrexateNICRAZIN NicarbazinNIFENSAR NifedipineNIFULIDONE FurazolidoneNILVAX LevamisoleNILVERM LevamisoleNILVERM PIG WORMER TetramisoleNILZAN OxyclozanideNILZAN LevamisoleNIMBEX Cisatracurium BesylateNIMOTOP NimodipineNIOPAM IopamidolNIPENT PentostatinNISOLONE PrednisoloneNITROCETIN-A NitrofurazoneNIVAQUINE ChloroquineNIVEMYCIN NeomycinNIZORAL KetoconazoleNOCTAMID LormetazepamNOCTEC Chloral HydrateNOLUDAR MethypryloneNOLVASAN ChlorhexidineNOOTROPIL PiracetamNOPAINE LignocaineNORADRAN DiphenhydramineNORATEX Cod-liver OilNORBET BetamethasoneNORCURON Vecuronium BromideNORDERM Sorbitan Mono-oleate
NORDITROPIN SomatropinNORFLEX OrphenadrineNORGALAX Docusate SodiumNORGESTON LevonorgestrelNORIDAY NorethisteroneNORIMIN NorethisteroneNORIMODE LoperamideNORINYL MestranolNORINYL-1 NorethisteroneNORISTERAT NorethisteroneNORITATE MetronidazoleNORLESTRIN NorethisteroneNORMAX Co-danthrusateNORMEGON Human Menopausal
GonadotrophinNORMISON TemazepamNOROBRITTIN AmpicillinNOROCILLIN Procaine PenicillinNOROCLOX CloxacillinNORODINE Co-trimazineNOROFULVIN GriseofulvinNORPLANT LevonorgestrelNORPROLAC QuinagolideNORVIR RitonavirNOVALDEX TamoxifenNOVANTRONE MitozantroneNOVOCILLIN Benzathine PenicillinNOVOMAST NovobiocinNOVONORM RepaglinideNOVOSEVEN Eptacog Alfa (Activated)NOXYFLEX NoxythiolinNOXYFLEX S AmethocaineNOZINAN MethotrimeprazineNU-SEALS ASPIRIN AspirinNUBAIN NalbuphineNUELIN TheophyllineNUFLOR FlorfenicolNUPERCAINAL CinchocaineNUPOR PhosmetNUROFEN IbuprofenNUTRIZYM GR PancreatinNUVAN STAYKIL Dichlorvos + IodofenphosNUVAN TOP Dichlorvos + FenitrothionNUVELLE Levonorgestrel + OestradiolNYCOPREN NaproxenNYMFALON Chorionic Gonadotrophin +
ProgesteroneNYSTADERMAL TriamcinoloneNYSTAMONT NystatinNYSTAN NystatinNYTOL DiphenhydramineOCCRYCETIN OxytetracyclineOCTOVIT CyanocobalaminOCTREOSCAN PentetreotideOCUCOAT Hypromellose
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Proprietary Name British Approved name Proprietary Name British Approved nameOCUSERT PILO PilocarpineOESTRIFEN TamoxifenOESTROGEL OestradiolOILATUM PLUS Benzalkonium Chloride + TriclosanOLBETAM AcipimoxOMNISOL ChlortetracyclineONAMER M Polidronium ChlorideONCOSCINT SatumomabONCOVIN VincristineONE-ALPHA AlfacalcidolOPERIDINE PhenoperidineOPHTHAINE ProxymetacaineOPILON ThymoxamineOPOBYL BioallethrinOPTHAIN Benzalkonium ChlorideOPTHAURAL ChloramphenicolOPTICLOX CloxacillinOPTICORTEN DexamethasoneOPTICORTENOL PrednisoloneOPTICORTENOL-S DexamethasoneOPTICROM Cromoglycic AcidOPTILAST AzelastineOPTIMINE AzatadineOPTIMMUNE CyclosporinORABASE CarmelloseORABET MetforminORADEXON DexamethasoneORAHESIVE CarmelloseORALDENE HexetidineORALJECT CIRCULON IsoxsuprineORALJECT MUCOLYSE BromhexineORALJECT SEDAZINE AcepromazineORAMEC IvermectinORAMORPH MorphineORANDRONE MethyltestosteroneORAP PimozideORBENIN CloxacillinORBISECT PhosmetORELOX CefpodoximeORGAFOL UrofollitrophinORIMETEN AminoglutethimideORNICURE DoxycyclineORNIMED OxytetracyclineOROJET-N NeomycinORTHO-CREME NonoxinolORTHO-FORM NonoxinolORTHO-GYNEST OestriolORTHO-NOVIN Mestranol + NorethisteroneORUDIS KetoprofenORUVAIL KetoprofenOSBIL Iobenzamic AcidOTERNA Monosulfiram + BetamethasoneOTOMIZE DexamethasoneOTORYL DibromopropamidineOTOSPORIN Polymyxin
OTRIVINE XylometazolineOTRIVINE-ANTISTIN Antazoline + XylometazolineOVALYSE FertirelinOVARID MegestrolOVESTIN OestriolOVEX MebendazoleOVITELMIN MebendazoleOVRAN LevonorgestrelOVRANETTE LevonorgestrelOVYSMEN NorethisteroneOXANID OxazepamOXFENIL OxfendazoleOXIS EformoterolOXIVENT Oxitropium BromideOXYCARE OxytetracyclineOXYCOMPLEX Flunixin + OxytetracyclineOXYDON OxytetracyclineOXYDON OxytetracyclineOXYMAST OxytetracyclineOXYMYCIN OxytetracyclineOXYSENTIN OxytetracyclineOXYTETRIN OxytetracyclineP.E.P. ChlortetracyclineP.G. Serum Gonadotrophin + Chorionic
GonadotrophinPACIFENE IbuprofenPALAPRIN AloxiprinPALDESIC ParacetamolPALFIUM DextromoramidePALLADONE HydromorphonePALOSEIN OrgoteinPALUDRINE ProguanilPAMERGAN Pethidine + PromethazinePANACUR FenbendazolePANADOL ParacetamolPANALEVE ParacetamolPANALOG TriamcinolonePANCREALAURYL TEST FluoresceinPANCREASE PancreatinPANCREX PancreatinPANGRAM GentamicinPANOMEC IvermectinPARACETS ParacetamolPARACIDE PLUS DiazinonPARAFEND OxfendazolePARAMAX MetoclopramidePARAMIN ParacetamolPARAMOL DihydrocodeinePARAPLATIN CarboplatinPARASITIC LindanePARASOL CypermethrinPARATECT MorantelPARIET RabeprazolePARLODEL BromocriptinePARNATE Tranylcypromine
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Proprietary Name British Approved name Proprietary Name British Approved namePAROVEN OxerutinsPARSTELIN Tranylcypromine + TrifluoperazinePARVOLEX AcetylcysteinePATHOCEF CefoperazonePAVACOL-D PholcodinePAVULON Pancuronium BromidePAXALGESIC Co-proxamolPAYZONE NitrovinPECRAM AminophyllinePEN—3-MAST Procaine PenicillinPENBRITIN (INJECTION) AmpicillinPENBRITIN (ORAL) AmpicillinPENDRAMINE PenicillaminePENILLIN Benzathine PenicillinPENMIX Biphasic Isophane InsulinPENTACARINATE PentamidinePENTASA MesalazinePENTASPAN PentastarchPENTAZONE NitrovinPENTOJECT PentobarbitonePENTOSTAM Sodium StibogluconatePEPCID FamotidinePEPTIMAX CimetidinePERDIX MoexiprilPERFAN EnoximonePERGOGREEN Human Menopausal
Gonadotrophin + UrofollitrophinPERGONAL MenotrophinPERIACTIN CyproheptadinePERIZIN CoumaphosPERLUTEX MedroxyprogesteronePERSANTIN DipyridamolePERTOFRAN DesipraminePEVARYL EconazolePEVARYL TC Econazole + TriamcinolonePEVIDINE Povidone-IodinePHARMATON RutosidePHARMORUBICIN EpirubicinPHENERGAN PromethazinePHENOBARBITONE
SPANSULE PhenobarbitonePHENOGEL PhenylbutazonePHENYZENE PhenylbutazonePHOR PAIN IbuprofenPHOSPHOLINE IODIDE Ecothiopate IodidePHYLLOCONTIN
CONTINUS AminophyllinePHYSEPTONE MethadonePHYSIOTENS MoxonidinePICOLAX Sodium PicosulphatePILOGEL PilocarpinePIMAVECORT NatamycinPIPORTIL PipothiazinePIPRIL PiperacillinPIRITON Chlorpheniramine
PITRESSIN ArgipressinPLACIDEX ParacetamolPLANATE CloprostenolPLANIPART ClenbuterolPLAQUENIL HydroxychloroquinePLATET AspirinPLAVIX ClopidogrelPLENDIL FelodipinePLUS PanthenolPNP EAR DROPS PolymyxinPOLYBACTRIN BacitracinPOLYFAX Bacitracin + PolymyxinPOLYQUAT Polidronium ChloridePOLYTRIM Polymyxin + TrimethoprimPONDERAX FenfluraminePONDOCILLIN Pivampicillin + PivmecillinamPONSTAN Mefenamic AcidPORECT PhosmetPORK INSULATARD Isophane InsulinPORK MIXTARD Biphasic Isophane InsulinPORK VELOSULIN Insulin InjectionPORON PhosmetPORSYN Co-trimazinePOSICOR MibefradilPOSIJECT DobutaminePOTENCIL PhenoxymethylpenicillinPOWERGEL KetoprofenPOWERPACK ChlorfenvinphosPRAGMATER Povidone-IodinePRAXILENE NaftidrofurylPRECORTISYL PrednisolonePRED FORTE PrednisolonePREDEF 2X IsoflupredonePREDENEMA PrednisolonePREDFOAM PrednisolonePREDNESOL PrednisolonePREDNO-LEUCOTROPIN CinchophenPREDSOL PrednisolonePREFERID BudesonidePREFOAM PrednisolonePREMIQUE CYCLE MedroxyprogesteronePREMPAK NorgestrelPREPIDIL DinoprostonePREPULSID CisapridePRESCAL IsradipinePRESERVEX AceclofenacPRESTIM Bendrofluazide + TimololPREVENDER DiazinonPREVENTEF DiazinonPRID Oestradiol + ProgesteronePRIMACOR MilrinonePRIMALAN MequitazinePRIMAXIN Cilastatin + ImipenemPRIMOLUT N NorethisteronePRIMOTESTON Testosterone
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Proprietary Name British Approved name Proprietary Name British Approved namePRIMPERAN MetoclopramidePRIODERM MalathionPRO-BANTHINE Propantheline BromidePRO-DYNAM PhenylbutazonePRO-VIRON MesterolonePROCTOFOAM HC PramoxinePROCTOSEDYL Cinchocaine + FramycetinPROFASI Chorionic GonadotrophinPROFLEX IbuprofenPROFTRIL AlbendazolePROGESIC FenoprofenPROGRAF TacrolimusPROGRAM LufenuronPROGYNOVA OestradiolPROHANCE GadoteridolPROHANCE Calteridol CalciumPROLEUKIN AldesleukinPROLUTON DEPOT HydroxyprogesteronePROMINAL MethylphenobarbitonePROMONE-E MedroxyprogesteronePRONDOL IprindolePRONESTYL ProcainamidePROPADERM BeclomethasonePROPAIN DiphenhydraminePROPALIN PhenylpropanolaminePROPANIX PropranololPROPEN Benethamine Penicillin +Benzathine Penicillin + Procaine PenicillinPROPESS DinoprostonePROPINE DipivefrinePROSCAR FinasteridePROSOLVIN LuprostiolPROSTAP LeuprorelinPROSTIN E DinoprostonePROSTIN F2 DinoprostPROSTIN VR AlprostadilPROSULF Protamine SulphatePROTHIADEN DothiepinPROTIUM PantoprazolePROVERA MedroxyprogesteronePROZAC FluoxetinePSORADATE DithranolPSORIN DithranolPULMADIL RimiterolPULMICORT BudesonidePUR-IN MIX Biphasic Isophane InsulinPUR-IN NEUTRAL Insulin InjectionPURI-NETHOL MercaptopurinePYLORID Ranitidine Bismuth CitratPYROGASTRONE Alginic Acid + CarbenoxoloneQUADRAMAX MenbutoneQUALAMOX AmoxycillinQUELLADA LindaneQUESTRAN CholestyramineQUILIZINE Baquiloprim + Sulphadimethoxine
QUINABAND ClioquinolRADIAN B AspirinRANIZOLE Rafoxanide + ThiabendazoleRAPIFEN AlfentanilRAPIJECT MorphineRAPILYSIN ReteplaseRAPINOVET PropofolRAPITARD MC Biphasic Insulin InjectioRAPITIL NedocromilRASTINON TolbutamideRAXAR GrepafloxacinRBC AntazolineRECEPTAL BuserelinRECORMON Epoetin BetaREFLUDAN LepirudinREFOLINON Calcium FolinateREGAINE MinoxidilRELCOFEN IbuprofenRELEFACT LH-RH/TRH Gonadorelin + ProtirelinRELIFEX NabumetoneREMEDEINE DihydrocodeineREMNOS NitrazepamREMOBILASE Hyaluronic AcidRENACHEK HyoscineRENEGADE Alpha-CypermethrinREOCETIN ChloramphenicolREPLENINE Factor IX FractionREQUIP RopiniroleRESPACAL TulobuterolRESPIROT Cropropamide + CrotethamideRESTANDOL TestosteroneRETCIN ErythromycinRETIN-A TretinoinRETINOVA TretinoinRETRO CONRAY Iothalamic AcidRETROVIR ZidovudineREVANIL LysurideREVASC DesirudinREVIVON DiprenorphineRHEOMACRODEX DextranRHEUMACIN IndomethacinRHEUMATINE AspirinRHEUMOX AzapropazoneRHINOCORT BudesonideRHINOLAST AzelastineRHUMALGAN DiclofenacRIDAURA AuranofinRIDAVERM LevamisoleRIDECT PermethrinRIFADIN RifampicinRIFATER Isoniazid + Pyrazinamide +
RifampicinRIFINAH Isoniazid + RifampicinRIKOSPRAY Cetylpyridinium ChlorideRILUTEK Riluzole
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Proprietary Name British Approved name Proprietary Name British Approved nameRIMACTANE RifampicinRIMACTAZID Isoniazid + RifampicinRIMIFON IsoniazidRIMSO-50 Dimethyl SulphoxideRINATEC Ipratropium BromideRINSTEAD Cetylpyridinium Chloride +
ChloroxylenolRIPERCOL LevamisoleRISPERIDAL RisperidoneRITALIN MethylphenidateRIVOTRIL ClonazepamRO-A-VIT RetinolROACCUTANE IsotretinoinROBAXIN MethocarbamolROBAXISAL FORTE MethocarbamolROBAXISAL AspirinROBINUL Glycopyrronium BromideROBINUL NEOSTIGMINE NeostigmineROBUST CypermethrinROCALTROL CalcitriolROCEPHIN CeftriaxoneROFERON Interferon AlfaROGITINE PhentolamineROHYPNOL FlunitrazepamROMENSIN MonensinROMOZIN TroglitazoneROMPUN XylazineRONAXAN DoxycyclineRONDOMYCIN MethacyclineRONICOL Nicotinyl AlcoholROZEX MetronidazoleRUBY Dichlorophen + PermethrinRUMAFEN DiclofenacRYCOVET DUOSPEC OxyclozanideRYCOVET ROXENTOL ChloroxylenolRYCOVET RYPOSECT PermethrinRYNACROM Cromoglycic AcidRYNACROM CO Xylometazoline + Cromoglycic
AcidRYTHMODAN DisopyramideSABRIL VigabatrinSACOX SalinomycinSAFFAN AlphaxaloneSAGATAL PentobarbitoneSAIZEN SomatropinSALAGEN PilocarpineSALAMOL SalbutamolSALAZOPYRIN SulphasalazineSALBULIN SalbutamolSALCOSTAT DinitolmideSALFURIDE NifursolSALGAIN SalinomycinSALIVA ORTHANA Gastric MucinSALOFALK MesalazineSALURIC Chlorothiazide
SALZONE ParacetamolSANDIMMUN CyclosporinSANDOSTATIN OctreotideSANOMIGRAN PizotifenSAPPHIRE PolyhexanideSAQUADIL DiaveridineSAVENTRINE IsoprenalineSAVLON ChlorhexidineSCHERING PC NorgestrelSCHERIPROCT CinchocaineSCHERIPROCT PrednisoloneSCOLINE Suxamethonium ChlorideSCOPODERM HyoscineSCOPODEX HyoscineSCORPIN Co-trimazineSEALEGS MeclozineSECADREX AcebutololSECONAL SODIUM Quinalbarbitone SodiumSECTINE Fenvalerate + PermethrinSECTRAL AcebutololSECURON VerapamilSECUROPEN AzlocillinSEDIVET RomifidineSEHCAT Tauroselcholic AcidSELDANE TerfenadineSELEXID PivemecillinamSEMIDAONIL GlibenclamideSEMITARD MC Insulin Zinc SuspensionSEMPREX AcrivastineSEOMINAL Phenobarbitone + TheodrenalineSEPTREX SulphathiazoleSEPTRIN Co-trimoxazoleSERC BetahistineSERDOLECT SertindoleSERENACE HaloperidolSERETIDE Fluticasone + SalmeterolSEROPHENE ClomipheneSEROQUEL QuetiapineSEROXAT ParoxetineSESORAL MethyltestosteroneSEVREDOL MorphineSIMPLENE AdrenalineSINEMET Co-careldopaSINEQUAN DoxepinSINGULAIR MontelukastSINTHROME NicoumaloneSKELED Tiludronic AcidSLIPJEL Benzalkonium ChlorideSLO-PHYLLIN TheophyllineSLOFENAC DiclofenacSLOW-PREN OxprenololSLOW-TRASICOR OxprenololSLOZEM DiltiazemSNO PHENICOL ChloramphenicolSNO PILO Pilocarpine
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Proprietary Name British Approved name Proprietary Name British Approved nameSODIUM AMYTAL AmylobarbitoneSOFRA-TULLE FramycetinSOFRADEX Dexamethasone + Framycetin +
GramicidinSOFRAMYCIN Framycetin + GramicidinSOLCO HIDA EtifeninSOLCOSCINT
HEPATOBIDA EtifeninSOLIAN AmisulprideSOLIVITO N CyanocobalaminSOLPAFLEX IbuprofenSOLPRIN AspirinSOLU-CORTEF HydrocortisoneSOLU-MEDRONE MethylprednisoloneSOLVITO Pantothenic AcidSOMATONORM SomatremSOMILAN Chloral BetaineSOMINEX PromethazineSOMNITE NitrazepamSONERYL ButobarbitoneSONI-SLO Isosorbide DinitrateSORBESTER P 12 Sorbitan MonolaurateSORBESTER P 16 Sorbitan MonopalmitateSORBESTER P 18 Sorbitan MonostearateSORBESTER P 37 Sorbitan TrioleateSORBESTER P 38 Sorbitan TristearateSORBESTER Q PolysorbateSORBICHEW Isosorbide DinitrateSORBID Isosorbide DinitrateSORBITRATE Isosorbide DinitrateSOTACOR SotalolSPAN 20 Sorbitan MonolaurateSPAN 40 Sorbitan MonopalmitateSPAN 60 Sorbitan MonostearateSPAN 65 Sorbitan TristearateSPAN 80 Sorbitan Mono-oleateSPAN 85 Sorbitan TrioleateSPARINE PromazineSPARTAKON LevamisoleSPARTRIX CarnidazoleSPASMONAL AlverineSPECTAM SpectinomycinSPECTRABAN PadimateSPECTRAZOL CefuroximeSPIRA SpiramycinSPIRETIC SpironolactoneSPIRO-CO Hydroflumethiazide +
SpironolactoneSPIROCTAN SpironolactoneSPIROCTAN-M Canrenoic AcidSPIROLONE SpironolactoneSPIROSPARE SpironolactoneSPORANOX ItraconazoleSPRAY OxymetazolineSPUTOLOSIN Dembrexine
STAFAC VirginiamycinSTARCARE CetrimideSTARCARE BLUE PolyhexanideSTARIL FosinoprilSTELAZINE TrifluoperazineSTEMETIL ProchlorperazineSTENEROL HalofuginoneSTER-ZAC LIQUID TriclosanSTER-ZAC POWDER HexachlorophaneSTESOLID DiazepamSTIEDEX DesoxymethasoneSTIEMYCIN ErythromycinSTREPSILS AmylmetacresolSTREPTASE StreptokinaseSTREPTOVIN BetamethasoneSTRESNIL AzaperoneSTRINACIN TrimethoprimSTROMBA StanozololSTRONGID PyrantelSTUGERON CinnarizineSUBLIMAZE FentanylSUDAFED TriprolidineSULEO-C CarbarylSULEO-M MalathionSULFATRIM Co-trimazineSULFOXINE LA SulphamethoxypyridazineSULPAREX SulpirideSULPITIL SulpirideSULTRIN Sulphacetamide + SulphathiazoleSUMMER FLY DiazinonSUPAVERM ClosantelSUPAVERM TELMIN MebendazoleSUPRAX CefiximeSUPRECUR BuserelinSUPREFACT BuserelinSURE LevamisoleSURGAM Tiaprofenic AcidSURMONTIL TrimipramineSUROLAN Miconazole + PrednisoloneSURVANTA BeractantSUSTAMYCIN TetracyclineSUSTANON TestosteroneSWIFT PermethrinSWITCH PermethrinSYMMETREL AmantadineSYNACTHEN TetracosactrinSYNALAR FluocinoloneSYNALAR C Fluocinolone + ClioquinolSYNALAR N Fluocinolone + NeomycinSYNANTHIC OxfendazoleSYNAREL NafarelinSYNCHROCEPT FenprostaleneSYNDOL DoxylamineSYNFLEX NaproxenSYNPHASE Norethisterone
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Proprietary Name British Approved name Proprietary Name British Approved nameSYNTARIS FlunisolideSYNTOCINON OxytocinSYNTOMETRINE Ergometrine + OxytocinSYNTOPRESSIN LypressinSYNULOX Co-amoxiclavSYNURETIC AmilorideSYNUTRIM Co-trimazineSYRAPRIM TrimethoprimSYSCOR NisoldipineSYSTAMEX OxfendazoleSYTRON Sodium IronedetateTAGAMET CimetidineTAKTIC Amitraz (vet)TALIN ThaumatinTAMBOCOR FlecainideTAMOFEN TamoxifenTAMPOVAGAN StilboestrolTARDAK DelmadinoneTARGOCID TeicoplaninTARGOT ChlortetracyclineTARIVID OfloxacinTARKA VerapamilTASMAR TolcaponeTAVANIC LevofloxacinTAVEGIL ClemastineTAXOCINT TazobactamTAXOL PaclitaxelTAYLOR’S IbuprofenTAZILDIL DiltiazemTAZOCIN PiperacillinTEARS NATURALE Dextran + HypromelloseTECHNESCAN BetiatideTECHNETIUM (EHIDA)
AGENT EtifeninTEEJEL Cetalkonium Chloride + Choline
SalicylateTEGRETOL CarbamazepineTELEPAQUE Iopanoic AcidTELFAST FexofenadineTELODRON ChlorpheniramineTEMBIDS Isosorbide DinitrateTEMGESIC BuprenorphineTEMOPEN TemocillinTENIF Atenolol + NifedipineTENORET Co-tenidoneTENORETIC Co-tenidoneTENORMIN AtenololTENSIPINE NifedipineTENSIUM DiazepamTENSOLVET HeparinTEOPTIC CarteololTERFENOR TerfenadineTERFINAX TerfenadineTERMINEZE Cinchocaine + Quinalbarbitone
Sodium
TERRA-CORTRIL Oxytetracycline + PolymyxinTERRAMYCIN OxytetracyclineTERTROXIN LiothyronineTETCIN OxytetracyclineTETRA OxytetracyclineTETRA-DELTA NovOxytetracyclineobiocinTETRALYSAL LymecyclineTETRAMIN OxytetracyclineTETRAPLEX OxytetracyclineTETROXY OxytetracyclineTETSOL TetracyclineTHEO-DUR TheophyllineTHEOCARDIN DiprophyllineTHEPHORIN PhenindamineTHIBENZOLE ThiabendazoleTHIOVET ThiopentoneTHOVALINE Cod-liver OilTIAMUTIN TiamulinTICAR TicarcillinTIEMPE TrimethoprimTIGUVON Fenthion (vet)TILADE NedocromilTILARIN NedocromilTILDIEM DiltiazemTILORYTH ErythromycinTIMECEF CefodizimeTIMENTIN Clavulanic Acid + TicarcillinTIMODINE Benzalkonium ChlorideTIMOPTOL TimololTINADERM TolnaftateTIXYLIX DAYTIME PholcodineTIXYLIX NIGHT TIME PromethazineTOBRALEX TobramycinTOFRANIL ImipramineTOLANASE TolazamideTOLECTIN TolmetinTOLFEDINE Tolfenamic AcidTOMANOL PhenylbutazoneTOMUDEX RaltitrexedTONOCARD TocainideTOPAL Alginic AcidTOPAMAX TopiramateTOPICYCLINE TetracyclineTOPLINE AmitrazTORADOL KetorolacTORBETOL Benzalkonium Chloride +HexachlorophaneTORBUTROL ButorphanolTORGYL MetronidazoleTOTAMOL AtenololTRACRIUM Atracurium BesylateTRAMAKE TramadolTRAMIL ParacetamolTRANDATE LabetalolTRANXENE Clorazepic Acid
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Proprietary Name British Approved name Proprietary Name British Approved nameTRASICOR OxprenololTRASIDREX Cyclopenthiazide + OxprenololTRASYLOL AprotininTRAVOGYN IsoconazoleTRAXAM FelbinacTRENTAL OxpentifyllineTRI-ADCORTYL OTIC GramicidinTRI-ADCORTYL Gramicidin + TriamcinoloneTRI-CICATRIN BacitracinTRIAMAXCO Co-triamterzideTRIAMCO Co-triamterzideTRIBRISSEN Co-trimazineTRICHO PLUS RonidazoleTRICLOSEPT TriclosanTRIDESTRA Medroxyprogesterone + OestradiolTRILUDAN TerfenadineTRIMABAC Co-trimazineTRIMEDIAZINE Co-trimazineTRIMEDOXINE Co-trimazineTRIMOPAN TrimethoprimTRIMOVATE CREAM Clobetasone + OxytetracyclineTRIMOVATE ClobetasoneTRINACOL Co-trimazineTRINORDIOL LevonorgestrelTRINOVUM NorethisteroneTRIOMINIC PheniramineTRIOSIL Sodium MetrizoateTRIOXYL AmoxycillinTRIPACIN PhthalylsulphathiazoleTRIPTAFEN Amitriptyline + PerphenazineTRISEQUENS Norethisterone + Oestriol +
OestradiolTRITACE RamiprilTRIVETRIN Trimethoprim + SulfadoxineTROBICIN SpectinomycinTRODAX NitroxynilTROPERGEN Co-phenotropeTROPHEN NitrofurazoneTROSCAN NitroscanateTROSYL TioconazoleTRUSOPT DorzolamideTRYPLASE PancreatinTRYPTIZOL AmitriptylineTRYPTIZOL SYRUP AmitriptylineTUINAL Amylobarbitone + Quinalbarbitone
SodiumTUSANA DextromethorphanTWEEN PolysorbateTYLACARE TylosinTYLAMIX TylosinTYLAN TylosinTYLASUL PREMIX TylosinTYLUVET TylosinTYROZETS Bacitracin + TyrothricinUBRETID Distigmine Bromide
UCERAX HydroxyzineUCLAPRIM Co-trimoxazoleUKIDAN UrokinaseULTIVA RemifentanilULTRADIL FluocortoloneULTRALANUM FluocortoloneULTRAMOX AmoxycillinULTRAPROCT Cinchocaine + FluocortoloneULTRAVIST Iopronic AcidUNICAP Pantothenic AcidUNICHEM TerfenadineUNIDONE FurazolidoneUNIFLU DiphenhydramineUNIPARIN HeparinUNIPHYLLIN TheophyllineUNIPINE NifedipineUNIPRIM Co-trimazineUNIROID CinchocaineUNIVER VerapamilURANTOIN NitrofurantoinURDOX Ursodeoxycholic AcidURI-TAINER Disodium EdetateURIBEN Nalidixic AcidURIFLEX Disodium EdetateURISPAS FlavoxateUROGRAFIN Diatrizoic AcidUROMITEXAN MesnaUROVISION Diatrizoic AcidURSOFALK Ursodeoxycholic AcidURSOGAL Ursodeoxycholic AcidUTINOR NorfloxacinUTOVLAN NorethisteroneUVISTAT MexenoneVAGIFEM OestradiolVALBAZEN AlbendazoleVALCLAIR DiazepamVALIUM DiazepamVALLERGAN TrimeprazineVALOID CyclizineVALTREX ValaciclovirVANCOCIN VancomycinVANODINE CetrimideVAPONA DichlorvosVARIDASE Streptodornase + StreptokinaseVASCASE CilazaprilVASOXINE MethoxamineVECTAVIR PenciclovirVELBE VinblastineVELOSEF CephradineVELOSULIN Neutral Insulin InjectionVENOFER Iron SucroseVENTIDE Beclomethasone + SalbutamolVENTIPULMIN Clenbuterol + TrimethoprimVENTIPULMIN TMP/S Co-trimazineVENTODISKS Salbutamol
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Proprietary Name British Approved name Proprietary Name British Approved nameVENTOLIN SalbutamolVEPESID EtoposideVERAMIX MedroxyprogesteroneVERIPAQUE OxyphenisatinVERMOX MebendazoleVESADINE SulphadimidineVESANOID TretinoinVETALAR KetamineVETALOG TOPICAL TriamcinoloneVETALPHA AlfacalcidolVETASEPT ChlorhexidineVETERGESIC BuprenorphineVETIDREX HydrochlorothiazideVETKEM PhosmetVETORYL PhthalylsulphathiazoleVETRAZIN CyromazineVETREMOX AmoxycillinVETRIMOXIN AmoxycillinVETSOVATE BetamethasoneVI-SORBIN CyanocobalaminVIAGRA SildenafilVIAZEM DiltiazemVIBRAMYCIN DoxycyclineVICKS MEDINITE DoxylamineVIDAMOX AmoxycillinVIDEX DidanosineVIDOCILLIN AmpicillinVIDOPEN AmpicillinVIOFORM-HYDROCORT-
ISONE Clioquinol + HydrocortisoneVIRACEPT NelfinavirVIRAFERON Interferon AlfaVIRAMUNE NevirapineVIRAZID TribavirinVIRBAXYL XylazineVIRIDAL Alprostadil AlfadexVIRORMOME TestosteroneVIROVIR AciclovirVIRUDOX Dimethyl Sulphoxide +IdoxuridineVISCLAIR Methyl CysteineVISIPAQUE IodixanolVISKALDIX Clopamide + PindololVISKEN PindololVISTA-METHASONE BetamethasoneVISTIDE CidofovirVITBEE CyanocobalaminVIVALAN ViloxazineVIVIOPTAL Adenosine + RutosideVIVITONIN PropentofyllineVOLITAL PemolineVOLMAX SalbutamolVOLRAMAN DiclofenacVOLSAID DiclofenacVOLTAROL Diclofenac
VOREN DexamethasoneWARTICON PodophyllotoxinWAXSOL Docusate SodiumWELLDORM Chloral HydrateWELLFERON Interferon AlfaWELLVONE AtovaquoneWILLCAIN Adrenaline + ProcaineWORMALIC FenbendazoleWORMEX FenbendazoleXALATAN LatanoprostXANAX AlprazolamXATRAL AlfuzosinXENICAL OrlistatXEPIN DoxepinXYLOCAINE Adrenaline + LignocaineXYLOCARD LignocaineXYLOPROCT LignocaineXYLOTOX LignocaineYOMESAN NiclosamideYUTOPAR RitodrineZADITEN KetotifenZADSTAT MetronidazoleZAMADOL TramadolZANAFLEX TizanidineZANIDIP LercanidipineZANTAC RanitidineZAQUILAN Baquiloprim + SulphadimethoxineZARONTIN EthosuximideZAVEDOS IdarubicinZEASORB ChloroxylenolZELEPAR SelegilineZEMTARD DiltiazemZERIT StavudineZEROFEN FenbendazoleZESTORETIC LisinoprilZESTRIL LisinoprilZIDOVAL MetronidazoleZILEZE ZopicloneZIMOVANE ZopicloneZINACEF CefuroximeZINAMIDE PyrazinamideZINERYT ErythromycinZINGA NizatidineZINNAT CefuroximeZIRTEK CetirizineZISPIN MirtazapineZITA CimetidineZITHROMAX AzithromycinZOCOR SimvastatinZOFRAN OndansetronZOLADEX GoserelinZOMIG ZolmitriptanZONIVENT BeclomethasoneZONULYSIN ChymotrypsinZORAC Tazarotene
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Proprietary Name British Approved name Proprietary Name British Approved nameZOVIRAX AciclovirZUMENON OestradiolZYDOL Tramadol
ZYLORIC AllopurinolZYPREXA Olanzapine
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1
Appendix A:
Structures
These notes are provided as a guide to the semi-systematic chemical nomenclature of certain groups ofnatural and semi-synthetic products. The followingliterature should be consulted for further information.
1. The definitive rules of the International Union ofPure and Applied Chemistry (IUPAC) for organicsubstances are contained in Nomenclature of OrganicChemistry, Section A to F and H, Pergamon Press,Oxford, 1979.
2. The IUPAC rules for inorganic substances are givenin Nomenclature of Inorganic Chemistry, Blackwells,Oxford, 1990.
3. Biochemical Nomenclature and Related Documents, TheBiochemical Society for the International Union ofBiochemistry (IUB), 2nd. edn. London, 1992. Thefollowing topics are included.
Stereochemistry(Nomenclature of Organic Chemistry, Section E)
Natural products and related compounds(Nomenclature of Organic Chemistry, Section F)
Abbreviations and Symbols
Amino acids, peptides, peptide hormones andimmunoglobulins
Steroids
Carotenoids and tocopherols
Carbohydrates and cyclitols
Vitamins
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2A Aminoglycoside Antibiotics
A.1 The aminoglycoside antibiotics are conveniently named by reference to2-D-deoxystreptamine, 1, in which name the configuration andnumbering shown are implicit.
OH
NH2
NH2
HO
OH
1
1
3
4
5 6
2
A.2 The aminoglycoside antibiotics commonly carry glycosyl radicals on theoxygen atoms attached to C-4 and C-6. The configuration andnumbering shown in 1 should be strictly observed if confusion is to beavoided.
A.3 When one glycosyl radical is linked to another the names are separatedby two locants which indicate the respective positions involved in thisglycosidic union; these locants are enclosed in parentheses andseparated by an arrow (pointing from the locant corresponding to theglycosyl carbon atom to the locant corresponding to the hydroxyliccarbon atom involved).
B Cephalosporin Antibiotics
B.1 The cephalosporin antibiotics are conveniently named by reference toeither cephalosporanic acid (2, R = CH2OAc, X = H) or cephem-4-carboxylic acid (2, R = X = H).
8
7 6
5 43
21
N
S
O
HH
X
R
COOH
2
8
7 65
4
32
1N
S
COOH
R
X
H H
O
3
B.2 When names are based on cephalosporanic acid or cephem-4-carboxylicacid the traditional numbering shown in 2 is used.
B.3 Cephalosporanic acid is systematically named as (6R)-3-acetoxymethyl-8-oxo-5-thia-1-azabicyclo[4.2.0]oct-2-ene-2-carboxylic acid.Compounds that are named systematically use the numbering andorientation shown in 3.
B.4 The cephalosporin antibiotics are ususally 7-acylaminocephalosporanicacid derivatives in which the configuration at position 7 is R.
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3C Ergot Alkaloids
C.1 Members of the ergoline group of substances are conveniently named byreference to either ergoline itself, 4, or to D-lysergamide, 5. When namesare so based the traditional numbering shown in 4 is used. In 9,10-dihydro compounds the configuration at position-10 needs to bespecified.
NH
HN
H
HNMe
HN
H
CONH2H
NMe
HN
H
H N
N
ON
H
1 2
3
4
5
6
78
9
10
1112
13
1415
18 19
4
1′2′
3′ 4′5′
6′
7′8′
9′10′
11′12′
H
5 6
C.2 Members of the ergotamine group of substances are conveniently namedby reference to ergotaman, 6. Ergotamine itself is (5¢R)-5¢-benzyl-12¢-hydroxy-2¢-methyl-18-oxoergotaman-3¢,6¢-dione.
D Morphines
D.1 Members of the morphine and codeine group of substances havetraditionally been named with reference to morphine itself, 7, using thenumbering shown. However, names may be based more conveniently oneither morphinan, 8, orent-morphinan, 9.
987
NHH
NH
12
3
4
5
67
8
9
1011
12
13 1415 16
9a17
16151413
1211
10
9
87
6
5
4
32
1
HO
HO
NH
Me
O
H
D.2 Morphine, 7, is (5R, 6S)-4,5-epoxy-9a-methyl-7,8-didehydromorphinan-3,6-diol.
D.3 In certain morphine derivatives, an etheno or ethano bridge is presentjoining positions 6 and 14 and a hydroxyalkyl side chain is present atposition 7.
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4E Penicillin Antibiotics
E.1 The penicillin antibiotics are conveniently named by reference topenicillanic acid (10, X = H) when the classical numbering shown isused.
N
SHH
X
O
MeMe
COOH
H
N
SHH
HO COOH
MeMe
X
12
34
56
7
7
6 54
3
21
10 11
E.2 Penicillanic acid is systematically named as (2S, 5R)-3,3-dimethyl-7-oxo-4-thia-1-azabicyclo[3.2.0]heptane-2-carboxylic acid. Compounds thatare named systematically use the orientation and numbering shown in11.
E.3 The penicillin antibiotics are usually 6-acylamino penicillanic acidderivatives in which the configuration at position 6 is R.
F Polypeptides
F.1 The following 3-letter and 1-letter symbols for amino-acids, authorisedby the IUPAC-IUB Joint Commission on Biochemical Nomenclature,are used for representing the sequences of polypeptides:
Alanine Ala A Leucine Leu L
Arginine Arg R Lysine Lys K
Asparagine Asn N Methionine Met M
Aspartic Acid Asp D Phenylalanine Phe F
Cysteine Cys C Proline Pro P
Glutamine Gln Q Serine Ser S
Glutamic acid Glu E Threonine Thr T
Glycine Gly G Tryptophan Trp W
Histidine His H Tyrosine Tyr Y
Isoleucine Ile I Valine Val V
F.2 The following symbols recommended by the Joint Commission are alsoused:
2-Aminohexanoic acid Ahx
Sarcosine Sar
Pyroglyutamic acid <Glu
tert-Butoxycarbonyl Boc
F.3 When interpreting 3-letter sequences of amino-acid residues, the hyphen
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5should be considered as part of the symbol. Its use to separate theindividual residues or radicals may be illustrated by the followingexample:
Gly = NH2 CH2 COOH
Gly- = NH2 CH2 CO-
-Gly = -NH CH2 COOH
-Gly- = -NH CH2 CO-
and thus,
Gly-Gly-Gly = NH2 CH2 CO NH CH2 CO NH CH2 COOH
The residues are conventionally written with the amino group to the leftand the carboxyl group to the right. This is implicit in the symbolism.
F.4 Where peptide sequences are shown using 3-letter symbols all amino-acids except glycine have the L-configuration unless otherwise indicated.
G Prostaglandins
G.1 Members of the prostaglandin group of substances are convenientlynamed by reference to prostanoic acid, 12, using the numbering shown.Prostanoic acid may be systematically named as 7-[(1S, 2S)-2-octylcyclopentyl]heptanoic acid. Dinoprost, 13, may therefore benamed as (5Z, 12E)-(9S,11R,15S)-9,11,15-trihydroxyprosta-5,13-dienoic acid.
COOH
CH3
H
H
178
9
10
11 1213 20 CH3
H
H
COOH
OH
HO
HO
H
H H
12 13
G.2 A convenient semi-trivial nomenclature exists by which prostaglandins(PG) are classified into groups A to F according to the substitutionpattern in the cyclopentane ring (shown below). The subscript numerals1, 2 and 3 refer to the number of double bonds found in the side-chainsand subscript a refers to the configuration of the C-9 hydroxy group.Thus, 13 is referred to as PGF2a
O O O OH
OHH
O
OHH
O
HOH
A B C D E F
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6H Steroids
H.1 Steroids are drawn and numbered, and the rings lettered, as shown in14.
A B
C D1
2
34
56
7
8910
1112
13
14 15
16
17
18
19
20
21
2223
24
241
242
25
26
27
H
H
H
H
H
R1
R2R3
14 15
H.2 Steroids are named with reference to certain basic carbocycles some ofwhich are defined in Table 1. When so drawn, dotted bonds are regardedas lying below the plane of the paper and are designated a, thickenedbonds are regarded aslying above the plane of the paper and aredesignated b and bonds of unknown configuration are shown by a wavyline and are designated x.
Table I
R1 R2 R3
Gonane H H H
Estrane H Me H
Androstane Me Me H
Pregnane Me Me Et
H.3 When the hydrogen atom at C-5 is present, its configuration is alwaysspecified, eg 5a-pregnane, 5b-androstane. The configuration at centres,8,9,10,13,14 and 17 is assumed to be as shown in 15 unless otherwisespecified.
H.4 When inversion of the normal configuration occurs, the positionsconcerned are specified; and thus 17 is named 5b,17a-pregnane.
16
H
H
H
H
H
Me
Me Me
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7H.5 When inversion occurs at all of the defined asymmetric centres, the
original name is preceded by the italicised prefix ent-. Racemates areindicated by use of the italicised prefix rac-.
H.6 Further fundamental carbocycles are defined thus:
Table II
Side-chain carbon positions present
Cholane 20 - 24
Cholestane 20 - 27
Ergostane 20 - 27, 241
In addition to retaining the configuration shown in 15, C-20 has anR-configuration in each carbocycle and C-24 in ergostane has an S-configuration. However, additional substituents at positions C-17, C-20,C-21 may alter the R and S propriety descriptions without any change atC-20.
H.7 A large number of therapeutically active steroids bear a carbonyl groupat position 3 and unsaturation across positions 5 and 5. Ring A is oftenaromatic in estrogens.
J Tetracyclines
J.1 The tetracycline antibiotics are conveniently named by reference totetracycline itself, 17, (R = H), which may be defined as(4S,4aS,5aS,6S,12aS)-4-dimethylamino-1,4,4a,5,5a,6,11,12a-octahydro-3,6,10,12,12a-pentahydroxy-6-methyl-1,11-dioxonaphthacene-2-carboxamide.
OH O OHOH
O
CONH2
OH
NMe2
HHMe
HO
H R
17
J.2 When analogues of tetracycline are named the stereodescriptors R and Smay be subject to change even though the steric configuration usuallyremains unchanged. For example, in oxytetracycline, the hydroxyl groupat position 5 imposes assignment inversions at positions 4a and 5a fromS to R although the steric configuration at these positions remainsunchanged.
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8J.3 When fully systematic names based on naphthacene-2-carboxamine are
used, the stereodescriptors given in Table 3 should be used.
Table III
Position
4 4a 5 5a 6 12a
Chlortetracycline S S – S S S
Clomocycline S S – S S S
Demeclocycline S S – S S S
Doxycycline S R S R R S
Meclocycline S R S R – S
Methacycline S R S R – S
Minocycline S S – R – S
Oxytetracycline S R S R S S
Tetracycline S S – S S S
K Tropanes
K.1 Members of the tropane group of substances are conveniently named byreferences to tropane itself, 18, when the numbering and orientationshown are used. Tropane is defined as (8r)-N-methyl-8-azabicyclo[3.2.1]octane.
NMe
1
2
3
46
5
7
8
18
NMe
O
H
O
H Ph
OH
19
K.2 Atropine, 19, is (1R, 3r, 5S, 8r,)-tropan-3-yl (RS)-tropate where theterm tropate represents 3-hydroxy-2-phenylpropionate.
K.3 In the (-) -series the tropoyl side-chain has the (S) configuration, 20.
K.4 In y-tropane compounds, 21, the configuration at position-3 isdesignated as ‘3s’.
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9K.5 In hyoscine and other atropine derivatives bearing a 6,7-epoxy bridge,
the configuration is as shown in 22.
O
O
H Ph
OH
20
H
O
O
PhH
OH
21 22
NMe
O
M Xanthines
Members of the xanthine group of substances are conveniently namedby references to purine, 24, when the non-systematic numbering shownis used.
N
N
N
N
H
12
3 4
56
78
9
23
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1
Appendix B:
Guidelines for the Constructionof Pharmaceutical Trademarks
These guidelines are concerned with the following aspects:
1. Undesirable features in trade marks, both registeredand unregistered
2. The qualification of trade marks by detached words,letters and numerals
3. The relationship between trade marks andnonproprietary names
Guidelines
1. 1.1 A trade mark should not be liable to confusion in print, inhandwriting or in speech with a trade mark of an existingproduct.
1.2 A trade mark should not consist wholly of initial letters (otherthan acronyms) or code numbers.
1.3 A trade mark should not convey misleading therapeutic orpharmaceutical connotations.
1.4 Variations of a trade mark consisting of a single word within arange of related products should not be so small as to causeconfusion.
1.5 A trade mark of a discontinued product consisting of a singleactive ingredient should not be reassigned to a product contain-ing a different single active ingredient.
2. 2.1 Indication of the strength of a product by words such as ‘Forte’and ‘Strong’ in the trade mark should be avoided.
2.2 Unnecessary qualification of a trade mark by letters shouldgenerally be avoided but letters when used should conform tothe indications stated in the Annex.
2.3 Qualification of a trade mark by a detached Roman numeralshould generally be avoided.
2.4 Qualification of a trade mark by the numbers 1 to 5 should beavoided.
2.5 With the exception of oral contraceptive products, numberswhen used to qualify a trade mark should indicate the strengthof the active ingredient.
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23. 3.1 A trade mark should not be liable to confusion in handwriting, in
print or in speech with an established nonproprietary namerelating to a different active ingredient.
3.2 Resolution 46.19 passed at the 1993 World Health Assemblyrequires that a trade mark should not incorporate a ‘commonstem’ that has been adopted and published by the Organization.The Resolution also discourages the use of trade marks derivedfrom International Nonproprietary Names. These requirementsshould be observed.
ANNEX
Detached letters when used to qualify a trade mark should conform tothe following indications (non-limiting list). It is recommended thatdouble-letter appendages be used for added distinctiveness.
If any of the following letters are used, their significance should accordwith the corresponding statements. Conversely, if the need exists toconvey a concept that is stated below, the corresponding letter(s) shouldbe used.
The list of letter-combinations published in previous editions of this book iscurrently being reviewed. When finalised, it will be issued once more in aSupplment to this edition.